BR112023025528A2 - Peptídeos grampeados e métodos destes - Google Patents
Peptídeos grampeados e métodos destesInfo
- Publication number
- BR112023025528A2 BR112023025528A2 BR112023025528A BR112023025528A BR112023025528A2 BR 112023025528 A2 BR112023025528 A2 BR 112023025528A2 BR 112023025528 A BR112023025528 A BR 112023025528A BR 112023025528 A BR112023025528 A BR 112023025528A BR 112023025528 A2 BR112023025528 A2 BR 112023025528A2
- Authority
- BR
- Brazil
- Prior art keywords
- present disclosure
- disclosure provides
- catenin
- beta
- methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 102000015735 Beta-catenin Human genes 0.000 abstract 3
- 108060000903 Beta-catenin Proteins 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000005516 engineering process Methods 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
peptídeos grampeados e métodos destes. entre outras coisas, a presente divulgação fornece vários agentes úteis. em algumas modalidades, os agentes fornecidos podem se ligar a beta-catenina. em algumas modalidades, a presente divulgação fornece tecnologias para modular funções de beta-catenina. em algumas modalidades, a presente divulgação fornece tecnologias para prevenir e/ou tratar condições, distúrbios ou doenças associadas a beta-catenina. em algumas modalidades, a presente divulgação fornece agentes e aminoácidos projetados que podem fornecer propriedades e/ou atividades aprimoradas.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163208487P | 2021-06-08 | 2021-06-08 | |
| US202163224834P | 2021-07-22 | 2021-07-22 | |
| US202263303952P | 2022-01-27 | 2022-01-27 | |
| PCT/US2022/032738 WO2022261257A1 (en) | 2021-06-08 | 2022-06-08 | Stapled peptides and methods thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112023025528A2 true BR112023025528A2 (pt) | 2024-02-27 |
Family
ID=84425507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112023025528A BR112023025528A2 (pt) | 2021-06-08 | 2022-06-08 | Peptídeos grampeados e métodos destes |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP4355350A1 (pt) |
| KR (1) | KR20240031957A (pt) |
| BR (1) | BR112023025528A2 (pt) |
| CA (1) | CA3218824A1 (pt) |
| IL (1) | IL308790A (pt) |
| WO (1) | WO2022261257A1 (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11202001162TA (en) | 2017-09-07 | 2020-03-30 | Fog Pharmaceuticals Inc | Agents modulating beta-catenin functions and methods thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5731986B2 (ja) * | 2008-12-09 | 2015-06-10 | ダナ ファーバー キャンサー インスティテュート インコーポレイテッド | Ｍｃｌ−１の特異的調節の方法及び組成物 |
| WO2016085280A1 (ko) * | 2014-11-28 | 2016-06-02 | 서울대학교산학협력단 | 세포 투과성 스테이플 펩타이드, 이의 제조방법 및 그 용도 |
| US10011631B2 (en) * | 2015-12-01 | 2018-07-03 | The University Of Hong Kong | Stapled helical peptides and methods of synthesis |
| SG11202001162TA (en) * | 2017-09-07 | 2020-03-30 | Fog Pharmaceuticals Inc | Agents modulating beta-catenin functions and methods thereof |
| US11510991B2 (en) * | 2017-10-27 | 2022-11-29 | Ohio State Innovation Foundation | Polypeptide conjugates for intracellular delivery of stapled peptides |
-
2022
- 2022-06-08 BR BR112023025528A patent/BR112023025528A2/pt unknown
- 2022-06-08 CA CA3218824A patent/CA3218824A1/en active Pending
- 2022-06-08 IL IL308790A patent/IL308790A/en unknown
- 2022-06-08 WO PCT/US2022/032738 patent/WO2022261257A1/en active Application Filing
- 2022-06-08 EP EP22820994.6A patent/EP4355350A1/en active Pending
- 2022-06-08 KR KR1020237042998A patent/KR20240031957A/ko unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022261257A1 (en) | 2022-12-15 |
| IL308790A (en) | 2024-01-01 |
| EP4355350A1 (en) | 2024-04-24 |
| KR20240031957A (ko) | 2024-03-08 |
| CA3218824A1 (en) | 2022-12-15 |
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