EA200700847A1 - Материалы, связывающие прионные белки, и способы их применения - Google Patents
Материалы, связывающие прионные белки, и способы их примененияInfo
- Publication number
- EA200700847A1 EA200700847A1 EA200700847A EA200700847A EA200700847A1 EA 200700847 A1 EA200700847 A1 EA 200700847A1 EA 200700847 A EA200700847 A EA 200700847A EA 200700847 A EA200700847 A EA 200700847A EA 200700847 A1 EA200700847 A1 EA 200700847A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- prion protein
- methods
- materials
- prional
- proteins
- Prior art date
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
- B01J20/26—Synthetic macromolecular compounds
- B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/282—Porous sorbents
- B01J20/285—Porous sorbents based on polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3206—Organic carriers, supports or substrates
- B01J20/3208—Polymeric carriers, supports or substrates
- B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
- B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
- B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
- B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
- B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
- B01J20/3251—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising at least two different types of heteroatoms selected from nitrogen, oxygen or sulphur
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
- B01J20/3257—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur together with at least one silicon atom, these atoms not being part of the carrier as such
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
- B01J20/3293—Coatings on a core, the core being particle or fiber shaped, e.g. encapsulated particles, coated fibers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
- B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Предложены материалы, связывающие прионный белок, и способы применения связывающих материалов для обнаружения или удаления прионного белка из образца, такого как биологическая жидкость или образец из внешней среды. Связывающие материалы способны связывать одну или несколько форм прионного белка, включая клеточный прионный белок (PrPc), инфекционный прионный белок (PrPsc), рекомбинантный прионный белок (PrPr) и устойчивый к протеазе прионный белок (PrPres). Связывающие материалы связывают прионы различных видов, включая людей и хомяков.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/962,670 US7510848B2 (en) | 2003-04-04 | 2004-10-13 | Prion protein binding materials and methods of use |
PCT/US2005/036676 WO2006044459A2 (en) | 2004-10-13 | 2005-10-13 | Prion protein binding materials and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
EA200700847A1 true EA200700847A1 (ru) | 2007-10-26 |
Family
ID=36145798
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200700847A EA200700847A1 (ru) | 2004-10-13 | 2005-10-13 | Материалы, связывающие прионные белки, и способы их применения |
Country Status (17)
Country | Link |
---|---|
US (1) | US7510848B2 (ru) |
EP (1) | EP1802322A4 (ru) |
JP (1) | JP4897689B2 (ru) |
KR (1) | KR20070117533A (ru) |
CN (1) | CN101065136A (ru) |
AP (1) | AP2007003974A0 (ru) |
AU (1) | AU2005295773B2 (ru) |
BR (1) | BRPI0515970A (ru) |
CA (1) | CA2582462C (ru) |
EA (1) | EA200700847A1 (ru) |
IL (1) | IL182422A0 (ru) |
MA (1) | MA29004B1 (ru) |
MX (1) | MX2007004399A (ru) |
