EA201590585A1 - Продукт, включающий никотинсодержащее вещество и противоопухолевое средство - Google Patents

Продукт, включающий никотинсодержащее вещество и противоопухолевое средство

Info

Publication number
EA201590585A1
EA201590585A1 EA201590585A EA201590585A EA201590585A1 EA 201590585 A1 EA201590585 A1 EA 201590585A1 EA 201590585 A EA201590585 A EA 201590585A EA 201590585 A EA201590585 A EA 201590585A EA 201590585 A1 EA201590585 A1 EA 201590585A1
Authority
EA
Eurasian Patent Office
Prior art keywords
containing substance
composition
nicotine
risk
product including
Prior art date
Application number
EA201590585A
Other languages
English (en)
Russian (ru)
Inventor
Бейзил Ригас
Джейсон Ригас
Original Assignee
Бейзил Ригас
Джейсон Ригас
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бейзил Ригас, Джейсон Ригас filed Critical Бейзил Ригас
Publication of EA201590585A1 publication Critical patent/EA201590585A1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00Chewing gum
    • A23G4/06Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/068Chewing gum characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00Chewing gum
    • A23G4/06Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/12Chewing gum characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10Chemical features of tobacco products or tobacco substitutes
    • A24B15/16Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465Nicotine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A61K31/6615Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058Chewing gums
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/008Electronic counters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0083Timers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/06Inhaling appliances shaped like cigars, cigarettes or pipes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24FSMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F13/00Appliances for smoking cigars or cigarettes
    • A24F13/02Cigar or cigarette holders
    • A24F13/12Cigar or cigarette holders combined with other objects, e.g. writing utensils
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0085Inhalators using ultrasonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Physiology (AREA)
  • Addiction (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EA201590585A 2012-09-21 2013-09-23 Продукт, включающий никотинсодержащее вещество и противоопухолевое средство EA201590585A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261703999P 2012-09-21 2012-09-21
US14/013,019 US20140088045A1 (en) 2012-09-21 2013-08-28 Product comprising a nicotine-containing material and an anti-cancer agent
PCT/US2013/061206 WO2014047569A2 (en) 2012-09-21 2013-09-23 Product comprising a nicotine-containing material and an anti-cancer agent

Publications (1)

Publication Number Publication Date
EA201590585A1 true EA201590585A1 (ru) 2016-04-29

Family

ID=50339457

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201590585A EA201590585A1 (ru) 2012-09-21 2013-09-23 Продукт, включающий никотинсодержащее вещество и противоопухолевое средство

Country Status (9)

Country Link
US (2) US20140088045A1 (enExample)
EP (1) EP2916847A4 (enExample)
JP (1) JP2015531793A (enExample)
KR (1) KR20150084794A (enExample)
CN (1) CN104918621A (enExample)
CA (1) CA2885739A1 (enExample)
EA (1) EA201590585A1 (enExample)
IN (1) IN2015DN02782A (enExample)
WO (1) WO2014047569A2 (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011133867A2 (en) * 2010-04-23 2011-10-27 The Regents Of The University Of Colorado, A Body Corporate Vaccines, methods of administering vaccines, methods and products for treating and/or delaying onset of dysplastic lesions, and wafers for oral administration
CA2822738C (en) 2010-12-22 2021-06-08 Exonoid Medical Devices Ltd. Method and system for drug delivery
FR3015186A1 (fr) * 2014-03-11 2015-06-26 Antoine Piccirilli Utilisation d'une composition renfermant du 1,3-propanediol comme e-liquide
WO2015148649A2 (en) * 2014-03-26 2015-10-01 Basil Rigas Systems and methods for ameliorating the effects of tobacco products
EP3129024A4 (en) * 2014-04-08 2017-11-22 Sansa Corporation (Barbados) Inc. Nicotine formulations and methods of making the same
KR102428028B1 (ko) 2014-04-28 2022-08-03 필립모리스 프로덕츠 에스.에이. 향미를 가진 니코틴 분말 흡입기
MX381937B (es) 2014-04-28 2025-03-13 Philip Morris Products Sa Inhalador de polvo de nicotina.
BR112016022476B1 (pt) 2014-04-28 2021-10-13 Philip Morris Products S.A. Inalador de pó de nicotina e método de inalação de nicotina para os pulmões de um usuário
US9896429B2 (en) 2014-05-27 2018-02-20 R.J. Reynolds Tobacco Company Nicotine salts, co-crystals, and salt co-crystal complexes
EP3871515B1 (en) 2014-05-27 2025-04-16 R. J. Reynolds Tobacco Company Nicotine salts, co-crystals, and salt co-crystal complexes
US10508096B2 (en) 2014-05-27 2019-12-17 R.J. Reynolds Tobacco Company Nicotine salts, co-crystals, and salt co-crystal complexes
GB2527597B (en) * 2014-06-27 2016-11-23 Relco Induction Dev Ltd Electronic Vapour Inhalers
US11298477B2 (en) 2014-06-30 2022-04-12 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
EP3160565B1 (en) 2014-06-30 2021-08-18 Syqe Medical Ltd. Devices and systems for pulmonary delivery of active agents
IL294075A (en) 2014-06-30 2022-08-01 Syqe Medical Ltd Flow regulating inhaler
BR112016030829B1 (pt) 2014-06-30 2022-02-22 Syqe Medical Ltd Cartucho de dosagem para dispositivo inalador
WO2016001922A1 (en) * 2014-06-30 2016-01-07 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
MX2017000057A (es) 2014-06-30 2017-06-30 Syqe Medical Ltd Procedimiento y dispositivo para vaporizacion e inhalacion de sustancias aisladas.
CN113115993A (zh) 2014-10-29 2021-07-16 奥驰亚客户服务有限责任公司 用于电子烟装置的无乙醇凝胶配方筒体
WO2016069903A1 (en) 2014-10-29 2016-05-06 Altria Client Services Llc E-vaping cartridge
CN104544542B (zh) * 2014-12-24 2017-04-26 广西中烟工业有限责任公司 一种真空冷冻干燥薄荷粒电子烟油的制备方法
GB2534210B (en) * 2015-01-19 2017-07-19 Ngip Res Ltd Aerosol-generating article
BR112017022201A2 (pt) 2015-04-15 2018-07-03 Sansa Corporation (Barbados) Inc. dispositivo para adicionar um componente de aroma ou supressor de tosse a um inalador, inalador de pó seco, e, método para inalação de pó seco
US10149844B2 (en) 2015-09-16 2018-12-11 Philip Morris Products S.A. Inhalable nicotine formulations, and methods of making and using thereof
US9585835B1 (en) * 2015-09-16 2017-03-07 Sansa Corporation (Barbados) Inc. Inhalable nicotine formulations and methods of making and using the same
CN108495563B (zh) * 2015-11-25 2022-04-26 R.J.雷诺兹烟草公司 烟碱盐、共晶体和盐共晶体配合物
CA3008211A1 (en) 2015-12-24 2017-06-29 Philip Morris Products S.A. Nicotine powder delivery system
CN117695207A (zh) 2015-12-24 2024-03-15 菲利普莫里斯生产公司 带香味尼古丁粉末
WO2017109678A1 (en) 2015-12-24 2017-06-29 Philip Morris Products S.A. Nicotine particle capsule
CA3009599A1 (en) 2016-01-06 2017-07-13 Syqe Medical Ltd. Low dose therapeutic treatment
US9867397B2 (en) 2016-01-11 2018-01-16 Patrick Beymer Nicotine delivery system
GB201602831D0 (en) 2016-02-18 2016-04-06 British American Tobacco Co Flavour delivery device
PL3481471T3 (pl) 2016-07-07 2021-01-11 Philip Morris Products S.A. Układ inhalatora nikotyny
US20180036496A1 (en) * 2016-08-02 2018-02-08 James Riviello Medication Delivery System
US20220087305A1 (en) * 2018-12-28 2022-03-24 Philip Morris Products S.A. High viscosity nicotine formulation
US20220071268A1 (en) * 2018-12-28 2022-03-10 Philip Morris Products S.A. Nicotine formulation comprising metal salt
JP7551621B2 (ja) * 2018-12-28 2024-09-17 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 低モル質量金属塩を含む液体ニコチン製剤
EP3973794A4 (en) * 2019-05-21 2022-12-21 Japan Tobacco Inc. PERFUMED FILM FOR HEATED AROMA INHALER AND HEATED AROMA INHALER
WO2021126313A1 (en) * 2019-07-15 2021-06-24 The Research Foundation For The State University Of New York Nicotine materials, methods of making same, and uses thereof
LU101519B1 (en) * 2019-12-02 2021-06-07 Herrera Arturo Solis (S)-3-[1-MethyIpyrrolidin-2-yl]pyridine, analogues thereof, precursors thereof, or its derivatives, for the use as a pharmaceutical in form of a solid substance and a tablet
WO2022102543A1 (ja) * 2020-11-13 2022-05-19 日本たばこ産業株式会社 センブラトリエンジオールを含むたばこ抽出物およびその製造方法
KR20230158005A (ko) 2021-03-18 2023-11-17 씨젠 인크. 생물학적 활성 화합물의 내재화된 접합체로부터의 선택적 약물 방출
WO2024090890A1 (ko) * 2022-10-27 2024-05-02 주식회사 케이티앤지 흡입용 저용량 니코틴 건조 분말 조성물
WO2024194922A1 (ja) * 2023-03-17 2024-09-26 日本たばこ産業株式会社 香味組成物及び香味吸引器

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050236006A1 (en) * 2004-04-24 2005-10-27 Anderson Cowan Smoking cessation devices, methods of use and methods of conducting business therewith
JP5707131B2 (ja) * 2007-08-10 2015-04-22 リーガス,バジル 抗炎症性化合物とその用途
US20100124560A1 (en) * 2008-11-14 2010-05-20 Mcneil Ab Multi portion intra-oral dosage form and use thereof
WO2011133215A1 (en) * 2010-04-19 2011-10-27 Health Research Inc. Method of identifying and treating a person having a predisposition to or afflicted with parkinson disease
WO2011133475A2 (en) * 2010-04-19 2011-10-27 Sri International Compositions and method for the treatment of multiple myeloma

Also Published As

Publication number Publication date
IN2015DN02782A (enExample) 2015-09-04
KR20150084794A (ko) 2015-07-22
CN104918621A (zh) 2015-09-16
US20140088045A1 (en) 2014-03-27
WO2014047569A2 (en) 2014-03-27
US20140088044A1 (en) 2014-03-27
EP2916847A2 (en) 2015-09-16
WO2014047569A3 (en) 2014-07-17
CA2885739A1 (en) 2014-03-27
EP2916847A4 (en) 2016-06-08
JP2015531793A (ja) 2015-11-05
WO2014047569A9 (en) 2014-05-30

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