EE03053B1 - Medetomidiin ja tema optiliselt aktiivsete enantiomeeride soolad ravimite transdermaalse manustamise kiiruse reguleerimiseks - Google Patents

Medetomidiin ja tema optiliselt aktiivsete enantiomeeride soolad ravimite transdermaalse manustamise kiiruse reguleerimiseks

Info

Publication number
EE03053B1
EE03053B1 EE9400270A EE9400270A EE03053B1 EE 03053 B1 EE03053 B1 EE 03053B1 EE 9400270 A EE9400270 A EE 9400270A EE 9400270 A EE9400270 A EE 9400270A EE 03053 B1 EE03053 B1 EE 03053B1
Authority
EE
Estonia
Prior art keywords
medetomidine
rate
optically active
control
drug delivery
Prior art date
Application number
EE9400270A
Other languages
English (en)
Estonian (et)
Inventor
G�sta Jalonen Harry
Johannes Karjalainen Arto
Original Assignee
Orion-Yhtym Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion-Yhtym Oy filed Critical Orion-Yhtym Oy
Publication of EE03053B1 publication Critical patent/EE03053B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EE9400270A 1991-05-31 1994-10-18 Medetomidiin ja tema optiliselt aktiivsete enantiomeeride soolad ravimite transdermaalse manustamise kiiruse reguleerimiseks EE03053B1 (et)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919111732A GB9111732D0 (en) 1991-05-31 1991-05-31 The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs

Publications (1)

Publication Number Publication Date
EE03053B1 true EE03053B1 (et) 1997-12-15

Family

ID=10695876

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9400270A EE03053B1 (et) 1991-05-31 1994-10-18 Medetomidiin ja tema optiliselt aktiivsete enantiomeeride soolad ravimite transdermaalse manustamise kiiruse reguleerimiseks

Country Status (17)

Country Link
US (1) US5438067A (xx)
EP (1) EP0587819B1 (xx)
JP (2) JP3483881B2 (xx)
AT (1) ATE149090T1 (xx)
AU (1) AU1798192A (xx)
CA (1) CA2110161C (xx)
DE (1) DE69217658T2 (xx)
EE (1) EE03053B1 (xx)
FI (1) FI104948B (xx)
GB (2) GB9111732D0 (xx)
IE (1) IE67168B1 (xx)
LT (1) LT3130B (xx)
LV (1) LV10047B (xx)
NO (1) NO303818B1 (xx)
NZ (1) NZ242717A (xx)
WO (1) WO1992021338A1 (xx)
ZA (1) ZA923395B (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883115A (en) * 1992-11-09 1999-03-16 Pharmetrix Division Technical Chemicals & Products, Inc. Transdermal delivery of the eutomer of a chiral drug
GB2290964A (en) * 1994-07-08 1996-01-17 Arto Olavi Urtti Transdermal drug delivery system
GB9521680D0 (en) * 1995-10-23 1996-01-03 Orion Yhtymo Oy New use of imidazole derivatives
US5730721A (en) 1996-01-25 1998-03-24 Vesture Corporation Medical applicator and method
GB9614098D0 (en) 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan
IT1290255B1 (it) * 1997-02-05 1998-10-22 Wallcovering Pubblicita S R L Supporto sagomato aderente all'epidermide per la cessione di sostanze cosmetiche o farmacologiche e metodo per la sua fabbricazione
DE19936395C2 (de) 1999-08-03 2002-07-18 Antonia Buntz Kosmetikpflaster und Verfahren zum Anheben der weiblichen Brust mittels eines solchen Kosmetikpflasters und seine Verwendung
US6682757B1 (en) 2000-11-16 2004-01-27 Euro-Celtique, S.A. Titratable dosage transdermal delivery system
US7795263B2 (en) * 2008-07-08 2010-09-14 Wildlife Laboratories, Inc. Pharmaceutical combination for and method of anesthetizing and immobilizing non-domesticated mammals
CN106511273A (zh) * 2009-05-15 2017-03-22 瑞克欧制药有限公司 舌下右美托咪定组合物及其使用方法
CA2786598A1 (en) * 2010-01-08 2011-07-14 Recro Pharma, Inc. Topical transdermal dexmedetomidine compositions and methods of use thereof
US20120202863A1 (en) * 2011-02-03 2012-08-09 Gerald Horn Compositions and methods for treatment of glaucoma
WO2013090278A2 (en) 2011-12-11 2013-06-20 Recro Pharma, Inc. Intranasal dexmedetomidine compositions and methods of use thereof
KR101827980B1 (ko) * 2013-10-07 2018-02-13 테이코쿠 팔마 유에스에이, 인코포레이티드 덱스메데토미딘 경피 전달 장치 및 이의 사용 방법
KR101831290B1 (ko) * 2013-10-07 2018-02-22 테이코쿠 팔마 유에스에이, 인코포레이티드 덱스메데토미딘 경피 조성물을 사용하여 주의력 결핍 과잉행동 장애, 불안 및 불면증을 치료하기 위한 방법 및 조성물
KR101881791B1 (ko) * 2013-10-07 2018-07-25 테이코쿠 팔마 유에스에이, 인코포레이티드 비진정성 덱스메데토미딘 경피 조성물을 사용하여 금단 증후군을 치료하기 위한 방법 및 조성물
JP6188934B2 (ja) * 2013-10-07 2017-08-30 テイコク ファーマ ユーエスエー インコーポレーテッド デクスメデトミジン経皮組成物を含む疼痛管理用方法及び組成物
ES2847936T3 (es) 2013-10-07 2021-08-04 Teikoku Pharma Usa Inc Métodos y composiciones para el suministro transdérmico de una cantidad no sedante de dexmedetomidina
JP6469587B2 (ja) 2013-12-18 2019-02-13 丸石製薬株式会社 含水型貼付剤
CN111346072B (zh) * 2018-12-21 2022-05-27 宜昌人福药业有限责任公司 一种透皮给药的药物组合物及其制备方法
US20220211672A1 (en) 2019-05-01 2022-07-07 Clexio Biosciences Ltd. Methods of treating pruritus
BR112021020962A2 (pt) 2019-05-01 2021-12-14 Clexio Biosciences Ltd Métodos de tratamento de prurido
TWI772807B (zh) 2019-05-27 2022-08-01 日商救急藥品工業股份有限公司 外用製劑

