BRPI0819690B8 - uso de uma composição compreendendo cisteamina ou cistamina, ou um sal farmaceuticamente aceitável das mesmas - Google Patents

uso de uma composição compreendendo cisteamina ou cistamina, ou um sal farmaceuticamente aceitável das mesmas

Info

Publication number
BRPI0819690B8
BRPI0819690B8 BRPI0819690A BRPI0819690A BRPI0819690B8 BR PI0819690 B8 BRPI0819690 B8 BR PI0819690B8 BR PI0819690 A BRPI0819690 A BR PI0819690A BR PI0819690 A BRPI0819690 A BR PI0819690A BR PI0819690 B8 BRPI0819690 B8 BR PI0819690B8
Authority
BR
Brazil
Prior art keywords
cysteamine
cystamine
composition
pharmaceutically acceptable
acceptable salt
Prior art date
Application number
BRPI0819690A
Other languages
English (en)
Inventor
Schneider Jerry
Dohil Ranjan
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40679016&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0819690(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ California filed Critical Univ California
Publication of BRPI0819690A2 publication Critical patent/BRPI0819690A2/pt
Publication of BRPI0819690B1 publication Critical patent/BRPI0819690B1/pt
Publication of BRPI0819690B8 publication Critical patent/BRPI0819690B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

uso de um produto de cisteamina, e, de uma composição compreendendo cisteamina ou cistamina, ou um sal farmaceuticamente aceitável das mesmas. a revelação, no geral, diz respeito ao tratamento de desordens de gordura no fígado compreendendo administrar composições compreendendo produtos de cisteamina. a revelação fornece administração de composições de cisteamina entericamente revestidas para tratar desordens de gordura no fígado, tais como doença do fígado gorduroso não alcoólica (nafld) e esteatohepatite não alcoólica (nash).
BRPI0819690A 2007-11-30 2008-11-28 uso de uma composição compreendendo cisteamina ou cistamina, ou um sal farmaceuticamente aceitável das mesmas BRPI0819690B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US99151707P 2007-11-30 2007-11-30
US60/991517 2007-11-30
US8539708P 2008-07-31 2008-07-31
US61/085397 2008-07-31
PCT/US2008/085064 WO2009070781A1 (en) 2007-11-30 2008-11-28 Methods of treating non-alcoholic steatohepatitis (nash) using cysteamine products

Publications (3)

Publication Number Publication Date
BRPI0819690A2 BRPI0819690A2 (pt) 2014-10-07
BRPI0819690B1 BRPI0819690B1 (pt) 2019-07-30
BRPI0819690B8 true BRPI0819690B8 (pt) 2021-05-25

Family

ID=40679016

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0819690A BRPI0819690B8 (pt) 2007-11-30 2008-11-28 uso de uma composição compreendendo cisteamina ou cistamina, ou um sal farmaceuticamente aceitável das mesmas

Country Status (26)

Country Link
US (5) US7994226B2 (pt)
EP (2) EP2636404B1 (pt)
JP (3) JP5583022B2 (pt)
KR (1) KR20100091219A (pt)
CN (2) CN101932238B (pt)
AR (1) AR069500A1 (pt)
AU (1) AU2008329628B2 (pt)
BR (1) BRPI0819690B8 (pt)
CA (1) CA2706768C (pt)
CL (1) CL2008003582A1 (pt)
CY (1) CY1114126T1 (pt)
DK (1) DK2214480T3 (pt)
ES (1) ES2417179T3 (pt)
HK (1) HK1141945A1 (pt)
HR (1) HRP20130590T1 (pt)
IL (2) IL205909B (pt)
MX (2) MX2010005921A (pt)
MY (1) MY156316A (pt)
NZ (1) NZ585732A (pt)
PL (1) PL2214480T3 (pt)
PT (1) PT2214480E (pt)
RU (1) RU2498795C2 (pt)
SG (1) SG10201403200RA (pt)
TW (2) TWI535435B (pt)
WO (1) WO2009070781A1 (pt)
ZA (1) ZA201003670B (pt)

