ECSP10010597A - Nueva clase de espiro piperidinas para el tratamiento de enfermedades neurodegenerativas - Google Patents
Nueva clase de espiro piperidinas para el tratamiento de enfermedades neurodegenerativasInfo
- Publication number
- ECSP10010597A ECSP10010597A EC2010010597A ECSP10010597A ECSP10010597A EC SP10010597 A ECSP10010597 A EC SP10010597A EC 2010010597 A EC2010010597 A EC 2010010597A EC SP10010597 A ECSP10010597 A EC SP10010597A EC SP10010597 A ECSP10010597 A EC SP10010597A
- Authority
- EC
- Ecuador
- Prior art keywords
- treatment
- espiro
- piperidines
- neurodegenerative diseases
- new class
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5042308P | 2008-05-05 | 2008-05-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP10010597A true ECSP10010597A (es) | 2010-12-30 |
Family
ID=40902870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2010010597A ECSP10010597A (es) | 2008-05-05 | 2010-11-09 | Nueva clase de espiro piperidinas para el tratamiento de enfermedades neurodegenerativas |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20110046160A1 (enExample) |
| EP (1) | EP2300484B1 (enExample) |
| JP (1) | JP2011519913A (enExample) |
| KR (1) | KR20110000749A (enExample) |
| CN (1) | CN102083841A (enExample) |
| AP (1) | AP2010005456A0 (enExample) |
| AT (1) | ATE537178T1 (enExample) |
| AU (1) | AU2009245322B2 (enExample) |
| BR (1) | BRPI0912433A2 (enExample) |
| CA (1) | CA2721786A1 (enExample) |
| CO (1) | CO6321280A2 (enExample) |
| CR (1) | CR11759A (enExample) |
| DO (1) | DOP2010000317A (enExample) |
| EA (1) | EA201001566A1 (enExample) |
| EC (1) | ECSP10010597A (enExample) |
| ES (1) | ES2375913T3 (enExample) |
| IL (1) | IL208793A0 (enExample) |
| MA (1) | MA32290B1 (enExample) |
| MX (1) | MX2010012066A (enExample) |
| NZ (1) | NZ588589A (enExample) |
| SV (1) | SV2010003725A (enExample) |
| WO (1) | WO2009136350A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7763609B2 (en) | 2003-12-15 | 2010-07-27 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
| UA108363C2 (uk) | 2009-10-08 | 2015-04-27 | Похідні імінотіадіазиндіоксиду як інгібітори bace, композиція на їх основі і їх застосування | |
| WO2011125006A2 (en) * | 2010-04-09 | 2011-10-13 | Pfizer Inc. | Novel sultam compounds |
| EP2694521B1 (en) | 2011-04-07 | 2015-11-25 | Merck Sharp & Dohme Corp. | Pyrrolidine-fused thiadiazine dioxide compounds as bace inhibitors, compositions, and their use |
| EP2694489B1 (en) | 2011-04-07 | 2017-09-06 | Merck Sharp & Dohme Corp. | C5-c6 oxacyclic-fused thiadiazine dioxide compounds as bace inhibitors, compositions, and their use |
| JP2014524472A (ja) | 2011-08-22 | 2014-09-22 | メルク・シャープ・アンド・ドーム・コーポレーション | Ｂａｃｅ阻害剤としての２−スピロ置換イミノチアジンならびにそのモノオキシドおよびジオキシド、組成物、ならびにそれらの使用 |
| EP3233799B1 (en) | 2014-12-19 | 2021-05-19 | The Broad Institute, Inc. | Dopamine d2 receptor ligands |
| US10633336B2 (en) | 2014-12-19 | 2020-04-28 | The Broad Institute, Inc. | Dopamine D2 receptor ligands |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100413865C (zh) * | 2004-01-08 | 2008-08-27 | 弗·哈夫曼-拉罗切有限公司 | 二氮杂-螺哌啶衍生物 |
| JP2006044497A (ja) * | 2004-08-05 | 2006-02-16 | Toyota Motor Corp | 車輪情報処理装置 |
| AU2005295814A1 (en) * | 2004-10-13 | 2006-04-27 | Merck & Co., Inc. | Spiropiperidine compounds useful as beta-secretase inhibitors for the treatment of Alzhermer's disease |
| WO2007011833A2 (en) * | 2005-07-18 | 2007-01-25 | Merck & Co., Inc. | Spiropiperidine beta-secretase inhibitors for the treatment of alzheimer's disease |
| JP2010502705A (ja) * | 2006-09-07 | 2010-01-28 | メルク エンド カムパニー インコーポレーテッド | アルツハイマー病の治療用としてのスピロピペリジンベータセクレターゼ阻害剤 |
| US8377954B2 (en) * | 2007-01-04 | 2013-02-19 | Merck, Sharp & Dohme, Corp | Bicyclic spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's disease |
-
2009
- 2009-05-04 EA EA201001566A patent/EA201001566A1/ru unknown
- 2009-05-04 AT AT09742523T patent/ATE537178T1/de active
- 2009-05-04 ES ES09742523T patent/ES2375913T3/es active Active
- 2009-05-04 EP EP09742523A patent/EP2300484B1/en active Active
- 2009-05-04 WO PCT/IB2009/051815 patent/WO2009136350A1/en not_active Ceased
- 2009-05-04 CN CN2009801261947A patent/CN102083841A/zh active Pending
- 2009-05-04 KR KR1020107024794A patent/KR20110000749A/ko not_active Ceased
- 2009-05-04 NZ NZ588589A patent/NZ588589A/en not_active IP Right Cessation
- 2009-05-04 AP AP2010005456A patent/AP2010005456A0/xx unknown
- 2009-05-04 MX MX2010012066A patent/MX2010012066A/es not_active Application Discontinuation
- 2009-05-04 JP JP2011508035A patent/JP2011519913A/ja not_active Withdrawn
- 2009-05-04 US US12/990,739 patent/US20110046160A1/en not_active Abandoned
- 2009-05-04 BR BRPI0912433A patent/BRPI0912433A2/pt not_active Application Discontinuation
- 2009-05-04 CA CA2721786A patent/CA2721786A1/en not_active Abandoned
- 2009-05-04 AU AU2009245322A patent/AU2009245322B2/en not_active Ceased
-
2010
- 2010-10-18 IL IL208793A patent/IL208793A0/en unknown
- 2010-10-21 DO DO2010000317A patent/DOP2010000317A/es unknown
- 2010-10-26 CR CR11759A patent/CR11759A/es not_active Application Discontinuation
- 2010-11-05 SV SV2010003725A patent/SV2010003725A/es not_active Application Discontinuation
- 2010-11-05 MA MA33328A patent/MA32290B1/fr unknown
- 2010-11-09 EC EC2010010597A patent/ECSP10010597A/es unknown
- 2010-11-11 CO CO10141834A patent/CO6321280A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CO6321280A2 (es) | 2011-09-20 |
| ATE537178T1 (de) | 2011-12-15 |
| SV2010003725A (es) | 2011-07-05 |
| JP2011519913A (ja) | 2011-07-14 |
| MX2010012066A (es) | 2010-12-06 |
| AU2009245322A1 (en) | 2009-11-12 |
| AU2009245322B2 (en) | 2011-07-14 |
| AP2010005456A0 (en) | 2010-12-31 |
| BRPI0912433A2 (pt) | 2015-12-22 |
| EA201001566A1 (ru) | 2011-04-29 |
| KR20110000749A (ko) | 2011-01-05 |
| ES2375913T3 (es) | 2012-03-07 |
| MA32290B1 (fr) | 2011-05-02 |
| EP2300484B1 (en) | 2011-12-14 |
| US20110046160A1 (en) | 2011-02-24 |
| CA2721786A1 (en) | 2009-11-12 |
| IL208793A0 (en) | 2010-12-30 |
| EP2300484A1 (en) | 2011-03-30 |
| DOP2010000317A (es) | 2010-11-15 |
| WO2009136350A1 (en) | 2009-11-12 |
| CR11759A (es) | 2010-11-22 |
| CN102083841A (zh) | 2011-06-01 |
| NZ588589A (en) | 2012-07-27 |
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