WO2014202616A2 - Rasamsonia gene and use thereof - Google Patents

Rasamsonia gene and use thereof Download PDF

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Publication number
WO2014202616A2
WO2014202616A2 PCT/EP2014/062737 EP2014062737W WO2014202616A2 WO 2014202616 A2 WO2014202616 A2 WO 2014202616A2 EP 2014062737 W EP2014062737 W EP 2014062737W WO 2014202616 A2 WO2014202616 A2 WO 2014202616A2
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Prior art keywords
protein
putative
uncharacterized
uncharacterized protein
hypothetical
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PCT/EP2014/062737
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French (fr)
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WO2014202616A3 (en
Inventor
Liang Wu
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Dsm Ip Assets B.V.
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Publication of WO2014202616A2 publication Critical patent/WO2014202616A2/en
Publication of WO2014202616A3 publication Critical patent/WO2014202616A3/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi

Definitions

  • the present invention relates to DNA of Rasamsonia emersonii.
  • This DNA contains nucleotide sequences such as genes, regulatory elements and other nucleotide sequences.
  • the present invention also relates to polypeptides having biological activity and comprising an amino acid sequence encoded by a nucleotide sequence.
  • the present invention relates to DNA of Rasamsonia emersonii.
  • This DNA contains genes, regulatory elements and other nucleotide sequences.
  • This DNA may encode useful biologically active substances such as enzymes. These enzymes may be used in several industrial applications. Enzymes are for example used in the chemical industry and other industrial applications when specific catalysts are required, for example in the food or feed, textile, pulp or paper or detergent industries and other industries. Enzymes in general are limited in the number of reactions they have evolved to catalyze and their deactivation at high temperatures. As a consequence, protein engineering is an active area of research and involves attempts to create new enzymes with novel properties, either through rational design or in vitro evolution. These efforts have begun to be successful, and a few enzymes have now been designed to improve enzymatic reactions. For designing it is essential to have starting sequences from useful microorganisms especially thermophilic microorganisms like fungi.
  • the present invention provides a polypeptide which comprises
  • variant polypeptide has at least 70% sequence identity with the sequence set out in SEQ ID NO: 20501 to 32240, or (ii) has an amino acid sequence that differs in 1 , 2, 3, 4, 5, 6, 7, 8, 9, 10, 1 1 or 12 amino acids from the amino acid sequence of SEQ ID NO: 20501 to 32240.
  • the polypeptide of the invention has biological activity, preferably is a polypeptide such as an enzyme, more preferably is an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase or is capable to alter or influence the expression of an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase and most preferably is a carbohydrate degrading enzyme and/or carbohydrate hydrolysing enzyme, preferably has an activity mentioned in Table 1 .
  • the present invention provides a polynucleotide having a nucleic acid sequence whereby the nucleic acid sequence is selected from the group consisting of:
  • nucleic acid sequence encoding (i) the amino acid sequence of SEQ ID NO: 20501 to 32240, (ii) an amino acid sequence having at least 70% identity with the amino acid sequence of SEQ I D NO: 20501 to 32240, or (iii) an amino acid sequence that differs in 1 , 2, 3, 4, 5, 6, 7, 8, 9, 10, 1 1 or 12 amino acids from the amino acid sequence of SEQ ID NO: 20501 to 32240; or
  • the polynucleotide of the invention has a nucleic acid sequence coding for a polypeptide which has biological activity
  • the polypeptide is a polypeptide such as an enzyme, more preferably is an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase or is capable to alter or influence the expression of an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase and most preferably is a carbohydrate degrading enzyme and/or carbohydrate hydrolysing enzyme, preferably has an activity mentioned in Table 1 .
  • the invention also provides a nucleic acid construct or vector comprising the polynucleotide of the invention and a cell comprising the polynucleotide of the invention or a nucleic acid construct or vector of the invention.
  • the invention further provides a cell wherein the polynucleotide according to the invention is mutated or deleted from the genome to obtain lower or no activity of the polypeptide or lower or no expression of the polypeptide encoded by said polynucleotide compared to the cell wherein the polynucleotide of the invention is not mutated or deleted from the genome.
  • the invention further provides a mutant or recombinant cell wherein the polynucleotide according to the invention is lower or not expressed compared to the native or starting cell. Lower expression can be obtained for example by altering or deleting the promoter.
  • the invention further provides a mutant or recombinant cell wherein the polynucleotide according to the invention is overexpressed compared to the native or starting cell.
  • Overexpression can be obtained for example by altering the promoter or by introducing one or more copies of polynucleotide according to the invention in the cell.
  • the cell of the invention is a fungal cell, preferably a fungal cell selected from the group consisting of the genera Acremonium, Agaricus, Aspergillus, Aureobasidium, Chrysosporium, Coprinus, Cryptococcus, Filibasidium, Fusarium, Humicola, Magnaporthe, Mucor, Myceliophthora, Neocallimastix, Neurospora, Paecilomyces, Penicillium, Piromyces, Panerochaete, Pleurotus, Schizophyllum, Talaromyces, Rasamsonia, Saccharomyces, Thermoascus, Thielavia, Tolypocladium, and Trichoderma.
  • the cell of the invention is a recombinant cell.
  • one or more gene can be deleted, knocked-out or disrupted in full or in part, wherein optionally the gene encodes for a protease.
  • the invention also provides a method for the preparation of a polypeptide according to the invention having preferably biological activity, which method comprises cultivating a cell of the invention under conditions which allow for expression of said polypeptide and, optionally, recovering the expressed polypeptide.
  • the invention also provides a method of producing an enzyme or enzyme composition comprising the fermentation of the cell according of the invention and optionally recovery of the enzyme or enzyme composition
  • the invention provides a composition
  • a composition comprising: (i) the polypeptide of the invention and; (ii) a cellulase and/or a hemicellulase and/or a pectinase, preferably the cellulase is a GH61 , cellobiohydrolase, cellobiohydrolase I, cellobiohydrolase II, endo- ⁇ -1 ,4-glucanase, ⁇ -glucosidase or ⁇ -(1 ,3)(1 ,4)-glucanase and/or the hemicellulase is an endoxylanase, ⁇ -xylosidase, oL-arabinofuranosidase, oD-glucuronidase feruloyl esterase, coumaroyl esterase, a-galactosidase, ⁇ -galactosidase, ⁇ -mannanase or ⁇ - mannosidas
  • Another aspect of the invention relates to the use of a polypeptide of the invention and/or a composition of the invention to produce sugar from a lignocellulosic material.
  • the invention also provides:
  • a method for the preparation of a polypeptide having preferably biological activity comprises cultivating a cell of the invention under conditions which allow for expression of said polypeptide and, optionally, recovering the expressed polypeptide;
  • composition comprising: (i) a polypeptide of the invention and; (ii) a cellulase and/or a hemicellulase and/or a pectinase.
  • polypeptides of the invention may have all kinds of use.
  • the polypeptides of the invention having carbohydrate degrading and/or carbohydrate hydrolysing activity may be used in industrial processes.
  • the invention provides a method for the treatment of a substrate comprising carbohydrate material which method comprises contacting the substrate with a polypeptide or a composition of the invention.
  • a method for producing a sugar or sugars from lignocellulosic material comprises contacting the lignocellulosic material with a polypeptide or a composition of the invention.
  • the invention provides a method for producing a fermentation product, which method comprises: producing a fermentable sugar using the described above; and fermenting the resulting fermentable sugar, thereby to produce a fermentation product.
  • a polypeptide or a composition of the invention may also be used, for example, in the preparation of a food product, in the preparation of a detergent, in the preparation of an animal feed, in the treatment of pulp or in the manufacture of a paper or in the preparation of a fabric or textile or in the cleaning thereof.
  • the invention also provides: a processed material obtainable by contacting a plant material or lignocellulosic material with a polypeptide or a composition of the invention;
  • a food or feed comprising a polypeptide or a composition of the invention; and a plant or a part thereof which comprises a polynucleotide, a polypeptide, a vector or a cell according to the invention.
  • the invention further provides a polynucleotide coding for a signal sequence having a sequence set out in SEQ ID NO: 32241 to 33730 or having a sequence that differs 1 , 2 or 3 amino acids from the sequence set out in SEQ ID NO: 32241 to 33730.
  • Fig 1 Map of pGBTOP for expression of genes in A. niger. Depicted are the gene of interest (GOI) expressed from the glucoamylase promoter (PglaA). In addition, the glucoamylase flank (3'glaA) of the expression cassette is depicted. In this application a gene of interest is the coding sequence of the protein or polypeptide of the invention as defined hereinafter.
  • Fig. 2 shows a schematic diagram of plasmid pEBA1006 that was used in bipartite gene-targeting method in combination with the pEBA expression vector containing the protein of the invention with the goal to replace the RePepA ORF and approximately 1500 nucleotides upstream of the start ATG codon by the expression cassette of the protein of the invention in Rasamsonia emersonii.
  • the vector comprises the 3' part of the ble coding region, the A.nidulans trpC terminator, a lox71 site, a 2500 bp 3' flanking region of the RePepA ORF, and the backbone of pUC19 (Invitrogen, Breda, The Netherlands).
  • the £. coli DNA was removed by digestion with restriction enzyme A/oil, prior to transformation of the R. emersonii strains.
  • Fig. 3 shows a schematic diagram of pEBA expression plasmid containing the protein of the invention that was used in bipartite gene-targeting method in combination with the pEBA1006 vector with the goal to replace the RePepA ORF and approximately 1500 nucleotides upstream of the start ATG codon by the expression cassette of the protein of the invention in Rasamsonia emersonii.
  • the vector comprises a 1500 bp 5' flanking region 1 .5 kb upstream of the RePepA ORF for targeting in the RePepA locus, the protein of the invention-expression cassette consisting of R.
  • emersonii promoter 2 the protein of the invention-coding region and the A.nidulans amdS terminator (TamdS), a lox66 site, the non-functional 5' part of the ble coding region (5' ble) driven by the A.nidulans gpdA promoter.
  • the E. coli DNA was removed by digestion with restriction enzyme A/oil, prior to transformation of the R. emersonii strains.
  • Fig. 4 shows the pEBADEL.1 vector.
  • Part of the vector fragment is used in bipartite gene-targeting method in combination with the pEBADEL2 vector with the goal to delete the ORF of the protein of the invention (GOI) in Rasamsonia emersonii.
  • the vector comprises a 1200 bp 5' upstream flanking region of the ORF encoding the protein of the invention and the 5' part of the ble coding region driven by the A.nidulans gpdA promoter and the backbone of pUC19 (Invitrogen, Breda, The Netherlands).
  • the E. coli DNA is removed by digestion with restriction enzyme Notl, prior to transformation of the R. emersonii strains.
  • Fig. 5 shows the pEBADEL.1 vector.
  • Part of the vector fragment is used in bipartite gene-targeting method in combination with the pEBADEL.1 vector with the goal to delete the ORF encoding the protein of the invention (GOI) in Rasamsonia emersonii.
  • the vector comprises the 3' part of the ble coding region, the A.nidulans trpC terminator, and a -1200 bp 3' flanking region downstream of the ORF encoding the protein of the invention, and the backbone of pUC19 (Invitrogen, Breda, The Netherlands).
  • the E. coli DNA is removed by digestion with restriction enzyme Notl, prior to transformation of the R. emersonii strains.
  • Fig. 6 shows the strategy used to delete the ORF gene encoding the protein of the invention in R. emersonii.
  • the deletion vectors comprise the overlapping non-functional ble selection marker fragments (split marker) flanked by loxP sites and 5' and 3' homologous regions of the gene encoding the protein of the invention (GOI) for targeting (1 ).
  • the constructs integrate through triple homologous recombination (X) at the locus of the gene of the invention and at the overlapping homologous non-functional ble selection marker fragment (2) and replaces the genomic gene copy (3).
  • Re01 .g01 190 hypothetical protein 1 16 10366 20616
  • Re01 .g01330 Putative uncharacterized protein 130 10380 20630
  • Beta-galactosidase EC 3.2.1.23 259 10509 20759 30788 32278
  • Re01.g02930 Putative uncharacterized protein 290 10540 20790
  • Re01.g02980 Putative uncharacterized protein 295 10545 20795
  • Beta-glucosidase EC 3.2.1.21
  • Re01.g03400 40S ribosomal protein S5 336 10586 20836 Re01.g03410 SDA1 domain protein 337 10587 20837
  • Re01.g03560 (AFlLorthologue AFUAJ G15240) 352 10602 20852
  • Re01.g04010 (AFU . orthologue AFUAJ G14380) 396 10646 20896
  • Re01.g04170 protein 1 putative 412 10662 20912
  • Re01.g04400 Remark: YS24 is part of the small 435 10685 20935
  • Pre-rRNA processing protein Tsr1 Pre-rRNA processing protein
  • Re01.g05320 protein putative 525 10775 21025
  • Protein transport protein (SEC31 ),
  • Lactoylglutathione lyase (Glo1 )
  • Re01.g06580 Putative uncharacterized protein 650 10900 21 150 30842 32332
  • Re01.g06590 Putative uncharacterized protein 651 10901 21 151 30843 32333
  • Re01.g07080 Putative uncharacterized protein 700 10950 21200
  • Hexokinase family protein XprF Hexokinase family protein XprF
  • Rab6 of H. sapiens is
  • Re01.g07680 Putative uncharacterized protein 759 1 1009 21259 30865 32355

Abstract

The invention relates to apolypeptide which comprises (a) an amino acid sequence set out in SEQ ID NO: 20501 to 32240; (b) an amino acid sequence encoded by the nucleic acid sequence of SEQ ID NO: 1 to 20500; (c) or a variant polypeptide, wherein the variant polypeptide (i) has at least 70% sequence identity with the sequence set out in SEQ ID NO: 20501 to 32240, or (ii) has an amino acid sequence that differs in, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12 amino acids from the amino acid sequence of SEQ ID NO: 20501 to 32240. The invention also relates to methods for using the polypeptide in industrial processes. 1 Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins.

Description

RASAMSONIA GENES AND USE THEREOF
Field of the invention
The present invention relates to DNA of Rasamsonia emersonii. This DNA contains nucleotide sequences such as genes, regulatory elements and other nucleotide sequences. The present invention also relates to polypeptides having biological activity and comprising an amino acid sequence encoded by a nucleotide sequence.
Background of the invention
The present invention relates to DNA of Rasamsonia emersonii. This DNA contains genes, regulatory elements and other nucleotide sequences. This DNA may encode useful biologically active substances such as enzymes. These enzymes may be used in several industrial applications. Enzymes are for example used in the chemical industry and other industrial applications when specific catalysts are required, for example in the food or feed, textile, pulp or paper or detergent industries and other industries. Enzymes in general are limited in the number of reactions they have evolved to catalyze and their deactivation at high temperatures. As a consequence, protein engineering is an active area of research and involves attempts to create new enzymes with novel properties, either through rational design or in vitro evolution. These efforts have begun to be successful, and a few enzymes have now been designed to improve enzymatic reactions. For designing it is essential to have starting sequences from useful microorganisms especially thermophilic microorganisms like fungi.
Summary of the invention
The present invention provides a polypeptide which comprises
(a) an amino acid sequence set out in SEQ ID NO: 20501 to 32240;
(b) an amino acid sequence encoded by the nucleic acid sequence of SEQ ID NO: 1 to 20500;
(c) or a variant polypeptide,
wherein the variant polypeptide (i) has at least 70% sequence identity with the sequence set out in SEQ ID NO: 20501 to 32240, or (ii) has an amino acid sequence that differs in 1 , 2, 3, 4, 5, 6, 7, 8, 9, 10, 1 1 or 12 amino acids from the amino acid sequence of SEQ ID NO: 20501 to 32240. Preferably the polypeptide of the invention has biological activity, preferably is a polypeptide such as an enzyme, more preferably is an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase or is capable to alter or influence the expression of an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase and most preferably is a carbohydrate degrading enzyme and/or carbohydrate hydrolysing enzyme, preferably has an activity mentioned in Table 1 .
Furthermore the present invention provides a polynucleotide having a nucleic acid sequence whereby the nucleic acid sequence is selected from the group consisting of:
(a) a nucleic acid sequence having at least 70% identity with the nucleic acid sequence of SEQ ID NO: 1 to 20500;
(b) a nucleic acid sequence hybridizing with the complement of the nucleic acid sequence of SEQ ID NO: 1 to 20500;
(c) a nucleic acid sequence encoding (i) the amino acid sequence of SEQ ID NO: 20501 to 32240, (ii) an amino acid sequence having at least 70% identity with the amino acid sequence of SEQ I D NO: 20501 to 32240, or (iii) an amino acid sequence that differs in 1 , 2, 3, 4, 5, 6, 7, 8, 9, 10, 1 1 or 12 amino acids from the amino acid sequence of SEQ ID NO: 20501 to 32240; or
(d) a nucleotide sequence which is the reverse complement of a nucleotide sequence as defined in (a), (b) or (c).
Preferably the polynucleotide of the invention has a nucleic acid sequence coding for a polypeptide which has biological activity, preferably the polypeptide is a polypeptide such as an enzyme, more preferably is an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase or is capable to alter or influence the expression of an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase and most preferably is a carbohydrate degrading enzyme and/or carbohydrate hydrolysing enzyme, preferably has an activity mentioned in Table 1 .
The invention also provides a nucleic acid construct or vector comprising the polynucleotide of the invention and a cell comprising the polynucleotide of the invention or a nucleic acid construct or vector of the invention.
The invention further provides a cell wherein the polynucleotide according to the invention is mutated or deleted from the genome to obtain lower or no activity of the polypeptide or lower or no expression of the polypeptide encoded by said polynucleotide compared to the cell wherein the polynucleotide of the invention is not mutated or deleted from the genome.
The invention further provides a mutant or recombinant cell wherein the polynucleotide according to the invention is lower or not expressed compared to the native or starting cell. Lower expression can be obtained for example by altering or deleting the promoter.
The invention further provides a mutant or recombinant cell wherein the polynucleotide according to the invention is overexpressed compared to the native or starting cell. Overexpression can be obtained for example by altering the promoter or by introducing one or more copies of polynucleotide according to the invention in the cell.
According to another aspect of the invention the cell of the invention is a fungal cell, preferably a fungal cell selected from the group consisting of the genera Acremonium, Agaricus, Aspergillus, Aureobasidium, Chrysosporium, Coprinus, Cryptococcus, Filibasidium, Fusarium, Humicola, Magnaporthe, Mucor, Myceliophthora, Neocallimastix, Neurospora, Paecilomyces, Penicillium, Piromyces, Panerochaete, Pleurotus, Schizophyllum, Talaromyces, Rasamsonia, Saccharomyces, Thermoascus, Thielavia, Tolypocladium, and Trichoderma. Preferably the cell of the invention is a recombinant cell.
In the cell of the invention one or more gene can be deleted, knocked-out or disrupted in full or in part, wherein optionally the gene encodes for a protease.
The invention also provides a method for the preparation of a polypeptide according to the invention having preferably biological activity, which method comprises cultivating a cell of the invention under conditions which allow for expression of said polypeptide and, optionally, recovering the expressed polypeptide.
The invention also provides a method of producing an enzyme or enzyme composition comprising the fermentation of the cell according of the invention and optionally recovery of the enzyme or enzyme composition
Furthermore the invention provides a composition comprising: (i) the polypeptide of the invention and; (ii) a cellulase and/or a hemicellulase and/or a pectinase, preferably the cellulase is a GH61 , cellobiohydrolase, cellobiohydrolase I, cellobiohydrolase II, endo-β-1 ,4-glucanase, β-glucosidase or β-(1 ,3)(1 ,4)-glucanase and/or the hemicellulase is an endoxylanase, β-xylosidase, oL-arabinofuranosidase, oD-glucuronidase feruloyl esterase, coumaroyl esterase, a-galactosidase, β-galactosidase, β-mannanase or β- mannosidase. Additionally the invention provides a method for the treatment of a substrate comprising cellulose and/or hemicellulose, optionally a plant material, which method comprises contacting the substrate with a polypeptide of the invention and/or a composition of the invention.
Another aspect of the invention relates to the use of a polypeptide of the invention and/or a composition of the invention to produce sugar from a lignocellulosic material.
The invention also provides:
a method for the preparation of a polypeptide having preferably biological activity, which method comprises cultivating a cell of the invention under conditions which allow for expression of said polypeptide and, optionally, recovering the expressed polypeptide;
a polypeptide obtainable by such a method; and
a composition comprising: (i) a polypeptide of the invention and; (ii) a cellulase and/or a hemicellulase and/or a pectinase.
The polypeptides of the invention may have all kinds of use. For example the polypeptides of the invention having carbohydrate degrading and/or carbohydrate hydrolysing activity may be used in industrial processes. Optionally, the invention provides a method for the treatment of a substrate comprising carbohydrate material which method comprises contacting the substrate with a polypeptide or a composition of the invention.
According to one aspect of the invention a method is provided for producing a sugar or sugars from lignocellulosic material which method comprises contacting the lignocellulosic material with a polypeptide or a composition of the invention.
Sugars produced in this way may be used in a fermentation process. Accordingly, the invention provides a method for producing a fermentation product, which method comprises: producing a fermentable sugar using the described above; and fermenting the resulting fermentable sugar, thereby to produce a fermentation product.
A polypeptide or a composition of the invention may also be used, for example, in the preparation of a food product, in the preparation of a detergent, in the preparation of an animal feed, in the treatment of pulp or in the manufacture of a paper or in the preparation of a fabric or textile or in the cleaning thereof.
The invention also provides: a processed material obtainable by contacting a plant material or lignocellulosic material with a polypeptide or a composition of the invention;
a food or feed comprising a polypeptide or a composition of the invention; and a plant or a part thereof which comprises a polynucleotide, a polypeptide, a vector or a cell according to the invention.
The invention further provides a polynucleotide coding for a signal sequence having a sequence set out in SEQ ID NO: 32241 to 33730 or having a sequence that differs 1 , 2 or 3 amino acids from the sequence set out in SEQ ID NO: 32241 to 33730.
Brief description of the drawings
Fig 1 : Map of pGBTOP for expression of genes in A. niger. Depicted are the gene of interest (GOI) expressed from the glucoamylase promoter (PglaA). In addition, the glucoamylase flank (3'glaA) of the expression cassette is depicted. In this application a gene of interest is the coding sequence of the protein or polypeptide of the invention as defined hereinafter.
Fig. 2 shows a schematic diagram of plasmid pEBA1006 that was used in bipartite gene-targeting method in combination with the pEBA expression vector containing the protein of the invention with the goal to replace the RePepA ORF and approximately 1500 nucleotides upstream of the start ATG codon by the expression cassette of the protein of the invention in Rasamsonia emersonii. The vector comprises the 3' part of the ble coding region, the A.nidulans trpC terminator, a lox71 site, a 2500 bp 3' flanking region of the RePepA ORF, and the backbone of pUC19 (Invitrogen, Breda, The Netherlands). The £. coli DNA was removed by digestion with restriction enzyme A/oil, prior to transformation of the R. emersonii strains.
Fig. 3 shows a schematic diagram of pEBA expression plasmid containing the protein of the invention that was used in bipartite gene-targeting method in combination with the pEBA1006 vector with the goal to replace the RePepA ORF and approximately 1500 nucleotides upstream of the start ATG codon by the expression cassette of the protein of the invention in Rasamsonia emersonii. The vector comprises a 1500 bp 5' flanking region 1 .5 kb upstream of the RePepA ORF for targeting in the RePepA locus, the protein of the invention-expression cassette consisting of R. emersonii promoter 2, the protein of the invention-coding region and the A.nidulans amdS terminator (TamdS), a lox66 site, the non-functional 5' part of the ble coding region (5' ble) driven by the A.nidulans gpdA promoter. The E. coli DNA was removed by digestion with restriction enzyme A/oil, prior to transformation of the R. emersonii strains.
Fig. 4 shows the pEBADEL.1 vector. Part of the vector fragment is used in bipartite gene-targeting method in combination with the pEBADEL2 vector with the goal to delete the ORF of the protein of the invention (GOI) in Rasamsonia emersonii. The vector comprises a 1200 bp 5' upstream flanking region of the ORF encoding the protein of the invention and the 5' part of the ble coding region driven by the A.nidulans gpdA promoter and the backbone of pUC19 (Invitrogen, Breda, The Netherlands). The E. coli DNA is removed by digestion with restriction enzyme Notl, prior to transformation of the R. emersonii strains.
Fig. 5 shows the pEBADEL.1 vector. Part of the vector fragment is used in bipartite gene-targeting method in combination with the pEBADEL.1 vector with the goal to delete the ORF encoding the protein of the invention (GOI) in Rasamsonia emersonii. The vector comprises the 3' part of the ble coding region, the A.nidulans trpC terminator, and a -1200 bp 3' flanking region downstream of the ORF encoding the protein of the invention, and the backbone of pUC19 (Invitrogen, Breda, The Netherlands). The E. coli DNA is removed by digestion with restriction enzyme Notl, prior to transformation of the R. emersonii strains.
Fig. 6 shows the strategy used to delete the ORF gene encoding the protein of the invention in R. emersonii. The deletion vectors comprise the overlapping non-functional ble selection marker fragments (split marker) flanked by loxP sites and 5' and 3' homologous regions of the gene encoding the protein of the invention (GOI) for targeting (1 ). The constructs integrate through triple homologous recombination (X) at the locus of the gene of the invention and at the overlapping homologous non-functional ble selection marker fragment (2) and replaces the genomic gene copy (3).
Brief description of the sequence listing
SEQ ID NO 1 to 33730 see Table 1.
SEQ ID NO 33731 Rasamsonia emersonii promoter 2
SEQ ID NO 33732 Aspergillus nidulans AmdS terminator Table 1
wild
genomi type
c DNA coding
sequen sequen
ce ce Amino mature signal
(includi (includi acid protein peptide
Gene of the ng stop ng stop sequen sequen sequen invention Function or activity codon) codon) ce ce ce
Gag/polymerase/env polyprotein,
Re01.g00010 putative 1 10251 20501
Re01.g00020 Putative uncharacterized protein 2 10252 20502
Re01.g00030 Reverse transcriptase, putative 3 10253 20503
Re01.g00040 Putative uncharacterized protein 4 10254 20504
Re01.g00050 MFS transporter, putative 5 10255 20505
Re01.g00060 C6 zinc finger domain protein 6 10256 20506
Re01.g00070 Uncharacterized protein 7 10257 20507 30751 32241
Re01.g00080 Putative uncharacterized protein 8 10258 20508
Re01.g00090 Transposase 9 10259 20509
Re01.g00100 Beta-ketoacyl synthase 10 10260 20510
Re01.g001 10 Putative cytochrome p450 protein 1 1 10261 2051 1
Re01.g00120 Uncharacterized protein 12 10262 20512
Putative uncharacterized protein
Re01.g00130 Fragment 13 10263 20513
Re01.g00140 Uncharacterized protein 14 10264 20514
RNA polymerase II mediator
Re01.g00150 complex protein (Med7), putative 15 10265 20515
Re01.g00160 PAP2 domain protein 16 10266 20516
Re01.g00170 Alpha/beta hydrolase, putative 17 10267 20517
Re01.g00180 Uncharacterized protein 18 10268 20518
Re01.g00190 hypothetical protein 19 10269 20519
