EA200300842A1 - Новая соль тиазолидиндиона и ее полиморфные формы в качестве противодиабетических средств и способ их получения - Google Patents
Новая соль тиазолидиндиона и ее полиморфные формы в качестве противодиабетических средств и способ их полученияInfo
- Publication number
- EA200300842A1 EA200300842A1 EA200300842A EA200300842A EA200300842A1 EA 200300842 A1 EA200300842 A1 EA 200300842A1 EA 200300842 A EA200300842 A EA 200300842A EA 200300842 A EA200300842 A EA 200300842A EA 200300842 A1 EA200300842 A1 EA 200300842A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- polymorphic forms
- thiazolidindion
- diabetic
- preparation
- new salt
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- 230000003178 anti-diabetic effect Effects 0.000 title 1
- 239000003472 antidiabetic agent Substances 0.000 title 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 2
- YFSDOQBVZCZKDZ-UHFFFAOYSA-N 5-[[4-[2-[(6-methoxypyrimidin-4-yl)methylamino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione Chemical compound C1=NC(OC)=CC(CNCCOC=2C=CC(CC3C(NC(=O)S3)=O)=CC=2)=N1 YFSDOQBVZCZKDZ-UHFFFAOYSA-N 0.000 abstract 1
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 230000003345 hyperglycaemic effect Effects 0.000 abstract 1
- 201000001421 hyperglycemia Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
Данное изобретение относится к новой соли 5-(4-{2-[(6-метоксипиримидин-4-ил)метиламино]этокси}бензил)тиазолидин-2,4-диона и ее полиморфным формам, которые обладают высокой гипергликемической активностью и которые поэтому потенциально пригодны для лечения и/или профилактики диабета и/или других изменений или компликаций, свойственных диабету, таких как гипергликемия или гиперлипидемия. Данное изобретение также относится к способу их получения.Международная заявка была опубликована вместе с отчетом о международном поиске.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200100273A ES2174748B1 (es) | 2001-01-31 | 2001-01-31 | Nueva sal de tiazolidindiona y sus polimorfos como agentes antidiabeticos y procedimiento para la obtencion de los mismos. |
| PCT/IB2002/000229 WO2002060899A1 (en) | 2001-01-31 | 2002-01-21 | New salt of thiazolidinedione and its polymorphs as antidiabetic agents and method for obtaining them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA200300842A1 true EA200300842A1 (ru) | 2004-04-29 |
Family
ID=8496644
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200300842A EA200300842A1 (ru) | 2001-01-31 | 2002-01-21 | Новая соль тиазолидиндиона и ее полиморфные формы в качестве противодиабетических средств и способ их получения |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US20040106632A1 (ru) |
| EP (1) | EP1355908A1 (ru) |
| JP (1) | JP2004529870A (ru) |
| KR (1) | KR20030078893A (ru) |
| CN (1) | CN1694881A (ru) |
| AP (1) | AP1281A (ru) |
| AR (1) | AR042584A1 (ru) |
| BG (1) | BG108047A (ru) |
| BR (1) | BR0206850A (ru) |
| CA (1) | CA2436556A1 (ru) |
| CZ (1) | CZ20032015A3 (ru) |
| EA (1) | EA200300842A1 (ru) |
| EE (1) | EE200300356A (ru) |
| ES (1) | ES2174748B1 (ru) |
| HU (1) | HUP0302871A2 (ru) |
| IL (1) | IL157028A0 (ru) |
| IS (1) | IS6896A (ru) |
| MA (1) | MA26988A1 (ru) |
| MX (1) | MXPA03006722A (ru) |
| NO (1) | NO20033375L (ru) |
| NZ (1) | NZ527677A (ru) |
| PE (1) | PE20020969A1 (ru) |
| PL (1) | PL362527A1 (ru) |
| SK (1) | SK9552003A3 (ru) |
| WO (1) | WO2002060899A1 (ru) |
| YU (1) | YU60303A (ru) |
