EA200600439A1 - 4- ((феноксиалкил)тио) феноксиуксусные кислоты и аналоги - Google Patents
4- ((феноксиалкил)тио) феноксиуксусные кислоты и аналогиInfo
- Publication number
- EA200600439A1 EA200600439A1 EA200600439A EA200600439A EA200600439A1 EA 200600439 A1 EA200600439 A1 EA 200600439A1 EA 200600439 A EA200600439 A EA 200600439A EA 200600439 A EA200600439 A EA 200600439A EA 200600439 A1 EA200600439 A1 EA 200600439A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- phenoxyl
- analogues
- acids
- thyo
- phenoxyalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
- C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/20—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/08—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/12—1,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Abstract
Изобретение относится к 4-((феноксиалкил)тио)феноксиуксусным кислотам и аналогам, включающим их композициям и способам их применения в качестве модуляторов PPAR-дельта для лечения или ингибирования прогрессирования, например дислипидемии.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50408903P | 2003-09-19 | 2003-09-19 | |
PCT/US2004/030188 WO2005030694A1 (en) | 2003-09-19 | 2004-09-16 | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200600439A1 true EA200600439A1 (ru) | 2006-08-25 |
EA009119B1 EA009119B1 (ru) | 2007-10-26 |
Family
ID=34392924
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200600439A EA009119B1 (ru) | 2003-09-19 | 2004-09-16 | 4-((феноксиалкил)тио)феноксиуксусные кислоты и аналоги |
Country Status (31)
Country | Link |
---|---|
US (4) | US7598292B2 (ru) |
EP (2) | EP1670744B9 (ru) |
JP (1) | JP5016922B2 (ru) |
KR (1) | KR101094742B1 (ru) |
CN (1) | CN1882524B (ru) |
AR (1) | AR045774A1 (ru) |
AT (1) | ATE476408T1 (ru) |
AU (1) | AU2004276231B2 (ru) |
BR (1) | BRPI0414534B8 (ru) |
CA (1) | CA2539403C (ru) |
CO (1) | CO5680473A2 (ru) |
CR (1) | CR8303A (ru) |
CY (2) | CY1110847T1 (ru) |
DE (1) | DE602004028500D1 (ru) |
DK (2) | DK1670744T5 (ru) |
EA (1) | EA009119B1 (ru) |
EC (1) | ECSP066435A (ru) |
ES (2) | ES2349143T3 (ru) |
HK (1) | HK1093060A1 (ru) |
HU (1) | HUE028213T2 (ru) |
IL (1) | IL174399A (ru) |
NO (1) | NO337041B1 (ru) |
NZ (1) | NZ545971A (ru) |
PL (2) | PL2243766T3 (ru) |
PT (2) | PT2243766E (ru) |
SG (1) | SG149041A1 (ru) |
SI (2) | SI1670744T1 (ru) |
TW (1) | TWI330630B (ru) |
UA (1) | UA87468C2 (ru) |
WO (1) | WO2005030694A1 (ru) |
ZA (1) | ZA200603084B (ru) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI1667964T1 (sl) | 2003-09-19 | 2009-12-31 | Janssen Pharmaceutica Nv | 4-((fenoksialkil)tio)-fenoksiocetne kisline in analogi |
MY147518A (en) * | 2004-09-15 | 2012-12-31 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
MY145712A (en) * | 2004-09-15 | 2012-03-30 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
JO3006B1 (ar) * | 2005-09-14 | 2016-09-05 | Janssen Pharmaceutica Nv | املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك |
UY30288A1 (es) * | 2006-04-18 | 2007-08-31 | Janssen Pharmaceutica Nv | Derivados del ácido benzoazepin-oxi-acético como agonistas de ppar-delta usados para aumentar hdl-c. reducir ldl-c y reducir colesterol |
EP2612669A4 (en) | 2010-08-31 | 2014-05-14 | Snu R&Db Foundation | USING THE FÖTAL REPROGRAMMING OF A PPAR AGONIST |
CN103183612A (zh) * | 2011-12-30 | 2013-07-03 | 北大方正集团有限公司 | 二丙基丙二酸二酯的制备方法 |