Re01.g00200 hypothetical protein 20 10270 20520
Re01.g00210 Uncharacterized protein 21 10271 20521
Re01.g00220 Putative uncharacterized protein 22 10272 20522
F-actin capping protein alpha
Re01.g00230 subunit, putative 23 10273 20523
Re01.g00240 PEX1 1 domain protein 24 10274 20524
Re01.g00250 Putative uncharacterized protein 25 10275 20525
D-isomer specific 2-hydroxyacid
Re01.g00260 dehydrogenase family protein 26 10276 20526
Re01.g00270 Pc20g 15520 protein 27 10277 20527
Re01.g00290 Putative uncharacterized protein 28 10278 20528
Oxidoreductase, short chain
Re01.g00300 dehydrogenase/reductase family 29 10279 20529
Patched sphingolipid transporter
Re01.g00310 (Ncr1 ), putative 30 10280 20530 30752 32242
Re01.g00320 Importin beta-4 subunit, putative 31 10281 20531
Re01.g00330 Putative uncharacterized protein 32 10282 20532
Re01.g00340 Fumarylacetoacetate hydrolase 33 10283 20533 Re01.g00350 Predicted protein 34 10284 20534
Re01.g00360 Uncharacterized protein 35 10285 20535
FAD dependent oxidoreductase
Re01.g00370 superfamily 36 10286 20536
Sexual differentiation process
Re01.g00380 protein ISP4 37 10287 20537
Re01.g00390 Predicted protein 38 10288 20538
Re01.g00400 Putative uncharacterized protein 39 10289 20539 30753 32243
Similar to MFS alpha-glucoside
Re01.g00410 transporter 40 10290 20540
Short-chain
dehydrogenases/reductase,
Re01.g00420 putative 41 10291 20541
Re01.g00430 hypothetical protein 42 10292 20542
Re01.g00440 Uncharacterized protein 43 10293 20543
Re01.g00450 hypothetical protein 44 10294 20544
Re01.g00460 hypothetical protein 45 10295 20545
Re01.g00470 Putative uncharacterized protein 46 10296 20546
Re01.g00490 Uncharacterized protein 47 10297 20547
BZIP transcription factor AP-
Re01.g00500 1/Yap1 , putative 48 10298 20548
Re01.g00510 Putative uncharacterized protein 49 10299 20549
Re01.g00520 Uncharacterized protein 50 10300 20550 30754 32244
Re01.g00530 Putative uncharacterized protein 51 10301 20551
Re01.g00540 Nucleotide binding protein, putative 52 10302 20552
Re01.g00550 Lipase/esterase family protein 53 10303 20553
Zinc alcohol dehydrogenase,
Re01.g00560 putative 54 10304 20554
Siderochrome-iron transporter,
Re01.g00570 putative 55 10305 20555
Re01.g00580 hypothetical protein 56 10306 20556
Re01.g00590 Putative uncharacterized protein 57 10307 20557
Re01.g00600 Uncharacterized protein 58 10308 20558
Translation release factor eRF3,
Re01.g00610 putative 59 10309 20559
Re01.g00620 RanGTP-binding protein 60 10310 20560
Re01.g00630 Uncharacterized protein 61 1031 1 20561
Re01.g00640 Putative uncharacterized protein 62 10312 20562
Re01.g00650 DNA repair protein Rad4, putative 63 10313 20563
Re01.g00660 Pyruvate dehydrogenase, putative 64 10314 20564 30755 32245
Re01.g00670 Cell wall biogenesis protein 65 10315 20565 30756 32246
Re01.g00680 Uncharacterized protein 66 10316 20566
Re01.g00690 hypothetical protein 67 10317 20567
Re01.g00700 Putative uncharacterized protein 68 10318 20568
Viral A-type inclusion protein
Re01.g00710 repeat protein 69 10319 20569
Conserved glutamic acid-rich
Re01.g00720 protein 70 10320 20570
Re01.g00730 Phosphotyrosyl phosphatase 71 10321 20571 activator
Re01.g00740 Methyltransferase, putative 72 10322 20572
Re01.g00750 Pc22g17460 protein Precursor 73 10323 20573 30757 32247
Re01.g00760 hypothetical protein 74 10324 20574
Re01.g00770 Uncharacterized protein 75 10325 20575
Re01.g00780 Uncharacterized protein 76 10326 20576 30758 32248
Re01.g00790 Putative uncharacterized protein 77 10327 20577
Re01.g00800 Uncharacterized protein 78 10328 20578
Re01.g00810 Putative uncharacterized protein 79 10329 20579
Re01.g00820 Uncharacterized protein 80 10330 20580
Re01.g00830 Pc16g 10840 protein 81 10331 20581
Re01.g00840 MFS aflatoxin efflux pump, putative 82 10332 20582
Re01.g00850 Pc16g 10860 protein 83 10333 20583
Re01.g00860 Uncharacterized protein 84 10334 20584
Re01.g00870 Uncharacterized protein 85 10335 20585 30759 32249
Re01.g00880 Uncharacterized protein 86 10336 20586
Re01.g00890 Uncharacterized protein 87 10337 20587
Re01.g00900 Putative uncharacterized protein 88 10338 20588
Re01.g00910 Uncharacterized protein 89 10339 20589
Re01.g00920 Pc16g 10790 protein 90 10340 20590
Re01.g00930 Pc16g 10820 protein 91 10341 20591
Re01.g00940 Pc16g 10830 protein 92 10342 20592
Re01.g00950 Uncharacterized protein 93 10343 20593 30760 32250
Re01.g00960 Uncharacterized protein Fragment 94 10344 20594
Re01.g00970 Putative uncharacterized protein 95 10345 20595 30761 32251
Re01.g00980 Putative uncharacterized protein 96 10346 20596
Re01.g00990 Putative uncharacterized protein 97 10347 20597
Re01.g01000 DUF455 domain protein 98 10348 20598
Re01.g01010 Pc15g01570 protein 99 10349 20599
Re01.g01020 hypothetical protein 100 10350 20600
Re01.g01030 Predicted protein 101 10351 20601
Re01.g01040 Uncharacterized protein 102 10352 20602
Re01.g01050 Uncharacterized protein 103 10353 20603
Re01.g01060 Uncharacterized protein 104 10354 20604
Re01.g01070 Uncharacterized protein 105 10355 20605
Re01.g01080 hypothetical protein 106 10356 20606
Re01.g01090 Predicted protein 107 10357 20607
Phosphotransferase enzyme family
Re01.g01 100 protein 108 10358 20608
Re01.g01 1 10 Uncharacterized protein 109 10359 20609
Re01.g01 120 Putative dehydrogenase 1 10 10360 20610
Re01.g01 130 hypothetical protein 1 1 1 10361 2061 1 30762 32252
Major Facilitator Superfamily
Re01.g01 140 protein 1 12 10362 20612
5'-methylthioadenosine
Re01.g01 160 phosphorylase (Meu1 ), putative 1 13 10363 20613
6-phosphogluconate
dehydrogenase, decarboxylating
Re01.g01 170 EC=1.1.1.44 1 14 10364 20614 Re01.g01 180 3-dehydroshikimate dehydratase 1 15 10365 20615
Re01 .g01 190 hypothetical protein 1 16 10366 20616
Re01 .g01200 hypothetical protein 1 17 10367 20617
Re01 .g01210 hypothetical protein 1 18 10368 20618
Re01 .g01220 Uncharacterized protein 1 19 10369 20619
Delta-1 -pyrroline-5-carboxylate
Re01 .g01230 dehydrogenase PrnC 120 10370 20620
Re01 .g01240 Proline-specific permease 121 10371 20621
C6 transcription factor (PrnA),
Re01 .g01250 putative 122 10372 20622
Re01 .g01260 Uncharacterized protein 123 10373 20623
Re01 .g01270 Protein PrnX 124 10374 20624
Re01 .g01280 Proline oxidase PrnD 125 10375 20625
2-dehydropantoate 2-reductase
Re01 .g01290 EC=1.1.1.169 126 10376 20626
Re01 .g01300 Amidases 127 10377 20627 30763 32253
Re01 .g01310 Pc16g08650 protein 128 10378 20628
Re01 .g01320 Putative uncharacterized protein 129 10379 20629
Re01 .g01330 Putative uncharacterized protein 130 10380 20630
Re01 .g01340 Similar to An01g00290 131 10381 20631
Re01 .g01350 hypothetical protein 132 10382 20632
Re01 .g01360 ATP-binding cassette transporter 133 10383 20633
Re01 .g01370 Uncharacterized protein 134 10384 20634
Re01 .g01380 hypothetical protein 135 10385 20635
Re01 .g01390 Uncharacterized protein 136 10386 20636
Re01 .g01400 Uncharacterized protein 137 10387 20637 30764 32254
NADH-ubiquinone oxidoreductase
Re01 .g01410 304 kDa subunit 138 10388 20638 30765 32255
CCR4-NOT core complex subunit
Re01 .g01420 Not4, putative 139 10389 20639
Re01 .g01430 Sarcosine oxidase 140 10390 20640 30766 32256
2-oxoisovalerate dehydrogenase
complex alpha subunit, putative
Re01 .g01440 EC=1.2.4.4 141 10391 20641
Re01 .g01450 Beta-mannosidase 142 10392 20642 30767 32257
Re01 .g01460 PHP domain protein 143 10393 20643 30768 32258
Re01 .g01470 hypothetical protein 144 10394 20644 30769 32259
Re01 .g01480 Predicted protein 145 10395 20645
Re01 .g01490 Uncharacterized protein 146 10396 20646
Re01 .g01500 Putative uncharacterized protein 147 10397 20647 30770 32260
Re01 .g01510 Cytochrome P450, putative 148 10398 20648 30771 32261
Re01 .g01520 Hexose carrier protein, putative 149 10399 20649
Dimeric dihydrodiol
Re01 .g01530 dehydrogenase, putative 150 10400 20650
Peroxisomal 2,4-dienoyl-CoA
Re01 .g01540 reductase, putative 151 10401 20651 30772 32262
Re01 .g01550 hypothetical protein 152 10402 20652
Re01 .g01560 Uncharacterized protein 153 10403 20653 30773 32263
Re01 .g01570 hypothetical protein 154 10404 20654 Re01 .g01580 Predicted protein 155 10405 20655
Ankyrin repeat-containing protein,
Re01 .g01590 putative 156 10406 20656
Aspergillus niger contig
An08c0230, genomic contig
Re01 .g01600 EC=1.1.1.91 157 10407 20657
Re01 .g01610 AMP-binding enzyme, putative 158 10408 20658
Pheromone processing
Re01 .g01620 endoprotease Kex2 159 10409 20659 30774 32264
Re01 .g01630 Uncharacterized protein 160 10410 20660
Re01 .g01640 NmrA-like protein 161 1041 1 20661 30775 32265
Re01 .g01650 Putative uncharacterized protein 162 10412 20662
Re01 .g01660 Putative uncharacterized protein 163 10413 20663
Re01 .g01670 DEAD/DEAH box helicase, putative 164 10414 20664
PhosphatidylinositoLUDP-GlcNAc
Re01 .g01680 transferase subunit PIG-A 165 10415 20665
Re01 .g01690 Uncharacterized protein 166 10416 20666
ADP-ribosylation factor family
Re01 .g01700 protein 167 10417 20667
Re01 .g01710 Uncharacterized protein 168 10418 20668
mRNA splicing factor (Prp18),
Re01 .g01720 putative 169 10419 20669
Re01 .g01730 Uncharacterized protein 170 10420 20670
Re01 .g01740 Putative uncharacterized protein 171 10421 20671
Re01 .g01750 Putative uncharacterized protein 172 10422 20672
Re01 .g01760 FYVE domain protein 173 10423 20673
Re01 .g01770 Uncharacterized protein 174 10424 20674
NOL1/NOP2/sun domain protein,
Re01 .g01780 putative 175 10425 20675
Re01 .g01790 Putative uncharacterized protein 176 10426 20676
Re01 .g01800 Uncharacterized protein Fragment 177 10427 20677
Long-chain-alcohol oxidase
Re01 .g01810 EC=1.1.3.20 178 10428 20678
Re01 .g01820 Uncharacterized protein 179 10429 20679
Sphinganine hydroxylase Sur2,
Re01 .g01830 putative 180 10430 20680
Re01 .g01840 TCTP family protein 181 10431 20681
Re01 .g01850 Zn(ll)2Cys6 transcription factor 182 10432 20682
Signal recognition particle 19 kDa
Re01 .g01860 protein homolog 183 10433 20683
Re01 .g01870 Uncharacterized protein 184 10434 20684
Re01 .g01880 Putative uncharacterized protein 185 10435 20685
Cleavage and polyadenylation
specifity factor, 73 kDa subunit,
Re01 .g01890 putative 186 10436 20686
Re01 .g01900 Uncharacterized protein 187 10437 20687
Re01 .g01910 Protein kinase 188 10438 20688
Re01 .g01920 Uncharacterized protein 189 10439 20689
Re01 .g01930 Mitochondrial cation transporter, 190 10440 20690 putative
Re01.g01940 Amidase 191 10441 20691
Feruloyl esterase A EC=3.1.1.73
Re01.g01950 Precursor 192 10442 20692 30776 32266
Alpha-acetolactate decarboxylase,
Re01.g01960 putative 193 10443 20693 30777 32267
Re01.g01970 Uncharacterized protein 194 10444 20694
Re01.g01980 PHD finger domain protein 195 10445 20695
Re01.g01990 Putative uncharacterized protein 196 10446 20696
Re01.g02000 Uncharacterized protein 197 10447 20697
Re01.g02010 hypothetical protein 198 10448 20698
Re01.g02020 Uncharacterized protein 199 10449 20699
Re01.g02030 Carotenoid cleavage dioxygenase 200 10450 20700
Re01.g02040 hypothetical protein 201 10451 20701
Re01.g02050 hypothetical protein 202 10452 20702
Re01.g02060 Putative uncharacterized protein 203 10453 20703
Re01.g02070 Mis12 domain protein 204 10454 20704
Re01.g02080 Putative uncharacterized protein 205 10455 20705
Re01.g02090 Uncharacterized protein 206 10456 20706
Swrl p complex component (Swc5),
Re01.g02100 putative 207 10457 20707
Re01.g021 10 Actibind 208 10458 20708 30778 32268
Re01.g02120 hypothetical protein 209 10459 20709
Re01.g02130 MFS multidrug transporter, putative 210 10460 20710
C2H2 type conidiation transcription
Re01.g02140 factor BrIA 21 1 10461 2071 1
Re01.g02150 hypothetical protein 212 10462 20712
Re01.g02160 hypothetical protein 213 10463 20713
Re01.g02170 Uncharacterized protein 214 10464 20714
Re01.g02180 Uncharacterized protein 215 10465 20715
Eukaryotic translation initiation
factor subunit elF2B-gamma,
Re01.g02190 putative 216 10466 20716 30779 32269
Re01.g02200 hypothetical protein 217 10467 20717
Re01.g02210 hypothetical protein 218 10468 20718
Re01.g02220 Putative uncharacterized protein 219 10469 20719
Re01.g02230 Uncharacterized protein 220 10470 20720
Re01.g02240 Fatty acid elongase 221 10471 20721
Re01.g02250 hypothetical protein 222 10472 20722 30780 32270
Glyceraldehyde 3-phosphate
Re01.g02260 dehydrogenase EC=1.2.1.12 223 10473 20723
Pseudouridine synthase
Re01.g02270 TruD/Pus7, putative 224 10474 20724
Re01.g02280 Putative uncharacterized protein 225 10475 20725 30781 32271
Re01.g02290 Putative uncharacterized protein 226 10476 20726
ADP-ribose 1 "-phosphate
Re01.g02300 phosphatase EC=3.1.3.84 227 10477 20727
Macrophage migration inhibitory
Re01.g02310 factor family protein 228 10478 20728 Re01.g02320 Putative arginase family protein 229 10479 20729 30782 32272
SUN domain protein (Adg3),
Re01.g02330 putative 230 10480 20730 30783 32273
Benzoate 4-monooxygenase
Re01.g02340 cytochrome P450 231 10481 20731
Re01.g02350 DUF292 domain protein 232 10482 20732
Re01.g02360 MFS transporter, putative 233 10483 20733
Re01.g02370 Putative uncharacterized protein 234 10484 20734 30784 32274
Re01.g02380 Uncharacterized protein 235 10485 20735
Re01.g02390 AP-2 complex subunit sigma 236 10486 20736
Re01.g02400 Diphthine synthase, putative 237 10487 20737
SAGA-like transcriptional
Re01.g02410 regulatory complex subunit Spt3 238 10488 20738
Re01.g02420 Blue light-inducible protein Bli-3 239 10489 20739
Re01.g02430 hypothetical protein 240 10490 20740
Re01.g02440 F-box domain protein 241 10491 20741
C2H2 finger domain-containing
Re01.g02450 protein 242 10492 20742
Re01.g02460 Uncharacterized protein 243 10493 20743
Re01.g02470 Putative uncharacterized protein 244 10494 20744
Histidinol-phosphate
Re01.g02480 aminotransferase 245 10495 20745
Re01.g02490 hypothetical protein 246 10496 20746
Re01.g02500 hypothetical protein 247 10497 20747
Re01.g02510 hypothetical protein 248 10498 20748
Re01.g02520 Putative uncharacterized protein 249 10499 20749
Integral membrane protein,
Re01.g02530 putative 250 10500 20750
Catalytic activity: Nucleoside
triphosphate + RNA(n) =
Pyrophosphate + RNA(n+1 )
Re01.g02540 EC=2.7.7.6 251 10501 20751
Nuclear segregation protein (Bfr1 ),
putative (AFU orthologue
Re01.g02550 AFUAJ G14120) 252 10502 20752
Re01.g02560 Uncharacterized protein 253 10503 20753 30785 32275
Phosphatidylglycerol specific
phospholipase C, putative
Re01.g02570 EC=3.1.4.3 254 10504 20754 30786 32276
Re01.g02580 Uncharacterized protein 255 10505 20755
Re01.g02590 Uncharacterized protein 256 10506 20756
Re01.g02600 hypothetical protein 257 10507 20757
Re01.g02610 Uncharacterized protein 258 10508 20758 30787 32277
Re01.g02620 Beta-galactosidase EC=3.2.1.23 259 10509 20759 30788 32278
Phytanoyl-CoA dioxygenase,
Re01.g02630 putative 260 10510 20760
Re01.g02640 Methyltransferase (Ncl1 ), putative 261 1051 1 20761
Re01.g02650 Alpha/beta-Hydrolase 262 10512 20762
Re01.g02660 Class II aldolase/adducin domain 263 10513 20763 protein
Re01.g02670 Uncharacterized protein 264 10514 20764
Adenylosuccinate synthetase
Re01.g02680 EC=6.3.4.4 265 10515 20765
Re01.g02690 DnaJ domain-containing protein 266 10516 20766
C6 transcription factor (UaY),
Re01.g02700 putative 267 10517 20767
Re01.g02710 MFS multidrug transporter, putative 268 10518 20768
Re01.g02720 GTP-binding protein Obg 269 10519 20769 30789 32279
Re01.g02730 JmjC domain protein, putative 270 10520 20770
Re01.g02740 DUF1014 domain protein 271 10521 20771
Re01.g02750 Methyltransferase, putative 272 10522 20772
Peroxisome biosynthesis protein
Re01.g02760 (Peroxine-7), putative 273 10523 20773
Re01.g02770 Putative uncharacterized protein 274 10524 20774
Re01.g02780 CUE domain protein, putative 275 10525 20775
Re01.g02790 Uncharacterized protein 276 10526 20776
Re01.g02800 hypothetical protein 277 10527 20777 30790 32280
Ubiquitin-conjugating enzyme,
Re01.g02810 putative 278 10528 20778
Re01.g02820 Putative uncharacterized protein 279 10529 20779
Homeobox and C2H2 transcription
Re01.g02830 factor, putative 280 10530 20780
Re01.g02840 Urea carboxylase 281 10531 20781
Re01.g02850 Lactam utilization protein LamB 282 10532 20782
Re01.g02860 F-box domain-containing protein 283 10533 20783
Re01.g02870 Uncharacterized protein 284 10534 20784 30791 32281
Cell division control protein 45,
Re01.g02880 putative 285 10535 20785 30792 32282
Re01.g02890 Mannosidase MsdS EC=3.2.1.1 13 286 10536 20786 30793 32283
Transcriptional regulatory protein
Re01.g02900 moc3 287 10537 20787
Phosphoribosyl-AMP
Re01.g02910 cyclohydrolase 288 10538 20788
U3 small nucleolar RNA-associated
Re01.g02920 protein Utp1 1 , putative 289 10539 20789
Re01.g02930 Putative uncharacterized protein 290 10540 20790
Transcription initiation factor TFIID,
Re01.g02940 31 kD subunit, putative 291 10541 20791
Re01.g02950 Lipin Smp2, putative 292 10542 20792
Re01.g02960 Fibronectin type III domain protein 293 10543 20793
TRNAHis guanylyltransferase,
Re01.g02970 putative 294 10544 20794
Re01.g02980 Putative uncharacterized protein 295 10545 20795
Re01.g02990 WD domain protein 296 10546 20796 30794 32284
Re01.g03000 hypothetical protein 297 10547 20797
Re01.g03020 WD domain-containing protein 298 10548 20798
DNA-directed RNA polymerase
Re01.g03030 EC=2.7.7.6 299 10549 20799 Re01.g03040 Putative uncharacterized protein 300 10550 20800 30795 32285
DNA repair protein Dds20/Sfr1 ,
Re01.g03050 putative 301 10551 20801
Beta-glucosidase EC=3.2.1.21
Re01.g03060 EC=3.2.1.21 302 10552 20802
Re01.g03070 Kelch motif domain protein 303 10553 20803
Re01.g03080 WD-repeat containing protein slpl 304 10554 20804
Transcription factor TFIIA complex
Re01.g03090 subunit Toa1 , putative 305 10555 20805
Re01.g03100 C6 transcription factor 306 10556 20806
Re01.g031 10 Uncharacterized protein 307 10557 20807
C2H2 transcription factor (Sfp1 ),
Re01.g03120 putative 308 10558 20808
Re01.g03130 tRNA-dihydrouridine synthase 3 309 10559 20809
Re01.g03140 BAP31 domain protein, putative 310 10560 20810 30796 32286
Mitochondrial inheritance
Re01.g03150 component mdm12 31 1 10561 2081 1
Re01.g03160 Predicted protein 312 10562 20812
Re01.g03170 hypothetical protein 313 10563 20813 30797 32287
Serine/threonine protein kinase
Re01.g03180 (Kin4), putative 314 10564 20814
Re01.g03190 Putative uncharacterized protein 315 10565 20815
Re01.g03200 Acyl-CoA dehydrogenase, putative 316 10566 20816 30798 32288
Re01.g03210 BZIP transcription factor, putative 317 10567 20817
Re01.g03220 Uncharacterized protein Fragment 318 10568 20818
Re01.g03230 Uncharacterized protein 319 10569 20819
Re01.g03240 Uncharacterized protein 320 10570 20820
Re01.g03250 Amidase 321 10571 20821
CAMP-specific phosphodiesterase,
Re01.g03260 putative 322 10572 20822
Re01.g03270 hypothetical protein 323 10573 20823
Endosomal SPRY domain protein,
Re01.g03280 putative 324 10574 20824
Probable Xaa-Pro aminopeptidase
Re01.g03290 ACLA_020440 EC=3.4.1 1.9 325 10575 20825
Protein translocation complex
Re01.g03300 componenet (Npl 1), putative 326 10576 20826
Re01.g03310 C6 transcription factor 327 10577 20827
Re01.g03320 Uncharacterized protein 328 10578 20828
Re01.g03330 Sugar 1 ,4-lactone oxidase, putative 329 10579 20829
Re01.g03340 Gelsolin repeat protein, putative 330 10580 20830
Re01.g03350 Uncharacterized protein 331 10581 20831
Re01.g03360 Uncharacterized protein 332 10582 20832
Re01.g03370 Putative uncharacterized protein 333 10583 20833
2-isopropylmalate synthase
Re01.g03380 EC=2.3.3.13 334 10584 20834
AMP binding domain protein,
Re01.g03390 putative 335 10585 20835
Re01.g03400 40S ribosomal protein S5 336 10586 20836 Re01.g03410 SDA1 domain protein 337 10587 20837
Re01.g03420 Uncharacterized protein 338 10588 20838
Hsp70 family chaperone
Re01.g03430 Lhs1/Orp150, putative 339 10589 20839 30799 32289
MtDNA inheritance protein Dml 1 ,
Re01.g03440 putative 340 10590 20840
Re01.g03450 Uncharacterized protein 341 10591 20841
Re01.g03460 Putative uncharacterized protein 342 10592 20842
Re01.g03470 EBP domain-containing protein 343 10593 20843
Re01.g03480 Putative uncharacterized protein 344 10594 20844
DsDNA-dependent ATPase
Re01.g03490 (Rad54b), putative 345 10595 20845
Re01.g03500 Choline transport protein, putative 346 10596 20846
Re01.g03510 Putative uncharacterized protein 347 10597 20847
Polysaccharide deacetylase family
Re01.g03520 protein 348 10598 20848 30800 32290
Heat shock protein
Re01.g03530 Hsp98/Hsp104/ClpA, putative 349 10599 20849
Re01.g03540 Putative uncharacterized protein 350 10600 20850
Re01.g03550 Autophagy protein Atg27 351 10601 20851 30801 32291
Prefoldin subunit 4, putative
Re01.g03560 (AFlLorthologue AFUAJ G15240) 352 10602 20852
Re01.g03570 C6 transcription factor, putative 353 10603 20853
Re01.g03580 Uncharacterized protein 354 10604 20854 30802 32292
Re01.g03590 Putative uncharacterized protein 355 10605 20855
Re01.g03600 Putative uncharacterized protein 356 10606 20856
Re01.g03610 Hsp70 family protein 357 10607 20857
Re01.g03620 hypothetical protein 358 10608 20858
Re01.g03630 Putative uncharacterized protein 359 10609 20859 30803 32293
Re01.g03640 Putative uncharacterized protein 360 10610 20860
Re01.g03650 Acyl-CoA thioesterase II 361 1061 1 20861
Re01.g03660 Uncharacterized protein 362 10612 20862
Re01.g03670 hypothetical protein 363 10613 20863
Re01.g03680 Uncharacterized protein 364 10614 20864
Re01.g03690 hypothetical protein 365 10615 20865
Alpha-amylase, putative
Re01.g03700 EC=3.2.1.98 366 10616 20866 30804 32294
Mitochondrial phosphate carrier
Re01.g03710 protein (Mir1 ), putative 367 10617 20867 30805 32295
Re01.g03720 Uncharacterized protein 368 10618 20868
Re01.g03740 Uncharacterized protein 369 10619 20869
Re01.g03750 Uncharacterized protein 370 10620 20870
Re01.g03760 Putative uncharacterized protein 371 10621 20871 30806 32296
Homoserine acetyltransferase
Re01.g03770 family protein 372 10622 20872
Re01.g03780 Poly(A) polymerase Pap 373 10623 20873
Re01.g03790 Uncharacterized protein 374 10624 20874
Manganese superoxide dismutase
Re01.g03800 AAC36583-Penicillium 375 10625 20875 chrysogenum
Re01.g03810 Uncharacterized protein 376 10626 20876
Re01.g03820 Uncharacterized protein 377 10627 20877
Re01.g03830 Amidase signature (AS) enzyme 378 10628 20878
Oxidoreductase, short-chain
Re01.g03840 dehydrogenase/reductase family 379 10629 20879
Re01.g03850 Putative uncharacterized protein 380 10630 20880
Re01.g03860 Putative uncharacterized protein 381 10631 20881
Re01.g03870 Putative uncharacterized protein 382 10632 20882
Pyridine nucleotide-disulphide
Re01.g03880 oxidoreductase, putative 383 10633 20883 30807 32297
Re01.g03890 Methyltransferase, putative 384 10634 20884
Re01.g03900 Adenylate cyclase, putative 385 10635 20885
Re01.g03910 Predicted protein 386 10636 20886
Re01.g03920 hypothetical protein 387 10637 20887 30808 32298
Re01.g03930 Ankyrin repeat protein 388 10638 20888
Re01.g03940 Putative uncharacterized protein 389 10639 20889
Re01.g03950 Aminotransferase, putative 390 10640 20890
Re01.g03960 Putative uncharacterized protein 391 10641 20891 30809 32299
Re01.g03970 Uncharacterized protein 392 10642 20892
Re01.g03980 Metalloreductase 393 10643 20893
2-deoxy-D-gluconate 3-
Re01.g03990 dehydrogenase, putative 394 10644 20894 30810 32300
Re01.g04000 Uncharacterized protein 395 10645 20895
3-ketoacyl-acyl carrier protein
reductase, putative
Re01.g04010 (AFU.orthologue AFUAJ G14380) 396 10646 20896
Zinc-dependent alcohol
Re01.g04020 dehydrogenase, putative 397 10647 20897
Hydroxyisocaproate
Re01.g04030 dehydrogenase 398 10648 20898
Re01.g04040 Uncharacterized protein 399 10649 20899
Re01.g04050 Cation diffusion facilitator 1 400 10650 20900
Re01.g04060 Putative uncharacterized protein 401 10651 20901
Re01.g04070 Ankyrin repeat protein 402 10652 20902
Re01.g04080 ABC transporter 403 10653 20903
Re01.g04090 UBX domain protein 404 10654 20904
Re01.g04100 hypothetical protein 405 10655 20905
PAB-dependent poly(A)-specific
Re01.g041 10 ribonuclease subunit pan3 406 10656 20906
Re01.g04120 Small nuclear ribonucleoprotein 407 10657 20907
Re01.g04130 hypothetical protein 408 10658 20908
Re01.g04140 hypothetical protein 409 10659 20909
Re01.g04150 Uncharacterized protein 410 10660 20910
Re01.g04160 Catechol dioxygenase, putative 41 1 10661 2091 1
TGF beta receptor associated
Re01.g04170 protein 1 , putative 412 10662 20912
Golgi membrane protein (Coy1 ),
Re01.g04180 putative 413 10663 20913 Re01.g04190 Putative uncharacterized protein 414 10664 20914
Similarity to hypothetical protein
Re01.g04200 CAC28784.2 415 10665 20915 3081 1 32301
Re01.g04210 Fibrillarin 416 10666 20916
Re01.g04220 Monooxygenase, putative 417 10667 20917
Nucleoside-diphosphate-sugar
Re01.g04230 epimerase, putative 418 10668 20918
Mitochondrial processing peptidase
Re01.g04240 beta subunit, putative 419 10669 20919
Oxidoreductase, zinc-binding
Re01.g04250 dehydrogenase family, putative 420 10670 20920
Succinate dehydrogenase subunit
Re01.g04260 CybS 421 10671 20921
Re01.g04270 Septum formation protein Maf 422 10672 20922
Re01.g04280 Pc06g01830 protein 423 10673 20923
Re01.g04290 Uncharacterized protein 424 10674 20924
Putative endoglucanase v-like
Re01.g04300 protein 425 10675 20925 30812 32302
Re01.g04310 hypothetical protein 426 10676 20926
Re01.g04320 hypothetical protein 427 10677 20927
Re01.g04330 Uncharacterized protein 428 10678 20928 30813 32303
Re01.g04340 Predicted protein 429 10679 20929
Putative uncharacterized protein
Re01.g04350 An04g04080 430 10680 20930
Re01.g04360 Putative uncharacterized protein 431 10681 20931
Re01.g04370 Uncharacterized protein 432 10682 20932
Re01.g04380 Putative uncharacterized protein 433 10683 20933
Re01.g04390 Importin beta-1 subunit 434 10684 20934
Re01.g04400 Remark: YS24 is part of the small 435 10685 20935
Phosphoglycerate mutase family
Re01.g04410 protein 436 10686 20936
Re01.g04420 Uncharacterized protein Fragment 437 10687 20937
Phosphatidylserine decarboxylase,
Re01.g04430 putative 438 10688 20938
Re01.g04440 Retrograde regulation protein 2 439 10689 20939
Re01.g04450 Uncharacterized protein 440 10690 20940
Anaphase promoting complex
Re01.g04460 subunit 10 (APC10), putative 441 10691 20941
3-isopropylmalate dehydrogenase
Re01.g04470 Leu2A 442 10692 20942
Re01.g04480 Uncharacterized protein 443 10693 20943
Re01.g04490 Uncharacterized protein 444 10694 20944
Re01.g04500 Putative uncharacterized protein 445 10695 20945 30814 32304
Re01.g04510 Uncharacterized protein 446 10696 20946 30815 32305
Re01.g04520 Predicted protein 447 10697 20947
Re01.g04530 Putative uncharacterized protein 448 10698 20948
Re01.g04540 Polyketide synthase 449 10699 20949
NAD(P)-binding Rossmann-fold
Re01.g04550 containing protein 450 10700 20950 30816 32306 Re01.g04560 Uncharacterized protein 451 10701 20951
Re01.g04570 Putative uncharacterized protein 452 10702 20952
Re01.g04580 Putative uncharacterized protein 453 10703 20953
RNA splicing factor (Pad-1 ),
Re01.g04590 putative 454 10704 20954
Ceramide very long chain fatty acid
Re01.g04600 hydroxylase SCS7 455 10705 20955
Re01.g04610 Putative uncharacterized protein 456 10706 20956
Re01.g04620 Ferrooxidoreductase Fet3 457 10707 20957 30817 32307
Re01.g04630 Uncharacterized protein 458 10708 20958
Re01.g04640 Putative uncharacterized protein 459 10709 20959
Re01.g04650 Uncharacterized protein 460 10710 20960
Re01.g04660 Coatomer subunit delta, putative 461 1071 1 20961
Conserved glutamic acid-rich
Re01.g04670 protein 462 10712 20962
Re01.g04680 Uncharacterized conserved protein 463 10713 20963
Re01.g04690 Sacl domain protein 464 10714 20964
Re01.g04700 Importin beta-2 subunit, putative 465 10715 20965
Re01.g04710 Putative uncharacterized protein 466 10716 20966
Re01.g04720 Dockerin type 1 467 10717 20967
Re01.g04730 MFS hexose transporter 468 10718 20968
Re01.g04740 Predicted protein 469 10719 20969
Re01.g04750 Uncharacterized protein 470 10720 20970 30818 32308
Re01.g04760 Ubiquitin hydrolase, putative 471 10721 20971
Re01.g04770 Choline kinase, putative 472 10722 20972
Re01.g04780 Non-hemolytic phospholipase C 473 10723 20973 30819 32309
Re01.g04790 Multicopper oxidase, putative 474 10724 20974
Re01.g04800 Auxin Efflux Carrier superfamily 475 10725 20975
MAP kinase kinase (Pbs2),
Re01.g04820 putative 476 10726 20976
Glutathione oxidoreductase Girl ,
Re01.g04830 putative EC=1.8.1.7 477 10727 20977
Re01.g04840 MFS transporter 478 10728 20978
Re01.g04850 Uncharacterized protein 479 10729 20979
Re01.g04860 Enoyl-CoA hydratase 480 10730 20980
Re01.g04870 Uncharacterized protein 481 10731 20981
Re01.g04880 hypothetical protein 482 10732 20982
Re01.g04890 Putative uncharacterized protein 483 10733 20983
Putative uncharacterized protein
Re01.g04900 An1 1 g10270 484 10734 20984
Re01.g04910 Choline dehydrogenase 485 10735 20985 30820 32310
Re01.g04920 Uncharacterized protein 486 10736 20986 30821 3231 1
Re01.g04930 Uncharacterized protein 487 10737 20987
Re01.g04940 Uncharacterized protein 488 10738 20988
Re01.g04950 Uncharacterized protein 489 10739 20989
Re01.g04960 Thioredoxin reductase GliT-like 490 10740 20990
Re01.g04970 hypothetical protein 491 10741 20991
Putative uncharacterized protein
Re01.g04980 Fragment 492 10742 20992 Re01.g04990 Putative uncharacterized protein 493 10743 20993 30822 32312
Re01.g05000 Predicted protein 494 10744 20994
Re01.g05010 Putative transporter 495 10745 20995
Re01.g05020 Uncharacterized protein 496 10746 20996
Re01.g05030 Transposase 497 10747 20997
Re01.g05040 Putative uncharacterized protein 498 10748 20998
Re01.g05050 Lectin C-type domain protein 499 10749 20999
Re01.g05060 Uncharacterized protein 500 10750 21000
Peptidase family M20/M25/M40
Re01.g05070 protein 501 10751 21001
Re01.g05080 hypothetical protein 502 10752 21002
NADPH:adrenodoxin
oxidoreductase, mitochondrial
Re01.g05090 EC=1.18.1.6 503 10753 21003
Re01.g05100 GABA permease, putative 504 10754 21004
Re01.g051 10 Predicted protein 505 10755 21005 30823 32313
Re01.g05120 Uncharacterized protein 506 10756 21006 30824 32314
Re01.g05130 hypothetical protein 507 10757 21007 30825 32315
Re01.g05140 Putative uncharacterized protein 508 10758 21008
Re01.g05150 Uncharacterized protein 509 10759 21009
Re01.g05160 Uncharacterized protein 510 10760 21010
Re01.g05170 DUF726 domain protein 51 1 10761 2101 1
Re01.g05180 Vesicular-fusion protein sec17 512 10762 21012
Small nucleolar ribonucleoprotein
Re01.g05190 complex subunit, putative 513 10763 21013
Pre-rRNA processing protein Tsr1 ,
Re01.g05200 putative 514 10764 21014
Re01.g05210 Urease accessory protein ureG 515 10765 21015
Re01.g05220 hypothetical protein 516 10766 21016
Re01.g05230 PtaB protein, putative 517 10767 21017
Re01.g05240 Spastin 518 10768 21018
Re01.g05250 hypothetical protein 519 10769 21019
Re01.g05260 Uncharacterized protein 520 10770 21020
Re01.g05270 hypothetical protein 521 10771 21021
Re01.g05290 Uncharacterized protein 522 10772 21022
Re01.g05300 hypothetical protein 523 10773 21023 30826 32316
PAPA-1 -like conserved region
Re01.g05310 protein 524 10774 21024 30827 32317
Peroxisomal membrane anchor
Re01.g05320 protein, putative 525 10775 21025
Protein transport protein (SEC31 ),
Re01.g05330 putative 526 10776 21026 30828 32318
Peptidyl prolyl cis-trans isomerase
Re01.g05340 Cyclophilin, putative 527 10777 21027
Re01.g05350 Uncharacterized protein 528 10778 21028
Re01.g05360 Putative uncharacterized protein 529 10779 21029
FAD dependent oxidoreductase,
Re01.g05370 putative 530 10780 21030 30829 32319
Re01.g05380 Putative uncharacterized protein 531 10781 21031 Re01.g05390 Uncharacterized protein 532 10782 21032
Re01.g05400 Putative uncharacterized protein 533 10783 21033
Mitochondrial co-chaperone GrpE,
Re01.g05410 putative 534 10784 21034
Re01.g05420 Uncharacterized protein 535 10785 21035
Calcineurin binding protein,
Re01.g05430 putative 536 10786 21036
Arginyl-tRNA—protein transferase 1
Re01.g05440 EC=2.3.2.8 537 10787 21037
Re01.g05450 Uncharacterized protein 538 10788 21038
Re01.g05460 RNA polymerase II subunit 3 539 10789 21039
Re01.g05470 Putative uncharacterized protein 540 10790 21040
Re01.g05480 Putative uncharacterized protein 541 10791 21041
Re01.g05490 Putative uncharacterized protein 542 10792 21042
Re01.g05500 3' exoribonuclease family protein 543 10793 21043
Re01.g05510 Meiosis induction protein kinase 544 10794 21044
Re01.g05520 Uncharacterized protein 545 10795 21045
Re01.g05530 Putative uncharacterized protein 546 10796 21046
Re01.g05540 Uncharacterized protein 547 10797 21047
Re01.g05550 Putative uncharacterized protein 548 10798 21048
OB-fold nucleic acid binding
Re01.g05560 domain-containing protein 549 10799 21049
Cytidine and deoxycytidylate
deaminase zinc-binding domain
Re01.g05570 protein 550 10800 21050
Re01.g05580 DnaJ domain protein 551 10801 21051
Universal stress protein family
Re01.g05590 domain protein 552 10802 21052
Re01.g05600 Uncharacterized protein 553 10803 21053
Re01.g05610 Reverse transcriptase, putative 554 10804 21054
Re01.g05620 Uncharacterized protein 555 10805 21055
Re01.g05630 Salicylate hydroxylase 556 10806 21056
Re01.g05640 Uncharacterized protein 557 10807 21057 30830 32320
Re01.g05650 Vacuolar ATP synthase subunit B 558 10808 21058
Bifunctional tryptophan synthase
Re01.g05660 TRPB 559 10809 21059
Re01.g05670 Transcriptional regulator Medusa 560 10810 21060
Re01.g05680 Putative uncharacterized protein 561 1081 1 21061
Re01.g05690 Pc22g 13390 protein 562 10812 21062
Re01.g05700 GYF domain protein 563 10813 21063
Re01.g05710 Aminotransferase family protein 564 10814 21064
Re01.g05720 Pc21 g22720 protein 565 10815 21065
RING finger domain protein,
Re01.g05730 putative 566 10816 21066
Mitochondrial membrane fission
Re01.g05740 protein 567 10817 21067
Re01.g05750 Putative uncharacterized protein 568 10818 21068
Re01.g05760 Uncharacterized protein 569 10819 21069 30831 32321
Re01.g05770 Uncharacterized protein 570 10820 21070 RNA polymerase II transcription
mediator complex subunit Srb7,
Re01.g05780 putative 571 10821 21071
Re01.g05790 SNF2 family helicase/ATPase 572 10822 21072
Phosphatidylinositol 4-kinase type
Re01.g05800 II subunit alpha, putative 573 10823 21073
GATA transcription factor (AreB),
Re01.g05810 putative 574 10824 21074
Re01.g05820 MFS transporter, putative 575 10825 21075
Similarity to hypothetical
Re01.g05830 membrane protein YDR105c 576 10826 21076 30832 32322
DNA mismatch repair protein
Re01.g05840 (Pms1), putative 577 10827 21077
Re01.g05850 Uncharacterized protein 578 10828 21078
Re01.g05860 Chitin synthase 579 10829 21079 30833 32323
Re01.g05870 Chitin synthase ChsE 580 10830 21080
Re01.g05880 KH domain protein 581 10831 21081
Re01.g05890 Uncharacterized protein 582 10832 21082
Re01.g05900 Pyrimidine 5'-nucleotidase, putative 583 10833 21083
Re01.g05910 Dynactin, putative 584 10834 21084
Re01.g05920 Uncharacterized protein 585 10835 21085
Re01.g05930 Uncharacterized protein 586 10836 21086 30834 32324
Re01.g05940 DUF300 domain protein 587 10837 21087
Re01.g05950 Uncharacterized protein 588 10838 21088
Translation elongation factor EF-2
Re01.g05960 subunit, putative 589 10839 21089
CCCH zinc finger and RRM
Re01.g05970 domain protein 590 10840 21090
Re01.g05980 Uncharacterized protein 591 10841 21091
N-terminal nucleophile
Re01.g05990 aminohydrolases (Ntn hydrolases) 592 10842 21092
Re01.g06000 Predicted protein 593 10843 21093
Re01.g06010 Myo-inositol transporter 594 10844 21094
Benzoate 4-monooxygenase
Re01.g06020 cytochrome P450 595 10845 21095
NADPH-cytochrome P450
Re01.g06030 reductase EC=1.6.2.4 596 10846 21096 30835 32325
Lactoylglutathione lyase (Glo1 ),
Re01.g06040 putative 597 10847 21097
Re01.g06050 Putative uncharacterized protein 598 10848 21098
Ribosome biogenesis protein
Re01.g06060 (Bms1), putative 599 10849 21099
Meiotic chromosome segregation
Re01.g06070 protein 600 10850 21 100
Re01.g06080 Putative uncharacterized protein 601 10851 21 101
Re01.g06090 Uncharacterized protein 602 10852 21 102
Mitochondrial pyruvate
Re01.g06100 dehydrogenase kinase, putative 603 10853 21 103
Re01.g061 10 Putative uncharacterized protein 604 10854 21 104 30836 32326 Thiamine pyrophosphate-requiring
Re01.g06120 enzyme 605 10855 21105
Aromatic aminotransferase Aro8,
Re01.g06130 putative 606 10856 21106
Re01.g06140 hypothetical protein 607 10857 21107
Serine/threonin protein kinase,
Re01.g06150 putative 608 10858 21108
Endonuclease/exonuclease/phosp
Re01.g06160 hatase family protein 609 10859 21109
Re01.g06170 hypothetical protein 610 10860 21110 30837 32327
Re01.g06180 Uncharacterized protein 611 10861 21111
Calcium/calmodulin-dependent
Re01.g06190 protein kinase 612 10862 21112
Ubiquitin conjugating enzyme,
Re01.g06200 putative 613 10863 21113
NADH-ubiquinone oxidoreductase
Re01.g06210 49 kDa subunit, putative 614 10864 21114
DNA-directed RNA polymerase I
and III subunit Rpc40, putative
Re01.g06220 EC=2.7.7.6 615 10865 21115
NEDD8 activating enzyme (UbaC),
Re01.g06230 putative 616 10866 21116
Re01.g06240 Uncharacterized protein 617 10867 21117
Re01.g06250 Uncharacterized protein 618 10868 21118
Re01.g06260 Putative uncharacterized protein 619 10869 21119
Re01.g06270 Putative uncharacterized protein 620 10870 21120
Re01.g06280 Putative uncharacterized protein 621 10871 21121
Re01.g06290 Uncharacterized protein 622 10872 21122
Re01.g06310 hypothetical protein 623 10873 21123 30838 32328
Re01.g06320 Putative uncharacterized protein 624 10874 21124 30839 32329
Actin cytoskeleton organization
Re01.g06330 protein App1, putative 625 10875 21125
Putative uncharacterized protein
Re01.g06340 An11g00410 Precursor 626 10876 21126
Serine/threonine-protein
Re01.g06350 phosphatase EC=3.1.3.16 627 10877 21127
Short chain
Re01.g06360 dehydrogenase/reductase family 628 10878 21128
Re01.g06370 Pc21g20680 protein Precursor 629 10879 21129
Re01.g06380 Zinc finger protein, putative 630 10880 21130
Homogentisate 1,2-dioxygenase,
Re01.g06390 putative 631 10881 21131
Re01.g06400 Carboxyl esterase 632 10882 21132
Re01.g06410 hypothetical protein 633 10883 21133
Re01.g06420 MFS transporter 634 10884 21134
Re01.g06430 Carboxylesterase, putative 635 10885 21135
Re01.g06440 Tetratricopeptide repeat protein 1 636 10886 21136
HAD superfamily hydrolase,
Re01.g06450 putative 637 10887 21137
Re01.g06460 hypothetical protein 638 10888 21138 Re01.g06470 hypothetical protein 639 10889 21 139 30840 32330
Re01.g06480 hypothetical protein 640 10890 21 140
Re01.g06490 Putative uncharacterized protein 641 10891 21 141
Nucleoporin NUP49/NSP49,
Re01.g06500 putative 642 10892 21 142
Alpha-ketoglutarate-dependent
Re01.g06510 taurine dioxygenase 643 10893 21 143
Re01.g06520 ARS-binding protein 1 644 10894 21 144
Re01.g06530 Putative uncharacterized protein 645 10895 21 145
Re01.g06540 Predicted protein 646 10896 21 146
Re01.g06550 Chaperonin, putative 647 10897 21 147
Re01.g06560 Endoglucanase, putative 648 10898 21 148 30841 32331
Re01.g06570 Putative uncharacterized protein 649 10899 21 149
Re01.g06580 Putative uncharacterized protein 650 10900 21 150 30842 32332
Re01.g06590 Putative uncharacterized protein 651 10901 21 151 30843 32333
Re01.g06600 Ubiquitin-protein ligase 652 10902 21 152 30844 32334
Re01.g06610 Uncharacterized protein 653 10903 21 153
Ubiquitin-like activating enzyme
Re01.g06620 (UlaA), putative 654 10904 21 154
Re01.g06630 Ribose 5-phosphate isomerase A 655 10905 21 155
Nuclear pore complex subunit,
Re01.g06640 putative 656 10906 21 156
Re01.g06650 ATP binding protein, putative 657 10907 21 157
Re01.g06660 Rpp14 family family 658 10908 21 158
ATP citrate lyase, subunit 1 ,
Re01.g06670 putative 659 10909 21 159
ATP citrate lyase subunit (Acl),
Re01.g06680 putative 660 10910 21 160
Re01.g06690 Alpha-L-rhamnosidase 661 1091 1 21 161 30845 32335
Re01.g06700 Uncharacterized protein 662 10912 21 162
Putative uncharacterized protein
Re01.g06710 Fragment 663 10913 21 163 30846 32336
DNA polymerase delta subunit 4,
Re01.g06720 putative 664 10914 21 164
Re01.g06730 Acetamidase 665 10915 21 165
Re01.g06740 Uncharacterized protein 666 10916 21 166
Re01.g06750 Uncharacterized protein 667 10917 21 167
Ubiquitin-like activating enzyme
Re01.g06760 (UbaB), putative 668 10918 21 168
Re01.g06770 Pc21 g20220 protein 669 10919 21 169
Re01.g06780 Putative uncharacterized protein 670 10920 21 170
Predicted tRNA-splicing
Re01.g06790 endonuclease subunit 671 10921 21 171
Re01.g06800 Uncharacterized protein 672 10922 21 172
Re01.g06810 Arrestin domain protein 673 10923 21 173
Peptidyl-prolyl cis-trans isomerase,
Re01.g06820 putative 674 10924 21 174 30847 32337
Re01.g06830 Zinc finger protein ZPR1 675 10925 21 175
Re01.g06840 Uncharacterized protein 676 10926 21 176 RNA lariat debranching enzyme,
Re01.g06850 putative 677 10927 21 177
Re01.g06860 Protein required for cell viability 678 10928 21 178
Re01.g06870 hypothetical protein 679 10929 21 179 30848 32338
Re01.g06880 Chitin deacetylase, putative 680 10930 21 180 30849 32339
Re01.g06890 Putative uncharacterized protein 681 10931 21 181
Vacuolar protein sorting protein
Re01.g06900 (VPS1 1), putative 682 10932 21 182
Re01.g06910 Uncharacterized protein 683 10933 21 183
Conserved leucine-rich repeat
Re01.g06920 protein 684 10934 21 184
Inositol hexaphosphate kinase
Re01.g06930 KCS1 , putative 685 10935 21 185
MFS monocarboxylic acid
Re01.g06940 transporter, putative 686 10936 21 186
Re01.g06950 Putative uncharacterized protein 687 10937 21 187
Re01.g06960 hypothetical protein 688 10938 21 188
Re01.g06970 Kinesin family protein 689 10939 21 189
Re01.g06980 Agmatinase, putative 690 10940 21 190 30850 32340
Re01.g06990 Putative uncharacterized protein 691 10941 21 191
Re01.g07000 Putative uncharacterized protein 692 10942 21 192
WD domain, G-beta repeat
Re01.g07010 containing protein 693 10943 21 193
Re01.g07020 Chorismate mutase 694 10944 21 194
Re01.g07030 Protein BCP1 695 10945 21 195
Re01.g07040 GMP synthase 696 10946 21 196
Re01.g07050 hypothetical protein 697 10947 21 197
Re01.g07060 hypothetical protein 698 10948 21 198
Alpha- 1 ,2-mannosyltransferase,
Re01.g07070 putative 699 10949 21 199 30851 32341
Re01.g07080 Putative uncharacterized protein 700 10950 21200
Re01.g07090 DUF1275 domain protein 701 10951 21201
Putative uncharacterized protein
Re01.g07100 Fragment 702 10952 21202
Re01.g071 10 Uncharacterized protein 703 10953 21203
Re01.g07120 Putative uncharacterized protein 704 10954 21204
Histidinol dehydrogenase
Re01.g07130 EC=1.1.1.23 705 10955 21205
Re01.g07140 Uncharacterized protein 706 10956 21206
Re01.g07150 hypothetical protein 707 10957 21207
Re01.g07160 Putative uncharacterized protein 708 10958 21208
Re01.g07170 hypothetical protein 709 10959 21209
Re01.g07180 hypothetical protein 710 10960 21210
Re01.g07190 hypothetical protein 71 1 10961 2121 1
Re01.g07200 WD domain, G-beta repeat protein 712 10962 21212
Endo-1 ,3(4)-beta-glucanase,
Re01.g07210 putative 713 10963 21213
Oxidoreductase, short chain
Re01.g07220 dehydrogenase/reductase family 714 10964 21214 30852 32342 Re01.g07230 Uncharacterized protein Fragment 715 10965 21215
Re01.g07240 Uncharacterized protein Fragment 716 10966 21216
Function: PIP of B. coagulans has
a higher activity toward small
Re01.g07250 peptides EC=3.4.1 1.5 717 10967 21217 30853 32343
Re01.g07260 Oligopeptide transporter 718 10968 21218
Re01.g07270 Putative uncharacterized protein 719 10969 21219
Re01.g07280 hypothetical protein 720 10970 21220
Re01.g07290 Putative uncharacterized protein 721 10971 21221
FAD-binding oxidoreductase,
Re01.g07300 putative 722 10972 21222 30854 32344
Re01.g07310 Short-chain dehydrogenase 723 10973 21223
Re01.g07320 Putative uncharacterized protein 724 10974 21224 30855 32345
Putative oligopeptide transporter 6
Re01.g07330 protein 725 10975 21225
Re01.g07340 Predicted protein 726 10976 21226
Re01.g07350 Pc21 g03120 protein Precursor 727 10977 21227 30856 32346
CCCH finger DNA binding protein,
Re01.g07360 putative 728 10978 21228
Re01.g07370 Uncharacterized protein 729 10979 21229
Re01.g07380 Putative uncharacterized protein 730 10980 21230
Re01.g07390 Putative uncharacterized protein 731 10981 21231
Re01.g07400 hypothetical protein 732 10982 21232 30857 32347
Re01.g07410 Putative uncharacterized protein 733 10983 21233
RNA polymerase II holoenzyme
Re01.g07420 cyclin-like subunit 734 10984 21234
Calcium dependent mitochondrial
Re01.g07430 carrier protein, putative 735 10985 21235
Re01.g07440 Uncharacterized protein Fragment 736 10986 21236
Gamma-tubulin complex
Re01.g07450 component GCP4, putative 737 10987 21237
Short chain
dehydrogenase/oxidoreductase,
Re01.g07460 putative 738 10988 21238 30858 32348
Re01.g07470 Uncharacterized protein 739 10989 21239
Re01.g07480 Putative uncharacterized protein 740 10990 21240
Re01.g07490 Putative uncharacterized protein 741 10991 21241
Hexokinase family protein XprF,
Re01.g07500 putative 742 10992 21242
Re01.g07510 hypothetical protein 743 10993 21243
Re01.g07520 Uncharacterized protein 744 10994 21244
Re01.g07530 Uncharacterized protein 745 10995 21245
Re01.g07540 Amine oxidase 746 10996 21246 30859 32349
Re01.g07550 Putative uncharacterized protein 747 10997 21247
Aldehyde dehydrogenase family
Re01.g07560 protein, putative 748 10998 21248
Re01.g07570 Putative uncharacterized protein 749 10999 21249
Re01.g07580 N-methyltransferase, putative 750 1 1000 21250
Re01.g07590 Putative uncharacterized protein 751 1 1001 21251 30860 32350 Pyruvate formate lyase activating
Re01.g07600 enzyme, putative 752 1 1002 21252 30861 32351
Re01.g07620 Uncharacterized protein 753 1 1003 21253 30862 32352
Re01.g07630 Uncharacterized protein 754 1 1004 21254
Sulfite reductase [NADPH] subunit
Re01.g07640 beta 755 1 1005 21255
Re01.g07650 Putative uncharacterized protein 756 1 1006 21256 30863 32353
Function: Rab6 of H. sapiens is
probably involved in vesicle traffic
Re01.g07660 targeting 757 1 1007 21257
Re01.g07670 Uncharacterized protein 758 1 1008 21258 30864 32354
Re01.g07680 Putative uncharacterized protein 759 1 1009 21259 30865 32355
Re01.g07690 DDHD domain protein 760 1 1010 21260
Re01.g07700 Uncharacterized protein 761 1 101 1 21261
Re01.g07710 FAD monooxygenase, putative 762 1 1012 21262 30866 32356
Re01.g07720 DUF866 domain protein 763 1 1013 21263
Re01.g07730 Putative uncharacterized protein 764 1 1014 21264
Re01.g07740 Putative uncharacterized protein 765 1 1015 21265
Re01.g07750 Putative uncharacterized protein 766 1 1016 21266
Re01.g07760 Pc21 g03020 protein 767 1 1017 21267
Re01.g07770 Rho GTPase Rho4, putative 768 1 1018 21268
Sphingosine-1 -phosphate
Re01.g07780 phosphohydrolase 769 1 1019 21269
Re01.g07790 Protease 770 1 1020 21270
Endo-1 ,3(4)-beta-glucanase,
Re01.g07800 putative 771 1 1021 21271 30867 32357
Re01.g07810 Putative uncharacterized protein 772 1 1022 21272
Re01.g07820 HIT finger domain protein 773 1 1023 21273
Re01.g07830 Putative uncharacterized protein 774 1 1024 21274
Re01.g07840 Putative uncharacterized protein 775 1 1025 21275
Re01.g07850 Uncharacterized protein 776 1 1026 21276
Re01.g07860 Uncharacterized protein 777 1 1027 21277
Re01.g07870 Citrate synthase EC=2.3.3.1 778 1 1028 21278
Re01.g07880 RNA annealing protein Yra1 779 1 1029 21279
Re01.g07890 SNF7 family protein 780 1 1030 21280
Hsp90 binding co-chaperone
Re01.g07900 (Sba1 ), putative 781 1 1031 21281
Re01.g07910 HET-C domain protein HetC 782 1 1032 21282 30868 32358
Re01.g07920 Putative uncharacterized protein 783 1 1033 21283
Re01.g07930 Alpha-galactosidase A 784 1 1034 21284 30869 32359
Phytanoyl-CoA dioxygenase family
Re01.g07940 protein 785 1 1035 21285
Re01.g07950 Uncharacterized protein 786 1 1036 21286
Re01.g07960 Predicted protein 787 1 1037 21287
Re01.g07970 Uncharacterized protein 788 1 1038 21288
Re01.g07980 Importin beta-5 subunit, putative 789 1 1039 21289
Mitotic spindle checkpoint protein
Re01.g07990 (Mad2B), putative 790 1 1040 21290
Re01.g08000 hypothetical protein 791 1 1041 21291 Re01.g08010 RING finger protein, putative 792 1 1042 21292
Re01.g08020 Uncharacterized protein 793 1 1043 21293
Re01.g08030 Uncharacterized protein 794 1 1044 21294
Re01.g08040 Vanadate resistance protein 795 1 1045 21295
Short chain
dehydrogenase/reductase family
Re01.g08050 oxidoreductase 796 1 1046 21296 30870 32360
Re01.g08060 Putative uncharacterized protein 797 1 1047 21297
Pepsin-type protease
Re01.g08070 EC=3.4.23.18 798 1 1048 21298 30871 32361
Cytosolic Fe-S cluster assembly
Re01.g08080 factor NBP35 799 1 1049 21299 30872 32362
Phosphatidylethanolamine N-
Re01.g08090 methyltransferase EC=2.1.1.17 800 1 1050 21300
Re01.g08100 3' exoribonuclease family protein 801 1 1051 21301
Re01.g081 10 Predicted protein 802 1 1052 21302
Re01.g08120 hypothetical protein 803 1 1053 21303
Re01.g08130 Uncharacterized protein 804 1 1054 21304
Prolyl-tRNA synthetase
Re01.g08140 EC=6.1.1.15 805 1 1055 21305
Re01.g08150 T-complex protein 1 subunit alpha 806 1 1056 21306
Re01.g08160 WD domain protein 807 1 1057 21307
rRNA biogenesis protein RRP5,
Re01.g08170 putative 808 1 1058 21308
Re01.g08180 Uncharacterized protein 809 1 1059 21309
Re01.g08190 Putative uncharacterized protein 810 1 1060 21310
Re01.g08200 Urease accessory protein UreD 81 1 1 1061 2131 1
Nuclear cohesin complex subunit
Re01.g08210 (Psc3), putative 812 1 1062 21312
Re01.g08220 Karyopherin alpha subunit 813 1 1063 21313
Re01.g08230 Uncharacterized protein 814 1 1064 21314
C-x8-C-x5-C-x3-H zinc finger
Re01.g08240 protein 815 1 1065 21315
Re01.g08250 Uncharacterized protein 816 1 1066 21316 30873 32363
Re01.g08260 Putative uncharacterized protein 817 1 1067 21317
Re01.g08270 DEAD/DEAH box helicase, putative 818 1 1068 21318
G2/mitotic-specific cyclin (Clb3),
Re01.g08280 putative 819 1 1069 21319
Re01.g08290 C6 finger domain protein, putative 820 1 1070 21320
DNA-directed RNA polymerase III
Re01.g08300 RPC4, putative 821 1 1071 21321
Re01.g08310 Uncharacterized protein 822 1 1072 21322 30874 32364
Re01.g08320 Putative uncharacterized protein 823 1 1073 21323
Chromosome condensation protein
Re01.g08330 (CrcB), putative 824 1 1074 21324
Re01.g08340 Uracil phosphoribosyltransferase 825 1 1075 21325
Re01.g08350 Function: AmdA 826 1 1076 21326
Re01.g08360 Putative uncharacterized protein 827 1 1077 21327
Re01.g08370 Cell division control protein Cdc25 828 1 1078 21328 C0P9 signalosome complex
Re01.g08380 subunit 5 829 11079 21329
Microtubule associated protein
Re01.g08390 (Ase1), putative 830 11080 21330
Re01.g08400 Glutamyl-tRNA synthetase 831 11081 21331
DnaJ domain protein (Mas5),
Re01.g08410 putative 832 11082 21332
Re01.g08420 Predicted protein 833 11083 21333
Dihydroxy acid dehydratase,
Re01.g08430 putative EC=4.2.1.9 834 11084 21334
Re01.g08440 Putative uncharacterized protein 835 11085 21335
Re01.g08450 Thioesterase family protein 836 11086 21336
Re01.g08460 Pseudouridine synthase 837 11087 21337
Re01.g08470 60S ribosomal protein L32 838 11088 21338
NAD-binding Rossmann fold
Re01.g08480 oxidoreductase family protein 839 11089 21339
Sister chromatid cohesion and
Re01.g08490 DNA repair protein (BimD), putative 840 11090 21340
Putative uncharacterized protein
Re01.g08500 An03g00600 841 11091 21341
Re01.g08510 SWI-SNF complex subunit 842 11092 21342
Endonuclease/exonuclease/phosp
Re01.g08520 hatase family protein 843 11093 21343 30875 32365
Re01.g08530 Curved DNA-binding protein 844 11094 21344
PHD finger domain protein,
Re01.g08540 putative 845 11095 21345
Lectin family integral membrane
Re01.g08550 protein, putative 846 11096 21346 30876 32366
Re01.g08560 Putative uncharacterized protein 847 11097 21347 30877 32367
Re01.g08570 hypothetical protein 848 11098 21348
Re01.g08580 DDT domain protein 849 11099 21349
Mitochondrial carrier protein
Re01.g08590 (Leu5), putative 850 11100 21350
Re01.g08600 hypothetical protein 851 11101 21351
Re01.g08610 Putative uncharacterized protein 852 11102 21352
60S ribosomal export protein
Re01.g08620 NMD3 853 11103 21353
Re01.g08630 Uncharacterized protein 854 11104 21354
Peroxisome biosynthesis protein
Re01.g08640 (PAS10/Peroxin-12), putative 855 11105 21355
Re01.g08660 Uncharacterized protein 856 11106 21356
Postreplication repair E3 ubiquitin-
Re01.g08670 protein ligase rad18 857 11107 21357
Vacuolar sorting protein SNF7
Re01.g08680 family protein, putative 858 11108 21358
Re01.g08690 Uncharacterized protein 859 11109 21359 30878 32368
Function: M. grisea Pth11 is a
Re01.g08700 pathogenicity gene Precursor 860 11110 21360
Putative uncharacterized protein
Re01.g08710 Fragment 861 11111 21361 Re01.g08720 Uncharacterized protein 862 11112 21362
Remark: the multifunctional
Re01.g08730 polyketide synthase 863 11113 21363
Re01.g08740 RTA1 domain protein 864 11114 21364
MOSC domain-containing protein
Re01.g08750 1, mitochondrial 865 11115 21365
Re01.g08760 Putative uncharacterized protein 866 11116 21366
Re01.g08770 Putative uncharacterized protein 867 11117 21367
Re01.g08780 Uncharacterized protein 868 11118 21368
Re01.g08790 hypothetical protein 869 11119 21369
Re01.g08800 Uncharacterized protein 870 11120 21370
Re01.g08810 GPI anchored cell wall protein 871 11121 21371 30879 32369
Re01.g08820 Allantoicase Ale, putative 872 11122 21372
Re01.g08830 hypothetical protein 873 11123 21373
Re01.g08840 hypothetical protein 874 11124 21374
Re01.g08850 Uncharacterized protein 875 11125 21375
ATP :tRNA-specific tRNA
Re01.g08860 nucleotidyltransferase 876 11126 21376
Polyphosphoinositide phosphatase
Re01.g08870 Fig4 877 11127 21377
Re01.g08880 Acyl-CoA dehydrogenase 878 11128 21378
Re01.g08890 hypothetical protein 879 11129 21379
Re01.g08900 Protein kinase, putative 880 11130 21380
Re01.g08910 C6 transcription factor, putative 881 11131 21381
Re01.g08920 DNA polymerase EC=2.7.7.7 882 11132 21382
Re01.g08930 Putative uncharacterized protein 883 11133 21383
Re01.g08940 hypothetical protein 884 11134 21384
Re01.g08950 Uncharacterized protein 885 11135 21385
Re01.g08960 Uncharacterized protein 886 11136 21386
Re01.g08970 Uncharacterized protein 887 11137 21387
Re01.g08980 Putative uncharacterized protein 888 11138 21388
Re01.g08990 hypothetical protein 889 11139 21389
Re01.g09000 Uncharacterized protein 890 11140 21390
Re01.g09010 hypothetical protein 891 11141 21391
Re01.g09020 Putative uncharacterized protein 892 11142 21392
C2H2 finger domain protein,
Re01.g09030 putative 893 11143 21393
Re01.g09040 Cyanate hydratase EC=4.2.1.104 894 11144 21394
Re01.g09050 Putative uncharacterized protein 895 11145 21395
Re01.g09060 Uncharacterized protein 896 11146 21396
Whole genome shotgun sequence
Re01.g09070 assembly, scaffold_4, strain Mel28 897 11147 21397
Re01.g09080 Transposase 898 11148 21398
Re01.g09090 Predicted protein 899 11149 21399
DHHC zinc finger membrane
Re01.g09100 protein 900 11150 21400
Re01.g09110 Palmitoyltransferase EC=2.3.1.- 901 11151 21401
Re01.g09130 hypothetical protein 902 11152 21402 30880 32370
Re01.g09140 Ubiquitin conjugating enzyme 903 11153 21403 (UbcF), putative
TFIIIC transcription initiation factor
Re01.g09150 complex subunits Tfc3 904 11154 21404
Re01.g09160 Uncharacterized protein 905 11155 21405
Similarity to hypothetical protein
Re01.g09170 encoded by An06g02540 906 11156 21406
Re01.g09180 Putative uncharacterized protein 907 11157 21407
Re01.g09190 Putative uncharacterized protein 908 11158 21408
Re01.g09200 Putative uncharacterized protein 909 11159 21409
Re01.g09210 Translation initiation factor 4B 910 11160 21410
Re01.g09220 Putative uncharacterized protein 911 11161 21411
Re01.g09230 Uncharacterized protein 912 11162 21412
Re01.g09240 Heme-binding peroxidase 913 11163 21413
Re01.g09250 MFS multidrug transporter, putative 914 11164 21414
Re01.g09260 hypothetical protein 915 11165 21415
Re01.g09270 Putative uncharacterized protein 916 11166 21416
PHD and RING finger domain
protein, putative (AFU orthologue;
Re01.g09280 AFUA_2G16870) 917 11167 21417
Re01.g09290 Putative uncharacterized protein 918 11168 21418
Re01.g09300 Uncharacterized protein 919 11169 21419
RNA export mediator Gle1 ,
Re01.g09310 putative 920 11170 21420
Cell wall biogenesis protein
Re01.g09320 phosphatase Ssd1 , putative 921 11171 21421
Ubiquitin conjugating enzyme E2,
Re01.g09330 putative 922 11172 21422
Re01.g09340 hypothetical protein 923 11173 21423 30881 32371
Re01.g09350 hypothetical protein 924 11174 21424
Re01.g09360 Uncharacterized protein 925 11175 21425 30882 32372
Re01.g09370 Elongation factor 1-beta 926 11176 21426
Heat shock protein/chaperonin
Re01.g09380 HSP78, putative 927 11177 21427
DNA mismatch repair protein
Re01.g09390 Msh5, putative 928 11178 21428
Re01.g09400 Putative uncharacterized protein 929 11179 21429
Fungal transcriptional regulatory
Re01.g09410 protein 930 11180 21430
Re01.g09420 Glycerol dehydrogenase 931 11181 21431
Re01.g09430 Putative uncharacterized protein 932 11182 21432
3-ketosphinganine reductase
Re01.g09440 (TsdO), putative 933 11183 21433
Re01.g09450 Sterol desaturase family 934 11184 21434
Re01.g09460 60S ribosomal protein L6 935 11185 21435
Re01.g09470 Uncharacterized protein 936 11186 21436
Re01.g09480 Calcium channel subunit Cch1 937 11187 21437
Re01.g09490 Putative uncharacterized protein 938 11188 21438
Gag/polymerase/env polyprotein,
Re01.g09500 putative 939 11189 21439 Histone H3 methyltransferase
Re01.g09510 SUV39H1/Clr4 Fragment 940 1 1 190 21440
Re01.g09520 Uncharacterized protein 941 1 1 191 21441
Serine/threonine protein kinase
Re01.g09530 Kin1 , putative 942 1 1 192 21442
Re01.g09540 G-patch domain protein, putative 943 1 1 193 21443
Re01.g09550 Ubiquitin domain protein, putative 944 1 1 194 21444
Ribosomal RNA processing
Re01.g09560 protein, putative 945 1 1 195 21445
Re01.g09570 Uncharacterized protein 946 1 1 196 21446
Re01.g09580 Coatomer subunit beta 947 1 1 197 21447
Re01.g09590 Mago nashi domain protein 948 1 1 198 21448
Vesicle-mediated transport protein
Re01.g09600 Vid24 949 1 1 199 21449
MAP kinase kinase kinase SskB,
Re01.g09610 putative EC=2.7.1 1.25 950 1 1200 21450
Ammonium transporter (Mep2),
Re01.g09620 putative 951 1 1201 21451
Nuclear mRNA splicing factor-
Re01.g09630 associated protein, putative 952 1 1202 21452
Beta-1 and beta-2 tubulin
Re01.g09640 Fragment 953 1 1203 21453
Re01.g09650 Putative uncharacterized protein 954 1 1204 21454
Re01.g09660 Purine-cytosine permease, putative 955 1 1205 21455
P-type calcium ATPase, putative
Re01.g09670 EC=3.6.3.8 956 1 1206 21456
Cyanamide hydratase family HD
Re01.g09680 domain-containing protein 957 1 1207 21457
Nuclear pore complex protein
Re01.g09690 Nup107 958 1 1208 21458
Ubiquitin-like modifier SUMO,
Re01.g09700 putative 959 1 1209 21459 30883 32373
Re01.g09710 Uncharacterized protein 960 1 1210 21460
Re01.g09720 CoA-ligase 961 1 121 1 21461
Putative uncharacterized protein
Re01.g09730 Fragment 962 1 1212 21462
Vacuolar ATP synthase subunit c
Re01.g09740 EC=3.6.3.14 963 1 1213 21463
Adenylyl-sulfate kinase
Re01.g09750 EC=2.7.1.25 964 1 1214 21464
Re01.g09760 Uncharacterized protein 965 1 1215 21465
Re01.g09770 hypothetical protein 966 1 1216 21466 30884 32374
Re01.g09780 hypothetical protein 967 1 1217 21467
Re01.g09790 MFS multidrug transporter, putative 968 1 1218 21468
Aminomethyltransferase
Re01.g09800 EC=2.1.2.10 969 1 1219 21469 30885 32375
Neutral amino acid permease,
Re01.g09810 putative 970 1 1220 21470
CCAAT-box-binding transcription
Re01.g09820 factor 971 1 1221 21471 Re01.g09830 Prolyl-tRNA synthetase 972 1 1222 21472
Re01.g09840 Prefoldin subunit 5, putative 973 1 1223 21473
Re01.g09850 Similar to An08g02820 974 1 1224 21474
Origin recognition complex subunit
Re01.g09860 Orel , putative 975 1 1225 21475
mRNA splicing protein (Prp5),
Re01.g09870 putative 976 1 1226 21476
Proteasome regulatory particle
Re01.g09880 subunit (Nas6), putative 977 1 1227 21477
Re01.g09890 M protein repeat protein 978 1 1228 21478
Re01.g09900 Vacuolar ATP synthase subunit H 979 1 1229 21479
Re01.g09910 Predicted protein 980 1 1230 21480
Re01.g09920 Putative uncharacterized protein 981 1 1231 21481
Re01.g09930 hypothetical protein 982 1 1232 21482
Re01.g09940 Putative uncharacterized protein 983 1 1233 21483
Re01.g09950 Uncharacterized protein 984 1 1234 21484
Re01.g09960 Transposase 985 1 1235 21485
Re01.g09970 Putative uncharacterized protein 986 1 1236 21486 30886 32376
Re01.g09980 Ferric-chelate reductase 987 1 1237 21487 30887 32377
Re01.g09990 Putative uncharacterized protein 988 1 1238 21488
Re01.g10000 ATP binding protein, putative 989 1 1239 21489
S-adenosylmethionine synthase
Re01.g10010 EC=2.5.1.6 990 1 1240 21490
Re01.g10020 Uncharacterized protein 991 1 1241 21491
Re01.g10030 hypothetical protein 992 1 1242 21492
Re01.g10040 Nuclear localization protein 993 1 1243 21493
Re01.g10050 GPI anchored protein, putative 994 1 1244 21494 30888 32378
Re01.g10060 Uncharacterized protein 995 1 1245 21495
Re01.g10070 Glycerol-3-phosphate phosphatase 996 1 1246 21496
Re01.g10080 GTP binding protein, putative 997 1 1247 21497
Re01.g10090 Uncharacterized protein 998 1 1248 21498
SIR2 family histone deacetylase
Re01.g10100 (Hst4), putative 999 1 1249 21499
Re01.g101 10 Uncharacterized protein 1000 1 1250 21500
Re01.g10120 60S ribosomal protein L35, putative 1001 1 1251 21501
Golgi SNAP receptor complex
Re01.g10130 member 1 1002 1 1252 21502
F1 FO ATP synthase assembly
Re01.g10140 protein Atp10, putative 1003 1 1253 21503
Re01.g10150 DNA polymerase POL4, putative 1004 1 1254 21504
Re01.g10160 Uncharacterized protein 1005 1 1255 21505
Re01.g10170 Putative uncharacterized protein 1006 1 1256 21506
Re01.g10180 Uncharacterized protein 1007 1 1257 21507
Re01.g10190 Hyaluronidase EC=3.2.1.35 1008 1 1258 21508
Re01.g10200 Putative uncharacterized protein 1009 1 1259 21509
Re01.g10210 Putative uncharacterized protein 1010 1 1260 21510
Re01.g10220 Predicted protein 101 1 1 1261 2151 1
DNA repair protein RAD51 ,
Re01.g10230 putative 1012 1 1262 21512 Re01■9' 0240 Uncharacterized protein 1013 1 1263 21513
Re01 ■g' 0250 MSF drug transporter, putative 1014 1 1264 21514
Mitochondrial outer membrane
Re01 ■g' 0260 protein iml2 1015 1 1265 21515
Re01 ■g' 0270 hypothetical protein 1016 1 1266 21516
Phosphoglycerate kinase
Re01 ■g' 0280 EC=2.7.2.3 1017 1 1267 21517
Re01 ■g' 0290 Putative uncharacterized protein 1018 1 1268 21518
Re01 ■g' 0300 Putative uncharacterized protein 1019 1 1269 21519
Re01 ■g' 0310 Putative uncharacterized protein 1020 1 1270 21520
RNase L inhibitor of the ABC
Re01 ■g' 0320 superfamily 1021 1 1271 21521
Re01 ■g' 0330 Chromodomain helicase 1022 1 1272 21522
C2H2 finger domain protein (Gli3),
Re01 ■g' 0340 putative 1023 1 1273 21523
Pyridoxal reductase (AKR8),
Re01 ■g' 0350 putative 1024 1 1274 21524
Re01 ■g' 0360 hypothetical protein 1025 1 1275 21525 30889 32379
Re01 ■g' 0370 MFS multidrug transporter, putative 1026 1 1276 21526
Re01 ■g' 0380 Uncharacterized protein 1027 1 1277 21527
Re01 ■g' 0390 TIM-barrel enzyme family protein 1028 1 1278 21528
Re01 ■g' 0400 hypothetical protein 1029 1 1279 21529
Re01 ■g' 0410 Predicted protein 1030 1 1280 21530
Re01 ■g' 0420 UPF0261 domain protein 1031 1 1281 21531
Re01 ■g' 0430 Putative uncharacterized protein 1032 1 1282 21532
Re01 ■g' 0440 Putative hydrolase 1033 1 1283 21533
Adenosylhomocysteinase
Re01 ■g' 0450 EC=3.3.1.1 1034 1 1284 21534
GNAT family acetyltransferase,
Re01 ■g' 0460 putative 1035 1 1285 21535
Re01 ■g' 0470 Putative uncharacterized protein 1036 1 1286 21536
Pre-mRNA splicing factor (Prp31 ),
Re01 ■g' 0480 putative 1037 1 1287 21537
Cell cycle control protein (Cwf4),
Re01 ■g' 0490 putative 1038 1 1288 21538
Re01 ■g' 0500 Uncharacterized protein 1039 1 1289 21539
C2H2 transcription factor (Egr2),
putative (AFU orthologue
Re01 ■g' 0510 AFUAJ G10230) 1040 1 1290 21540
Re01 ■g' 0520 Putative uncharacterized protein 1041 1 1291 21541
Re01 ■g' 0530 Putative uncharacterized protein 1042 1 1292 21542
3-hydroxyisobutyrate
Re01 ■g' 0540 dehydrogenase, putative 1043 1 1293 21543
Re01 ■g' 0550 Alcohol dehydrogenase, putative 1044 1 1294 21544
Early growth response protein,
Re01 ■g' 0560 putative 1045 1 1295 21545
4-carboxymuconolactone
Re01 ■g' 0570 decarboxylase, putative 1046 1 1296 21546
Re01 ■g' 0580 3-hydroxyisobutyrate 1047 1 1297 21547 dehydrogenase, putative
Re01.g10590 Uncharacterized protein 1048 1 1298 21548 30890 32380
Re01.g10600 Uncharacterized protein 1049 1 1299 21549
High-affinity nicotinic acid
Re01.g10610 transporter, putative 1050 1 1300 21550
Re01.g10620 Putative uncharacterized protein 1051 1 1301 21551
Re01.g10630 Laccase, putative 1052 1 1302 21552 30891 32381
Re01.g10640 Pc16g1 1620 protein Precursor 1053 1 1303 21553
Re01.g10650 hypothetical protein 1054 1 1304 21554
Putative carbohydrate
Re01.g10660 acetylesterase 1055 1 1305 21555 30892 32382
Re01.g10670 Putative uncharacterized protein 1056 1 1306 21556
3-oxoacyl-(Acyl-carrier-protein)
Re01.g10680 reductase 1057 1 1307 21557
Re01.g10690 hypothetical protein 1058 1 1308 21558
Re01.g10700 Multicopper oxidase 1059 1 1309 21559 30893 32383
Re01.g10710 Predicted protein 1060 1 1310 21560 30894 32384
Re01.g10720 Uncharacterized protein 1061 1 131 1 21561
Re01.g10730 C2H2 transcription factor, putative 1062 1 1312 21562
Pre-mRNA-processing ATP- dependent RNA helicase prp5
Re01.g10740 EC=3.6.4.13 1063 1 1313 21563
Probable alpha-N- arabinofuranosidase C
Re01.g10750 EC=3.2.1.55 Precursor 1064 1 1314 21564
Re01.g10760 MFS sugar transporter, putative 1065 1 1315 21565
Re01.g10770 Putative uncharacterized protein 1066 1 1316 21566
Glycerol dehydrogenase Gcy1 ,
Re01.g10780 putative 1067 1 1317 21567
Re01.g10790 Putative uncharacterized protein 1068 1 1318 21568
Casein kinase 2 beta' regulatory
Re01.g10800 subunit Ckb2, putative 1069 1 1319 21569
Kynurenine formamidase
Re01.g10810 EC=3.5.1.9 1070 1 1320 21570
Eukaryotic translation initiation
Re01.g10820 factor 3 subunit H 1071 1 1321 21571
Mitochondrial carrier protein,
Re01.g10830 putative 1072 1 1322 21572
Re01.g10840 BTB/POZ domain protein 1073 1 1323 21573
Re01.g10850 Uncharacterized protein 1074 1 1324 21574
Re01.g10860 Putative uncharacterized protein 1075 1 1325 21575
Re01.g10870 BTB/POZ domain protein 1076 1 1326 21576
Re01.g10880 Putative uncharacterized protein 1077 1 1327 21577
Re01.g10890 Putative uncharacterized protein 1078 1 1328 21578
Re01.g10900 Uncharacterized protein 1079 1 1329 21579
Re01.g10910 hypothetical protein 1080 1 1330 21580
Re01.g10920 Uncharacterized protein 1081 1 1331 21581
Re01.g10930 hypothetical protein 1082 1 1332 21582
Re01.g10940 Uncharacterized protein 1083 1 1333 21583 Re01.g10950 Putative uncharacterized protein 1084 11334 21584
Re01.g10960 Uncharacterized protein Fragment 1085 11335 21585
Re01.g10970 Putative uncharacterized protein 1086 11336 21586
Re01.g10980 Pc20g 13930 protein 1087 11337 21587
Re01.g10990 HMG box protein, putative 1088 11338 21588
Re01.g11000 Uncharacterized protein 1089 11339 21589 30895 32385
Phytanoyl-CoA dioxygenase family
Re01.g11010 protein 1090 11340 21590
Re01.g11020 Uncharacterized protein 1091 11341 21591
Re01.g11030 Uncharacterized protein 1092 11342 21592
Re01.g11040 Uncharacterized protein 1093 11343 21593
[NiFe]-hydrogenase-3-type
complex, small
subunit/NADH:quinone
Re01.g11050 oxidoreductase, subunit NuoB 1094 11344 21594
Re01.g11060 hypothetical protein 1095 11345 21595 30896 32386
Re01.g11070 VPS9 domain protein 1096 11346 21596 30897 32387
37S ribosomal protein S11 ,
Re01.g11080 putative 1097 11347 21597 30898 32388
Putative uncharacterized protein
Re01.g11090 An08g01650 1098 11348 21598
Hsc70 cochaperone (SGT),
Re01.g11100 putative 1099 11349 21599
Re01.g11110 DUF1339 domain protein 1100 11350 21600
Re01.g11120 Predicted protein 1101 11351 21601
Re01.g11130 Putative uncharacterized protein 1102 11352 21602
Re01.g11140 Predicted protein 1103 11353 21603
Re01.g11150 Predicted protein 1104 11354 21604
Re01.g11160 Glycerol uptake facilitator, putative 1105 11355 21605
Re01.g11170 hypothetical protein 1106 11356 21606
Re01.g11180 Reverse transcriptase, putative 1107 11357 21607
Similar to MFS monocarboxylate
Re01.g11190 transporter 1108 11358 21608
PUA RNA binding domain protein,
Re01.g11200 putative 1109 11359 21609
Re01.g11210 GTP-binding protein YchF 1110 11360 21610
Re01.g11220 Pc13g01350 protein Precursor 1111 11361 21611 30899 32389
Re01.g11230 Thioesterase domain protein 1112 11362 21612
Re01.g11240 hypothetical protein 1113 11363 21613
Histone transcription regulator Hir1 ,
Re01.g11250 putative 1114 11364 21614
Re01.g11260 Stomatin family protein 1115 11365 21615
Re01.g11270 Putative uncharacterized protein 1116 11366 21616
Re01.g11280 Protein rmd11 1117 11367 21617 30900 32390
Re01.g11290 Predicted protein 1118 11368 21618
Re01.g11300 DUF636 domain protein 1119 11369 21619
Re01.g11310 Predicted protein 1120 11370 21620
Uncharacterized protein conserved
Re01.g11320 in bacteria 1121 11371 21621 3-oxoacyl-(Acyl-carrier-protein)
Re01.g11330 reductase EC=1.1.1.100 1122 11372 21622
Aldehyde reductase (AKR1),
Re01 ■gi 1340 putative 1123 11373 21623
Re01 ■gi 1350 PAP2 domain protein 1124 11374 21624
Re01 ■gi 1360 Putative uncharacterized protein 1125 11375 21625
Re01 ■gi 1370 Ankyrin repeat protein 1126 11376 21626
Re01 ■gi 1380 tRNA ligase 1127 11377 21627
Re01 ■gi 1390 Golgi traffic protein SFT2, putative 1128 11378 21628
Re01 ■gi 1400 hypothetical protein 1129 11379 21629
Re01 ■gi 1410 Uncharacterized protein 1130 11380 21630
Efflux pump antibiotic resistance
Re01 ■gi 1420 protein, putative 1131 11381 21631
Re01 ■gi 1430 hypothetical protein 1132 11382 21632
Mitochondrial 2-oxodicarboxylate
Re01 ■gi 1440 carrier 1 , putative 1133 11383 21633
Re01 ■gi 1450 Pc16g03370 protein Precursor 1134 11384 21634 30901 32391
Re01 ■gi 1460 Uncharacterized protein 1135 11385 21635
Re01 ■gi 1470 Actin-interacting protein 1136 11386 21636
Re01 ■gi 1480 Uncharacterized protein 1137 11387 21637
PAB1 binding protein (Pbp1),
Re01 ■gi 1490 putative 1138 11388 21638
Re01 ■gi 1500 Protein kinase family protein 1139 11389 21639
Re01 ■gi 1510 Putative uncharacterized protein 1140 11390 21640
Re01 ■gi 1520 Uncharacterized protein 1141 11391 21641
Re01 ■gi 1530 Putative uncharacterized protein 1142 11392 21642 30902 32392
N-acetyltransferase complex ARD1
Re01 ■gi 1540 subunit, putative 1143 11393 21643
Re01 ■gi 1550 hypothetical protein 1144 11394 21644
Re01 ■gi 1560 Putative uncharacterized protein 1145 11395 21645
Putative uncharacterized protein
Re01 ■gi 1570 An08g01140 EC=3.6.4.2 1146 11396 21646
Re01 ■gi 1580 Vacuolar transporter chaperone 1 1147 11397 21647
Re01 ■gi 1590 Methyltransferase, putative 1148 11398 21648
Re01 ■gi 1600 Uncharacterized protein 1149 11399 21649
Re01 ■gi 1610 Putative uncharacterized protein 1150 11400 21650
Re01 ■gi 1620 Deoxyribose-phosphate aldolase 1151 11401 21651
GPI anchored serine-threonine rich
Re01 ■gi 1630 protein 1152 11402 21652 30903 32393
Putative e3 ubiquitin-protein ligase
Re01 ■gi 1640 hula protein 1153 11403 21653
Re01 ■gi 1650 Polyadenylate-binding protein 1154 11404 21654
Vacuolar protein sorting 29,
Re01 ■gi 1660 putative 1155 11405 21655
Re01 ■gi 1670 Aminotransferase, class V, putative 1156 11406 21656
Re01 ■gi 1680 NIF domain protein 1157 11407 21657
Re01 ■gi 1690 Translation regulator GCD7 1158 11408 21658
Ribosomal protein of the small
Re01.g11700 subunit rps28-Aspergillus niger 1159 11409 21659 Re01■g' 1710 Putative uncharacterized protein 1160 11410 21660
Re01 ■g' 1720 Putative uncharacterized protein 1161 11411 21661 30904 32394
Re01 ■g' 1730 50S ribosomal protein L17 1162 11412 21662
Re01 ■g' 1740 R3H domain protein 1163 11413 21663
Re01 ■g' 1750 Putative uncharacterized protein 1164 11414 21664
Putative uncharacterized protein
Re01 ■g' 1760 Fragment 1165 11415 21665
Re01 ■g' 1770 Uncharacterized protein 1166 11416 21666
Complex: S. cerevisiae TFIID is
Re01 ■g' 1780 composed of TBP 1167 11417 21667
Eukaryotic translation initiation
Re01 ■g' 1800 factor 3 subunit F 1168 11418 21668
U3 small nucleolar RNA-associated
Re01 ■g' 1810 protein 25 1169 11419 21669
Re01 ■g' 1820 DUF6 domain protein, putative 1170 11420 21670
Re01 ■g' 1830 Uncharacterized protein 1171 11421 21671
Re01 ■g' 1840 Uncharacterized protein 1172 11422 21672
Cholinephosphate
Re01 ■g' 1850 cytidylyltransferase , putative 1173 11423 21673
Protein phosphatase 2C, putative
Re01 ■g' 1860 EC=3.1.3.16 1174 11424 21674
Transmembrane glycoprotein,
Re01 ■g' 1870 putative 1175 11425 21675 30905 32395
Acetyltransferase, GNAT family
Re01 ■g' 1880 family 1176 11426 21676
Re01 ■g' 1890 CUE domain protein, putative 1177 11427 21677
Re01 ■g' 1900 Putative uncharacterized protein 1178 11428 21678
Re01 ■g' 1910 Putative uncharacterized protein 1179 11429 21679
Re01 ■g' 1920 Putative uncharacterized protein 1180 11430 21680
AAA family ATPase/60S ribosome
Re01 ■g' 1930 export protein Rix7, putative 1181 11431 21681
Re01 ■g' 1940 Ribosome biogenesis protein erbl 1182 11432 21682
Arginine/serine-rich splicing factor,
Re01 ■g' 1950 putative 1183 11433 21683
Re01 ■g' 1960 Uncharacterized protein 1184 11434 21684
Re01 ■g' 1970 Acetamidase 1185 11435 21685
Re01 ■g' 1980 Uncharacterized protein 1186 11436 21686
Golgi transport complex
Re01 ■g' 1990 component Cog5, putative 1187 11437 21687
Re01 ■g' 2000 hypothetical protein 1188 11438 21688
Re01 ■g' 2010 C2H2 transcription factor, putative 1189 11439 21689
Re01 ■g' 2020 Putative uncharacterized protein 1190 11440 21690 30906 32396
Re01 ■g' 2030 Uncharacterized protein 1191 11441 21691
DNA mismatch repair protein
Re01 ■g' 2040 Msh2, putative 1192 11442 21692
N-acetylglucosaminyltransferase
Re01 ■g' 2050 complex, subunit PIG-Q/GPI1 1193 11443 21693
Re01 ■g' 2060 Uncharacterized protein 1194 11444 21694
Re01 ■g' 2070 Putative uncharacterized protein 1195 11445 21695 Mitochondrial distribution and
Re01 ■g 2080 morphology protein, putative 1196 11446 21696
Re01 ■g 2090 hypothetical protein 1197 11447 21697
MFS monocarboxylate transporter,
Re01 ■g 2100 putative 1198 11448 21698
GTPase activating protein Sari ,
Re01 ■g 2110 putative 1199 11449 21699
Re01 ■g 2120 hypothetical protein 1200 11450 21700
Phosphatidylinositol transporter,
Re01 ■g 2130 putative 1201 11451 21701
Re01 ■g 2140 Uncharacterized protein 1202 11452 21702
Re01 ■g 2150 Putative uncharacterized protein 1203 11453 21703
Re01 ■g 2160 Putative uncharacterized protein 1204 11454 21704
Re01 ■g 2170 Uncharacterized protein 1205 11455 21705
Phospholipid:diacylglycerol
Re01 ■g 2180 acyltransferase, putative 1206 11456 21706
Aureobasidin resistance protein
Re01 ■g 2190 Aur1 1207 11457 21707
Re01 ■g 2200 hypothetical protein 1208 11458 21708
Re01 ■g 2210 Uncharacterized protein 1209 11459 21709
Vacuolar iron transporter Ccc1 ,
Re01 ■g 2220 putative 1210 11460 21710
Phosphatidylglycerol specific
Re01 ■g 2230 phospholipase 1211 11461 21711 30907 32397
Re01 ■g 2240 Pc12g15490 protein Precursor 1212 11462 21712 30908 32398
Re01 ■g 2250 hypothetical protein 1213 11463 21713 30909 32399
Re01 ■g 2260 Predicted protein 1214 11464 21714
Re01 ■g 2270 hypothetical protein 1215 11465 21715
Re01 ■g 2280 Uncharacterized protein Fragment 1216 11466 21716
Re01 ■g 2290 Putative uncharacterized protein 1217 11467 21717
cAMP-dependent protein kinase
Re01 ■g 2300 regulatory subunit 1218 11468 21718
Re01 ■g 2310 Putative uncharacterized protein 1219 11469 21719
Re01 ■g 2320 Cytochrome P450, putative 1220 11470 21720 30910 32400
Re01 ■g 2330 Putative uncharacterized protein 1221 11471 21721
Re01 ■g 2340 Forkhead domain protein 1222 11472 21722
Re01 ■g 2350 CTP synthase EC=6.3.4.2 1223 11473 21723
Re01 ■g 2360 Vacuolar-sorting protein SNF7 1224 11474 21724
Re01 ■g 2370 Putative uncharacterized protein 1225 11475 21725
Re01 ■g 2380 MFS multidrug transporter 1226 11476 21726
Glucose-methanol-choline (Gmc)
Re01 ■g 2390 oxidoreductase, putative 1227 11477 21727
Re01 ■g 2400 hypothetical protein 1228 11478 21728
Re01 ■g 2410 BCAS2 family protein 1229 11479 21729
Neutral/alkaline nonlysosomal
Re01 ■g 2420 ceramidase, putative 1230 11480 21730 30911 32401
Autotransporter-associated beta
Re01 ■g 2430 strand repeat protein Precursor 1231 11481 21731 30912 32402
Re01 ■g 2440 Zn(ll)2Cys6 transcription factor 1232 11482 21732 Re01.g 12450 Putative uncharacterized protein 1233 11483 21733
Re01 .g 12460 Haloacid dehalogenase, type II 1234 11484 21734
Re01 .g 12470 Uncharacterized protein 1235 11485 21735
Re01 .g 12480 Putative uncharacterized protein 1236 11486 21736
Re01 .g 12490 Elongation factor Tu 1237 11487 21737 30913 32403
Mitochondrial carrier protein
Re01 .g12500 (Ymd), putative 1238 11488 21738
Re01 .g12510 Predicted protein 1239 11489 21739
Re01 .g 12520 Uncharacterized protein 1240 11490 21740
Neutral alpha-glucosidase ab
(Glucosidase II alpha subunit)
Re01 .g12530 (Alpha glucosidase 2) 1241 11491 21741
Re01 .g 12540 40S ribosomal protein S2 1242 11492 21742
Re01 .g 12550 37S ribosomal protein MRP4 1243 11493 21743
60S ribosome biogenesis protein
Re01 .g 12560 Rrp14, putative 1244 11494 21744
NADH-quinone oxidoreductase, 23
Re01 .g12570 kDa subunit, putative EC=1.6.99.3 1245 11495 21745 30914 32404
Vacuolar protein sorting-associated
Re01 .g12580 protein 1246 11496 21746
Zinc-binding oxidoreductase,
Re01 .g12590 putative 1247 11497 21747
Re01 .g12600 hypothetical protein 1248 11498 21748
Re01 .g12610 hypothetical protein 1249 11499 21749
Re01 .g 12620 Putative uncharacterized protein 1250 11500 21750
Re01 .g12630 CBS domain protein 1251 11501 21751
Re01 .g 12640 hypothetical protein 1252 11502 21752
Re01 .g 12650 Putative uncharacterized protein 1253 11503 21753
Re01 .g 12660 VHS domain protein 1254 11504 21754
RLI and DUF367 domain protein
Re01 .g12670 (AFU.orthologue AFUAJ G06690) 1255 11505 21755
Re01 .g12680 Uncharacterized protein Fragment 1256 11506 21756
Re01 .g12690 C6 transcription factor, putative 1257 11507 21757
Re01 .g12700 Uncharacterized protein 1258 11508 21758
T-complex protein 1 , eta subunit,
Re01 .g12710 putative 1259 11509 21759
Histone acetyltransferase Spt10,
Re01 .g12720 putative 1260 11510 21760
Lanthionine synthetase C family
Re01 .g12730 protein, putative 1261 11511 21761
Leucine Rich Repeat domain
Re01 .g 12740 protein 1262 11512 21762
Re01 .g12750 40S ribosomal protein S26 1263 11513 21763
Re01 .g12760 CBS and PB1 domain protein 1264 11514 21764
Re01 .g12770 Importin beta-3 subunit, putative 1265 11515 21765
Re01 .g12780 Putative uncharacterized protein 1266 11516 21766
Re01 .g12790 Predicted protein 1267 11517 21767
NACHT and Ankyrin domain
Re01.g12800 protein 1268 11518 21768 Fe-containing alcohol
Re01.g12810 dehydrogenase, putative, partial 1269 1 1519 21769
Re01.g12820 Aconitate hydratase, mitochondrial 1270 1 1520 21770
Re01.g12830 Putative uncharacterized protein 1271 1 1521 21771
Re01.g12840 60S acidic ribosomal protein P1 1272 1 1522 21772 30915 32405
Vacuolar membrane PQ loop
Re01.g12850 repeat protein 1273 1 1523 21773
Re01.g12860 Uncharacterized protein 1274 1 1524 21774
Re01.g12870 Uncharacterized protein 1275 1 1525 21775
Protein phophatase 2C family
Re01.g12880 protein 1276 1 1526 21776
Re01.g12890 Putative uncharacterized protein 1277 1 1527 21777
Alpha- 1 ,2-mannosyltransferase
Re01.g12900 (Alg1 1), putative 1278 1 1528 21778 30916 32406
C2H2 transcription factor Crz1 ,
Re01.g12910 putative 1279 1 1529 21779
Serine/threonine protein kinase,
Re01.g12920 putative 1280 1 1530 21780
Re01.g12930 hypothetical protein 1281 1 1531 21781
Re01.g12940 Uncharacterized protein 1282 1 1532 21782
Re01.g12950 Putative uncharacterized protein 1283 1 1533 21783 30917 32407
Lipoyltransferase and lipoate-
Re01.g12960 protein ligase, putative 1284 1 1534 21784
Re01.g12970 Chorismate synthase EC=4.2.3.5 1285 1 1535 21785
Re01.g12980 Putative uncharacterized protein 1286 1 1536 21786
Re01.g12990 Glycosyltransferase family protein 1287 1 1537 21787
Re01.g13000 Short chain dehydrogenase 1288 1 1538 21788
Methionyl-tRNA formyltransferase
Re01.g13010 family protein, putative 1289 1 1539 21789
Re01.g13020 Putative uncharacterized protein 1290 1 1540 21790
Re01.g13030 Rho GTPase Rho1 1291 1 1541 21791
Re01.g13040 KOW motif domain protein 1292 1 1542 21792
Re01.g13050 Histone chaperone rtt106 1293 1 1543 21793
Re01.g13060 Casein kinase, putative 1294 1 1544 21794
Re01.g13070 Putative uncharacterized protein 1295 1 1545 21795
Re01.g13080 Pc16g05520 protein 1296 1 1546 21796
Re01.g13090 Pc12g16160 protein 1297 1 1547 21797
Re01.g13100 hypothetical protein 1298 1 1548 21798
Regulator of G protein signaling
Re01.g131 10 domain protein RgsD 1299 1 1549 21799
Re01.g13120 DUF647 domain protein 1300 1 1550 21800
Re01.g13130 Putative uncharacterized protein 1301 1 1551 21801
Mediator of RNA polymerase II
Re01.g13140 transcription subunit 18 1302 1 1552 21802
DNA 3'-phosphatase Tpp1 ,
Re01.g13150 putative 1303 1 1553 21803
Re01.g13160 Uncharacterized protein 1304 1 1554 21804
Endosomal cargo receptor (Erp5),
Re01.g13170 putative 1305 1 1555 21805 30918 32408 DNA methyltransferase 1 -
Re01 ■9' 3180 associated protein DMAP1 1306 1 1556 21806
Re01 ■g' 3190 Putative uncharacterized protein 1307 1 1557 21807
Cobalamin-independent
Re01 ■g' 3200 methionine synthase MetH/D 1308 1 1558 21808
3-oxo-5-alpha-steroid 4-
Re01 ■g' 3210 dehydrogenase family protein 1309 1 1559 21809 30919 32409
Re01 ■g' 3220 Ubiquitin conjugation factor E4 1310 1 1560 21810
ER associated DnaJ chaperone
Re01 ■g' 3230 (Hlj1 ), putative 131 1 1 1561 2181 1
Similarity to hypothetical protein
Re01 ■g' 3240 B23I1 1.140 1312 1 1562 21812
Re01 ■g' 3250 Uncharacterized protein 1313 1 1563 21813
Re01 ■g' 3260 hypothetical protein 1314 1 1564 21814 30920 32410
Re01 ■g' 3270 Uncharacterized protein 1315 1 1565 21815 30921 3241 1
Re01 ■g' 3280 Uncharacterized protein 1316 1 1566 21816
Re01 ■g' 3290 hypothetical protein 1317 1 1567 21817 30922 32412
Cell morphogenesis protein Sog2,
Re01 ■g' 3300 putative 1318 1 1568 21818
Re01 ■g' 3310 Putative uncharacterized protein 1319 1 1569 21819
Re01 ■g' 3320 37S ribosomal protein Rsm25 1320 1 1570 21820
Re01 ■g' 3330 Pentatricopeptide repeat protein 1321 1 1571 21821
RecQ family helicase RecQ,
Re01 ■g' 3340 putative 1322 1 1572 21822
Re01 ■g' 3350 KH domain-containing protein 1323 1 1573 21823
Mitochondrial acetolactate
Re01 ■g' 3360 synthase small subunit, putative 1324 1 1574 21824 30923 32413
Re01 ■g' 3370 Uncharacterized protein 1325 1 1575 21825
Re01 ■g' 3380 Ornithine carbamoyltransferase 1326 1 1576 21826
Re01 ■g' 3390 Pc22g 18380 protein 1327 1 1577 21827
Re01 ■g' 3400 Quinone oxidoreductase, putative 1328 1 1578 21828
Re01 ■g' 3410 Putative uncharacterized protein 1329 1 1579 21829
Methyltransferase LaeA-like,
Re01 ■g' 3420 putative 1330 1 1580 21830
Tethering factor for nuclear
Re01 ■g' 3430 proteasome stsl 1331 1 1581 21831
ATP dependent RNA helicase
Re01 ■g' 3440 (Dob1 ), putative 1332 1 1582 21832
Putative uncharacterized protein
Re01 ■g' 3450 An04g01560 EC=1.9.3.1 1333 1 1583 21833 30924 32414
Re01 ■g' 3460 IKI3 family protein 1334 1 1584 21834
Diphosphomevalonate
Re01 ■g' 3470 decarboxylase EC=4.1.1.33 1335 1 1585 21835
Re01 ■g' 3480 Cytochrome d heme lyase 1336 1 1586 21836
Re01 ■g' 3490 Putative uncharacterized protein 1337 1 1587 21837
Re01 ■g' 3500 Nuclear envelope protein, putative 1338 1 1588 21838 30925 32415
Gag/polymerase/env polyprotein,
Re01 ■g' 3510 putative 1339 1 1589 21839
Re01 ■g' 3520 C2H2 finger domain protein 1340 1 1590 21840 Re01■9' 3530 hypothetical protein 1341 1 1591 21841
Re01 ■g' 3540 Uncharacterized protein 1342 1 1592 21842
Re01 ■g' 3550 Putative uncharacterized protein 1343 1 1593 21843
Re01 ■g' 3560 Acyl-CoA thioesterase 1344 1 1594 21844
Re01 ■g' 3570 L-lactate dehydrogenase 1345 1 1595 21845
Aspartic-type endopeptidase
Re01 ■g' 3580 (CtsD), putative 1346 1 1596 21846 30926 32416
Re01 ■g' 3590 hypothetical protein 1347 1 1597 21847 30927 32417
Re01 ■g' 3600 Putative uncharacterized protein 1348 1 1598 21848
Mitochondrial cytochrome b2,
Re01 ■g' 3610 putative 1349 1 1599 21849
Hydrolase, TatD family protein,
Re01 ■g' 3620 putative 1350 1 1600 21850
Re01 ■g' 3630 Putative uncharacterized protein 1351 1 1601 21851
Re01 ■g' 3640 Amino acid transporter 1352 1 1602 21852
Re01 ■g' 3650 Uncharacterized protein 1353 1 1603 21853
Re01 ■g' 3660 RAD52 DNA repair protein RADC 1354 1 1604 21854
Re01 ■g' 3670 UBX domain protein, putative 1355 1 1605 21855
Integral ER membrane protein
Re01 ■g' 3680 Scs2, putative 1356 1 1606 21856
Re01 ■g' 3690 Sphingolipid desaturase, putative 1357 1 1607 21857
Methionine aminopeptidase, type
Re01 ■g' 3700 II, putative 1358 1 1608 21858
Re01 ■g' 3710 DnaJ domain protein 1359 1 1609 21859
Outer mitochondrial membrane
Re01 ■g' 3720 protein porin 1360 1 1610 21860
Re01 ■g' 3730 Asparagine synthetase EC=6.3.5.4 1361 1 161 1 21861
Re01 ■g' 3740 Ubiquitin-conjugating enzyme 1362 1 1612 21862
G-patch DNA repair protein
Re01 ■g' 3750 (Drt1 1 1 ), putative 1363 1 1613 21863
Peroxisomal-coenzyme A
Re01 ■g' 3760 synthetase 1364 1 1614 21864
Glycosyltransferase family 69
Re01 ■g' 3770 protein 1365 1 1615 21865 30928 32418
Re01 ■g' 3780 Uncharacterized protein 1366 1 1616 21866
Re01 ■g' 3790 Uncharacterized protein 1367 1 1617 21867 30929 32419
Mannan polymerase II complex
Re01 ■g' 3800 ANP1 subunit 1368 1 1618 21868 30930 32420
Re01 ■g' 3810 Uncharacterized protein 1369 1 1619 21869
DNA-3-methyladenine glycosylase,
Re01 ■g' 3830 putative 1370 1 1620 21870
Cytochrome b-d complex subunit
Re01 ■g' 3840 7 1371 1 1621 21871
Re01 ■g' 3850 Putative uncharacterized protein 1372 1 1622 21872
Re01 ■g' 3860 Uncharacterized protein 1373 1 1623 21873 30931 32421
Mitochondrial carrier protein,
Re01 ■g' 3870 putative 1374 1 1624 21874
Re01 ■g' 3880 hypothetical protein 1375 1 1625 21875 30932 32422
Re01 ■g' 3890 hypothetical protein 1376 1 1626 21876 30933 32423 Ubiquinone biosynthesis protein,
Re01 ■g 3900 putative 1377 1 1627 21877 30934 32424
Re01 ■g 3910 Serine-threonine kinase SepH 1378 1 1628 21878
Re01 ■g 3920 Dihydrofolate synthetase Fol3 1379 1 1629 21879
Re01 ■g 3930 Uncharacterized protein 1380 1 1630 21880
Re01 ■g 3940 Uncharacterized protein 1381 1 1631 21881
Re01 ■g 3950 Kinase-related protein 1382 1 1632 21882
Re01 ■g 3960 Predicted protein 1383 1 1633 21883 30935 32425
Re01 ■g 3970 hypothetical protein 1384 1 1634 21884 30936 32426
Ribonucleotide reductase large
Re01 ■g 3980 subunit RNR1 , putative 1385 1 1635 21885
Re01 ■g 3990 Putative uncharacterized protein 1386 1 1636 21886 30937 32427
Terpene synthase metal binding
Re01 ■g 4000 domain protein 1387 1 1637 21887
Re01 ■g 4010 Allergen Asp F7 1388 1 1638 21888 30938 32428
Re01 ■g 4020 MFS transporter, putative 1389 1 1639 21889
Re01 ■g 4030 hypothetical protein 1390 1 1640 21890
Re01 ■g 4040 Predicted protein 1391 1 1641 21891
Glutamate/Leucine/Phenylalanine/
Re01 ■g 4050 Valine dehydrogenase, putative 1392 1 1642 21892
Re01 ■g 4060 Aldo-keto reductase, putative 1393 1 1643 21893
Re01 ■g 4070 hypothetical protein 1394 1 1644 21894
Re01 ■g 4080 Uncharacterized protein 1395 1 1645 21895
Mediator of RNA polymerase II
Re01 ■g 4090 transcription subunit 5 1396 1 1646 21896
Ras guanine-nucleotide exchange
Re01 ■g 4100 protein, putative 1397 1 1647 21897
Re01 ■g 41 10 Predicted protein 1398 1 1648 21898
Re01 ■g 4120 Putative uncharacterized protein 1399 1 1649 21899
BZIP transcription factor (MetR),
Re01 ■g 4130 putative 1400 1 1650 21900
Re01 ■g 4140 Uncharacterized protein 1401 1 1651 21901
Re01 ■g 4160 DUF974 domain protein 1402 1 1652 21902
Re01 ■g 4170 hypothetical protein 1403 1 1653 21903 30939 32429
Re01 ■g 4180 DDENN domain protein 1404 1 1654 21904
Pentafunctional AROM
Re01 ■g 4190 polypeptide, putative 1405 1 1655 21905
Re01 ■g 4200 Pc22g 17270 protein 1406 1 1656 21906
pH signal transduction protein
Re01 ■g 4210 PalA, putative 1407 1 1657 21907
Mitochondrial carrier protein,
Re01 ■g 4220 putative 1408 1 1658 21908
Re01 ■g 4230 Sterol carrier protein, putative 1409 1 1659 21909
Re01 ■g 4240 hypothetical protein 1410 1 1660 21910 30940 32430
Re01 ■g 4250 Putative uncharacterized protein 141 1 1 1661 2191 1 30941 32431
Re01 ■g 4260 Predicted protein 1412 1 1662 21912
Re01 ■g 4270 rRNA processing protein gar2 1413 1 1663 21913
Re01 ■g 4280 Uncharacterized protein 1414 1 1664 21914
Re01 ■g 4290 Protein getl 1415 1 1665 21915 30942 32432 Re01.g14300 Putative uncharacterized protein 1416 11666 21916
Re01.g14310 Kinesin 1417 11667 21917
Similarity to hypothetical protein
Re01.g14320 CAC28557.1 1418 11668 21918
Re01.g14330 Putative uncharacterized protein 1419 11669 21919
Re01.g14340 Uncharacterized protein Fragment 1420 11670 21920 30943 32433
Re01.g14350 Uncharacterized protein 1421 11671 21921 30944 32434
Re01.g14360 Putative uncharacterized protein 1422 11672 21922
Mating-type switch/DNA repair
Re01.g14370 protein Swi10/Rad10, putative 1423 11673 21923
Ribosome biogenesis (Nop4),
Re01.g14380 putative 1424 11674 21924
Progesterone binding protein,
Re01.g14390 putative 1425 11675 21925
Re01.g14400 hypothetical protein 1426 11676 21926
Re01.g14410 JmjC domain protein 1427 11677 21927
Re01.g14420 Uncharacterized protein 1428 11678 21928
Fungal specific transcription factor,
Re01.g14430 putative 1429 11679 21929
ReOl .g 14440 Casein kinase II beta subunit CKB1 1430 11680 21930
Re01.g14450 Ankyrin repeat protein 1431 11681 21931
Re01.g14460 hypothetical protein 1432 11682 21932
Re01.g14470 Uncharacterized protein 1433 11683 21933
Re01.g14480 hypothetical protein 1434 11684 21934
Gag/polymerase/env polyprotein,
Re01.g14490 putative 1435 11685 21935
Branched-chain amino acid
Re01.g14500 aminotransferase, cytosolic 1436 11686 21936
Re01.g14510 Protein kinase Scy1 , putative 1437 11687 21937
Re01.g14520 Dipeptidyl peptidase, putative 1438 11688 21938
Re01.g14530 SNF5/SMARCB1/INI1 protein 1439 11689 21939
Re01.g14540 Predicted protein 1440 11690 21940
Re01.g14550 Putative uncharacterized protein 1441 11691 21941
Re01.g14560 Protein transport protein sec13 1442 11692 21942
Re01.g14570 MFS myo-inositol transporter 1443 11693 21943
Translation initiation regulator
Re01.g14580 (Gcn20), putative 1444 11694 21944
Re01.g14590 Putative uncharacterized protein 1445 11695 21945 30945 32435
Re01.g14600 MFS multidrug transporter, putative 1446 11696 21946
Re01.g14610 Putative uncharacterized protein 1447 11697 21947
Re01.g14620 Uncharacterized protein 1448 11698 21948 30946 32436
Re01.g14630 Ankyrin repeat protein nuc-2 1449 11699 21949
Peptide alpha-N-acetyltransferase
Re01.g14640 Nat2, putative 1450 11700 21950
Re01.g14650 50S ribosomal protein L3 1451 11701 21951
Cytochrome oxidase complex
Re01.g14660 assembly protein 1452 11702 21952
Re01.g14670 Uncharacterized protein 1453 11703 21953
Re01.g14680 JmjC domain protein, putative 1454 11704 21954 4-hydroxybenzoate polyprenyl
transferase family protein
Re01 ■g 4690 EC=2.5.1.- 1455 1 1705 21955
Re01 ■g 4700 Putative uncharacterized protein 1456 1 1706 21956
Re01 ■g 4710 Monothiol glutaredoxin-5 1457 1 1707 21957 30947 32437
Re01 ■g 4720 Putative uncharacterized protein 1458 1 1708 21958
Re01 ■g 4730 Putative uncharacterized protein 1459 1 1709 21959
Re01 ■g 4740 Protein MSF1 1460 1 1710 21960
Disrupter of telomere silencing
Re01 ■g 4750 protein Dot5, putative 1461 1 171 1 21961
NADH-ubiquinone oxidoreductase
Re01 ■g 4760 21 kDa subunit, putative 1462 1 1712 21962
Re01 ■g 4770 Putative uncharacterized protein 1463 1 1713 21963 30948 32438
Re01 ■g 4780 Putative uncharacterized protein 1464 1 1714 21964
U3 small nucleolar
Re01 ■g 4790 ribonucleoprotein protein Mpp10 1465 1 1715 21965
Oxidoreductase, short-chain
Re01 ■g 4800 dehydrogenase/reductase family 1466 1 1716 21966
NADH-ubiquinone oxidoreductase
Re01 ■g 4810 subunit B, putative 1467 1 1717 21967
Re01 ■g 4820 Putative uncharacterized protein 1468 1 1718 21968
Malonyl CoA-acyl carrier protein
Re01 ■g 4830 transacylase, putative 1469 1 1719 21969
Re01 ■g 4840 Uncharacterized protein Fragment 1470 1 1720 21970
Gag/polymerase/env polyprotein,
Re01 ■g 4850 putative 1471 1 1721 21971
Re01 ■g 4860 Retrovirus polyprotein, putative 1472 1 1722 21972
Re01 ■g 4870 Putative uncharacterized protein 1473 1 1723 21973
Re01 ■g 4880 Putative uncharacterized protein 1474 1 1724 21974
Re01 ■g 4890 Uncharacterized protein 1475 1 1725 21975
Re01 ■g 4900 hypothetical protein 1476 1 1726 21976
Re01 ■g 4910 Uncharacterized protein Fragment 1477 1 1727 21977
Re01 ■g 4920 Predicted protein 1478 1 1728 21978
Re01 ■g 4930 Putative uncharacterized protein 1479 1 1729 21979
Re01 ■g 4940 Putative uncharacterized protein 1480 1 1730 21980
Putative uncharacterized protein
Re01 ■g 4950 Fragment 1481 1 1731 21981
Fe-S cluster assembly protein
Re01 ■g 4960 DRE2 1482 1 1732 21982
Delta-aminolevulinic acid
Re01 ■g 4970 dehydratase EC=4.2.1.24 1483 1 1733 21983
Re01 ■g 4980 C6 zinc finger domain protein 1484 1 1734 21984
Re01 ■g 4990 Exportin KapK 1485 1 1735 21985
Re01 ■g 5000 Uncharacterized protein 1486 1 1736 21986
Re01 ■g 5010 Putative uncharacterized protein 1487 1 1737 21987
Re01 ■g 5020 hypothetical protein 1488 1 1738 21988 30949 32439
Re01 ■g 5030 hypothetical protein 1489 1 1739 21989 30950 32440
Type 1 phosphatases regulator
Re01.g15040 ypil 1490 1 1740 21990 Re01■9' 5050 Shugoshin family protein 1491 11741 21991
Re01 ■g' 5060 Putative uncharacterized protein 1492 11742 21992
Re01 ■g' 5070 Uncharacterized protein 1493 11743 21993
Re01 ■g' 5080 Putative uncharacterized protein 1494 11744 21994
Glycerol-3-phosphate
Re01 ■g' 5090 dehydrogenase, mitochondrial 1495 11745 21995 30951 32441
Re01 ■g' 5100 Putative uncharacterized protein 1496 11746 21996
Re01 ■g' 5110 Putative coiled-coil protein 1497 11747 21997
Re01 ■g' 5120 Guanylate kinase 1498 11748 21998
Re01 ■g' 5130 Guanylate kinase 1499 11749 21999
Re01 ■g' 5140 Septin 1500 11750 22000
Meiotic recombination protein
Re01 ■g' 5150 Ski8/Rec14, putative 1501 11751 22001 30952 32442
Re01 ■g' 5160 Uncharacterized protein 1502 11752 22002
Re01 ■g' 5170 Uncharacterized protein 1503 11753 22003
Iron/copper transporter Atx1 ,
Re01 ■g' 5180 putative 1504 11754 22004
Re01 ■g' 5190 Putative uncharacterized protein 1505 11755 22005
CHY and RING finger domain
Re01 ■g' 5200 protein, putative 1506 11756 22006
MFS transporter, SP family,
Re01 ■g' 5210 sugar:H+ symporter 1507 11757 22007
Re01 ■g' 5220 Putative uncharacterized protein 1508 11758 22008
Re01 ■g' 5230 Uncharacterized protein 1509 11759 22009
Cytosolic iron-sulfur protein
Re01 ■g' 5240 assembly protein 1 1510 11760 22010
Pheromone-processing
carboxypeptidase kexl
Re01 ■g' 5250 EC=3.4.16.6 Precursor 1511 11761 22011 30953 32443
Re01 ■g' 5260 DUF431 domain protein 1512 11762 22012
CAMP- regulated phosphoprotein
Re01 ■g' 5270 family protein lgo1 , putative 1513 11763 22013
Re01 ■g' 5280 Uncharacterized protein 1514 11764 22014 30954 32444
Re01 ■g' 5290 Uncharacterized protein 1515 11765 22015
Nuclear pore complex protein
Re01 ■g' 5300 (Son A), putative 1516 11766 22016
Re01 ■g' 5310 Putative uncharacterized protein 1517 11767 22017
Re01 ■g' 5320 Pc16g12710 protein Precursor 1518 11768 22018 30955 32445
Intermediate filament protein
Re01 ■g' 5330 (Mdm1), putative 1519 11769 22019
Re01 ■g' 5340 Phospholipid methyltransferase 1520 11770 22020
Re01 ■g' 5350 Putative uncharacterized protein 1521 11771 22021
Re01 ■g' 5360 Putative uncharacterized protein 1522 11772 22022
Hydrolase, alpha/beta fold family
Re01 ■g' 5370 protein 1523 11773 22023
Re01 ■g' 5380 Glutaredoxin domain protein 1524 11774 22024 30956 32446
60S ribosomal protein L9, putative
Re01 ■g' 5390 (AFU.orthologue AFUAJ G09100) 1525 11775 22025
Re01 ■g' 5400 Patatin-like serine hydrolase, 1526 11776 22026 30957 32447 putative
Re01.g15410 Predicted protein 1527 11777 22027
Re01.g15420 Transcription factor btf3, putative 1528 11778 22028
Re01.g15430 Putative uncharacterized protein 1529 11779 22029
ReOl .g 15440 Amino acid permease, putative 1530 11780 22030
ReOl .g 15450 Rhomboid family protein 1531 11781 22031 30958 32448
ReOl .g 15460 Uncharacterized protein 1532 11782 22032
Cell cycle-associated protein
Re01.g15470 Mob1-1 1533 11783 22033
Re01.g15480 Uncharacterized protein 1534 11784 22034
Re01.g15490 C6 finger domain protein 1535 11785 22035
Re01.g15500 Pc12g 15770 protein 1536 11786 22036 30959 32449
Re01.g15510 Uncharacterized protein 1537 11787 22037
Integral plasma membrane protein,
Re01.g15520 putative 1538 11788 22038
Cleavage and polyadenylylation
Re01.g15530 specificity factor, putative 1539 11789 22039
ReOl .g 15540 Uncharacterized protein 1540 11790 22040
Re01.g15550 Uncharacterized protein 1541 11791 22041 30960 32450
Re01.g15560 Uncharacterized protein 1542 11792 22042
Re01.g15570 hypothetical protein 1543 11793 22043
Re01.g15580 hypothetical protein 1544 11794 22044 30961 32451
Extracellular thaumatin domain
Re01.g15590 protein, putative 1545 11795 22045 30962 32452
Re01.g15600 hypothetical protein 1546 11796 22046 30963 32453
Re01.g15610 Sec23/Sec24 family protein 1547 11797 22047
Re01.g15620 Amino-acid permease, putative 1548 11798 22048
Re01.g15630 ABC efflux transporter, putative 1549 11799 22049
ReOl .g 15640 C6 transcription factor OefC 1550 11800 22050
Re01.g15650 Uncharacterized protein 1551 11801 22051
Re01.g15670 Uncharacterized protein Fragment 1552 11802 22052
Re01.g15680 Reverse transcriptase, putative 1553 11803 22053
DSB repair complex subunit Ku70,
Re01.g15690 putative 1554 11804 22054
Re01.g15700 Ferrochelatase EC=4.99.1.1 1555 11805 22055
Tetracycline-efflux transporter,
Re01.g15710 putative 1556 11806 22056
Re01.g15720 Pentatricopeptide repeat protein 1557 11807 22057
Re01.g15730 Squalene epoxidase 1558 11808 22058
Re01.g15740 PAP/25A associated domain family 1559 11809 22059
Re01.g15750 Uncharacterized protein 1560 11810 22060
Re01.g15760 Putative membrane protein 1561 11811 22061
Re01.g15770 DUF625 domain protein, putative 1562 11812 22062
Re01.g15780 Uncharacterized protein 1563 11813 22063 30964 32454
Inositol polyphosphate 5-
Re01.g15790 phosphatase 1564 11814 22064
Re01.g15800 Decapping enzyme Dcp1 1565 11815 22065
Re01.g15810 Uncharacterized protein 1566 11816 22066
Re01.g15820 hypothetical protein 1567 11817 22067 Re01■g 5830 Uncharacterized protein 1568 1 1818 22068
Re01 ■g 5840 Uncharacterized protein 1569 1 1819 22069 30965 32455
Single-stranded DNA-binding
Re01 ■g 5850 protein 1570 1 1820 22070 30966 32456
Re01 ■g 5860 Putative uncharacterized protein 1571 1 1821 22071
Re01 ■g 5870 Putative uncharacterized protein 1572 1 1822 22072
Re01 ■g 5880 AP-2 complex subunit mu 1573 1 1823 22073
Re01 ■g 5890 80 kD MCM3-associated protein 1574 1 1824 22074
Re01 ■g 5900 Uncharacterized protein 1575 1 1825 22075
Re01 ■g 5910 Putative uncharacterized protein 1576 1 1826 22076
Re01 ■g 5920 ABC metal ion transporter 1577 1 1827 22077
Re01 ■g 5930 PfkB family kinase, putative 1578 1 1828 22078
Re01 ■g 5940 Uncharacterized protein 1579 1 1829 22079
Re01 ■g 5950 Uncharacterized protein 1580 1 1830 22080
Re01 ■g 5960 Putative uncharacterized protein 1581 1 1831 22081 30967 32457
C2H2 finger and ankyrin domain
Re01 ■g 5970 protein, putative 1582 1 1832 22082
Putative uncharacterized protein
Re01 ■g 5980 An12g09560 EC=1.14.-.- 1583 1 1833 22083
Re01 ■g 5990 Putative uncharacterized protein 1584 1 1834 22084 30968 32458
Re01 ■g 6000 HLH DNA binding protein 1585 1 1835 22085
Re01 ■g 6010 Pc22g 15850 protein 1586 1 1836 22086
Re01 ■g 6020 hypothetical protein 1587 1 1837 22087
Re01 ■g 6030 Emopamil binding protein 1588 1 1838 22088
tRNA splicing 2'
Re01 ■g 6040 phosphotransferase 1 1589 1 1839 22089
Re01 ■g 6050 hypothetical protein 1590 1 1840 22090
Re01 ■g 6060 Uncharacterized protein 1591 1 1841 22091
Serine/threonine protein kinase,
Re01 ■g 6070 putative 1592 1 1842 22092
Re01 ■g 6080 Putative uncharacterized protein 1593 1 1843 22093
Re01 ■g 6090 Putative uncharacterized protein 1594 1 1844 22094
Re01 ■g 6100 Putative uncharacterized protein 1595 1 1845 22095 30969 32459
Re01 ■g 61 10 Putative cutinase 1596 1 1846 22096 30970 32460
Re01 ■g 6120 Putative uncharacterized protein 1597 1 1847 22097
Oligomycin resistance ATP- dependent permease yorl , putative
Re01 ■g 6130 EC=1.3.1.74 1598 1 1848 22098
Re01 ■g 6140 Putative uncharacterized protein 1599 1 1849 22099 30971 32461
Exocyst complex component Sec8,
Re01 ■g 6150 putative 1600 1 1850 22100
Probable Xaa-Pro aminopeptidase
Re01 ■g 6160 P EC=3.4.1 1.9 1601 1 1851 22101
Re01 ■g 6170 Importin 13 1602 1 1852 22102
Re01 ■g 6180 Pyridoxine biosynthesis protein 1603 1 1853 22103
Re01 ■g 6190 Putative uncharacterized protein 1604 1 1854 22104 30972 32462
Origin recognition complex subunit
Re01 ■g 6200 2, putative 1605 1 1855 22105
Re01 ■g 6210 Arginine biosynthesis bifunctional 1606 1 1856 22106 protein ArgJ, mitochondrial
EC=2.3.1.35 EC=2.3.1.1 Precursor
Protein transport protein Sec61
Re01.g16220 alpha subunit, putative 1607 11857 22107
Re01.g16230 Uncharacterized protein 1608 11858 22108
Re01.g16240 Putative uncharacterized protein 1609 11859 22109
Re01.g16250 Uncharacterized protein 1610 11860 22110
Re01.g16260 Cyclin, putative 1611 11861 22111
Re01.g16270 Autophagy-related protein 3 1612 11862 22112
Re01.g16280 hypothetical protein 1613 11863 22113
Re01.g16290 hypothetical protein 1614 11864 22114 30973 32463
Re01.g16300 Putative uncharacterized protein 1615 11865 22115
Re01.g16310 Uncharacterized protein 1616 11866 22116
Dolichyl-phosphate beta-
Re01.g16320 glucosyltransferase, putative 1617 11867 22117
Re01.g16330 Putative uncharacterized protein 1618 11868 22118
Re01.g16340 Uncharacterized protein 1619 11869 22119
Re01.g16350 C3HC4 finger protein 1620 11870 22120
Nucleoside diphosphate-sugar
Re01.g16360 hydrolase of the MutT 1621 11871 22121
Re01.g16370 MutT/nudix family protein 1622 11872 22122
HAD superfamily hydrolase,
Re01.g16380 putative 1623 11873 22123
tRNA a64-2'-o-ribosylphosphate
Re01.g16390 transferase 1624 11874 22124
Re01.g16400 Aldo-keto reductase 1625 11875 22125
Re01.g16410 Uncharacterized protein 1626 11876 22126
Re01.g16420 RNA binding protein, putative 1627 11877 22127
Re01.g16430 WD repeat protein 1628 11878 22128
Polyubiquitin binding protein
ReOl .g 16440 (Doa1/Ufd3), putative 1629 11879 22129
Re01.g16450 AI-BP family protein 1630 11880 22130
Re01.g16460 37S ribosomal protein S16 1631 11881 22131
Re01.g16470 hypothetical protein 1632 11882 22132 30974 32464
Re01.g16480 RNA binding protein 1633 11883 22133
Re01.g16490 Uncharacterized protein 1634 11884 22134
Re01.g16500 60S ribosomal protein L30, putative 1635 11885 22135
HLH DNA binding domain protein,
Re01.g16510 putative 1636 11886 22136
Re01.g16520 Response regulator, putative 1637 11887 22137
Re01.g16530 PQ loop repeat protein 1638 11888 22138
Re01.g16540 Putative uncharacterized protein 1639 11889 22139
High osmolarity signaling protein
Re01.g16550 shol 1640 11890 22140
Nuclear distribution protein RO10,
Re01.g16560 putative 1641 11891 22141
Re01.g16570 Putative uncharacterized protein 1642 11892 22142
Re01.g16580 AMP-binding enzyme, putative 1643 11893 22143
Re01.g16590 Serine/threonine protein kinase 1644 11894 22144 PRR2
Re01 ■g 6600 Putative uncharacterized protein 1645 1 1895 22145
Re01 ■g 6610 Putative uncharacterized protein 1646 1 1896 22146 30975 32465
Re01 ■g 6620 Dynein light intermediate chain 1647 1 1897 22147
Re01 ■g 6630 RNA binding domain protein 1648 1 1898 22148
Remark: the ORF contains WD-
Re01 ■g 6640 re peats 1649 1 1899 22149 30976 32466
Re01 ■g 6650 Septin AspA, putative 1650 1 1900 22150 30977 32467
Rho1 guanine nucleotide exchange
Re01 ■g 6660 factor 1 1651 1 1901 22151
Putative uncharacterized protein
Re01 ■g 6670 An07g05080 EC=3.6.3.6 Precursor 1652 1 1902 22152
cAMP-dependent protein kinase
Re01 ■g 6680 catalytic subunit, putative 1653 1 1903 22153
Alpha- 1 ,6-mannosyltransferase
Re01 ■g 6690 subunit (Och1), putative 1654 1 1904 22154 30978 32468
Re01 ■g 6710 Homoserine O-acetyltransferase 1655 1 1905 22155
Re01 ■g 6720 ThiF domain protein 1656 1 1906 22156 30979 32469
Re01 ■g 6730 Ser/Thr protein phosphatase family 1657 1 1907 22157
Re01 ■g 6740 LCCL domain protein 1658 1 1908 22158
Re01 ■g 6750 Uncharacterized protein 1659 1 1909 22159
Re01 ■g 6760 Monooxygenase, putative 1660 1 1910 22160 30980 32470
Re01 ■g 6770 hypothetical protein 1661 1 191 1 22161
Re01 ■g 6780 Putative uncharacterized protein 1662 1 1912 22162 30981 32471
Re01 ■g 6790 Integral membrane protein 1663 1 1913 22163
Re01 ■g 6800 Uncharacterized protein 1664 1 1914 22164
Similarity to hypothetical protein
Re01 ■g 6810 BAA90881.1 1665 1 1915 22165
Phosphatidylinositol 3-kinase
Re01 ■g 6820 EC=2.7.1.137 1666 1 1916 22166
Cyclohexanone 1 ,2-
Re01 ■g 6830 monooxygenase 1667 1 1917 22167
Re01 ■g 6840 Putative uncharacterized protein 1668 1 1918 22168
Re01 ■g 6850 Similar to alcohol dehydrogenase 1669 1 1919 22169 30982 32472
Re01 ■g 6860 Pc16g00330 protein 1670 1 1920 22170
Re01 ■g 6870 Polyketide synthase, putative 1671 1 1921 22171
Re01 ■g 6880 Polyketide synthase 1672 1 1922 22172
Re01 ■g 6890 Uncharacterized protein 1673 1 1923 22173
Re01 ■g 6900 C6 finger domain protein GliZ 1674 1 1924 22174
Re01 ■g 6910 Uncharacterized protein 1675 1 1925 22175
Re01 ■g 6920 Salicylate hydroxylase, putative 1676 1 1926 22176 30983 32473
Re01 ■g 6930 Alternative oxidase EC=1 1677 1 1927 22177 30984 32474
Re01 ■g 6940 hypothetical protein 1678 1 1928 22178
MFS monocarboxylate transporter,
Re01 ■g 6950 putative 1679 1 1929 22179
Tartrate-resistant acid phosphatase
Re01 ■g 6960 type 5, putative 1680 1 1930 22180 30985 32475
Re01 ■g 6970 Uncharacterized protein 1681 1 1931 22181
Re01 ■g 6980 Putative uncharacterized protein 1682 1 1932 22182 Re01■9' 6990 Uncharacterized protein 1683 1 1933 22183
Arsenic resistance protein ArsH,
Re01 ■g' 7000 putative EC=1.5.1.- 1684 1 1934 22184
Arsenite efflux transporter (ArsB),
Re01 ■g' 7010 putative 1685 1 1935 22185
Gag/polymerase/env polyprotein,
Re01 ■g' 7020 putative 1686 1 1936 22186
Re01 ■g' 7040 Putative uncharacterized protein 1687 1 1937 22187
Putative myo-inositol 2-
Re01 ■g' 7050 dehydrogenase protein 1688 1 1938 22188
Re01 ■g' 7060 Vegetative cell wall protein gp1 1689 1 1939 22189
Glycoside hydrolase family 3
Re01 ■g' 7070 protein 1690 1 1940 22190
Re01 ■g' 7080 Predicted protein 1691 1 1941 22191 30986 32476
Putative umta methyltransferase
Re01 ■g' 7090 family protein 1692 1 1942 22192
Re01 ■g' 7100 Putative uncharacterized protein 1693 1 1943 22193
Re01 ■g' 71 10 Predicted protein 1694 1 1944 22194
Re01 ■g' 7120 Methyltransferase type 12 1695 1 1945 22195
Re01 ■g' 7130 hypothetical protein 1696 1 1946 22196
Re01 ■g' 7140 hypothetical protein 1697 1 1947 22197
WGS project CABTOOOOOOOO data,
Re01 ■g' 7150 contig 2.18 1698 1 1948 22198
Re01 ■g' 7160 hypothetical protein 1699 1 1949 22199
Re01 ■g' 7170 Uncharacterized protein 1700 1 1950 22200
Re01 ■g' 7180 Predicted protein 1701 1 1951 22201
Re01 ■g' 7190 hypothetical protein 1702 1 1952 22202
Re01 ■g' 7200 Putative uncharacterized protein 1703 1 1953 22203 30987 32477
Re01 ■g' 7210 Putative uncharacterized protein 1704 1 1954 22204
Re01 ■g' 7220 Putative uncharacterized protein 1705 1 1955 22205
Re01 ■g' 7230 hypothetical protein 1706 1 1956 22206 30988 32478
Re01 ■g' 7240 Predicted protein 1707 1 1957 22207
Re01 ■g' 7250 Putative uncharacterized protein 1708 1 1958 22208
Re01 ■g' 7260 Putative uncharacterized protein 1709 1 1959 22209
Re01 ■g' 7270 Uncharacterized protein 1710 1 1960 22210
Re01 ■g' 7280 Monooxygenase 171 1 1 1961 2221 1
Re01 ■g' 7290 Putative uncharacterized protein 1712 1 1962 22212
Re01 ■g' 7300 Anion exchange protein, putative 1713 1 1963 22213
Re01 ■g' 7310 Uncharacterized protein 1714 1 1964 22214
Re01 ■g' 7320 Isy1 -like splicing family protein 1715 1 1965 22215
Re01 ■g' 7330 Myosin type II heavy chain 1716 1 1966 22216
Re01 ■g' 7340 Uncharacterized protein 1717 1 1967 22217
Re01 ■g' 7350 Flavin oxidoreductase 1718 1 1968 22218
Phospholipase/carboxylesterase
Re01 ■g' 7360 family protein 1719 1 1969 22219
Re01 ■g' 7370 Putative uncharacterized protein 1720 1 1970 22220
Re01 ■g' 7380 Uncharacterized protein 1721 1 1971 22221
Re01 ■g' 7390 hypothetical protein 1722 1 1972 22222
Re01 ■g' 7400 Palmitoyltransferase EC=2.3.1.- 1723 1 1973 22223 30989 32479 Re01.g17410 hypothetical protein 1724 1 1974 22224
Re01.g17420 Putative uncharacterized protein 1725 1 1975 22225
Re01.g17430 Ribosomal protein L24E 1726 1 1976 22226
ReOl .g 17440 Cell wall glucanase, putative 1727 1 1977 22227
Re01.g17450 Uncharacterized protein 1728 1 1978 22228
Re01.g17460 Putative uncharacterized protein 1729 1 1979 22229 30990 32480
Re01.g17470 Putative uncharacterized protein 1730 1 1980 22230 30991 32481
Woronin body protein HexA,
Re01.g17480 putative 1731 1 1981 22231 30992 32482
Transcriptional regulator (Cti6),
Re01.g17490 putative 1732 1 1982 22232
Re01.g17500 Putative uncharacterized protein 1733 1 1983 22233
Re01.g17510 Putative uncharacterized protein 1734 1 1984 22234
Re01.g17520 Uncharacterized protein 1735 1 1985 22235
Putative nad dependent epimerase
Re01.g17530 protein 1736 1 1986 22236
D-arabinitol dehydrogenase ArbD,
Re01.g17540 putative 1737 1 1987 22237
3-methylcrotonyl-CoA carboxylase
Re01.g17550 subunit alpha (MccA), putative 1738 1 1988 22238
Re01.g17560 Putative uncharacterized protein 1739 1 1989 22239
Catalytic activity: AtlVD activity
requires FAD as a cofactor
Re01.g17570 EC=1.3.99.10 1740 1 1990 22240
3-methylcrotonyl-CoA carboxylase,
Re01.g17580 beta subunit (MccB), putative 1741 1 1991 22241
Re01.g17590 Ras-related protein RSR1 1742 1 1992 22242
Triglyceride lipase-cholesterol
Re01.g17600 esterase, putative 1743 1 1993 22243 30993 32483
Re01.g17610 Pc21 g17330 protein 1744 1 1994 22244
Oligosaccharyl transferase subunit
Re01.g17620 (Beta), putative 1745 1 1995 22245 30994 32484
NADH-ubiquinone oxidoreductase
Re01.g17630 9.5 kDa subunit, putative 1746 1 1996 22246
Re01.g17640 Uncharacterized protein 1747 1 1997 22247
Re01.g17650 Transcription factor RfeG, putative 1748 1 1998 22248
Re01.g17660 hypothetical protein 1749 1 1999 22249 30995 32485
Re01.g17670 DNA polymerase eta (Eurofung) 1750 12000 22250
Re01.g17680 Uncharacterized protein 1751 12001 22251
Re01.g17690 hypothetical protein 1752 12002 22252
ER membrane protein Wsc4,
Re01.g17700 putative 1753 12003 22253 30996 32486
Re01.g17710 NTF2-like protein 1754 12004 22254
Re01.g17720 Uncharacterized protein 1755 12005 22255
Re01.g17730 Uncharacterized protein 1756 12006 22256
Re01.g17740 Putative uncharacterized protein 1757 12007 22257
Re01.g17750 hypothetical protein 1758 12008 22258
Re01.g17760 Putative uncharacterized protein 1759 12009 22259
Re01.g17770 Ankyrin repeat-containing protein, 1760 12010 22260 putative
Re01 ■g' 7780 Uncharacterized protein 1761 1201 1 22261 30997 32487
Re01 ■g' 7790 RNA binding protein, putative 1762 12012 22262
Re01 ■g' 7800 Putative uncharacterized protein 1763 12013 22263 30998 32488
Transcription factor (SPT8),
Re01 ■g' 7810 putative 1764 12014 22264
Re01 ■g' 7820 Uncharacterized protein 1765 12015 22265
Re01 ■g' 7830 hypothetical protein 1766 12016 22266
Re01 ■g' 7840 Putative uncharacterized protein 1767 12017 22267
Re01 ■g' 7850 Cytochrome P450 1768 12018 22268 30999 32489
Permease of the major facilitator
Re01 ■g' 7860 superfamily 1769 12019 22269
Re01 ■g' 7870 ATP-dependent bile acid permease 1770 12020 22270
Re01 ■g' 7880 Putative uncharacterized protein 1771 12021 22271
Re01 ■g' 7890 Uncharacterized protein 1772 12022 22272
Ubiquitin conjugating enzyme
(UbcC), putative (AFU orthologue
Re01 ■g' 7900 AFUA_5G09200) 1773 12023 22273
Putative uncharacterized protein
Re01 ■g' 7910 An07g03750 1774 12024 22274
Transcription factor (Snd1/p100),
Re01 ■g' 7920 putative 1775 12025 22275
Re01 ■g' 7930 hypothetical protein 1776 12026 22276
Re01 ■g' 7940 Uncharacterized protein 1777 12027 22277
Re01 ■g' 7950 Similar to o-methyltransferase 1778 12028 22278
Re01 ■g' 7960 NmrA-like family protein 1779 12029 22279 31000 32490
Re01 ■g' 7970 Endochitinase Fragment 1780 12030 22280
Re01 ■g' 7980 Putative uncharacterized protein 1781 12031 22281
Superoxide dismutase [Cu-Zn]
Re01 ■g' 7990 EC=1.15.1.1 1782 12032 22282
Re01 ■g' 8000 Putative uncharacterized protein 1783 12033 22283
Re01 ■g' 8010 Uncharacterized protein 1784 12034 22284
Re01 ■g' 8020 Transaldolase EC=2.2.1.2 1785 12035 22285
Re01 ■g' 8030 Beige/BEACH domain protein 1786 12036 22286
Re01 ■g' 8040 Autophagic serine protease Alp2 1787 12037 22287 31001 32491
Re01 ■g' 8050 Uncharacterized protein 1788 12038 22288
Putative uncharacterized protein
Re01 ■g' 8060 An02g14730 Precursor 1789 12039 22289 31002 32492
Re01 ■g' 8070 Uncharacterized protein 1790 12040 22290 31003 32493
Re01 ■g' 8080 DUF1479 domain protein 1791 12041 22291
NAD-dependent 15- hydroxyprostaglandin
Re01 ■g' 8090 dehydrogenase 1792 12042 22292
Re01 ■g' 8100 Amino acid transporter, putative 1793 12043 22293
Re01 ■g' 81 10 Bax Inhibitor family protein 1794 12044 22294
Signal transduction protein Syg1 ,
Re01 ■g' 8120 putative 1795 12045 22295
Re01 ■g' 8130 Predicted protein 1796 12046 22296
Re01 ■g' 8140 CipC-like antibiotic response 1797 12047 22297 protein, putative
Phospholipase/Carboxylesterase
Re01 ■g' 8150 superfamily 1798 12048 22298
Re01 ■g' 8160 Uncharacterized protein 1799 12049 22299 31004 32494
Re01 ■g' 8170 Calcineurin catalytic subunit CnaA 1800 12050 22300
Re01 ■g' 8180 Similar to An07g03610 1801 12051 22301
Re01 ■g' 8190 Putative uncharacterized protein 1802 12052 22302
Re01 ■g' 8200 Putative uncharacterized protein 1803 12053 22303 31005 32495
Re01 ■g' 8210 Carbonyl reductase, putative 1804 12054 22304
Re01 ■g' 8220 Putative uncharacterized protein 1805 12055 22305
Clock controled protein (Ccg-8),
Re01 ■g' 8230 putative 1806 12056 22306
RNA-directed RNA polymerase,
Re01 ■g' 8240 putative 1807 12057 22307
Cytochrome P450 alkane
Re01 ■g' 8250 hydroxylase 1808 12058 22308 31006 32496
Ketoacyl-synt-domain-containing
Re01 ■g' 8260 protein 1809 12059 22309
Re01 ■g' 8270 Uncharacterized protein 1810 12060 22310 31007 32497
Similar to EF-hand calcium-binding
Re01 ■g' 8280 domain protein 181 1 12061 2231 1
Re01 ■g' 8290 hypothetical protein 1812 12062 22312
Synaptic vesicle transporter SVOP
Re01 ■g' 8300 and related transporters 1813 12063 22313
Re01 ■g' 8310 Uncharacterized protein 1814 12064 22314
Re01 ■g' 8320 Putative uncharacterized protein 1815 12065 22315
Re01 ■g' 8330 Amino acid transporter 1816 12066 22316
Re01 ■g' 8340 Isoflavone reductase family protein 1817 12067 22317
1 ,3-beta-glucanosyltransferase,
Re01 ■g' 8350 putative 1818 12068 22318 31008 32498
Re01 ■g' 8360 Putative uncharacterized protein 1819 12069 22319
Re01 ■g' 8370 Uncharacterized protein 1820 12070 22320
Re01 ■g' 8380 Uncharacterized protein 1821 12071 22321
Re01 ■g' 8390 Uncharacterized protein 1822 12072 22322 31009 32499
Re01 ■g' 8400 Reverse transcriptase, putative 1823 12073 22323
Vacuolar aspartyl aminopeptidase
Re01 ■g' 8410 Lap4 1824 12074 22324 31010 32500
Re01 ■g' 8420 Integral membrane protein 1825 12075 22325
Proteasome maturation ans
ribosome synthesis protein Nop10,
Re01 ■g' 8430 putative 1826 12076 22326
H/ACA ribonucleoprotein complex
Re01 ■g' 8440 subunit 3 1827 12077 22327
Re01 ■g' 8450 Uncharacterized protein Fragment 1828 12078 22328
Re01 ■g' 8460 Ribosomal protein 1829 12079 22329 3101 1 32501
Long chronological lifespan protein
Re01 ■g' 8470 2 Precursor 1830 12080 22330 31012 32502
Re01 ■g' 8480 Putative uncharacterized protein 1831 12081 22331
Re01 ■g' 8490 Ubiquitin-conjugating enzyme E2- 1832 12082 22332 18 kDa
Meiosis-specific topoisomerase
Re01 ■9' 8500 Spoi l , putative 1833 12083 22333
Re01 ■g' 8510 Oxidosqualene:lanosterol cyclase 1834 12084 22334
Re01 ■g' 8520 SGT1 and CS domain protein 1835 12085 22335
Re01 ■g' 8530 PQ loop repeat protein 1836 12086 22336
Re01 ■g' 8540 Transaldolase EC=2.2.1.2 1837 12087 22337
Re01 ■g' 8550 Cysteinyl-tRNA synthetase 1838 12088 22338
tRNA methyltransferase subunit
Re01 ■g' 8560 GCD14, putative 1839 12089 22339
Re01 ■g' 8570 UBA/TS-N domain protein 1840 12090 22340
Re01 ■g' 8580 Conserved fungal protein 1841 12091 22341
Re01 ■g' 8590 Small monomeric GTPase 1842 12092 22342
Re01 ■g' 8600 Predicted protein 1843 12093 22343
Adaptor complexes medium
Re01 ■g' 8610 subunit family protein 1844 12094 22344
Re01 ■g' 8620 RNase III domain protein 1845 12095 22345
Succinate dehydrogenase
Re01 ■g' 8630 cytochrome b560 subunit 1846 12096 22346
BZIP transcription factor (HapX),
Re01 ■g' 8640 putative 1847 12097 22347
Glutathione-dependent
Re01 ■g' 8650 formaldehyde dehydrogenase 1848 12098 22348
Mitochondrial 54S ribosomal
Re01 ■g' 8660 protein IMG1 1849 12099 22349
Re01 ■g' 8670 Putative uncharacterized protein 1850 12100 22350
Re01 ■g' 8680 Uncharacterized protein 1851 12101 22351
Re01 ■g' 8690 Putative uncharacterized protein 1852 12102 22352
Re01 ■g' 8700 Pc22g14360 protein Precursor 1853 12103 22353 31013 32503
DNA damage response protein
Re01 ■g' 8710 Rtt109, putative 1854 12104 22354
Ceramide glucosyltransferase,
Re01 ■g' 8720 putative 1855 12105 22355 31014 32504
Ankyrin repeat protein (Yar1 ),
Re01 ■g' 8730 putative 1856 12106 22356
Re01 ■g' 8740 WW domain protein 1857 12107 22357
Re01 ■g' 8750 Conidial hydrophobin Hyp1/RodA 1858 12108 22358 31015 32505
Re01 ■g' 8760 hypothetical protein 1859 12109 22359 31016 32506
2-nitropropane dioxygenase family
Re01 ■g' 8770 oxidoreductase, putative 1860 121 10 22360
Re01 ■g' 8780 Uncharacterized protein 1861 121 1 1 22361
Mitochondrial fusion protein
Re01 ■g' 8790 (Ugo1 ), putative 1862 121 12 22362
2Fe-2S iron-sulfur cluster binding
Re01 ■g' 8800 domain protein 1863 121 13 22363
Re01 ■g' 8810 Pc22g 13900 protein 1864 121 14 22364
Signal recognition particle protein
Re01 ■g' 8820 SRP54 1865 121 15 22365
Re01 ■g' 8830 Alkaline phosphatase family protein 1866 121 16 22366 31017 32507 Class III chitinase, putative
Re01.g18840 EC=3.2.1.14 1867 121 17 22367
Re01.g18850 Putative uncharacterized protein 1868 121 18 22368 31018 32508
Re01.g18860 hypothetical protein 1869 121 19 22369
Re01.g18870 Uncharacterized protein 1870 12120 22370
Similarity to hypothetical protein
Re01.g18880 AAH28592.1 1871 12121 22371
Isopenicillin N-CoA epimerase,
Re01.g18890 putative EC=5.1.99.4 1872 12122 22372
Re01.g18900 WW domain protein 1873 12123 22373
Re01.g18910 Gibberellin 20-oxidase, putative 1874 12124 22374
Re01.g18920 Chitinase 1875 12125 22375 31019 32509
Re01.g18930 Uncharacterized protein 1876 12126 22376 31020 32510
Spindle pole body associated
Re01.g18940 protein SnaD, putative 1877 12127 22377
Conidiation-specific protein Con-
Re01.g18950 10, putative 1878 12128 22378 31021 3251 1
Re01.g18960 Tyrosinase, putative 1879 12129 22379 31022 32512
Re01.g18970 Uncharacterized protein 1880 12130 22380
Re01.g18980 hypothetical protein 1881 12131 22381
Re01.g18990 Pc17g00310 protein 1882 12132 22382
Phosphotransferase enzyme family
Re01.g19000 protein 1883 12133 22383
Re01.g19010 Predicted protein 1884 12134 22384
Retrotransposable element Tf2
Re01.g19020 protein type 1 -like protein 1885 12135 22385
Re01.g19030 Uncharacterized protein 1886 12136 22386
Re01.g19040 Putative uncharacterized protein 1887 12137 22387
Re01.g19050 Uncharacterized protein 1888 12138 22388
Re01.g19060 Putative uncharacterized protein 1889 12139 22389
Re01.g19070 Uncharacterized protein 1890 12140 22390
Re01.g19080 Uncharacterized protein 1891 12141 22391 31023 32513
Re01.g19090 Uncharacterized protein 1892 12142 22392
MYB DNA-binding domain-
Re01.g19100 containing protein 1893 12143 22393
Re01.g191 10 hypothetical protein 1894 12144 22394
Re01.g19120 Pc17g00310 protein 1895 12145 22395
Re01.g19130 Putative uncharacterized protein 1896 12146 22396
Re01.g19140 Putative uncharacterized protein 1897 12147 22397
Re01.g19150 Putative uncharacterized protein 1898 12148 22398
Re01.g19160 Putative uncharacterized protein 1899 12149 22399
Re01.g19170 Predicted protein 1900 12150 22400
Re01.g19180 Uncharacterized protein 1901 12151 22401
Re01.g19190 Uncharacterized protein 1902 12152 22402
Re01.g19200 Putative uncharacterized protein 1903 12153 22403
Re01.g19210 Uncharacterized protein 1904 12154 22404
Re01.g19220 hypothetical protein 1905 12155 22405 31024 32514
Re01.g19230 Uncharacterized protein 1906 12156 22406 31025 32515
Re01.g19240 CRAL/TRIO domain protein 1907 12157 22407 Transcription initiation factor TFIID
Re01.g19250 complex 60 kDa subunit 1908 12158 22408
S-adenosylmethionine
Re01.g19260 decarboxylase proenzyme 1909 12159 22409
Transcription initiation factor TFIID
Re01.g19270 subunit beta 1910 12160 22410
Re01.g19280 Salicylate hydroxylase 191 1 12161 2241 1
Re01.g19290 hypothetical protein 1912 12162 22412
Re01.g19300 Uncharacterized protein 1913 12163 22413
Re01.g19310 Uncharacterized protein 1914 12164 22414
Re01.g19320 Putative uncharacterized protein 1915 12165 22415
Re01.g19330 Putative uncharacterized protein 1916 12166 22416
Re01.g19340 Putative uncharacterized protein 1917 12167 22417
Re01.g19350 hypothetical protein 1918 12168 22418
Mitochondrial export translocase
Re01.g19360 Oxa1 , putative 1919 12169 22419
Re01.g19370 Putative uncharacterized protein 1920 12170 22420
Cdc48-dependent protein
degradation adaptor protein
Re01.g19380 (Shp1 ), putative 1921 12171 22421
Re01.g19390 hypothetical protein 1922 12172 22422 31026 32516
Re01.g19400 Uncharacterized protein 1923 12173 22423 31027 32517
Re01.g19410 Putative uncharacterized protein 1924 12174 22424
Re01.g19420 Predicted protein 1925 12175 22425 31028 32518
Re01.g19430 hypothetical protein 1926 12176 22426
Re01.g19440 Nucleotide binding protein, putative 1927 12177 22427
Re01.g19450 Uncharacterized protein 1928 12178 22428
Re01.g19460 Uncharacterized protein Fragment 1929 12179 22429
Mitochondrial large ribosomal
Re01.g19470 subunit protein L1 1930 12180 22430
Similarity to several cytosolic
glutamate-tRNA ligases from
different species EC=6.1.1.18
Re01.g19480 Precursor 1931 12181 22431 31029 32519
Hydrophobic surface binding
Re01.g19490 protein A 1932 12182 22432 31030 32520
Re01.g19500 Putative uncharacterized protein 1933 12183 22433 31031 32521
Re01.g19510 Serum paraoxonase/arylesterase 2 1934 12184 22434
Re01.g19520 hypothetical protein 1935 12185 22435
Plasma membrane H()ATPase,
Re01.g19530 putative EC=3.6.3.6 1936 12186 22436
Glutathione-dependent
Re01.g19540 formaldehyde-activating 1937 12187 22437
Re01.g19550 Class III chitinase, putative 1938 12188 22438 31032 32522
Re01.g19560 Putative uncharacterized protein 1939 12189 22439
Re01.g19570 Putative uncharacterized protein 1940 12190 22440
Re01.g19580 HypA-like protein, putative 1941 12191 22441
Aldehyde reductase (AKR1 ),
Re01.g19590 putative 1942 12192 22442 TFIIH complex helicase Ssl2,
Re01 ■9' 9600 putative 1943 12193 22443
Re01 ■g' 9610 Putative uncharacterized protein 1944 12194 22444
Similarity to EST SEQ ID NO:6052
Re01 ■g' 9620 from patent WO200056762-A2 1945 12195 22445
Re01 ■g' 9630 Putative uncharacterized protein 1946 12196 22446
Re01 ■g' 9640 hypothetical protein 1947 12197 22447 31033 32523
Re01 ■g' 9660 hypothetical protein 1948 12198 22448
Re01 ■g' 9670 Erp2,4 1949 12199 22449 31034 32524
Re01 ■g' 9680 Uncharacterized protein 1950 12200 22450
Pyruvate dehydrogenase kinase,
Re01 ■g' 9690 putative 1951 12201 22451
