EA199800732A1 - СПОСОБ ОЧИСТКИ 11b-21-ДИГИДРОКСИ-2 '-МЕТИЛ-5' b Н-ПРЕГНА-1,4-ДИЕНО - (17,16-ди)-ОКСАЗОЛ-3,20-ДИОНА - Google Patents

СПОСОБ ОЧИСТКИ 11b-21-ДИГИДРОКСИ-2 '-МЕТИЛ-5' b Н-ПРЕГНА-1,4-ДИЕНО - (17,16-ди)-ОКСАЗОЛ-3,20-ДИОНА

Info

Publication number
EA199800732A1
EA199800732A1 EA199800732A EA199800732A EA199800732A1 EA 199800732 A1 EA199800732 A1 EA 199800732A1 EA 199800732 A EA199800732 A EA 199800732A EA 199800732 A EA199800732 A EA 199800732A EA 199800732 A1 EA199800732 A1 EA 199800732A1
Authority
EA
Eurasian Patent Office
Prior art keywords
dieno
pregna
methyl
dihydroxi
diona
Prior art date
Application number
EA199800732A
Other languages
English (en)
Other versions
EA000789B1 (ru
Inventor
Луиджи Форте
Original Assignee
Группо Лепетит С.П.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Группо Лепетит С.П.А. filed Critical Группо Лепетит С.П.А.
Publication of EA199800732A1 publication Critical patent/EA199800732A1/ru
Publication of EA000789B1 publication Critical patent/EA000789B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0057—Nitrogen and oxygen
    • C07J71/0068—Nitrogen and oxygen at position 16(17)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Способ очистки соединения 11β-21-дигидрокси-2'-метил-5'βН-прегна-1,4-диено(17, 16-ди-)оксазолин-3,20-дион формулы Iвключающий адсорбцию вышеуказанного соединения, содержащегося в водном растворе, который образуется из ферментационного бульона или из потоков в ходе процесса на адсорбционной полимерной смоле, имеющей стирольный или акриловый матриксы, и затем десорбцию вышеуказанного соединения при помощи элюции смолы подходящей смесью воды с водорастворимым органическим растворителем.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199800732A 1996-02-16 1996-12-04 СПОСОБ ОЧИСТКИ 11β-21-ДИГИДРОКСИ-2'-МЕТИЛ-5'βН-ПРЕГНА-1,4-ДИЕНО-(17,16-ди)-ОКСАЗОЛ-3,20-ДИОНА EA000789B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96102325 1996-02-16
PCT/EP1996/005392 WO1997030068A1 (en) 1996-02-16 1996-12-04 PROCESS FOR THE PURIFICATION OF 11β-21-DIHYDROXY-2'-METHYL-5'βH-PREGNA-1,4-DIENO[17,16-D]OXAZOLE-3,20-DIONE

Publications (2)

Publication Number Publication Date
EA199800732A1 true EA199800732A1 (ru) 1999-02-25
EA000789B1 EA000789B1 (ru) 2000-04-24

Family

ID=8222483

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199800732A EA000789B1 (ru) 1996-02-16 1996-12-04 СПОСОБ ОЧИСТКИ 11β-21-ДИГИДРОКСИ-2'-МЕТИЛ-5'βН-ПРЕГНА-1,4-ДИЕНО-(17,16-ди)-ОКСАЗОЛ-3,20-ДИОНА

Country Status (21)

Country Link
US (1) US6228851B1 (ru)
EP (1) EP0885240B1 (ru)
JP (1) JP4076098B2 (ru)
KR (1) KR100440352B1 (ru)
CN (1) CN1131236C (ru)
AT (1) ATE198600T1 (ru)
AU (1) AU709171B2 (ru)
CA (1) CA2246520C (ru)
DE (1) DE69611548T2 (ru)
DK (1) DK0885240T3 (ru)
EA (1) EA000789B1 (ru)
ES (1) ES2153996T3 (ru)
GR (1) GR3035208T3 (ru)
HK (1) HK1018276A1 (ru)
HU (1) HU226936B1 (ru)
IL (1) IL125414A (ru)
NO (1) NO311029B1 (ru)
NZ (1) NZ324300A (ru)
PT (1) PT885240E (ru)
WO (1) WO1997030068A1 (ru)
ZA (1) ZA971214B (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006028817A1 (de) * 2006-06-21 2007-12-27 Evonik Degussa Gmbh Aufarbeitung von Reaktionslösungen aus Ganzzell-Biotransformationen

Also Published As

Publication number Publication date
JP2000511878A (ja) 2000-09-12
ZA971214B (en) 1997-11-19
HK1018276A1 (en) 1999-12-17
AU709171B2 (en) 1999-08-26
JP4076098B2 (ja) 2008-04-16
DE69611548D1 (de) 2001-02-15
ES2153996T3 (es) 2001-03-16
PT885240E (pt) 2001-04-30
HUP9904410A2 (hu) 2000-05-28
CN1131236C (zh) 2003-12-17
NZ324300A (en) 1999-02-25
KR19990082445A (ko) 1999-11-25
ATE198600T1 (de) 2001-01-15
AU1175897A (en) 1997-09-02
NO983665L (no) 1998-08-11
KR100440352B1 (ko) 2004-09-18
HU226936B1 (en) 2010-03-29
WO1997030068A1 (en) 1997-08-21
CN1209137A (zh) 1999-02-24
CA2246520C (en) 2004-03-02
DE69611548T2 (de) 2001-06-07
NO983665D0 (no) 1998-08-11
CA2246520A1 (en) 1997-08-21
IL125414A0 (en) 1999-03-12
HUP9904410A3 (en) 2002-05-28
IL125414A (en) 2003-10-31
EP0885240A1 (en) 1998-12-23
EP0885240B1 (en) 2001-01-10
DK0885240T3 (da) 2001-01-29
GR3035208T3 (en) 2001-04-30
US6228851B1 (en) 2001-05-08
NO311029B1 (no) 2001-10-01
EA000789B1 (ru) 2000-04-24

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

PC4A Registration of transfer of a eurasian patent by assignment
PD4A Registration of transfer of a eurasian patent in accordance with the succession in title
MK4A Patent expired

Designated state(s): RU