EA201070448A1 - Новые композиции на основе таксоидов - Google Patents

Новые композиции на основе таксоидов

Info

Publication number
EA201070448A1
EA201070448A1 EA201070448A EA201070448A EA201070448A1 EA 201070448 A1 EA201070448 A1 EA 201070448A1 EA 201070448 A EA201070448 A EA 201070448A EA 201070448 A EA201070448 A EA 201070448A EA 201070448 A1 EA201070448 A1 EA 201070448A1
Authority
EA
Eurasian Patent Office
Prior art keywords
taxoids
new compositions
basis
formulations
emulsion
Prior art date
Application number
EA201070448A
Other languages
English (en)
Other versions
EA016619B1 (ru
Inventor
Патрисия Рортэ
Карин Гашон
Original Assignee
Авентис Фарма С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Авентис Фарма С.А. filed Critical Авентис Фарма С.А.
Publication of EA201070448A1 publication Critical patent/EA201070448A1/ru
Publication of EA016619B1 publication Critical patent/EA016619B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Epoxy Compounds (AREA)

Abstract

Настоящее изобретение относится к новым композициям на основе таксоидов, представляющим собой инъецируемые составы этих производных в форме эмульсии. Эти составы предназначены для непосредственного внутривенного вливания.
EA201070448A 2007-10-10 2008-10-09 Новые композиции на основе таксоидов EA016619B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0707092A FR2922107B1 (fr) 2007-10-10 2007-10-10 Nouvelles compositions a base de taxoides
PCT/FR2008/001410 WO2009083664A1 (fr) 2007-10-10 2008-10-09 Nouvelles compositions a base de taxoides

Publications (2)

Publication Number Publication Date
EA201070448A1 true EA201070448A1 (ru) 2010-08-30
EA016619B1 EA016619B1 (ru) 2012-06-29

Family

ID=39356621

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201070448A EA016619B1 (ru) 2007-10-10 2008-10-09 Новые композиции на основе таксоидов

Country Status (38)

Country Link
US (1) US8481589B2 (ru)
EP (1) EP2197492B1 (ru)
JP (1) JP5574965B2 (ru)
KR (1) KR20100075490A (ru)
CN (1) CN101820918A (ru)
AR (1) AR072333A1 (ru)
AT (1) ATE534406T1 (ru)
AU (1) AU2008345527A1 (ru)
BR (1) BRPI0818597A2 (ru)
CA (1) CA2701789A1 (ru)
CL (1) CL2008003002A1 (ru)
CO (1) CO6260107A2 (ru)
CR (1) CR11335A (ru)
CY (1) CY1112388T1 (ru)
DK (1) DK2197492T3 (ru)
DO (1) DOP2010000098A (ru)
EA (1) EA016619B1 (ru)
ES (1) ES2377352T3 (ru)
FR (1) FR2922107B1 (ru)
GT (1) GT201000075A (ru)
HR (1) HRP20120165T1 (ru)
IL (1) IL204950A0 (ru)
MA (1) MA31840B1 (ru)
MX (1) MX2010003914A (ru)
NI (1) NI201000048A (ru)
NZ (1) NZ584544A (ru)
PA (1) PA8798101A1 (ru)
PE (1) PE20090962A1 (ru)
PL (1) PL2197492T3 (ru)
PT (1) PT2197492E (ru)
RS (1) RS52131B (ru)
SI (1) SI2197492T1 (ru)
TN (1) TN2010000129A1 (ru)
TW (1) TW200922552A (ru)
UA (1) UA97418C2 (ru)
UY (1) UY31386A1 (ru)
WO (1) WO2009083664A1 (ru)
ZA (1) ZA201002504B (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120065255A1 (en) * 2009-10-19 2012-03-15 Nagesh Palepu Cabazitaxel formulations and methods of preparing thereof
CA2779009A1 (en) 2009-10-29 2011-05-05 Aventis Pharma S.A. Novel antitumoral use of cabazitaxel
KR101752944B1 (ko) 2010-05-03 2017-07-03 테이코쿠 팔마 유에스에이, 인코포레이티드 비수성의 탁산 프로에멀젼 제제, 및 그의 제조 및 사용 방법
JP2012051823A (ja) * 2010-08-31 2012-03-15 Fujifilm Corp 難容性薬物含有水中油型乳化組成物及びその製造方法
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
CN104225615B (zh) * 2014-09-24 2017-02-01 东南大学 一种紫杉醇类磷脂化合物、其药物组合物及应用
EP3384961B1 (en) * 2017-04-05 2021-10-13 RaySearch Laboratories AB System and method for modelling of dose calculation in radiotherapy treatment planning

