EA201790696A1 - Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточности - Google Patents
Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточностиInfo
- Publication number
- EA201790696A1 EA201790696A1 EA201790696A EA201790696A EA201790696A1 EA 201790696 A1 EA201790696 A1 EA 201790696A1 EA 201790696 A EA201790696 A EA 201790696A EA 201790696 A EA201790696 A EA 201790696A EA 201790696 A1 EA201790696 A1 EA 201790696A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- kidney damage
- compositions
- methods
- prediction
- diagnosis
- Prior art date
Links
- 210000003734 kidney Anatomy 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 208000001647 Renal Insufficiency Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 201000006370 kidney failure Diseases 0.000 title 1
- 102000001902 CC Chemokines Human genes 0.000 abstract 1
- 108010040471 CC Chemokines Proteins 0.000 abstract 1
- 101150064697 CXCL16 gene Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 108010023337 axl receptor tyrosine kinase Proteins 0.000 abstract 1
- 239000000104 diagnostic biomarker Substances 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 239000000092 prognostic biomarker Substances 0.000 abstract 1
- 102000027426 receptor tyrosine kinases Human genes 0.000 abstract 1
- 238000011269 treatment regimen Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/521—Chemokines
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462066310P | 2014-10-20 | 2014-10-20 | |
| US201462066313P | 2014-10-20 | 2014-10-20 | |
| US201462066316P | 2014-10-20 | 2014-10-20 | |
| PCT/US2015/056462 WO2016064877A2 (en) | 2014-10-20 | 2015-10-20 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201790696A1 true EA201790696A1 (ru) | 2017-10-31 |
Family
ID=55761743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201790696A EA201790696A1 (ru) | 2014-10-20 | 2015-10-20 | Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточности |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11333671B2 (https=) |
| EP (2) | EP3210018B1 (https=) |
| JP (4) | JP6792553B2 (https=) |
| KR (1) | KR102431003B1 (https=) |
| CN (2) | CN110702921B (https=) |
| AU (2) | AU2015336069B2 (https=) |
| BR (1) | BR112017008218A2 (https=) |
| CA (1) | CA2965153C (https=) |
| EA (1) | EA201790696A1 (https=) |
| ES (1) | ES2907551T3 (https=) |
| MX (1) | MX388231B (https=) |
| PT (1) | PT3210018T (https=) |
| WO (1) | WO2016064877A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2965153C (en) | 2014-10-20 | 2023-10-24 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP4063853A1 (en) * | 2017-01-12 | 2022-09-28 | Astute Medical, Inc. | Methods and compositions for evaluation and treatment of renal injury and renal failure based on c-c motif chemokine ligand 14 measurement |
| CN110431422A (zh) | 2017-02-06 | 2019-11-08 | 机敏医药股份有限公司 | 用于肾损伤和肾衰竭的诊断和预后的方法和组合物 |
| US11891439B2 (en) | 2017-12-28 | 2024-02-06 | Astute Medical, Inc. | Antibodies and assays for CCL14 |
| US12114978B2 (en) | 2018-04-02 | 2024-10-15 | Potrero Medical, Inc. | Systems, devices and methods for draining and analyzing bodily fluids and assessing health |
| CN119454032A (zh) * | 2018-04-02 | 2025-02-18 | 波特雷罗医疗公司 | 用于排出和分析体液并评估健康的系统、设备和方法 |
| CN114207436A (zh) * | 2019-05-24 | 2022-03-18 | 机敏医药股份有限公司 | 基于c-c基序趋化因子配体14测量而评估和治疗肾损伤的方法 |
| US20230290457A1 (en) * | 2020-03-23 | 2023-09-14 | Biocogniv Inc. | Artificial intelligence medical device |
