EA200601665A1 - Комбинация дерамциклана и опиоидов в качестве обезболивающего средства - Google Patents

Комбинация дерамциклана и опиоидов в качестве обезболивающего средства

Info

Publication number
EA200601665A1
EA200601665A1 EA200601665A EA200601665A EA200601665A1 EA 200601665 A1 EA200601665 A1 EA 200601665A1 EA 200601665 A EA200601665 A EA 200601665A EA 200601665 A EA200601665 A EA 200601665A EA 200601665 A1 EA200601665 A1 EA 200601665A1
Authority
EA
Eurasian Patent Office
Prior art keywords
analgesic
deramcyclan
opioids
combination
morphine
Prior art date
Application number
EA200601665A
Other languages
English (en)
Other versions
EA010691B1 (ru
Inventor
Иштван Гачальи
Габор Гиглер
Ласло Габор Харсинг
Дьёрдь Леваи
Габор Сенаши
Original Assignee
Эгиш Дьёдьсердьяр Нирт.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эгиш Дьёдьсердьяр Нирт. filed Critical Эгиш Дьёдьсердьяр Нирт.
Publication of EA200601665A1 publication Critical patent/EA200601665A1/ru
Publication of EA010691B1 publication Critical patent/EA010691B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Изобретение относится к комбинированной обезболивающей фармацевтической композиции, которая содержит (1R,2S,4R)-(-)-2-[N,N-(диметиламиноэтокси)]-2-фенил-1,7,7-триметилбицикло[2.2.1]гептан или его фармацевтически приемлемую кислотно-аддитивную соль в качестве компонента А) и морфин, анальгетик опиоидного типа и/или анальгетик неопиоидного типа в качестве компонента В) в смеси с фармацевтически приемлемыми носителями и/или вспомогательными веществами. Дерамциклан усиливает обезболивающий эффект морфина.
EA200601665A 2004-03-12 2004-03-12 Комбинация дерамциклана и опиоидов в качестве обезболивающего средства EA010691B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/HU2004/000021 WO2005087213A1 (en) 2004-03-12 2004-03-12 Combination of deramciclane and opoids as analgesics

Publications (2)

Publication Number Publication Date
EA200601665A1 true EA200601665A1 (ru) 2007-04-27
EA010691B1 EA010691B1 (ru) 2008-10-30

Family

ID=34957272

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200601665A EA010691B1 (ru) 2004-03-12 2004-03-12 Комбинация дерамциклана и опиоидов в качестве обезболивающего средства

Country Status (19)

Country Link
US (1) US20070244102A1 (ru)
EP (1) EP1734940B1 (ru)
JP (1) JP2007528891A (ru)
CN (1) CN1946386A (ru)
AT (1) ATE410156T1 (ru)
AU (1) AU2004317128A1 (ru)
BR (1) BRPI0418631A (ru)
CA (1) CA2559487A1 (ru)
CZ (1) CZ2006623A3 (ru)
DE (1) DE602004017062D1 (ru)
EA (1) EA010691B1 (ru)
HR (1) HRP20060325A2 (ru)
IL (1) IL177734A0 (ru)
IS (1) IS8546A (ru)
MX (1) MXPA06010388A (ru)
NO (1) NO20064645L (ru)
RS (1) RS20060504A (ru)
SK (1) SK50812006A3 (ru)
WO (1) WO2005087213A1 (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU231055B1 (hu) * 2015-10-09 2020-04-28 Egis Gyógyszergyár Zrt. Deramciklan és nem-szteroid gyulladásgátló gyógyszerek kombinációjának alkalmazása jobb gyulladáscsökkentő hatás elérésére
HU230962B1 (hu) * 2015-10-28 2019-06-28 Egis Gyógyszergyár Zrt. Palbociclib sók
US11478467B2 (en) 2017-05-04 2022-10-25 Sreenivasarao Vepachedu Targeted drug rescue with novel compositions, combinations, and methods thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5652270A (en) * 1994-07-01 1997-07-29 Egis Gyogyszergyar Rt Pharmaceutical compositions containing bicycloheptane ether amines and a process for the preparation thereof
HU226061B1 (en) * 1996-10-17 2008-04-28 Egis Gyogyszergyar Nyilvanosan 1,7,7-trimethyl-bicyclo[2.2.1]heptane derivative, pharmaceutical compositions containing the same and process for their preparation
HU227114B1 (en) * 1999-05-11 2010-07-28 Egis Gyogyszergyar Nyilvanosan (1r, 2s, 4r)-(-)-2-[n,n-(dimethylamino-ethoxy)]-2-phenyl-1,7,7-trimethyl-bicyclo[2.2.1]heptane of high purity and pharmaceutically acceptable acid addition salts thereof, process for preparation of them and medicaments containing the same
HUP0103017A3 (en) * 2001-07-18 2004-05-28 Egis Gyogyszergyar Nyilvanosan Pharmaceutical composition for the treatment of diseases caused by impairment of cognitive functions and its use

Also Published As

Publication number Publication date
WO2005087213A1 (en) 2005-09-22
EP1734940B1 (en) 2008-10-08
SK50812006A3 (sk) 2007-03-01
MXPA06010388A (es) 2007-03-07
BRPI0418631A (pt) 2007-05-29
IL177734A0 (en) 2006-12-31
HRP20060325A2 (en) 2007-02-28
CZ2006623A3 (cs) 2007-01-24
CN1946386A (zh) 2007-04-11
EP1734940A1 (en) 2006-12-27
NO20064645L (no) 2006-12-08
AU2004317128A1 (en) 2005-09-22
EA010691B1 (ru) 2008-10-30
DE602004017062D1 (de) 2008-11-20
CA2559487A1 (en) 2005-09-22
IS8546A (is) 2006-10-03
RS20060504A (en) 2008-09-29
ATE410156T1 (de) 2008-10-15
US20070244102A1 (en) 2007-10-18
JP2007528891A (ja) 2007-10-18

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU