EA199700265A1 - Добавочный протеин рецептора интерлейкина-1 человека - Google Patents

Добавочный протеин рецептора интерлейкина-1 человека

Info

Publication number
EA199700265A1
EA199700265A1 EA199700265A EA199700265A EA199700265A1 EA 199700265 A1 EA199700265 A1 EA 199700265A1 EA 199700265 A EA199700265 A EA 199700265A EA 199700265 A EA199700265 A EA 199700265A EA 199700265 A1 EA199700265 A1 EA 199700265A1
Authority
EA
Eurasian Patent Office
Prior art keywords
receptor
additional
human interleukin
additional protein
receptor protein
Prior art date
Application number
EA199700265A
Other languages
English (en)
Russian (ru)
Inventor
Ричард Энтони Чиззоните
Грейс Вонг Джу
Original Assignee
Ф.Хоффманн-Ля Рош Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ф.Хоффманн-Ля Рош Аг filed Critical Ф.Хоффманн-Ля Рош Аг
Publication of EA199700265A1 publication Critical patent/EA199700265A1/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EA199700265A 1995-01-23 1996-01-17 Добавочный протеин рецептора интерлейкина-1 человека EA199700265A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37626895A 1995-01-23 1995-01-23
PCT/EP1996/000181 WO1996023067A1 (fr) 1995-01-23 1996-01-17 Proteine accessoire humaine du recepteur de l'interleukine-1

Publications (1)

Publication Number Publication Date
EA199700265A1 true EA199700265A1 (ru) 1998-04-30

Family

ID=23484321

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199700265A EA199700265A1 (ru) 1995-01-23 1996-01-17 Добавочный протеин рецептора интерлейкина-1 человека

Country Status (19)

