EA201491815A1 - Цельные интравагинальные кольца, содержащие прогестерон, и способы изготовления и применения таких колец - Google Patents
Цельные интравагинальные кольца, содержащие прогестерон, и способы изготовления и применения таких колецInfo
- Publication number
- EA201491815A1 EA201491815A1 EA201491815A EA201491815A EA201491815A1 EA 201491815 A1 EA201491815 A1 EA 201491815A1 EA 201491815 A EA201491815 A EA 201491815A EA 201491815 A EA201491815 A EA 201491815A EA 201491815 A1 EA201491815 A1 EA 201491815A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- rings
- methods
- progesterons
- manufacturing
- application
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
- A61F6/14—Contraceptive devices; Pessaries; Applicators therefor for use by females intra-uterine type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
- A61F6/08—Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/0001—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor characterised by the choice of material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/17—Component parts, details or accessories; Auxiliary operations
- B29C45/72—Heating or cooling
- B29C45/7207—Heating or cooling of the moulded articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2083/00—Use of polymers having silicon, with or without sulfur, nitrogen, oxygen, or carbon only, in the main chain, as moulding material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/0005—Condition, form or state of moulded material or of the material to be shaped containing compounding ingredients
- B29K2105/0035—Medical or pharmaceutical agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/753—Medical equipment; Accessories therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Reproductive Health (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Mechanical Engineering (AREA)
- Manufacturing & Machinery (AREA)
- Urology & Nephrology (AREA)
- Pregnancy & Childbirth (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Surgical Instruments (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
Изобретение относится к цельным интравагинальным кольцам, содержащим прогестерон, способам изготовления и применения таких колец. Интравагинальные кольца содержат прогестерон, полисилоксановый эластомер и фармацевтически приемлемый углеводород или глицериновые эфиры жирной кислоты.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2611508P | 2008-02-04 | 2008-02-04 | |
US13945408P | 2008-12-19 | 2008-12-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201491815A1 true EA201491815A1 (ru) | 2015-03-31 |
EA031017B1 EA031017B1 (ru) | 2018-11-30 |
Family
ID=40939073
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201070919A EA021615B1 (ru) | 2008-02-04 | 2009-02-03 | Цельное интравагинальное кольцо, содержащее прогестерон, и способ изготовления и применения такого кольца |
EA201491815A EA031017B1 (ru) | 2008-02-04 | 2009-02-03 | Способ поддержания или замещения фазы жёлтого тела |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201070919A EA021615B1 (ru) | 2008-02-04 | 2009-02-03 | Цельное интравагинальное кольцо, содержащее прогестерон, и способ изготовления и применения такого кольца |
Country Status (26)
Country | Link |
---|---|
US (5) | US8580293B2 (ru) |
EP (2) | EP2359807B1 (ru) |
JP (2) | JP5507467B2 (ru) |
KR (3) | KR20140048321A (ru) |
CN (2) | CN104146948B (ru) |
AR (1) | AR070561A1 (ru) |
AU (1) | AU2009210779B2 (ru) |
BR (1) | BRPI0905946B8 (ru) |
CA (2) | CA3016642A1 (ru) |
CL (1) | CL2009000242A1 (ru) |
DK (2) | DK2359807T3 (ru) |
EA (2) | EA021615B1 (ru) |
ES (2) | ES2648640T3 (ru) |
HR (1) | HRP20171319T1 (ru) |
HU (1) | HUE035634T2 (ru) |
IL (2) | IL207376A (ru) |
LT (1) | LT2249757T (ru) |
MX (1) | MX337634B (ru) |
NZ (3) | NZ596844A (ru) |
PL (2) | PL2249757T3 (ru) |
PT (2) | PT2249757T (ru) |
SG (2) | SG187529A1 (ru) |
SI (2) | SI2359807T1 (ru) |
TW (3) | TWI599359B (ru) |
WO (1) | WO2009099586A2 (ru) |
ZA (2) | ZA201307321B (ru) |
Families Citing this family (18)
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LT2249757T (lt) | 2008-02-04 | 2017-09-25 | Ferring B.V. | Vientisi intravaginaliniai žiedai, apimantys progesteroną, ir jų gamybos bei panaudojimo būdai |
KR20130045332A (ko) * | 2010-06-22 | 2013-05-03 | 지아시앙 차오 | 항콜린제를 포함하는 질내 기구 및 그 제조방법 |
US8580294B2 (en) | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
EP2641602A1 (en) * | 2012-03-23 | 2013-09-25 | PregLem S.A. | Method for treating gynecological diseases |
US9775905B2 (en) | 2013-02-08 | 2017-10-03 | Qpharma Ab | Intrauterine device and method for reducing the rate of diffusion of active ingredients in said device by adding inert particulates to a polymeric coating |
CN103405810A (zh) * | 2013-08-02 | 2013-11-27 | 苏州市马尔泰新材料有限公司 | 一种含有甲基丙烯酸甲酯树脂的阴道模具 |
CN103445892A (zh) * | 2013-08-02 | 2013-12-18 | 苏州市马尔泰新材料有限公司 | 一种含有甲酯树脂和雌酚的阴道模具 |
CN103394127A (zh) * | 2013-08-02 | 2013-11-20 | 苏州市马尔泰新材料有限公司 | 一种含有中西医药的阴道模具材料 |
CN103394128A (zh) * | 2013-08-02 | 2013-11-20 | 苏州市马尔泰新材料有限公司 | 一种含有川芎的模具材料 |
CN103431930A (zh) * | 2013-08-02 | 2013-12-11 | 苏州市马尔泰新材料有限公司 | 一种含有甲酯树脂的阴道模具 |
US10137031B2 (en) | 2013-11-14 | 2018-11-27 | International Partnership For Microbicides, Inc. | Combination therapy intravaginal rings |
CN105392454B (zh) * | 2014-06-28 | 2018-05-08 | 安德罗玛克实验室股份有限公司 | 用于预防早产的含有延长、不变和持续释放的孕酮的环扎子宫托 |
CN104546267B (zh) * | 2015-01-13 | 2017-01-04 | 安徽农业大学 | 一种犬用宫外节育装置及其节育方法 |
RU2018126790A (ru) * | 2015-12-21 | 2020-01-23 | Байер Ой | Способ изготовления вагинального кольца |
EP3542786A1 (en) | 2018-03-21 | 2019-09-25 | ITF Research Pharma, S.L.U. | Progesterone intravaginal devices |
US10918649B2 (en) | 2019-06-21 | 2021-02-16 | The Population Council, Inc. | System for providing birth control |
CN113164383B (zh) | 2019-10-12 | 2022-08-12 | 国家卫生健康委科学技术研究所 | 用于黄体支持的阴道缓释给药系统及其制备方法与应用 |
TWI791347B (zh) * | 2020-12-11 | 2023-02-01 | 酷氏基因生物科技股份有限公司 | 一種用於評估胚胎植入成功率的預測方法 |
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