EE05240B1 - Orto- ja meta-asendatud bisarlhendid, nende kasutamine ja neid sisaldavad farmatseutilised preparaadid - Google Patents
Orto- ja meta-asendatud bisarlhendid, nende kasutamine ja neid sisaldavad farmatseutilised preparaadidInfo
- Publication number
- EE05240B1 EE05240B1 EEP200300183A EEP200300183A EE05240B1 EE 05240 B1 EE05240 B1 EE 05240B1 EE P200300183 A EEP200300183 A EE P200300183A EE P200300183 A EEP200300183 A EE P200300183A EE 05240 B1 EE05240 B1 EE 05240B1
- Authority
- EE
- Estonia
- Prior art keywords
- bisar
- ortho
- meta
- substituted
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10059418A DE10059418A1 (de) | 2000-11-30 | 2000-11-30 | Ortho, meta-substituierte Bisarylverbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| PCT/EP2001/013294 WO2002044137A1 (de) | 2000-11-30 | 2001-11-17 | Ortho, meta-substituierte bisarylverbindungen, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltende pharmazeutische zubereitungen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE200300183A EE200300183A (et) | 2003-06-16 |
| EE05240B1 true EE05240B1 (et) | 2009-12-15 |
Family
ID=7665215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200300183A EE05240B1 (et) | 2000-11-30 | 2001-11-17 | Orto- ja meta-asendatud bisarlhendid, nende kasutamine ja neid sisaldavad farmatseutilised preparaadid |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US6605625B2 (cs) |
| EP (1) | EP1339675B1 (cs) |
| JP (1) | JP4051283B2 (cs) |
| KR (1) | KR100968056B1 (cs) |
| CN (1) | CN1290825C (cs) |
| AR (1) | AR031430A1 (cs) |
| AT (1) | ATE289292T1 (cs) |
| AU (2) | AU2002227931B2 (cs) |
| BR (1) | BR0115769A (cs) |
| CA (1) | CA2430273C (cs) |
| CZ (1) | CZ301631B6 (cs) |
| DE (2) | DE10059418A1 (cs) |
| EE (1) | EE05240B1 (cs) |
| ES (1) | ES2236341T3 (cs) |
| HR (1) | HRP20030436B1 (cs) |
| HU (1) | HUP0303317A3 (cs) |
| IL (2) | IL156097A0 (cs) |
| MX (1) | MXPA03004386A (cs) |
| NO (1) | NO328599B1 (cs) |
| NZ (1) | NZ526177A (cs) |
| PL (1) | PL206245B1 (cs) |
| PT (1) | PT1339675E (cs) |
| RS (1) | RS50403B (cs) |
| RU (1) | RU2278858C2 (cs) |
| SK (1) | SK286708B6 (cs) |
| TW (1) | TWI254039B (cs) |
| WO (1) | WO2002044137A1 (cs) |
| ZA (1) | ZA200303893B (cs) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10060807A1 (de) * | 2000-12-07 | 2002-06-20 | Aventis Pharma Gmbh | Ortho, ortho-substituierte stickstoffhaltige Bisarylverbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| GB0124934D0 (en) * | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
| GB0124936D0 (en) * | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
| GB0124941D0 (en) * | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
| GB0124931D0 (en) * | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
| GB0124939D0 (en) * | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
| GB0124933D0 (en) * | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
| GB0124938D0 (en) * | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
| ES2400486T3 (es) * | 2002-02-12 | 2013-04-10 | Glaxosmithkline Llc | Derivados de nicotinamida útiles como inhibidores de p38 |
| GB0217757D0 (en) | 2002-07-31 | 2002-09-11 | Glaxo Group Ltd | Novel compounds |
| DE60305053T2 (de) | 2002-08-19 | 2006-08-31 | Glaxo Group Ltd., Greenford | Pyrimidinderivate als selektive cox-2-inhibitoren |
| GB0221443D0 (en) | 2002-09-16 | 2002-10-23 | Glaxo Group Ltd | Pyridine derivates |
| AU2003291839B2 (en) * | 2002-12-13 | 2009-01-22 | Ym Biosciences Australia Pty Ltd | Nicotinamide-based kinase inhibitors |
| ES2571779T3 (es) * | 2002-12-13 | 2016-05-26 | Ym Biosciences Australia Pty | Inhibidores de cinasa a base de nicotinamida |
| WO2004054977A1 (en) * | 2002-12-13 | 2004-07-01 | Cytopia Pty Ltd | Nicotinamide-based kinase inhibitors |
| GB0308185D0 (en) * | 2003-04-09 | 2003-05-14 | Smithkline Beecham Corp | Novel compounds |
| GB0315950D0 (en) | 2003-06-11 | 2003-08-13 | Xention Discovery Ltd | Compounds |
| DE10341233A1 (de) * | 2003-09-08 | 2005-03-24 | Aventis Pharma Deutschland Gmbh | Kombination von Phenylcarbonsäureamiden mit beta-Adrenozeptoren-Blockern und deren Verwendung zur Behandlung von Vorhofarrhythmien |
| US20050054673A1 (en) * | 2003-09-08 | 2005-03-10 | Aventis Pharma Deutschland Gmbh | Combination of phenylcarboxylic acid amides with beta-adrenoreceptor blockers and their use for the treatment of atrial arrhythmias |
| JP4794446B2 (ja) * | 2003-09-23 | 2011-10-19 | メルク・シャープ・エンド・ドーム・コーポレイション | イソキノリン系カリウムチャンネル阻害薬 |
| US7647300B2 (en) * | 2004-01-26 | 2010-01-12 | Google Inc. | Methods and systems for output of search results |
| GB0402143D0 (en) * | 2004-01-30 | 2004-03-03 | Smithkline Beecham Corp | Novel compounds |
| GB0403744D0 (en) * | 2004-02-20 | 2004-03-24 | Astrazeneca Ab | Chemical process |
| WO2005087236A1 (en) * | 2004-03-11 | 2005-09-22 | Glaxo Group Limited | Novel m3 muscarinic acetylcholine receptor antagonists |
| GB0412986D0 (en) | 2004-06-10 | 2004-07-14 | Xention Discovery Ltd | Compounds |
| EP1776355B1 (en) * | 2004-07-29 | 2013-06-12 | Merck Sharp & Dohme Corp. | Potassium channel inhibitors |
| US7569589B2 (en) | 2004-07-29 | 2009-08-04 | Merck & Co., Inc. | Potassium channel inhibitors |
| US20080051416A1 (en) * | 2004-10-05 | 2008-02-28 | Smithkline Beecham Corporation | Novel Compounds |
| EP1957075A4 (en) | 2004-11-15 | 2009-11-18 | Glaxo Group Ltd | NOVEL ANTAGONISTS OF ACETYLCHOLINE M3 TYPE MUSCARINIC RECEPTORS |
| US7576212B2 (en) | 2004-12-09 | 2009-08-18 | Xention Limited | Thieno[2,3-B] pyridines as potassium channel inhibitors |
| GB0512429D0 (en) * | 2005-06-17 | 2005-07-27 | Smithkline Beecham Corp | Novel compound |
| CA2615440A1 (en) * | 2005-07-22 | 2007-02-08 | Merck & Co., Inc. | Potassium channel inhibitors |
| GB0525164D0 (en) | 2005-12-09 | 2006-01-18 | Xention Discovery Ltd | Compounds |
| NZ572231A (en) * | 2006-04-27 | 2010-12-24 | Sanofi Aventis Deutschland | Inhibitors of the task-1 and task-3 ion channel |
| CL2008000066A1 (es) | 2007-01-12 | 2008-08-01 | Smithkline Beecham Corp | Compuestos derivados de (5-hidroxi-3-oxo-2,3-dihidropiridazina-4-carbonil)glicina, inhibidores de hif prolil hidroxilasas; procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso en el tratamiento de la anem |
| WO2008124614A1 (en) * | 2007-04-06 | 2008-10-16 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
| CL2008000985A1 (es) | 2007-04-06 | 2008-10-10 | Neurocrine Biosciences Inc | Compuesto derivado de heterociclos de nitrogeno, agonistas del receptor gnrh; composicion farmaceutica que comprende a dicho compuesto; y uso para tratar una afeccion relacionada con las hormonas sexuales, endometriosis, dismenorrea, enfermedad de ov |
| GB0815784D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB0815782D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB0815781D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB201105659D0 (en) | 2011-04-01 | 2011-05-18 | Xention Ltd | Compounds |
| NO3175985T3 (cs) | 2011-07-01 | 2018-04-28 | ||
| JP2015504923A (ja) | 2012-01-27 | 2015-02-16 | ギリアード サイエンシーズ， インコーポレイテッド | 後期ナトリウムイオンチャネル遮断剤およびカリウムイオンチャネル遮断剤を使用する併用療法 |
| TW202246215A (zh) | 2015-12-18 | 2022-12-01 | 美商亞德利克斯公司 | 作為非全身ｔｇｒ５促效劑之經取代之４－苯基吡啶化合物 |
| US12084472B2 (en) | 2015-12-18 | 2024-09-10 | Ardelyx, Inc. | Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists |
| CN107573292B (zh) * | 2017-09-04 | 2022-06-24 | 江苏艾立康医药科技有限公司 | 作用于脯氨酰羟化酶的吡嗪衍生化合物 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE59107440D1 (de) * | 1990-02-19 | 1996-04-04 | Ciba Geigy Ag | Acylverbindungen |
| GB9220137D0 (en) * | 1992-09-23 | 1992-11-04 | Pfizer Ltd | Therapeutic agents |
| CA2166413A1 (en) * | 1993-06-30 | 1995-01-12 | Richard James Arrowsmith | Anti-atherosclerotic diaryl compounds |
| GB9416972D0 (en) * | 1994-08-23 | 1994-10-12 | Smithkline Beecham Plc | Carbon side chain/indole/indolene |
| DE4430638A1 (de) * | 1994-08-29 | 1996-03-07 | Bayer Ag | Verwendung von substituierten 4-Phenyl-6-amino-nicotinsäurederivaten als Arzneimittel |
| DE4432101A1 (de) | 1994-09-09 | 1996-03-14 | Hoechst Ag | Aminosäure-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| US5670504A (en) | 1995-02-23 | 1997-09-23 | Merck & Co. Inc. | 2,6-diaryl pyridazinones with immunosuppressant activity |
| US6083986A (en) * | 1996-07-26 | 2000-07-04 | Icagen, Inc. | Potassium channel inhibitors |
| US5935945A (en) | 1996-10-31 | 1999-08-10 | Merck & Co., Inc. | Methods of treating or preventing cardiac arrhythmia |
| US5969017A (en) | 1996-10-31 | 1999-10-19 | Merck & Co., Inc. | Methods of treating or preventing cardiac arrhythmia |
| KR100241350B1 (ko) * | 1997-10-27 | 2000-02-01 | 정선종 | 전자 거래에서 안전한 전자 공증문서 생성방법 |
| US6333337B1 (en) * | 1998-01-27 | 2001-12-25 | Icagen, Inc. | Potassium channel inhibitors |
| JP2002523451A (ja) * | 1998-09-01 | 2002-07-30 | ブリストル−マイヤーズ スクイブ カンパニー | カリウムチャネル抑制剤および方法 |
| KR20010079782A (ko) * | 1998-09-11 | 2001-08-22 | 에가시라 구니오 | 벤젠 유도체 및 이의 의약 용도 |
| DE19947457A1 (de) * | 1999-10-02 | 2001-04-05 | Aventis Pharma Gmbh | 2'-Substituierte 1,1'-Biphenyl-2-carbonamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie enthaltende pharmazeutische Zubereitungen |
-
2000
- 2000-11-30 DE DE10059418A patent/DE10059418A1/de not_active Withdrawn
-
2001
- 2001-11-17 EE EEP200300183A patent/EE05240B1/xx not_active IP Right Cessation
- 2001-11-17 DE DE50105386T patent/DE50105386D1/de not_active Expired - Lifetime
- 2001-11-17 RU RU2003119153/04A patent/RU2278858C2/ru not_active IP Right Cessation
- 2001-11-17 WO PCT/EP2001/013294 patent/WO2002044137A1/de active IP Right Grant
- 2001-11-17 HU HU0303317A patent/HUP0303317A3/hu unknown
- 2001-11-17 IL IL15609701A patent/IL156097A0/xx unknown
- 2001-11-17 HR HR20030436A patent/HRP20030436B1/xx not_active IP Right Cessation
- 2001-11-17 AU AU2002227931A patent/AU2002227931B2/en not_active Ceased
- 2001-11-17 ES ES01989479T patent/ES2236341T3/es not_active Expired - Lifetime
- 2001-11-17 CN CNB01819740XA patent/CN1290825C/zh not_active Expired - Fee Related
- 2001-11-17 BR BR0115769-8A patent/BR0115769A/pt not_active Application Discontinuation
- 2001-11-17 CA CA2430273A patent/CA2430273C/en not_active Expired - Fee Related
- 2001-11-17 MX MXPA03004386A patent/MXPA03004386A/es active IP Right Grant
- 2001-11-17 EP EP01989479A patent/EP1339675B1/de not_active Expired - Lifetime
- 2001-11-17 PT PT01989479T patent/PT1339675E/pt unknown
- 2001-11-17 SK SK653-2003A patent/SK286708B6/sk not_active IP Right Cessation
- 2001-11-17 RS YUP-376/03A patent/RS50403B/sr unknown
- 2001-11-17 AU AU2793102A patent/AU2793102A/xx active Pending
- 2001-11-17 JP JP2002546507A patent/JP4051283B2/ja not_active Expired - Fee Related
- 2001-11-17 AT AT01989479T patent/ATE289292T1/de active
- 2001-11-17 KR KR1020037007255A patent/KR100968056B1/ko not_active Expired - Fee Related
- 2001-11-17 NZ NZ526177A patent/NZ526177A/en unknown
- 2001-11-17 PL PL362700A patent/PL206245B1/pl not_active IP Right Cessation
- 2001-11-17 CZ CZ20031502A patent/CZ301631B6/cs not_active IP Right Cessation
- 2001-11-28 TW TW090129358A patent/TWI254039B/zh not_active IP Right Cessation