Country Link
EP (1) EP0808365A1 (fr)
JP (1) JPH10512453A (fr)
AR (1) AR003919A1 (fr)
AU (1) AU4537096A (fr)
BR (1) BR9606837A (fr)
CA (1) CA2210724A1 (fr)
CO (1) CO4480033A1 (fr)
CZ (1) CZ208197A3 (fr)
EA (1) EA199700265A1 (fr)
FI (1) FI973089A (fr)
HU (1) HUP9702458A2 (fr)
IL (1) IL116796A0 (fr)
MX (1) MX9705501A (fr)
NO (1) NO973404D0 (fr)
PE (1) PE64396A1 (fr)
PL (1) PL321538A1 (fr)
TR (1) TR199700652T1 (fr)
WO (1) WO1996023067A1 (fr)
ZA (1) ZA96333B (fr)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7011696A (en) * 1996-08-26 1998-03-19 Human Genome Sciences, Inc. Soluble interleukin-1 receptor accessory molecule
US6974682B1 (en) 1996-08-26 2005-12-13 Human Genome Sciences, Inc. Soluble interleukin-1 receptor accessory molecule
DE69738948D1 (de) 1996-12-06 2008-10-09 Amgen Inc Il-1-inhibitor in kombinationstherapie zur behandlung il-1-vermittelter krankheiten
US6294170B1 (en) 1997-08-08 2001-09-25 Amgen Inc. Composition and method for treating inflammatory diseases
EP0979282A1 (fr) * 1997-04-30 2000-02-16 F. Hoffmann-La Roche Ag Chemokine st38.2 du rat
US6280955B1 (en) * 1997-12-16 2001-08-28 Tularik Inc. Interleukin-1 receptor accessory proteins, nucleic acids and methods
AU755391B2 (en) 1997-12-23 2002-12-12 Immunex Corporation SIGIRR DNA and polypeptides
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
WO2002064630A2 (fr) * 2000-10-31 2002-08-22 Immunex Corporation Proteine accessoire de recepteur de l'il-1
GB2375604A (en) * 2001-05-18 2002-11-20 Warner Lambert Co Methods for screening using interleukin soluble trimolecular complex
CN1547486A (zh) 2001-06-26 2004-11-17 抗opgl抗体
KR100453877B1 (ko) 2001-07-26 2004-10-20 메덱스젠 주식회사 연쇄체화에 의한 면역 글로블린 융합 단백질의 제조 방법 및 이 방법에 의해 제조된 TNFR/Fc 융합 단백질, 상기 단백질을 코딩하는 DNA, 상기 DNA를 포함하는벡터, 및 상기 벡터에 의한 형질전환체
EP1450837A4 (fr) * 2001-08-07 2006-01-04 Immunex Corp Recepteurs de l'interleukine-1 dans le traitement de maladies
EA018072B1 (ru) 2002-09-06 2013-05-30 Амджен Инк. Антитело к рецептору интерлейкина-1 типа 1 (il-1r1) и его применение
ES2694252T3 (es) 2004-04-02 2018-12-19 Swedish Orphan Biovitrum Ab (Publ) Métodos para reducir la agregación de IL-1ra
PL1751175T3 (pl) * 2004-05-05 2013-03-29 Valorisation Recherche Soc En Commandite Antagoniści receptora IL-1, kompozycje i sposoby leczenia
US8618054B2 (en) 2004-05-05 2013-12-31 Valorisation-Rechereche Société en Commandite Interleukin-1 receptor antagonists, compositions, and methods of treatment
WO2007004060A2 (fr) * 2005-05-05 2007-01-11 Valorisation Hsj, Societe En Commandite Modulateurs du recepteur de la cytokine et leurs utilisations
TW200736277A (en) 2005-11-14 2007-10-01 Amgen Inc RANKL antibody-PTH/PTHrP chimeric molecules
WO2009120903A2 (fr) * 2008-03-26 2009-10-01 Cellerant Therapeutics, Inc. Récepteurs de cytokine associés aux troubles prolifératifs hématologiques myélogènes et utilisations correspondantes
EP2196476A1 (fr) 2008-12-10 2010-06-16 Novartis Ag Formulation d'anticorps
GB2472856B (en) * 2009-08-21 2012-07-11 Cantargia Ab IL1-RAP modulators and uses thereof
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
KR101989134B1 (ko) 2011-01-19 2019-06-13 칸타르기아 아베 항―il1rap 항체 및 그의 인간 치료 용도
CA2837651A1 (fr) * 2011-06-21 2012-12-27 Oncofactor Corporation Compositions et methodes pour la therapie et le diagnostic du cancer
WO2013006490A2 (fr) 2011-07-01 2013-01-10 Cellerant Therapeutics, Inc. Anticorps se liant spécifiquement à tim3
GB201403875D0 (en) 2014-03-05 2014-04-16 Cantargia Ab Novel antibodies and uses thereof
GB201413913D0 (en) 2014-08-06 2014-09-17 Cantargia Ab Novel antibodies and uses thereof
WO2016183106A1 (fr) 2015-05-11 2016-11-17 Natera, Inc. Procédés et compositions pour la détermination de la ploïdie
CA2990305A1 (fr) 2015-06-26 2016-12-29 Mab Discovery Gmbh Anticorps monoclonaux anti-il-1racp
EP3241845A1 (fr) 2016-05-06 2017-11-08 MAB Discovery GmbH Anticorps anti-il-1r3 humanisés
WO2018022982A1 (fr) 2016-07-29 2018-02-01 Trustees Of Boston University L'hématopoïèse clonale associée à l'âge accélère le développement d'une maladie cardio-métabolique
EP3401332A1 (fr) 2017-05-08 2018-11-14 MAB Discovery GmbH Anticorps anti-il-1r3 destinés à être utilisés dans des conditions inflammatoires
WO2018237075A1 (fr) 2017-06-20 2018-12-27 The Medical College Of Wisconsin, Inc. Évaluation du risque de complication d'une greffe avec l'adn acellulaire total
TW202021618A (zh) 2018-08-17 2020-06-16 美商23與我有限公司 抗il1rap抗體及其使用方法
US11931674B2 (en) 2019-04-04 2024-03-19 Natera, Inc. Materials and methods for processing blood samples
WO2021236962A1 (fr) 2020-05-20 2021-11-25 The Medical College Of Wisconsin, Inc. Compositions et méthodes d'inhibition du syndrôme de libération des cytokines
CN114835799A (zh) * 2021-05-28 2022-08-02 百奥赛图江苏基因生物技术有限公司 Il1rap基因人源化非人动物的构建方法及应用

Also Published As

Publication number Publication date
CA2210724A1 (fr) 1996-08-01
TR199700652T1 (xx) 1998-02-21
FI973089A0 (fi) 1997-07-22
MX9705501A (es) 1997-10-31
CZ208197A3 (en) 1997-11-12
PE64396A1 (es) 1997-01-28
ZA96333B (en) 1996-07-23
PL321538A1 (en) 1997-12-08
WO1996023067A1 (fr) 1996-08-01
HUP9702458A2 (hu) 1998-04-28
AU4537096A (en) 1996-08-14
JPH10512453A (ja) 1998-12-02
IL116796A0 (en) 1996-05-14
EP0808365A1 (fr) 1997-11-26
NO973404L (no) 1997-07-23
BR9606837A (pt) 1998-05-26
AR003919A1 (es) 1998-09-30
CO4480033A1 (es) 1997-07-09
NO973404D0 (no) 1997-07-23
FI973089A (fi) 1997-07-22

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