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
FI864570A0 (fi) * 1986-11-11 1986-11-11 Farmos Oy Terapeutiskt anvaendbar foerening.
GB2206880B (en) * 1987-07-16 1991-04-24 Farmos Oy Optical isomers of an imidazole derivative
GB2215206B (en) * 1988-02-29 1991-07-03 Farmos Oy 4-substituted imidazole derivatives useful in perioperative care
US5217718A (en) * 1989-08-18 1993-06-08 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
US5124157A (en) * 1989-08-18 1992-06-23 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
US5304569A (en) * 1989-11-13 1994-04-19 Orion-Yhtyma Oy Compositions and their use in lowering intraocular pressure

Also Published As

Publication number Publication date
NO934323D0 (no) 1993-11-29
GB2256367B (en) 1995-03-15
FI935351A (fi) 1993-11-30
NZ242717A (en) 1994-03-25
DE69217658D1 (de) 1997-04-03
GB9211033D0 (en) 1992-07-08
IE921937A1 (en) 1992-12-02
ATE149090T1 (de) 1997-03-15
FI104948B (fi) 2000-05-15
CA2110161C (en) 2004-08-03
CA2110161A1 (en) 1992-12-10
ZA923395B (en) 1993-03-31
US5438067A (en) 1995-08-01
EP0587819B1 (en) 1997-02-26
LV10047B (en) 1995-02-20
IE67168B1 (en) 1996-03-06
LT3130B (en) 1994-12-25
JPH06507888A (ja) 1994-09-08
GB9111732D0 (en) 1991-07-24
EP0587819A1 (en) 1994-03-23
LTIP112A (en) 1994-07-15
NO934323L (no) 1993-11-29
FI935351A0 (fi) 1993-11-30
AU1798192A (en) 1993-01-08
DE69217658T2 (de) 1997-07-03
GB2256367A (en) 1992-12-09
LV10047A (lv) 1994-05-10
JP3483881B2 (ja) 2004-01-06
JP2003327531A (ja) 2003-11-19
WO1992021338A1 (en) 1992-12-10
NO303818B1 (no) 1998-09-07

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20021231

KB4A Valid patent at the end of a year

Effective date: 20031231

KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

MM4A Lapsed by not paying the annual fees

Effective date: 20051018