EA031190B1 - Фармацевтические составы ингибитора киназ семейства raf, способы их получения и способы их применения - Google Patents
Фармацевтические составы ингибитора киназ семейства raf, способы их получения и способы их применения Download PDFInfo
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- EA031190B1 EA031190B1 EA201691918A EA201691918A EA031190B1 EA 031190 B1 EA031190 B1 EA 031190B1 EA 201691918 A EA201691918 A EA 201691918A EA 201691918 A EA201691918 A EA 201691918A EA 031190 B1 EA031190 B1 EA 031190B1
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Landscapes
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| PCT/US2015/022792 WO2015148828A1 (en) | 2014-03-26 | 2015-03-26 | Pharmaceutical formulations of a pan-raf kinase inhibitor, processes for their preparation, and methods of use |
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| ES2827024T3 (es) * | 2014-12-23 | 2021-05-19 | Dot Therapeutics 1 Inc | Combinación de inhibidores de Raf y de taxanos |
| WO2017066664A1 (en) * | 2015-10-16 | 2017-04-20 | Millennium Pharmaceuticals, Inc. | Combination therapy including a raf inhibitor for the treatment of colorectal cancer |
| TW201735949A (zh) | 2016-03-24 | 2017-10-16 | 千禧製藥公司 | 治療抗ctla4及抗pd-1組合治療中的胃腸道免疫相關不良事件之方法 |
| WO2017165491A1 (en) * | 2016-03-24 | 2017-09-28 | Millennium Pharmaceuticals, Inc. | Use of a pd-1 antagonist and a raf inhibitor in the treatment of cancer |
| US11760803B2 (en) | 2016-03-24 | 2023-09-19 | Takeda Pharmaceutical Company Limited | Methods of treating gastrointestinal immune-related adverse events in immune oncology treatments |
| US12122787B2 (en) | 2019-09-20 | 2024-10-22 | Shanghai Jemincare Pharmaceuticals Co., Ltd | Fused pyridone compound, and preparation method therefor and use thereof |
| EP4065122A4 (en) * | 2019-11-27 | 2023-12-27 | Day One Biopharmaceuticals, Inc. | Solid dispersion of pan-raf kinase inhibitor |
| AU2021376286A1 (en) * | 2020-11-06 | 2023-06-22 | Dana-Farber Cancer Institute, Inc. | Raf inhibitor for treating low grade glioma |
| CN117042772A (zh) * | 2020-11-06 | 2023-11-10 | 首日生物制药公司 | 用于治疗低级别胶质瘤的raf抑制剂 |
| WO2022178244A1 (en) * | 2021-02-19 | 2022-08-25 | Day One Biopharmaceuticals, Inc. | Combination of raf inhibitor and mek inhibitor |
| WO2023049807A2 (en) * | 2021-09-22 | 2023-03-30 | Sirnaomics, Inc. | Improved methods for preparing nanoparticle compositions containing histidine-lysine copolymers |
Citations (2)
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| WO2009006389A2 (en) * | 2007-06-29 | 2009-01-08 | Sunesis Pharmaceuticals, Inc. | Pyrimidine derivatives useful as raf kinase inhibitors |
| WO2013144923A1 (en) * | 2012-03-30 | 2013-10-03 | Takeda Pharmaceutical Company Limited | Administration of a raf inhibitor and a mek inhibitor in the treatment of melanoma |
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| US4843155A (en) | 1987-11-19 | 1989-06-27 | Piotr Chomczynski | Product and process for isolating RNA |
| US5346994A (en) | 1992-01-28 | 1994-09-13 | Piotr Chomczynski | Shelf-stable product and process for isolating RNA, DNA and proteins |
| DE19509807A1 (de) * | 1995-03-21 | 1996-09-26 | Basf Ag | Verfahren zur Herstellung von Wirkstoffzubereitungen in Form einer festen Lösung des Wirkstoffs in einer Polymermatrix sowie mit diesem Verfahren hergestellte Wirkstoffzubereitungen |
| US20050220865A1 (en) | 2004-04-02 | 2005-10-06 | Koleng John J | Compressed composition comprising magnesium salt |
| ZA200806138B (en) | 2005-12-16 | 2009-11-25 | Hanmi Pharm Ind Co Ltd | Solid dispersion comprising an active ingredient having a low melting point and tablet for oral administration comprising same |
| KR100767349B1 (ko) * | 2006-08-01 | 2007-10-17 | 삼천당제약주식회사 | 페노피브레이트를 함유하는 경구용 약제 조성물 및 그의제조방법 |
| EP2079450A2 (en) | 2006-11-08 | 2009-07-22 | Novavax, INC. | Method of preparing solid dosage forms of multi-phasic pharmaceutical compositions |
| JPWO2008114859A1 (ja) * | 2007-03-22 | 2010-07-08 | アステラス製薬株式会社 | ピラゾール誘導体を含有する医薬組成物 |
| NZ592194A (en) | 2008-09-17 | 2013-04-26 | Mylan Inc | Reversed wet granulation process for preparing granulates and pharmaceutical products containing them |
| US20130172375A1 (en) * | 2011-12-13 | 2013-07-04 | Hoffmann-La Roche Inc. | Pharmaceutical composition |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009006389A2 (en) * | 2007-06-29 | 2009-01-08 | Sunesis Pharmaceuticals, Inc. | Pyrimidine derivatives useful as raf kinase inhibitors |
| WO2013144923A1 (en) * | 2012-03-30 | 2013-10-03 | Takeda Pharmaceutical Company Limited | Administration of a raf inhibitor and a mek inhibitor in the treatment of melanoma |
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| Publication number | Publication date |
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| CR20160483A (es) | 2017-04-27 |
| JP2017511313A (ja) | 2017-04-20 |
| CN106456787A (zh) | 2017-02-22 |
| BR112016022219B1 (pt) | 2022-09-27 |
| JP6571105B2 (ja) | 2019-09-04 |
| EP3122334B1 (en) | 2019-06-26 |
| UY36046A (es) | 2015-10-30 |
| PE20170773A1 (es) | 2017-07-04 |
| GEP20186932B (en) | 2018-12-10 |
| DOP2016000254A (es) | 2017-02-15 |
| ECSP16084317A (es) | 2018-05-31 |
| US10426782B2 (en) | 2019-10-01 |
| MA39765A (fr) | 2017-02-01 |
| CO2016003340A2 (es) | 2017-02-17 |
| CA2943808A1 (en) | 2015-10-01 |
| EP3122334A1 (en) | 2017-02-01 |
| CA2943808C (en) | 2022-08-16 |
| US20170173033A1 (en) | 2017-06-22 |
| WO2015148828A1 (en) | 2015-10-01 |
| BR112016022219A2 (pt) | 2018-07-10 |
| EA201691918A1 (ru) | 2017-02-28 |
| ES2744298T3 (es) | 2020-02-24 |
| CN106456787B (zh) | 2020-12-18 |
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