NO (1) | NO20072427L (ru) |
TN (1) | TNSN07136A1 (ru) |
WO (1) | WO2006044459A2 (ru) |
ZA (1) | ZA200702634B (ru) |
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JP4235544B2 (ja) | 2001-05-31 | 2009-03-11 | アドライフ インコーポレーティッド | 欠陥折畳み蛋白質センサー方法 |
US20050026165A1 (en) | 2001-05-31 | 2005-02-03 | Cindy Orser | Detection of conformationally altered proteins and prions |
ES2375958T3 (es) * | 2002-12-03 | 2012-03-07 | Pathogen Removal And Diagnostic Technologies, Inc. | Ligandos de prote�?nas priones y procedimientos de uso. |
US20060057671A1 (en) * | 2004-09-10 | 2006-03-16 | Orser Cindy S | Immobilized probes and methods of detecting conformationally altered prion proteins |
WO2006088823A2 (en) * | 2005-02-15 | 2006-08-24 | Adlyfe, Inc. | Method for detecting misfolded proteins and prions |
WO2008013859A2 (en) * | 2006-07-28 | 2008-01-31 | Adlyfe, Inc. | Peptide probes for diagnostics and therapeutics |
US20100227794A1 (en) * | 2008-11-26 | 2010-09-09 | I.S.T. Corporation | Smart contrast agent and method for detecting transition metal ions and treating related disorders |
US20100129290A1 (en) * | 2008-11-26 | 2010-05-27 | I.S.T. Corporation | Smart contrast agent and detection method for detecting transition metal ions |
KR20120044279A (ko) | 2009-04-15 | 2012-05-07 | 아브락시스 바이오사이언스, 엘엘씨 | 무-프리온 나노입자 조성물 및 방법 |
JP2013535683A (ja) | 2010-07-30 | 2013-09-12 | イー・エム・デイー・ミリポア・コーポレイシヨン | クロマトグラフィー媒体及び方法 |
EP2619569B1 (en) * | 2010-09-24 | 2018-05-23 | GE Healthcare Bio-Sciences AB | Wetting of a plastic bed support for a chromatography column |
EP2771087A4 (en) * | 2011-10-28 | 2015-06-10 | Glycorex Transplantation Ab | METHOD FOR THE EXTRACORPOREAL REMOVAL OF ONE OR MORE CONSTITUENTS FROM BLOOD |
KR101363575B1 (ko) * | 2012-08-07 | 2014-02-24 | 가천대학교 산학협력단 | 신부전증에 대한 신규 바이오마커 및 그의 용도 |
KR101363576B1 (ko) * | 2012-08-07 | 2014-02-24 | 가천대학교 산학협력단 | 알츠하이머 질환에 대한 신규 바이오마커 및 그의 용도 |
CN103336124B (zh) * | 2012-12-11 | 2015-07-15 | 武汉工业学院 | 一种检测朊病毒蛋白(PrPSC)的方法和试剂盒 |
CA2954425C (en) | 2014-09-02 | 2019-05-07 | Emd Millipore Corporation | High surface area fiber media with nano-fibrillated surface features |
US20170298091A1 (en) | 2014-12-08 | 2017-10-19 | Emd Millipore Corporation | Mixed Bed Ion Exchange Adsorber |
CA2993235A1 (en) * | 2015-07-30 | 2017-02-02 | North Carolina State University | Grafted islands-in-the-sea nonwoven for high capacity ion exchange bioseparation |
JP6701338B2 (ja) | 2015-08-10 | 2020-05-27 | エッセンリックス コーポレーション | ステップが簡略化され、試料が少なく、スピードアップし、使いやすい、生化学的/化学的なアッセイ装置及び方法 |
EP3341724B1 (en) | 2015-09-14 | 2023-10-04 | Essenlix Corporation | Device and system for collecting and analyzing vapor condensate, particularly exhaled breath condensate, as well as method of using the same |
CA2998587C (en) | 2015-09-14 | 2023-01-10 | Essenlix Corp. | Device and system for analyzing a sample, particularly blood, as well as methods of using the same |
US10628693B2 (en) | 2016-12-21 | 2020-04-21 | Essenlix Corporation | Devices and methods for authenticating a sample and use of the same |
CN111246945A (zh) | 2017-02-07 | 2020-06-05 | Essenlix公司 | 压缩开放流测定和使用 |
CA3053002A1 (en) | 2017-02-08 | 2018-08-16 | Essenlix Corp. | Bio/chemical material extraction and assay |
WO2018148607A1 (en) | 2017-02-09 | 2018-08-16 | Essenlix Corporation | Assay using different spacing heights |
WO2018148609A2 (en) | 2017-02-09 | 2018-08-16 | Essenlix Corporation | Colorimetric assays |
