EA036704B1 - Способ лечения неалкогольной жировой болезни печени и неалкогольного стеатогепатита - Google Patents

Способ лечения неалкогольной жировой болезни печени и неалкогольного стеатогепатита Download PDF

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Publication number
EA036704B1
EA036704B1 EA201692050A EA201692050A EA036704B1 EA 036704 B1 EA036704 B1 EA 036704B1 EA 201692050 A EA201692050 A EA 201692050A EA 201692050 A EA201692050 A EA 201692050A EA 036704 B1 EA036704 B1 EA 036704B1
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EA
Eurasian Patent Office
Prior art keywords
nash
nafld
mbx
treatment
alcoholic
Prior art date
Application number
EA201692050A
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English (en)
Russian (ru)
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EA201692050A1 (ru
Inventor
Брайан Робертс
Сюэянь Ванг
Юнь-Цзюн Чой
Дэвид Карпф
Роберт Мартин
Чарльз А. Макуэртер
Original Assignee
Саймабэй Терапьютикс, Инк.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53373532&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA036704(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Саймабэй Терапьютикс, Инк. filed Critical Саймабэй Терапьютикс, Инк.
Publication of EA201692050A1 publication Critical patent/EA201692050A1/ru
Publication of EA036704B1 publication Critical patent/EA036704B1/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EA201692050A 2014-04-11 2015-04-10 Способ лечения неалкогольной жировой болезни печени и неалкогольного стеатогепатита EA036704B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461978335P 2014-04-11 2014-04-11
PCT/US2015/025416 WO2015157697A1 (en) 2014-04-11 2015-04-10 Treatment of nafld and nash

Publications (2)

Publication Number Publication Date
EA201692050A1 EA201692050A1 (ru) 2017-01-30
EA036704B1 true EA036704B1 (ru) 2020-12-10

Family

ID=53373532

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201692050A EA036704B1 (ru) 2014-04-11 2015-04-10 Способ лечения неалкогольной жировой болезни печени и неалкогольного стеатогепатита

Country Status (27)

Country Link
US (7) US9381181B2 (https=)
EP (1) EP3129018B1 (https=)
JP (1) JP6865038B2 (https=)
KR (1) KR102374499B1 (https=)
CN (1) CN106163508A (https=)
AU (1) AU2015243239B2 (https=)
BR (1) BR112016023269A8 (https=)
CA (1) CA2944139C (https=)
CL (1) CL2016002517A1 (https=)
CY (1) CY1122602T1 (https=)
DK (1) DK3129018T3 (https=)
EA (1) EA036704B1 (https=)
ES (1) ES2764467T3 (https=)
HR (1) HRP20192299T1 (https=)
IL (1) IL248193B (https=)
LT (1) LT3129018T (https=)
MX (1) MX369921B (https=)
NZ (1) NZ724740A (https=)
PH (1) PH12016501978B1 (https=)
PL (1) PL3129018T3 (https=)
PT (1) PT3129018T (https=)
RS (1) RS59637B1 (https=)
SG (1) SG11201608077PA (https=)
SI (1) SI3129018T1 (https=)
SM (1) SMT202000019T1 (https=)
UA (1) UA121208C2 (https=)
WO (1) WO2015157697A1 (https=)

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US20160324812A1 (en) 2016-11-10
KR20160136451A (ko) 2016-11-29
ES2764467T3 (es) 2020-06-03
US9381181B2 (en) 2016-07-05
CL2016002517A1 (es) 2017-05-05
JP6865038B2 (ja) 2021-04-28
EP3129018A1 (en) 2017-02-15
MX2016013375A (es) 2017-02-15
US9962346B2 (en) 2018-05-08
CN106163508A (zh) 2016-11-23
DK3129018T3 (da) 2020-01-20
US20190142776A1 (en) 2019-05-16
US11179359B2 (en) 2021-11-23
LT3129018T (lt) 2020-01-10
US20200009092A1 (en) 2020-01-09
SG11201608077PA (en) 2016-10-28
EA201692050A1 (ru) 2017-01-30
BR112016023269A8 (pt) 2021-06-29
SI3129018T1 (sl) 2020-02-28
US10188620B2 (en) 2019-01-29
US10722483B2 (en) 2020-07-28
CY1122602T1 (el) 2021-03-12
US9616039B2 (en) 2017-04-11
PH12016501978B1 (en) 2023-07-12
US20180008566A1 (en) 2018-01-11
PT3129018T (pt) 2020-01-15
AU2015243239B2 (en) 2019-11-14
JP2017513836A (ja) 2017-06-01
US20150290154A1 (en) 2015-10-15
PL3129018T3 (pl) 2020-05-18
US20210038546A1 (en) 2021-02-11
US20180228752A1 (en) 2018-08-16
KR102374499B1 (ko) 2022-03-14
IL248193B (en) 2019-03-31
CA2944139A1 (en) 2015-10-15
AU2015243239A1 (en) 2016-10-20
RS59637B1 (sr) 2020-01-31
MX369921B (es) 2019-11-26
UA121208C2 (uk) 2020-04-27
EP3129018B1 (en) 2019-10-23
PH12016501978A1 (en) 2016-12-19
US10342770B2 (en) 2019-07-09
CA2944139C (en) 2020-11-03
SMT202000019T1 (it) 2020-03-13
WO2015157697A1 (en) 2015-10-15
NZ724740A (en) 2019-11-29
BR112016023269A2 (pt) 2017-08-15
HRP20192299T1 (hr) 2020-03-06

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