GT200500118A - Nuevos derivados de indazol e indolona y su uso como productos farmaceuticos - Google Patents

Nuevos derivados de indazol e indolona y su uso como productos farmaceuticos

Info

Publication number
GT200500118A
GT200500118A GT200500118A GT200500118A GT200500118A GT 200500118 A GT200500118 A GT 200500118A GT 200500118 A GT200500118 A GT 200500118A GT 200500118 A GT200500118 A GT 200500118A GT 200500118 A GT200500118 A GT 200500118A
Authority
GT
Guatemala
Prior art keywords
indolona
indazol
pharmaceutical products
new derivatives
compounds
Prior art date
Application number
GT200500118A
Other languages
English (en)
Inventor
Charlotte Moira Norfor Allerton
David Hepworth
Duncan Charles Miller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0411810A external-priority patent/GB0411810D0/en
Priority claimed from GB0415455A external-priority patent/GB0415455D0/en
Application filed filed Critical
Publication of GT200500118A publication Critical patent/GT200500118A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A COMPUESTOS DE LA FORMULA GENERAL I EN LA QUE A,X,R1, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS SON AGONISTAS DE DOPAMINA Y MAS PARTICULARMENTE UNA CLASE DE AGONISTAS QUE SON SELECTIVOS POR D3 FRENTE A D2 POR LO QUE SON DE UTILIDAD EN PATOLOGIAS DE DISFUNCION SEXUAL TAL COMO LA FEMENINA ASI COMO LA MASCULINA.
GT200500118A 2004-05-26 2005-05-20 Nuevos derivados de indazol e indolona y su uso como productos farmaceuticos GT200500118A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0411810A GB0411810D0 (en) 2004-05-26 2004-05-26 New indazole and indolone derivatives and their use as pharmaceuticals
GB0415455A GB0415455D0 (en) 2004-07-09 2004-07-09 New indazole and indolone derivatives and their use as pharmaceuticals

Publications (1)

Publication Number Publication Date
GT200500118A true GT200500118A (es) 2006-01-10

Family

ID=35219654

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200500118A GT200500118A (es) 2004-05-26 2005-05-20 Nuevos derivados de indazol e indolona y su uso como productos farmaceuticos

Country Status (25)

Country Link
EP (1) EP1753763B1 (es)
JP (2) JP4093588B2 (es)
AP (1) AP2006003823A0 (es)
AR (1) AR049191A1 (es)
AT (1) ATE404560T1 (es)
AU (1) AU2005247696A1 (es)
BR (1) BRPI0511533A (es)
CA (1) CA2568050A1 (es)
CR (1) CR8772A (es)
DE (1) DE602005008954D1 (es)
EA (1) EA200601985A1 (es)
EC (1) ECSP067024A (es)
ES (1) ES2308492T3 (es)
GT (1) GT200500118A (es)
IL (1) IL179365A0 (es)
MA (1) MA28606B1 (es)
MX (1) MXPA06013759A (es)
NL (1) NL1029128C2 (es)
NO (1) NO20065328L (es)
PA (1) PA8635001A1 (es)
PE (1) PE20060289A1 (es)
SV (1) SV2005002128A (es)
TW (1) TW200607500A (es)
UY (1) UY28918A1 (es)
WO (1) WO2005116027A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR078411A1 (es) 2009-05-07 2011-11-09 Lilly Co Eli Compuesto de vinil imidazolilo y composicion farmaceutica que lo comprende
CA2860453C (en) * 2011-01-24 2020-04-28 Inceptum Research & Therapeutics, Inc. Compositions comprising a prostaglandin for treating neuropsychiatric conditions
CN107108556B (zh) * 2014-11-03 2020-09-29 艾欧米制药有限公司 药用化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993023035A2 (en) * 1992-05-18 1993-11-25 Smithkline Beecham Plc Use of indolone derivatives for the treatment of memory disorders, sexual dysfunction and parkinson's disease
AU6246198A (en) * 1997-02-18 1998-09-08 American Home Products Corporation 4-aminoethoxyindazole derivatives
GB0130219D0 (en) * 2001-12-18 2002-02-06 Pfizer Ltd Compounds for the treatment of sexual dysfunction
SI1572214T1 (sl) * 2002-12-10 2010-07-30 Pfizer Ltd Derivati morfolina za uporabo kot dopaminski agonisti pri zdravljenju med drugim spolne disfunkcije

