EA200200319A1 - Белок iren, его получение и использование - Google Patents

Белок iren, его получение и использование

Info

Publication number
EA200200319A1
EA200200319A1 EA200200319A EA200200319A EA200200319A1 EA 200200319 A1 EA200200319 A1 EA 200200319A1 EA 200200319 A EA200200319 A EA 200200319A EA 200200319 A EA200200319 A EA 200200319A EA 200200319 A1 EA200200319 A1 EA 200200319A1
Authority
EA
Eurasian Patent Office
Prior art keywords
production
iren protein
traf
iren
protein
Prior art date
Application number
EA200200319A
Other languages
English (en)
Other versions
EA005775B1 (ru
Inventor
Дэвид Уоллах
Николай Малинин
Индранил Синха
Стефан Леу
Original Assignee
Йеда Рисерч Энд Дивелопмент Ко.Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Йеда Рисерч Энд Дивелопмент Ко.Лтд. filed Critical Йеда Рисерч Энд Дивелопмент Ко.Лтд.
Publication of EA200200319A1 publication Critical patent/EA200200319A1/ru
Publication of EA005775B1 publication Critical patent/EA005775B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Описаны ДНК-последовательности, кодирующие TRAF-связывающие белки, белки, кодируемые этими последовательностями, и их использование для лечения или профилактики патологических состояний, связанных с индукцией NF=кВ или с активностью, опосредованной TRAF.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200200319A 1999-09-02 2000-08-31 Белок iren, его получение и использование EA005775B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL13171999A IL131719A0 (en) 1999-09-02 1999-09-02 Iren protein its preparation and use
PCT/IL2000/000517 WO2001016314A1 (en) 1999-09-02 2000-08-31 Iren protein, its preparation and use

Publications (2)

Publication Number Publication Date
EA200200319A1 true EA200200319A1 (ru) 2002-08-29
EA005775B1 EA005775B1 (ru) 2005-06-30

Family

ID=11073213

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200319A EA005775B1 (ru) 1999-09-02 2000-08-31 Белок iren, его получение и использование

Country Status (17)

Country Link
US (2) US7429648B1 (ru)
EP (1) EP1208197A1 (ru)
JP (1) JP2003508053A (ru)
KR (1) KR100820526B1 (ru)
CN (1) CN100482795C (ru)
AR (1) AR025482A1 (ru)
AU (1) AU784582B2 (ru)
BR (1) BR0014167A (ru)
CA (1) CA2383606A1 (ru)
EA (1) EA005775B1 (ru)
EE (1) EE200200096A (ru)
HK (1) HK1051876A1 (ru)
IL (2) IL131719A0 (ru)
MX (1) MXPA02002391A (ru)
NO (1) NO20020919L (ru)
WO (1) WO2001016314A1 (ru)
ZA (1) ZA200201401B (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4429726B2 (ja) * 2002-02-08 2010-03-10 ワイス 炎症性応答を調節するための組成物および方法
AU2003234840A1 (en) * 2002-05-29 2003-12-12 Anges Mg, Inc. Decoy composition for treating and preventing inflammatory disease
US8400998B2 (en) 2006-08-23 2013-03-19 Motorola Mobility Llc Downlink control channel signaling in wireless communication systems
WO2014165769A1 (en) * 2013-04-05 2014-10-09 Mo Bio Laboratories, Inc. Kits and methods for isolating protein from biological and environmental samples
CN105985979B (zh) * 2015-02-12 2020-03-24 上海交通大学 一种用于高通量受体基因筛查的新型膜蛋白酵母双杂交方法
CN105986001B (zh) * 2015-02-12 2019-12-03 上海交通大学 一种基于膜结合蛋白和荧光互补的高通量猎物拮抗剂筛选方法
WO2017040992A1 (en) 2015-09-04 2017-03-09 Mo Bio Laboratories, Inc. Methods for co-isolation of nucelic acids and proteins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA71889C2 (ru) * 1996-04-02 2005-01-17 Йєда Рісерч Енд Дівелопмент Ко. Лтд. Translated By PlajМОДУЛЯТОРЫ СВЯЗАННОГО С РЕЦЕПТОРОМ TNF ФАКТОРА (TRAF), ИХ ПОЛУЧЕНИЕ И ПРИМЕНЕНИЕ
KR100552547B1 (ko) * 1996-04-02 2006-05-12 에다 리서치 앤드 디벨럽먼트 컴퍼니 리미티드 Tnf수용체연합된인자(traf)조절물질,이의제조및이의용도

Also Published As

Publication number Publication date
MXPA02002391A (es) 2002-08-20
WO2001016314A1 (en) 2001-03-08
BR0014167A (pt) 2002-05-07
CN1384878A (zh) 2002-12-11
US7429648B1 (en) 2008-09-30
KR100820526B1 (ko) 2008-04-07
AU784582B2 (en) 2006-05-04
CN100482795C (zh) 2009-04-29
JP2003508053A (ja) 2003-03-04
IL131719A0 (en) 2001-03-19
NO20020919L (no) 2002-04-25
EP1208197A1 (en) 2002-05-29
NO20020919D0 (no) 2002-02-25
EE200200096A (et) 2003-04-15
HK1051876A1 (en) 2003-08-22
AU6723100A (en) 2001-03-26
KR20020059386A (ko) 2002-07-12
CA2383606A1 (en) 2001-03-08
US20090075889A1 (en) 2009-03-19
EA005775B1 (ru) 2005-06-30
IL148446A0 (en) 2002-09-12
ZA200201401B (en) 2003-05-28
AR025482A1 (es) 2002-11-27

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU