EA201891651A2 - Фармацевтическая композиция для профилактики алиментарного ожирения - Google Patents
Фармацевтическая композиция для профилактики алиментарного ожиренияInfo
- Publication number
- EA201891651A2 EA201891651A2 EA201891651A EA201891651A EA201891651A2 EA 201891651 A2 EA201891651 A2 EA 201891651A2 EA 201891651 A EA201891651 A EA 201891651A EA 201891651 A EA201891651 A EA 201891651A EA 201891651 A2 EA201891651 A2 EA 201891651A2
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- obesity
- prevention
- composition
- pharmaceutical composition
- alimentary obesity
- Prior art date
Links
- 208000008589 Obesity Diseases 0.000 title abstract 4
- 235000020824 obesity Nutrition 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 4
- 208000008338 non-alcoholic fatty liver disease Diseases 0.000 abstract 3
- 206010053219 non-alcoholic steatohepatitis Diseases 0.000 abstract 2
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 230000037396 body weight Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- BOWVQLFMWHZBEF-KTKRTIGZSA-N oleoyl ethanolamide Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)NCCO BOWVQLFMWHZBEF-KTKRTIGZSA-N 0.000 abstract 1
- 239000011885 synergistic combination Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Child & Adolescent Psychology (AREA)
- Botany (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Настоящее изобретение относится к фармацевтической композиции/составу для профилактики алиментарного ожирения. Более конкретно, изобретение относится к композиции/составу, содержащему синергетическую комбинацию олеоилэтаноламида (ОЭА) и других натуральных ингредиентов, который может быть применен для лечения ожирения и сопутствующих ему нарушений, связанных с жировым обменом, таких как неалкогольный стеатогепатит (НАСГ), неалкогольная жировая болезнь печени (НАЖБП). Оно также может быть полезно при борьбе с ожирением путем поддержания веса тела. Изобретением также обеспечены различные составы и способы их получения.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN201721029447 | 2017-08-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201891651A2 true EA201891651A2 (ru) | 2019-02-28 |
EA201891651A3 EA201891651A3 (ru) | 2019-05-31 |
Family
ID=63244444
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201891651A EA201891651A3 (ru) | 2017-08-19 | 2018-08-16 | Фармацевтическая композиция для профилактики алиментарного ожирения |
Country Status (18)
Country | Link |
---|---|
US (1) | US10702487B2 (ru) |
EP (1) | EP3443987B1 (ru) |
CA (1) | CA3012675C (ru) |
CY (1) | CY1124010T1 (ru) |
DK (1) | DK3443987T3 (ru) |
EA (1) | EA201891651A3 (ru) |
ES (1) | ES2864136T3 (ru) |
HR (1) | HRP20210466T1 (ru) |
HU (1) | HUE053678T2 (ru) |
LT (1) | LT3443987T (ru) |
MY (1) | MY177974A (ru) |
PH (1) | PH12018000207A1 (ru) |
PL (1) | PL3443987T3 (ru) |
PT (1) | PT3443987T (ru) |
RS (1) | RS61628B1 (ru) |
SG (1) | SG10201806472SA (ru) |
SI (1) | SI3443987T1 (ru) |
UA (1) | UA122710C2 (ru) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2021041495A2 (en) * | 2019-08-26 | 2021-03-04 | The Trustees Of Indiana University | Method to maintain or enhance tissue |