- 2001-11-28 AR ARP010105540A patent/AR031430A1/es unknown
- 2001-11-29 US US09/995,771 patent/US6605625B2/en not_active Expired - Fee Related
-
2003
- 2003-05-20 ZA ZA200303893A patent/ZA200303893B/en unknown
- 2003-05-25 IL IL156097A patent/IL156097A/en not_active IP Right Cessation
- 2003-05-28 NO NO20032438A patent/NO328599B1/no not_active IP Right Cessation
- 2003-06-04 US US10/453,646 patent/US6924392B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EE05240B1 (et) | Orto- ja meta-asendatud bisarlhendid, nende kasutamine ja neid sisaldavad farmatseutilised preparaadid | |
| EE05183B1 (et) | Asabitsklilised hendid, nende valmistamine ja kasutamine ravimitena ning neid sisaldav farmatseutiline kompositsioon | |
| EE200300077A (et) | Bitsüklilised heterotsüklilised ühendid, neid ühendeid sisaldavad ravimid, nende kasutamine ja meetodid nende valmistamiseks | |
| EE200300300A (et) | Kinasoliinderivaadid, neid ühendeid sisaldavad ravimid, nende kasutamine ja meetod nende valmistamiseks | |
| NO20024175D0 (no) | Azetidinderivater, deres fremstilling og farmasöytiske forbindelser inneholdende de samme | |
| EE200200138A (et) | Kinolüülpropüülpiperidiini derivaadid, nende valmistamine ja neid sisaldavad kompositsioonid | |
| EE200200149A (et) | Kinasoliinühendid ja neid sisaldavad ravimkoostised | |
| EE200000168A (et) | Karboksamidotiasoolderivaadid, nende valmistamine ja neid sisaldavad farmatseutilised kompositsioonid | |
| EE200100695A (et) | Bitsüklilised heterotsüklilised ühendid, neid ühendeid sisaldavad ravimid, nende kasutamine ja meetodid nende valmistamiseks | |
| NO20030139L (no) | Farmasöytiske preparater inneholdende DDS forbindelser | |
| EE200300080A (et) | Polüarüülkarboksamiidühendid, nende valmistamine ja kasutamine lipiiditaset alandavate toimeainetena ning neid sisaldav farmatseutiline kompositsioon | |
| NO20071303L (no) | Farmasoytiske preparater | |
| EE200300110A (et) | Kaneelhappe asendatud guanidiidid, nende valmistamine ja kasutamine ravimitena ning neid sisaldav ravim | |
| NO20006138D0 (no) | Substituerte indolinoner, fremstilling og anvendelse derav som medikamenter | |
| NO985368L (no) | Substituerte imidazolidinderivater, deres fremstilling, deres anvendelse og farmas°ytiske preparater inneholdende forbindelsene | |
| EE200300254A (et) | Heterotsüklilised ühendid, millel on antibakteriaalne toime, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsioonid | |
| EE200200041A (et) | Karboksüülhappeamiidid, neid ühendeid sisaldavad ravimid, nende kasutamine ja valmistamine | |
| EE05196B1 (et) | Heteroarlsulfonlklgahelaga antraniilamiidid, nende valmistamine ja kasutamine ravimina ning neid sisaldavad ravimpreparaadid | |
| DK1006110T3 (da) | Derivater af acylpiperazinylpyrimidiner, fremstilling deraf og anvendelse som lægemidler | |
| EE200000621A (et) | Pikornaviirusevastased ühendid, nende valmistamine ja kasutamine | |
| NO20005146L (no) | Tienylazolylalkoksyetanaminer, deres fremstilling og deres anvendelse som medikamenter | |
| EE200200220A (et) | Uudsed tsüklopropaanid kui CGRP antagonistid, neid ühendeid sisaldavad ravimid ja meetodid nende valmistamiseks | |
| EE200100027A (et) | Fosfororgaanilised ühendid, neid sisaldav farmatseutiline preparaat ja nende kasutamine | |
| FI970095A0 (fi) | Uudet kemialliset yhdisteet, niiden valmistus ja niiden käyttö lääkeaineena | |
| EE200200022A (et) | Aminotiasooli derivaadid, nende valmistamine ja neid sisaldavad farmatseutilised kompositsioonid |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB4A | Valid patent at the end of a year |
Effective date: 20101231 |
|
| MM4A | Lapsed by not paying the annual fees |
Effective date: 20111117 |