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AR096628A1 (es) * 2013-06-17 2016-01-20 Raptor Pharmaceuticals Inc Formulación en perlas de cisteamina de liberación retardada y métodos de preparación y uso de ella
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WO2017087532A1 (en) * 2015-11-16 2017-05-26 The Regents Of The University Of California Methods of treating non-alcoholic steatohepatitis (nash) using cysteamine compounds
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CN117599029A (zh) 2016-03-17 2024-02-27 硫创治疗公司 用于控制释放半胱胺和系统治疗半胱胺敏感性病症的组合物
ITUA20161799A1 (it) * 2016-03-18 2017-09-18 Recordati Ind Chimica E Farmaceutica S P A Composizione farmaceutica a rilascio prolungato comprendente cisteamina o un suo sale
AU2018282124B2 (en) * 2017-06-08 2024-09-19 N-Gene Research Laboratories, Inc. Methods for treating NASH and for preventing NASH-induced HCC
US10632092B2 (en) 2017-08-30 2020-04-28 First Fruits Business Ministry, Llc Composition for and method to increase serum adiponectin and reduce body fat
EP3684418A4 (en) * 2017-09-20 2021-06-16 Thiogenesis Therapeutics, Inc. TREATMENT METHODS FOR CYSTEAMINE SENSITIVE CONDITIONS
KR102177304B1 (ko) * 2018-07-23 2020-11-10 제이투에이치바이오텍 (주) 비알콜성 지방간염의 예방 또는 치료용 약학 조성물
CN111544426A (zh) * 2019-02-12 2020-08-18 复旦大学 炔丙基半胱氨酸及其在制备新靶点药物中的用途
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Also Published As

Publication number Publication date
AR069500A1 (es) 2010-01-27
BRPI0819690A2 (pt) 2014-10-07
PT2214480E (pt) 2013-07-23
US20130183351A1 (en) 2013-07-18
PL2214480T3 (pl) 2013-11-29
JP2014237670A (ja) 2014-12-18
IL205909A0 (en) 2010-11-30
US20100303870A1 (en) 2010-12-02
AU2008329628A1 (en) 2009-06-04
JP2017165735A (ja) 2017-09-21
EP2636404B1 (en) 2019-03-20
CA2706768C (en) 2016-06-28
BRPI0819690B1 (pt) 2019-07-30
CA2706768A1 (en) 2009-06-04
US9511038B2 (en) 2016-12-06
EP2636404A3 (en) 2013-10-16
MX360827B (es) 2018-11-16
CL2008003582A1 (es) 2009-04-03
JP2011505375A (ja) 2011-02-24
EP2636404A2 (en) 2013-09-11
TWI535435B (zh) 2016-06-01
CN101932238A (zh) 2010-12-29
HRP20130590T1 (en) 2013-08-31
CN104825430A (zh) 2015-08-12
CN104825430B (zh) 2018-05-04
HK1141945A1 (en) 2010-11-26
US9149448B2 (en) 2015-10-06
ES2417179T3 (es) 2013-08-06
SG10201403200RA (en) 2014-10-30
CN101932238B (zh) 2015-04-08
TWI478710B (zh) 2015-04-01
KR20100091219A (ko) 2010-08-18
IL254586A0 (en) 2017-11-30
US20120015005A1 (en) 2012-01-19
JP5583022B2 (ja) 2014-09-03
WO2009070781A1 (en) 2009-06-04
CY1114126T1 (el) 2016-07-27
EP2214480A4 (en) 2010-09-29
NZ585732A (en) 2012-02-24
US10307386B2 (en) 2019-06-04
ZA201003670B (en) 2011-08-31
DK2214480T3 (da) 2013-07-08
US20170304233A1 (en) 2017-10-26
EP2214480B1 (en) 2013-03-27
US8263662B2 (en) 2012-09-11
EP2214480A1 (en) 2010-08-11
AU2008329628B2 (en) 2014-06-26
RU2010126631A (ru) 2012-01-10
JP6121951B2 (ja) 2017-04-26
MY156316A (en) 2016-02-11
RU2498795C2 (ru) 2013-11-20
IL205909B (en) 2018-05-31
TW200927093A (en) 2009-07-01
US7994226B2 (en) 2011-08-09
MX2010005921A (es) 2010-06-11
US20160143865A1 (en) 2016-05-26
TW201513855A (zh) 2015-04-16

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