EA201001667A1 - Однонуклеотидные полиморфизмы (snp) и связь с устойчивостью к индукции иммунологической толерантности - Google Patents

Однонуклеотидные полиморфизмы (snp) и связь с устойчивостью к индукции иммунологической толерантности

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Publication number
EA201001667A1
EA201001667A1 EA201001667A EA201001667A EA201001667A1 EA 201001667 A1 EA201001667 A1 EA 201001667A1 EA 201001667 A EA201001667 A EA 201001667A EA 201001667 A EA201001667 A EA 201001667A EA 201001667 A1 EA201001667 A1 EA 201001667A1
Authority
EA
Eurasian Patent Office
Prior art keywords
immunological tolerance
nucleotic
snp
polymorphisms
induction
Prior art date
Application number
EA201001667A
Other languages
English (en)
Inventor
Арнолд Э. Послтуэйт
Вэйкуань Гу
Original Assignee
Дзе Юниверсити Ов Теннесси Рисьоч Фаундейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Дзе Юниверсити Ов Теннесси Рисьоч Фаундейшн filed Critical Дзе Юниверсити Ов Теннесси Рисьоч Фаундейшн
Publication of EA201001667A1 publication Critical patent/EA201001667A1/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Steroid Compounds (AREA)

Abstract

В этой заявке раскрыты способы, системы и наборы для коррелирования присутствия или отсутствия определенных нуклеиновокислотных последовательностей в пределах популяции со способностью развития иммунологической толерантности в той же самой популяции. Толерантность может быть индуцирована однократным или повторным введением антигена, в том числе растворимых антигенов, которые вводятся внутривенным или сублингвальным путем. В этой заявке также раскрыты способы обнаружения вариантов. Кроме того, эта заявка направлена на применение или избежание применения нестероидных противовоспалительных лекарственных средств в терапии.
EA201001667A 2008-04-18 2009-04-20 Однонуклеотидные полиморфизмы (snp) и связь с устойчивостью к индукции иммунологической толерантности EA201001667A1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US7126408P 2008-04-18 2008-04-18
US8001208P 2008-07-11 2008-07-11
US10450408P 2008-10-10 2008-10-10
PCT/US2009/041134 WO2009146213A2 (en) 2008-04-18 2009-04-20 Single nucleotide polymorphisms (snp) and association with resistance to immune tolerance induction

Publications (1)

Publication Number Publication Date
EA201001667A1 true EA201001667A1 (ru) 2011-06-30

Family

ID=41377885

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201001667A EA201001667A1 (ru) 2008-04-18 2009-04-20 Однонуклеотидные полиморфизмы (snp) и связь с устойчивостью к индукции иммунологической толерантности

Country Status (12)

Country Link
US (4) US20120135014A1 (ru)
EP (1) EP2286218B1 (ru)
JP (1) JP2011520425A (ru)
KR (1) KR20110014595A (ru)
CN (1) CN102089655A (ru)
AU (1) AU2009251508A1 (ru)
BR (1) BRPI0911104A2 (ru)
CA (1) CA2721651A1 (ru)
EA (1) EA201001667A1 (ru)
IL (1) IL208777A0 (ru)
MX (1) MX2010011445A (ru)
WO (1) WO2009146213A2 (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2970909A4 (en) 2013-03-15 2017-02-15 The University of Chicago Methods and compositions related to t-cell activity
KR102217060B1 (ko) * 2019-01-30 2021-02-18 (주)메디젠휴먼케어 개인별 단일염기 다형성 분석 및 관리 장치
CN111537315B (zh) * 2020-07-13 2020-10-02 天津德祥生物技术有限公司 红细胞膜分离液和红细胞膜分离方法
CN114107474B (zh) * 2020-08-28 2024-05-07 复旦大学附属华山医院 Anxa6多态性位点作为基因标志物以及和甲氨蝶呤联合的银屑病试剂盒
CN113215230B (zh) * 2021-06-22 2024-02-09 艾康健(武汉)基因技术有限公司 一种非疾病诊断目的的snp核酸质谱分型检测方法
CN117904318B (zh) * 2024-01-25 2024-07-12 中国农业科学院兰州畜牧与兽药研究所 一种与藏绵羊免疫性状相关的snp分子标记及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE519115T1 (de) * 2002-06-13 2011-08-15 Merck Patent Gmbh Verfahren für die identifizierung von allo- antigenen und ihre verwendung für krebstherapie und transplantation
US7629164B2 (en) * 2002-10-08 2009-12-08 Affymetrix, Inc. Methods for genotyping polymorphisms in humans
US20040146870A1 (en) * 2003-01-27 2004-07-29 Guochun Liao Systems and methods for predicting specific genetic loci that affect phenotypic traits
CA2519476A1 (en) 2003-03-18 2004-09-30 Applera Corporation Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof
US20080064668A1 (en) * 2003-09-24 2008-03-13 Bioxell S.P.A. 1,3-Diacylated, 26,27-Alkyl/Haloakyl Vitamin D3 Compounds and Methods of Use Thereof
WO2005062770A2 (en) 2003-12-19 2005-07-14 Novakoff James L Method for conducting pharmacogenomics-based studies
MXPA04005080A (es) * 2004-05-27 2005-11-30 Aspid S A De C V Una composicion moduladora de la inflamacion articular cronica a base de colagena-polivinilpirrolidona.
US20060178910A1 (en) * 2005-01-10 2006-08-10 George Eisenberger Publisher gateway systems for collaborative data exchange, collection, monitoring and/or alerting
WO2006075254A2 (en) * 2005-01-13 2006-07-20 Progenika Biopharma, S.A. Methods and products for in vitro genotyping
US20060253263A1 (en) 2005-04-11 2006-11-09 Meshkin Brian J Method to optimize drug selection, dosing and evaluation and to help predict therapeutic response and toxicity from immunosuppressant therapy
US20080070792A1 (en) * 2006-06-14 2008-03-20 Roland Stoughton Use of highly parallel snp genotyping for fetal diagnosis

Also Published As

Publication number Publication date
US20200149108A1 (en) 2020-05-14
BRPI0911104A2 (pt) 2015-10-06
JP2011520425A (ja) 2011-07-21
WO2009146213A3 (en) 2010-02-04
EP2286218A4 (en) 2011-12-28
IL208777A0 (en) 2010-12-30
US20120135014A1 (en) 2012-05-31
KR20110014595A (ko) 2011-02-11
WO2009146213A2 (en) 2009-12-03
CN102089655A (zh) 2011-06-08
CA2721651A1 (en) 2009-12-03
AU2009251508A1 (en) 2009-12-03
US10450610B2 (en) 2019-10-22
EP2286218B1 (en) 2016-04-13
EP2286218A2 (en) 2011-02-23
US20140286971A1 (en) 2014-09-25
MX2010011445A (es) 2011-02-15
US20170016068A1 (en) 2017-01-19

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