EA201000675A1 - Производные хромана как модуляторы trpv3 - Google Patents

Производные хромана как модуляторы trpv3

Info

Publication number
EA201000675A1
EA201000675A1 EA201000675A EA201000675A EA201000675A1 EA 201000675 A1 EA201000675 A1 EA 201000675A1 EA 201000675 A EA201000675 A EA 201000675A EA 201000675 A EA201000675 A EA 201000675A EA 201000675 A1 EA201000675 A1 EA 201000675A1
Authority
EA
Eurasian Patent Office
Prior art keywords
trpv3
chroman derivatives
conditions
modulators
compounds described
Prior art date
Application number
EA201000675A
Other languages
English (en)
Russian (ru)
Inventor
Прасадарао Лингам В.С.
Абрахам Томас
Лаксмикант Атмарам Гхарат
Деепак Виттхал Укирде
Схантарам Кашинат Пхатангаре
Аджит Сханкар Миндхе
Неелима Кхайраткар-Джоши
Видийа Ганапати Каттиге
Original Assignee
Гленмарк Фармасьютикалс, С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Гленмарк Фармасьютикалс, С.А. filed Critical Гленмарк Фармасьютикалс, С.А.
Publication of EA201000675A1 publication Critical patent/EA201000675A1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
EA201000675A 2007-12-18 2008-12-16 Производные хромана как модуляторы trpv3 EA201000675A1 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN2481MU2007 2007-12-18
US1999508P 2008-01-09 2008-01-09
IN647MU2008 2008-03-26
US4393108P 2008-04-10 2008-04-10
PCT/IN2008/000838 WO2009084034A2 (en) 2007-12-18 2008-12-16 Chromane derivatives as trpv3 modulators

Publications (1)

Publication Number Publication Date
EA201000675A1 true EA201000675A1 (ru) 2011-06-30

Family

ID=40824849

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201000675A EA201000675A1 (ru) 2007-12-18 2008-12-16 Производные хромана как модуляторы trpv3

Country Status (10)

Country Link
US (1) US8487121B2 (https=)
EP (1) EP2254879A4 (https=)
JP (1) JP2011519343A (https=)
AU (1) AU2008344922A1 (https=)
CA (1) CA2706566A1 (https=)
EA (1) EA201000675A1 (https=)
GE (1) GEP20125707B (https=)
MX (1) MX2010005704A (https=)
NZ (1) NZ595776A (https=)
WO (1) WO2009084034A2 (https=)

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EP2449112A1 (en) 2009-07-01 2012-05-09 Transposagen Biopharmaceuticals, Inc. Genetically modified rat models for severe combined immunodeficiency (scid)
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
CA2859283C (en) 2011-12-16 2021-03-09 Transposagen Biopharmaceuticals, Inc. Trpc4 modulators for use in the treatment or prevention of pain
MX2017005663A (es) * 2014-10-31 2018-03-01 Abbvie Sarl Tetrahidropiranos sustituidos y metodo de uso.
WO2018118670A1 (en) * 2016-12-20 2018-06-28 Merck Sharp & Dohme Corp. Antidiabetic spirochroman compounds
RU2713946C1 (ru) * 2019-11-13 2020-02-11 Федеральное государственное бюджетное учреждение науки Новосибирский институт органической химии им. Н.Н. Ворожцова Сибирского отделения Российской академии наук (НИОХ СО РАН) 4,7-диметил-3,4,4a,5,8,8a-гексагидроспиро[хромен-2,1'-циклогексан]-4,8-диол в качестве анальгезирующего средства
KR20250091305A (ko) * 2022-11-10 2025-06-20 프라임 진 테라퓨틱스 컴퍼니 리미티드 질소 함유 스피로 고리 화합물, 약학 조성물 및 이의 용도
CN120882726A (zh) * 2022-12-26 2025-10-31 阳光安津(南京)生物医药科技有限公司 包括杂芳环的化合物及其组合物和方法

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WO2009084034A2 (en) 2009-07-09
CA2706566A1 (en) 2009-07-09
GEP20125707B (en) 2012-12-10
WO2009084034A3 (en) 2012-01-19
JP2011519343A (ja) 2011-07-07
AU2008344922A2 (en) 2012-04-26
EP2254879A2 (en) 2010-12-01
US20100311778A1 (en) 2010-12-09
EP2254879A4 (en) 2012-10-31
MX2010005704A (es) 2010-08-17
NZ595776A (en) 2013-08-30
US8487121B2 (en) 2013-07-16
AU2008344922A1 (en) 2012-01-19

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