CN111084301B (zh) * | 2019-12-30 | 2023-08-22 | 内江师范学院 | 一种桑叶提取物鱼饲料粘合剂及制备方法和应用 |
CN113712206A (zh) * | 2021-09-16 | 2021-11-30 | 湖南希尔天然药业有限公司 | 一种含有桑叶dnj和桑叶肽的组合物及其制备方法 |
CA3242396A1 (en) * | 2021-12-13 | 2023-06-22 | The Regents Of The University Of California | Method of treating liver steatosis with bioavailable formulation of oleoylethanolamide |
WO2023250211A2 (en) * | 2022-06-24 | 2023-12-28 | Veroscience Llc | Treatment of non-alcoholic steatohepatitis and non-alcoholic fatty liver disease |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4042687A (en) * | 1975-11-24 | 1977-08-16 | Control Drug, Inc. | Method of treating obesity by the oral administration of a predigested protein composition |
US20050054730A1 (en) * | 2001-03-27 | 2005-03-10 | The Regents Of The University Of California | Compounds, compositions and treatment of oleoylethanolamide-like modulators of PPARalpha |
CA2442683A1 (en) | 2001-03-27 | 2002-10-17 | The Regents Of The University Of California | Methods, compounds, and compositions for reducing body fat and modulating fatty acid metabolism |
AU2003296895A1 (en) | 2002-08-20 | 2004-05-04 | The Regents Of The University Of California | Combination therapy for controlling appetites |
WO2004045307A2 (en) | 2002-11-18 | 2004-06-03 | Natural Asa | Dietry supplements and foods product comprising oleylethanolamide |
WO2004078113A2 (en) | 2003-03-04 | 2004-09-16 | Pharmacia Corporation | Treatment and prevention of obesity with cox-2 inhibitors alone or in combination with weight-loss agents |
EP1677780A4 (en) | 2003-10-16 | 2007-05-02 | Univ California | DIETETIC COMPOSITIONS AND OTHER COMPOSITIONS, COMPOUNDS AND METHODS FOR ORGANIC LIPID REDUCTION, APPETILE CONTROL, AND METABOLISM MODULATION OF FATTY ACIDS |
US20090054526A1 (en) | 2005-07-14 | 2009-02-26 | Hansen Harald S | Inhibitors of anorexic lipid hydrolysis for the treatment of eating disorders |
WO2009093737A1 (ja) * | 2008-01-25 | 2009-07-30 | Kobayashi Pharmaceutical Co., Ltd. | 抗肥満用医薬組成物 |
MX2010012682A (es) | 2008-05-19 | 2010-12-15 | Nestec Sa | Metodos para reducir la absorcion de lipidos por un animal. |
WO2012015704A2 (en) | 2010-07-28 | 2012-02-02 | The Regents Of The University Of California | Peripherally restricted faah inhibitors |
WO2012090225A2 (en) | 2010-12-29 | 2012-07-05 | Nutracryst Therapeutics Private Limited | Novel cocrystals / molecular salts of metformin with oleoylethanolamide as an effective anti-diabetic + anti- obesity agent |
BR112013028723A2 (pt) | 2011-05-10 | 2016-08-09 | Nestec Sa | métodos e composições para promover o crescimento da massa corporal magra |
MX354772B (es) | 2011-08-19 | 2018-03-21 | Univ California | Inhibidores de la amida de acidos grasos (faah) restringidos perifericamente por bifenil metasustituido. |
CN102579414A (zh) | 2012-01-29 | 2012-07-18 | 厦门大学 | 油酰乙醇胺作为降血脂、防治非酒精性脂肪肝药物的用途 |
DK2890684T3 (en) | 2012-07-24 | 2018-05-07 | Bial Portela & Ca Sa | URINARY COMPOUNDS AND THEIR USE AS ENZYMINE INHIBITORS |
WO2014037546A1 (en) | 2012-09-07 | 2014-03-13 | Nestec S.A. | Oleoylethanolamide compositions |
ITMI20131180A1 (it) | 2013-07-15 | 2015-01-16 | Fond Istituto Italiano Di Tecnologia | O-alchil triazolil carbammati come inibitori di idrolasi delle ammidi degli acidi grassi (faah) |
RU2693457C2 (ru) | 2013-07-18 | 2019-07-03 | Фондацьоне Иституто Итальяно Ди Текнолоджия | Фенилкарбаматы и их применения в качестве ингибиторов фермента гидролазы амидов жирных кислот (faah) и модуляторов d3 допаминового рецептора (d3dr) |
HUE033615T2 (hu) | 2013-07-24 | 2017-12-28 | Bial - Portela & Ca S A | Imidazol-karboxamidok, és FAAH inhibitorként történõ alkalmazásuk |
CN105593226A (zh) | 2013-08-01 | 2016-05-18 | 比亚尔-珀特拉和Ca股份公司 | 脲类化合物及其作为faah酶抑制剂的用途 |
WO2015157313A1 (en) | 2014-04-07 | 2015-10-15 | The Regents Of The University Of California | Inhibitors of fatty acid amide hydrolase (faah) enzyme with improved oral bioavailability and their use as medicaments |
IL305528A (en) | 2015-05-21 | 2023-10-01 | Scisparc Ltd | Combinations of opioids and acylethnoamines |
WO2017025588A1 (en) | 2015-08-11 | 2017-02-16 | Eyesiu Medicines B.V. | Pegylated lipid nanoparticle with bioactive lipophilic compound |
-
2018
- 2018-07-26 US US16/046,482 patent/US10702487B2/en active Active
- 2018-07-27 MY MYPI2018702652A patent/MY177974A/en unknown
- 2018-07-27 CA CA3012675A patent/CA3012675C/en active Active
- 2018-07-30 SG SG10201806472SA patent/SG10201806472SA/en unknown
- 2018-07-31 PH PH12018000207A patent/PH12018000207A1/en unknown
- 2018-08-13 ES ES18188634T patent/ES2864136T3/es active Active
- 2018-08-13 PT PT181886342T patent/PT3443987T/pt unknown
- 2018-08-13 SI SI201830245T patent/SI3443987T1/sl unknown
- 2018-08-13 RS RS20210359A patent/RS61628B1/sr unknown
- 2018-08-13 EP EP18188634.2A patent/EP3443987B1/en active Active
- 2018-08-13 LT LTEP18188634.2T patent/LT3443987T/lt unknown
- 2018-08-13 HU HUE18188634A patent/HUE053678T2/hu unknown
- 2018-08-13 PL PL18188634T patent/PL3443987T3/pl unknown
- 2018-08-13 DK DK18188634.2T patent/DK3443987T3/da active
- 2018-08-16 EA EA201891651A patent/EA201891651A3/ru unknown
- 2018-08-16 UA UAA201808780A patent/UA122710C2/uk unknown
-
2021
- 2021-03-19 HR HRP20210466TT patent/HRP20210466T1/hr unknown
- 2021-03-23 CY CY20211100251T patent/CY1124010T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
PH12018000207B1 (en) | 2019-06-03 |
CA3012675A1 (en) | 2019-02-19 |
EA201891651A3 (ru) | 2019-05-31 |
PT3443987T (pt) | 2021-03-18 |
CA3012675C (en) | 2021-06-15 |
CY1124010T1 (el) | 2022-05-27 |
PH12018000207A1 (en) | 2019-06-03 |
BR102018016746A2 (pt) | 2019-03-26 |
MY177974A (en) | 2020-09-28 |
BR102018016746A8 (pt) | 2023-02-14 |
EP3443987A1 (en) | 2019-02-20 |
LT3443987T (lt) | 2021-04-26 |
RS61628B1 (sr) | 2021-04-29 |
SG10201806472SA (en) | 2019-03-28 |
EP3443987B1 (en) | 2020-12-23 |
PL3443987T3 (pl) | 2021-08-02 |
HRP20210466T1 (hr) | 2021-05-14 |
SI3443987T1 (sl) | 2021-07-30 |
UA122710C2 (uk) | 2020-12-28 |
US20190054046A1 (en) | 2019-02-21 |
US10702487B2 (en) | 2020-07-07 |
DK3443987T3 (da) | 2021-03-22 |
ES2864136T3 (es) | 2021-10-13 |
HUE053678T2 (hu) | 2021-07-28 |
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