ECSP088473A - FORMAS DE CRISTAL F, G, H, I, y K DEL MESILATO DE IMATINIB - Google Patents
FORMAS DE CRISTAL F, G, H, I, y K DEL MESILATO DE IMATINIBInfo
- Publication number
- ECSP088473A ECSP088473A EC2008008473A ECSP088473A ECSP088473A EC SP088473 A ECSP088473 A EC SP088473A EC 2008008473 A EC2008008473 A EC 2008008473A EC SP088473 A ECSP088473 A EC SP088473A EC SP088473 A ECSP088473 A EC SP088473A
- Authority
- EC
- Ecuador
- Prior art keywords
- crystal form
- glass forms
- warm
- methyl
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Abstract
La invención se refiere a la forma de cristal-F, la forma de cristal-G, la forma de cristal-H, la forma de cristal-I, y la forma de cristal-K de la sal de adición de ácido metansulfónico de la 4-(4-metil-piperazin-1-ilmetil)-N-[4-metil-3-(4-(piridin-3-il)-pirimidin-2-ilamino)-fenil]-benzamida, a ciertos procesos para su preparación, a composiciones farmacéuticas que contienen estas formas de cristal, a su uso en métodos de diagnóstico o para el tratamiento terapéutico de animales de sangre caliente, y a su uso como un intermediario o para la preparación de preparaciones farmacéuticas para utilizarse en métodos de diagnóstico para el tratamiento terapéutico de animales de sangre caliente, en especial seres humanos.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0524062A GB0524062D0 (en) | 2005-11-25 | 2005-11-25 | Organic compounds |
GB0524061A GB0524061D0 (en) | 2005-11-25 | 2005-11-25 | Organic compounds |
US74001605P | 2005-11-28 | 2005-11-28 | |
US74001705P | 2005-11-28 | 2005-11-28 | |
US74001805P | 2005-11-28 | 2005-11-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP088473A true ECSP088473A (es) | 2008-06-30 |
Family
ID=37847165
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2008008473A ECSP088473A (es) | 2005-11-25 | 2008-05-20 | FORMAS DE CRISTAL F, G, H, I, y K DEL MESILATO DE IMATINIB |
Country Status (13)
Country | Link |
---|---|
US (6) | US7893076B2 (es) |
EP (3) | EP1960380A1 (es) |
JP (2) | JP5844508B2 (es) |
KR (4) | KR20130140909A (es) |
CN (1) | CN102351842B (es) |
AU (2) | AU2006316823A1 (es) |
BR (1) | BRPI0618993A2 (es) |
CA (3) | CA2824301C (es) |
EC (1) | ECSP088473A (es) |
MY (1) | MY146403A (es) |
NO (1) | NO20082684L (es) |
UY (1) | UY29964A1 (es) |
WO (1) | WO2007059963A1 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR047530A1 (es) * | 2004-02-04 | 2006-01-25 | Novartis Ag | Formas de sal de 4-(4-metilpiperazin-1-ilmetil)-n-(4-metil-3-(4-piridin-3-il)pirimidin-2-ilamino)fenil)-benzamida |
CA2824301C (en) * | 2005-11-25 | 2016-01-12 | Novartis Ag | F, g, h, i and k crystal forms of imatinib mesylate |
WO2009042809A1 (en) * | 2007-09-25 | 2009-04-02 | Teva Pharmaceutical Industries Ltd. | Stable imatinib compositions |
CZ2009570A3 (cs) | 2009-08-26 | 2011-03-09 | Zentiva, K. S. | Príprava, stabilizace a využití polymorfu imatinib mesylátu pro vývoj lékových forem |
PL389357A1 (pl) | 2009-10-22 | 2011-04-26 | Tomasz Koźluk | Sole imatinibu z pochodnymi kwasów winowych i sposób ich wytwarzania |
EP2536707A1 (en) | 2010-02-15 | 2012-12-26 | Reliance Life Sciences Pvt., Ltd. | Process for the preparation of alpha form of imatinib mesylate |
PL390611A1 (pl) | 2010-03-04 | 2011-09-12 | Tomasz Koźluk | Sposób otrzymywania polimorficznej formy alfa i nowa forma polimorficzna mesylanu imatinibu |
WO2012090221A1 (en) | 2010-12-29 | 2012-07-05 | Cadila Healthcare Limited | Novel salts of imatinib |
EP2604596A1 (en) * | 2011-12-16 | 2013-06-19 | Deva Holding Anonim Sirketi | Polymorphs of imatinib |
CA2877030A1 (en) | 2012-06-22 | 2013-12-27 | Basf Se | Multicomponent crystals comprising imatinib mesilate and selected co-crystal formers |
KR101242955B1 (ko) * | 2012-06-25 | 2013-03-12 | 제일약품주식회사 | 이마티닙 메실레이트 결정형 α의 제조 방법 |
EP2803353B1 (en) | 2013-05-14 | 2018-05-23 | Hetero Research Foundation | Compositions of Imatinib |
WO2015081175A1 (en) * | 2013-11-26 | 2015-06-04 | Children's Medical Center Corporation | Expandable stent valve |
WO2018089404A1 (en) | 2016-11-11 | 2018-05-17 | Mallinckrodt Nuclear Medicine Llc | Processes for generating germanium-68 with reduced volatiles |
JP7263784B2 (ja) | 2019-01-11 | 2023-04-25 | 日本精工株式会社 | 自在継手用ヨーク |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW225528B (es) | 1992-04-03 | 1994-06-21 | Ciba Geigy Ag | |
CO4940418A1 (es) * | 1997-07-18 | 2000-07-24 | Novartis Ag | Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso |
US20060073185A1 (en) | 2002-12-13 | 2006-04-06 | Bausch & Lomb Incorporated | Method and composition for contact lenses |
US7300938B2 (en) * | 2003-06-02 | 2007-11-27 | Hetero Drugs Limited | Polymorphs of imatinib mesylate |
AR047530A1 (es) | 2004-02-04 | 2006-01-25 | Novartis Ag | Formas de sal de 4-(4-metilpiperazin-1-ilmetil)-n-(4-metil-3-(4-piridin-3-il)pirimidin-2-ilamino)fenil)-benzamida |
CA2555804C (en) * | 2004-02-11 | 2012-06-26 | Natco Pharma Limited | Polymorphic form of imatinib mesylate and a process for its preparation |
UA84462C2 (ru) | 2004-04-02 | 2008-10-27 | Институт Фармацевтични | Полиморфные модификации кислотно-аддитивных солей иматиниба с метансульфоновой кислотой |
BRPI0511805A (pt) | 2004-06-04 | 2008-01-15 | Bioniche Life Sciences Inc | uso de imatinib para tratar distúrbios hepáticos e infecções virais |
WO2006024863A1 (en) * | 2004-09-02 | 2006-03-09 | Cipla Limited | Stable crystal form of imatinib mesylate and process for the preparation thereof |
WO2006048890A1 (en) * | 2004-11-04 | 2006-05-11 | Sun Pharmaceutical Industries Limited | Imatinib mesylate crystal form and process for preparation thereof |
WO2006054314A1 (en) | 2004-11-17 | 2006-05-26 | Natco Pharma Limited | Polymorphic forms of imatinib mesylate |
US9804295B2 (en) | 2005-05-05 | 2017-10-31 | Novartis Ag | Ophthalmic devices for sustained delivery of active compounds |
GB0511066D0 (en) | 2005-05-31 | 2005-07-06 | Novartis Ag | Organic compounds |
AR055613A1 (es) * | 2005-08-26 | 2007-08-29 | Novartis Ag | Formas cristalinas delta y epsilon de mesilato de imatinib |
CA2824301C (en) * | 2005-11-25 | 2016-01-12 | Novartis Ag | F, g, h, i and k crystal forms of imatinib mesylate |
-
2006
- 2006-11-23 CA CA2824301A patent/CA2824301C/en not_active Expired - Fee Related
- 2006-11-23 EP EP06818763A patent/EP1960380A1/en not_active Withdrawn
- 2006-11-23 EP EP12177131.5A patent/EP2578580A1/en not_active Withdrawn
- 2006-11-23 AU AU2006316823A patent/AU2006316823A1/en not_active Abandoned
- 2006-11-23 US US12/094,629 patent/US7893076B2/en not_active Expired - Fee Related
- 2006-11-23 UY UY29964A patent/UY29964A1/es not_active Application Discontinuation
- 2006-11-23 EP EP12177119A patent/EP2546248A1/en not_active Withdrawn
- 2006-11-23 BR BRPI0618993-8A patent/BRPI0618993A2/pt not_active IP Right Cessation
- 2006-11-23 CN CN201110232553.6A patent/CN102351842B/zh not_active Expired - Fee Related
- 2006-11-23 KR KR1020137031544A patent/KR20130140909A/ko not_active Application Discontinuation
- 2006-11-23 JP JP2008541641A patent/JP5844508B2/ja not_active Expired - Fee Related
- 2006-11-23 CA CA2824307A patent/CA2824307C/en not_active Expired - Fee Related
- 2006-11-23 MY MYPI20081624A patent/MY146403A/en unknown
- 2006-11-23 KR KR1020137031545A patent/KR20130137721A/ko not_active Application Discontinuation
- 2006-11-23 KR KR1020137031543A patent/KR20130141712A/ko not_active Application Discontinuation
- 2006-11-23 WO PCT/EP2006/011240 patent/WO2007059963A1/en active Application Filing
- 2006-11-23 KR KR1020087012363A patent/KR20080078804A/ko not_active Application Discontinuation
- 2006-11-23 CA CA2628330A patent/CA2628330C/en not_active Expired - Fee Related
-
2008
- 2008-05-20 EC EC2008008473A patent/ECSP088473A/es unknown
- 2008-06-16 NO NO20082684A patent/NO20082684L/no not_active Application Discontinuation
-
2011
- 2011-01-14 US US13/006,505 patent/US8198289B2/en not_active Expired - Fee Related
- 2011-03-22 AU AU2011201286A patent/AU2011201286A1/en not_active Ceased
- 2011-07-15 US US13/183,557 patent/US8507515B2/en not_active Expired - Fee Related
- 2011-07-15 US US13/183,572 patent/US8592440B2/en not_active Expired - Fee Related
- 2011-07-15 US US13/183,600 patent/US8846706B2/en not_active Expired - Fee Related
-
2012
- 2012-05-15 US US13/472,000 patent/US8633213B2/en not_active Expired - Fee Related
-
2014
- 2014-01-16 JP JP2014005741A patent/JP2014074067A/ja active Pending
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