EA201290315A1 - Носитель для доставки - Google Patents

Носитель для доставки

Info

Publication number
EA201290315A1
EA201290315A1 EA201290315A EA201290315A EA201290315A1 EA 201290315 A1 EA201290315 A1 EA 201290315A1 EA 201290315 A EA201290315 A EA 201290315A EA 201290315 A EA201290315 A EA 201290315A EA 201290315 A1 EA201290315 A1 EA 201290315A1
Authority
EA
Eurasian Patent Office
Prior art keywords
present
delivery
carrier
shells
loaded
Prior art date
Application number
EA201290315A
Other languages
English (en)
Inventor
Давид Дельмарре
Мари-Софи Лина Мартина
Ян Эмиль Годеливе Вертоммен
Original Assignee
Кэпсьюджел Белджиум Нв
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Кэпсьюджел Белджиум Нв filed Critical Кэпсьюджел Белджиум Нв
Publication of EA201290315A1 publication Critical patent/EA201290315A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Настоящее изобретение относится к новому жидкому носителю для доставки, включающему в себя конкретную марку каприлата глицерина и ПЭГ-40 гидрогенизированное касторовое масло в определенных количествах. Этот носитель может быть нагружен незначительно или плохо растворимыми в воде веществами и помещен в оболочки твердых желатиновых капсул для окончательного введения субъекту. Также раскрыты наполняющие композиции, включающие в себя такой носитель для доставки, и твердые желатиновые капсулы, наполненные носителем и композицией настоящего изобретения. Носитель для доставки настоящего изобретения является совместимым как с оболочками твердых желатиновых капсул, так и с веществами, которыми он нагружается.
EA201290315A 2009-11-09 2010-10-26 Носитель для доставки EA201290315A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25935509P 2009-11-09 2009-11-09
US37752810P 2010-08-27 2010-08-27
PCT/IB2010/054844 WO2011055269A1 (en) 2009-11-09 2010-10-26 Delivery carrier

Publications (1)

Publication Number Publication Date
EA201290315A1 true EA201290315A1 (ru) 2012-10-30

Family

ID=43416906

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201290315A EA201290315A1 (ru) 2009-11-09 2010-10-26 Носитель для доставки

Country Status (12)

Country Link
US (1) US9333177B2 (ru)
EP (1) EP2498760B1 (ru)
JP (1) JP2013510135A (ru)
KR (1) KR20120105465A (ru)
CN (1) CN102711741A (ru)
AU (1) AU2010316741A1 (ru)
BR (1) BR112012010895A2 (ru)
CA (1) CA2779005A1 (ru)
EA (1) EA201290315A1 (ru)
MX (1) MX2012005264A (ru)
TW (1) TW201119690A (ru)
WO (1) WO2011055269A1 (ru)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8178516B2 (en) * 1992-06-30 2012-05-15 Sylvan Labs, LLC Compositions and method for treatment of chronic inflammatory diseases
GB9525194D0 (en) * 1995-12-12 1996-02-07 Zeneca Ltd Pharmaceutical composition
US5858401A (en) 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
GB9608719D0 (en) * 1996-04-26 1996-07-03 Scherer Ltd R P Pharmaceutical compositions
US5919481A (en) * 1996-06-28 1999-07-06 Ncneil-Ppc, Inc. Fill material for soft gelatin pharmaceutical dosage form
WO1998040051A1 (en) * 1997-03-12 1998-09-17 Abbott Laboratories Lipophilic binary systems for the administration of lipophilic compounds
US20030104048A1 (en) 1999-02-26 2003-06-05 Lipocine, Inc. Pharmaceutical dosage forms for highly hydrophilic materials
US6294192B1 (en) 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6309663B1 (en) 1999-08-17 2001-10-30 Lipocine Inc. Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents
US20030086972A1 (en) * 2000-08-09 2003-05-08 Appel Leah E. Hydrogel-driven drug dosage form
JP4994039B2 (ja) * 2003-11-26 2012-08-08 スパーナス ファーマシューティカルズ インコーポレイテッド 脂溶性または疎水性化合物の送達に有用なミセル系
PE20050596A1 (es) * 2003-12-19 2005-10-18 Novartis Ag Microemulsion que comprende un inhibidor renina
MX2007007038A (es) * 2004-12-09 2008-03-07 Insys Therapeutics Inc Formulacion de dronabinol en temperatura ambiente.
DK2985026T3 (da) * 2005-04-15 2022-10-31 Clarus Therapeutics Inc Farmaceutiske leveringssystemer til hydrofobe lægemidler og sammensætninger dermed
US8252326B2 (en) * 2005-06-01 2012-08-28 Catalent Australia Pty Ltd. Self-microemulsifying dosage forms of low solubility active ingredients such as co-enzyme Q10

