EE03377B1 - Farmatseutilised liposoomsüstepreparaadid - Google Patents

Farmatseutilised liposoomsüstepreparaadid

Info

Publication number
EE03377B1
EE03377B1 EE9500063A EE9500063A EE03377B1 EE 03377 B1 EE03377 B1 EE 03377B1 EE 9500063 A EE9500063 A EE 9500063A EE 9500063 A EE9500063 A EE 9500063A EE 03377 B1 EE03377 B1 EE 03377B1
Authority
EE
Estonia
Prior art keywords
phospholipid
pharmaceutical preparations
liposomal injection
cryoprotector
cooa
Prior art date
Application number
EE9500063A
Other languages
English (en)
Estonian (et)
Other versions
EE9500063A (et
Inventor
Hamann Hans-J�rgen
Serno Peter
Herboth Matthias
Kurka Peter
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of EE9500063A publication Critical patent/EE9500063A/xx
Publication of EE03377B1 publication Critical patent/EE03377B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906—Drug delivery
    • Y10S977/907—Liposome
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • External Artificial Organs (AREA)
  • Glass Compositions (AREA)
EE9500063A 1994-09-12 1995-09-11 Farmatseutilised liposoomsüstepreparaadid EE03377B1 (et)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4432378A DE4432378A1 (de) 1994-09-12 1994-09-12 Injizierbare liposomale Arzneizubereitungen

Publications (2)

Publication Number Publication Date
EE9500063A EE9500063A (et) 1996-04-15
EE03377B1 true EE03377B1 (et) 2001-04-16

Family

ID=6527981

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9500063A EE03377B1 (et) 1994-09-12 1995-09-11 Farmatseutilised liposoomsüstepreparaadid

Country Status (28)

Country Link
US (1) US5653998A (zh)
EP (1) EP0700679B1 (zh)
JP (1) JPH0881361A (zh)
KR (1) KR960009998A (zh)
CN (1) CN1079668C (zh)
AT (1) ATE187327T1 (zh)
AU (1) AU698441B2 (zh)
CA (1) CA2157849A1 (zh)
CZ (1) CZ287975B6 (zh)
DE (2) DE4432378A1 (zh)
DK (1) DK0700679T3 (zh)
EE (1) EE03377B1 (zh)
ES (1) ES2139800T3 (zh)
FI (1) FI954204A (zh)
GR (1) GR3032664T3 (zh)
HU (1) HUT73808A (zh)
IL (1) IL115222A (zh)
MY (1) MY111841A (zh)
NO (1) NO311556B1 (zh)
NZ (1) NZ272943A (zh)
PL (1) PL181541B1 (zh)
PT (1) PT700679E (zh)
RU (1) RU2160099C2 (zh)
SI (1) SI0700679T1 (zh)
SK (1) SK281611B6 (zh)
TW (1) TW359616B (zh)
UA (1) UA29469C2 (zh)
ZA (1) ZA957604B (zh)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458373B1 (en) * 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
DE19709704C2 (de) 1997-03-10 1999-11-04 Michael Georgieff Verwendung einer flüssigen Präparation von Xenon zur intravenösen Verabreichung bei Einleitung und/oder Aufrechterhaltung der Anaesthesie
US7030155B2 (en) 1998-06-05 2006-04-18 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
KR20000003433A (ko) * 1998-06-29 2000-01-15 김영환 반도체소자의 커패시터 제조방법
IL143104A (en) * 1998-11-13 2005-09-25 Optime Therapeutics Inc Method and apparatus for liposome production
JP2003508349A (ja) * 1999-05-14 2003-03-04 エスペリオン エルユーブイ ディベロップメント， インコーポレイテッド アンギナおよび／またはアンギナ等価状態を処置する方法、ならびにそれに関連する薬学的組成物およびキット
ES2272496T3 (es) 2000-02-04 2007-05-01 Lipoxen Technologies Limited Procedimiento de deshidratacion/rehidritacion para la preparacion de lipososmas.
US20060177416A1 (en) 2003-10-14 2006-08-10 Medivas, Llc Polymer particle delivery compositions and methods of use
DE60329497D1 (de) 2002-06-26 2009-11-12 Medigene Ag Herstellung einer kationisch liposomalen zubereitung, einen lipophilen wirkstoff enthaltend
DE10255195A1 (de) * 2002-11-27 2004-06-09 Lipoid Gmbh Micellare wasserlösliche Konzentrate
EP1643972A4 (en) * 2003-06-27 2010-01-20 Smithkline Beecham Corp STABILIZED LIPOSOMAL TOPOTECAN COMPOSITION AND METHOD
US7345093B2 (en) * 2004-04-27 2008-03-18 Formatech, Inc. Methods of enhancing solubility of compounds
EP1868571A4 (en) * 2005-03-02 2011-10-26 Univ Northeastern MITOCHONDRIOTROPIC PHOSPHOLIPIDE VESICLES
US20090220583A1 (en) * 2005-06-09 2009-09-03 Lena Pereswetoff-Morath Method and composition for treating inflammatory disorders
CA2623239C (en) 2005-09-22 2016-07-12 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
CA2623198C (en) 2005-09-22 2014-08-05 Medivas, Llc Bis-(a-amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
EP2034961A1 (de) * 2006-06-30 2009-03-18 Gertrud Langhoff Solubilisatformulierungen
WO2010107081A1 (ja) * 2009-03-19 2010-09-23 第一三共株式会社 包装により安定保存された固形製剤
US20110070294A1 (en) * 2009-09-23 2011-03-24 Javeri Indu Methods for the Administration of Drugs Using Liposomes
US10143652B2 (en) 2009-09-23 2018-12-04 Curirx Inc. Methods for the preparation of liposomes
EP2480208A1 (en) * 2009-09-23 2012-08-01 Indu Javeri Methods for the preparation of liposomes
IT1404011B1 (it) 2010-12-03 2013-11-08 Uni Degli Studi Magna Graecia Di Catanzaro Nanovettore coniugato con tsh per il trattamento del cancro della tiroide
PL226015B1 (pl) * 2011-03-03 2017-06-30 Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną Liposomowy preparat zawierajacy przeciwnowotworowa substancje aktywna, sposob jego wytwarzania i zawierajaca go kompozycja farmaceutyczna
EP2723800B1 (en) 2011-06-23 2015-10-07 DSM IP Assets B.V. Micro- or nanoparticles comprising a biodegradable polyesteramide copolymer for use in the delivery of bioactive agents
US9873765B2 (en) 2011-06-23 2018-01-23 Dsm Ip Assets, B.V. Biodegradable polyesteramide copolymers for drug delivery
FR2979239A1 (fr) * 2011-08-25 2013-03-01 Trophos Liposome comprenant au moins un derive de cholesterol
EP2682106A1 (en) 2012-07-03 2014-01-08 Phares Pharmaceutical Research N.V. Method of solubilizing biologically active compounds
WO2014085914A1 (en) * 2012-12-06 2014-06-12 Misudan Enterprises Inc. Topical liposome compositions containing phenolic anti-inflammatory agents and their methods of preparation
AU2015366355B2 (en) 2014-12-18 2020-05-28 Dsm Ip Assets B.V. Drug delivery system for delivery of acid sensitive drugs
CN110898011B (zh) * 2019-11-27 2022-02-08 西南医科大学 一种依托咪酯纳米制剂及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3515335C2 (de) * 1985-04-27 1995-01-26 Bayer Ag Arzneizubereitung enthaltend Dihydropyridine und Verfahren zu ihrer Herstellung
DE4117750A1 (de) * 1991-05-30 1992-12-24 Bayer Ag Neue 2-amino-5-cyano-1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE4207481A1 (de) * 1992-03-10 1993-09-16 Bayer Ag Liposomale wirkstoff-formulierungen und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
EE9500063A (et) 1996-04-15
AU3046495A (en) 1996-03-28
CZ234195A3 (en) 1996-03-13
CZ287975B6 (cs) 2001-03-14
SK281611B6 (sk) 2001-05-10
PL181541B1 (pl) 2001-08-31
KR960009998A (ko) 1996-04-20
EP0700679B1 (de) 1999-12-08
GR3032664T3 (en) 2000-06-30
DE4432378A1 (de) 1996-03-14
NO953578D0 (no) 1995-09-11
PL310344A1 (en) 1996-03-18
TW359616B (en) 1999-06-01
HUT73808A (en) 1996-09-30
NO953578L (no) 1996-03-13
MY111841A (en) 2001-01-31
FI954204A (fi) 1996-03-13
EP0700679A1 (de) 1996-03-13
IL115222A (en) 1999-06-20
FI954204A0 (fi) 1995-09-08
DK0700679T3 (da) 2000-05-29
US5653998A (en) 1997-08-05
HU9502654D0 (en) 1995-11-28
ZA957604B (en) 1996-04-15
SI0700679T1 (en) 2000-02-29
NZ272943A (en) 1996-07-26
ATE187327T1 (de) 1999-12-15
ES2139800T3 (es) 2000-02-16
DE59507372D1 (de) 2000-01-13
AU698441B2 (en) 1998-10-29
CA2157849A1 (en) 1996-03-13
SK112795A3 (en) 1997-02-05
NO311556B1 (no) 2001-12-10
CN1079668C (zh) 2002-02-27
UA29469C2 (uk) 2000-11-15
JPH0881361A (ja) 1996-03-26
PT700679E (pt) 2000-05-31
RU2160099C2 (ru) 2000-12-10
IL115222A0 (en) 1995-12-31
CN1128655A (zh) 1996-08-14

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20021231

MM4A Lapsed by not paying the annual fees

Effective date: 20020911