CA3053132A1 (en) | 2017-02-09 | 2018-08-16 | Essenlix Corp. | Assay with amplification |
CA3053301A1 (en) | 2017-02-16 | 2018-08-23 | Essenlix Corporation | Assay with textured surface |
CN111492222A (zh) | 2017-08-01 | 2020-08-04 | Essenlix公司 | 样品收集、保持和测定 |
US11725227B2 (en) | 2017-08-01 | 2023-08-15 | Essenlix Corporation | Devices and methods for examining drug effects on microorganisms |
US11280706B2 (en) | 2017-08-01 | 2022-03-22 | Essenlix Corporation | Dilution calibration |
US11393561B2 (en) | 2017-10-13 | 2022-07-19 | Essenlix Corporation | Devices and methods for authenticating a medical test and use of the same |
US11237113B2 (en) | 2017-10-26 | 2022-02-01 | Essenlix Corporation | Rapid pH measurement |
US11609224B2 (en) | 2017-10-26 | 2023-03-21 | Essenlix Corporation | Devices and methods for white blood cell analyses |
US10807095B2 (en) | 2017-10-26 | 2020-10-20 | Essenlix Corporation | Making and tracking assay card |
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CN112534259A (zh) | 2017-12-14 | 2021-03-19 | Essenlix公司 | 监测毛发的装置,系统和方法 |
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US11885952B2 (en) | 2018-07-30 | 2024-01-30 | Essenlix Corporation | Optics, device, and system for assaying and imaging |
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2004
- 2004-10-13 US US10/962,670 patent/US7510848B2/en active Active
-
2005
- 2005-10-13 WO PCT/US2005/036676 patent/WO2006044459A2/en active Application Filing
- 2005-10-13 JP JP2007536839A patent/JP4897689B2/ja not_active Expired - Fee Related
- 2005-10-13 EP EP05810556A patent/EP1802322A4/en not_active Withdrawn
- 2005-10-13 CA CA2582462A patent/CA2582462C/en not_active Expired - Fee Related
- 2005-10-13 AU AU2005295773A patent/AU2005295773B2/en not_active Ceased
- 2005-10-13 EA EA200700847A patent/EA200700847A1/ru unknown
- 2005-10-13 AP AP2007003974A patent/AP2007003974A0/xx unknown
- 2005-10-13 BR BRPI0515970-9A patent/BRPI0515970A/pt not_active Application Discontinuation
- 2005-10-13 CN CNA200580035169XA patent/CN101065136A/zh active Pending
- 2005-10-13 MX MX2007004399A patent/MX2007004399A/es active IP Right Grant
- 2005-10-13 KR KR1020077010675A patent/KR20070117533A/ko not_active Application Discontinuation
-
2007
- 2007-03-29 ZA ZA200702634A patent/ZA200702634B/xx unknown
- 2007-04-10 IL IL182422A patent/IL182422A0/en unknown
- 2007-04-13 TN TNP2007000136A patent/TNSN07136A1/fr unknown
- 2007-05-04 MA MA29867A patent/MA29004B1/fr unknown
- 2007-05-11 NO NO20072427A patent/NO20072427L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
BRPI0515970A (pt) | 2007-12-18 |
US7510848B2 (en) | 2009-03-31 |
TNSN07136A1 (en) | 2008-11-21 |
AU2005295773B2 (en) | 2011-06-09 |
CN101065136A (zh) | 2007-10-31 |
CA2582462A1 (en) | 2006-04-27 |
MX2007004399A (es) | 2007-04-25 |
MA29004B1 (fr) | 2007-11-01 |
WO2006044459A3 (en) | 2006-07-13 |
WO2006044459A2 (en) | 2006-04-27 |
CA2582462C (en) | 2013-08-06 |
JP4897689B2 (ja) | 2012-03-14 |
AU2005295773A1 (en) | 2006-04-27 |
AP2007003974A0 (en) | 2007-06-30 |
NO20072427L (no) | 2007-07-04 |
EP1802322A4 (en) | 2009-07-22 |
KR20070117533A (ko) | 2007-12-12 |
EP1802322A2 (en) | 2007-07-04 |
IL182422A0 (en) | 2007-07-24 |
ZA200702634B (en) | 2008-09-25 |
JP2008516260A (ja) | 2008-05-15 |
US20060078892A1 (en) | 2006-04-13 |
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