EA201492208A1 - Композиция в водной среде, включающая по меньшей мере одну гиалуроновую кислоту и по меньшей мере одну водорастворимую соль октасульфата сахарозы - Google Patents
Композиция в водной среде, включающая по меньшей мере одну гиалуроновую кислоту и по меньшей мере одну водорастворимую соль октасульфата сахарозыInfo
- Publication number
- EA201492208A1 EA201492208A1 EA201492208A EA201492208A EA201492208A1 EA 201492208 A1 EA201492208 A1 EA 201492208A1 EA 201492208 A EA201492208 A EA 201492208A EA 201492208 A EA201492208 A EA 201492208A EA 201492208 A1 EA201492208 A1 EA 201492208A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- less
- composition
- hyaluronic acid
- salt
- vodorable
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 8
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title abstract 2
- 229920002674 hyaluronan Polymers 0.000 title abstract 2
- 229960003160 hyaluronic acid Drugs 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- WEPNHBQBLCNOBB-FZJVNAOYSA-N sucrose octasulfate Chemical class OS(=O)(=O)O[C@@H]1[C@H](OS(O)(=O)=O)[C@H](COS(=O)(=O)O)O[C@]1(COS(O)(=O)=O)O[C@@H]1[C@H](OS(O)(=O)=O)[C@@H](OS(O)(=O)=O)[C@@H](OS(O)(=O)=O)[C@@H](COS(O)(=O)=O)O1 WEPNHBQBLCNOBB-FZJVNAOYSA-N 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 230000037303 wrinkles Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/91—Injection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Birds (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Immunology (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261659140P | 2012-06-13 | 2012-06-13 | |
| FR1255543A FR2991876B1 (fr) | 2012-06-13 | 2012-06-13 | Composition, en milieu aqueux, comprenant au moins un acide hyaluronique et au moins un sel hydrosoluble de sucrose octasulfate |
| PCT/FR2013/051380 WO2013186493A2 (fr) | 2012-06-13 | 2013-06-13 | Composition, en milieux aqueux, comprenant au moins un acide hyaluronique et au moins un sel hydrosoluble de sucrose octasulfate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201492208A1 true EA201492208A1 (ru) | 2015-04-30 |
Family
ID=46785648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201492208A EA201492208A1 (ru) | 2012-06-13 | 2013-06-13 | Композиция в водной среде, включающая по меньшей мере одну гиалуроновую кислоту и по меньшей мере одну водорастворимую соль октасульфата сахарозы |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9314530B2 (enExample) |
| EP (1) | EP2861301B1 (enExample) |
| JP (1) | JP6178414B2 (enExample) |
| KR (1) | KR20150023468A (enExample) |
| CN (1) | CN104394934B (enExample) |
| AU (1) | AU2013276343B2 (enExample) |
| BR (1) | BR112014029510A2 (enExample) |
| CA (1) | CA2876057A1 (enExample) |
| EA (1) | EA201492208A1 (enExample) |
| ES (1) | ES2728686T3 (enExample) |
| FR (1) | FR2991876B1 (enExample) |
| IL (1) | IL235776A0 (enExample) |
| MX (1) | MX354544B (enExample) |
| PL (1) | PL2861301T3 (enExample) |
| SG (1) | SG11201407857SA (enExample) |
| TR (1) | TR201907427T4 (enExample) |
| WO (1) | WO2013186493A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3613423T (pt) | 2013-07-10 | 2022-12-07 | Matrix Biology Inst | Composições de hialuronano de elevada elasticidade e suas utilizações |
| US9421198B2 (en) | 2013-07-30 | 2016-08-23 | Teoxane | Composition comprising hyaluronic acid and mepivacaine |
| FR3015290B1 (fr) * | 2013-12-23 | 2017-01-13 | Lab Vivacy | Compositions d'acide hyaluronique compreant de la mepivacaine |
| CN106659663A (zh) * | 2014-06-30 | 2017-05-10 | 纽璀克斯技术公司 | 控制影响角化细胞和/或成纤维细胞和真皮的皮肤失调和皮肤老化的组合产品和美容组合物 |
| FR3032617B1 (fr) * | 2015-02-16 | 2018-03-16 | Kylane Laboratoires Sa | Procede de preparation d un hydrogel injectable; hydrogel obtenu; utilisation de l hydrogel obtenu |
| US10004824B2 (en) | 2015-05-11 | 2018-06-26 | Laboratoires Vivacy | Compositions comprising at least one polyol and at least one anesthetic |
| FR3036035B1 (fr) | 2015-05-11 | 2018-10-05 | Laboratoires Vivacy | Compositions comprenant au moins un polyol et au moins un anesthesique |
| CN104926889A (zh) * | 2015-05-24 | 2015-09-23 | 广西师范学院 | 蔗糖硫酸酯铜银类化合物及其制作方法和用途 |
| PT3352766T (pt) * | 2015-09-24 | 2022-03-22 | Matrix Biology Inst | Composições de hialuronano de elevada elasticidade e processos para o seu uso |
| FR3044557B1 (fr) * | 2015-12-07 | 2017-12-01 | Benedicte Vincente Gavard Molliard Tauzin | Nouvelle composition injectable; procede de preparation de ladite composition; utilisation de ladite composition |
| WO2017102001A1 (fr) | 2015-12-16 | 2017-06-22 | Vplus International Sa | Composition d'acide hyaluronique pour injections peniennes |
| FR3047666A1 (fr) * | 2016-02-15 | 2017-08-18 | Benedicte Vincente Gavard Molliard Tauzin | Composition injectable; procede de preparation de ladite composition; utilisation de ladite composition |
| FR3058064B1 (fr) | 2016-10-28 | 2020-08-07 | Lab Vivacy | Composition a base d'acide hyaluronique comprenant de la mepivacaine |
| US20200093852A1 (en) * | 2016-12-13 | 2020-03-26 | Keats NELMS | Methods of Treating Ocular Disorders |
| US11787783B2 (en) | 2016-12-13 | 2023-10-17 | Beta Therapeutics Pty Ltd | Heparanase inhibitors and use thereof |
| MX2019006863A (es) | 2016-12-13 | 2019-09-13 | Beta Therapeutics Pty Ltd | Inhibidores de heparanasa y uso de los mismos. |
| FR3109153B1 (fr) | 2020-04-10 | 2022-07-15 | Teoxane SA | Compositions à base d’au moins deux glycosaminoglycanes |
| KR102664134B1 (ko) * | 2023-11-23 | 2024-05-10 | 한국콜마주식회사 | 히알루론산 및 이의 유도체를 포함하는 화장료 조성물 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2715091A (en) | 1949-11-28 | 1955-08-09 | Nat Res Dev | Dextran sulfate as anticoagulant, process of preparing same, and sterile solution thereof |
| AU607690B2 (en) | 1985-12-24 | 1991-03-14 | Marion Laboratories, Inc. | Use of synthetic sulfated saccharides to enhance wound healing |
| DK505488D0 (da) * | 1987-12-21 | 1988-09-09 | Bar Shalom Daniel | Middel og anvendelse af samme |
| US5916880A (en) | 1987-12-21 | 1999-06-29 | Bukh Meditec A/S | Reduction of skin wrinkling using sulphated sugars |
| DK86492D0 (da) | 1992-06-30 | 1992-06-30 | Bukh Meditec | Laegemiddel |
| AU4941297A (en) | 1996-11-15 | 1998-06-10 | Dumex-Alpharma A/S | A method for promoting tissue repair |
| JP2000178196A (ja) * | 1998-12-11 | 2000-06-27 | Seikagaku Kogyo Co Ltd | 新規ヒアルロニダーゼ阻害剤及び外用剤 |
| GB9902412D0 (en) | 1999-02-03 | 1999-03-24 | Fermentech Med Ltd | Process |
| EP1423081A4 (en) * | 2001-06-25 | 2005-05-25 | Depuy Int Ltd | COMPOSITION WITH GLYCOSAMINOGYCANES AND HYALURONIDASE INHIBITORS FOR THE TREATMENT OF ARTHRITIC JOINTS |
| US20050187150A1 (en) * | 2001-10-31 | 2005-08-25 | New York University | Structure-based design and synthesis of FGF inhibitors and FGF modulator compounds |
| MXPA01011542A (es) | 2001-11-13 | 2003-05-22 | Alcon Inc | Regeneracion del cartilago articular da°ado por la osteoartritis de grado i y ii, mediante la aplicacion intra-articular de una mezcla de hialuronato de sodio y de condroitin sulfato en un vehiculo de gel. |
