EA021636B1 - Трансформанты talaromyces - Google Patents

Трансформанты talaromyces Download PDF

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Publication number
EA021636B1
EA021636B1 EA201200688A EA201200688A EA021636B1 EA 021636 B1 EA021636 B1 EA 021636B1 EA 201200688 A EA201200688 A EA 201200688A EA 201200688 A EA201200688 A EA 201200688A EA 021636 B1 EA021636 B1 EA 021636B1
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EA
Eurasian Patent Office
Prior art keywords
rgo
azp
azr
zeg
tng
Prior art date
Application number
EA201200688A
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English (en)
Russian (ru)
Other versions
EA201200688A1 (ru
Inventor
Алрик Питер Лос
Бренда Вонк
Марко Александер Берг Ван Ден
Роббертус Антониус Дамвельд
Корнелис Мария Якобус Сагт
Адрианус Вильхельмус Херманус Фоллебрехт
Маргот Элизабет Франсуаз Схоневелд-Бергманс
Original Assignee
ДСМ АйПи АССЕТС Б.В.
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Publication date
Application filed by ДСМ АйПи АССЕТС Б.В. filed Critical ДСМ АйПи АССЕТС Б.В.
Publication of EA201200688A1 publication Critical patent/EA201200688A1/ru
Publication of EA021636B1 publication Critical patent/EA021636B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2445—Beta-glucosidase (3.2.1.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2477—Hemicellulases not provided in a preceding group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01004—Cellulase (3.2.1.4), i.e. endo-1,4-beta-glucanase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01021—Beta-glucosidase (3.2.1.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01091—Cellulose 1,4-beta-cellobiosidase (3.2.1.91)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
EA201200688A 2009-11-04 2010-11-04 Трансформанты talaromyces EA021636B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09174990 2009-11-04
PCT/EP2010/066796 WO2011054899A1 (en) 2009-11-04 2010-11-04 Talaromyces transformants

Publications (2)

Publication Number Publication Date
EA201200688A1 EA201200688A1 (ru) 2012-12-28
EA021636B1 true EA021636B1 (ru) 2015-07-30

Family

ID=43297609

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201200688A EA021636B1 (ru) 2009-11-04 2010-11-04 Трансформанты talaromyces

Country Status (10)

