ECSP045518A - Secuencias de control del gen de corina humano - Google Patents
Secuencias de control del gen de corina humanoInfo
- Publication number
- ECSP045518A ECSP045518A EC2004005518A ECSP045518A ECSP045518A EC SP045518 A ECSP045518 A EC SP045518A EC 2004005518 A EC2004005518 A EC 2004005518A EC SP045518 A ECSP045518 A EC SP045518A EC SP045518 A ECSP045518 A EC SP045518A
- Authority
- EC
- Ecuador
- Prior art keywords
- corina
- human
- control sequences
- control region
- gen control
- Prior art date
Links
- 210000002064 heart cell Anatomy 0.000 abstract 1
- 208000019622 heart disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pathology (AREA)
- Plant Pathology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Nueva región de control de la expresión aislada de genes de corina de mamífero. Esta región de control activa preferencialmente la transcripción en células cardíacas. Se proveen métodos y composiciones para emplear esta región de control en la identificación de agentes capaces de modular la expresión de corina y en el tratamiento de enfermedades cardíacas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38410802P | 2002-05-31 | 2002-05-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP045518A true ECSP045518A (es) | 2005-03-10 |
Family
ID=29711979
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2004005518A ECSP045518A (es) | 2002-05-31 | 2004-12-28 | Secuencias de control del gen de corina humano |
Country Status (18)
Country | Link |
---|---|
US (1) | US20030223976A1 (es) |
EP (1) | EP1546172A4 (es) |
JP (1) | JP2005531302A (es) |
KR (1) | KR20050009724A (es) |
CN (1) | CN1671729A (es) |
AU (1) | AU2003245342A1 (es) |
BR (1) | BR0311603A (es) |
CA (1) | CA2487024A1 (es) |
CR (1) | CR7622A (es) |
EC (1) | ECSP045518A (es) |
IL (1) | IL165244A0 (es) |
MX (1) | MXPA04011944A (es) |
NO (1) | NO20045722L (es) |
PL (1) | PL374125A1 (es) |
RS (1) | RS104404A (es) |
RU (1) | RU2004139055A (es) |
WO (1) | WO2003102135A2 (es) |
ZA (1) | ZA200410400B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050026255A1 (en) * | 2002-06-25 | 2005-02-03 | Morser John Michael | Corin, a serine protease |
WO2005084223A2 (en) * | 2004-02-27 | 2005-09-15 | The General Hospital Corporation | Methods and compositions for hair growth |
EP2172455B1 (en) | 2005-12-01 | 2011-01-19 | Basf Se | Oxime ester photoinitiators |
US20110306069A1 (en) | 2009-02-19 | 2011-12-15 | Qingyu Wu | Corin As A Marker For Heart Failure |
CN105734070A (zh) * | 2016-04-11 | 2016-07-06 | 苏州大学 | Corin基因变异体及其用途 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5917123A (en) * | 1997-03-14 | 1999-06-29 | University Of Pittsburgh | Transgenic mice containing a nucleic acid encoding tumor necrosis factor-α under the control of a cardiac specific regulatory region |
HUP0102811A3 (en) * | 1998-06-05 | 2005-11-28 | Schering Ag | Corin, a serine protease |
WO2001057188A2 (en) * | 2000-02-03 | 2001-08-09 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
CA2296792A1 (en) * | 1999-02-26 | 2000-08-26 | Genset S.A. | Expressed sequence tags and encoded human proteins |
ATE496123T1 (de) * | 2000-02-03 | 2011-02-15 | Dendreon Corp | Nukleinsäuren, welche für tramsmembran serin proteasen kodieren, die kodierten proteine und darauf basierende methoden |
JP2001245671A (ja) * | 2000-03-07 | 2001-09-11 | Chiba Prefecture | ヒト神経芽細胞腫においてクローニングされた新規遺伝子及び新規遺伝子の断片 |
-
2003
- 2003-05-28 PL PL03374125A patent/PL374125A1/xx not_active Application Discontinuation
- 2003-05-28 RU RU2004139055/13A patent/RU2004139055A/ru not_active Application Discontinuation
- 2003-05-28 MX MXPA04011944A patent/MXPA04011944A/es not_active Application Discontinuation
- 2003-05-28 US US10/447,476 patent/US20030223976A1/en not_active Abandoned
- 2003-05-28 EP EP03738981A patent/EP1546172A4/en not_active Withdrawn
- 2003-05-28 KR KR10-2004-7019340A patent/KR20050009724A/ko not_active Application Discontinuation
- 2003-05-28 AU AU2003245342A patent/AU2003245342A1/en not_active Abandoned
- 2003-05-28 BR BR0311603-4A patent/BR0311603A/pt not_active IP Right Cessation
- 2003-05-28 CA CA002487024A patent/CA2487024A1/en not_active Abandoned
- 2003-05-28 JP JP2004510377A patent/JP2005531302A/ja active Pending
- 2003-05-28 CN CNA03818169XA patent/CN1671729A/zh active Pending
- 2003-05-28 RS YU104404A patent/RS104404A/sr unknown
- 2003-05-28 IL IL16524403A patent/IL165244A0/xx unknown
- 2003-05-28 WO PCT/US2003/016741 patent/WO2003102135A2/en active Application Filing
-
2004
- 2004-12-15 CR CR7622A patent/CR7622A/es not_active Application Discontinuation
- 2004-12-23 ZA ZA200410400A patent/ZA200410400B/en unknown
- 2004-12-28 EC EC2004005518A patent/ECSP045518A/es unknown
- 2004-12-30 NO NO20045722A patent/NO20045722L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR20050009724A (ko) | 2005-01-25 |
PL374125A1 (en) | 2005-10-03 |
WO2003102135A3 (en) | 2004-11-04 |
BR0311603A (pt) | 2005-06-07 |
EP1546172A2 (en) | 2005-06-29 |
CR7622A (es) | 2006-05-29 |
US20030223976A1 (en) | 2003-12-04 |
MXPA04011944A (es) | 2005-03-31 |
CA2487024A1 (en) | 2003-12-11 |
AU2003245342A1 (en) | 2003-12-19 |
EP1546172A4 (en) | 2005-11-30 |
RS104404A (en) | 2006-12-15 |
WO2003102135A2 (en) | 2003-12-11 |
JP2005531302A (ja) | 2005-10-20 |
IL165244A0 (en) | 2005-12-18 |
ZA200410400B (en) | 2006-06-28 |
NO20045722L (no) | 2004-12-30 |
CN1671729A (zh) | 2005-09-21 |
RU2004139055A (ru) | 2005-08-20 |
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