Also Published As

Publication number Publication date
TW200607500A (en) 2006-03-01
WO2005116027A2 (en) 2005-12-08
IL179365A0 (en) 2007-03-08
BRPI0511533A (pt) 2008-01-02
UY28918A1 (es) 2005-12-30
MA28606B1 (fr) 2007-05-02
PE20060289A1 (es) 2006-04-22
ECSP067024A (es) 2006-12-29
EP1753763B1 (en) 2008-08-13
WO2005116027A3 (en) 2006-04-13
EA200601985A1 (ru) 2007-04-27
AR049191A1 (es) 2006-07-05
JP2008074874A (ja) 2008-04-03
PA8635001A1 (es) 2006-05-16
SV2005002128A (es) 2005-12-13
CA2568050A1 (en) 2005-12-08
ES2308492T3 (es) 2008-12-01
ATE404560T1 (de) 2008-08-15
NL1029128C2 (nl) 2006-06-14
JP2008500329A (ja) 2008-01-10
NO20065328L (no) 2006-12-18
JP4093588B2 (ja) 2008-06-04
NL1029128A1 (nl) 2005-11-30
EP1753763A2 (en) 2007-02-21
AP2006003823A0 (en) 2006-12-31
CR8772A (es) 2006-12-13
DE602005008954D1 (de) 2008-09-25
MXPA06013759A (es) 2007-02-08
AU2005247696A1 (en) 2005-12-08

Similar Documents

Publication Publication Date Title
GT200700024A (es) Derivados de amina
HN2011000193A (es) Derivados de piridazina como inhibidores de smo
GT200900027A (es) Compuestos organicos
GT200600024A (es) Derivados de triazol sustituidos como antagonistas de oxitocina
GT200500119A (es) Derivados de tetraazabenzo [e] azuleno y sus analogos
CY1112722T1 (el) Μυκητοκτονες συνθεσεις
CU20100238A7 (es) Derivados de isoxazol y su uso como potenciadores de los receptores metabotrópicos de glutamato
ECSP088688A (es) Piperidinoilpirrolidinas agonistas del receptor de melanocortina tipo 4
DOP2007000016A (es) Agentes citotoxicos que comprenden nuevos derivados de tomaimicina.
ECSP088989A (es) (aza)ciclohexanos carboxilados nuevos como ligandos de receptores de dopamina d3
CR10148A (es) Derivados de las benzamidas y heteroarenos
UY30709A1 (es) Nuevos derivados de 1,4-benzotiepina-1, 1-dioxido sustituidos con radicales bencilo, método para su preparacion, productos farmacéuticos que comprenden estos compuestos y su uso.
UY32147A (es) Derivados de indol y de indolina y métodos para usarlos
UY32296A (es) Nuevos compuestos
GT200800158A (es) Pirazolquinolonas como potentes inhibidores de parp
CR9786A (es) Compuestos de bencimidazol-tiofeno
UY29343A1 (es) Pirazolopiridinas y sales de las mismas, una composición farmacéutica que comprende dichos compuestos, un método para prepararlos y su uso.
UY29478A1 (es) Compuestos heteroaromaticos acilaminobiciclicos y sus usos
CO6260091A2 (es) Derivados de iminopiridina y su uso
ECSP11010816A (es) Nuevos Compuestos
HN2010000330A (es) DERIVADOS DE INDOL-2-ONA DISUSTITUIDOS EN 3 y SU PREPARACION
EA200801893A1 (ru) Производные тетрагидронафталина, способ их получения и их применение в качестве ингибиторов воспаления
UY30706A1 (es) Diaril, dipiridinil y arilpiridinil derivados y usos de los mismos
SV2005002015A (es) Procesos para la preparacion de haluros de aril- y heteroaril-alquilsulfonilo - ref. wyth0008-504 (am101302)
GT200500382A (es) Sulfonamido-macrociclos y sus sales como inhibidores de tie2, composicion farmaceutica que comprende estos compuestos, metodo de prepararlos y su uso