SG11201404475TA (en) | 2012-02-10 | 2014-08-28 | Lupin Ltd | Antiviral compounds with a dibenzooxaheterocycle moiety |
CN106188097B (zh) * | 2016-07-08 | 2018-01-05 | 郑州大学 | 一种3‑氯甲基氧头孢烯类抗生素母核的制备方法 |
PL3522880T3 (pl) * | 2016-10-05 | 2021-08-23 | Mitobridge, Inc. | Sposoby leczenia ostrego uszkodzenia nerek |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4125732A (en) * | 1977-05-06 | 1978-11-14 | American Cyanamid Company | 2-Aryloxy-2-(phenoxyalkoxy)phenyl acetic acid and esters |
DE3169761D1 (en) | 1981-01-09 | 1985-05-09 | Fisons Plc | Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them |
JPS58177934A (ja) | 1982-04-13 | 1983-10-18 | Takeda Chem Ind Ltd | ベンゾキノン誘導体 |
ATE22072T1 (de) * | 1982-09-30 | 1986-09-15 | Merck Frosst Canada Inc | Leukotrienantagonisten, deren herstellung und diese enthaltende zusammensetzungen. |
US4820867A (en) * | 1983-04-21 | 1989-04-11 | Merck Frosst Canada, Inc. | Phenoxypropoxy halophenylacetic acids as leukotriene antagonists |
JPS61268651A (ja) * | 1985-05-23 | 1986-11-28 | Takeda Chem Ind Ltd | フエニル酢酸誘導体およびその製造法 |
US5726165A (en) * | 1994-07-29 | 1998-03-10 | Smithkline Beecham P.L.C. | Derivatives of 4-(2-aminoethyl)phenoxymethyl-phosphonic and -phosphinic acid and pharmaceutical and veterinary uses therefor |
ATE293963T1 (de) * | 1996-02-02 | 2005-05-15 | Merck & Co Inc | Verfahren zur behandlung von diabetes und verwandter krankheitszustände. |
JP3373198B2 (ja) | 1997-12-19 | 2003-02-04 | メルク エンド カムパニー インコーポレーテッド | アリールチアゾリジンジオン誘導体 |
US6399640B1 (en) * | 1999-06-18 | 2002-06-04 | Merck & Co., Inc. | Arylthiazolidinedione and aryloxazolidinedione derivatives |
GB9914977D0 (en) | 1999-06-25 | 1999-08-25 | Glaxo Group Ltd | Chemical compounds |
GB0003310D0 (en) * | 2000-02-15 | 2000-04-05 | Univ Sheffield | Bone formation |
RU2004105956A (ru) * | 2001-07-30 | 2005-03-27 | Ново Нордиск А/С (DK) | Новые производные винилкарбоновых кислот и их применение в качестве антидиабетических средств и т.п. |
JP4383177B2 (ja) * | 2002-03-01 | 2009-12-16 | スミスクライン ビーチャム コーポレーション | hPPAR活性化剤 |
JP2007502815A (ja) * | 2003-08-20 | 2007-02-15 | イーライ リリー アンド カンパニー | Ppar調節因子 |
SI1667964T1 (sl) | 2003-09-19 | 2009-12-31 | Janssen Pharmaceutica Nv | 4-((fenoksialkil)tio)-fenoksiocetne kisline in analogi |
MY147518A (en) | 2004-09-15 | 2012-12-31 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
MY145712A (en) | 2004-09-15 | 2012-03-30 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
JO3006B1 (ar) * | 2005-09-14 | 2016-09-05 | Janssen Pharmaceutica Nv | املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك |
-
2004
- 2004-09-16 DE DE602004028500T patent/DE602004028500D1/de active Active
- 2004-09-16 KR KR1020067007361A patent/KR101094742B1/ko active IP Right Grant
- 2004-09-16 SI SI200431520T patent/SI1670744T1/sl unknown
- 2004-09-16 PL PL10008042T patent/PL2243766T3/pl unknown
- 2004-09-16 SG SG200809395-7A patent/SG149041A1/en unknown
- 2004-09-16 PL PL04784146T patent/PL1670744T3/pl unknown
- 2004-09-16 EP EP04784146A patent/EP1670744B9/en active Active
- 2004-09-16 BR BRPI0414534A patent/BRPI0414534B8/pt active IP Right Grant
- 2004-09-16 PT PT100080423T patent/PT2243766E/pt unknown
- 2004-09-16 PT PT04784146T patent/PT1670744E/pt unknown
- 2004-09-16 ES ES04784146T patent/ES2349143T3/es active Active
- 2004-09-16 HU HUE10008042A patent/HUE028213T2/en unknown
