EE03868B1 - Protsess O-(3-amino-2-hüdroksüpropüül) hüdroksüümhappehalogeniidide valmistamiseks - Google Patents

Protsess O-(3-amino-2-hüdroksüpropüül) hüdroksüümhappehalogeniidide valmistamiseks

Info

Publication number
EE03868B1
EE03868B1 EEP199900438A EE9900438A EE03868B1 EE 03868 B1 EE03868 B1 EE 03868B1 EE P199900438 A EEP199900438 A EE P199900438A EE 9900438 A EE9900438 A EE 9900438A EE 03868 B1 EE03868 B1 EE 03868B1
Authority
EE
Estonia
Prior art keywords
hydroxypropyl
amino
preparation
acid halides
hydroxymic acid
Prior art date
Application number
EEP199900438A
Other languages
English (en)
Estonian (et)
Other versions
EE9900438A (et
Inventor
�r�gdi L�szl�
Barab�s Mih�ly
M�rv�nyos Ede
T�r�k Magdolna
Cs�kai Zita
Original Assignee
Biorex Kutat� �S Fejleszt� Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biorex Kutat� �S Fejleszt� Rt. filed Critical Biorex Kutat� �S Fejleszt� Rt.
Publication of EE9900438A publication Critical patent/EE9900438A/xx
Publication of EE03868B1 publication Critical patent/EE03868B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/12—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reactions not involving the formation of oxyimino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/02—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by halogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
EEP199900438A 1997-04-03 1997-12-05 Protsess O-(3-amino-2-hüdroksüpropüül) hüdroksüümhappehalogeniidide valmistamiseks EE03868B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU9700699A HU220971B1 (hu) 1997-04-03 1997-04-03 Eljárás 0-(3-amino-2-hidroxi-propil)-hidroximsav-halogenidek előállítására
PCT/HU1997/000082 WO1998043948A1 (en) 1997-04-03 1997-12-05 Process for preparing o-(3-amino-2-hydroxy-propyl)-hydroxymic acid halides

Publications (2)

Publication Number Publication Date
EE9900438A EE9900438A (et) 2000-04-17
EE03868B1 true EE03868B1 (et) 2002-10-15

Family

ID=89994956

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900438A EE03868B1 (et) 1997-04-03 1997-12-05 Protsess O-(3-amino-2-hüdroksüpropüül) hüdroksüümhappehalogeniidide valmistamiseks

Country Status (33)

Country Link
US (1) US6180787B1 (no)
EP (1) EP0975585A1 (no)
JP (1) JP2001521498A (no)
KR (1) KR20010005943A (no)
CN (1) CN1251574A (no)
AP (1) AP9901646A0 (no)
AR (1) AR012308A1 (no)
AU (1) AU737994B2 (no)
BG (1) BG63116B1 (no)
BR (1) BR9714717A (no)
CA (1) CA2285360A1 (no)
CO (1) CO4940491A1 (no)
EA (1) EA199900899A1 (no)
EE (1) EE03868B1 (no)
EG (1) EG22104A (no)
HR (1) HRP980175A2 (no)
HU (1) HU220971B1 (no)
ID (1) ID20016A (no)
IL (1) IL132048A0 (no)
IS (1) IS5174A (no)
MA (1) MA26143A1 (no)
NO (1) NO312027B1 (no)
NZ (1) NZ500020A (no)
PE (1) PE83299A1 (no)
PL (1) PL336072A1 (no)
SK (1) SK134899A3 (no)
TN (1) TNSN98046A1 (no)
TR (1) TR199902207T2 (no)
TW (1) TW455573B (no)
UY (1) UY24945A1 (no)
WO (1) WO1998043948A1 (no)
YU (1) YU49499A (no)
ZA (1) ZA982755B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9900475D0 (en) * 1999-02-26 1999-04-28 Biorex Kutato Fejlesztoe Kft O-(3-piperidino-2-hydroxy-1-propyl)-hiyroximic acid-halogenid derivative, it's use for treating insulin resistance, and pharmaceutical compositions containing them as active component
WO2003057664A1 (en) 2002-01-11 2003-07-17 Biorex Kutató És Fejlesztö Rt. Carboxamidine derivatives and their use in the treatment of vascular diseases
HUP0303584A3 (en) 2003-10-30 2009-12-28 Cytrx Corp Use of a hydroximic acid halide derivative in the treatment of neurodegenerative diseases
CA2859469A1 (en) * 2011-12-23 2013-06-27 Akzo Nobel Chemicals International B.V. Chemical compounds
NZ700848A (en) * 2012-06-14 2016-08-26 Novartis Ag Azetidinium-containing copolymers and uses thereof
CN103804309B (zh) * 2012-11-09 2019-08-02 广州喜鹊医药有限公司 一种氯肟类化合物及其制备方法和在制药中的应用
MX2023005954A (es) 2020-11-19 2023-09-04 Zevra Denmark As Procesos para preparar citrato de arimoclomol e intermediarios del mismo.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU207305B (en) * 1988-03-23 1993-03-29 Chinoin Gyogyszer Es Vegyeszet Improved process for producing amidoxime derivatives
HU207988B (en) * 1988-10-20 1993-07-28 Biorex Kutato Fejlesztoe Kft Process for producing halogenides of o-/3-amino-2-hydroxy-propyl/hydroximic acid and pharmaceutical compositions containing them as active components
HUT54347A (en) * 1989-01-10 1991-02-28 Chinoin Gyogyszer Es Vegyeszet Improved process for producing amidoximes

Also Published As

Publication number Publication date
AR012308A1 (es) 2000-10-18
TW455573B (en) 2001-09-21
PE83299A1 (es) 1999-09-01
HRP980175A2 (en) 1999-06-30
AU737994B2 (en) 2001-09-06
HU220971B1 (hu) 2002-07-29
MA26143A1 (fr) 2004-07-01
NO994628L (no) 1999-09-23
YU49499A (sh) 2001-09-28
HUP9700699A2 (hu) 1999-01-28
BR9714717A (pt) 2000-06-20
TR199902207T2 (xx) 2000-02-21
WO1998043948A1 (en) 1998-10-08
BG63116B1 (bg) 2001-04-30
CA2285360A1 (en) 1998-10-08
BG103847A (en) 2000-07-31
TNSN98046A1 (fr) 2005-03-15
EG22104A (en) 2002-07-31
AP9901646A0 (en) 1999-09-30
HUP9700699A3 (en) 1999-04-28
KR20010005943A (ko) 2001-01-15
UY24945A1 (es) 1998-09-28
AU5405598A (en) 1998-10-22
CN1251574A (zh) 2000-04-26
SK134899A3 (en) 2000-06-12
NO312027B1 (no) 2002-03-04
IS5174A (is) 1999-09-10
EP0975585A1 (en) 2000-02-02
ZA982755B (en) 1998-10-01
NO994628D0 (no) 1999-09-23
JP2001521498A (ja) 2001-11-06
EA199900899A1 (ru) 2000-04-24
IL132048A0 (en) 2001-03-19
EE9900438A (et) 2000-04-17
ID20016A (id) 1998-09-10
CO4940491A1 (es) 2000-07-24
PL336072A1 (en) 2000-06-05
NZ500020A (en) 2001-09-28
US6180787B1 (en) 2001-01-30
HU9700699D0 (en) 1997-05-28

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20021231

MM4A Lapsed by not paying the annual fees

Effective date: 20021205