EA201992474A3 - Агонисты 5ht для лечения нарушений - Google Patents
Агонисты 5ht для лечения нарушенийInfo
- Publication number
- EA201992474A3 EA201992474A3 EA201992474A EA201992474A EA201992474A3 EA 201992474 A3 EA201992474 A3 EA 201992474A3 EA 201992474 A EA201992474 A EA 201992474A EA 201992474 A EA201992474 A EA 201992474A EA 201992474 A3 EA201992474 A3 EA 201992474A3
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- agonists
- disorders
- treatment
- treating
- methods
- Prior art date
Links
- 239000000952 serotonin receptor agonist Substances 0.000 title abstract 2
- 230000001037 epileptic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562120726P | 2015-02-25 | 2015-02-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201992474A2 EA201992474A2 (ru) | 2020-02-28 |
| EA201992474A3 true EA201992474A3 (ru) | 2020-05-31 |
Family
ID=56789223
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201992474A EA201992474A3 (ru) | 2015-02-25 | 2016-02-24 | Агонисты 5ht для лечения нарушений |
| EA201791882A EA201791882A1 (ru) | 2015-02-25 | 2016-02-24 | Агонисты 5ht для лечения нарушений |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201791882A EA201791882A1 (ru) | 2015-02-25 | 2016-02-24 | Агонисты 5ht для лечения нарушений |
Country Status (21)
| Country | Link |
|---|---|
| US (5) | US10874643B2 (enExample) |
| EP (4) | EP3632434A1 (enExample) |
| JP (5) | JP6884703B2 (enExample) |
| KR (3) | KR20220048045A (enExample) |
| CN (2) | CN107530326B (enExample) |
| AU (3) | AU2016222804C1 (enExample) |
| BR (1) | BR112017018297B1 (enExample) |
| CA (2) | CA3204599A1 (enExample) |
| CY (1) | CY1125360T1 (enExample) |
| DK (1) | DK3261640T3 (enExample) |
| EA (2) | EA201992474A3 (enExample) |
| ES (2) | ES2920886T3 (enExample) |
| HR (1) | HRP20220822T1 (enExample) |
| HU (1) | HUE059559T2 (enExample) |
| LT (1) | LT3261640T (enExample) |
| PL (1) | PL3261640T3 (enExample) |
| PT (1) | PT3261640T (enExample) |
| RS (1) | RS63426B1 (enExample) |
| SI (1) | SI3261640T1 (enExample) |
| SM (1) | SMT202200276T1 (enExample) |
| WO (1) | WO2016138138A1 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9549909B2 (en) | 2013-05-03 | 2017-01-24 | The Katholieke Universiteit Leuven | Method for the treatment of dravet syndrome |
| SI3261640T1 (sl) | 2015-02-25 | 2022-10-28 | The Regents Of The University Of California | 5HT agonisti za zdravljenje epilepsijskih motenj |
| GB201620095D0 (en) * | 2016-11-28 | 2017-01-11 | Terali Innov Sas And Univ De Strasbourg And Inserm (Inst Nat De La Sante Et De La Rech Medicale) And | Novel use |
| JP2019507111A (ja) | 2015-12-22 | 2019-03-14 | ゾゲニクス インターナショナル リミテッド | 代謝抵抗性フェンフルラミン類縁体およびその使用法 |
| EP3800177B1 (en) | 2015-12-22 | 2025-01-29 | Zogenix International Limited | Fenfluramine compositions and methods of preparing the same |
| RU2021106383A (ru) | 2016-08-24 | 2021-04-05 | Зодженикс Интернэшнл Лимитед | Состав для ингибирования образования агонистов 5-ht2b и способы его применения |
| ES3001152T3 (es) | 2016-12-20 | 2025-03-04 | Lts Lohmann Therapie Systeme Ag | Sistema terapéutico transdérmico que contiene asenapina y polisiloxano o poliisobutileno |
| PL3338768T3 (pl) | 2016-12-20 | 2020-05-18 | Lts Lohmann Therapie-Systeme Ag | Transdermalny system terapeutyczny zawierający asenapinę |
| WO2019002204A1 (en) | 2017-06-26 | 2019-01-03 | Lts Lohmann Therapie-Systeme Ag | TRANSDERMAL THERAPEUTIC SYSTEM CONTAINING ASENAPINE AND SILICONE-TYPE ACRYLIC HYBRID POLYMER |
| US10682317B2 (en) | 2017-09-26 | 2020-06-16 | Zogenix International Limited | Ketogenic diet compatible fenfluramine formulation |
| WO2019216919A1 (en) | 2018-05-11 | 2019-11-14 | Zogenix International Limited | Compositions and methods for treating seizure-induced sudden death |
| EP3806835A1 (en) | 2018-06-14 | 2021-04-21 | Zogenix International Limited | Compositions and methods for treating respiratory depression with fenfluramine |
| EP3810099A1 (en) | 2018-06-20 | 2021-04-28 | LTS Lohmann Therapie-Systeme AG | Transdermal therapeutic system containing asenapine |
| AU2019291060B2 (en) | 2018-06-20 | 2024-09-05 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
| WO2020018839A1 (en) | 2018-07-18 | 2020-01-23 | The Regents Of The University Of California | Compounds and methods for synergistic activation of m channels |
| MX2021000987A (es) * | 2018-07-27 | 2021-06-15 | Xenon Pharmaceuticals Inc | Metodo para tratar la epilepsia. |
| EA202191079A1 (ru) | 2018-11-19 | 2021-09-20 | Зодженикс Интернэшнл Лимитед | Способы лечения синдрома ретта с применением фенфлурамина |
| CN114007692A (zh) * | 2019-05-29 | 2022-02-01 | 加利福尼亚大学董事会 | 治疗癫痫的方法和组合物 |
| EP3791873A1 (en) | 2019-09-16 | 2021-03-17 | Universite De Bordeaux | Methods of treatment and/or prevention of disorders and symptoms related to bkca and/or sk channelophathies |
| BR112022007648A2 (pt) * | 2019-10-23 | 2022-10-11 | Neurocycle Therapeutics Inc | Tratamento de condições epilépticas com moduladores do receptor gabaa |
| SI4048249T1 (sl) * | 2019-10-23 | 2026-04-30 | Maplight Therapeutics, Inc. | Postopki zdravljenja simptomov motnje avtističnega spektra |
| KR20210054684A (ko) | 2019-11-06 | 2021-05-14 | 동국대학교 경주캠퍼스 산학협력단 | 라미나린을 유효성분으로 함유하는 허혈성 뇌혈관 질환 예방용 조성물 |
| CN114828889B (zh) * | 2019-12-06 | 2025-02-14 | 马瑞纳斯制药公司 | 用于治疗结节性硬化症的加奈索酮 |
| KR102476771B1 (ko) * | 2020-05-08 | 2022-12-13 | 광운대학교 산학협력단 | 뇌질환 검증용 eeg 바이오 마커 분석 알고리즘을 통하여 소아 뇌전증 환자 미주신경자극술 효과를 예측하는 방법 |
| US11612574B2 (en) | 2020-07-17 | 2023-03-28 | Zogenix International Limited | Method of treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) |
| MX2023011240A (es) * | 2021-03-25 | 2024-01-12 | Maplight Therapeutics Inc | Composiciones farmaceuticas que comprenden zolmitriptan. |
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| US12599611B2 (en) * | 2021-06-10 | 2026-04-14 | Neurelis, Inc. | Methods and compositions for treating seizure disorders in pediatric patients |
| JP7856338B2 (ja) * | 2021-07-30 | 2026-05-11 | エピジェニクス セラピューティクス インコーポレーテッド | クレミゾール製剤 |
| WO2023107965A1 (en) * | 2021-12-06 | 2023-06-15 | Terran Biosciences, Inc. | Salt and solid forms of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (dom), 2,5-dimethoxy-4-iodoamphetamine (doi), 2,5-dimethoxy-4-bromoamphetamine (dob), and 2,5-dimethoxy-4-chloroamphetamine (doc) |
| US11974992B2 (en) | 2022-01-26 | 2024-05-07 | Neurolixis | Use of serotonin 5-HT1A receptor agonists to treat diseases associated with sudden unexpected death in epilepsy |
| WO2023144166A1 (en) | 2022-01-26 | 2023-08-03 | Neurolixis | Use of serotonin 5-ht1a receptor agonists to treat diseases associated with sudden unexpected death in epilepsy |
| WO2023212244A1 (en) * | 2022-04-27 | 2023-11-02 | Tessellate Therapeutics, Inc. | Methods of treating 5ht2a receptor-mediated conditions |
| IL315086A (en) | 2022-06-09 | 2024-10-01 | Diamond Therapeutics Inc | Amorphous (A-polymorphic) psilocybin |
| US20240174594A1 (en) * | 2022-11-30 | 2024-05-30 | Mind Medicine, Inc. | 4-alkenyl and 4-alkynyl phenethylamine derivatives and related compounds with modified dom-like action |
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| SI3261640T1 (sl) | 2015-02-25 | 2022-10-28 | The Regents Of The University Of California | 5HT agonisti za zdravljenje epilepsijskih motenj |
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-
2016
- 2016-02-24 SI SI201631545T patent/SI3261640T1/sl unknown
- 2016-02-24 ES ES16756282T patent/ES2920886T3/es active Active
- 2016-02-24 AU AU2016222804A patent/AU2016222804C1/en active Active
- 2016-02-24 RS RS20220598A patent/RS63426B1/sr unknown
- 2016-02-24 US US15/552,784 patent/US10874643B2/en active Active
- 2016-02-24 CA CA3204599A patent/CA3204599A1/en active Pending
- 2016-02-24 HR HRP20220822TT patent/HRP20220822T1/hr unknown
- 2016-02-24 WO PCT/US2016/019368 patent/WO2016138138A1/en not_active Ceased
- 2016-02-24 DK DK16756282.6T patent/DK3261640T3/da active
- 2016-02-24 LT LTEPPCT/US2016/019368T patent/LT3261640T/lt unknown
- 2016-02-24 ES ES22157142T patent/ES3060954T3/es active Active
- 2016-02-24 CA CA2977135A patent/CA2977135C/en active Active
- 2016-02-24 KR KR1020227011498A patent/KR20220048045A/ko not_active Ceased
- 2016-02-24 KR KR1020237037303A patent/KR20230152844A/ko active Pending
- 2016-02-24 KR KR1020177026528A patent/KR102385665B1/ko active Active
- 2016-02-24 PT PT167562826T patent/PT3261640T/pt unknown
- 2016-02-24 BR BR112017018297-1A patent/BR112017018297B1/pt active IP Right Grant
- 2016-02-24 SM SM20220276T patent/SMT202200276T1/it unknown
- 2016-02-24 EP EP19211183.9A patent/EP3632434A1/en not_active Withdrawn
- 2016-02-24 EA EA201992474A patent/EA201992474A3/ru unknown
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2019
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