| AUPS052802A0 (en) | 2002-02-15 | 2002-03-07 | Praxis Pharmaceuticals International Pty Ltd | Carbohydrate-based anti-wrinkle and tissue remodelling compounds |
| US20080003258A1 (en) | 2002-10-16 | 2008-01-03 | Marcum Frank D | Composition and Method for Treating Rheumatoid Arthritis |
| PT1560588E (pt) | 2002-10-16 | 2012-01-06 | Arthrodynamic Technologies Animal Health Division Inc | Tratamento para sinovite traumática e lesões na cartilagem |
| FR2861734B1 (fr) | 2003-04-10 | 2006-04-14 | Corneal Ind | Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus |
| GB0329907D0 (en) | 2003-12-23 | 2004-01-28 | Innomed Ltd | Compositions |
| FR2865737B1 (fr) | 2004-02-03 | 2006-03-31 | Anteis Sa | Gel reticule biocompatible |
| WO2006017752A2 (en) | 2004-08-05 | 2006-02-16 | Ivax Corporation | Sulfated oligosaccharides |
| AU2005272578A1 (en) * | 2004-08-13 | 2006-02-23 | Angiotech International Ag | Compositions and methods using hyaluronic acid and hyluronidase inhibitors |
| WO2008011836A2 (es) | 2006-07-25 | 2008-01-31 | Osmotica Corp. | Soluciones oftálmicas |
| JPWO2008020495A1 (ja) * | 2006-08-15 | 2010-01-07 | 東京化成工業株式会社 | 新規阻害剤 |
| FR2918276B1 (fr) | 2007-07-02 | 2010-01-22 | Anteis Sa | "utilisation d'un gel de polysaccharide(s)naturel(s)pour la preparation d'une formulation injectable de traitement des degenerescences articulaires" |
| ITMI20072237A1 (it) | 2007-11-27 | 2009-05-28 | Sigea Srl | Esteri misti butirrico-formico di polisaccaridi acidi, loro preparazione ed uso come dermocosmetici |
| US8394784B2 (en) * | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having multi-stage bioactive agent delivery |
| FR2924615B1 (fr) | 2007-12-07 | 2010-01-22 | Vivacy Lab | Hydrogel cohesif biodegradable. |
| FR2953522B1 (fr) | 2009-12-07 | 2012-03-09 | Fabre Pierre Dermo Cosmetique | Sucrose octasulfates de zinc, leur preparation et leurs applications pharmaceutiques et cosmetiques |
| US20110171310A1 (en) | 2010-01-13 | 2011-07-14 | Allergan Industrie, Sas | Hydrogel compositions comprising vasoconstricting and anti-hemorrhagic agents for dermatological use |
| FR2956322A1 (fr) | 2010-02-17 | 2011-08-19 | Urgo Lab | Utilisation d'oligosaccharides polysulfates synthetiques comme agents de detersion d'une plaie. |
| CA2805008C (en) * | 2010-07-12 | 2015-05-12 | Shin Poong Pharmaceutical Co., Ltd. | Filler composition for tissue augmentation comprising a hydrogel of hyaluronic acid cross-linked with alkylene diamine |
| FR2983483B1 (fr) | 2011-12-02 | 2014-11-14 | Vivacy Lab | Procede de substitution et reticulation simultanees d'un polysaccharide via ses fonctions hydroxyles |
-
2012
- 2012-06-13 FR FR1255543A patent/FR2991876B1/fr not_active Expired - Fee Related
-
2013
- 2013-06-12 US US13/916,236 patent/US9314530B2/en active Active
- 2013-06-13 CA CA2876057A patent/CA2876057A1/fr not_active Abandoned
- 2013-06-13 TR TR2019/07427T patent/TR201907427T4/tr unknown
- 2013-06-13 AU AU2013276343A patent/AU2013276343B2/en active Active
- 2013-06-13 ES ES13733396T patent/ES2728686T3/es active Active
- 2013-06-13 MX MX2014013949A patent/MX354544B/es active IP Right Grant
- 2013-06-13 PL PL13733396T patent/PL2861301T3/pl unknown
- 2013-06-13 KR KR20147036186A patent/KR20150023468A/ko not_active Withdrawn
- 2013-06-13 SG SG11201407857SA patent/SG11201407857SA/en unknown
- 2013-06-13 BR BR112014029510A patent/BR112014029510A2/pt not_active IP Right Cessation
- 2013-06-13 JP JP2015516668A patent/JP6178414B2/ja active Active
- 2013-06-13 WO PCT/FR2013/051380 patent/WO2013186493A2/fr not_active Ceased
- 2013-06-13 CN CN201380031227.6A patent/CN104394934B/zh active Active
- 2013-06-13 EP EP13733396.9A patent/EP2861301B1/fr active Active
- 2013-06-13 EA EA201492208A patent/EA201492208A1/ru unknown
-
2014
- 2014-11-18 IL IL235776A patent/IL235776A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2991876B1 (fr) | 2014-11-21 |
| US9314530B2 (en) | 2016-04-19 |
| US20140005140A1 (en) | 2014-01-02 |
| WO2013186493A3 (fr) | 2014-05-08 |
| EP2861301B1 (fr) | 2019-02-20 |
| FR2991876A1 (fr) | 2013-12-20 |
| KR20150023468A (ko) | 2015-03-05 |
| ES2728686T3 (es) | 2019-10-28 |
| WO2013186493A2 (fr) | 2013-12-19 |
| BR112014029510A2 (pt) | 2017-06-27 |
| AU2013276343A1 (en) | 2014-12-04 |
| SG11201407857SA (en) | 2015-02-27 |
| MX354544B (es) | 2018-03-09 |
| PL2861301T3 (pl) | 2020-08-24 |
| IL235776A0 (en) | 2015-01-29 |
| EP2861301A2 (fr) | 2015-04-22 |
| AU2013276343B2 (en) | 2017-06-15 |
| TR201907427T4 (tr) | 2019-06-21 |
| JP2015525099A (ja) | 2015-09-03 |
| JP6178414B2 (ja) | 2017-08-09 |
| CN104394934B (zh) | 2018-01-09 |
| CN104394934A (zh) | 2015-03-04 |
| CA2876057A1 (fr) | 2013-12-19 |
| MX2014013949A (es) | 2015-05-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TR201907427T4 (tr) | Sulu ortamda, en az bi̇r hyalüroni̇k asi̇t ve suda çözünür en az bi̇r oktasülfat sükroz tuzu i̇çeren bi̇leşi̇m | |
| CY1120334T1 (el) | Υποκατεστημενης 3-αλλογονοαλυλαμινης αναστολεις ssao και χρησεις αυτων | |
| CY1119058T1 (el) | Ενωσεις ιμιδαζοπυρρολιδινονης | |
| EA201692301A1 (ru) | Производные бороновой кислоты и их терапевтическое применение | |
| EA201590343A1 (ru) | Алкилпиримидиновые производные для лечения вирусных инфекций и дальнейших заболеваний | |
| WO2015095811A3 (en) | Combination therapy with neoantigen vaccine | |
| CY1118813T1 (el) | Φαρμακευτικες συνθεσεις συν-κρυσταλλων τραμαδολης και κοξιμπων | |
| EA201992133A1 (ru) | Производные пиперидино-пиримидина для лечения вирусных инфекций | |
| EA201591166A1 (ru) | Ингибиторы аутотаксина | |
| EA201590667A1 (ru) | Ациламинопиримидиновые производные для лечения вирусных инфекций и других заболеваний | |
| NZ732777A (en) | Ionizable cationic lipid for rna delivery | |
| EA201491672A1 (ru) | Гетероциклильные соединения как ингибиторы mek | |
| MX2015008627A (es) | Derivados de acido boronico y usos terapeuticos de los mismos. | |
| UA109010C2 (en) | Morpholino pyrividines and their use in therapy | |
| AR090491A1 (es) | Tratamiento de la esclerosis multiple con una combinacion de laquinimod y fumarato de dimetilo | |
| EA202090662A2 (ru) | ПРОИЗВОДНЫЕ ПИРРОЛО[3,2-d]ПИРИМИДИНА ДЛЯ ЛЕЧЕНИЯ ВИРУСНЫХ ИНФЕКЦИЙ И ДРУГИХ ЗАБОЛЕВАНИЙ | |
| MX2021006021A (es) | Procedimiento de disminucion de la inmunogenicidad de proteinas y peptidos. | |
| EA201590491A1 (ru) | Иммуногенная композиция | |
| UY34775A (es) | Uso de laquinimod en alta dosis para el tratamiento de la esclerosis múltiple | |
| EA201790223A1 (ru) | Водный препарат, содержащий парацетамол и ибупрофен | |
| MX346596B (es) | Oligodesoxinucleotidos inmunoestimuladores. | |
| MX2015009938A (es) | Macromoleculas en forma de estrella tolerantes a las sales. | |
| CL2013000866A1 (es) | Sales cristalinas oxalato y fosfato del conjugado naloxolpolietilenglicol; metodo de preparacion; composicion farmaceutica que lo comprende; y su uso para el tratamiento del dolor. | |
| EA201590041A1 (ru) | Твердая форма холиновой соли вемурафениба | |
| PH12015502717A1 (en) | Anti-fibrogenic compounds, methods and uses thereof |