EA201791907A1 - Бивалентная вакцина против вируса свиного гриппа - Google Patents

Бивалентная вакцина против вируса свиного гриппа

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Publication number
EA201791907A1
EA201791907A1 EA201791907A EA201791907A EA201791907A1 EA 201791907 A1 EA201791907 A1 EA 201791907A1 EA 201791907 A EA201791907 A EA 201791907A EA 201791907 A EA201791907 A EA 201791907A EA 201791907 A1 EA201791907 A1 EA 201791907A1
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EA
Eurasian Patent Office
Prior art keywords
flu virus
swine flu
subject
vaccine against
bivalent vaccine
Prior art date
Application number
EA201791907A
Other languages
English (en)
Inventor
Марк Аллан Айхмайер
Уэсли Скотт Джонсон
Эрик Мартин Вон
Мишель Л. Вальц
Original Assignee
Бёрингер Ингельхайм Ветмедика Гмбх
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Application filed by Бёрингер Ингельхайм Ветмедика Гмбх filed Critical Бёрингер Ингельхайм Ветмедика Гмбх
Publication of EA201791907A1 publication Critical patent/EA201791907A1/ru

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    • C—CHEMISTRY; METALLURGY
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Abstract

Изобретение относится к иммуногенной композиции, которая включает: a) модифицированный живой H3 вирус свиного гриппа и b) модифицированный живой H1 вирус свиного гриппа. Кроме того, данное изобретение относится к способам иммунизации субъекта, который включает введение такому субъекту иммуногенной композиции в соответствии с настоящим изобретением. Более того, настоящее изобретение относится к способам лечения или предотвращения клинических признаков, вызванных вирусом свиного гриппа у субъекта, который в этом нуждается, где способ включает введение субъекту терапевтически эффективного количества иммуногенной композиции в соответствии с настоящим изобретением.
EA201791907A 2015-02-26 2016-02-23 Бивалентная вакцина против вируса свиного гриппа EA201791907A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562121181P 2015-02-26 2015-02-26
PCT/US2016/019037 WO2016137929A1 (en) 2015-02-26 2016-02-23 Bivalent swine influenza virus vaccine

Publications (1)

Publication Number Publication Date
EA201791907A1 true EA201791907A1 (ru) 2018-02-28

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EA201791907A EA201791907A1 (ru) 2015-02-26 2016-02-23 Бивалентная вакцина против вируса свиного гриппа

Country Status (13)

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US (2) US10029005B2 (ru)
EP (1) EP3261664A1 (ru)
JP (1) JP6722686B2 (ru)
KR (1) KR20170122786A (ru)
CN (1) CN107250353B (ru)
AU (1) AU2016222962B2 (ru)
BR (1) BR112017015789A2 (ru)
CL (2) CL2017001961A1 (ru)
EA (1) EA201791907A1 (ru)
MX (1) MX2017010908A (ru)
PH (1) PH12017501370A1 (ru)
TW (1) TWI711462B (ru)
WO (1) WO2016137929A1 (ru)

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BR122015032743B1 (pt) 2004-06-01 2018-04-03 Mount Sinai School Of Medicine Of New York University Vírus atenuado de influenza de suínos geneticamente engenheirado, formulação imunogênica, formulação farmacêutica, seus usos e métodos para produzir uma vacina
EA201791907A1 (ru) 2015-02-26 2018-02-28 Бёрингер Ингельхайм Ветмедика Гмбх Бивалентная вакцина против вируса свиного гриппа
WO2019121513A1 (en) * 2017-12-18 2019-06-27 Intervet International B.V. Swine influenza a virus vaccine
CN111630190A (zh) * 2017-12-20 2020-09-04 勃林格殷格翰动物保健有限公司 经修饰的活猪流感病毒疫苗的检测
BR112021005255A2 (pt) * 2018-09-21 2021-06-29 Board Of Regents Of The University Of Nebraska método de produção e uso de genes para vacina contra a influenza centralizada universal
JP7350864B2 (ja) * 2018-10-31 2023-09-26 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー 異種スパイクタンパク質を有するｈ５２ ｉｂｖワクチン
EA202191145A1 (ru) * 2018-10-31 2021-08-23 Бёрингер Ингельхайм Ветмедика Гмбх Вакцина виб 4/91 с гетерологичным шиповидным белком
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EP3261664A1 (en) 2018-01-03
KR20170122786A (ko) 2017-11-06
CN107250353A (zh) 2017-10-13
TWI711462B (zh) 2020-12-01
TW201701900A (zh) 2017-01-16
WO2016137929A1 (en) 2016-09-01
AU2016222962A1 (en) 2017-07-13
US20160250318A1 (en) 2016-09-01
PH12017501370A1 (en) 2017-12-18
US20180289795A1 (en) 2018-10-11
CN107250353B (zh) 2021-07-23
CL2017001961A1 (es) 2018-04-20
JP6722686B2 (ja) 2020-07-15
JP2018512388A (ja) 2018-05-17
CL2018002692A1 (es) 2019-01-18
AU2016222962B2 (en) 2020-05-21
US10029005B2 (en) 2018-07-24
US10905756B2 (en) 2021-02-02
BR112017015789A2 (pt) 2018-03-27
MX2017010908A (es) 2017-12-07

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