| GB2596142B (en) * | 2020-06-19 | 2023-11-29 | Secr Defence | Methods and associated uses, kits and systems for assessing sepsis |
| EP4247395A4 (en) * | 2020-11-18 | 2024-09-18 | Astute Medical, Inc. | Methods and compositions for treatment of renal injury and renal failure |
| CA3253529A1 (en) * | 2022-03-03 | 2023-09-07 | Astute Medical, Inc. | METHODS AND COMPOSITIONS FOR EVALUATING AND TREATING PERSISTENT ACUTE RENAL INJURY BASED ON A C-C MOTIFYING CHEMOKIN LIGAND MEASUREMENT 14 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5028535A (en) | 1989-01-10 | 1991-07-02 | Biosite Diagnostics, Inc. | Threshold ligand-receptor assay |
| US5939272A (en) | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
| US5922615A (en) | 1990-03-12 | 1999-07-13 | Biosite Diagnostics Incorporated | Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network |
| CA2072758A1 (en) | 1990-09-14 | 1992-03-15 | Kenneth Francis Buechler | Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays |
| US5955377A (en) | 1991-02-11 | 1999-09-21 | Biostar, Inc. | Methods and kits for the amplification of thin film based assays |
| AU1772992A (en) | 1991-04-10 | 1992-11-17 | Biosite Diagnostics Incorporated | Crosstalk inhibitors and their uses |
| JP3290988B2 (ja) | 1991-04-11 | 2002-06-10 | バイオサイト・ダイアグノスティックス・インコーポレイテッド | 多重リガンドを同時検出する新規接合体及び検定法 |
| US6143576A (en) | 1992-05-21 | 2000-11-07 | Biosite Diagnostics, Inc. | Non-porous diagnostic devices for the controlled movement of reagents |
| US5885527A (en) | 1992-05-21 | 1999-03-23 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membrances |
| US5494829A (en) | 1992-07-31 | 1996-02-27 | Biostar, Inc. | Devices and methods for detection of an analyte based upon light interference |
| US5824799A (en) | 1993-09-24 | 1998-10-20 | Biosite Diagnostics Incorporated | Hybrid phthalocyanine derivatives and their uses |
| US6811773B1 (en) | 1993-12-22 | 2004-11-02 | Human Genome Sciences, Inc. | Human monocyte colony inhibitory factor (M-CIF) polypeptides |
| US6113855A (en) | 1996-11-15 | 2000-09-05 | Biosite Diagnostics, Inc. | Devices comprising multiple capillarity inducing surfaces |
| US5947124A (en) | 1997-03-11 | 1999-09-07 | Biosite Diagnostics Incorporated | Diagnostic for determining the time of a heart attack |
| US6057098A (en) | 1997-04-04 | 2000-05-02 | Biosite Diagnostics, Inc. | Polyvalent display libraries |
| AU2003223172A1 (en) | 2002-02-12 | 2003-09-04 | Quark Biotech, Inc. | Use of the axl receptor for diagnosis and treatment of renal disease |
| US20120064089A1 (en) * | 2002-11-15 | 2012-03-15 | Morehouse School Of Medicine | Anti-cxcl16 and anti-cxcr6 antibodies for the prevention and treatment of cancer and cancer cell migration |
| EP1915614A4 (en) | 2005-07-21 | 2009-03-25 | Univ Johns Hopkins | METHOD FOR DETECTING AND TREATING AN ACUTE KIDNEY INJURY |
| WO2007035843A2 (en) * | 2005-09-21 | 2007-03-29 | Dask Technologies, Llc | Methods and compositions for organ and tissue functionality |
| US20110059537A1 (en) | 2007-09-20 | 2011-03-10 | Caritas St. Elizabeth's Medical Center Of Boston, Inc. | Method for estimating risk of acute kidney injury |
| WO2009114110A1 (en) | 2008-03-08 | 2009-09-17 | Immungene, Inc. | Engineered fusion molecules immunotherapy in cancer and inflammatory diseases |
| CA2740923A1 (en) * | 2008-10-21 | 2010-04-29 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP2462437A4 (en) * | 2009-08-07 | 2013-01-30 | Rules Based Medicine Inc | METHOD AND DEVICES FOR DETECTING DIABETIC NEPHROPATHY AND ASSOCIATED DISEASES THEREOF |
| CA2774223A1 (en) | 2009-09-21 | 2011-03-24 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| AU2010315008B2 (en) | 2009-11-07 | 2015-12-03 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| NZ600160A (en) * | 2009-11-07 | 2014-05-30 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US20120156701A1 (en) * | 2009-12-20 | 2012-06-21 | Joseph Anderberg | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2011075744A1 (en) | 2009-12-20 | 2011-06-23 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| AU2011213684B2 (en) * | 2010-02-05 | 2014-11-20 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| NZ605698A (en) | 2010-06-23 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| IN2012MN02812A (https=) * | 2010-06-23 | 2015-05-22 | Astute Medical Inc | |
| NZ606124A (en) * | 2010-06-23 | 2015-05-29 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| UY33492A (es) * | 2010-07-09 | 2012-01-31 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| WO2012136548A1 (en) | 2011-04-04 | 2012-10-11 | Universiteit Gent | Biomarkers for acute kidney injury |
| PT2748605T (pt) | 2011-08-26 | 2019-05-03 | Astute Medical Inc | Processos e composições para o diagnóstico e o prognóstico de lesões renais e de insuficiência renal |
| US10935548B2 (en) * | 2011-12-08 | 2021-03-02 | Astute Medical, Inc. | Methods for diagnosis and prognosis of renal injury and renal failure using insulin-like growth factor-binding protein 7 and metalloproteinase inhibitor 2 |
| WO2013096740A1 (en) * | 2011-12-21 | 2013-06-27 | Alere San Diego Inc. | Methods and compositions for assigning likelihood of chronic kidney disease progression |
| EP2962109A4 (en) | 2013-02-26 | 2016-12-07 | Astute Medical Inc | METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE |
| CA2965153C (en) | 2014-10-20 | 2023-10-24 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
-
2015
- 2015-10-20 CA CA2965153A patent/CA2965153C/en active Active
- 2015-10-20 EP EP15853584.9A patent/EP3210018B1/en active Active
- 2015-10-20 PT PT15853584T patent/PT3210018T/pt unknown
- 2015-10-20 KR KR1020177013539A patent/KR102431003B1/ko active Active
- 2015-10-20 AU AU2015336069A patent/AU2015336069B2/en active Active
- 2015-10-20 US US15/520,817 patent/US11333671B2/en active Active
- 2015-10-20 EP EP21186630.6A patent/EP3968022A1/en active Pending
- 2015-10-20 ES ES15853584T patent/ES2907551T3/es active Active
- 2015-10-20 MX MX2017005126A patent/MX388231B/es unknown
- 2015-10-20 BR BR112017008218A patent/BR112017008218A2/pt not_active Application Discontinuation
- 2015-10-20 WO PCT/US2015/056462 patent/WO2016064877A2/en not_active Ceased
- 2015-10-20 CN CN201910986041.5A patent/CN110702921B/zh active Active
- 2015-10-20 JP JP2017521231A patent/JP6792553B2/ja active Active
- 2015-10-20 EA EA201790696A patent/EA201790696A1/ru unknown
- 2015-10-20 CN CN201580068922.9A patent/CN107003301B/zh active Active
-
2020
- 2020-11-06 JP JP2020185705A patent/JP7002623B2/ja active Active
-
2021
- 2021-12-27 JP JP2021211779A patent/JP7217796B2/ja active Active
-
2022
- 2022-02-21 AU AU2022201130A patent/AU2022201130B2/en active Active
- 2022-03-31 US US17/710,832 patent/US12099067B2/en active Active
-
2023
- 2023-01-24 JP JP2023008480A patent/JP2023052587A/ja active Pending
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