EA201170164A1 - 9-замещенные-в-карбоксиоксадиазинохинолиновые производные, их получение и их применение в качестве антибактериальных средств - Google Patents

9-замещенные-в-карбоксиоксадиазинохинолиновые производные, их получение и их применение в качестве антибактериальных средств

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Publication number
EA201170164A1
EA201170164A1 EA201170164A EA201170164A EA201170164A1 EA 201170164 A1 EA201170164 A1 EA 201170164A1 EA 201170164 A EA201170164 A EA 201170164A EA 201170164 A EA201170164 A EA 201170164A EA 201170164 A1 EA201170164 A1 EA 201170164A1
Authority
EA
Eurasian Patent Office
Prior art keywords
carboxyoxadiazinohinoline
derivatives
substituted
obtaining
antibacterial means
Prior art date
Application number
EA201170164A
Other languages
English (en)
Inventor
Паола Чиапетти
Флоранс Шери-Моцциконаччи
Камилль Ж. Вермют
Сандрин Ропп
Кристоф Морис
Брюно Житлен
Франсуаз Леблан
Марк Шнейдер
Original Assignee
Ветокиноль Са
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ветокиноль Са filed Critical Ветокиноль Са
Publication of EA201170164A1 publication Critical patent/EA201170164A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines having two or more nitrogen atoms in the same ring, e.g. oxadiazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Объектом изобретения являются соединения формулы (I)в которой R, R, R, R', R', R', R, Rи Rявляются такими, как они описаны в заявке, в форме энантиомеров или смесей, а также их солей с кислотами и основаниями, их получение и их применение в качестве антибактериальных средств как в медицине, так и в ветеринарии.
EA201170164A 2008-07-09 2009-06-30 9-замещенные-в-карбоксиоксадиазинохинолиновые производные, их получение и их применение в качестве антибактериальных средств EA201170164A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08290678A EP2145891A1 (en) 2008-07-09 2008-07-09 9-substituted-5-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials
US9841308P 2008-09-19 2008-09-19
PCT/IB2009/006110 WO2010004394A1 (en) 2008-07-09 2009-06-30 9-substituted-b-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials

Publications (1)

Publication Number Publication Date
EA201170164A1 true EA201170164A1 (ru) 2011-12-30

Family

ID=40011090

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201170164A EA201170164A1 (ru) 2008-07-09 2009-06-30 9-замещенные-в-карбоксиоксадиазинохинолиновые производные, их получение и их применение в качестве антибактериальных средств

Country Status (26)

Country Link
US (1) US8071590B2 (ru)
EP (2) EP2145891A1 (ru)
JP (1) JP2011527336A (ru)
KR (1) KR20110038071A (ru)
CN (1) CN102089313A (ru)
AR (1) AR072208A1 (ru)
AT (1) ATE541849T1 (ru)
AU (1) AU2009269735A1 (ru)
BR (1) BRPI0910786A2 (ru)
CA (1) CA2727820A1 (ru)
CL (1) CL2011000041A1 (ru)
CO (1) CO6331342A2 (ru)
CY (1) CY1112729T1 (ru)
DK (1) DK2310395T3 (ru)
EA (1) EA201170164A1 (ru)
ES (1) ES2380906T3 (ru)
HK (1) HK1151521A1 (ru)
HR (1) HRP20120329T1 (ru)
IL (1) IL210013A0 (ru)
MX (1) MX2011000313A (ru)
NZ (1) NZ590367A (ru)
PL (1) PL2310395T3 (ru)
PT (1) PT2310395E (ru)
SI (1) SI2310395T1 (ru)
TW (1) TW201002717A (ru)
WO (1) WO2010004394A1 (ru)

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* Cited by examiner, † Cited by third party
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US8669255B2 (en) * 2011-09-29 2014-03-11 Abbvie Inc. Substituted octahydropyrrolo[1,2-a]pyrazines as calcium channel blockers
CN112672997A (zh) * 2018-07-19 2021-04-16 大日本住友制药株式会社 哒嗪酮衍生物

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US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
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DE4329600A1 (de) * 1993-09-02 1995-03-09 Bayer Ag Pyrido [1,2,3-d,e] [1,3,4] benzoxadiazinderivate
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Also Published As

Publication number Publication date
TW201002717A (en) 2010-01-16
HRP20120329T1 (hr) 2012-05-31
ATE541849T1 (de) 2012-02-15
EP2310395B1 (en) 2012-01-18
PT2310395E (pt) 2012-04-26
IL210013A0 (en) 2011-02-28
HK1151521A1 (ru) 2012-02-03
US8071590B2 (en) 2011-12-06
ES2380906T3 (es) 2012-05-21
AR072208A1 (es) 2010-08-11
SI2310395T1 (sl) 2012-06-29
NZ590367A (en) 2012-08-31
WO2010004394A1 (en) 2010-01-14
AU2009269735A1 (en) 2010-01-14
CL2011000041A1 (es) 2011-07-15
EP2310395A1 (en) 2011-04-20
BRPI0910786A2 (pt) 2017-05-16
KR20110038071A (ko) 2011-04-13
PL2310395T3 (pl) 2012-09-28
DK2310395T3 (da) 2012-04-16
CA2727820A1 (en) 2010-01-14
CY1112729T1 (el) 2016-02-10
US20100009980A1 (en) 2010-01-14
EP2145891A1 (en) 2010-01-20
CN102089313A (zh) 2011-06-08
CO6331342A2 (es) 2011-10-20
JP2011527336A (ja) 2011-10-27
MX2011000313A (es) 2011-06-01

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