EA200201258A1 - Способ лучевой терапии - Google Patents
Способ лучевой терапииInfo
- Publication number
- EA200201258A1 EA200201258A1 EA200201258A EA200201258A EA200201258A1 EA 200201258 A1 EA200201258 A1 EA 200201258A1 EA 200201258 A EA200201258 A EA 200201258A EA 200201258 A EA200201258 A EA 200201258A EA 200201258 A1 EA200201258 A1 EA 200201258A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- bone
- radiation therapy
- tumors
- human
- subject
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Radiation-Therapy Devices (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
Abstract
Согласно данному изобретению предложен способ лучевой терапии субъекта млекопитающего, являющегося человеком или не человеком, включающий введение указанному субъекту терапевтического, профилактического или облегчающего боль количества обеспечивающего направленную доставку к кости комплекса испускающего альфа-частицы радионуклида тория или актиния, например для лечения кальцифицированных опухолей, костных опухолей, костей, костных поверхностей и мягких тканей.Отчет о международном поиске был опубликован 2002.09.06.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO20003457A NO313180B1 (no) | 2000-07-04 | 2000-07-04 | Bensökende alfapartikkel emitterende radiofarmasöytika |
PCT/GB2001/002996 WO2002005859A2 (en) | 2000-07-04 | 2001-07-04 | Radiotherapy |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200201258A1 true EA200201258A1 (ru) | 2003-06-26 |
EA004899B1 EA004899B1 (ru) | 2004-08-26 |
Family
ID=19911348
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200201258A EA004899B1 (ru) | 2000-07-04 | 2001-07-04 | Способ лучевой терапии |
Country Status (15)
Country | Link |
---|---|
US (2) | US7056275B2 (ru) |
EP (1) | EP1296722B1 (ru) |
JP (1) | JP5219325B2 (ru) |
KR (1) | KR100892002B1 (ru) |
AT (1) | ATE305313T1 (ru) |
AU (2) | AU6773401A (ru) |
CA (1) | CA2413736C (ru) |
CZ (1) | CZ299087B6 (ru) |
DE (1) | DE60113683T2 (ru) |
DK (1) | DK1296722T3 (ru) |
EA (1) | EA004899B1 (ru) |
ES (1) | ES2250419T3 (ru) |
NO (1) | NO313180B1 (ru) |
PL (1) | PL206209B1 (ru) |
WO (1) | WO2002005859A2 (ru) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO310544B1 (no) * | 1999-01-04 | 2001-07-23 | Algeta As | Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben |
NO314537B1 (no) * | 1999-12-06 | 2003-04-07 | Anticancer Therapeutic Inv Sa | Reseptorbindende konjugater |
EP1227849A2 (en) * | 2000-02-25 | 2002-08-07 | Dangshe Ma | Actinium-225 complexes and conjugates for radioimmunotherapy |
NO313180B1 (no) * | 2000-07-04 | 2002-08-26 | Anticancer Therapeutic Inv Sa | Bensökende alfapartikkel emitterende radiofarmasöytika |
US6670456B2 (en) | 2001-02-28 | 2003-12-30 | Dow Global Technologies Inc. | Actinium-225 complexes and conjugates for targeted radiotherapy |
GB0308731D0 (en) * | 2003-04-15 | 2003-05-21 | Anticancer Therapeutic Inv Sa | Method of radiotherapy |
ES2486845T3 (es) * | 2003-04-15 | 2014-08-19 | Algeta Asa | Torio-227 para ser usado en radioterapia de enfermedad de partes blandas |
US8142758B2 (en) * | 2004-02-20 | 2012-03-27 | Algeta As | Alpha-emitting hydroxyapatite particles |
EP2497501B1 (en) * | 2004-06-25 | 2019-05-01 | The European Union, represented by the European Commission | Radionuclides for medical use |
LU91085B1 (en) * | 2004-06-25 | 2005-12-27 | European Community | Radionuclides for medical use. |
US7794691B2 (en) | 2004-06-25 | 2010-09-14 | The European Community, Represented By The European Commission | Radionuclides for medical use |
GB0423565D0 (en) * | 2004-10-22 | 2004-11-24 | Algeta As | Formulation |
US8709380B1 (en) * | 2006-02-07 | 2014-04-29 | Sirius Medicine, Llc | Targeting agents for enhancing radiation therapy |
CA2659251C (en) | 2006-07-10 | 2016-06-14 | The Regents Of The University Of California | Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides |
FR2913970B1 (fr) * | 2007-03-19 | 2009-06-12 | Cogema | Production de thorium 228 a partir d'un sel de thorium naturel |
US20080249398A1 (en) * | 2007-04-09 | 2008-10-09 | Harder George Fred | Hybrid Source Containing Multi-Radionuclides for Use in Radiation Therapy |
WO2011025790A1 (en) | 2009-08-24 | 2011-03-03 | Lumiphore, Inc. | Macrocyclic hopo chelators |
EP3263562A1 (en) * | 2009-12-24 | 2018-01-03 | Lumiphore, Inc. | Radiopharmaceutical complexes |
US9202602B2 (en) * | 2010-02-10 | 2015-12-01 | Uchicago Argonne, Llc | Production of isotopes using high power proton beams |
GB201002508D0 (en) | 2010-02-12 | 2010-03-31 | Algeta As | Product |
GB201208309D0 (en) | 2012-05-11 | 2012-06-27 | Algeta As | Complexes |
US11453652B2 (en) | 2013-03-15 | 2022-09-27 | Lumiphore, Inc. | Di-macrocycles |
GB201314718D0 (en) * | 2013-08-16 | 2013-10-02 | Algeta As | Quantification method |
GB201600158D0 (en) * | 2016-01-05 | 2016-02-17 | Bayer As | Purification method |
GB201600154D0 (en) * | 2016-01-05 | 2016-02-17 | Bayer As | Isotope preparation method |
GB201600161D0 (en) | 2016-01-05 | 2016-02-17 | Bayer As | Isotope purification method |
AU2017239018A1 (en) | 2016-03-24 | 2018-08-16 | Bayer As | Radio-pharmaceutical complexes |
SG11201810967VA (en) | 2016-06-10 | 2019-01-30 | Bayer Pharma AG | Radio-pharmaceutical complexes |
RU2763750C2 (ru) | 2017-05-11 | 2022-01-10 | Альфа Тау Медикал Лтд. | Полимерные покрытия для брахитерапевтических устройств |
CA3094785A1 (en) | 2018-04-02 | 2019-10-10 | Alpha Tau Medical Ltd. | Controlled release of radionuclides |
FR3088769B1 (fr) * | 2018-11-15 | 2020-12-25 | Orano Med | Procede de preparation d'au moins un generateur a haute teneur en radium-228 |
US20220152228A1 (en) * | 2019-03-01 | 2022-05-19 | Washington University | Compositions and methods for radiotherapy using chelated radiotherapeutic agents and non-target tissue blockade |
AR119479A1 (es) | 2019-07-25 | 2021-12-22 | Bayer As | Radiofármacos dirigidos para diagnóstico y tratamiento de cáncer |
RU2767567C1 (ru) * | 2020-10-27 | 2022-03-17 | Станислав Анатольевич Дороватовский | Комплексные соединения, содержащие в своем составе радионуклид 227Th, а также бисфосфонатный фрагмент, способы их получения, а также потенциальное применение в качестве действующего вещества в составе остеотропного радиофармацевтического лекарственного препарата |
US11857803B2 (en) | 2020-12-16 | 2024-01-02 | Alpha Tau Medical Ltd. | Diffusing alpha-emitter radiation therapy with enhanced beta treatment |
KR102545315B1 (ko) | 2021-01-05 | 2023-06-20 | 한국과학기술원 | 의료용 방사성 동위원소의 생산 방법 및 시스템 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2329147A (en) * | 1938-05-07 | 1943-09-07 | Rare Chemicals Inc | Stabilized metal sol and method of preparing same |
US4560548A (en) * | 1984-04-10 | 1985-12-24 | The Dow Chemical Company | Bone seeking Tc-99m complexes of phosphonate derivatives of bis(aminoalkyl)piperazine |
US4882142A (en) * | 1988-12-19 | 1989-11-21 | The Dow Chemical Company | Bone marrow suppressing agents |
US5192526A (en) * | 1989-05-02 | 1993-03-09 | Mallinckrodt Medical, Inc. | Kit for preparation of rhenium therapeutic agents for bone cancer without purification |
LU87684A1 (de) * | 1990-02-23 | 1991-10-08 | Euratom | Verfahren zur erzeugung von aktinium-225 und wismut-213 |
US5902825A (en) * | 1997-01-07 | 1999-05-11 | Mitreoak, Ltd. | Composition and method for the palliation of pain associated with diseases of the bone and bone joints |
FI104901B (fi) * | 1997-10-20 | 2000-04-28 | Leiras Oy | Uudet metyleenibisfosfonihappojohdannaiset |
