ECSP066331A - Compuestos de sulfonamidas derivados de benzoxazinona, su preparación y uso comun como medicamentos - Google Patents
Compuestos de sulfonamidas derivados de benzoxazinona, su preparación y uso comun como medicamentosInfo
- Publication number
- ECSP066331A ECSP066331A EC2006006331A ECSP066331A ECSP066331A EC SP066331 A ECSP066331 A EC SP066331A EC 2006006331 A EC2006006331 A EC 2006006331A EC SP066331 A ECSP066331 A EC SP066331A EC SP066331 A ECSP066331 A EC SP066331A
- Authority
- EC
- Ecuador
- Prior art keywords
- preparation
- compounds derived
- benzoxazinona
- sulfonamid
- medications
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- HQQTZCPKNZVLFF-UHFFFAOYSA-N 4h-1,2-benzoxazin-3-one Chemical compound C1=CC=C2ONC(=O)CC2=C1 HQQTZCPKNZVLFF-UHFFFAOYSA-N 0.000 abstract 2
- 229940124530 sulfonamide Drugs 0.000 abstract 2
- -1 sulfonamide compounds Chemical class 0.000 abstract 2
- 108091005435 5-HT6 receptors Proteins 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La presente invención se refiere a compuestos de sulfonamidas derivados de benzoxazinona de fórmula general (l), a un procedimiento para su preparación, a un medicamento que comprende estos compuestos de sulfonamidas derivadas de benzoxazinona para la preparación de medicamentos para regulación del receptor 5- HT6 así como para el tratamiento de trastornos relacionados al mismo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200301812A ES2232292B1 (es) | 2003-07-30 | 2003-07-30 | Compuestos sulfonamidicos derivados de benzoxazinona, su preparacion y uso como medicamentos. |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP066331A true ECSP066331A (es) | 2006-08-30 |
Family
ID=34130545
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2006006331A ECSP066331A (es) | 2003-07-30 | 2006-01-30 | Compuestos de sulfonamidas derivados de benzoxazinona, su preparación y uso comun como medicamentos |
Country Status (23)
Country | Link |
---|---|
US (1) | US20070032482A1 (es) |
EP (1) | EP1648886B1 (es) |
JP (1) | JP2007500161A (es) |
KR (1) | KR20060056355A (es) |
CN (1) | CN1860114A (es) |
AR (1) | AR045153A1 (es) |
AT (1) | ATE451366T1 (es) |
AU (1) | AU2004263300A1 (es) |
BR (1) | BRPI0413101A (es) |
CA (1) | CA2534095A1 (es) |
CL (1) | CL2004001929A1 (es) |
DE (1) | DE602004024538D1 (es) |
EC (1) | ECSP066331A (es) |
ES (2) | ES2232292B1 (es) |
IL (1) | IL173004A0 (es) |
MX (1) | MXPA06001228A (es) |
NO (1) | NO20060969L (es) |
PE (1) | PE20050724A1 (es) |
PT (1) | PT1648886E (es) |
RU (1) | RU2006105714A (es) |
TW (1) | TW200510354A (es) |
WO (1) | WO2005014589A1 (es) |
ZA (1) | ZA200600426B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007533749A (ja) * | 2004-04-20 | 2007-11-22 | アムゲン インコーポレイティッド | アリールスルホンアミドおよびそれに関連する使用方法 |
AR058277A1 (es) | 2005-12-09 | 2008-01-30 | Solvay Pharm Gmbh | N- sulfamoil - piperidin - amidas, composiciones farmaceuticas que las comprenden y procedimiento para su preparacion |
GB2435825A (en) * | 2006-03-09 | 2007-09-12 | Esteve Labor Dr | Benzimidazole-2- & pyrido[d]imidazole-2- sulphonamide derivatives for treatment of disorders mediated via 5-HT6 receptors, eg those related to food intake |
EP2053052A1 (en) | 2007-10-23 | 2009-04-29 | Laboratorios del Dr. Esteve S.A. | Process for the preparation of 6-substituted imidazo[2,1-b]thiazole-5-sulfonyl halide |
JP7113810B2 (ja) | 2016-07-07 | 2022-08-05 | ブリストル-マイヤーズ スクイブ カンパニー | Rock阻害剤としてのスピロラクタム |
GB201713780D0 (en) * | 2017-08-29 | 2017-10-11 | E-Therapeutics Plc | Modulators of hedgehog (Hh) signalling pathway |
CN109232599B (zh) * | 2018-10-08 | 2021-04-20 | 广西中医药大学 | 具有抗肿瘤活性的o-对三氟甲基苯甲酰基土甘草a及其制备方法和用途 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4344945A (en) * | 1980-03-10 | 1982-08-17 | Kyowa Hakko Kogyo Co., Ltd. | Piperidine derivatives |
TW199153B (es) * | 1990-08-07 | 1993-02-01 | Dtsuka Seiyaku Kk | |
ATE216580T1 (de) * | 1993-07-16 | 2002-05-15 | Merck & Co Inc | Benzoxazinon- und benzopyrimidinon- piperidinyl- verbindungen als tokolytische oxytocin-rezeptor- antagonisten |
CZ294413B6 (cs) * | 1996-03-29 | 2004-12-15 | Duphar International Research B. V. | Piperazinová nebo piperidinová sloučenina, způsob její přípravy, farmaceutický prostředek tuto sloučeninu obsahující a použití této sloučeniny pro přípravu farmaceutického přípravku |
CN1074764C (zh) * | 1996-05-29 | 2001-11-14 | 沃尼尔·朗伯公司 | 苯并噁嗪酮多巴胺d4受体拮抗剂 |
SE9904652D0 (sv) * | 1999-12-17 | 1999-12-17 | Astra Pharma Prod | Novel Compounds |
DZ3370A1 (fr) * | 2000-05-12 | 2001-11-15 | Solvay Pharm Bv | Composes de piperazine et piperidine |
-
2003
- 2003-07-30 ES ES200301812A patent/ES2232292B1/es not_active Expired - Fee Related
-
2004
- 2004-07-29 JP JP2006521525A patent/JP2007500161A/ja active Pending
- 2004-07-29 RU RU2006105714/04A patent/RU2006105714A/ru unknown
- 2004-07-29 US US10/566,404 patent/US20070032482A1/en not_active Abandoned
- 2004-07-29 EP EP04741318A patent/EP1648886B1/en active Active
- 2004-07-29 BR BRPI0413101-0A patent/BRPI0413101A/pt not_active Application Discontinuation
- 2004-07-29 PT PT04741318T patent/PT1648886E/pt unknown
- 2004-07-29 AU AU2004263300A patent/AU2004263300A1/en not_active Abandoned
- 2004-07-29 DE DE602004024538T patent/DE602004024538D1/de active Active
- 2004-07-29 AR ARP040102695A patent/AR045153A1/es unknown
- 2004-07-29 ZA ZA200600426A patent/ZA200600426B/en unknown
- 2004-07-29 CN CNA2004800280755A patent/CN1860114A/zh active Pending
- 2004-07-29 ES ES04741318T patent/ES2338008T3/es active Active
- 2004-07-29 WO PCT/EP2004/008507 patent/WO2005014589A1/en active Application Filing
- 2004-07-29 CL CL200401929A patent/CL2004001929A1/es unknown
- 2004-07-29 AT AT04741318T patent/ATE451366T1/de not_active IP Right Cessation
- 2004-07-29 TW TW093122663A patent/TW200510354A/zh unknown
- 2004-07-29 CA CA002534095A patent/CA2534095A1/en not_active Abandoned
- 2004-07-29 MX MXPA06001228A patent/MXPA06001228A/es active IP Right Grant
- 2004-07-29 KR KR1020067002066A patent/KR20060056355A/ko not_active Application Discontinuation
- 2004-08-02 PE PE2004000733A patent/PE20050724A1/es not_active Application Discontinuation
-
2006
- 2006-01-05 IL IL173004A patent/IL173004A0/en unknown
- 2006-01-30 EC EC2006006331A patent/ECSP066331A/es unknown
- 2006-02-28 NO NO20060969A patent/NO20060969L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ES2232292A1 (es) | 2005-05-16 |
ES2338008T3 (es) | 2010-05-03 |
PT1648886E (pt) | 2010-03-10 |
EP1648886A1 (en) | 2006-04-26 |
KR20060056355A (ko) | 2006-05-24 |
ZA200600426B (en) | 2007-03-28 |
BRPI0413101A (pt) | 2006-10-03 |
NO20060969L (no) | 2006-04-11 |
RU2006105714A (ru) | 2007-09-20 |
EP1648886B1 (en) | 2009-12-09 |
AU2004263300A1 (en) | 2005-02-17 |
ES2232292B1 (es) | 2006-11-01 |
IL173004A0 (en) | 2006-06-11 |
AR045153A1 (es) | 2005-10-19 |
ATE451366T1 (de) | 2009-12-15 |
PE20050724A1 (es) | 2005-11-16 |
US20070032482A1 (en) | 2007-02-08 |
JP2007500161A (ja) | 2007-01-11 |
TW200510354A (en) | 2005-03-16 |
CA2534095A1 (en) | 2005-01-27 |
MXPA06001228A (es) | 2006-05-15 |
DE602004024538D1 (de) | 2010-01-21 |
CL2004001929A1 (es) | 2005-06-03 |
WO2005014589A1 (en) | 2005-02-17 |
CN1860114A (zh) | 2006-11-08 |
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