EA202092843A1 - Радиофармпрепарат для позитронно-эмиссионной томографии (пэт) для визуализации рецептора макрофагального колониестимулирующего фактора (csf1r) при нейровоспалении - Google Patents
Радиофармпрепарат для позитронно-эмиссионной томографии (пэт) для визуализации рецептора макрофагального колониестимулирующего фактора (csf1r) при нейровоспаленииInfo
- Publication number
- EA202092843A1 EA202092843A1 EA202092843A EA202092843A EA202092843A1 EA 202092843 A1 EA202092843 A1 EA 202092843A1 EA 202092843 A EA202092843 A EA 202092843A EA 202092843 A EA202092843 A EA 202092843A EA 202092843 A1 EA202092843 A1 EA 202092843A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- pet
- stimulating factor
- positron emission
- emission tomography
- radiopharm
- Prior art date
Links
- 238000002600 positron emission tomography Methods 0.000 title abstract 2
- 102000007644 Colony-Stimulating Factors Human genes 0.000 title 2
- 108010071942 Colony-Stimulating Factors Proteins 0.000 title 2
- 230000003959 neuroinflammation Effects 0.000 title 1
- 238000012800 visualization Methods 0.000 title 1
- 101710150918 Macrophage colony-stimulating factor 1 receptor Proteins 0.000 abstract 1
- 102100028198 Macrophage colony-stimulating factor 1 receptor Human genes 0.000 abstract 1
- 208000036110 Neuroinflammatory disease Diseases 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 230000002314 neuroinflammatory effect Effects 0.000 abstract 1
- 229940121896 radiopharmaceutical Drugs 0.000 abstract 1
- 239000012217 radiopharmaceutical Substances 0.000 abstract 1
- 230000002799 radiopharmaceutical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nuclear Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862689958P | 2018-06-26 | 2018-06-26 | |
| PCT/US2019/039234 WO2020006075A1 (en) | 2018-06-26 | 2019-06-26 | Positron emission tomography (pet) radiotracers for imaging macrophage colony-stimulating factor 1 receptor (csf1r) in neuroinflammation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA202092843A1 true EA202092843A1 (ru) | 2021-04-19 |
Family
ID=68985080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA202092843A EA202092843A1 (ru) | 2018-06-26 | 2019-06-26 | Радиофармпрепарат для позитронно-эмиссионной томографии (пэт) для визуализации рецептора макрофагального колониестимулирующего фактора (csf1r) при нейровоспалении |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20210290784A1 (https=) |
| EP (1) | EP3813890A4 (https=) |
| JP (2) | JP2021533087A (https=) |
| KR (1) | KR20210013769A (https=) |
| CN (2) | CN118743770A (https=) |
| AU (1) | AU2019294699B2 (https=) |
| BR (1) | BR112020026602A2 (https=) |
| CA (1) | CA3104520A1 (https=) |
| EA (1) | EA202092843A1 (https=) |
| IL (1) | IL279768B2 (https=) |
| MX (1) | MX2021000141A (https=) |
| WO (1) | WO2020006075A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020132651A1 (en) | 2018-12-20 | 2020-06-25 | Amgen Inc. | Kif18a inhibitors |
| EP3898616B1 (en) | 2018-12-20 | 2024-10-02 | Amgen Inc. | Heteroaryl amides useful as kif18a inhibitors |
| JP7676308B2 (ja) * | 2018-12-20 | 2025-05-14 | アムジエン・インコーポレーテツド | Ｋｉｆ１８ａ阻害剤として有用なヘテロアリールアミド |
| US12540129B2 (en) | 2019-08-02 | 2026-02-03 | Amgen Inc. | KIF18A inhibitors |
| WO2021026099A1 (en) | 2019-08-02 | 2021-02-11 | Amgen Inc. | Kif18a inhibitors |
| EP4269404A4 (en) * | 2020-12-25 | 2024-12-04 | Xizang Haisco Pharmaceutical Co., Ltd. | KETOHEXOKINASE INHIBITORS AND USE THEREOF |
| CA3221884A1 (en) * | 2021-06-11 | 2022-12-15 | Norman Lafrance | Expert scoring system for measurement of severity, treatment response and prognosis of peripheral arterial disease |
| AU2024214768A1 (en) * | 2023-01-30 | 2025-08-07 | The Johns Hopkins University | 18 f-labeled pet radiotracers for imaging macrophage colony stimulating factor 1 receptor |
| CN118027009B (zh) * | 2024-04-15 | 2024-07-12 | 北京师范大学 | 一类靶向于csf1r激酶的苯基酰胺类化合物及其应用 |
| CN119498255B (zh) * | 2024-10-24 | 2025-11-25 | 香港理工大学深圳研究院 | 一种抑郁症小鼠模型及其构建方法与应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006047504A1 (en) * | 2004-10-22 | 2006-05-04 | Janssen Pharmaceutica, N.V. | Aromatic amides as inhibitors of c-fms kinase |
| CN109069666B (zh) * | 2016-04-29 | 2023-04-04 | 纪念斯隆凯特琳癌症中心 | 使靶向颗粒穿透、分布和响应于恶性脑肿瘤中的组合物和方法 |
-
2019
- 2019-06-26 CN CN202410732670.6A patent/CN118743770A/zh active Pending
- 2019-06-26 WO PCT/US2019/039234 patent/WO2020006075A1/en not_active Ceased
- 2019-06-26 AU AU2019294699A patent/AU2019294699B2/en active Active
- 2019-06-26 EA EA202092843A patent/EA202092843A1/ru unknown
- 2019-06-26 MX MX2021000141A patent/MX2021000141A/es unknown
- 2019-06-26 CA CA3104520A patent/CA3104520A1/en active Pending
- 2019-06-26 US US17/253,336 patent/US20210290784A1/en active Pending
- 2019-06-26 EP EP19825817.0A patent/EP3813890A4/en active Pending
- 2019-06-26 CN CN201980056945.6A patent/CN112638431A/zh active Pending
- 2019-06-26 BR BR112020026602-7A patent/BR112020026602A2/pt unknown
- 2019-06-26 JP JP2020571842A patent/JP2021533087A/ja active Pending
- 2019-06-26 KR KR1020217002632A patent/KR20210013769A/ko not_active Ceased
- 2019-06-26 IL IL279768A patent/IL279768B2/en unknown
-
2024
- 2024-06-13 JP JP2024096077A patent/JP2024133496A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020006075A1 (en) | 2020-01-02 |
| EP3813890A4 (en) | 2022-03-23 |
| MX2021000141A (es) | 2021-03-25 |
| KR20210013769A (ko) | 2021-02-05 |
| AU2019294699A1 (en) | 2021-01-21 |
| CN118743770A (zh) | 2024-10-08 |
| IL279768A (en) | 2021-03-01 |
| EP3813890A1 (en) | 2021-05-05 |
| IL279768B2 (en) | 2025-04-01 |
| US20210290784A1 (en) | 2021-09-23 |
| AU2019294699B2 (en) | 2025-05-01 |
| JP2024133496A (ja) | 2024-10-02 |
| JP2021533087A (ja) | 2021-12-02 |
| CN112638431A (zh) | 2021-04-09 |
| CA3104520A1 (en) | 2020-01-02 |
| IL279768B1 (en) | 2024-12-01 |
| BR112020026602A2 (pt) | 2021-03-23 |
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