EA201892585A1 - 6-(БУТА-1,3-ДИИН-1-ИЛ)БЕНЗО[d]ТИАЗОЛЬНЫЕ ПРОИЗВОДНЫЕ - Google Patents

6-(БУТА-1,3-ДИИН-1-ИЛ)БЕНЗО[d]ТИАЗОЛЬНЫЕ ПРОИЗВОДНЫЕ

Info

Publication number
EA201892585A1
EA201892585A1 EA201892585A EA201892585A EA201892585A1 EA 201892585 A1 EA201892585 A1 EA 201892585A1 EA 201892585 A EA201892585 A EA 201892585A EA 201892585 A EA201892585 A EA 201892585A EA 201892585 A1 EA201892585 A1 EA 201892585A1
Authority
EA
Eurasian Patent Office
Prior art keywords
diin
buta
benzo
tiazole
derivatives
Prior art date
Application number
EA201892585A
Other languages
English (en)
Inventor
Штефан Дитхельм
Азели Мирре
Филипп Паншо
Кристина Шмитт
Жан-Филипп Сюриве
Original Assignee
Идорсия Фармасьютиклз Лтд
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Идорсия Фармасьютиклз Лтд filed Critical Идорсия Фармасьютиклз Лтд
Publication of EA201892585A1 publication Critical patent/EA201892585A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Изобретение относится к антибактериальным соединениям формулы Iгде группа M и Rимеют значения, указанные в формуле изобретения, и к их солям.
EA201892585A 2016-05-17 2017-05-16 6-(БУТА-1,3-ДИИН-1-ИЛ)БЕНЗО[d]ТИАЗОЛЬНЫЕ ПРОИЗВОДНЫЕ EA201892585A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2016061039 2016-05-17
PCT/EP2017/061689 WO2017198647A1 (en) 2016-05-17 2017-05-16 6-(buta-1,3-diyn-1-yl)benzo[d]thiazole derivatives

Publications (1)

Publication Number Publication Date
EA201892585A1 true EA201892585A1 (ru) 2019-05-31

Family

ID=58772866

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201892585A EA201892585A1 (ru) 2016-05-17 2017-05-16 6-(БУТА-1,3-ДИИН-1-ИЛ)БЕНЗО[d]ТИАЗОЛЬНЫЕ ПРОИЗВОДНЫЕ

Country Status (14)

Country Link
US (1) US20190315731A1 (ru)
EP (1) EP3458453A1 (ru)
JP (1) JP2019516723A (ru)
KR (1) KR20190009324A (ru)
CN (1) CN109153673A (ru)
AR (1) AR108488A1 (ru)
AU (1) AU2017267194A1 (ru)
BR (1) BR112018073580A2 (ru)
CA (1) CA3024756A1 (ru)
EA (1) EA201892585A1 (ru)
MA (1) MA45024A (ru)
MX (1) MX2018014170A (ru)
TW (1) TW201741308A (ru)
WO (1) WO2017198647A1 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR105646A1 (es) 2015-08-11 2017-10-25 Actelion Pharmaceuticals Ltd Agentes antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituida
AR105889A1 (es) 2015-09-03 2017-11-22 Actelion Pharmaceuticals Ltd Compuestos antibacterianos 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituidos

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2774250C (en) * 2009-10-13 2013-12-17 Pfizer Inc. C-linked hydroxamic acid derivatives useful as antibacterial agents
CA2782453C (en) * 2009-12-16 2015-11-24 Matthew Frank Brown N-linked hydroxamic acid derivatives useful as antibacterial agents
EP2694481B1 (en) * 2011-04-08 2015-12-30 Pfizer Inc Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents
AR097617A1 (es) * 2013-09-13 2016-04-06 Actelion Pharmaceuticals Ltd Derivados antibacterianos del 2h-indazol
SG11201605014YA (en) * 2013-12-19 2016-07-28 Actelion Pharmaceuticals Ltd Antibacterial 1h-indazole and 1h-indole derivatives
TW201625569A (zh) * 2014-11-19 2016-07-16 艾克泰聯製藥有限公司 抗菌性苯并噻唑衍生物

Also Published As

Publication number Publication date
KR20190009324A (ko) 2019-01-28
AU2017267194A1 (en) 2019-01-17
CA3024756A1 (en) 2017-11-23
US20190315731A1 (en) 2019-10-17
BR112018073580A2 (pt) 2019-03-19
JP2019516723A (ja) 2019-06-20
TW201741308A (zh) 2017-12-01
MX2018014170A (es) 2019-03-14
EP3458453A1 (en) 2019-03-27
MA45024A (fr) 2019-03-27
WO2017198647A1 (en) 2017-11-23
CN109153673A (zh) 2019-01-04
AR108488A1 (es) 2018-08-22

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