EA202190531A1 - Коллекции пептидов, пептидные агенты и способы их применения - Google Patents
Коллекции пептидов, пептидные агенты и способы их примененияInfo
- Publication number
- EA202190531A1 EA202190531A1 EA202190531A EA202190531A EA202190531A1 EA 202190531 A1 EA202190531 A1 EA 202190531A1 EA 202190531 A EA202190531 A EA 202190531A EA 202190531 A EA202190531 A EA 202190531A EA 202190531 A1 EA202190531 A1 EA 202190531A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- peptides
- collections
- methods
- application
- peptide agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Virology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862719996P | 2018-08-20 | 2018-08-20 | |
| PCT/US2019/047206 WO2020041270A1 (en) | 2018-08-20 | 2019-08-20 | Collections of peptides, peptide agents, and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA202190531A1 true EA202190531A1 (ru) | 2021-08-09 |
Family
ID=69591277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA202190531A EA202190531A1 (ru) | 2018-08-20 | 2019-08-20 | Коллекции пептидов, пептидные агенты и способы их применения |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US12398178B2 (enExample) |
| EP (1) | EP3840766A4 (enExample) |
| JP (1) | JP2021535108A (enExample) |
| KR (1) | KR20210060482A (enExample) |
| CN (1) | CN113039195A (enExample) |
| AU (1) | AU2019326423A1 (enExample) |
| BR (1) | BR112021003113A2 (enExample) |
| CA (1) | CA3110082A1 (enExample) |
| EA (1) | EA202190531A1 (enExample) |
| IL (1) | IL280931A (enExample) |
| MA (1) | MA53446A (enExample) |
| MX (1) | MX2021001943A (enExample) |
| SG (1) | SG11202101672YA (enExample) |
| WO (1) | WO2020041270A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112020004555A2 (pt) * | 2017-09-07 | 2020-09-24 | Fog Pharmaceuticals, Inc. | agentes que modulam funções de beta-catenina e métodos dos mesmos |
| AU2019326423A1 (en) | 2018-08-20 | 2021-04-08 | Fog Pharmaceuticals, Inc. | Collections of peptides, peptide agents, and methods of use thereof |
| GB201909103D0 (en) * | 2019-06-25 | 2019-08-07 | Univ Bath | Compounds |
| BR112023025528A2 (pt) * | 2021-06-08 | 2024-02-27 | Fog Pharmaceuticals Inc | Peptídeos grampeados e métodos destes |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1680443B9 (en) | 2003-11-05 | 2014-09-03 | Dana-Farber Cancer Institute, Inc. | Stabilized alpha helical peptides and uses thereof |
| JP2010510236A (ja) | 2006-11-15 | 2010-04-02 | ダナ−ファーバー キャンサー インスティテュート インク． | 安定化させたｍａｍｌペプチドおよびその使用法 |
| CA2686827C (en) | 2006-12-14 | 2014-09-16 | Aileron Therapeutics, Inc. | Bis-sulfhydryl macrocyclization systems |
| US8889632B2 (en) | 2007-01-31 | 2014-11-18 | Dana-Farber Cancer Institute, Inc. | Stabilized p53 peptides and uses thereof |
| EP2508531B1 (en) | 2007-03-28 | 2016-10-19 | President and Fellows of Harvard College | Stitched polypeptides |
| US10716828B2 (en) | 2007-05-02 | 2020-07-21 | Dana-Farber Cancer Institute, Inc. | Methods of modulating cellular homeostatic pathways and cellular survival |
| EP2208061B1 (en) | 2007-09-26 | 2017-11-08 | Dana Farber Cancer Institute | Methods and compositions for modulating bcl-2 family polypeptides |
| JP5788178B2 (ja) | 2008-01-23 | 2015-09-30 | ダナ ファーバー キャンサー インスティテュート インコーポレイテッド | ウィルス感染症の治療のための組成物及び方法 |
| EP2356139A4 (en) | 2008-07-23 | 2013-01-09 | Harvard College | LIGURE COMBINED POLYPEPTIDES |
| EP3401684B1 (en) | 2008-10-10 | 2022-03-16 | Dana Farber Cancer Institute, Inc. | Chemical modulators of pro-apoptotic bax and bcl-2 polypeptides |
| EP3549951A3 (en) | 2008-12-09 | 2019-11-20 | Dana Farber Cancer Institute, Inc. | Methods and compositions for specific modulation of mcl-1 |
| EP3698811A1 (en) | 2009-06-18 | 2020-08-26 | Dana Farber Cancer Institute, Inc. | Structured viral peptide compositions and methods of use |
| WO2011008260A2 (en) | 2009-07-13 | 2011-01-20 | President And Fellows Of Harvard College | Bifunctional stapled polypeptides and uses thereof |
| US20130035304A1 (en) | 2010-01-29 | 2013-02-07 | Walensky Loren D | Small molecules for the modulation of mcl-1 and methods of modulating cell death, cell division, cell differentiation and methods of treating disorders |
| AU2011274474B2 (en) | 2010-07-09 | 2015-06-18 | Dana-Farber Cancer Institute, Inc. | Stabilized insulinotropic peptides and methods of use |
| WO2012040459A2 (en) * | 2010-09-22 | 2012-03-29 | President And Fellows Of Harvard College | Beta-catenin targeting peptides and uses thereof |
| EP2637680B1 (en) | 2010-11-12 | 2017-03-01 | Dana-Farber Cancer Institute, Inc. | Cancer therapies |
| CA2833171C (en) | 2011-04-15 | 2021-08-31 | Loren D. Walensky | Targeting deregulated wnt signaling in cancer using stabilized alpha-helices of bcl-9 |
| WO2012174423A1 (en) | 2011-06-17 | 2012-12-20 | President And Fellows Of Harvard College | Stabilized polypeptides as regulators of rab gtpase function |
| WO2012174409A1 (en) | 2011-06-17 | 2012-12-20 | President And Fellows Of Harvard College | Stabilized variant maml peptides and uses thereof |
| CA3173988A1 (en) | 2011-10-11 | 2013-04-18 | Dana-Farber Cancer Institute, Inc. | Pyrazol-3-ones that activate pro-apoptotic bax |
| WO2013102211A2 (en) | 2011-12-29 | 2013-07-04 | Walensky Loren D | Stabilized antiviral fusion helices |
| AU2013235425B2 (en) | 2012-03-20 | 2017-09-21 | Dana Farber Cancer Institute, Inc. | Inhibition of MCL-1 and/or BFL-1/A1 |
| CA3113959A1 (en) | 2012-09-26 | 2014-04-03 | President And Fellows Of Harvard College | Proline-locked stapled peptides and uses thereof |
| WO2014055564A1 (en) | 2012-10-01 | 2014-04-10 | President And Fellows Of Harvard College | Stabilized polypeptide insulin receptor modulators |
| EP3782638A1 (en) | 2013-03-13 | 2021-02-24 | President and Fellows of Harvard College | Stapled and stitched polypeptides and uses thereof |
| CA2906775A1 (en) | 2013-03-15 | 2014-09-18 | Dana-Farber Cancer Institute, Inc. | Bh4 stabilized peptides and uses thereof |
| WO2014151369A2 (en) | 2013-03-15 | 2014-09-25 | Dana-Farber Cancer Institute, Inc. | Stabilized ezh2 peptides |
| WO2014144148A1 (en) | 2013-03-15 | 2014-09-18 | Dana-Farber Cancer Institute, Inc. | Stabilized sos1 peptides |
| WO2014197821A1 (en) | 2013-06-06 | 2014-12-11 | President And Fellows Of Harvard College | Homeodomain fusion proteins and uses thereof |
| WO2014201370A1 (en) | 2013-06-14 | 2014-12-18 | President And Fellows Of Harvard College | Stabilized polypeptide insulin receptor modulators |
| US20160244494A1 (en) | 2013-10-01 | 2016-08-25 | President And Fellows Of Harvard College | Stabilized polypeptides and uses thereof |
| US10039809B2 (en) | 2013-12-18 | 2018-08-07 | The California Institute For Biomedical Research | Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof |
| CN114805527A (zh) | 2014-05-21 | 2022-07-29 | 哈佛大学的校长及成员们 | Ras抑制肽和其用途 |
| EP3270945A4 (en) | 2015-03-18 | 2018-09-05 | Massachusetts Institute of Technology | Selective mcl-1 binding peptides |
| EP3310373A4 (en) | 2015-06-22 | 2019-02-13 | University of Utah Research Foundation | Thiol-ene based peptide stapling and uses thereof |