| ZA (1) | ZA200305873B (ru) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0842925A1 (en) * | 1987-09-04 | 1998-05-20 | Beecham Group Plc | Substituted thiazolidinedione derivatives |
| CN1183130C (zh) * | 1999-09-24 | 2005-01-05 | 中国人民解放军军事医学科学院毒物药物研究所 | 噻唑烷类衍生物及其医药用途 |
| ES2156574B1 (es) * | 1999-11-18 | 2002-02-01 | Vita Invest Sa | Nuevos derivados de tiazolidindiona como agentes antidiabeticos |
-
2001
- 2001-01-31 ES ES200100273A patent/ES2174748B1/es not_active Expired - Fee Related
-
2002
- 2002-01-21 US US10/470,980 patent/US20040106632A1/en not_active Abandoned
- 2002-01-21 KR KR10-2003-7009880A patent/KR20030078893A/ko not_active Application Discontinuation
- 2002-01-21 WO PCT/IB2002/000229 patent/WO2002060899A1/en not_active Application Discontinuation
- 2002-01-21 MX MXPA03006722A patent/MXPA03006722A/es not_active Application Discontinuation
- 2002-01-21 EA EA200300842A patent/EA200300842A1/ru unknown
- 2002-01-21 PL PL02362527A patent/PL362527A1/xx not_active Application Discontinuation
- 2002-01-21 BR BR0206850-8A patent/BR0206850A/pt not_active IP Right Cessation
- 2002-01-21 CN CNA028043863A patent/CN1694881A/zh active Pending
- 2002-01-21 CA CA002436556A patent/CA2436556A1/en not_active Abandoned
- 2002-01-21 EP EP02716216A patent/EP1355908A1/en not_active Withdrawn
- 2002-01-21 HU HU0302871A patent/HUP0302871A2/hu unknown
- 2002-01-21 ZA ZA200305873A patent/ZA200305873B/en unknown
- 2002-01-21 JP JP2002561467A patent/JP2004529870A/ja active Pending
- 2002-01-21 NZ NZ527677A patent/NZ527677A/en unknown
- 2002-01-21 CZ CZ20032015A patent/CZ20032015A3/cs unknown
- 2002-01-21 IL IL15702802A patent/IL157028A0/xx unknown
- 2002-01-21 SK SK955-2003A patent/SK9552003A3/sk not_active Application Discontinuation
- 2002-01-21 EE EEP200300356A patent/EE200300356A/xx unknown
- 2002-01-21 AP APAP/P/2003/002832A patent/AP1281A/en active
- 2002-01-21 YU YU60303A patent/YU60303A/sh unknown
- 2002-01-24 PE PE2002000054A patent/PE20020969A1/es not_active Application Discontinuation
- 2002-01-28 AR ARP020100291A patent/AR042584A1/es not_active Application Discontinuation
-
2003
- 2003-07-28 IS IS6896A patent/IS6896A/is unknown
- 2003-07-28 NO NO20033375A patent/NO20033375L/no not_active Application Discontinuation
- 2003-07-31 MA MA27262A patent/MA26988A1/fr unknown
- 2003-08-01 BG BG108047A patent/BG108047A/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AP1281A (en) | 2004-05-25 |
| ZA200305873B (en) | 2004-07-30 |
| YU60303A (sh) | 2006-05-25 |
| BG108047A (bg) | 2004-08-31 |
| BR0206850A (pt) | 2004-01-13 |
| ES2174748B1 (es) | 2003-09-16 |
| NZ527677A (en) | 2005-01-28 |
| WO2002060899A1 (en) | 2002-08-08 |
| MA26988A1 (fr) | 2004-12-20 |
| NO20033375L (no) | 2003-08-22 |
| CZ20032015A3 (cs) | 2004-02-18 |
| US20040106632A1 (en) | 2004-06-03 |
| EP1355908A1 (en) | 2003-10-29 |
| MXPA03006722A (es) | 2004-10-15 |
| ES2174748A1 (es) | 2002-11-01 |
| AP2003002832A0 (en) | 2003-09-30 |
| CN1694881A (zh) | 2005-11-09 |
| NO20033375D0 (no) | 2003-07-28 |
| IL157028A0 (en) | 2004-02-08 |
| PE20020969A1 (es) | 2002-12-04 |
| EE200300356A (et) | 2003-10-15 |
| PL362527A1 (en) | 2004-11-02 |
| IS6896A (is) | 2003-07-28 |
| JP2004529870A (ja) | 2004-09-30 |
| KR20030078893A (ko) | 2003-10-08 |
| HUP0302871A2 (hu) | 2003-12-29 |
| AR042584A1 (es) | 2005-06-29 |
| SK9552003A3 (en) | 2004-05-04 |
| CA2436556A1 (en) | 2002-08-08 |
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