Country Link
US (1) US8802415B2 (enExample)
EP (2) EP2496686A1 (enExample)
CN (1) CN102597213A (enExample)
AU (1) AU2010317063B2 (enExample)
BR (1) BR112012011596B1 (enExample)
CA (1) CA2779796A1 (enExample)
EA (1) EA021636B1 (enExample)
IN (1) IN2012DN03186A (enExample)
MX (1) MX2012005271A (enExample)
WO (1) WO2011054899A1 (enExample)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011214327B2 (en) 2010-02-11 2014-09-18 Dsm Ip Assets B.V. Polypeptide having cellobiohydrolase activity and uses thereof
EA201201125A1 (ru) 2010-02-11 2013-03-29 ДСМ АйПи АССЕТС Б.В. Клетка-хозяин, способная продуцировать ферменты, пригодные для деградации лигноцеллюлозного материала
AU2011273685B2 (en) * 2010-06-29 2014-12-11 Dsm Ip Assets B.V. Polypeptide having swollenin activity and uses thereof
EP3318574B1 (en) * 2010-06-29 2021-04-21 DSM IP Assets B.V. Polypeptide having beta-glucosidase activity and uses thereof
CN103620028B (zh) 2011-01-26 2017-05-03 诺维信公司 具有纤维二糖水解酶活性的多肽和编码该多肽的多核苷酸
MX2013007720A (es) 2011-01-26 2013-08-09 Novozymes As Polipeptidos que tienen actividad celobiohidrolasa y polinucleotidos que codifican para los mismos.
WO2012123429A1 (en) 2011-03-11 2012-09-20 Dsm Ip Assets B.V. Vector-host system
DK3091073T4 (da) 2011-08-04 2023-06-06 Novozymes Inc Polypeptider med xylanaseaktivitet og polynukleotider, der koder for dem
WO2013071883A1 (en) * 2011-11-18 2013-05-23 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
US9708591B2 (en) * 2011-11-18 2017-07-18 Novozymes Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
CN104508114A (zh) * 2012-06-19 2015-04-08 帝斯曼知识产权资产管理有限公司 用于在细胞中表达基因的启动子
KR102134498B1 (ko) 2013-02-04 2020-07-16 디에스엠 아이피 어셋츠 비.브이. 탄수화물 분해 폴리펩티드 및 이의 용도
EP3457138A3 (en) 2013-04-30 2019-06-19 Université de Montréal Novel biomarkers for acute myeloid leukemia
DK2994529T3 (en) * 2013-05-10 2019-03-04 Novozymes As Polypeptides with xylanase activity and polynucleotides encoding them
WO2014202622A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202616A2 (en) * 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202624A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202620A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202621A1 (en) 2013-06-20 2014-12-24 Dsm Ip Assets B.V. Carbohydrate degrading polypeptide and uses thereof
BR112016002008B1 (pt) 2013-08-02 2021-06-22 Pfizer Inc. Anticorpos anti-cxcr4, seu uso, conjugado anticorpo-fármaco e composição farmacêutica
WO2015081139A1 (en) 2013-11-26 2015-06-04 Novozymes A/S Enzyme compositions and uses thereof
AU2015260215B2 (en) * 2014-05-15 2017-08-31 Ihi Corporation Liquid fuel production method using biomass
MY182924A (en) 2014-06-06 2021-02-05 Novozymes As Enzyme compositions and uses thereof
EP3242950B1 (en) 2015-01-06 2021-10-06 DSM IP Assets B.V. A crispr-cas system for a filamentous fungal host cell
SG10201912823PA (en) 2015-04-13 2020-02-27 Pfizer Therapeutic antibodies and their uses
US10913938B2 (en) 2016-07-29 2021-02-09 Dsm Ip Assets B.V. Polypeptides having cellulolytic enhancing activity and uses thereof
CN107022535B (zh) * 2017-04-24 2020-07-14 中国农业科学院饲料研究所 真菌来源的多结构域酸性纤维素酶及其基因和应用
WO2019059404A1 (ja) 2017-09-25 2019-03-28 味の素株式会社 タンパク質の製造法および二糖の製造法
EP3938525A1 (en) * 2019-03-12 2022-01-19 DSM IP Assets B.V. Process for producing a fermentation broth
CN110184196B (zh) * 2019-05-09 2023-04-21 慕恩（广州）生物科技有限公司 一种篮状菌及其应用
CN113046339B (zh) * 2019-12-27 2023-05-09 菲吉乐科(南京)生物科技有限公司 用于噬菌体发酵液后处理的过滤助剂及其制备方法和应用
JP2023533793A (ja) 2020-07-17 2023-08-04 ファイザー・インク 治療用抗体およびそれらの使用
CN113584001B (zh) * 2021-01-07 2024-05-28 北京化工大学 一种alpha-L-鼠李糖苷酶、其制备方法及应用
US20240218341A1 (en) 2021-04-06 2024-07-04 Dsm Ip Assets B.V. Enzyme composition
BR112023020357A2 (pt) 2021-04-06 2023-11-21 Dsm Ip Assets Bv Composição de enzima
WO2022214458A1 (en) 2021-04-06 2022-10-13 Dsm Ip Assets B.V. Enzyme composition
CN113717860B (zh) * 2021-07-07 2023-05-16 昆明理工大学 黄篮状菌在三七总皂苷转化为小极性人参皂苷中的应用
KR102695882B1 (ko) * 2021-11-30 2024-08-14 국립낙동강생물자원관 담수환경에서 분리된 폴리에틸렌 분해능을 가지는 탈라로마이세스 속 nnibrfg59 균주 및 이의 용도
CN113980823B (zh) * 2021-12-10 2022-10-14 中南大学 发菌科下一株新属菌株及其应用
CN114262715B (zh) * 2021-12-28 2023-07-28 中国环境科学研究院 一种堆肥产品中抗性基因环境健康风险评估的方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001070998A1 (en) * 2000-03-20 2001-09-27 Dsm N.V. Talaromyces emersonii beta-glucanases
WO2002024926A1 (en) * 2000-09-21 2002-03-28 Dsm N.V. Talaromyces xylanases
WO2007091231A1 (en) * 2006-02-10 2007-08-16 National University Of Ireland, Galway Talaromyces emersonii enzyme systems