Also Published As

Publication number Publication date
TW201119690A (en) 2011-06-16
AU2010316741A1 (en) 2012-05-24
EP2498760B1 (en) 2015-07-01
US9333177B2 (en) 2016-05-10
US20120308655A1 (en) 2012-12-06
BR112012010895A2 (pt) 2019-09-24
CA2779005A1 (en) 2011-05-12
WO2011055269A1 (en) 2011-05-12
EP2498760A1 (en) 2012-09-19
CN102711741A (zh) 2012-10-03
MX2012005264A (es) 2012-07-03
JP2013510135A (ja) 2013-03-21
KR20120105465A (ko) 2012-09-25

Similar Documents

Publication Publication Date Title
MX2013002146A (es) Formulaciones farmaceuticas que utilizan antioxidantes solubles en agua.
CO6290641A2 (es) Preparacion de capsula que contiene los ingredientes farmaceuticamente activos liquidos y solidos, la cual presenta exelentes propiedades de los ingredientes farmaceuticamente activos
HK1182010A1 (en) Liquid pharmaceutical composition for the delivery of active ingredients
EA201290982A1 (ru) Фармацевтические композиции, препятствующие злоупотреблению
CL2011002432A1 (es) Composicion que comprende al menos una enzima digestiva y al menos un portador, en donde el portador comprende celulosa microcristalina que tiene un tamaño de particulas mayor que 100 um; una forma de dosificacion; el envase que la contiene; un proceso para preparar la composicion; y sus usos.
WO2011116963A3 (en) Lipid nanoparticle capsules
BR112013016772B8 (pt) compostos, uso do composto e composição farmacêutica
WO2009149418A3 (en) Compositions for the in vivo delivery of rnai agents
WO2008144061A3 (en) Novel combinations comprising a phosphodiesterase-5 inhibitor and their use
WO2011067667A3 (en) Fexofenadine microcapsules and compositions containing them
EA201591830A1 (ru) Фармацевтические композиции, включающие эверолимус
MX2009005984A (es) Formulaciones con alta concentracion de proteina que contiene manitol.
AR092840A1 (es) Elaboracion de degarelix
MA37645A2 (fr) Formulations stabilisées contenant des anticorps anti-dll4
MX339196B (es) Composiciones de aripiprazol y metodos para su suministro transdermico.
EP2150235A4 (en) Capsule formulation coated with nanoparticles for the purpose of dermal drug administration
WO2012151539A3 (en) Lanthanoid complex capsule and particle contrast agents, methods of making and using thereof
WO2009120885A3 (en) Stabilizing lipid compositions for oral pharmaceutical agents
EA201290315A1 (ru) Носитель для доставки
PE20160850A1 (es) Sistema multiparticulado para administrar drogas
WO2015024577A3 (fr) Composition a base de safranal
MX2013008635A (es) Mejoras de y relacionadas con composiciones.
EA201491995A1 (ru) Пероральная лекарственная форма
WO2009057787A1 (ja) シリカナノカプセル
JP2013510135A5 (ru)