DOP2009000218A - Proceso e intermediarios para preparar arzoxifeno - Google Patents

Proceso e intermediarios para preparar arzoxifeno

Info

Publication number
DOP2009000218A
DOP2009000218A DO2009000218A DO2009000218A DOP2009000218A DO P2009000218 A DOP2009000218 A DO P2009000218A DO 2009000218 A DO2009000218 A DO 2009000218A DO 2009000218 A DO2009000218 A DO 2009000218A DO P2009000218 A DOP2009000218 A DO P2009000218A
Authority
DO
Dominican Republic
Prior art keywords
prepare
arzoxifen
intermediaries
arzoxifene
ch2ch3
Prior art date
Application number
DO2009000218A
Other languages
English (en)
Inventor
Charles Arthur Alt
Jared Wade Fennell
Douglas Patton Kjell
Fu-Yao Zhang
Tony Yantao Zhang
Kevin Dale Seibert
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39535578&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DOP2009000218(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DOP2009000218A publication Critical patent/DOP2009000218A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La presente invención proporciona nuevos compuestos de la formula I. En donde X es S o S(O). R1 y R2 se seleccionan cada uno independientemente del grupo que consiste de -CH2CH3 y fenilo. O R1 y R2 se combinan para formar morfolino y con procesos para preparar arzoxifeno.
DO2009000218A 2007-03-16 2009-09-15 Proceso e intermediarios para preparar arzoxifeno DOP2009000218A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89515407P 2007-03-16 2007-03-16

Publications (1)

Publication Number Publication Date
DOP2009000218A true DOP2009000218A (es) 2009-09-30

Family

ID=39535578

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2009000218A DOP2009000218A (es) 2007-03-16 2009-09-15 Proceso e intermediarios para preparar arzoxifeno

Country Status (19)

Country Link
US (1) US8124776B2 (es)
EP (1) EP2125774A1 (es)
JP (1) JP2010521475A (es)
KR (1) KR20090112758A (es)
AR (1) AR065770A1 (es)
AU (1) AU2008229183A1 (es)
BR (1) BRPI0808740A2 (es)
CA (1) CA2681478A1 (es)
CL (1) CL2008000753A1 (es)
CR (1) CR10970A (es)
DO (1) DOP2009000218A (es)
EA (1) EA200970863A1 (es)
EC (1) ECSP099630A (es)
IL (1) IL199785A0 (es)
MX (1) MX2009009858A (es)
PE (1) PE20081886A1 (es)
TN (1) TN2009000372A1 (es)
TW (1) TW200902521A (es)
WO (1) WO2008115686A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR201806882T4 (tr) 2013-02-19 2018-06-21 Novartis Ag Selektif östrojen reseptörü yıkıcıları olarak benzotiofen türevleri ve bunların bileşimleri.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL132954A (en) * 1995-02-28 2002-02-10 Lilly Co Eli Derivatives of benzothiophene
US5939439A (en) * 1996-12-30 1999-08-17 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
ZA982877B (en) 1997-04-09 1999-10-04 Lilly Co Eli Treatment of central nervous system disorders with selective estrogen receptor modulators.

Also Published As

Publication number Publication date
US20100137602A1 (en) 2010-06-03
WO2008115686A1 (en) 2008-09-25
TN2009000372A1 (en) 2010-12-31
ECSP099630A (es) 2009-10-30
CA2681478A1 (en) 2008-09-25
JP2010521475A (ja) 2010-06-24
US8124776B2 (en) 2012-02-28
AR065770A1 (es) 2009-07-01
KR20090112758A (ko) 2009-10-28
AU2008229183A1 (en) 2008-09-25
IL199785A0 (en) 2010-04-15
BRPI0808740A2 (pt) 2014-08-12
CR10970A (es) 2009-11-02
EA200970863A1 (ru) 2010-02-26
MX2009009858A (es) 2009-10-20
EP2125774A1 (en) 2009-12-02
TW200902521A (en) 2009-01-16
PE20081886A1 (es) 2008-12-27
CL2008000753A1 (es) 2008-09-26

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