NO310544B1 (no) * | 1999-01-04 | 2001-07-23 | Algeta As | Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben |
AU5871000A (en) * | 1999-06-11 | 2001-01-02 | Paul G. Abrams | High dose radionuclide complexes for bone marrow suppression |
NO314537B1 (no) * | 1999-12-06 | 2003-04-07 | Anticancer Therapeutic Inv Sa | Reseptorbindende konjugater |
NO312708B1 (no) * | 2000-02-21 | 2002-06-24 | Anticancer Therapeutic Inv Sa | Radioaktive liposomer til terapi |
EP1227849A2 (en) * | 2000-02-25 | 2002-08-07 | Dangshe Ma | Actinium-225 complexes and conjugates for radioimmunotherapy |
NO313180B1 (no) * | 2000-07-04 | 2002-08-26 | Anticancer Therapeutic Inv Sa | Bensökende alfapartikkel emitterende radiofarmasöytika |
US6548042B2 (en) * | 2000-08-07 | 2003-04-15 | Arstad Erik | Bis-phosphonate compounds |
US6670456B2 (en) * | 2001-02-28 | 2003-12-30 | Dow Global Technologies Inc. | Actinium-225 complexes and conjugates for targeted radiotherapy |
GB0213261D0 (en) * | 2002-06-10 | 2002-07-17 | Anticancer Therapeutic Inv Sa | Method |
US20030086868A1 (en) * | 2002-08-12 | 2003-05-08 | Dangshe Ma | Actinium-225 complexes and conjugates for radioimmunotherapy |
US20060228297A1 (en) * | 2003-04-15 | 2006-10-12 | Roy Larsen | Thorium-227 for use in radiotherapy of soft tissue disease |
GB0308731D0 (en) * | 2003-04-15 | 2003-05-21 | Anticancer Therapeutic Inv Sa | Method of radiotherapy |
-
2000
- 2000-07-04 NO NO20003457A patent/NO313180B1/no not_active IP Right Cessation
-
2001
- 2001-07-04 KR KR1020037000060A patent/KR100892002B1/ko not_active IP Right Cessation
- 2001-07-04 AU AU6773401A patent/AU6773401A/xx active Pending
- 2001-07-04 DE DE60113683T patent/DE60113683T2/de not_active Expired - Lifetime
- 2001-07-04 DK DK01945519T patent/DK1296722T3/da active
- 2001-07-04 US US10/332,056 patent/US7056275B2/en not_active Expired - Fee Related
- 2001-07-04 CA CA002413736A patent/CA2413736C/en not_active Expired - Fee Related
- 2001-07-04 CZ CZ20030334A patent/CZ299087B6/cs not_active IP Right Cessation
- 2001-07-04 AT AT01945519T patent/ATE305313T1/de active
- 2001-07-04 AU AU2001267734A patent/AU2001267734B2/en not_active Ceased
- 2001-07-04 ES ES01945519T patent/ES2250419T3/es not_active Expired - Lifetime
- 2001-07-04 WO PCT/GB2001/002996 patent/WO2002005859A2/en active IP Right Grant
- 2001-07-04 EP EP01945519A patent/EP1296722B1/en not_active Expired - Lifetime
- 2001-07-04 JP JP2002511790A patent/JP5219325B2/ja not_active Expired - Fee Related
- 2001-07-04 EA EA200201258A patent/EA004899B1/ru not_active IP Right Cessation
- 2001-07-04 PL PL366070A patent/PL206209B1/pl unknown
-
2006
- 2006-01-23 US US11/337,385 patent/US7335154B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE305313T1 (de) | 2005-10-15 |
EA004899B1 (ru) | 2004-08-26 |
EP1296722B1 (en) | 2005-09-28 |
US7056275B2 (en) | 2006-06-06 |
KR100892002B1 (ko) | 2009-04-07 |
AU2001267734B2 (en) | 2005-09-01 |
US7335154B2 (en) | 2008-02-26 |
US20060135842A1 (en) | 2006-06-22 |
DE60113683T2 (de) | 2006-07-06 |
NO20003457L (no) | 2002-01-07 |
NO313180B1 (no) | 2002-08-26 |
JP2004503331A (ja) | 2004-02-05 |
EP1296722A2 (en) | 2003-04-02 |
PL206209B1 (pl) | 2010-07-30 |
DE60113683D1 (en) | 2006-02-09 |
JP5219325B2 (ja) | 2013-06-26 |
ES2250419T3 (es) | 2006-04-16 |
NO20003457D0 (no) | 2000-07-04 |
CA2413736C (en) | 2009-08-18 |
WO2002005859A3 (en) | 2002-09-06 |
AU6773401A (en) | 2002-01-30 |
KR20030029100A (ko) | 2003-04-11 |
PL366070A1 (en) | 2005-01-24 |
WO2002005859A2 (en) | 2002-01-24 |
DK1296722T3 (da) | 2006-02-13 |
CZ299087B6 (cs) | 2008-04-23 |
US20030166989A1 (en) | 2003-09-04 |
CA2413736A1 (en) | 2002-01-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |