EA201790574A1 - Композиция, содержащая гликозаминогликаны и белки - Google Patents

Композиция, содержащая гликозаминогликаны и белки

Info

Publication number
EA201790574A1
EA201790574A1 EA201790574A EA201790574A EA201790574A1 EA 201790574 A1 EA201790574 A1 EA 201790574A1 EA 201790574 A EA201790574 A EA 201790574A EA 201790574 A EA201790574 A EA 201790574A EA 201790574 A1 EA201790574 A1 EA 201790574A1
Authority
EA
Eurasian Patent Office
Prior art keywords
proteins
modified
hydrolyzed
glycosaminoglycans
chemically
Prior art date
Application number
EA201790574A
Other languages
English (en)
Other versions
EA035414B1 (ru
Inventor
Тьерри Швитцгюэбель
Original Assignee
Шондронест Са
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Шондронест Са filed Critical Шондронест Са
Publication of EA201790574A1 publication Critical patent/EA201790574A1/ru
Publication of EA035414B1 publication Critical patent/EA035414B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/02—Dextran; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/04—Alginic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/10—Heparin; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/30—Materials or treatment for tissue regeneration for muscle reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/32—Materials or treatment for tissue regeneration for nerve reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)

Abstract

Композиция, включающая полигидроксиуретаны, гликозаминогликаны, гидролизованные гликозаминогликаны, гликозамины гликозаминогликанов, модифицированные или не модифицированные химически, и белок или пептид, где белок представляет собой коллаген, эластин, кератин, фибронектин, актин, миозин, ламинин, пептид или смесь перечисленных белков или пептидов, фибриллированных, гидролизованных, модифицированных химически или нефибриллированных, негидролизованных, немодифицированных химически. Такую гомогенную композицию получают реакцией полимеризации или образования ковалентных связей между двумя препаратами, содержащими циклические поликарбонаты, полиамины, гликозаминогликаны, гидролизованные гликозаминогликаны, гликозамины, модифицированные или не модифицированные химически, и белки или пептиды или смеси таких белков или пептидов, фибриллированных, гидролизованных, модифицированных или нефибриллированных, негидролизованных, не модифицированных химически.
EA201790574A 2014-09-18 2015-09-04 Комбинация, содержащая гликозаминогликаны и белки EA035414B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IB2014064631 2014-09-18
IB2015054225 2015-06-04
PCT/IB2015/056740 WO2016042434A1 (en) 2014-09-18 2015-09-04 Composition containing glycosaminoglycans and proteins

Publications (2)

Publication Number Publication Date
EA201790574A1 true EA201790574A1 (ru) 2017-09-29
EA035414B1 EA035414B1 (ru) 2020-06-10

Family

ID=54292838

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201790574A EA035414B1 (ru) 2014-09-18 2015-09-04 Комбинация, содержащая гликозаминогликаны и белки

Country Status (18)

Country Link
US (1) US10478523B2 (ru)
EP (1) EP3193952B1 (ru)
JP (1) JP6648142B2 (ru)
KR (1) KR20170075723A (ru)
CN (1) CN106714856B (ru)
AU (1) AU2015316497B2 (ru)
BR (1) BR112017005338B1 (ru)
CA (1) CA2960832A1 (ru)
DK (1) DK3193952T3 (ru)
EA (1) EA035414B1 (ru)
ES (1) ES2729301T3 (ru)
HR (1) HRP20190884T1 (ru)
HU (1) HUE044268T2 (ru)
IL (1) IL251236B (ru)
PL (1) PL3193952T3 (ru)
SG (1) SG11201702160TA (ru)
WO (1) WO2016042434A1 (ru)
ZA (1) ZA201701816B (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024003942A (ja) * 2022-06-28 2024-01-16 朝日インテック株式会社 長尺状医療機器および長尺状医療機器の製造方法
CN115850121B (zh) * 2022-11-17 2024-07-19 中国科学院天津工业生物技术研究所 一种基于赤藓糖醇的聚氨酯预聚物及其合成和应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3072613A (en) 1957-08-20 1963-01-08 Union Carbide Corp Multiple cyclic carbonate polymers
US5475052A (en) * 1988-11-21 1995-12-12 Collagen Corporation Collagen-synthetic polymer matrices prepared using a multiple step reaction
US5510418A (en) * 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US6562781B1 (en) * 1995-11-30 2003-05-13 Hamilton Civic Hospitals Research Development Inc. Glycosaminoglycan-antithrombin III/heparin cofactor II conjugates
ITPD980037A1 (it) * 1998-02-25 1999-08-25 Fidia Advanced Biopolymers Srl Acido ialuronico solfatato e i suoi derivati legati covalentemente a polimeri sintetici pe la preparazione di biomateriali e per il rivesti
PL365671A1 (en) * 2000-09-08 2005-01-10 Gryphon Therapeutics, Inc. Synthetic erythropoiesis stimulating proteins
US7226611B2 (en) * 2001-04-02 2007-06-05 Yaizu Suisankagaku Industry Co., Ltd. Glycosaminoglycan/collagen complexes and use thereof
MXPA05009429A (es) * 2003-03-05 2005-12-12 Halozyme Inc Glicoproteina hialuronidasa soluble (shasegp), proceso para preparar la misma, usos y composiciones farmaceuticas que la comprenden.
EP1541568A1 (de) * 2003-12-09 2005-06-15 Deutsches Wollforschungsinstitut an der Rheinisch-Westfälischen Technischen Hochschule Aachen e.V. Reaktive cyclische Carbonate und Harnstoffe zur Modifizierung von Biomolekülen, Polymeren und Oberflächen
US20070184087A1 (en) * 2006-02-06 2007-08-09 Bioform Medical, Inc. Polysaccharide compositions for use in tissue augmentation
WO2008141326A1 (en) * 2007-05-14 2008-11-20 Tyco Healthcare Group Lp Biodegradable peptide releasing polymers
US20090068250A1 (en) * 2007-09-07 2009-03-12 Philippe Gravagna Bioresorbable and biocompatible compounds for surgical use
JP5277233B2 (ja) * 2010-11-19 2013-08-28 大日精化工業株式会社 熱可塑性ポリヒドロキシウレタンの製造方法
US20130116411A1 (en) * 2011-09-06 2013-05-09 Allergan, Inc. Methods of making hyaluronic acid/collagen compositions

Also Published As

Publication number Publication date
CN106714856A (zh) 2017-05-24
IL251236B (en) 2019-09-26
HUE044268T2 (hu) 2019-10-28
JP6648142B2 (ja) 2020-02-14
SG11201702160TA (en) 2017-04-27
IL251236A0 (en) 2017-05-29
ES2729301T3 (es) 2019-10-31
BR112017005338A2 (pt) 2017-12-19
CN106714856B (zh) 2020-03-03
CA2960832A1 (en) 2016-03-24
HRP20190884T1 (hr) 2019-09-20
DK3193952T3 (da) 2019-06-11
ZA201701816B (en) 2018-05-30
EP3193952B1 (en) 2019-05-08
AU2015316497B2 (en) 2019-08-22
JP2017528296A (ja) 2017-09-28
EP3193952A1 (en) 2017-07-26
KR20170075723A (ko) 2017-07-03
US20170296698A1 (en) 2017-10-19
WO2016042434A1 (en) 2016-03-24
PL3193952T3 (pl) 2019-09-30
BR112017005338B1 (pt) 2021-04-06
AU2015316497A1 (en) 2017-04-06
US10478523B2 (en) 2019-11-19
EA035414B1 (ru) 2020-06-10

Similar Documents

Publication Publication Date Title
CY1121632T1 (el) Η rv2386c πρωτεϊνη φυματιωσης, συνθεσεις και χρησεις αυτης
CY1120729T1 (el) Πεπτιδια και συνθεσεις για τη θεραπεια τραυματισμου των αρθρωσεων
EA202190906A1 (ru) Рекомбинантное получение препаратов пептидов коллагена и их применение
EA201691111A1 (ru) Химерные белки фактора viii и их применение
CL2018000226A1 (es) Mezcla de péptidos (divisional solicitud 201601405)
BR112017008165A2 (pt) anticorpos de domínio único direcionados contra antígenos intracelulares
EA201491049A1 (ru) Противораковый слитый белок
EA201390820A1 (ru) Слитый белок против рака
EA201691589A1 (ru) Стабилизированные основанные на фибронектине каркасные молекулы
PE20170665A1 (es) Anticuerpos anti-tau humanizados
MX2016008539A (es) Variantes de region fc con propiedades de union a receptor fc neonatal (fcrn) modificadas y de union a proteina a mantenidas.
EA201491277A1 (ru) Противораковый слитый белок
EA201171494A1 (ru) Миметики белка smac
EA201792245A1 (ru) Биоконъюгаты и их применения
ES2722773T3 (es) Polipéptidos de fHbp meningocócicos modificados
ES2721309T3 (es) Composición para preparar tagatosa y método para preparar tagatosa a partir de fructosa
EA201391005A1 (ru) Слитый белок против злокачественной опухоли
EP4397374A3 (en) Improved peptide pharmaceuticals for insulin resistance
EA202091350A1 (ru) Связывающие молекулы, специфично связывающиеся с тау-белком
CL2017000200A1 (es) Célula huésped mejorada para producir proteinas
EA201992281A1 (ru) Связывающие молекулы, специфично связывающиеся с тау-белком
EA201892325A1 (ru) Композиции и способы детектирования белков клетки-хозяина
MX2016000393A (es) Modificaciones de proteinas quimioenzimaticas de lisina utilizando transglutaminasa microbiana.
EA201590601A1 (ru) Применение pedf-производных полипептидов для лечения остеоартрита
UA117493C2 (uk) Гібридна конструкція, що включає антигенсполучний фрагмент, специфічний до сироваткового альбуміну, й ефекторний компонент, та способи її одержання

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU