ECSP088688A - Piperidinoilpirrolidinas agonistas del receptor de melanocortina tipo 4 - Google Patents

Piperidinoilpirrolidinas agonistas del receptor de melanocortina tipo 4

Info

Publication number
ECSP088688A
ECSP088688A EC2008008688A ECSP088688A ECSP088688A EC SP088688 A ECSP088688 A EC SP088688A EC 2008008688 A EC2008008688 A EC 2008008688A EC SP088688 A ECSP088688 A EC SP088688A EC SP088688 A ECSP088688 A EC SP088688A
Authority
EC
Ecuador
Prior art keywords
piperidinoilpirrolidinas
melanocortina
agonistas
receiver
type
Prior art date
Application number
EC2008008688A
Other languages
English (en)
Inventor
Alan Daniel Brown
Mark Lansdell
Mark David Andrews
Nicholas William Summerhill
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of ECSP088688A publication Critical patent/ECSP088688A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a una clase de agonistas de MCR4 de melanocortina de fórmula general (I) en la que las variables y sustituyentes son como se definen en este documento y especialmente a compuestos agonistas de MCR4 selectiva, a su uso en medicina, particularmente en el tratamiento de disfunción sexual y obesidad, a productos intermedios útiles en su síntesis y a composiciones que los contienen.
EC2008008688A 2006-02-23 2008-08-21 Piperidinoilpirrolidinas agonistas del receptor de melanocortina tipo 4 ECSP088688A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77629506P 2006-02-23 2006-02-23
US88784007P 2007-02-02 2007-02-02

Publications (1)

Publication Number Publication Date
ECSP088688A true ECSP088688A (es) 2008-10-31

Family

ID=38169450

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2008008688A ECSP088688A (es) 2006-02-23 2008-08-21 Piperidinoilpirrolidinas agonistas del receptor de melanocortina tipo 4

Country Status (21)

Country Link
US (1) US8138188B2 (es)
EP (1) EP1989196B1 (es)
KR (1) KR101036981B1 (es)
AP (1) AP2008004602A0 (es)
AU (1) AU2007219236B2 (es)
BR (1) BRPI0708264A2 (es)
CA (1) CA2642922C (es)
CR (1) CR10219A (es)
DK (1) DK1989196T3 (es)
EA (1) EA200801738A1 (es)
EC (1) ECSP088688A (es)
ES (1) ES2402581T3 (es)
IL (1) IL193279A (es)
MA (1) MA30228B1 (es)
ME (1) MEP6808A (es)
MX (1) MX2008010899A (es)
NO (1) NO20083480L (es)
RS (1) RS20080371A (es)
SG (1) SG185849A1 (es)
TN (1) TNSN08337A1 (es)
WO (1) WO2007096763A2 (es)

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US8828994B2 (en) 2011-03-08 2014-09-09 Sanofi Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
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PT4161927T (pt) 2020-06-09 2024-10-08 Pfizer Compostos de espiro como antagonistas do recetor de melanocortina 4 e utilizações dos mesmos
CA3241470A1 (en) 2021-12-06 2023-06-15 Pfizer Inc. Melanocortin 4 receptor antagonists and uses thereof
WO2025228895A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Hetaryl substituted indazoles and benzimidazoles as sting antagonists and the use thereof as medicament
WO2025228889A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Monoarylic heterocyclic compounds as sting antagonists and the use thereof as medicament
WO2025228900A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Arylamide substituted indazoles and the use thereof as medicament
WO2025228902A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Heterocyclic acids as sting antagonists and the use thereof as medicament
US20250333398A1 (en) 2024-04-30 2025-10-30 Boehringer Ingelheim International Gmbh Monoaryl and hetaryl substituted indazoles and benzimidazoles as sting antagonists and the use thereof as medicament
WO2025228899A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Further heterocyclic compounds as sting antagonists and the use thereof as medicament

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Also Published As

Publication number Publication date
NO20083480L (no) 2008-09-10
ES2402581T3 (es) 2013-05-06
KR20080095918A (ko) 2008-10-29
KR101036981B1 (ko) 2011-05-25
DK1989196T3 (da) 2013-04-15
EP1989196A2 (en) 2008-11-12
IL193279A0 (en) 2009-02-11
CA2642922C (en) 2011-08-02
IL193279A (en) 2012-12-31
RS20080371A (sr) 2009-07-15
MX2008010899A (es) 2008-11-27
WO2007096763A2 (en) 2007-08-30
WO2007096763A3 (en) 2007-10-18
HK1126489A1 (en) 2009-09-04
EP1989196B1 (en) 2013-02-13
EA200801738A1 (ru) 2008-12-30
US8138188B2 (en) 2012-03-20
MA30228B1 (fr) 2009-02-02
CR10219A (es) 2008-09-23
AU2007219236A1 (en) 2007-08-30
AP2008004602A0 (en) 2008-10-31
TNSN08337A1 (fr) 2009-12-29
AU2007219236B2 (en) 2012-06-21
BRPI0708264A2 (pt) 2011-05-24
SG185849A1 (en) 2012-12-28
MEP6808A (xx) 2010-02-10
CA2642922A1 (en) 2007-08-30
US20090036459A1 (en) 2009-02-05

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