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4288627A (en) 1980-02-12 1981-09-08 Phillips Petroleum Company Oxidation of thiols employing cobalt molybdate/triethylamine catalyst
ES2198410T3 (es) 1993-07-23 2004-02-01 Dsm Ip Assets B.V. Cepas recombinantes de hongos filamentosos libres de gen marcador de seleccion: un metodo para obtener dichas cepas y su utilizacion.
WO1997006261A2 (en) 1995-08-03 1997-02-20 Gist-Brocades B.V. THE USE OF HOMOLOGOUS amdS GENES AS SELECTABLE MARKERS
WO1998037179A2 (en) 1997-02-20 1998-08-27 Dsm N.V. Fermentative production of valuable compounds on an industrial scale using chemically defined media
ES2287989T3 (es) 1997-12-22 2007-12-16 Dsm Ip Assets B.V. Clonacion de expresion en hongos filamentosos.
US6058898A (en) 1998-12-28 2000-05-09 Detroit Diesel Corporation Structural oil pan with integrated oil filtration and cooling system
JP2000189757A (ja) 1998-12-30 2000-07-11 Volvo Ab 触媒式浄化デバイス
PL1733040T3 (pl) 2004-04-02 2011-01-31 Dsm Ip Assets Bv Mutanty grzybów nitkowatych o udoskonalonej wydajności rekombinacji homologicznej
CA2560205A1 (en) 2004-04-16 2005-10-27 Dsm Ip Assets B.V. Fungal promoters for expressing a gene in a fungal cell
US7202419B2 (en) 2004-07-20 2007-04-10 Dragonwave Inc. Multi-layer integrated RF/IF circuit board including a central non-conductive layer
CN101107354B (zh) 2005-01-24 2012-05-30 帝斯曼知识产权资产管理有限公司 用于在有丝真菌细胞中生产感兴趣化合物的方法
US20080227148A1 (en) 2005-03-01 2008-09-18 Thibaut Jose Wenzel Aspergillus Promotors for Expressing a Gene in a Fungal Cell
EP2004826B1 (en) 2006-04-08 2011-03-02 DSM IP Assets B.V. Improved method for homologous recombination in eukaryotic cells
WO2008053018A2 (en) 2006-11-02 2008-05-08 Dsm Ip Assets B.V. Improved production of secreted proteins by filamentous fungi
WO2008098933A1 (en) 2007-02-15 2008-08-21 Dsm Ip Assets B.V. A recombinant host cell for the production of a compound of interest

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001070998A1 (en) * 2000-03-20 2001-09-27 Dsm N.V. Talaromyces emersonii beta-glucanases
WO2002024926A1 (en) * 2000-09-21 2002-03-28 Dsm N.V. Talaromyces xylanases
WO2007091231A1 (en) * 2006-02-10 2007-08-16 National University Of Ireland, Galway Talaromyces emersonii enzyme systems

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
KARLSSON J. ET AL.: "Homologous expression and characterization of Cel61A (EG IV) of Trichoderma reesei", EUROPEAN JOURNAL OF BIOCHEMISTRY, BLACKWELL PUBLISHING, BERLIN, DE, vol. 268, no. 24, 1 December 2001 (2001-12-01), pages 6498-6507, XP002269955, ISSN: 0014-2956, DOI: DOI:10.1046/J.0014-2956.2001.02605.X, page 6504, column 2 *
MURRAY F.R. ET AL.: "Isolation of the glucose oxidase gene from Talaromyces flavus and characterisation of its role in the biocontrol of VerticiIlium dahliae", CURRENT GENETICS, NEW YORK, NY, US, vol. 32, no. 5, 1 November 1997 (1997-11-01), pages 367-375, XP002558854, ISSN: 0172-8083, DOI: DOI:10.1007/S002940050290 cited in the application page 370, column 2 *
MURRAY P. ET AL.: "Expression in Trichoderma reesei and characterisation of a thermostable family 3 beta-giucosidase from the moderately thermophilic fungus Talaromyces emersonii", PROTEIN EXPRESSION AND PURIFICATION, ACADEMIC PRESS, SAN DIEGO, CA, vol. 38, no. 2, 1 December 2004 (2004-12-01), pages 248-257, XP004649879, ISSN: 1046-5928, DOI: DOI:10.1016/J.PEP.2004.08.006, page 249, column 1, page 255 *

Also Published As

Publication number Publication date
MX2012005271A (es) 2012-06-28
AU2010317063B2 (en) 2014-10-23
BR112012011596B1 (pt) 2018-10-02
US8802415B2 (en) 2014-08-12
EP2496686A1 (en) 2012-09-12
IN2012DN03186A (enExample) 2015-09-25
EP2955221A1 (en) 2015-12-16
EA201200688A1 (ru) 2012-12-28
CA2779796A1 (en) 2011-05-12
BR112012011596A2 (pt) 2016-05-31
AU2010317063A1 (en) 2012-05-24
US20120276567A1 (en) 2012-11-01
WO2011054899A1 (en) 2011-05-12
CN102597213A (zh) 2012-07-18

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