BR112018073580A2 - derivados de 6-(buta-1,3-diyn-1-il) benzo [d] tiazol - Google Patents

derivados de 6-(buta-1,3-diyn-1-il) benzo [d] tiazol

Info

Publication number
BR112018073580A2
BR112018073580A2 BR112018073580-9A BR112018073580A BR112018073580A2 BR 112018073580 A2 BR112018073580 A2 BR 112018073580A2 BR 112018073580 A BR112018073580 A BR 112018073580A BR 112018073580 A2 BR112018073580 A2 BR 112018073580A2
Authority
BR
Brazil
Prior art keywords
diyn
buta
benzo
thiazole derivatives
thiazole
Prior art date
Application number
BR112018073580-9A
Other languages
English (en)
Inventor
DIETHELM Stefan
Mirre Azely
Panchaud Philippe
Schmitt Christine
Surivet Jean-Philippe
Specklin Jean-Luc (Falecido)
Original Assignee
Idorsia Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idorsia Pharmaceuticals Ltd filed Critical Idorsia Pharmaceuticals Ltd
Publication of BR112018073580A2 publication Critical patent/BR112018073580A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

a invenção refere-se aos compostos antibacterianos da fórmula i i em que o grupo m e r1 são tais como definidos nas reivindicações, bem como os seus sais.
BR112018073580-9A 2016-05-17 2017-05-16 derivados de 6-(buta-1,3-diyn-1-il) benzo [d] tiazol BR112018073580A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP2016061039 2016-05-17
EPPCT/EP2016/061039 2016-05-17
PCT/EP2017/061689 WO2017198647A1 (en) 2016-05-17 2017-05-16 6-(buta-1,3-diyn-1-yl)benzo[d]thiazole derivatives

Publications (1)

Publication Number Publication Date
BR112018073580A2 true BR112018073580A2 (pt) 2019-03-19

Family

ID=58772866

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018073580-9A BR112018073580A2 (pt) 2016-05-17 2017-05-16 derivados de 6-(buta-1,3-diyn-1-il) benzo [d] tiazol

Country Status (14)

Country Link
US (1) US20190315731A1 (pt)
EP (1) EP3458453A1 (pt)
JP (1) JP2019516723A (pt)
KR (1) KR20190009324A (pt)
CN (1) CN109153673A (pt)
AR (1) AR108488A1 (pt)
AU (1) AU2017267194A1 (pt)
BR (1) BR112018073580A2 (pt)
CA (1) CA3024756A1 (pt)
EA (1) EA201892585A1 (pt)
MA (1) MA45024A (pt)
MX (1) MX2018014170A (pt)
TW (1) TW201741308A (pt)
WO (1) WO2017198647A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR105646A1 (es) 2015-08-11 2017-10-25 Actelion Pharmaceuticals Ltd Agentes antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituida
AR105889A1 (es) 2015-09-03 2017-11-22 Actelion Pharmaceuticals Ltd Compuestos antibacterianos 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituidos

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2488489A2 (en) * 2009-10-13 2012-08-22 Pfizer Inc. C-linked hydroxamic acid derivatives useful as antibacterial agents
CA2782453C (en) * 2009-12-16 2015-11-24 Matthew Frank Brown N-linked hydroxamic acid derivatives useful as antibacterial agents
CA2830866A1 (en) * 2011-04-08 2012-10-11 Pfizer Inc. Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents
AR097617A1 (es) * 2013-09-13 2016-04-06 Actelion Pharmaceuticals Ltd Derivados antibacterianos del 2h-indazol
EP3083567B1 (en) * 2013-12-19 2018-03-07 Idorsia Pharmaceuticals Ltd Antibacterial 1h-indazole and 1h-indole derivatives
AR102687A1 (es) * 2014-11-19 2017-03-15 Actelion Pharmaceuticals Ltd Derivados de benzotiazol antibacterianos

Also Published As

Publication number Publication date
CA3024756A1 (en) 2017-11-23
EP3458453A1 (en) 2019-03-27
KR20190009324A (ko) 2019-01-28
JP2019516723A (ja) 2019-06-20
CN109153673A (zh) 2019-01-04
MX2018014170A (es) 2019-03-14
MA45024A (fr) 2019-03-27
US20190315731A1 (en) 2019-10-17
AR108488A1 (es) 2018-08-22
EA201892585A1 (ru) 2019-05-31
AU2017267194A1 (en) 2019-01-17
WO2017198647A1 (en) 2017-11-23
TW201741308A (zh) 2017-12-01

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]