EA200200370A1 - Препараты эстрамустинфосфата и сульфоалкиловых эфиров циклодекстринов для парентерального применения - Google Patents

Препараты эстрамустинфосфата и сульфоалкиловых эфиров циклодекстринов для парентерального применения

Info

Publication number
EA200200370A1
EA200200370A1 EA200200370A EA200200370A EA200200370A1 EA 200200370 A1 EA200200370 A1 EA 200200370A1 EA 200200370 A EA200200370 A EA 200200370A EA 200200370 A EA200200370 A EA 200200370A EA 200200370 A1 EA200200370 A1 EA 200200370A1
Authority
EA
Eurasian Patent Office
Prior art keywords
estramustinphosphate
sulphoalkyl
cyclodextrines
preparations
esters
Prior art date
Application number
EA200200370A
Other languages
English (en)
Other versions
EA003936B1 (ru
Inventor
Лорена Муджетти
Паоло Коломбо
Алессандро Мартини
Джованни Буцци
Original Assignee
Фармация Италия С.П.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фармация Италия С.П.А. filed Critical Фармация Италия С.П.А.
Publication of EA200200370A1 publication Critical patent/EA200200370A1/ru
Publication of EA003936B1 publication Critical patent/EA003936B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Фармацевтический препарат, включающий носитель или разбавитель, приемлемый для парентерального применения, эстрамустинфосфат и сульфоалкиловый эфир циклодекстрина. Данный препарат можно принимать согласно схеме комбинированной химиотерапии совместно с одним или большим количеством химиотерапевтических агентов. Данный препарат также дает возможность вводить эстрамустинфосфат без побочных эффектов в месте инъекции.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200200370A 1999-09-16 2000-08-03 Препараты эстрамустинфосфата и сульфоалкиловых эфиров циклодекстринов для парентерального применения EA003936B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9921958.6A GB9921958D0 (en) 1999-09-16 1999-09-16 Formulations for parenteral use of estramustine phosphate and sulfoalkylether-cyclodextrins
PCT/EP2000/007680 WO2001019339A1 (en) 1999-09-16 2000-08-03 Formulations for parenteral use of estramustine phosphate and sulfoalkyl ether cyclodextrins

Publications (2)

Publication Number Publication Date
EA200200370A1 true EA200200370A1 (ru) 2002-10-31
EA003936B1 EA003936B1 (ru) 2003-10-30

Family

ID=10861068

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200370A EA003936B1 (ru) 1999-09-16 2000-08-03 Препараты эстрамустинфосфата и сульфоалкиловых эфиров циклодекстринов для парентерального применения

Country Status (19)

Country Link
US (1) US6730664B1 (ru)
EP (1) EP1212041A1 (ru)
JP (1) JP2003509356A (ru)
KR (1) KR20020059401A (ru)
CN (1) CN1374857A (ru)
AU (1) AU777684B2 (ru)
BR (1) BR0014062A (ru)
CA (1) CA2385065A1 (ru)
CZ (1) CZ2002944A3 (ru)
EA (1) EA003936B1 (ru)
GB (1) GB9921958D0 (ru)
HU (1) HUP0300185A3 (ru)
IL (1) IL148408A0 (ru)
MX (1) MXPA02002855A (ru)
NO (1) NO20021270L (ru)
PL (1) PL356026A1 (ru)
SK (1) SK3462002A3 (ru)
WO (1) WO2001019339A1 (ru)
ZA (1) ZA200201744B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6869939B2 (en) * 2002-05-04 2005-03-22 Cydex, Inc. Formulations containing amiodarone and sulfoalkyl ether cyclodextrin
US7658913B2 (en) 2005-11-28 2010-02-09 Verrow Pharmaceuticals, Inc. Compositions useful for reducing nephrotoxicity and methods of use thereof
ES2473665T3 (es) * 2005-11-28 2014-07-07 Verrow Pharmaceuticals, Inc. Composiciones útiles para reducir la nefrotoxicidad y los métodos de uso de las mismas
US20110207764A1 (en) * 2010-02-23 2011-08-25 Valery Alakhov Cyclopolysaccharide compositions
US8383663B2 (en) 2010-07-19 2013-02-26 Supratek Pharma Inc. Bendamustine anionic-catioinic cyclopolysaccharide compositions
WO2024074600A1 (en) * 2022-10-05 2024-04-11 Institut Gustave Roussy An oral liquid composition of vinorelbine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523035A (en) * 1976-03-10 1978-08-31 Leo Ab Derivatives of estradiol - 17 - dihydrogen phosphates
JPS59108800A (ja) 1982-12-13 1984-06-23 Japan Atom Energy Res Inst 誘導ミサイル作用および制癌剤の徐放性機能をもつ微粒子
CA1260393A (en) * 1984-10-16 1989-09-26 Lajos Tarcsay Liposomes of synthetic lipids
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5602112A (en) 1992-06-19 1997-02-11 Supergen, Inc. Pharmaceutical formulation
GB9419153D0 (en) * 1994-09-22 1994-11-09 Erba Carlo Spa Estramustine formulations with improved pharmaceutical properties
US5744460A (en) * 1996-03-07 1998-04-28 Novartis Corporation Combination for treatment of proliferative diseases
US20020039594A1 (en) 1997-05-13 2002-04-04 Evan C. Unger Solid porous matrices and methods of making and using the same

Also Published As

Publication number Publication date
EA003936B1 (ru) 2003-10-30
AU777684B2 (en) 2004-10-28
JP2003509356A (ja) 2003-03-11
CA2385065A1 (en) 2001-03-22
GB9921958D0 (en) 1999-11-17
IL148408A0 (en) 2002-09-12
BR0014062A (pt) 2002-12-31
PL356026A1 (en) 2004-05-31
MXPA02002855A (es) 2003-07-21
HUP0300185A3 (en) 2007-02-28
EP1212041A1 (en) 2002-06-12
NO20021270D0 (no) 2002-03-14
NO20021270L (no) 2002-03-14
SK3462002A3 (en) 2002-08-06
CN1374857A (zh) 2002-10-16
HUP0300185A2 (en) 2003-05-28
AU6993900A (en) 2001-04-17
WO2001019339A1 (en) 2001-03-22
US6730664B1 (en) 2004-05-04
CZ2002944A3 (cs) 2002-08-14
KR20020059401A (ko) 2002-07-12
ZA200201744B (en) 2004-01-28

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU