EE05249B1 - (E)-5-(2-bromovinl)-2'-desoksuridiini valmistamise meetod - Google Patents

(E)-5-(2-bromovinl)-2'-desoksuridiini valmistamise meetod

Info

Publication number
EE05249B1
EE05249B1 EEP200300402A EEP200300402A EE05249B1 EE 05249 B1 EE05249 B1 EE 05249B1 EE P200300402 A EEP200300402 A EE P200300402A EE P200300402 A EEP200300402 A EE P200300402A EE 05249 B1 EE05249 B1 EE 05249B1
Authority
EE
Estonia
Prior art keywords
deoxidine
bromovin
uridine
preparation
deoxidine uridine
Prior art date
Application number
EEP200300402A
Other languages
English (en)
Inventor
Salimbeni Aldo
Alberto Maggi Carlo
Manzini Stefano
Turozzi Damiano
Original Assignee
Menarini Ricerche S.P.A.
Berlin-Chemie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7675814&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE05249(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Menarini Ricerche S.P.A., Berlin-Chemie Ag filed Critical Menarini Ricerche S.P.A.
Publication of EE200300402A publication Critical patent/EE200300402A/et
Publication of EE05249B1 publication Critical patent/EE05249B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)
EEP200300402A 2001-02-28 2002-02-21 (E)-5-(2-bromovinl)-2'-desoksuridiini valmistamise meetod EE05249B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10109657A DE10109657A1 (de) 2001-02-28 2001-02-28 Verfahren zur Herstellung von (E)-5-(2-Bromvinyl)-2`-desoxyuridin
PCT/EP2002/001833 WO2002068443A1 (en) 2001-02-28 2002-02-21 Process for the preparation of (e)-5-(2-bromovinyl)-2'-deoxyuridine

Publications (2)

Publication Number Publication Date
EE200300402A EE200300402A (et) 2003-12-15
EE05249B1 true EE05249B1 (et) 2009-12-15

Family

ID=7675814

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300402A EE05249B1 (et) 2001-02-28 2002-02-21 (E)-5-(2-bromovinl)-2'-desoksuridiini valmistamise meetod

Country Status (32)

Country Link
US (1) US6864366B2 (et)
EP (1) EP1363928B1 (et)
JP (1) JP2004521132A (et)
KR (1) KR100853280B1 (et)
CN (1) CN1219789C (et)
AR (1) AR032908A1 (et)
AT (1) ATE294810T1 (et)
BG (1) BG66333B1 (et)
BR (1) BRPI0207566B8 (et)
CA (1) CA2439319C (et)
CZ (1) CZ299318B6 (et)
DE (2) DE10109657A1 (et)
DK (1) DK1363928T3 (et)
EA (1) EA006156B1 (et)
EE (1) EE05249B1 (et)
ES (1) ES2239713T3 (et)
HK (1) HK1060134A1 (et)
HR (1) HRP20030671B1 (et)
HU (1) HU229136B1 (et)
IL (2) IL157573A0 (et)
MA (1) MA26267A1 (et)
MX (1) MXPA03007624A (et)
MY (1) MY133371A (et)
PE (1) PE20020892A1 (et)
PL (1) PL210150B1 (et)
PT (1) PT1363928E (et)
RS (1) RS50761B (et)
SK (1) SK287283B6 (et)
TN (1) TNSN03049A1 (et)
UA (1) UA75110C2 (et)
WO (1) WO2002068443A1 (et)
ZA (1) ZA200306639B (et)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101066987B (zh) * 2007-06-14 2010-05-19 上海交通大学 溴呋啶的制备方法
LT3447061T (lt) 2011-03-01 2022-01-25 NuCana plc Farmacinė vaisto forma, apimanti 5-fluor-2'-deoksiuridinofosforamidato darinį, skirtą naudoti vėžio gydymui
GB201715011D0 (en) 2017-09-18 2017-11-01 Nucana Biomed Ltd Floxuridine synthesis
CN115043894A (zh) * 2022-06-22 2022-09-13 华润双鹤药业股份有限公司 一种溴夫定起始物料异构体单晶及其制备方法和应用
KR20240086637A (ko) 2022-12-10 2024-06-18 (주)일승 Ptc 히터

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB215399A (en) * 1922-11-07 1924-05-07 Frederic Valerius Hetzel Improvements in sprocket-wheels
GB1601020A (en) 1978-04-24 1981-10-21 Stichting Grega Vzw 2'-deoxy-5 (2-halogenovinyl)-uridines
HU187736B (en) * 1982-08-04 1986-02-28 Mta Koezponti Kemiai Kutato Intezet,Hu Process for producing /e/ -5-/2-bromovinyl/-2-comma above-deoxyuridine and o-acyl derivatives
US5220062A (en) * 1991-05-06 1993-06-15 Ciba-Geigy Corporation Process for the preparation of benezenesulfonamides

Also Published As

Publication number Publication date
SK10642003A3 (sk) 2004-01-08
TNSN03049A1 (en) 2005-12-23
DE60203998D1 (de) 2005-06-09
HRP20030671B1 (en) 2011-11-30
HK1060134A1 (en) 2004-07-30
EA200300761A1 (ru) 2004-02-26
CZ299318B6 (cs) 2008-06-18
PT1363928E (pt) 2005-07-29
ATE294810T1 (de) 2005-05-15
BRPI0207566B8 (pt) 2021-05-25
PL210150B1 (pl) 2011-12-30
WO2002068443A1 (en) 2002-09-06
YU67103A (sh) 2006-05-25
UA75110C2 (en) 2006-03-15
CN1219789C (zh) 2005-09-21
HUP0303323A3 (en) 2008-12-29
JP2004521132A (ja) 2004-07-15
US20040077586A1 (en) 2004-04-22
AR032908A1 (es) 2003-12-03
EE200300402A (et) 2003-12-15
ZA200306639B (en) 2004-08-26
EA006156B1 (ru) 2005-10-27
HRP20030671A2 (en) 2005-06-30
IL157573A0 (en) 2004-03-28
MA26267A1 (fr) 2004-09-01
MY133371A (en) 2007-11-30
EP1363928B1 (en) 2005-05-04
DK1363928T3 (da) 2005-12-12
RS50761B (sr) 2010-08-31
SK287283B6 (sk) 2010-05-07
HU229136B1 (en) 2013-08-28
CN1494550A (zh) 2004-05-05
BR0207566A (pt) 2004-09-14
ES2239713T3 (es) 2005-10-01
DE10109657A1 (de) 2002-09-05
BRPI0207566B1 (pt) 2019-04-24
EP1363928A1 (en) 2003-11-26
HUP0303323A2 (hu) 2004-01-28
DE60203998T2 (de) 2005-09-22
KR20030081465A (ko) 2003-10-17
PE20020892A1 (es) 2002-12-26
KR100853280B1 (ko) 2008-08-20
BG66333B1 (bg) 2013-06-28
MXPA03007624A (es) 2003-12-04
US6864366B2 (en) 2005-03-08
PL363611A1 (en) 2004-11-29
IL157573A (en) 2009-09-22
CZ20032295A3 (cs) 2004-01-14
CA2439319A1 (en) 2002-09-06
BG108129A (bg) 2004-12-30
CA2439319C (en) 2010-10-19

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20101231