| US10464975B2 (en) | 2015-07-02 | 2019-11-05 | Dana-Farber Cancer Institute, Inc. | Stabilized anti-microbial peptides |
| JP7049989B2 (ja) | 2015-08-28 | 2022-04-07 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | Ｂｆｌ－１と結合するペプチド |
| US20190002506A1 (en) | 2015-08-28 | 2019-01-03 | Dana-Farber Cancer Institute, Inc. | Stabilized peptides for covalent binding to target protein |
| US10280317B2 (en) | 2016-07-07 | 2019-05-07 | Northwestern University | Enhanced conductivity, adhesion and environmental stability of printed graphene inks with nitrocellulose |
| US11034720B2 (en) * | 2016-07-17 | 2021-06-15 | University Of Utah Research Foundation | Thiol-yne based peptide stapling and uses thereof |
| BR112020004555A2 (pt) | 2017-09-07 | 2020-09-24 | Fog Pharmaceuticals, Inc. | agentes que modulam funções de beta-catenina e métodos dos mesmos |
| AU2019326423A1 (en) | 2018-08-20 | 2021-04-08 | Fog Pharmaceuticals, Inc. | Collections of peptides, peptide agents, and methods of use thereof |
| CA3159729A1 (en) | 2019-12-11 | 2021-06-17 | Amrita Singh CHANDHOKE | Technologies useful for assessing permeability |
| EP4121082A4 (en) | 2020-03-17 | 2024-05-01 | Fog Pharmaceuticals, Inc. | HELICALLY STAPLED PEPTIDES AND USES THEREOF |
| CA3186681A1 (en) | 2020-07-22 | 2022-01-27 | Brian Halbert WHITE | Stapled peptides and methods thereof |
| CN116113621A (zh) | 2020-07-22 | 2023-05-12 | 弗格制药有限公司 | 氨基酸 |
| BR112023025528A2 (pt) | 2021-06-08 | 2024-02-27 | Fog Pharmaceuticals Inc | Peptídeos grampeados e métodos destes |
| US20240376151A1 (en) | 2022-10-31 | 2024-11-14 | Fog Pharmaceuticals, Inc. | Stapled peptides and methods thereof |
| US20260207704A1 (en) | 2022-12-15 | 2026-07-23 | Parabilis Medicines, Inc. | Stapled peptides and methods thereof |
| WO2024130217A1 (en) | 2022-12-15 | 2024-06-20 | Fog Pharmaceuticals, Inc. | Stapled peptides and methods thereof |
-
2019
- 2019-08-20 AU AU2019326423A patent/AU2019326423A1/en not_active Abandoned
- 2019-08-20 CA CA3110082A patent/CA3110082A1/en active Pending
- 2019-08-20 EP EP19851876.3A patent/EP3840766A4/en not_active Withdrawn
- 2019-08-20 JP JP2021509747A patent/JP2021535108A/ja active Pending
- 2019-08-20 US US17/269,939 patent/US12398178B2/en active Active
- 2019-08-20 KR KR1020217008310A patent/KR20210060482A/ko not_active Withdrawn
- 2019-08-20 CN CN201980068943.9A patent/CN113039195A/zh active Pending
- 2019-08-20 EA EA202190531A patent/EA202190531A1/ru unknown
- 2019-08-20 MX MX2021001943A patent/MX2021001943A/es unknown
- 2019-08-20 MA MA053446A patent/MA53446A/fr unknown
- 2019-08-20 SG SG11202101672YA patent/SG11202101672YA/en unknown
- 2019-08-20 BR BR112021003113-8A patent/BR112021003113A2/pt not_active IP Right Cessation
- 2019-08-20 WO PCT/US2019/047206 patent/WO2020041270A1/en not_active Ceased
-
2021
- 2021-02-17 IL IL280931A patent/IL280931A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20210060482A (ko) | 2021-05-26 |
| SG11202101672YA (en) | 2021-03-30 |
| US12398178B2 (en) | 2025-08-26 |
| BR112021003113A2 (pt) | 2021-05-11 |
| US20210179665A1 (en) | 2021-06-17 |
| WO2020041270A1 (en) | 2020-02-27 |
| EP3840766A1 (en) | 2021-06-30 |
| EP3840766A4 (en) | 2022-06-22 |
| WO2020041270A9 (en) | 2020-05-07 |
| IL280931A (en) | 2021-04-29 |
| JP2021535108A (ja) | 2021-12-16 |
| CA3110082A1 (en) | 2020-02-27 |
| MX2021001943A (es) | 2021-07-15 |
| CN113039195A (zh) | 2021-06-25 |
| AU2019326423A1 (en) | 2021-04-08 |
| MA53446A (fr) | 2021-06-30 |
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