- 2004-09-16 EA EA200600439A patent/EA009119B1/ru unknown
- 2004-09-16 NZ NZ545971A patent/NZ545971A/en unknown
- 2004-09-16 UA UAA200603108A patent/UA87468C2/ru unknown
- 2004-09-16 WO PCT/US2004/030188 patent/WO2005030694A1/en active Application Filing
- 2004-09-16 CN CN2004800337382A patent/CN1882524B/zh active Active
- 2004-09-16 DK DK04784146.5T patent/DK1670744T5/da active
- 2004-09-16 JP JP2006526992A patent/JP5016922B2/ja active Active
- 2004-09-16 SI SI200432276T patent/SI2243766T1/sl unknown
- 2004-09-16 ES ES10008042.3T patent/ES2555031T3/es active Active
- 2004-09-16 EP EP10008042.3A patent/EP2243766B1/en active Active
- 2004-09-16 US US10/942,563 patent/US7598292B2/en active Active
- 2004-09-16 AU AU2004276231A patent/AU2004276231B2/en active Active
- 2004-09-16 CA CA2539403A patent/CA2539403C/en active Active
- 2004-09-16 AT AT04784146T patent/ATE476408T1/de active
- 2004-09-16 DK DK10008042.3T patent/DK2243766T3/en active
- 2004-09-17 TW TW093127865A patent/TWI330630B/zh active
- 2004-09-20 AR ARP040103377A patent/AR045774A1/es active IP Right Grant
-
2006
- 2006-03-17 EC EC2006006435A patent/ECSP066435A/es unknown
- 2006-03-19 IL IL174399A patent/IL174399A/en active IP Right Grant
- 2006-03-20 CR CR8303A patent/CR8303A/es unknown
- 2006-03-30 CO CO06031467A patent/CO5680473A2/es active IP Right Grant
- 2006-04-18 ZA ZA200603084A patent/ZA200603084B/en unknown
- 2006-04-19 NO NO20061711A patent/NO337041B1/no unknown
- 2006-12-15 HK HK06113838.3A patent/HK1093060A1/xx unknown
-
2009
- 2009-08-28 US US12/549,431 patent/US8008513B2/en active Active
-
2010
- 2010-10-18 CY CY20101100933T patent/CY1110847T1/el unknown
-
2011
- 2011-08-11 US US13/207,809 patent/US8258177B2/en active Active
-
2012
- 2012-08-29 US US13/597,316 patent/US8450371B2/en active Active
-
2015
- 2015-11-06 CY CY20151100994T patent/CY1117666T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EA200600440A1 (ru) | 4-((феноксиалкил)тио)еноксиуксусные кислоты и их аналоги | |
EA200700648A1 (ru) | 4-((феноксиалкил)тио)феноксиуксусные кислоты и аналоги | |
EA200601553A1 (ru) | Замещенные бензимидазол-, бензтриазол- и бензимидазолон-о-глюкозиды | |
EA200700647A1 (ru) | 4-((феноксиалкил)тио)феноксиуксусные кислоты и аналоги | |
SE0301010D0 (sv) | Novel compounds | |
CY1112653T1 (el) | Κρυσταλλικες τροποποιησεις της πυρακλοστροβινης | |
EA201300242A1 (ru) | Фармацевтические композиции, содержащие замещенные ациланилиды | |
SE0301009D0 (sv) | Novel compounds | |
SE0301653D0 (sv) | Novel compounds | |
EA200701396A1 (ru) | Триазолофталазины в качестве ингибиторов pde-2 | |
DE602006019468D1 (de) | Diarylharnstoffe zur behandlung von pulmonaler hypertonie | |
ATE460923T1 (de) | Lyophilisierung von virosomen | |
RS51271B (sr) | Čvrsta farmaceutska kompozicija koja sadrži donepezil hidrohlorid | |
CY1110847T1 (el) | 4-((φαινοξυαλκυλο)θειο)-φαινοξυ-οξικα οξεα και αναλογα | |
DK1237549T3 (da) | Lipoxin A4 og dets analoger til behandling af törre öjne | |
PA8575601A1 (es) | Procedimiento para su preparacion, medicamentos que comprenden estos compuestos y su uso | |
DE602005021625D1 (de) | Haarbehandlungszusammensetzungen | |
ATE472316T1 (de) | Haarbehandlungszusammensetzungen | |
DE60316128D1 (de) | N-sulfonylurea-apoptosis-förderer | |
ATE391489T1 (de) | Haarbehandlungszusammensetzungen | |
SE0500291L (sv) | New composition and the use thereof |