ECSP099630A - Proceso e intermediarios para preparar arzoxifeno - Google Patents

Proceso e intermediarios para preparar arzoxifeno

Info

Publication number
ECSP099630A
ECSP099630A EC2009009630A ECSP099630A ECSP099630A EC SP099630 A ECSP099630 A EC SP099630A EC 2009009630 A EC2009009630 A EC 2009009630A EC SP099630 A ECSP099630 A EC SP099630A EC SP099630 A ECSP099630 A EC SP099630A
Authority
EC
Ecuador
Prior art keywords
prepare
arzoxifen
intermediaries
arzoxifene
ch2ch3
Prior art date
Application number
EC2009009630A
Other languages
English (en)
Inventor
Charles Arthur Alt
Douglas Patton Kjell
Tony Yantao Zhang
Jared Wade Fennell
Fu-Yao Zhang
Kevin Dale Seibert
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39535578&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP099630(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ECSP099630A publication Critical patent/ECSP099630A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención proporciona nuevos compuestos de la fórmula I: (I)en donde X es S o S(O); R1 y R2 se seleccionan cada uno independientemente del grupo que consiste de CH2CH3 y fenilo; o R1 y R2 se combinan para formar morfolino y con procesos para preparar arzoxifeno.
EC2009009630A 2007-03-16 2009-09-14 Proceso e intermediarios para preparar arzoxifeno ECSP099630A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89515407P 2007-03-16 2007-03-16

Publications (1)

Publication Number Publication Date
ECSP099630A true ECSP099630A (es) 2009-10-30

Family

ID=39535578

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2009009630A ECSP099630A (es) 2007-03-16 2009-09-14 Proceso e intermediarios para preparar arzoxifeno

Country Status (19)

Country Link
US (1) US8124776B2 (es)
EP (1) EP2125774A1 (es)
JP (1) JP2010521475A (es)
KR (1) KR20090112758A (es)
AR (1) AR065770A1 (es)
AU (1) AU2008229183A1 (es)
BR (1) BRPI0808740A2 (es)
CA (1) CA2681478A1 (es)
CL (1) CL2008000753A1 (es)
CR (1) CR10970A (es)
DO (1) DOP2009000218A (es)
EA (1) EA200970863A1 (es)
EC (1) ECSP099630A (es)
IL (1) IL199785A0 (es)
MX (1) MX2009009858A (es)
PE (1) PE20081886A1 (es)
TN (1) TN2009000372A1 (es)
TW (1) TW200902521A (es)
WO (1) WO2008115686A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3360870A1 (en) 2013-02-19 2018-08-15 Novartis AG Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE44597A1 (es) 1995-02-28 1997-10-13 Lilly Co Eli Compuestos de benzotiofeno, productos intermedios, composiciones y procedimientos
US5939439A (en) * 1996-12-30 1999-08-17 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
ZA982877B (en) * 1997-04-09 1999-10-04 Lilly Co Eli Treatment of central nervous system disorders with selective estrogen receptor modulators.

Also Published As

Publication number Publication date
BRPI0808740A2 (pt) 2014-08-12
IL199785A0 (en) 2010-04-15
KR20090112758A (ko) 2009-10-28
TW200902521A (en) 2009-01-16
PE20081886A1 (es) 2008-12-27
AR065770A1 (es) 2009-07-01
JP2010521475A (ja) 2010-06-24
US8124776B2 (en) 2012-02-28
DOP2009000218A (es) 2009-09-30
EP2125774A1 (en) 2009-12-02
MX2009009858A (es) 2009-10-20
TN2009000372A1 (en) 2010-12-31
CR10970A (es) 2009-11-02
WO2008115686A1 (en) 2008-09-25
EA200970863A1 (ru) 2010-02-26
US20100137602A1 (en) 2010-06-03
AU2008229183A1 (en) 2008-09-25
CA2681478A1 (en) 2008-09-25
CL2008000753A1 (es) 2008-09-26

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