EA202091713A1 - Биологический синтез аминокислотных цепей для получения пептидов и белков - Google Patents

Биологический синтез аминокислотных цепей для получения пептидов и белков

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Publication number
EA202091713A1
EA202091713A1 EA202091713A EA202091713A EA202091713A1 EA 202091713 A1 EA202091713 A1 EA 202091713A1 EA 202091713 A EA202091713 A EA 202091713A EA 202091713 A EA202091713 A EA 202091713A EA 202091713 A1 EA202091713 A1 EA 202091713A1
Authority
EA
Eurasian Patent Office
Prior art keywords
proteins
amino acid
acid chains
biological synthesis
obtaining peptides
Prior art date
Application number
EA202091713A
Other languages
English (en)
Inventor
Кристоф Кутцнер
Марко Джуман
Original Assignee
Кристоф Кутцнер
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Кристоф Кутцнер filed Critical Кристоф Кутцнер
Publication of EA202091713A1 publication Critical patent/EA202091713A1/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
    • C12N9/506—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses derived from RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Изобретение относится к слитым полипептидам, молекулам нуклеиновых кислот, кодирующим указанные слитые полипептиды, и к генетически модифицированным клеткам, включающим указанные молекулы нуклеиновых кислот. Кроме того, изобретение относится к способу получения целевых полипептидов с использованием слитых полипептидов.
EA202091713A 2018-01-15 2019-01-15 Биологический синтез аминокислотных цепей для получения пептидов и белков EA202091713A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102018200602.4A DE102018200602A1 (de) 2018-01-15 2018-01-15 Biologische Synthese von Aminosäureketten zur Herstellung von Peptiden und Proteinen
PCT/EP2019/050892 WO2019138125A1 (en) 2018-01-15 2019-01-15 Biological synthesis of amino acid chains for preparation of peptides and proteins

Publications (1)

Publication Number Publication Date
EA202091713A1 true EA202091713A1 (ru) 2020-11-25

Family

ID=65138969

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202091713A EA202091713A1 (ru) 2018-01-15 2019-01-15 Биологический синтез аминокислотных цепей для получения пептидов и белков

Country Status (6)

Country Link
US (1) US11697809B2 (ru)
EP (1) EP3740584A1 (ru)
CA (1) CA3087218C (ru)
DE (2) DE102018200602A1 (ru)
EA (1) EA202091713A1 (ru)
WO (1) WO2019138125A1 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3904525A1 (en) 2020-04-27 2021-11-03 Kutzner, Christoph Fusion polypeptides for target peptide production
EP4265636A1 (en) * 2022-04-19 2023-10-25 mk2 Biotechnologies GmbH Preparation of target peptides and proteins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA05011577A (es) * 2003-05-05 2005-12-15 Neose Technologies Inc Purificacion de afinidad a ciclodextrina.
EP2348053A3 (en) 2005-04-26 2011-11-02 Sandoz AG Oligopeptide ligands
AU2011253661B2 (en) 2005-04-26 2013-06-13 Boehringer Ingelheim Rcv Gmbh & Co Kg Production of recombinant proteins by autoproteolytic cleavage of a fusion protein
CN101605809A (zh) 2006-10-31 2009-12-16 善笙生物科技股份有限公司 淀粉吸附区域及其用途
EP2746390A1 (en) 2012-12-19 2014-06-25 Sandoz Ag Method for producing a recombinant protein of interest

Also Published As

Publication number Publication date
DE202019005825U1 (de) 2022-06-07
DE102018200602A1 (de) 2019-07-18
EP3740584A1 (en) 2020-11-25
CA3087218C (en) 2024-04-09
CA3087218A1 (en) 2019-07-18
US11697809B2 (en) 2023-07-11
US20200347373A1 (en) 2020-11-05
WO2019138125A1 (en) 2019-07-18

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