EA202190368A1 - Модифицированные пакеты-мессенджеры растений и варианты их применения - Google Patents
Модифицированные пакеты-мессенджеры растений и варианты их примененияInfo
- Publication number
- EA202190368A1 EA202190368A1 EA202190368A EA202190368A EA202190368A1 EA 202190368 A1 EA202190368 A1 EA 202190368A1 EA 202190368 A EA202190368 A EA 202190368A EA 202190368 A EA202190368 A EA 202190368A EA 202190368 A1 EA202190368 A1 EA 202190368A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- cells
- uptake
- options
- application
- modified plant
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/34—Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Dispersion Chemistry (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Plant Pathology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Toxicology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pest Control & Pesticides (AREA)
- General Chemical & Material Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Botany (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862722576P | 2018-08-24 | 2018-08-24 | |
PCT/US2019/048046 WO2020041783A1 (fr) | 2018-08-24 | 2019-08-24 | Paquets de messagers végétaux modifiés et utilisations associées |
Publications (1)
Publication Number | Publication Date |
---|---|
EA202190368A1 true EA202190368A1 (ru) | 2021-06-10 |
Family
ID=69591371
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA202190368A EA202190368A1 (ru) | 2018-08-24 | 2019-08-24 | Модифицированные пакеты-мессенджеры растений и варианты их применения |
Country Status (17)
Country | Link |
---|---|
US (2) | US20210196632A1 (fr) |
EP (1) | EP3840728A4 (fr) |
JP (1) | JP2021533794A (fr) |
KR (1) | KR20210049138A (fr) |
CN (1) | CN112739327A (fr) |
AU (1) | AU2019325698A1 (fr) |
BR (1) | BR112021003311A2 (fr) |
CA (1) | CA3109958A1 (fr) |
CL (2) | CL2021000456A1 (fr) |
CO (1) | CO2021003128A2 (fr) |
EA (1) | EA202190368A1 (fr) |
IL (1) | IL280935A (fr) |
MA (1) | MA53443A (fr) |
MX (1) | MX2021001980A (fr) |
PH (1) | PH12021550354A1 (fr) |
SG (1) | SG11202101778TA (fr) |
WO (1) | WO2020041783A1 (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3099817A1 (fr) * | 2018-05-15 | 2019-11-21 | Flagship Pioneering Innovations Vi, Llc | Compositions de lutte contre les agents pathogenes et leurs utilisations |
CN116849231A (zh) * | 2018-05-15 | 2023-10-10 | 旗舰创业创新六公司 | 有害生物防治组合物及其用途 |
JP2022526678A (ja) * | 2019-04-13 | 2022-05-25 | フラッグシップ パイオニアリング イノベーションズ シックス,エルエルシー | ポリペプチドを封入する植物メッセンジャーパック及びその使用 |
MX2021012886A (es) * | 2019-04-25 | 2022-01-04 | Flagship Pioneering Innovations Vi Llc | Composiciones y metodos relacionados con paquetes mensajeros de plantas. |
CA3151814A1 (fr) * | 2019-08-24 | 2021-03-04 | Flagship Pioneering Innovations Vi, Llc | Modification de paquets de messagerie vegetale avec des lipides charges |
WO2021237215A1 (fr) * | 2020-05-22 | 2021-11-25 | University Of Louisville Research Foundation, Inc. | Compositions et méthodes de prévention et/ou de traitement d'infections microbiennes |
CN111748562B (zh) * | 2020-06-15 | 2022-04-29 | 华南农业大学 | 一种水稻纹枯病菌Atg 22蛋白编码基因及其靶标片段Rsatg22和应用 |
CN112646734B (zh) * | 2020-12-31 | 2022-11-29 | 广西壮族自治区林业科学研究院 | 一株兰花菌根真菌pf06及其应用 |
KR20240044415A (ko) * | 2021-06-14 | 2024-04-04 | 플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 | 식물 메신저 팩의 변형 |
CN114544800B (zh) * | 2022-01-14 | 2023-07-11 | 南通市疾病预防控制中心 | 分子筛串联固相萃取检测甲氧基丙烯酸酯类杀菌剂的方法 |
CN115161215A (zh) * | 2022-03-11 | 2022-10-11 | 中国农业大学 | 一种双歧杆菌的发酵方法及其应用 |
CN114958657B (zh) * | 2022-05-10 | 2023-09-05 | 广东省科学院生物与医学工程研究所 | Chitinophaga eiseniae降解羽毛粉产生生物表面活性剂的应用 |
