EA030796B1 - Применение связывающих семафорин-4d молекул для промотирования нейрогенеза после инсульта - Google Patents
Применение связывающих семафорин-4d молекул для промотирования нейрогенеза после инсульта Download PDFInfo
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- EA030796B1 EA030796B1 EA201492067A EA201492067A EA030796B1 EA 030796 B1 EA030796 B1 EA 030796B1 EA 201492067 A EA201492067 A EA 201492067A EA 201492067 A EA201492067 A EA 201492067A EA 030796 B1 EA030796 B1 EA 030796B1
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- A—HUMAN NECESSITIES
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Landscapes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
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| US201261646119P | 2012-05-11 | 2012-05-11 | |
| US13/842,523 US10494440B2 (en) | 2012-05-11 | 2013-03-15 | Use of semaphorin-4D binding molecules to promote neurogenesis following stroke |
| PCT/US2013/040661 WO2013170221A1 (en) | 2012-05-11 | 2013-05-10 | Use of semaphorin-4d binding molecules to promote neurogenesis following stroke |
Publications (2)
| Publication Number | Publication Date |
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| EA201492067A1 EA201492067A1 (ru) | 2015-05-29 |
| EA030796B1 true EA030796B1 (ru) | 2018-09-28 |
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| CA (1) | CA2872928C (enExample) |
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| ES (1) | ES2882881T3 (enExample) |
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| MX (1) | MX358991B (enExample) |
| NZ (1) | NZ630864A (enExample) |
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| SG (1) | SG11201407416XA (enExample) |
| WO (1) | WO2013170221A1 (enExample) |
| ZA (1) | ZA201501674B (enExample) |
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| NO2427212T3 (enExample) | 2009-05-08 | 2018-01-20 | ||
| CN104168956A (zh) | 2011-10-11 | 2014-11-26 | 瓦西尼斯公司 | 臂板蛋白-4d结合分子用于调节血脑屏障渗透性的用途 |
| US9090709B2 (en) | 2012-03-28 | 2015-07-28 | Vaccinex, Inc. | Anti-SEMA4D antibodies and epitopes |
| US9708601B2 (en) | 2012-04-26 | 2017-07-18 | Vaccinex, Inc. | Fusion proteins to facilitate selection of cells infected with specific immunoglobulin gene recombinant vaccinia virus |
| US10494440B2 (en) | 2012-05-11 | 2019-12-03 | Vaccinex, Inc. | Use of semaphorin-4D binding molecules to promote neurogenesis following stroke |
| BR112015032690B1 (pt) | 2013-06-25 | 2020-03-10 | Vaccinex, Inc. | Uso de moléculas inibidoras de semaforina-4d em combinação com uma terapia imunomoduladora para inibir o crescimento tumoral e metástase |
| NZ630881A (en) | 2013-10-10 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treatment of atherosclerosis |
| NZ630892A (en) | 2013-10-21 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treating neurodegenerative disorders |
| BR112018071686A2 (pt) | 2016-04-22 | 2019-02-19 | Vaccinex, Inc. | exibição de proteínas integrais de membrana em vírions extracelulares envelopados de poxvírus |
| WO2018026715A1 (en) | 2016-08-02 | 2018-02-08 | Vaccinex, Inc. | Improved methods for producing polynucleotide libraries in vaccinia virus/eukaryotic cells |
| WO2018156509A1 (en) * | 2017-02-22 | 2018-08-30 | Vaccinex, Inc. | Early detection of glial cell activation in neurodegenerative or neuroinflammatory diseases |
| CN110636858B (zh) | 2017-05-05 | 2024-03-19 | 瓦西尼斯公司 | 人抗脑信号蛋白4d抗体 |
| WO2024182357A1 (en) * | 2023-02-28 | 2024-09-06 | Brandeis University | Compositions and methods for the chronic treatment of epilepsy and epileptogenesis |
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| US20070098707A1 (en) * | 2003-12-11 | 2007-05-03 | Genentech, Inc. | Methods and Compositions for Inhibiting C-MET Dimerization and Activation |
| US20080219971A1 (en) * | 2007-02-14 | 2008-09-11 | Vaccinex, Inc. | Human anti-cd100 antibodies |
| US20100285036A1 (en) * | 2009-05-08 | 2010-11-11 | Vaccinex, Inc. | Anti-CD100 Neutralizing Antibodies and Methods of Using the Same |
| US20120027758A1 (en) * | 2003-01-31 | 2012-02-02 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Use of anti-cd100 antibodies |
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| US10494440B2 (en) | 2012-05-11 | 2019-12-03 | Vaccinex, Inc. | Use of semaphorin-4D binding molecules to promote neurogenesis following stroke |
| BR112015032690B1 (pt) | 2013-06-25 | 2020-03-10 | Vaccinex, Inc. | Uso de moléculas inibidoras de semaforina-4d em combinação com uma terapia imunomoduladora para inibir o crescimento tumoral e metástase |
| NZ630881A (en) | 2013-10-10 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treatment of atherosclerosis |
| NZ630892A (en) | 2013-10-21 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treating neurodegenerative disorders |
| WO2018156509A1 (en) * | 2017-02-22 | 2018-08-30 | Vaccinex, Inc. | Early detection of glial cell activation in neurodegenerative or neuroinflammatory diseases |
-
2013
- 2013-03-15 US US13/842,523 patent/US10494440B2/en active Active
- 2013-05-10 BR BR112014028160-2A patent/BR112014028160B1/pt active IP Right Grant
- 2013-05-10 JP JP2015511789A patent/JP6218810B2/ja active Active
- 2013-05-10 MX MX2014013676A patent/MX358991B/es active IP Right Grant
- 2013-05-10 CN CN201910064594.5A patent/CN110064054A/zh active Pending
- 2013-05-10 EA EA201492067A patent/EA030796B1/ru not_active IP Right Cessation
- 2013-05-10 CA CA2872928A patent/CA2872928C/en active Active
- 2013-05-10 ES ES13787931T patent/ES2882881T3/es active Active
- 2013-05-10 AU AU2013259192A patent/AU2013259192B2/en not_active Ceased
- 2013-05-10 WO PCT/US2013/040661 patent/WO2013170221A1/en not_active Ceased
- 2013-05-10 DK DK13787931.8T patent/DK2846831T3/da active
- 2013-05-10 PT PT137879318T patent/PT2846831T/pt unknown
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- 2013-05-10 NZ NZ630864A patent/NZ630864A/en not_active IP Right Cessation
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2014
- 2014-11-10 IL IL235603A patent/IL235603B/en active IP Right Grant
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2015
- 2015-03-11 ZA ZA2015/01674A patent/ZA201501674B/en unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6635742B1 (en) * | 2000-01-25 | 2003-10-21 | Nuvelo, Inc. | Antibodies specific for semaphorin-like polypeptides |
| US20120027758A1 (en) * | 2003-01-31 | 2012-02-02 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Use of anti-cd100 antibodies |
| US20070098707A1 (en) * | 2003-12-11 | 2007-05-03 | Genentech, Inc. | Methods and Compositions for Inhibiting C-MET Dimerization and Activation |
| US20080219971A1 (en) * | 2007-02-14 | 2008-09-11 | Vaccinex, Inc. | Human anti-cd100 antibodies |
| US20100285036A1 (en) * | 2009-05-08 | 2010-11-11 | Vaccinex, Inc. | Anti-CD100 Neutralizing Antibodies and Methods of Using the Same |
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| SG11201407416XA (en) | 2015-03-30 |
| CN110064054A (zh) | 2019-07-30 |
| KR20150018555A (ko) | 2015-02-23 |
| CA2872928C (en) | 2021-02-16 |
| BR112014028160B1 (pt) | 2021-01-12 |
| KR102105436B1 (ko) | 2020-04-29 |
| EA201492067A1 (ru) | 2015-05-29 |
| JP2015517502A (ja) | 2015-06-22 |
| ZA201501674B (en) | 2021-06-30 |
| DK2846831T3 (en) | 2021-10-11 |
| CN104619341A (zh) | 2015-05-13 |
| IL235603B (en) | 2020-01-30 |
| US10494440B2 (en) | 2019-12-03 |
| ES2882881T3 (es) | 2021-12-03 |
| AU2013259192A1 (en) | 2014-11-27 |
| MX358991B (es) | 2018-08-31 |
| EP2846831A4 (en) | 2015-11-18 |
| IL235603A0 (en) | 2015-01-29 |
| EP2846831A1 (en) | 2015-03-18 |
| NZ630864A (en) | 2017-03-31 |
| EP2846831B1 (en) | 2021-07-07 |
| MX2014013676A (es) | 2015-02-05 |
| AU2013259192B2 (en) | 2018-02-22 |
| PT2846831T (pt) | 2021-08-19 |
| US20130302320A1 (en) | 2013-11-14 |
| WO2013170221A1 (en) | 2013-11-14 |
| CA2872928A1 (en) | 2013-11-14 |
| JP6218810B2 (ja) | 2017-10-25 |
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