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750561A (en) 1991-07-08 1998-05-12 Rhone-Poulenc Rorer, S.A. Compositions containing taxane derivatives
FR2678833B1 (fr) 1991-07-08 1995-04-07 Rhone Poulenc Rorer Sa Nouvelles compositions pharmaceutiques a base de derives de la classe des taxanes.
JP3208517B2 (ja) * 1992-07-01 2001-09-17 ブリストル−マイヤーズ スクイブ カンパニー ７，８−シクロプロパタキサン類
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
FR2698543B1 (fr) 1992-12-02 1994-12-30 Rhone Poulenc Rorer Sa Nouvelles compositions à base de taxoides.
US6537579B1 (en) 1993-02-22 2003-03-25 American Bioscience, Inc. Compositions and methods for administration of pharmacologically active compounds
US5415869A (en) * 1993-11-12 1995-05-16 The Research Foundation Of State University Of New York Taxol formulation
US5616330A (en) * 1994-07-19 1997-04-01 Hemagen/Pfc Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same
US6372780B2 (en) * 1995-03-27 2002-04-16 Aventis Pharma S.A. Methods of treating cell lines expressing multidrug resistance P-glycoprotein
JP2002523364A (ja) * 1998-08-20 2002-07-30 アベンテイス・フアルマ・ソシエテ・アノニム タキソイド誘導体の新規な使用
US20020001613A1 (en) * 2000-02-08 2002-01-03 Susan Niemiec Method of manufacturing liposomes
US20030099674A1 (en) 2001-08-11 2003-05-29 Chen Andrew X. Lyophilized injectable formulations containing paclitaxel or other taxoid drugs
CN1794975A (zh) * 2003-04-29 2006-06-28 巴克斯特国际公司 使抗微生物的药物有效抗通常认为抗该药物的生物体的制剂
EP1498143A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Self-emulsifying and self-microemulsifying formulations for the oral administration of taxoids
EP1498120A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Semi-solid formulations for the oral administration of taxoids
US8557861B2 (en) * 2004-09-28 2013-10-15 Mast Therapeutics, Inc. Low oil emulsion compositions for delivering taxoids and other insoluble drugs
JP5089887B2 (ja) * 2006-01-23 2012-12-05 日本精化株式会社 生理活性物質含有複合体

Also Published As

Publication number Publication date
AU2008345527A1 (en) 2009-07-09
EP2197492B1 (fr) 2011-11-23
GT201000075A (es) 2012-04-11
UA97418C2 (ru) 2012-02-10
EA016619B1 (ru) 2012-06-29
NI201000048A (es) 2010-08-20
CR11335A (es) 2010-08-13
NZ584544A (en) 2012-04-27
MA31840B1 (fr) 2010-11-01
WO2009083664A8 (fr) 2010-05-14
EP2197492A1 (fr) 2010-06-23
FR2922107A1 (fr) 2009-04-17
ATE534406T1 (de) 2011-12-15
CY1112388T1 (el) 2015-12-09
BRPI0818597A2 (pt) 2015-04-22
DOP2010000098A (es) 2010-04-30
WO2009083664A1 (fr) 2009-07-09
CN101820918A (zh) 2010-09-01
PL2197492T3 (pl) 2012-05-31
DK2197492T3 (da) 2012-03-12
US8481589B2 (en) 2013-07-09
ZA201002504B (en) 2011-06-29
PA8798101A1 (es) 2009-07-23
FR2922107B1 (fr) 2010-02-26
ES2377352T3 (es) 2012-03-26
CO6260107A2 (es) 2011-03-22
KR20100075490A (ko) 2010-07-02
US20100311825A1 (en) 2010-12-09
SI2197492T1 (sl) 2012-03-30
IL204950A0 (en) 2010-11-30
HRP20120165T1 (hr) 2012-03-31
JP2011500542A (ja) 2011-01-06
AR072333A1 (es) 2010-08-25
TW200922552A (en) 2009-06-01
CA2701789A1 (fr) 2009-07-09
PE20090962A1 (es) 2009-08-10
JP5574965B2 (ja) 2014-08-20
PT2197492E (pt) 2012-02-20
UY31386A1 (es) 2009-05-29
RS52131B (en) 2012-08-31
TN2010000129A1 (fr) 2011-09-26
CL2008003002A1 (es) 2009-10-16
MX2010003914A (es) 2010-05-17

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY RU