CN117363664A (zh) * | 2023-08-03 | 2024-01-09 | 长春师范大学 | 一种从牛筋草内生菌Bipolaris sp.提取邻苯二甲酸二丁酯的方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4920016A (en) * | 1986-12-24 | 1990-04-24 | Linear Technology, Inc. | Liposomes with enhanced circulation time |
FR2836043B1 (fr) * | 2002-02-15 | 2004-06-04 | Inst Nat Sante Rech Med | Vesicules lipidiques, preparation et utilisations |
US7404969B2 (en) * | 2005-02-14 | 2008-07-29 | Sirna Therapeutics, Inc. | Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules |
JP6184945B2 (ja) * | 2011-06-08 | 2017-08-23 | シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド | mRNA送達のための脂質ナノ粒子組成物および方法 |
US20140308212A1 (en) * | 2011-11-07 | 2014-10-16 | University Of Louisville Research Foundation, Inc. | Edible plant-derived microvesicle compositions for diagnosis and treatment of disease |
EA201492055A1 (ru) * | 2012-06-08 | 2015-11-30 | Шир Хьюман Дженетик Терапис, Инк. | ИНГАЛЯЦИОННАЯ ДОСТАВКА мРНК В НЕЛЕГОЧНЫЕ КЛЕТКИ-МИШЕНИ |
JP6137894B2 (ja) * | 2013-03-22 | 2017-05-31 | 国立大学法人京都大学 | リポソーム−エキソソームハイブリッドベシクル及びその調製法 |
AU2016288643A1 (en) * | 2015-07-02 | 2018-02-22 | University Of Louisville Research Foundation, Inc. | Edible plant-derived microvesicle compositions for delivery of miRNA and methods for treatment of cancer |
MA46762A (fr) * | 2016-11-10 | 2019-09-18 | Translate Bio Inc | Procédé amélioré de préparation de nanoparticules lipidiques chargées d'arnm |
WO2018107061A1 (fr) * | 2016-12-09 | 2018-06-14 | Board Of Regents, The University Of Texas System | Nano-plateforme hybride exosomale-polymère (hexpo) pour l'administration d'agents thérapeutiques à base d'arni |
-
2019
- 2019-08-24 CN CN201980055476.6A patent/CN112739327A/zh active Pending
- 2019-08-24 US US17/270,110 patent/US20210196632A1/en not_active Abandoned
- 2019-08-24 AU AU2019325698A patent/AU2019325698A1/en active Pending
- 2019-08-24 EP EP19851037.2A patent/EP3840728A4/fr active Pending
- 2019-08-24 WO PCT/US2019/048046 patent/WO2020041783A1/fr unknown
- 2019-08-24 MA MA053443A patent/MA53443A/fr unknown
- 2019-08-24 CA CA3109958A patent/CA3109958A1/fr active Pending
- 2019-08-24 SG SG11202101778TA patent/SG11202101778TA/en unknown
- 2019-08-24 EA EA202190368A patent/EA202190368A1/ru unknown
- 2019-08-24 JP JP2021509222A patent/JP2021533794A/ja active Pending
- 2019-08-24 BR BR112021003311-4A patent/BR112021003311A2/pt unknown
- 2019-08-24 KR KR1020217008558A patent/KR20210049138A/ko unknown
- 2019-08-24 MX MX2021001980A patent/MX2021001980A/es unknown
-
2021
- 2021-02-17 IL IL280935A patent/IL280935A/en unknown
- 2021-02-19 PH PH12021550354A patent/PH12021550354A1/en unknown
- 2021-02-23 CL CL2021000456A patent/CL2021000456A1/es unknown
- 2021-03-10 CO CONC2021/0003128A patent/CO2021003128A2/es unknown
- 2021-07-23 US US17/383,821 patent/US20220273565A1/en active Pending
-
2023
- 2023-05-16 CL CL2023001410A patent/CL2023001410A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
JP2021533794A (ja) | 2021-12-09 |
PH12021550354A1 (en) | 2021-10-04 |
US20220273565A1 (en) | 2022-09-01 |
WO2020041783A1 (fr) | 2020-02-27 |
CA3109958A1 (fr) | 2020-02-27 |
IL280935A (en) | 2021-04-29 |
BR112021003311A2 (pt) | 2021-05-25 |
CL2023001410A1 (es) | 2023-10-30 |
MX2021001980A (es) | 2021-05-27 |
US20210196632A1 (en) | 2021-07-01 |
AU2019325698A1 (en) | 2021-04-08 |
CO2021003128A2 (es) | 2021-07-30 |
CL2021000456A1 (es) | 2021-07-23 |
EP3840728A4 (fr) | 2022-06-08 |
MA53443A (fr) | 2021-12-01 |
CN112739327A (zh) | 2021-04-30 |
SG11202101778TA (en) | 2021-03-30 |
KR20210049138A (ko) | 2021-05-04 |
EP3840728A1 (fr) | 2021-06-30 |
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