Re01 ■g' 9700 Uncharacterized protein 1952 12202 22452
Re01 ■g' 9710 Uncharacterized protein 1953 12203 22453
Microsomal signal peptidase
Re01 ■g' 9720 subunit (Gp23), putative 1954 12204 22454
Disease resistance protein Aig2,
Re01 ■g' 9730 putative 1955 12205 22455
Re01 ■g' 9740 Ulp1 protease, putative 1956 12206 22456
Translation initiation factor elF4E3,
Re01 ■g' 9750 putative 1957 12207 22457
Re01 ■g' 9760 Putative uncharacterized protein 1958 12208 22458
Re01 ■g' 9770 Pc21 g16030 protein 1959 12209 22459 31035 32525
Re01 ■g' 9780 Putative uncharacterized protein 1960 12210 22460
Conidial pigment polyketide
Re01 ■g' 9790 synthase PksP/Alb1 1961 1221 1 22461
Conidial pigment biosynthesis
Re01 ■g' 9800 oxidase Arb2/brown2 1962 12212 22462 31036 32526
SH3 domain protein (Cyk3),
Re01 ■g' 9810 putative 1963 12213 22463
Re01 ■g' 9820 Uncharacterized protein 1964 12214 22464
PHD transcription factor (Rum1 ),
Re01 ■g' 9830 putative 1965 12215 22465
Structure-specific endonuclease
Re01 ■g' 9840 subunit slx1 EC=3.6.1.- 1966 12216 22466
Re01 ■g' 9850 Thymidylate kinase 1967 12217 22467
tRNA-guanine transglycosylase
Re01 ■g' 9860 family protein 1968 12218 22468
Re01 ■g' 9870 Uncharacterized protein 1969 12219 22469
Re01 ■g' 9880 Uncharacterized protein 1970 12220 22470
Nucleoside diphosphate kinase
Re01 ■g' 9890 EC=2.7.4.6 1971 12221 22471
Alpha glucosidase II, alpha subunit,
Re01 ■g' 9900 putative EC=3.2.1.84 1972 12222 22472 31037 32527
Re01 ■g' 9910 PQ loop repeat protein 1973 12223 22473 31038 32528
Re01 ■g' 9920 Putative uncharacterized protein 1974 12224 22474
Re01 ■g' 9930 hypothetical protein 1975 12225 22475
Glutamine-dependent NAD(+)
Re01.g19940 synthetase 1976 12226 22476 31039 32529 Re01.g19950 NADH pyrophosphatase, putative 1977 12227 22477
Re01.g19960 Protein kinase, putative 1978 12228 22478 31040 32530
Re01.g19970 Putative uncharacterized protein 1979 12229 22479
Re01.g19980 GTP cyclohydrolase I 1980 12230 22480
Putative uncharacterized protein
Re01.g19990 An09g05300 1981 12231 22481
Re01.g20000 Exonuclease Kem1 , putative 1982 12232 22482
Re01.g20010 MFS transporter, putative 1983 12233 22483
Similarity to hypothetical protein
Re01.g20020 CAE76169.1 1984 12234 22484
Re01.g20030 Uncharacterized protein 1985 12235 22485 31041 32531
Re01.g20040 WD repeat protein 1986 12236 22486
Re01.g20050 Septin 1987 12237 22487
Small nucleolar ribonucleoprotein
Re01.g20060 complex subunit (Pwp2), putative 1988 12238 22488
Re01.g20070 Uncharacterized protein 1989 12239 22489 31042 32532
Re01.g20080 Putative uncharacterized protein 1990 12240 22490
Re01.g20090 Putative uncharacterized protein 1991 12241 22491 31043 32533
Transcriptional regulator
Re01.g20100 Cwf13/SkiP, putative 1992 12242 22492
Re01.g201 10 DnaJ domain protein 1993 12243 22493
Re01.g20120 Putative uncharacterized protein 1994 12244 22494
Re01.g20130 Putative uncharacterized protein 1995 12245 22495
Re01.g20140 Uncharacterized protein 1996 12246 22496
Re01.g20150 Uncharacterized protein 1997 12247 22497
Re01.g20160 60S ribosomal protein L4 1998 12248 22498
Re01.g20170 Uncharacterized protein 1999 12249 22499
Re01.g20180 Uncharacterized protein 2000 12250 22500 31044 32534
Re01.g20190 hypothetical protein 2001 12251 22501
Re01.g20200 hypothetical protein 2002 12252 22502
Re01.g20210 Putative uncharacterized protein 2003 12253 22503
Re01.g20220 Impact family protein 2004 12254 22504
Aromatic amino acid
Re01.g20230 aminotransferase 2005 12255 22505
Re01.g20240 LCCL domain protein 2006 12256 22506
Re01.g20250 Predicted protein 2007 12257 22507
Re01.g20260 Putative uncharacterized protein 2008 12258 22508
Re01.g20270 SNARE domain protein 2009 12259 22509
Re01.g20280 Uncharacterized protein 2010 12260 22510
Re01.g20290 hypothetical protein 201 1 12261 2251 1 31045 32535
Putative uncharacterized protein
Re01.g20300 An09g04910 2012 12262 22512
Lysophospholipase, putative
Re01.g20310 EC=3.1.1.47 2013 12263 22513
Putative high affinity methionine
Re01.g20320 permease protein 2014 12264 22514
Re01.g20330 Uncharacterized protein 2015 12265 22515 31046 32536
Re01.g20340 Uncharacterized protein 2016 12266 22516
Re01.g20350 hypothetical protein 2017 12267 22517 31047 32537 Glycoside hydrolase family 18
Re01.g20360 protein 2018 12268 22518 31048 32538
Re01.g20370 Putative uncharacterized protein 2019 12269 22519 31049 32539
Re01.g20380 Uncharacterized protein 2020 12270 22520
Re01.g20390 Methyltransferase, putative 2021 12271 22521
Putative nad dependent epimerase
Re01.g20400 dehydratase protein 2022 12272 22522
Re01.g20410 Serine palmitoyltransferase 2 2023 12273 22523
Re01.g20420 Putative uncharacterized protein 2024 12274 22524 31050 32540
Re01.g20430 hypothetical protein 2025 12275 22525
Re01.g20440 Citrate synthase EC=2.3.3.1 2026 12276 22526
Re01.g20450 Pc22g07740 protein 2027 12277 22527
Re01.g20460 Putative mfs protein 2028 12278 22528
Re01.g20470 Uncharacterized protein 2029 12279 22529 31051 32541
Re01.g20480 Related to methyltransferase 2030 12280 22530
Re01.g20490 Aldo/keto reductase, putative 2031 12281 22531
Re01.g20500 Uncharacterized protein 2032 12282 22532
Re01.g20510 Predicted protein 2033 12283 22533 31052 32542
Re01.g20520 MFS sugar transporter, putative 2034 12284 22534
Re01.g20530 Uncharacterized protein 2035 12285 22535
Re01.g20540 Putative uncharacterized protein 2036 12286 22536
Re01.g20550 Integral membrane protein 2037 12287 22537
Re01.g20560 Amino acid permease, putative 2038 12288 22538
Re01.g20570 Uncharacterized protein 2039 12289 22539
Re01.g20580 Uncharacterized protein 2040 12290 22540
Nicotinamide nucleotide
Re01.g20590 transhydrogenase, putative 2041 12291 22541 31053 32543
Re01.g20600 Major facilitator superfamily 2042 12292 22542 31054 32544
Gamma-tubulin complex
Re01.g20610 component GCP5, putative 2043 12293 22543
Alpha-1 ,2 mannosyltransferase
Re01.g20620 KTR1 2044 12294 22544 31055 32545
Cytochrome c oxidase subunit Va,
Re01.g20630 putative 2045 12295 22545
Fatty acid elongase (Gns1),
Re01.g20640 putative 2046 12296 22546
Re01.g20650 Putative uncharacterized protein 2047 12297 22547
Phosphoribosylformylglycinamidine
Re01.g20660 synthase EC=6.3.5.3 2048 12298 22548
Efflux pump antibiotic resistance
Re01.g20670 protein, putative 2049 12299 22549
Re01.g20680 C6 transcription factor, putative 2050 12300 22550
Re01.g20690 hypothetical protein 2051 12301 22551
Re01.g20700 Uncharacterized protein 2052 12302 22552 31056 32546
Endoplasmic reticulum-resident
Re01.g20710 kdel protein 2053 12303 22553 31057 32547
20S cyclosome subunit
Re01.g20720 (Cut9/Cdc16), putative 2054 12304 22554
Re01.g20730 hypothetical protein 2055 12305 22555 Re01.g20740 Uncharacterized protein 2056 12306 22556
Re01.g20750 Transcription-associated protein 2057 12307 22557
Protein phosphatase regulatory
Re01.g20760 subunit (Ssc1 ), putative 2058 12308 22558
RNA polymerase III transcription
Re01.g20770 factor (TF)IIIC subunit 2059 12309 22559
Re01.g20780 Uncharacterized protein 2060 12310 22560
Re01.g20790 Ribokinase 2061 1231 1 22561
DNA replication licensing factor
Re01.g20800 Mcm5, putative 2062 12312 22562
GARP complex component
Re01.g20810 (Vps54), putative 2063 12313 22563
Re01.g20820 hypothetical protein 2064 12314 22564
Re01.g20830 Uncharacterized protein 2065 12315 22565
Re01.g20840 Uncharacterized protein 2066 12316 22566
Re01.g20850 Uncharacterized protein 2067 12317 22567
Zinc-binding oxidoreductase,
Re01.g20860 putative 2068 12318 22568
Re01.g20870 Glycogen synthase Gsy1 , putative 2069 12319 22569
Thiamine biosynthesis protein
Re01.g20880 (Nmt1 ), putative 2070 12320 22570
Re01.g20890 Uncharacterized protein Fragment 2071 12321 22571 31058 32548
Re01.g20900 Uncharacterized protein 2072 12322 22572
Re01.g20910 20S cyclosome subunit 2073 12323 22573
Re01.g20920 hypothetical protein 2074 12324 22574
ATP dependent DNA ligase
Re01.g20930 domain protein 2075 12325 22575
Splicing factor 3a subunit 3,
Re01.g20940 putative 2076 12326 22576
Eukaryotic translation initiation
Re01.g20950 factor elF-4A subunit, putative 2077 12327 22577
Re01.g20970 F-box domain protein 2078 12328 22578
Re01.g20980 Putative uncharacterized protein 2079 12329 22579
Re01.g20990 Ankyrin repeat protein 2080 12330 22580
Re01.g21010 Carnitinyl-CoA dehydratase 2081 12331 22581
Re01.g21020 Putative uncharacterized protein 2082 12332 22582
Re01.g21030 4-coumarate-CoA ligase 2083 12333 22583
Endo-1 ,3(4)-beta-glucanase,
Re01.g21040 putative 2084 12334 22584
Re01.g21050 Putative uncharacterized protein 2085 12335 22585
Re01.g21060 hypothetical protein 2086 12336 22586
Re01.g21070 Uncharacterized protein 2087 12337 22587
Re01.g21080 Glycoside hydrolase, putative 2088 12338 22588 31059 32549
Re01.g21090 Putative uncharacterized protein 2089 12339 22589
Potassium ion transporter (Trk1 ),
Re01.g21 100 putative 2090 12340 22590 31060 32550
Monocarboxylate transporter,
Re01.g21 1 10 putative 2091 12341 22591
Re01.g21 120 Hydrolase, carbon-nitrogen family, 2092 12342 22592 putative
Vacuolar dynamin-like GTPase
ReO' .g21 130 VpsA, putative 2093 12343 22593
Vacuolar ATP synthase catalytic
ReO' .g21 140 subunit A, putative 2094 12344 22594
MFS transporter, ACS family,
ReO' .g21 150 allantoate permease 2095 12345 22595
ReO' .g21 160 Uncharacterized protein 2096 12346 22596
ReO' .g21 170 Auxin Efflux Carrier superfamily 2097 12347 22597 31061 32551
ReO' .g21 180 WD40 repeat-containing protein 2098 12348 22598
Inositol polyphosphate
ReO' .g21 190 phosphatase, putative 2099 12349 22599
ReO' .g21200 Putative uncharacterized protein 2100 12350 22600
Proteasome subunit alpha type
ReO' .g21210 EC=3.4.25.1 2101 12351 22601
ReO' .g21220 Uncharacterized protein 2102 12352 22602
ReO' .g21230 RNA binding protein (Arp), putative 2103 12353 22603
Nuclear condensin complex
ReO' .g21240 subunit 3, putative 2104 12354 22604
ReO' .g21250 Cysteine synthase 2105 12355 22605
ReO' .g21260 Sulfite oxidase, putative 2106 12356 22606
ReO' .g21270 Methyltransferase, putative 2107 12357 22607
ReO' .g21280 Putative uncharacterized protein 2108 12358 22608
ReO' .g21290 Putative uncharacterized protein 2109 12359 22609
ReO' .g21300 Uncharacterized protein 21 10 12360 22610
Mitochondrial import inner
membrane translocase subunit
ReO' .g21310 (TIM22), putative 21 1 1 12361 2261 1
ReO' .g21320 Putative uncharacterized protein 21 12 12362 22612 31062 32552
ReO' .g21330 Mst3-like protein kinase, putative 21 13 12363 22613
Podospora anserina S mat+
genomic DNA chromosome 2,
ReO' .g21340 supercontig 2 21 14 12364 22614
ReO' .g21350 Uncharacterized protein 21 15 12365 22615
ReO' .g21360 Uncharacterized protein 21 16 12366 22616
ReO' .g21370 Actin interacting protein 2 21 17 12367 22617 31063 32553
ReO' .g21380 Putative uncharacterized protein 21 18 12368 22618
NAD dependent
epimerase/dehydratase family
ReO' .g21390 protein 21 19 12369 22619
ReO' .g21400 hypothetical protein 2120 12370 22620
ReO' .g21410 Putative uncharacterized protein 2121 12371 22621
ReO' .g21420 UPF0047 domain protein 2122 12372 22622
ReO' .g21430 Uncharacterized protein 2123 12373 22623
ReO' .g21440 Putative uncharacterized protein 2124 12374 22624
Golgi apparatus membrane protein
ReO' .g21450 tvp38 2125 12375 22625
CCCH zinc finger and SMR domain
ReO' .g21460 protein 2126 12376 22626 Re01.g21470 Citrate lyase beta subunit, putative 2127 12377 22627
Clathrin-coated vesicle protein,
Re01 .g21480 putative 2128 12378 22628
Re01 .g21490 Uncharacterized protein 2129 12379 22629
Re01 .g21500 hypothetical protein 2130 12380 22630
Re01 .g21510 Uncharacterized protein 2131 12381 22631
Re01 .g21520 hypothetical protein 2132 12382 22632
Re01 .g21530 Predicted protein 2133 12383 22633
Similarity to hypothetical protein
Re01 .g21540 CAD11379.1 2134 12384 22634
Re01 .g21550 Putative uncharacterized protein 2135 12385 22635
U1 small nuclear ribonucleoprotein
Re01 .g21560 C 2136 12386 22636
Re01 .g21570 Uncharacterized protein 2137 12387 22637 31064 32554
ATP-dependent RNA helicase
Re01 .g21580 hasl EC=3.6.4.13 2138 12388 22638
Re01 .g21590 Putative uncharacterized protein 2139 12389 22639
Metallo-beta-lactamase family
Re01 .g21600 protein 2140 12390 22640
Re01 .g21610 hypothetical protein 2141 12391 22641 31065 32555
HAD superfamily hydrolase,
Re01 .g21620 putative 2142 12392 22642
Re01 .g21630 Zinc knuckle domain protein 2143 12393 22643
Unfolded protein response protein
Re01 .g21640 Orm1 , putative 2144 12394 22644
Re01 .g21650 Uncharacterized protein 2145 12395 22645
Re01 .g21660 Calponin homology domain protein 2146 12396 22646
Re01 .g21670 Putative uncharacterized protein 2147 12397 22647
Alpha-ketoglutarate-dependent
Re01 .g21680 sulfonate dioxygenase, putative 2148 12398 22648
Re01 .g21690 Uncharacterized protein 2149 12399 22649
Re01 .g21700 Uncharacterized protein 2150 12400 22650
Re01 .g21710 hypothetical protein 2151 12401 22651
Re01 .g21720 Putative uncharacterized protein 2152 12402 22652
Endosomal cargo receptor (Erv25),
Re01 .g21730 putative 2153 12403 22653 31066 32556
Re01 .g21740 Putative uncharacterized protein 2154 12404 22654
Re01 .g21750 Uncharacterized protein 2155 12405 22655
Succinate dehydrogenase
Re01 .g21760 assembly factor 2 2156 12406 22656
Re01 .g21770 Vitamin H transporter, putative 2157 12407 22657
Plasma membrane protein Pth 11-
Re01 .g21780 like, putative 2158 12408 22658
Re01 .g21790 Acetolactate synthase, putative 2159 12409 22659
G-protein complex beta subunit
Re01 .g21800 CpcB 2160 12410 22660
Re01 .g21810 TPR domain protein 2161 12411 22661
Re01 .g21820 DUF159 domain protein 2162 12412 22662
Re01 .g21830 Putative uncharacterized protein 2163 12413 22663 Re01.g21840 Uncharacterized protein 2164 12414 22664
Re01 .g21850 Glutamine synthetase EC=6.3.1.2 2165 12415 22665
Re01 .g21860 Putative uncharacterized protein 2166 12416 22666
MFS monosaccharide transporter,
Re01 .g21870 putative 2167 12417 22667
Zinc knuckle transcription factor
Re01 .g21880 (CnjB), putative 2168 12418 22668
Re01 .g21890 Putative uncharacterized protein 2169 12419 22669
3-hydroxyacyl-CoA dehyrogenase,
Re01 .g21900 putative 2170 12420 22670 31067 32557
Re01 .g21910 Actin-related protein ArpA 2171 12421 22671
Glycosyltransferase family 28,
Re01 .g21920 putative 2172 12422 22672
Re01 .g21930 Uncharacterized protein Fragment 2173 12423 22673
Re01 .g21940 Uncharacterized protein 2174 12424 22674
Re01 .g21950 Uncharacterized protein 2175 12425 22675
Re01 .g21960 Uncharacterized protein 2176 12426 22676 31068 32558
Chromatin remodeling complex
Re01 .g21970 subunit (Chd3), putative 2177 12427 22677
RNA methyltransferase, TrmH
Re01 .g21980 family 2178 12428 22678 31069 32559
Aspartic endopeptidase (AP1),
Re01 .g21990 putative 2179 12429 22679
SNF2 family helicase/ATPase,
Re01 .g22000 putative 2180 12430 22680
Re01 .g22010 Putative uncharacterized protein 2181 12431 22681
Re01 .g22020 Uncharacterized protein 2182 12432 22682
AP-3 adaptor complex subunit mu,
Re01 .g22030 putative 2183 12433 22683
Re01 .g22040 Aldehyde dehydrogenase 2184 12434 22684
Re01 .g22050 Isocitrate lyase EC=4.1.3.1 2185 12435 22685
Re01 .g22060 Neutral trehalase 2186 12436 22686
Short chain
Re01 .g22070 dehydrogenase/reductase family 2187 12437 22687
Re01 .g22080 Uncharacterized protein 2188 12438 22688
Re01 .g22090 Thiol methyltransferase 2189 12439 22689
MFS multidrug resistance
Re01 .g22100 transporter, putative 2190 12440 22690
Kinetoplast-associated protein-like
Re01 .g22110 protein Fragment 2191 12441 22691
Re01 .g22120 Putative uncharacterized protein 2192 12442 22692
Re01 .g22130 Putative uncharacterized protein 2193 12443 22693
C2H2 finger domain protein,
Re01 .g22140 putative 2194 12444 22694
Re01 .g22150 Putative uncharacterized protein 2195 12445 22695
Re01 .g22160 Uncharacterized protein 2196 12446 22696 31070 32560
Threonyl-tRNA synthetase,
Re01 .g22170 putative 2197 12447 22697
Re01 .g22180 Uncharacterized protein 2198 12448 22698 Re01.g22190 Uncharacterized protein 2199 12449 22699
Re01.g22200 WSC domain protein, putative 2200 12450 22700 31071 32561
Succinyl-CoA:3-ketoacid- coenzyme A transferase (ScoT),
Re01.g22210 putative 2201 12451 22701
Re01.g22220 Putative uncharacterized protein 2202 12452 22702
Re01.g22230 Metal homeostatis protein bsd2 2203 12453 22703
Re01.g22240 Uncharacterized protein 2204 12454 22704
Mitogen-activated protein kinase
Re01.g22250 spm1 2205 12455 22705
Ubiquitin carboxyl-terminal
Re01.g22260 hydrolase, putative 2206 12456 22706
NADH-ubiquinone oxidoreductase
Re01.g22270 213 kDa subunit 2207 12457 22707
Re01.g22280 PH domain protein 2208 12458 22708
Re01.g22290 Uncharacterized protein 2209 12459 22709
Re01.g22300 Putative uncharacterized protein 2210 12460 22710
Similarity: the ORF is much shorter
than igA of N. meningitidis
Re01.g22310 Precursor 2211 12461 22711
Re01.g22320 WD domain protein 2212 12462 22712
GTPase activating protein
Re01.g22330 (BUD2/CLA2), putative 2213 12463 22713
Re01.g22340 Autophagy protein Apg9, putative 2214 12464 22714
Re01.g22350 Class I alpha-mannosidase 1A 2215 12465 22715
Re01.g22360 Putative uncharacterized protein 2216 12466 22716
Re01.g22370 Pc16g 11450 protein 2217 12467 22717
Cell wall glucanase (Scw4),
Re01.g22380 putative 2218 12468 22718 31072 32562
Serine palmitoyl CoA transferase
Re01.g22390 subunit LcbA EC=2.3.1.50 2219 12469 22719
Re01.g22400 Uncharacterized protein 2220 12470 22720
1 ,3-beta-glucan synthase catalytic
Re01.g22410 subunit FksP 2221 12471 22721
Re01.g22430 Uncharacterized protein 2222 12472 22722 31073 32563
Re01.g22440 Uncharacterized protein 2223 12473 22723
Re01.g22450 Uncharacterized protein 2224 12474 22724
Re01.g22460 Uncharacterized protein 2225 12475 22725
Re01.g22470 Uncharacterized protein 2226 12476 22726
Ran-interacting protein Mog1 ,
Re01.g22480 putative 2227 12477 22727
Re01.g22490 Putative uncharacterized protein 2228 12478 22728
Chaperone/heat shock protein
Re01.g22500 Hsp12, putative 2229 12479 22729
Re01.g22510 Uncharacterized protein 2230 12480 22730
Golgi transport complex subunit
Re01.g22520 Cog6, putative 2231 12481 22731
NGG1 interacting factor Nif3,
Re01.g22530 putative 2232 12482 22732 Re01.g22540 BolA domain protein 2233 12483 22733
Re01.g22550 AhpC/TSA family protein 2234 12484 22734 31074 32564
Stress response regulator/HFS
Re01.g22560 transcription factor, putative 2235 12485 22735
Translation initiation factor eif-2b
Re01.g22570 epsilon subunit, putative 2236 12486 22736
Re01.g22580 RING finger protein 2237 12487 22737
Re01.g22590 Putative uncharacterized protein 2238 12488 22738
Mitochondrial carrier protein,
Re01.g22600 putative 2239 12489 22739
AAA family ATPase, putative
Re01.g22610 EC=3.6.4.3 2240 12490 22740
Re01.g22620 Uncharacterized protein 2241 12491 22741
Re01.g22630 Putative uncharacterized protein 2242 12492 22742 31075 32565
Alpha.alpha-trehalose-phosphate
Re01.g22640 synthase 1 2243 12493 22743
Metallo-beta-lactamase domain
Re01.g22650 protein, putative 2244 12494 22744
Mitochondrial aconitate hydratase,
Re01.g22660 putative EC=4.2.1.3 2245 12495 22745
Re01.g22670 Putative uncharacterized protein 2246 12496 22746
DsDNA-dependent ATPase Rad54,
Re01.g22680 putative 2247 12497 22747
Re01.g22690 Mitochondrial carrier protein 2248 12498 22748
Vacuole-associated enzyme
activator complex component
Re01.g22700 (Vac14), putative 2249 12499 22749
2-dehydropantoate 2-reductase
Re01.g22710 EC=1.1.1.169 2250 12500 22750
Re01.g22720 Uncharacterized protein 2251 12501 22751
Iron-sulfur clusters transporter
Re01.g22730 atml 2252 12502 22752
Altered inheritance of mitochondria
Re01.g22740 protein 24, mitochondrial Precursor 2253 12503 22753 31076 32566
Re01.g22750 Uncharacterized protein 2254 12504 22754
Re01.g22760 Kinesin family protein 2255 12505 22755
Protein transport protein Sec24,
Re01.g22770 putative EC=2.7.11.24 2256 12506 22756
Re01.g22780 MAP kinase MpkB 2257 12507 22757
Re01.g22790 Uroporphyrinogen-lll synthase 2258 12508 22758
NADH-ubiquinone oxidoreductase
Re01.g22800 39 kDa subunit, putative 2259 12509 22759 31077 32567
Re01.g22810 Putative uncharacterized protein 2260 12510 22760
Proteasome regulatory particle
Re01.g22820 subunit (Rpnl), putative 2261 12511 22761
Re01.g22830 Predicted protein Fragment 2262 12512 22762
Re01.g22840 Rhomboid protein 2 2263 12513 22763 31078 32568
Re01.g22850 Uncharacterized protein 2264 12514 22764
Re01.g22860 Uncharacterized protein 2265 12515 22765
Re01.g22870 Integral membrane protein 2266 12516 22766 31079 32569 Ubiquitin C-terminal hydrolase
Re01.g22880 Ubp8, putative 2267 12517 22767
Re01.g22890 DASH complex subunit Dam1 2268 12518 22768
Re01.g22900 CRAL/TRIO domain protein 2269 12519 22769
Re01.g22910 HIT domain protein 2270 12520 22770
Re01.g22920 Putative uncharacterized protein 2271 12521 22771 31080 32570
Re01.g22930 Beta-alanine synthase, putative 2272 12522 22772
40S ribosomal protein S10-B,
Re01.g22940 putative 2273 12523 22773
Re01.g22950 Putative uncharacterized protein 2274 12524 22774 31081 32571
Re01.g22960 EH domain binding protein epsin 2 2275 12525 22775
Anthranilate synthase component I,
Re01.g22970 putative EC=5.1.3.1 2276 12526 22776
Re01.g22980 Putative uncharacterized protein 2277 12527 22777
Re01.g22990 WD repeat protein 2278 12528 22778
Re01.g23000 Rhomboid family protein 2279 12529 22779 31082 32572
Re01.g23010 50S ribosomal protein Mrp49 2280 12530 22780
Re01.g23020 Leucyl-tRNA synthetase 2281 12531 22781 31083 32573
Putative uncharacterized protein
Re01.g23030 An06g01840 EC=3.5.99.7 2282 12532 22782
Re01.g23040 Putative uncharacterized protein 2283 12533 22783
Re01.g23050 Uncharacterized protein 2284 12534 22784
Re01.g23060 Nuclear distribution protein PAC1 2285 12535 22785
Spindle pole body component,
Re01.g23070 putative 2286 12536 22786
Re01.g23080 60S ribosomal protein L8 2287 12537 22787
GTP binding protein (EngB),
Re01.g23090 putative 2288 12538 22788
DEAD/DEAH box DNA helicase
Re01.g23100 (Mer3), putative 2289 12539 22789
Re01.g231 10 Udp-galactose transporter 2290 12540 22790
Re01.g23120 Putative uncharacterized protein 2291 12541 22791
Re01.g23130 Putative uncharacterized protein 2292 12542 22792
Re01.g23140 Cell division control protein Cdc4 2293 12543 22793
Re01.g23150 Leucine rich repeat protein 2294 12544 22794
Magnesium dependent
Re01.g23160 phosphatase, putative 2295 12545 22795
Transferase hexapeptide domain
Re01.g23170 protein 2296 12546 22796
Filament-forming protein
Re01.g23180 (Tpr/p270), putative 2297 12547 22797
Re01.g23190 Putative uncharacterized protein 2298 12548 22798
3,4-dihydroxy-2-butanone 4-
Re01.g23200 phosphate synthase EC=4.1.99.12 2299 12549 22799
Re01.g23210 Putative uncharacterized protein 2300 12550 22800
Serine/threonine protein kinase,
Re01.g23220 putative 2301 12551 22801
Ubiquitin conjugating enzyme
Re01.g23230 (UbcK), putative 2302 12552 22802 Re01.g23240 H+/nucleoside cotransporter 2303 12553 22803
Re01.g23250 hypothetical protein 2304 12554 22804
CECR1 family adenosine
Re01.g23260 deaminase, putative 2305 12555 22805
Autophagy regulatory protein Atg2,
Re01.g23270 putative 2306 12556 22806
Re01.g23280 hypothetical protein 2307 12557 22807
Re01.g23290 Uncharacterized protein 2308 12558 22808
Re01.g23300 Uncharacterized protein 2309 12559 22809 31084 32574
Re01.g23310 Putative uncharacterized protein 2310 12560 22810 31085 32575
Re01.g23320 60S ribosomal protein L31 231 1 12561 2281 1
Re01.g23330 RanBPI domain protein 2312 12562 22812
Re01.g23340 Putative uncharacterized protein 2313 12563 22813
Re01.g23360 Uncharacterized protein 2314 12564 22814
Re01.g23370 Uncharacterized protein 2315 12565 22815
Re01.g23380 Uncharacterized protein 2316 12566 22816
Putative gtp-binding nuclear protein
Re01.g23390 gspl ran protein 2317 12567 22817
26S proteasome non-ATPase
Re01.g23400 regulatory subunit Nas2, putative 2318 12568 22818
Re01.g23410 Uncharacterized protein 2319 12569 22819
Re01.g23420 RNA binding protein, putative 2320 12570 22820
Uracil DNA glycosylase
Re01.g23430 superfamily protein 2321 12571 22821
Re01.g23440 Putative uncharacterized protein 2322 12572 22822 31086 32576
Re01.g23450 NADPH oxidase (NoxA), putative 2323 12573 22823
Re01.g23460 Uncharacterized protein 2324 12574 22824
Re01.g23470 Uncharacterized protein 2325 12575 22825
Re01.g23480 Putative uncharacterized protein 2326 12576 22826
Re01.g23490 Urea active transporter, putative 2327 12577 22827
Arrestin (Or S-antigen), N-terminal
Re01.g23500 domain protein 2328 12578 22828
Re01.g23510 Tat pathway signal sequence 2329 12579 22829
Re01.g23520 Uncharacterized protein AN0679 2330 12580 22830
Pyridine nucleotide-disulfide
Re01.g23530 oxidoreductase class-2 2331 12581 22831 31087 32577
Re01.g23540 Uncharacterized protein 2332 12582 22832
Choline sulfatase, putative
Re01.g23550 EC=3.1.6.6 2333 12583 22833
Multispanning membrane protein,
Re01.g23560 putative 2334 12584 22834 31088 32578
Ubiquitin-like protein DskB,
Re01.g23570 putative 2335 12585 22835
Nuclear mRNA splicing factor,
Re01.g23580 putative 2336 12586 22836
Phosphotransferase enzyme family
Re01.g23590 protein 2337 12587 22837
Re01.g23600 Nitrilase 2338 12588 22838
Re01.g23610 hypothetical protein 2339 12589 22839 Re01.g23620 Uncharacterized protein 2340 12590 22840
Re01.g23630 Putative uncharacterized protein 2341 12591 22841
Re01.g23640 Putative uncharacterized protein 2342 12592 22842
Re01.g23650 Putative uncharacterized protein 2343 12593 22843
Re01.g23660 Putative uncharacterized protein 2344 12594 22844
Glutamate decarboxylase
Re01.g23670 EC=4.1.1.15 2345 12595 22845
Re01.g23680 hypothetical protein 2346 12596 22846
SIR2 family histone deacetylase,
Re01.g23690 putative 2347 12597 22847
Similarity to hypothetical protein
Re01.g23700 SPAC57A7.05 2348 12598 22848
Isoleucyl-tRNA
synthetase .cytoplasmic
Re01.g23710 EC=6.1.1.5 2349 12599 22849
Re01.g23720 O-methyltransferase, putative 2350 12600 22850
Cytochrome P450
Re01.g23730 CYP3/CYP5/CYP6/CYP9 2351 12601 22851 31089 32579
Re01.g23740 Putative uncharacterized protein 2352 12602 22852
Re01.g23750 Putative uncharacterized protein 2353 12603 22853
Re01.g23760 Glyoxalase 2354 12604 22854
Re01.g23770 Uncharacterized protein 2355 12605 22855 31090 32580
Re01.g23780 Uncharacterized protein 2356 12606 22856
Carboxypeptidase CpyA/Prc1 ,
Re01.g23790 putative 2357 12607 22857 31091 32581
Re01.g23800 Ribosomal protein S13 2358 12608 22858
Re01.g23810 Putative uncharacterized protein 2359 12609 22859
Re01.g23820 Putative uncharacterized protein 2360 12610 22860 31092 32582
Re01.g23830 MFS transporter 2361 1261 1 22861
Re01.g23840 Aldehyde dehydrogenase 2362 12612 22862
Similarity to hypothetical protein
Re01.g23850 CAF06101.1 2363 12613 22863 31093 32583
Re01.g23860 Putative uncharacterized protein 2364 12614 22864 31094 32584
Re01.g23870 Uncharacterized protein 2365 12615 22865
Re01.g23880 Uncharacterized protein 2366 12616 22866
Re01.g23890 MFS multidrug transporter, putative 2367 12617 22867
Re01.g23900 C6 finger domain protein, putative 2368 12618 22868
Re01.g23910 PHD finger protein 2369 12619 22869 31095 32585
Re01.g23930 Uncharacterized protein 2370 12620 22870 31096 32586
Re01.g23940 Major facilitator superfamily 2371 12621 22871
Re01.g23950 Putative uncharacterized protein 2372 12622 22872
GTPase activating protein (Evi5),
Re01.g23960 putative 2373 12623 22873
Re01.g23970 DNA to po iso me rase II 2374 12624 22874
APSES transcription factor Xbp1 ,
Re01.g23980 putative 2375 12625 22875
Re01.g23990 Reticulon-like protein 2376 12626 22876
Re01.g24000 Acyl-CoA dehydrogenase NM 2377 12627 22877
Re01.g24010 Inner centromere protein, ARK 2378 12628 22878 binding region protein
Re01.g24020 Putative uncharacterized protein 2379 12629 22879
Re01.g24030 Putative uncharacterized protein 2380 12630 22880
Re01.g24040 Putative uncharacterized protein 2381 12631 22881
Re01.g24050 Putative uncharacterized protein 2382 12632 22882
Re01.g24060 Putative uncharacterized protein 2383 12633 22883
Re01.g24070 Putative uncharacterized protein 2384 12634 22884
Re01.g24080 Putative uncharacterized protein 2385 12635 22885
Pro-apoptotic serine protease
Re01.g24090 nma1 1 1 EC=3.4.21.- 2386 12636 22886
Re01.g24100 hypothetical protein 2387 12637 22887
Re01.g241 10 Putative uncharacterized protein 2388 12638 22888
Re01.g24120 Putative uncharacterized protein 2389 12639 22889
Similar to cytochrome P450
Re01.g24130 monooxygenase 2390 12640 22890 31097 32587
Re01.g24140 hypothetical protein 2391 12641 22891
Re01.g24150 TPR repeat protein 2392 12642 22892
Cation diffusion facilitator family
Re01.g24160 metal ion transporter, putative 2393 12643 22893 31098 32588
Re01.g24170 Uncharacterized protein 2394 12644 22894
Re01.g24180 Uncharacterized protein 2395 12645 22895
Function: Tto1 can transpose
autonomously through reverse
transcription EC=2.7.7.49
EC=2.7.7.49 EC=2.7.7.49
Re01.g24190 EC=2.7.7.49 2396 12646 22896
Re01.g24200 Cytochrome c peroxidase 2397 12647 22897
Re01.g24210 Uncharacterized protein 2398 12648 22898
Re01.g24220 Putative uncharacterized protein 2399 12649 22899
Re01.g24230 Uncharacterized protein 2400 12650 22900
Re01.g24240 Uncharacterized protein 2401 12651 22901
Dehydrogenase with different
Re01.g24250 specificitie 2402 12652 22902
Re01.g24260 Putative uncharacterized protein 2403 12653 22903
Re01.g24270 Cytochrome P450, putative 2404 12654 22904
Re01.g24280 Pc16g 10990 protein 2405 12655 22905
Short-chain dehydrogenase,
Re01.g24290 putative 2406 12656 22906
Re01.g24300 Pc16g 1 1000 protein 2407 12657 22907
Oxidoreductase, short chain
Re01.g24310 dehydrogenase/reductase family 2408 12658 22908
Re01.g24320 Uncharacterized protein 2409 12659 22909
Re01.g24330 CFEM domain-containing protein 2410 12660 22910 31099 32589
Re01.g24340 Predicted protein 241 1 12661 2291 1
Re01.g24350 Flavin carrier protein 2, putative 2412 12662 22912 31 100 32590
Re01.g24360 Putative uncharacterized protein 2413 12663 22913
Re01.g24370 5'-nucleotidase, putative 2414 12664 22914
Re01.g24380 Putative uncharacterized protein 2415 12665 22915
Re01.g24390 Flavin-binding monooxygenase-like 2416 12666 22916 protein
Re01.g24400 Uncharacterized protein 2417 12667 22917
Re01.g24410 Bleomycin hydrolase, putative 2418 12668 22918
Kinesin family protein (Kin A),
Re01.g24420 putative 2419 12669 22919
Ubiquitin-conjugating enzyme E2 2
Re01.g24430 EC=6.3.2.19 2420 12670 22920
Acetyl-CoA-acetyltransferase,
Re01.g24440 putative 2421 12671 22921
Re01.g24450 Zinc transporter (Msc2), putative 2422 12672 22922
Beta-1 ,4-mannosyltransferase
Re01.g24460 (Alg1), putative EC=2.4.1.142 2423 12673 22923 31101 32591
Re01.g24470 Uncharacterized protein 2424 12674 22924
Ubiquitin conjugating enzyme,
Re01.g24480 putative 2425 12675 22925
Re01.g24490 Putative uncharacterized protein 2426 12676 22926
Re01.g24500 Carnitine/acyl carnitine carrier 2427 12677 22927
Re01.g24510 Uncharacterized protein 2428 12678 22928 31102 32592
Re01.g24520 Carboxylesterase EC=3.1.1.1 2429 12679 22929 31103 32593
Re01.g24530 hypothetical protein 2430 12680 22930
U3 small nucleolar
ribonucleoprotein protein Lcp5,
Re01.g24540 putative 2431 12681 22931
Re01.g24550 Uncharacterized protein 2432 12682 22932 31104 32594
Endosomal integral membrane
Re01.g24560 protein (P24a), putative 2433 12683 22933 31105 32595
Re01.g24570 Pc22g00390 protein 2434 12684 22934
Similarity: shows also similarity to
Re01.g24580 N-terminal half of An08g01460 2435 12685 22935
Re01.g24600 hypothetical protein 2436 12686 22936
Putative multicopper oxidase
Re01.g24620 protein 2437 12687 22937
Re01.g24630 Allergen Asp f 15 Precursor 2438 12688 22938 31106 32596
Re01.g24650 Predicted protein 2439 12689 22939
Re01.g24660 Putative uncharacterized protein 2440 12690 22940
Re01.g24670 MFS transporter, putative 2441 12691 22941
Re01.g24680 Integral membrane protein 2442 12692 22942
Re01.g24690 FAD binding domain protein 2443 12693 22943 31107 32597
Putative major facilitator
Re01.g24700 superfamily transporter protein 2444 12694 22944
Re01.g24710 Pol Fragment 2445 12695 22945
Re01.g24720 Putative uncharacterized protein 2446 12696 22946
Transposon-encoded proteins with
Re01.g24730 TYA 2447 12697 22947
Re01.g24740 Uncharacterized protein Fragment 2448 12698 22948
Re01.g24750 Putative uncharacterized protein 2449 12699 22949
Re01.g24760 Retrovirus polyprotein, putative 2450 12700 22950
Gag/polymerase/env polyprotein,
Re01.g24770 putative 2451 12701 22951 Gag/polymerase/env polyprotein,
Re01.g24780 putative 2452 12702 22952
Re02.g00010 Uncharacterized protein 2453 12703 22953
Re02.g00020 Putative uncharacterized protein 2454 12704 22954 31 108 32598
Re02.g00030 Arylsulfotransferase 2455 12705 22955
Re02.g00040 Urea transporter (Dur3), putative 2456 12706 22956
Related to 3-hydroxybutyryl-CoA
Re02.g00050 dehydrogenase 2457 12707 22957
Re02.g00060 Disulfide oxidoreductase, putative 2458 12708 22958
Re02.g00070 Uncharacterized protein 2459 12709 22959
Glycoside hydrolase family 2
Re02.g00080 protein 2460 12710 22960
GNAT family acetyltransferase,
Re02.g00090 putative 2461 1271 1 22961
1 -aminocyclopropane-1-
Re02.g00100 carboxylate oxidase, putative 2462 12712 22962
Nitrilase/cyanide hydratase
Re02.g001 10 conserved site 2463 12713 22963
Re02.g00120 Aldo-keto reductase 2464 12714 22964
Re02.g00130 Proline racemase, putative 2465 12715 22965
Re02.g00140 Uncharacterized protein 2466 12716 22966
Re02.g00150 hypothetical protein 2467 12717 22967 31 109 32599
Re02.g00160 Beta-lactamase family protein 2468 12718 22968
Re02.g00170 Maltose permease, putative 2469 12719 22969
Re02.g00180 Putative uncharacterized protein 2470 12720 22970
Re02.g00190 Putative uncharacterized protein 2471 12721 22971
Re02.g00200 Putative uncharacterized protein 2472 12722 22972 31 1 10 32600
Re02.g00210 Putative uncharacterized protein 2473 12723 22973
Re02.g00220 Putative uncharacterized protein 2474 12724 22974
Re02.g00230 Putative uncharacterized protein 2475 12725 22975
4-oxalocrotonate tautomerase-like
Re02.g00240 protein 2476 12726 22976
Re02.g00250 Pantothenate transporter, putative 2477 12727 22977
Re02.g00260 Uncharacterized protein 2478 12728 22978
Re02.g00270 hypothetical protein 2479 12729 22979
Putative uncharacterized protein
Re02.g00280 An08g 10450 2480 12730 22980
Re02.g00290 Uncharacterized protein 2481 12731 22981
Putative uncharacterized protein
Re02.g00300 Fragment 2482 12732 22982
Re02.g00310 Uncharacterized protein Fragment 2483 12733 22983
Re02.g00320 Uncharacterized protein 2484 12734 22984
Re02.g00330 Uncharacterized protein 2485 12735 22985 31 1 1 1 32601
Re02.g00340 Glycosyl transferase family protein 2486 12736 22986
Re02.g00350 Uncharacterized protein 2487 12737 22987 31 1 12 32602
Re02.g00360 Putative uncharacterized protein 2488 12738 22988
Re02.g00370 Uncharacterized protein 2489 12739 22989
Re02.g00380 Uncharacterized protein 2490 12740 22990
Re02.g00390 MFS transporter, putative 2491 12741 22991 Re02.g00400 Uncharacterized protein Fragment 2492 12742 22992
Re02.g00410 Uncharacterized protein Fragment 2493 12743 22993
Re02.g00420 Putative uncharacterized protein 2494 12744 22994
Re02.g00430 Uncharacterized protein 2495 12745 22995
Re02.g00440 DNA repair protein rad5 Fragment 2496 12746 22996
Re02.g00450 Alcohol dehydrogenase 2497 12747 22997
Re02.g00460 Uncharacterized protein 2498 12748 22998
Re02.g00470 Putative uncharacterized protein 2499 12749 22999
Re02.g00480 Transposase 2500 12750 23000
Re02.g00500 Predicted protein 2501 12751 23001
Re02.g00510 Uncharacterized protein 2502 12752 23002
Re02.g00520 Putative uncharacterized protein 2503 12753 23003 31 1 13 32603
Re02.g00530 Putative uncharacterized protein 2504 12754 23004
Re02.g00540 Uncharacterized protein 2505 12755 23005
Re02.g00550 DUF1275 domain protein 2506 12756 23006
Re02.g00560 C6 transcription factor, putative 2507 12757 23007
Amino-acid N-acetyltransferase
Re02.g00570 subunit Mak10, putative 2508 12758 23008
Re02.g00580 Uncharacterized protein 2509 12759 23009
Re02.g00590 Putative uncharacterized protein 2510 12760 23010
Antigenic mitochondrial protein
Re02.g00600 HSP60, putative 251 1 12761 2301 1
Re02.g00610 Glutathione S-transferase, putative 2512 12762 23012
Re02.g00620 Cofilin 2513 12763 23013
Cytochrome c oxidase polypeptide
5, mitochondrial EC=1.9.3.1
Re02.g00630 Precursor 2514 12764 23014
ATP synthase subunit beta
Re02.g00640 EC=3.6.3.14 2515 12765 23015 31 1 14 32604
Re02.g00650 Putative uncharacterized protein 2516 12766 23016
1 ,4-alpha-glucan-branching
Re02.g00660 enzyme 2517 12767 23017
Re02.g00670 Proline permease PrnB 2518 12768 23018
Re02.g00680 Putative uncharacterized protein 2519 12769 23019
Re02.g00690 Uncharacterized protein 2520 12770 23020
Re02.g00700 Putative alpha-1 ,2-mannosidase 2521 12771 23021 31 1 15 32605
Protein kinase domain-containing
Re02.g00710 protein 2522 12772 23022
Re02.g00720 Uncharacterized protein 2523 12773 23023
Re02.g00730 Pc16g02830 protein 2524 12774 23024
Re02.g00740 Putative uncharacterized protein 2525 12775 23025
Re02.g00750 Ras GTPase Rab1 1 , putative 2526 12776 23026
Re02.g00760 Putative uncharacterized protein 2527 12777 23027
Chromo domain protein Chpl p,
Re02.g00770 putative 2528 12778 23028
Re02.g00780 ATP-dependent Clp protease 2529 12779 23029 31 1 16 32606
Dienelactone hydrolase family
Re02.g00790 protein 2530 12780 23030
Re02.g00800 Magnesium ion transporter (Mrs2), 2531 12781 23031 putative
Actin associated protein Wsp1 ,
Re02.g00810 putative Fragment 2532 12782 23032
Re02.g00820 DNA repair protein RAD1 , putative 2533 12783 23033
Eukaryotic translation initiation
Re02.g00830 factor elF-1 A subunit, putative 2534 12784 23034
Re02.g00840 Uncharacterized protein 2535 12785 23035
Chitin biosynthesis protein (Chs5),
Re02.g00850 putative 2536 12786 23036
Re02.g00860 hypothetical protein 2537 12787 23037 31 1 17 32607
Re02.g00870 hypothetical protein 2538 12788 23038
Re02.g00880 Putative uncharacterized protein 2539 12789 23039
Re02.g00890 Uncharacterized protein 2540 12790 23040
Re02.g00900 Putative uncharacterized protein 2541 12791 23041
Cytochrome P450, putative
Re02.g00910 (Eurofung) 2542 12792 23042
Re02.g00920 hypothetical protein 2543 12793 23043 31 1 18 32608
Re02.g00930 Putative uncharacterized protein 2544 12794 23044
Re02.g00940 Putative transposase Fragment 2545 12795 23045
Gag/polymerase/env polyprotein,
Re02.g00950 putative 2546 12796 23046
Re02.g00960 Putative uncharacterized protein 2547 12797 23047
Re02.g00970 Uncharacterized protein 2548 12798 23048
Re02.g00980 Putative uncharacterized protein 2549 12799 23049
Re02.g00990 Carboxylesterase, putative 2550 12800 23050 31 1 19 32609
Re02.g01000 Putative uncharacterized protein 2551 12801 23051 31 120 32610
Related to integral membrane
Re02.g01010 protein 2552 12802 23052
Gag/polymerase/env polyprotein,
Re02.g01020 putative 2553 12803 23053
RNA-directed DNA polymerase
Re02.g01030 Fragment 2554 12804 23054
Re02.g01040 Putative uncharacterized protein 2555 12805 23055
Re02.g01050 Putative uncharacterized protein 2556 12806 23056
Re02.g01060 Non-ribosomal peptide synthetase 2557 12807 23057
Re02.g01070 hypothetical protein 2558 12808 23058
Re02.g01080 Putative uncharacterized protein 2559 12809 23059
Re02.g01090 Putative uncharacterized protein 2560 12810 23060
Re02.g01 100 Uncharacterized protein 2561 1281 1 23061
Re02.g01 1 10 Putative uncharacterized protein 2562 12812 23062
Re02.g01 120 hypothetical protein 2563 12813 23063
MYB DNA-binding domain-
Re02.g01 130 containing protein 2564 12814 23064
Re02.g01 140 Putative uncharacterized protein 2565 12815 23065
Re02.g01 150 Putative uncharacterized protein 2566 12816 23066
Re02.g01 160 Uncharacterized protein 2567 12817 23067
C-3 sterol dehydrogenase/3-beta-
Re02.g01 170 hydroxysteroid dehydrogenase 2568 12818 23068
Re02.g01 180 Putative uncharacterized protein 2569 12819 23069 Re02.g01 190 Putative uncharacterized protein 2570 12820 23070
Re02.g01200 hypothetical protein 2571 12821 23071
Re02.g01210 Uncharacterized protein 2572 12822 23072
Re02.g01220 Uncharacterized protein 2573 12823 23073
Re02.g01230 Uncharacterized protein 2574 12824 23074
Re02.g01240 Uncharacterized protein 2575 12825 23075
Re02.g01250 Putative uncharacterized protein 2576 12826 23076
Re02.g01260 Putative uncharacterized protein 2577 12827 23077
Re02.g01270 Predicted protein 2578 12828 23078
Re02.g01280 Uncharacterized protein 2579 12829 23079
Re02.g01290 Putative uncharacterized protein 2580 12830 23080
Re02.g01300 Putative uncharacterized protein 2581 12831 23081
Re02.g01310 Pc17g00310 protein 2582 12832 23082
Re02.g01320 Putative uncharacterized protein 2583 12833 23083
Re02.g01330 Uncharacterized protein 2584 12834 23084
Re02.g01340 Acetyltransferase, GNAT family 2585 12835 23085
Re02.g01350 Phosphate:H symporter 2586 12836 23086
Re02.g01360 hypothetical protein 2587 12837 23087
Re02.g01370 Putative uncharacterized protein 2588 12838 23088
Putative uncharacterized protein
Re02.g01380 Fragment 2589 12839 23089
Re02.g01390 Uncharacterized protein 2590 12840 23090
Re02.g01400 Putative uncharacterized protein 2591 12841 23091
Putative uncharacterized protein
Re02.g01410 An12g08800 2592 12842 23092
Phospholipid-translocating P-type
Re02.g01420 ATPase domain-containing protein 2593 12843 23093
Re02.g01430 Uncharacterized protein 2594 12844 23094
Re02.g01440 Pc22g24360 protein EC=3.6.3.6 2595 12845 23095
Re02.g01450 DUF803 domain protein 2596 12846 23096
Re02.g01460 hypothetical protein 2597 12847 23097 31 121 3261 1
Re02.g01470 MCMA 2598 12848 23098
Re02.g01480 Uncharacterized protein 2599 12849 23099
Re02.g01490 Putative uncharacterized protein 2600 12850 23100
Re02.g01500 Putative uncharacterized protein 2601 12851 23101
Putative uncharacterized protein
Re02.g01510 Fragment 2602 12852 23102
Re02.g01520 C6 transcription factor, putative 2603 12853 23103
Transposon-encoded proteins with
Re02.g01530 TYA 2604 12854 23104 31 122 32612
Re02.g01540 Putative uncharacterized protein 2605 12855 23105
Putative copper-translocating p-
Re02.g01550 type atpase protein 2606 12856 23106
Re02.g01560 Similar to An12g08720 2607 12857 23107 31 123 32613
Rab geranylgeranyl transferase
Re02.g01570 escort protein, putative 2608 12858 23108
Peptidyl-prolyl cis-trans isomerase
Re02.g01580 EC=5.2.1.8 2609 12859 23109
Re02.g01590 Signal peptide peptidase, putative 2610 12860 231 10 Re02.g01600 3' exoribonuclease family protein 261 1 12861 231 1 1
Ferric reductase transmembrane
Re02.g01610 component 7 2612 12862 231 12
GNAT family acetyltransferase,
Re02.g01620 putative 2613 12863 231 13
Re02.g01630 SAGA-associated factor 1 1 2614 12864 231 14
Re02.g01640 Pc12g 12330 protein 2615 12865 231 15
Putative major facilitator
Re02.g01650 superfamily protein 2616 12866 231 16
Re02.g01660 C2HC5 finger protein 2617 12867 231 17
Benzoate 4-monooxygenase
Re02.g01670 cytochrome P450 2618 12868 231 18
Peroxisomal membrane protein 2,
Re02.g01680 pxmp2, putative 2619 12869 231 19 31 124 32614
Re02.g01690 Uncharacterized protein 2620 12870 23120 31 125 32615
Re02.g01700 Glucokinase GlkA, putative 2621 12871 23121
Re02.g01710 Putative uncharacterized protein 2622 12872 23122
Ribonuclease P complex subunit
Re02.g01720 Pop1 , putative 2623 12873 23123
Re02.g01730 Peroxiredoxin pmp20 2624 12874 23124
Re02.g01740 Putative uncharacterized protein 2625 12875 23125
Serine/threonine protein kinase
Re02.g01750 (Kcc4), putative 2626 12876 23126
Re02.g01760 C6 transcription factor, putative 2627 12877 23127
Re02.g01770 hypothetical protein 2628 12878 23128
Re02.g01780 Putative uncharacterized protein 2629 12879 23129 31 126 32616
Re02.g01790 DUF207 domain protein 2630 12880 23130
Re02.g01800 Putative uncharacterized protein 2631 12881 23131
ARP2/3 complex 20 kDa subunit,
Re02.g01810 putative 2632 12882 23132 31 127 32617
Ubiquitin carboxyl-terminal
Re02.g01820 hydrolase EC=3.4.19.12 2633 12883 23133
Re02.g01830 Thioesterase family protein 2634 12884 23134
Re02.g01840 MFS drug efflux pump, putative 2635 12885 23135 31 128 32618
Re02.g01850 WD repeat protein 2636 12886 23136
Ubiquitin conjugating enzyme
Re02.g01860 (UbcM), putative 2637 12887 23137
Re02.g01870 Uncharacterized protein 2638 12888 23138
Re02.g01880 Ribosomal S30/ubiquitin fusion 2639 12889 23139
Glucosamine 6-phosphate
Re02.g01890 acetyltransferase, putative 2640 12890 23140
Re02.g01900 Uncharacterized protein 2641 12891 23141 31 129 32619
Re02.g01910 Flavoprotein 2642 12892 23142
Re02.g01920 Putative uncharacterized protein 2643 12893 23143
Re02.g01930 Uncharacterized protein 2644 12894 23144
Similarity to Sulfolobus solfataricus
esterase P1 -8LC patent
Re02.g01940 WO9730160-A1 EC=3.1.1.- 2645 12895 23145
Re02.g01950 Aspartate transaminase, putative 2646 12896 23146 EC=2.6.1.1
Re02.g01960 Endo-beta-1 ,6-glucanase, putative 2647 12897 23147 31 130 32620
Re02.g01970 Putative uncharacterized protein 2648 12898 23148
Re02.g01980 hypothetical protein 2649 12899 23149
Re02.g01990 hypothetical protein 2650 12900 23150 31 131 32621
Re02.g02000 C6 transcription factor 2651 12901 23151
Re02.g02010 Putative uncharacterized protein 2652 12902 23152
Re02.g02020 Putative uncharacterized protein 2653 12903 23153
Re02.g02030 Uncharacterized protein 2654 12904 23154
Re02.g02040 Putative uncharacterized protein 2655 12905 23155
Re02.g02050 Putative uncharacterized protein 2656 12906 23156
Re02.g02060 Putative uncharacterized protein 2657 12907 23157
Re02.g02070 hypothetical protein 2658 12908 23158
Re02.g02080 hypothetical protein 2659 12909 23159
Gag/polymerase/env polyprotein,
Re02.g02090 putative 2660 12910 23160
Re02.g02100 hypothetical protein 2661 1291 1 23161
Vegetative incompatibility protein
Re02.g021 10 HET-E-1 2662 12912 23162 31 132 32622
Re02.g02120 hypothetical protein 2663 12913 23163
Re02.g02130 Putative uncharacterized protein 2664 12914 23164
Similarity to hypothetical protein
Re02.g02140 encoded by slr0318 2665 12915 23165
Re02.g02150 Predicted protein 2666 12916 23166
Re02.g02160 Ankyrin repeat-containing protein 2667 12917 23167
Re02.g02170 Putative uncharacterized protein 2668 12918 23168
Re02.g02180 Putative uncharacterized protein 2669 12919 23169
Re02.g02190 Nuclear distribution protein PAC1 -1 2670 12920 23170
Para-aminobenzoate synthase
Re02.g02200 PabaA 2671 12921 23171
Re02.g02210 Uncharacterized protein 2672 12922 23172
Re02.g02220 Hypercellular protein HypA 2673 12923 23173
Re02.g02230 Uncharacterized protein 2674 12924 23174
Re02.g02240 DEAH-box RNA helicase 2675 12925 23175
Re02.g02250 RNA binding protein, putative 2676 12926 23176
mRNA binding protein Pumilio 2,
Re02.g02260 putative 2677 12927 23177
Re02.g02270 Uncharacterized protein 2678 12928 23178
Re02.g02280 Uncharacterized protein 2679 12929 23179
Re02.g02290 GTPase activating protein 2680 12930 23180
Re02.g02300 Importin-alpha re-exporter 2681 12931 23181
Re02.g02310 Uncharacterized protein Fragment 2682 12932 23182
Re02.g02320 Putative uncharacterized protein 2683 12933 23183
Re02.g02330 Putative uncharacterized protein 2684 12934 23184
Re02.g02340 Uncharacterized protein 2685 12935 23185
Re02.g02350 Cell cycle control protein Cdc123 2686 12936 23186
Re02.g02360 Uncharacterized protein 2687 12937 23187
Re02.g02370 Uncharacterized protein Fragment 2688 12938 23188
Re02.g02380 HEAT repeat protein 2689 12939 23189 Re02.g02390 DUF28 domain protein 2690 12940 23190
Re02.g02400 Mis6 domain protein 2691 12941 23191
Re02.g02410 Transmembrane protein 2692 12942 23192
Short-chain dehydrogenase,
Re02.g02420 putative 2693 12943 23193
Re02.g02430 Putative uncharacterized protein 2694 12944 23194
Putative uncharacterized protein
Re02.g02440 An15g01380 2695 12945 23195
Killer toxin sensitivity protein (Iki1 ),
Re02.g02450 putative 2696 12946 23196
Re02.g02460 Glycosyl transferase, putative 2697 12947 23197 31 133 32623
Re02.g02470 Glycosyl transferase, putative 2698 12948 23198 31 134 32624
Glycan biosynthesis protein (PigL),
Re02.g02480 putative 2699 12949 23199
Re02.g02490 Putative uncharacterized protein 2700 12950 23200
FAD dependent oxidoreductase,
Re02.g02500 putative 2701 12951 23201
Mannosyl-oligosaccharide
Re02.g02510 glucosidase, putative 2702 12952 23202 31 135 32625
Re02.g02520 Putative uncharacterized protein 2703 12953 23203
Re02.g02530 Uncharacterized protein 2704 12954 23204
Re02.g02540 RING finger protein 2705 12955 23205
Re02.g02550 PAP2 domain protein 2706 12956 23206
Transmembrane hyphal
Re02.g02560 anastomosis protein Ham2/Far1 1 2707 12957 23207
Re02.g02570 Uncharacterized protein 2708 12958 23208 31 136 32626
Ribosomal large subunit
Re02.g02580 biogenesis protein MAK16 2709 12959 23209
tRNA splicing 2'
Re02.g02590 phosphotransferase 1 2710 12960 23210
Re02.g02600 Uncharacterized protein 271 1 12961 2321 1 31 137 32627
Re02.g02610 Uncharacterized protein 2712 12962 23212
Re02.g02620 Uncharacterized protein 2713 12963 23213
Re02.g02630 MFS sugar transporter, putative 2714 12964 23214
Phospholipid-translocating P-type
Re02.g02640 ATPase, putative 2715 12965 23215
COPII vesicle coat protein Sec16,
Re02.g02650 putative 2716 12966 23216
Re02.g02660 Cell cycle checkpoint protein 2717 12967 23217
Re02.g02670 Hexokinase, putative 2718 12968 23218
Re02.g02680 GAS2 domain protein 2719 12969 23219
GTPase activating protein (Gyp7),
Re02.g02690 putative 2720 12970 23220
Re02.g02700 Alpha/beta hydrolase fold protein 2721 12971 23221
Re02.g02710 Uncharacterized protein Fragment 2722 12972 23222
Integral membrane protein,
Re02.g02720 Mpv17/PMP22 family, putative 2723 12973 23223 31 138 32628
Re02.g02730 hypothetical protein 2724 12974 23224
Re02.g02740 F-box domain protein 2725 12975 23225 Re02.g02750 Catalase EC=1.1 1.1.6 2726 12976 23226
Re02.g02760 Tetratricopeptide repeat protein 2727 12977 23227
Re02.g02770 MFS transporter, putative 2728 12978 23228
Re02.g02780 Putative uncharacterized protein 2729 12979 23229
Putative uncharacterized protein
Re02.g02790 An18g01010 2730 12980 23230
Re02.g02800 GNAT family acetyltransferase 2731 12981 23231
Re02.g02810 Uncharacterized protein 2732 12982 23232
Re02.g02820 ER to Golgi transport protein Yi l 2733 12983 23233
Re02.g02830 Ribosomal protein L14 2734 12984 23234
Nascent polypeptide-associated
Re02.g02840 complex (NAC) subunit, putative 2735 12985 23235
ATP synthase D chain,
Re02.g02850 mitochondrial, putative 2736 12986 23236
Re02.g02860 Reverse transcriptase, putative 2737 12987 23237
Re02.g02870 Uncharacterized protein 2738 12988 23238
Re02.g02880 Putative uncharacterized protein 2739 12989 23239
Re02.g02890 Oxidoreductase (Msc7), putative 2740 12990 23240
Similarity to the
apurinic/apyrimidinic endonuclease
Re02.g02900 III family Precursor 2741 12991 23241
Re02.g02910 Amidophosphoribosyltransferase 2742 12992 23242 31 139 32629
C-5 cytosine methyltransferase
Re02.g02920 DmtA 2743 12993 23243
2-methylcitrate dehydratase,
Re02.g02930 putative 2744 12994 23244 31 140 32630
Re02.g02940 hypothetical protein 2745 12995 23245 31 141 32631
Re02.g02950 Uncharacterized protein 2746 12996 23246 31 142 32632
Re02.g02960 8-amino-7-oxononanoate synthase 2747 12997 23247
Onanonoxo-7-onima-8-
Re02.g02970 eninoihtemlysoneda 2748 12998 23248
Re02.g02980 Biotin synthase EC=2.8.1.6 2749 12999 23249
Re02.g02990 Uncharacterized protein 2750 13000 23250
Integral membrane protein (Pth1 1 ),
Re02.g03000 putative 2751 13001 23251
Benzoate 4-monooxygenase
Re02.g03010 cytochrome P450, putative 2752 13002 23252 31 143 32633
Re02.g03020 Pc20g13500 protein Precursor 2753 13003 23253 31 144 32634
Re02.g03030 Citrate synthase 2754 13004 23254
Re02.g03040 Isocitrate lyase Precursor 2755 13005 23255 31 145 32635 mRNA-nucleus export ATPase
Re02.g03050 (Elf1 ), putative 2756 13006 23256
Re02.g03060 Putative uncharacterized protein 2757 13007 23257
Re02.g03070 Urease accessory protein UreD 2758 13008 23258
High-affinity nickel transport protein
Re02.g03080 nid , putative 2759 13009 23259 31 146 32636
Re02.g03090 Putative uncharacterized protein 2760 13010 23260 31 147 32637
Re02.g03100 Pc22g25260 protein 2761 1301 1 23261 31 148 32638
Re02.g031 10 hypothetical protein 2762 13012 23262 31 149 32639 Re02.g03120 Choline transport protein, putative 2763 13013 23263
Re02.g03130 Uncharacterized protein 2764 13014 23264
Re02.g03140 hypothetical protein 2765 13015 23265
Re02.g03150 hypothetical protein 2766 13016 23266 31 150 32640
Re02.g03160 Putative uncharacterized protein 2767 13017 23267
Glutathione-dependent
Re02.g03170 formaldehyde-activating, GFA 2768 13018 23268
Re02.g03180 hypothetical protein 2769 13019 23269
Re02.g03190 IgE-binding protein 2770 13020 23270 31 151 32641
Beta-glucosidase, putative
Re02.g03200 EC=3.2.1.21 2771 13021 23271
Re02.g03210 Acetamidase, putative 2772 13022 23272
Re02.g03220 Putative glutamine synthetase 2773 13023 23273
Short-chain
dehydrogenase/reductase family
Re02.g03230 protein 2774 13024 23274
5',5"'-P-1 ,Ρ-4-tetraphosphate
Re02.g03240 phosphorylase, putative 2775 13025 23275
Re02.g03250 hypothetical protein 2776 13026 23276
Re02.g03260 Putative uncharacterized protein 2777 13027 23277
Rad21/Rec8 N terminal domain
Re02.g03270 protein 2778 13028 23278 31 152 32642
Re02.g03280 hypothetical protein 2779 13029 23279
Re02.g03290 Acetylglutamate kinase, putative 2780 13030 23280
Re02.g03300 Pc22g23260 protein 2781 13031 23281
Glycosyl hydrolase family 76
Re02.g03310 protein 2782 13032 23282 31 153 32643
Re02.g03320 Protein disulfide-isomerase 2783 13033 23283 31 154 32644
Re02.g03330 Uncharacterized protein 2784 13034 23284 31 155 32645
Re02.g03340 Assembly factor cbp4 2785 13035 23285
Re02.g03350 Putative uncharacterized protein 2786 13036 23286
Re02.g03360 hypothetical protein 2787 13037 23287
Re02.g03370 hypothetical protein 2788 13038 23288
Remark: sequencing error at
Re02.g03380 position 15524 2789 13039 23289
NADH-ubiquinone oxidoreductase
Re02.g03390 105 kDa subunit 2790 13040 23290
Re02.g03400 UPF0041 domain protein 2791 13041 23291
Re02.g03410 hypothetical protein 2792 13042 23292 31 156 32646
Re02.g03420 Uncharacterized protein 2793 13043 23293 31 157 32647
Re02.g03430 Predicted protein 2794 13044 23294
Re02.g03440 Putative uncharacterized protein 2795 13045 23295
Re02.g03450 FAD binding domain protein 2796 13046 23296
Re02.g03460 Predicted protein 2797 13047 23297
Re02.g03470 Pc22g22790 protein 2798 13048 23298
C2H2 finger domain protein
Re02.g03480 (Zms1 ), putative 2799 13049 23299
Short chain
Re02.g03490 dehydrogenase/reductase, putative 2800 13050 23300 Re02.g03500 Uncharacterized protein 2801 13051 23301
Exopolygalacturonase X-1
Re02.g03510 EC=3.2.1.67 Precursor 2802 13052 23302 31 158 32648
Re02.g03520 hypothetical protein 2803 13053 23303 31 159 32649
Re02.g03530 hypothetical protein 2804 13054 23304 31 160 32650
Re02.g03540 hypothetical protein 2805 13055 23305
C2H2 finger domain protein,
Re02.g03550 putative 2806 13056 23306
Ankyrin repeat and BTB/POZ
Re02.g03560 domain protein 2807 13057 23307
G2-specific protein kinase NimA,
Re02.g03570 putative 2808 13058 23308
Re02.g03580 Putative uncharacterized protein 2809 13059 23309
Re02.g03590 Uncharacterized protein 2810 13060 23310
Putative uncharacterized protein
Re02.g03600 An12g08040 281 1 13061 2331 1
ATP dependent RNA helicase
Re02.g03610 (Sub2), putative 2812 13062 23312
Re02.g03620 hypothetical protein 2813 13063 23313
2-dehydropantoate 2-reductase,
Re02.g03630 putative 2814 13064 23314 31 161 32651
Re02.g03640 Putative uncharacterized protein 2815 13065 23315
Phosphoglycerate mutase family
Re02.g03650 protein 2816 13066 23316
Re02.g03660 Putative uncharacterized protein 2817 13067 23317
Re02.g03670 Putative uncharacterized protein 2818 13068 23318
Re02.g03680 Putative uncharacterized protein 2819 13069 23319
tRNA (Uracil-0(2)-)-
Re02.g03690 methyltransferase 2820 13070 23320
Re02.g03700 Putative uncharacterized protein 2821 13071 23321
Re02.g03710 Uncharacterized protein 2822 13072 23322 31 162 32652
Re02.g03720 Uncharacterized protein 2823 13073 23323
Re02.g03730 Putative uncharacterized protein 2824 13074 23324 31 163 32653
Re02.g03740 Lipase, putative 2825 13075 23325
Re02.g03750 Oxidoreductase 2826 13076 23326
Multiple inositol polyphosphate
Re02.g03760 phosphatase 2827 13077 23327 31 164 32654
Re02.g03770 Uncharacterized protein 2828 13078 23328
Nascent polypeptide-associated
Re02.g03780 complex subunit beta 2829 13079 23329
Re02.g03790 Uncharacterized protein 2830 13080 23330
Putative uncharacterized protein
Re02.g03800 An12g07760 EC=3.1.1.5 2831 13081 23331
Re02.g03810 Uncharacterized protein 2832 13082 23332 31 165 32655
Re02.g03820 Ctr copper transporter, putative 2833 13083 23333
Re02.g03830 Metalloreductase, putative 2834 13084 23334
Sterol delta 5,6-desaturase,
Re02.g03840 putative 2835 13085 23335
Re02.g03850 Putative uncharacterized protein 2836 13086 23336 Serine/threonine protein kinase,
Re02.g03860 putative 2837 13087 23337
Ethanolamine utilization protein
Re02.g03870 (EutQ), putative 2838 13088 23338
Re02.g03880 C6 finger domain protein, putative 2839 13089 23339
Glutamate decarboxylase, putative
Re02.g03890 EC=4.1.1.15 2840 13090 23340
Gag/polymerase/env polyprotein,
Re02.g03900 putative 2841 13091 23341
Re02.g03910 hypothetical protein 2842 13092 23342
C2H2 finger domain protein,
Re02.g03920 putative 2843 13093 23343
NAD binding Rossmann fold
Re02.g03930 oxidoreductase, putative 2844 13094 23344
Re02.g03940 Uncharacterized protein 2845 13095 23345
Re02.g03950 Putative uncharacterized protein 2846 13096 23346
Re02.g03960 Putative uncharacterized protein 2847 13097 23347
Re02.g03970 Pc22g24530 protein 2848 13098 23348
Re02.g03980 C6 finger domain protein 2849 13099 23349
Re02.g03990 Putative uncharacterized protein 2850 13100 23350
Re02.g04000 Haemolysin-lll related protein 2851 13101 23351
Re02.g04010 hypothetical protein 2852 13102 23352
GATA transcriptional activator
Re02.g04020 AreA 2853 13103 23353
Re02.g04030 Glutathione S-transferase, putative 2854 13104 23354
Re02.g04040 Aminotransferase 2855 13105 23355
rRNA processing protein Ipi1 ,
Re02.g04050 putative 2856 13106 23356
Similar to FAD binding domain
Re02.g04060 containing protein 2857 13107 23357 31166 32656
Re02.g04070 NCS1 allantoate transporter 2858 13108 23358
Re02.g04080 Putative uncharacterized protein 2859 13109 23359 31167 32657
Re02.g04090 Similar to An12g02300 2860 13110 23360
Re02.g04100 G1/S-specific cyclin Pcl5, putative 2861 13111 23361
RNA polymerase II transcription
mediator complex subunit (Med6),
Re02.g04110 putative 2862 13112 23362
Re02.g04120 RNA-dependent RNA polymerase 2863 13113 23363
Re02.g04130 hypothetical protein 2864 13114 23364 31168 32658
Re02.g04140 Lysine decarboxylase-like protein 2865 13115 23365
Proteasome subunit alpha type
Re02.g04150 EC=3.4.25.1 2866 13116 23366
Vacuolar protein sorting 55
Re02.g04160 superfamily 2867 13117 23367
Re02.g04170 Putative uncharacterized protein 2868 13118 23368
Re02.g04180 UPF0220 domain protein 2869 13119 23369
Hsp70 nucleotide exchange factor
Re02.g04190 (Fes1), putative 2870 13120 23370
Re02.g04200 Actin, gamma 2871 13121 23371 Bifunctional purine biosynthetic
Re02.g04210 protein Ade1 , putative 2872 13122 23372
Mitochondrial mRNA processing
Re02.g04220 protein PET127, putative 2873 13123 23373
Re02.g04230 Putative uncharacterized protein 2874 13124 23374 31 169 32659
Re02.g04240 Putative uncharacterized protein 2875 13125 23375
Imidazoleglycerol-phosphate
Re02.g04250 dehydratase 2876 13126 23376
Re02.g04260 Uncharacterized protein 2877 13127 23377
Re02.g04270 Uncharacterized protein 2878 13128 23378
Putative alpha-1 ,6-
Re02.g04280 mannosyltransferase 2879 13129 23379 31 170 32660
ER-associated proteolytic system
Re02.g04290 protein Deri 2880 13130 23380
Re02.g04300 Histone 3-like protein 2881 13131 23381
Re02.g04310 Similarity to other proteins 2882 13132 23382
Re02.g04320 Putative uncharacterized protein 2883 13133 23383
Re02.g04330 Putative uncharacterized protein 2884 13134 23384
Similarity to 14.8 kD subunit of
Re02.g04340 NADH:ubiquinone reductase 2885 13135 23385
DNA-directed RNA polymerase I
Re02.g04350 and III 14 kDa polypeptide 2886 13136 23386
Re02.g04360 hypothetical protein 2887 13137 23387
Re02.g04370 MFS monocarboxylate transporter 2888 13138 23388
Homeobox and C2H2 transcription
Re02.g04380 factor, putative 2889 13139 23389
Re02.g04390 Threonine dehydratase 2890 13140 23390
Re02.g04400 Putative uncharacterized protein 2891 13141 23391
Translation factor gufl ,
Re02.g04410 mitochondrial EC=3.6.5.- Precursor 2892 13142 23392
Mitotic spindle checkpoint
Re02.g04420 component mad2 2893 13143 23393
Re02.g04430 Uncharacterized protein Fragment 2894 13144 23394
Re02.g04440 Putative uncharacterized protein 2895 13145 23395
Golgi transport protein Sly1 ,
Re02.g04450 putative 2896 13146 23396
Re02.g04460 FHA domain protein 2897 13147 23397
Putative uncharacterized protein
Re02.g04470 An03g04790 2898 13148 23398
Re02.g04480 Uncharacterized protein 2899 13149 23399
Re02.g04490 MSF1 domain protein 2900 13150 23400
Re02.g04500 Uncharacterized protein 2901 13151 23401 31 171 32661
Re02.g04510 hypothetical protein 2902 13152 23402 31 172 32662
Serine/threonine protein kinase
Re02.g04520 (Sn l p), putative 2903 13153 23403
Re02.g04530 Putative uncharacterized protein 2904 13154 23404
Re02.g04540 Uncharacterized protein 2905 13155 23405
Miscellaneous Zn(ll)2Cys6
Re02.g04550 transcription factor 2906 13156 23406 Re02.g04560 Uncharacterized protein 2907 13157 23407 31 173 32663
Re02.g04570 Cell wall glucanase, putative 2908 13158 23408 31 174 32664
Re02.g04580 Lipase/thioesterase family protein 2909 13159 23409
Flavin-binding monooxygenase,
Re02.g04590 putative 2910 13160 23410
Re02.g04600 Putative uncharacterized protein 291 1 13161 2341 1
Re02.g04610 Sugar transporter, putative 2912 13162 23412
Re02.g04620 Putative uncharacterized protein 2913 13163 23413
Re02.g04630 Putative uncharacterized protein 2914 13164 23414
Re02.g04640 PLC-A 2915 13165 23415 31 175 32665
2,4-dichlorophenol 6-
Re02.g04650 monooxygenase EC=1.14.13.20 2916 13166 23416
Re02.g04660 Putative uncharacterized protein 2917 13167 23417
Alpha-glucosidase/alpha-amylase,
Re02.g04670 putative 2918 13168 23418
Re02.g04680 Alpha-amylase 2919 13169 23419
Re02.g04690 hypothetical protein 2920 13170 23420 31 176 32666
Re02.g04700 Uncharacterized protein 2921 13171 23421
Re02.g04710 Rad4 family protein 2922 13172 23422
Re02.g04720 HIT domain protein 2923 13173 23423 31 177 32667
Re02.g04730 Uncharacterized protein 2924 13174 23424
Re02.g04740 Putative uncharacterized protein 2925 13175 23425
Re02.g04750 CobW domain protein 2926 13176 23426
Re02.g04760 Mob1 family protein 2927 13177 23427
Re02.g04770 hypothetical protein 2928 13178 23428
Protein kinase domain-containing
Re02.g04780 protein 2929 13179 23429
Re02.g04790 Signal transduction protein BroA 2930 13180 23430
Mitochondrial DnaJ chaperone
Re02.g04800 (Mdj1 ), putative 2931 13181 23431 31 178 32668
Lon protease homolog,
Re02.g04810 mitochondrial EC=3.4.21.- 2932 13182 23432
2-dehydropantoate 2-reductase
Re02.g04820 EC=1.1.1.169 2933 13183 23433
Re02.g04830 Uncharacterized protein 2934 13184 23434
Re02.g04840 Uncharacterized protein 2935 13185 23435
Re02.g04850 Catabolite repressor CreT 2936 13186 23436
Re02.g04860 Uncharacterized protein 2937 13187 23437
Re02.g04870 Putative uncharacterized protein 2938 13188 23438 31 179 32669
Re02.g04880 Putative uncharacterized protein 2939 13189 23439
Re02.g04890 Putative uncharacterized protein 2940 13190 23440
Re02.g04900 Putative uncharacterized protein 2941 13191 23441
Podospora anserina S mat+
genomic DNA chromosome 6,
Re02.g04910 supercontig 4 2942 13192 23442
Re02.g04920 Purine permease, putative 2943 13193 23443
Stearic acid desaturase (SdeA),
Re02.g04930 putative 2944 13194 23444
Re02.g04940 Metallopeptidase MepB 2945 13195 23445 EC=3.4.24.37
Re02.g04950 Uncharacterized protein 2946 13196 23446
Re02.g04960 Predicted protein 2947 13197 23447
Re02.g04970 Uncharacterized protein Fragment 2948 13198 23448 31 180 32670
C2H2 finger domain protein,
Re02.g04980 putative 2949 13199 23449
mRNA transport regulator (Mtr10),
Re02.g04990 putative 2950 13200 23450 31 181 32671
Small nuclear ribonucleoprotein
Re02.g05000 SmE, putative 2951 13201 23451
5-formyltetrahydrofolate cyclo-
Re02.g05010 ligase, putative 2952 13202 23452
Re02.g05020 Uncharacterized protein 2953 13203 23453 31 182 32672
Re02.g05030 Uncharacterized protein 2954 13204 23454
Re02.g05040 Non-repetitive nudeoporin, putative 2955 13205 23455
Re02.g05050 WD domain protein 2956 13206 23456
Sterigmatocystin 8-0-
Re02.g05060 methyltransferase, putative 2957 13207 23457
Re02.g05070 Predicted protein 2958 13208 23458
Re02.g05080 Nucleolar GTP-binding protein 1 2959 13209 23459
GNAT family acetyltransferase,
Re02.g05090 putative 2960 13210 23460
Re02.g05100 hypothetical protein 2961 1321 1 23461
DNA damage-inducible v-SNARE
Re02.g051 10 binding protein Ddi1 , putative 2962 13212 23462
Re02.g05120 Integral membrane protein 2963 13213 23463 31 183 32673
Re02.g05130 hypothetical protein 2964 13214 23464
Re02.g05140 Uncharacterized protein 2965 13215 23465 31 184 32674
Re02.g05150 hypothetical protein 2966 13216 23466 31 185 32675
Re02.g05160 Uncharacterized protein 2967 13217 23467 31 186 32676
Re02.g05170 hypothetical protein 2968 13218 23468
Re02.g05180 hypothetical protein 2969 13219 23469
Re02.g05190 Choline dehydrogenase, putative 2970 13220 23470 31 187 32677
MFS monosaccharide transporter,
Re02.g05200 putative 2971 13221 23471
Re02.g05210 hypothetical protein 2972 13222 23472
Re02.g05220 3-ketoacyl-CoA reductase 2973 13223 23473
Re02.g05230 Ergosterol biosynthetic protein 28 2974 13224 23474 31 188 32678
Re02.g05240 hypothetical protein 2975 13225 23475
Galactose-1 -phosphate
Re02.g05250 uridylyltransferase EC=2.7.7.12 2976 13226 23476
Re02.g05260 Putative uncharacterized protein 2977 13227 23477
Re02.g05270 Acetylglutamate synthase 2978 13228 23478 31 189 32679
Re02.g05280 Uncharacterized protein 2979 13229 23479
Re02.g05290 Putative uncharacterized protein 2980 13230 23480 31 190 32680
Re02.g05300 Putative uncharacterized protein 2981 13231 23481
Mandelate racemase muconate
Re02.g05310 lactonizing protein 2982 13232 23482
Re02.g05320 Putative uncharacterized protein 2983 13233 23483
Figure imgf000089_0001
Re02.g05700 Uncharacterized protein 3021 13271 23521
3-oxoacyl-[acyl-carrier-protein]
Re02.g05710 reductase FabG 3022 13272 23522
Re02.g05720 Pc13g03500 protein 3023 13273 23523
Re02.g05730 Uncharacterized protein Fragment 3024 13274 23524
Re02.g05740 hypothetical protein 3025 13275 23525
Alpha- 1 ,3-glucan synthase Ags2
Re02.g05750 EC=2.4.1.183 3026 13276 23526 31 196 32686
Re02.g05760 Alpha- 1 ,3-glucan synthase Ags2 3027 13277 23527
Re02.g05770 Orotate phosphoribosyltransferase 3028 13278 23528
Methylenetetrahydrofolate
Re02.g05780 reductase 2 3029 13279 23529
Re02.g05790 Putative uncharacterized protein 3030 13280 23530
3-isopropylmalate dehydratase
Re02.g05800 EC=4.2.1.33 3031 13281 23531
Re02.g05810 Dihydroorotase, homodimeric type 3032 13282 23532
Re02.g05820 Uncharacterized protein 3033 13283 23533
Xenobiotic compound
Re02.g05830 monooxygenase, DszA family 3034 13284 23534
Re02.g05840 hypothetical protein 3035 13285 23535
Re02.g05850 Polyketide synthase, putative 3036 13286 23536
O-methyltransferase, putative
Re02.g05860 (AFU.orthologue AFUA_4G14580) 3037 13287 23537
Re02.g05870 O-methyltransferase family 2 3038 13288 23538 31 197 32687
Re02.g05880 Uncharacterized protein 3039 13289 23539
Re02.g05890 Putative mfs multidrug protein 3040 13290 23540
Oxidoreductase, short-chain
dehydrogenase/reductase family,
putative (AFU orthologue
Re02.g05900 AFUA_5G01040) 3041 13291 23541 31 198 32688
Podospora anserina S mat+
genomic DNA chromosome 5,
Re02.g05910 supercontig 10 3042 13292 23542
Cytochrome P450, putative
Re02.g05920 (Eurofung) 3043 13293 23543
Re02.g05930 hypothetical protein 3044 13294 23544
Oxidoreductase, zinc-binding
Re02.g05940 dehydrogenase family 3045 13295 23545
Re02.g05950 Uncharacterized protein 3046 13296 23546
Re02.g05960 DUF895 domain membrane protein 3047 13297 23547
Re02.g05970 hypothetical protein 3048 13298 23548
Re02.g05980 hypothetical protein 3049 13299 23549
Re02.g05990 Putative uncharacterized protein 3050 13300 23550
Re02.g06000 Methionine permease, putative 3051 13301 23551
Xenobiotic compound
Re02.g06010 monooxygenase, DszA family 3052 13302 23552
UDP-N-acetyl-glucosamine-1-P
transferase Alg7, putative
Re02.g06020 EC=2.7.8.15 3053 13303 23553
Re02.g06030 Nuclear pore protein 3054 13304 23554 Re02.g06040 hypothetical protein 3055 13305 23555
Re02.g06050 Uncharacterized protein 3056 13306 23556
RNA polymerase II assessory
Re02.g06060 factor Cdc73p 3057 13307 23557
Re02.g06070 Developmental regulator FlbA 3058 13308 23558
Origin recognition complex subunit
Re02.g06080 Orc4, putative 3059 13309 23559
Re02.g06090 Uncharacterized protein 3060 13310 23560
Secretory pathway gdp dissociation
Re02.g06100 inhibitor 3061 1331 1 23561
54S ribosomal protein L4,
Re02.g061 10 mitochondrial Precursor 3062 13312 23562
Re02.g06120 Putative transcriptional regulator 3063 13313 23563
Re02.g06130 Uncharacterized protein 3064 13314 23564
Re02.g06140 Protein AMFR 3065 13315 23565
DNA replication complex GINS
Re02.g06150 protein PSF2 3066 13316 23566
Glucosyltransferase (Die2),
Re02.g06160 putative 3067 13317 23567 31 199 32689
Re02.g06170 Putative uncharacterized protein 3068 13318 23568
Tyrosyl-DNA phosphodiesterase,
Re02.g06180 putative 3069 13319 23569
Re02.g06190 Uncharacterized protein 3070 13320 23570
Re02.g06200 U-box domain protein 3071 13321 23571
Ribose/galactose isomerase,
Re02.g06210 putative 3072 13322 23572
Re02.g06220 Triosephosphate isomerase 3073 13323 23573
Dihydroo rotate reductase PyrE,
Re02.g06230 putative 3074 13324 23574
Putative uncharacterized protein
Re02.g06240 Fragment 3075 13325 23575 31200 32690
Re02.g06250 NAD-binding protein 3076 13326 23576
Re02.g06260 Uncharacterized protein 3077 13327 23577 31201 32691
Re02.g06270 Putative uncharacterized protein 3078 13328 23578
Re02.g06280 Putative uncharacterized protein 3079 13329 23579 31202 32692
C2H2 transcription factor (RfeC),
Re02.g06290 putative 3080 13330 23580
Re02.g06300 Uncharacterized protein 3081 13331 23581
Re02.g06310 Amino acid permease 3082 13332 23582
Re02.g06320 Disulfide isomerase, putative 3083 13333 23583 31203 32693
NADH-ubiquinone oxidoreductase
Re02.g06330 299 kDa subunit, putative 3084 13334 23584
Vesicle coat complex COPI, beta'
Re02.g06340 subunit 3085 13335 23585
Re02.g06350 Putative uncharacterized protein 3086 13336 23586 31204 32694
Re02.g06360 Uncharacterized protein 3087 13337 23587
Re02.g06370 Putative uncharacterized protein 3088 13338 23588
SAGA complex subunit (Ada2),
Re02.g06380 putative 3089 13339 23589 Serine/threonine protein kinase
Re02.g06390 (YPK1), putative 3090 13340 23590
Re02.g06400 hypothetical protein 3091 13341 23591
NADP(+)-dependent
Re02.g06410 dehydrogenase, putative 3092 13342 23592 31205 32695
Re02.g06420 hypothetical protein 3093 13343 23593
Re02.g06430 hypothetical protein 3094 13344 23594 31206 32696
MFS phosphate transporter,
Re02.g06440 putative 3095 13345 23595
Alpha-tubulin suppressor protein
Re02.g06450 Aatsl , putative 3096 13346 23596
Re02.g06460 Uncharacterized protein 3097 13347 23597
Re02.g06470 Uncharacterized protein 3098 13348 23598
Re02.g06480 DNA polymerase EC=2.7.7.7 3099 13349 23599
Re02.g06490 Pc22g21020 protein 3100 13350 23600
Re02.g06500 RNA helicase (Dbp), putative 3101 13351 23601
Re02.g06510 hypothetical protein 3102 13352 23602
C2H2 transcription factor (Con7),
Re02.g06520 putative 3103 13353 23603
Re02.g06530 Pentatricopeptide repeat protein 3104 13354 23604
Re02.g06540 Uncharacterized protein 3105 13355 23605
Nuclear protein export protein
Re02.g06550 Yrb2, putative 3106 13356 23606
Re02.g06560 DEAD/DEAH box helicase, putative 3107 13357 23607
Re02.g06570 Putative uncharacterized protein 3108 13358 23608
Re02.g06580 C6 finger domain protein, putative 3109 13359 23609
Re02.g06590 hypothetical protein 31 10 13360 23610
Phosphoribosylglycinamide
Re02.g06600 formyltransferase 31 1 1 13361 2361 1
Re02.g06610 RING finger protein 31 12 13362 23612
Re02.g06620 Uncharacterized protein 31 13 13363 23613 31207 32697
Re02.g06630 Uncharacterized protein 31 14 13364 23614
Re02.g06640 VPS9 domain protein 31 15 13365 23615
Re02.g06650 Putative lipase atg15 EC=3.1.1.3 31 16 13366 23616 31208 32698
Re02.g06660 Putative uncharacterized protein 31 17 13367 23617 31209 32699
Re02.g06670 Catalase isozyme P 31 18 13368 23618
Enoyl-CoA hydratase/isomerase
Re02.g06680 family protein 31 19 13369 23619
Re02.g06690 Protein rerl 3120 13370 23620
Re02.g06700 Putative uncharacterized protein 3121 13371 23621
ADP ribosylation factor A
Re02.g06710 (Eurofung) 3122 13372 23622
Chromatin remodeling complex
Re02.g06720 subunit 3123 13373 23623
Re02.g06730 Putative uncharacterized protein 3124 13374 23624
Re02.g06740 Cellobiose dehydrogenase 3125 13375 23625 31210 32700
Re02.g06750 Prephenate dehydrogenase 3126 13376 23626
Re02.g06760 40S ribosomal protein S1 1 3127 13377 23627
Re02.g06770 Uncharacterized protein 3128 13378 23628 Re02.g06780 40S ribosomal protein S9 3129 13379 23629
Re02.g06790 50S ribosomal protein L13 3130 13380 23630
Re02.g06800 Uricase EC=1.7.3.3 3131 13381 23631
Cytosolic regulator Pianissimo,
Re02.g06810 putative 3132 13382 23632
Re02.g06820 ATP-dependent protease 3133 13383 23633
Re02.g06830 Uncharacterized protein 3134 13384 23634
Re02.g06840 Predicted protein 3135 13385 23635
Re02.g06850 Predicted protein 3136 13386 23636
Eukaryotic translation initiation
Re02.g06860 factor 3 subunit L 3137 13387 23637
Iron-sulfur cluster assembly
Re02.g06870 accessory protein Isa2, putative 3138 13388 23638
Re02.g06880 Kynureninase 3139 13389 23639
Re02.g06890 Uncharacterized protein 3140 13390 23640
Putative uncharacterized protein
Re02.g06900 An16g04640 3141 13391 23641
AP-2 adaptor complex subunit
Re02.g06910 beta, putative 3142 13392 23642
Re02.g06920 SH3 domain protein 3143 13393 23643
Re02.g06930 DUF408 domain protein 3144 13394 23644
Re02.g06940 40S ribosomal protein S17 3145 13395 23645
Re02.g06950 Uncharacterized protein 3146 13396 23646 3121 1 32701
Re02.g06960 Pc22g20490 protein 3147 13397 23647
TOR pathway phosphatidylinositol
Re02.g06970 3-kinase TorA 3148 13398 23648
Re02.g06980 Putative uncharacterized protein 3149 13399 23649
NAD binding Rossmann fold
Re02.g06990 oxidoreductase, putative 3150 13400 23650
UDP-glucoronosyl and UDP-
Re02.g07000 glucosyl transferase family protein 3151 13401 23651 31212 32702
Re02.g07010 Glycerol dehydrogenase, putative 3152 13402 23652
Localization: the C.
gloeosporioides homolog alr6 is a
Re02.g07020 putative peroxisomal protein 3153 13403 23653
Re02.g07030 Siderophore iron transporter 3154 13404 23654
Re02.g07040 Uncharacterized protein Fragment 3155 13405 23655
Re02.g07050 hypothetical protein 3156 13406 23656
Re02.g07060 Putative uncharacterized protein 3157 13407 23657
Re02.g07070 hypothetical protein 3158 13408 23658
Re02.g07080 Putative uncharacterized protein 3159 13409 23659 31213 32703
Integral peroxisomal membrane
Re02.g07090 protein 3160 13410 23660
Re02.g07100 Putative integral membrane protein 3161 1341 1 23661
Re02.g071 10 Putative uncharacterized protein 3162 13412 23662
Re02.g07120 Cochaperone Pam16 3163 13413 23663
L-galactose dehydrogenase (L-
Re02.g07130 GalDH), putative 3164 13414 23664
Re02.g07140 Pantothenate transporter, putative 3165 13415 23665 Topoisomerase family protein
TRF4, putative (AFU orthologue
Re02.g07150 AFUA_7G04130) 3166 13416 23666
Re02.g07160 DUF636 domain protein 3167 13417 23667 31214 32704
Re02.g07170 hypothetical protein 3168 13418 23668 31215 32705
Re02.g07180 hypothetical protein 3169 13419 23669
Protein kinase C substrate,
Re02.g07190 putative 3170 13420 23670 31216 32706
Re02.g07200 Putative uncharacterized protein 3171 13421 23671
Re02.g07210 Putative uncharacterized protein 3172 13422 23672
3-ketoacyl-CoA thiolase (POT1 ),
putative (AFU orthologue
Re02.g07220 AFUA_7G04080) 3173 13423 23673
Re02.g07230 Putative uncharacterized protein 3174 13424 23674
Phospho-2-dehydro-3- deoxyheptonate aldolase
Re02.g07240 EC=2.5.1.54 3175 13425 23675
Re02.g07250 Uncharacterized protein 3176 13426 23676
Re02.g07260 Uncharacterized protein 3177 13427 23677
Re02.g07270 Hexokinase-1 EC=2.7.1.1 3178 13428 23678
Re02.g07280 hypothetical protein 3179 13429 23679
Re02.g07290 Putative uncharacterized protein 3180 13430 23680
Re02.g07300 Lipase, putative 3181 13431 23681
Peroxisome biosynthesis protein
Re02.g07310 (PAS1/Peroxin-1 ), putative 3182 13432 23682
DNA replication licensing factor
Re02.g07320 Mcm7, putative 3183 13433 23683
Re02.g07330 Transposase 3184 13434 23684
Re02.g07340 Putative uncharacterized protein 3185 13435 23685 31217 32707
Re02.g07350 Putative uncharacterized protein 3186 13436 23686
Re02.g07360 Phenylacetyl-CoA ligase, putative 3187 13437 23687
Re02.g07370 hypothetical protein 3188 13438 23688
Cyclopropane-fatty-acyl-
Re02.g07380 phospholipid synthase, putative 3189 13439 23689
Re02.g07390 Uncharacterized protein 3190 13440 23690
Re02.g07400 Uncharacterized protein 3191 13441 23691
Re02.g07410 Putative uncharacterized protein 3192 13442 23692
Re02.g07420 Putative uncharacterized protein 3193 13443 23693 31218 32708
Re02.g07430 Putative uncharacterized protein 3194 13444 23694 31219 32709
Re02.g07440 hypothetical protein 3195 13445 23695
Similarity to CSI2 like protein
CAC28732.1 -Neurospora crassa
Re02.g07450 Precursor 3196 13446 23696
Protein-ER retention protein (Erd1 ),
Re02.g07460 putative 3197 13447 23697
Peroxisome biosynthesis protein
Re02.g07470 (Peroxin-10), putative 3198 13448 23698
Re02.g07480 Uncharacterized protein 3199 13449 23699
Re02.g07490 Small nuclear ribonucleoprotein 3200 13450 23700 (LSM5), putative
Amino acid permease (Gap1 ),
Re02.g07500 putative 3201 13451 23701
Re02.g07510 Uncharacterized protein 3202 13452 23702
Cell division control protein Cdc6,
Re02.g07520 putative 3203 13453 23703
Re02.g07530 Putative uncharacterized protein 3204 13454 23704
Re02.g07540 hypothetical protein 3205 13455 23705 31220 32710
Re02.g07550 Serine/threonine-protein kinase 3206 13456 23706
Re02.g07560 C6 transcription factor, putative 3207 13457 23707
Mandelate racemase/muconate
Re02.g07570 lactonizing enzyme family protein 3208 13458 23708
Re02.g07580 Alcohol dehydrogenase 3209 13459 23709 31221 3271 1
Re02.g07590 Putative uncharacterized protein 3210 13460 23710
Alcohol dehydrogenase 2
Re02.g07600 EC=1.1.1.1 321 1 13461 2371 1
Re02.g07610 Putative uncharacterized protein 3212 13462 23712
Re02.g07620 Putative uncharacterized protein 3213 13463 23713
Re02.g07630 SAP domain protein 3214 13464 23714
Re02.g07640 hypothetical protein 3215 13465 23715 31222 32712
Re02.g07650 C2H2 zinc finger protein 3216 13466 23716
Re02.g07660 Putative uncharacterized protein 3217 13467 23717
Re02.g07670 Putative uncharacterized protein 3218 13468 23718
Alpha.alpha-trehalose phosphate
Re02.g07680 synthase subunit TPS3, putative 3219 13469 23719 31223 32713
Re02.g07690 Putative uncharacterized protein 3220 13470 23720
Re02.g07700 Thioesterase family protein 3221 13471 23721
Re02.g07710 Putative uncharacterized protein 3222 13472 23722
Re02.g07720 Putative uncharacterized protein 3223 13473 23723 31224 32714
Eukaryotic translation initiation
Re02.g07730 factor 3 subunit M 3224 13474 23724
Re02.g07740 Uridylate kinase Ura6 3225 13475 23725
Re02.g07750 hypothetical protein 3226 13476 23726 31225 32715
Re02.g07760 Uncharacterized protein 3227 13477 23727
Re02.g07770 Uncharacterized protein 3228 13478 23728 31226 32716
Re02.g07780 Putative uncharacterized protein 3229 13479 23729
Re02.g07790 Condensin complex subunit 2 3230 13480 23730
Re02.g07800 Sodium/calcium exchanger protein 3231 13481 23731 31227 32717
Re02.g07810 Uncharacterized protein 3232 13482 23732
DNA-directed RNA polymerase II
Re02.g07820 subunit RPB1 1 a, putative 3233 13483 23733
Oxidoreductase, 2-nitropropane
Re02.g07830 dioxygenase family, putative 3234 13484 23734 31228 32718
Re02.g07840 Putative uncharacterized protein 3235 13485 23735
Re02.g07850 hypothetical protein 3236 13486 23736
Re02.g07860 DNA repair protein Rad7, protein 3237 13487 23737
DNA excision repair protein Rad16,
Re02.g07870 putative 3238 13488 23738
Re02.g07880 C2 domain protein 3239 13489 23739 ARF GTPase activator (Csx2),
Re02.g07890 putative 3240 13490 23740
Re02.g07900 Putative uncharacterized protein 3241 13491 23741
Re02.g07910 Uncharacterized protein 3242 13492 23742
Phosphatidylinositol 4-kinase
Re02.g07920 (STT4), putative 3243 13493 23743
Cell-cycle checkpoint protein
Re02.g07930 kinase, putative EC=2.7.1 1.17 3244 13494 23744
14-alpha sterol demethylase
Re02.g07940 Cyp51 B EC=1.14.13.70 3245 13495 23745
Re02.g07950 Putative uncharacterized protein 3246 13496 23746
Serine/threonine-protein kinase
Re02.g07960 KIN28 3247 13497 23747
Kinesin family protein (KipA),
Re02.g07970 putative 3248 13498 23748
Re02.g07980 Putative uncharacterized protein 3249 13499 23749
Re02.g07990 Uncharacterized protein 3250 13500 23750
Re02.g08000 Protein pxrl 3251 13501 23751
Re02.g08010 Uncharacterized protein 3252 13502 23752
Re02.g08020 Uncharacterized protein 3253 13503 23753
Re02.g08030 Putative uncharacterized protein 3254 13504 23754
AP-3 complex subunit delta,
Re02.g08040 putative 3255 13505 23755
Re02.g08050 Putative uncharacterized protein 3256 13506 23756
Re02.g08060 Putative uncharacterized protein 3257 13507 23757
Re02.g08070 Putative uncharacterized protein 3258 13508 23758
Putative uncharacterized protein
Re02.g08080 Fragment 3259 13509 23759
Re02.g08090 Putative uncharacterized protein 3260 13510 23760
Re02.g08100 Putative uncharacterized protein 3261 1351 1 23761
Histone-lysine N- methyltransferase, H3 lysine-4
Re02.g081 10 specific 3262 13512 23762
AdoMet-dependent tRNA
methyltransferase complex subunit,
Re02.g08120 putative 3263 13513 23763
Re02.g08130 Uncharacterized protein 3264 13514 23764
Re02.g08140 Uncharacterized protein 3265 13515 23765
Methylthioribose-1 -phosphate
Re02.g08150 isomerase EC=5.3.1.23 3266 13516 23766
Glucosamine~fructose-6-
Re02.g08160 phosphate aminotransferase 3267 13517 23767
6,7-dimethyl-8-ribityllumazine
Re02.g08170 synthase EC=2.5.1.78 3268 13518 23768
Proteasome subunit alpha type
Re02.g08180 EC=3.4.25.1 3269 13519 23769
Re02.g08190 Putative uncharacterized protein 3270 13520 23770
NAD(+)-isocitrate dehydrogenase
Re02.g08200 subunit I 3271 13521 23771
Re02.g08210 Uncharacterized protein 3272 13522 23772 Re02.g08220 Putative uncharacterized protein 3273 13523 23773 31229 32719
Rho GTPase activator (Bem3),
Re02.g08230 putative 3274 13524 23774 31230 32720
Re02.g08240 Uncharacterized protein 3275 13525 23775
rRNA processing protein (Rrp20),
Re02.g08250 putative 3276 13526 23776
Proteasome component Prs3,
Re02.g08260 putative 3277 13527 23777
Re02.g08270 Pc14g01240 protein 3278 13528 23778
Proteasome subunit beta type
Re02.g08280 EC=3.4.25.1 3279 13529 23779
Fumarylacetoacetate hydrolase
Re02.g08290 family protein 3280 13530 23780
Re02.g08300 30 kDa heat shock protein 3281 13531 23781
Re02.g08310 Putative uncharacterized protein 3282 13532 23782
Re02.g08320 Putative uncharacterized protein 3283 13533 23783
U1 small nuclear ribonucleoprotein
Re02.g08330 A 3284 13534 23784
Actin-related protein 2/3 complex
Re02.g08340 subunit 1 3285 13535 23785
Extracellular triacylglycerol lipase,
Re02.g08350 putative 3286 13536 23786 31231 32721
Re02.g08360 WW domain protein 3287 13537 23787
Re02.g08370 Putative uncharacterized protein 3288 13538 23788 31232 32722
Proteasome component (Ecm29),
Re02.g08380 putative 3289 13539 23789
SNF2 family helicase/ATPase,
Re02.g08390 putative 3290 13540 23790
Re02.g08400 Putative uncharacterized protein 3291 13541 23791 31233 32723
Putative Short-chain
dehydrogenase TIC 32,
Re02.g08410 chloroplastic 3292 13542 23792
Mitochondrial protein FMP32,
Re02.g08420 putative 3293 13543 23793
Re02.g08430 Phosphomannomutase 3294 13544 23794
Similar to G protein coupled
Re02.g08440 receptor family protein 3295 13545 23795
Re02.g08450 DnaJ chaperone (Caj1 ), putative 3296 13546 23796
Re02.g08460 Putative uncharacterized protein 3297 13547 23797
Re02.g08470 DnaJ domain protein 3298 13548 23798 31234 32724
COPII vesicles protein Yip3,
Re02.g08480 putative 3299 13549 23799
Re02.g08490 FK506 suppressor Sfk1 , putative 3300 13550 23800 31235 32725
20G-Fe(ll) oxygenase family
Re02.g08500 oxidoreductase, putative 3301 13551 23801
Re02.g08510 MFS multidrug transporter, putative 3302 13552 23802
Flavin-containing amine oxidase,
Re02.g08520 putative 3303 13553 23803
Re02.g08530 Uncharacterized protein 3304 13554 23804
Re02.g08540 Putative uncharacterized protein 3305 13555 23805 31236 32726 Re02.g08550 MFS transporter, putative 3306 13556 23806
Re02.g08560 Uncharacterized protein 3307 13557 23807 31237 32727
Re02.g08570 Uncharacterized protein 3308 13558 23808 31238 32728
Geranylgeranyl transferase beta
Re02.g08580 subunit, putative 3309 13559 23809
Serine/threonine protein kinase,
Re02.g08590 putative 3310 13560 23810
Re02.g08600 Uncharacterized protein 331 1 13561 2381 1
Endoplasmic reticulum calcium
Re02.g08610 ATPase, putative 3312 13562 23812
Re02.g08620 hypothetical protein 3313 13563 23813 31239 32729
Putative uncharacterized protein
Re02.g08630 An18g06270 3314 13564 23814
Eukaryotic translation initiation
Re02.g08640 factor 3 subunit J 3315 13565 23815
Re02.g08650 Enolase/allergen Asp F 22 3316 13566 23816
26S proteasome regulatory
Re02.g08660 complex, ATPase RPT4 3317 13567 23817
Mannosyl-oligosaccharide alpha-
Re02.g08670 1 ,2-mannosidase 3318 13568 23818
Re02.g08680 Peptidase, putative 3319 13569 23819 31240 32730
Sensor histidine kinase/response
Re02.g08690 regulator, putative 3320 13570 23820
Re02.g08700 Epoxide hydrolase 3321 13571 23821
Re02.g08710 60S ribosomal protein L36 3322 13572 23822
Re02.g08720 UBX domain protein, putative 3323 13573 23823
Proteasome subunit beta type
Re02.g08730 EC=3.4.25.1 3324 13574 23824
Re02.g08740 Putative uncharacterized protein 3325 13575 23825
Cytochrome c oxidase-assembly
factor cox23, mitochondrial,
Re02.g08750 putative 3326 13576 23826
Re02.g08760 Uncharacterized protein 3327 13577 23827
Re02.g08770 Predicted protein 3328 13578 23828
Re02.g08780 Putative uncharacterized protein 3329 13579 23829
Re02.g08790 rRNA processing protein RRP9 3330 13580 23830
Re02.g08800 Proteasome component C1 1 3331 13581 23831
Re02.g08810 SnRNP assembly factor, putative 3332 13582 23832
Re02.g08820 Uncharacterized protein 3333 13583 23833
Re02.g08830 Uncharacterized protein 3334 13584 23834
G-patch domain protein (Spp2),
Re02.g08840 putative 3335 13585 23835
Re02.g08850 Uncharacterized protein 3336 13586 23836
60S ribosome biogenesis protein
Re02.g08860 Mak1 1 , putative 3337 13587 23837
Translation initiation factor EF-2
Re02.g08870 gamma subunit, putative 3338 13588 23838
Re02.g08880 60S ribosomal protein L34 3339 13589 23839 31241 32731
Re02.g08890 Uncharacterized protein 3340 13590 23840 CAAX prenyl protease, putative
Re02.g08900 EC=3.4.-.- 3341 13591 23841
Re02.g08910 Putative uncharacterized protein 3342 13592 23842 31242 32732
Re02.g08920 Uncharacterized protein 3343 13593 23843
Re02.g08930 Predicted protein 3344 13594 23844
Ribosome biogenesis protein
Re02.g08940 YTM1 3345 13595 23845
40S ribosomal protein S13
Re02.g08950 Fragment 3346 13596 23846
Peptidyl-prolyl cis-trans isomerase
Re02.g08960 EC=5.2.1.8 3347 13597 23847 31243 32733
ATP-dependent RNA helicase
Re02.g08970 dedl EC=3.6.4.13 3348 13598 23848
INO80 chromatin remodeling
Re02.g08980 complex 3349 13599 23849
Re02.g08990 Putative uncharacterized protein 3350 13600 23850
Re02.g09000 IMP cyclohydrolase 3351 13601 23851
Plasma membrane stress response
Re02.g09010 protein 3352 13602 23852
Re02.g09020 Clathrin heavy chain 3353 13603 23853
Re02.g09030 Pyruvate carboxylase EC=6.4.1.1 3354 13604 23854
Re02.g09040 Transposon, putative 3355 13605 23855
Re02.g09050 hypothetical protein 3356 13606 23856
Re02.g09060 Carboxylesterase, putative 3357 13607 23857 31244 32734
Re02.g09070 Pc13g07250 protein 3358 13608 23858
Re02.g09080 60S ribosomal protein L1 1 3359 13609 23859
Re02.g09090 Uncharacterized protein 3360 13610 23860
Re02.g09100 Uncharacterized protein 3361 1361 1 23861
Re02.g091 10 Amino acid transporter, putative 3362 13612 23862
Cation chloride cotransporter,
Re02.g09120 putative 3363 13613 23863
Re02.g09130 Mevalonate kinase 3364 13614 23864
Re02.g09140 Putative uncharacterized protein 3365 13615 23865
Re02.g09150 Putative uncharacterized protein 3366 13616 23866
Re02.g09160 Putative uncharacterized protein 3367 13617 23867 31245 32735
CaaX farnesyltransferase alpha
Re02.g09170 subunit Ram2 3368 13618 23868
Re02.g09180 L-serine dehydratase, putative 3369 13619 23869
Methionyl-tRNA synthetase,
Re02.g09190 putative EC=6.1.1.10 3370 13620 23870
Complex: human NXT1 binds to
RNA binding mRNA-export factor
Re02.g09200 TAP 3371 13621 23871
Re02.g09210 Uncharacterized protein 3372 13622 23872 31246 32736
Re02.g09220 60S ribosomal protein L38 3373 13623 23873
DNA polymerase delta subunit 2,
Re02.g09230 putative EC=2.7.7.7 3374 13624 23874
Oxidoreductase, 2-nitropropane
Re02.g09240 dioxygenase family, putative 3375 13625 23875 31247 32737 Re02.g09250 Putative uncharacterized protein 3376 13626 23876
Pitrilysin family metalloprotease
Re02.g09260 (Cym1), putative 3377 13627 23877
Re02.g09270 Putative uncharacterized protein 3378 13628 23878
Re02.g09280 Pc13g07470 protein 3379 13629 23879
Oxidoreductase, short chain
dehydrogenase/reductase family
Re02.g09290 superfamily 3380 13630 23880
Re02.g09300 Putative uncharacterized protein 3381 13631 23881
Re02.g09310 Putative uncharacterized protein 3382 13632 23882
Re02.g09320 Ornithine decarboxylase 3383 13633 23883
Re02.g09330 CobW domain protein 3384 13634 23884
2-hydroxychromene-2-carboxylate
Re02.g09340 isomerase, putative 3385 13635 23885
Re02.g09350 Putative uncharacterized protein 3386 13636 23886 31248 32738
Re02.g09360 Uncharacterized protein 3387 13637 23887 31249 32739
Re02.g09370 Uncharacterized protein 3388 13638 23888
Re02.g09380 Putative uncharacterized protein 3389 13639 23889
Re02.g09390 Uncharacterized protein 3390 13640 23890
Formation of crista junctions
Re02.g09400 protein 1 Precursor 3391 13641 23891
Re02.g09410 RAB GTPase Ypt5, putative 3392 13642 23892
Phosphoinositide phosphatase
Re02.g09420 (Sad ), putative 3393 13643 23893
Folylpolyglutamate synthase
Re02.g09430 EC=6.3.2.17 3394 13644 23894
Glycylpeptide N- tetradecanoyltransferase
Re02.g09440 EC=2.3.1.97 3395 13645 23895
Restriction of telomere capping
Re02.g09450 protein 5 3396 13646 23896
Re02.g09460 Uncharacterized protein 3397 13647 23897
Re02.g09470 Putative uncharacterized protein 3398 13648 23898
Elongation factor G, mitochondrial
Re02.g09480 Precursor 3399 13649 23899 31250 32740
Re02.g09490 Ribosomal protein 3400 13650 23900
Threonine dehydratase,
Re02.g09500 biosynthetic 3401 13651 23901
Altered inheritance of mitochondria
Re02.g09520 protein 31 , mitochondrial 3402 13652 23902
Re02.g09530 Uncharacterized protein 3403 13653 23903 31251 32741
Re02.g09540 hypothetical protein 3404 13654 23904
Succinate-semialdehyde
Re02.g09550 dehydrogenase Uga2, putative 3405 13655 23905
Re02.g09560 Putative uncharacterized protein 3406 13656 23906
Re02.g09570 Pescadillo homolog 3407 13657 23907
GPI transamidase component PIG-
Re02.g09580 LI, putative 3408 13658 23908 31252 32742
Re02.g09590 Putative uncharacterized protein 3409 13659 23909 Re02.g09600 Putative uncharacterized protein 3410 13660 23910
Re02.g09610 Putative uncharacterized protein 341 1 13661 2391 1
Raffinose synthase protein Sip1 ,
Re02.g09620 putative 3412 13662 23912
Re02.g09630 Uncharacterized protein 3413 13663 23913
DNA mismatch repair protein
Re02.g09640 Msh6, putative 3414 13664 23914
Re02.g09650 Histone h1.3., putative 3415 13665 23915
Re02.g09660 Uncharacterized protein 3416 13666 23916
Re02.g09670 Glutaminyl cyclase 3417 13667 23917 31253 32743
Re02.g09680 Uncharacterized protein 3418 13668 23918 31254 32744
60S ribosomal protein L27a,
Re02.g09690 putative 3419 13669 23919
Re02.g09700 hypothetical protein 3420 13670 23920
Re02.g09710 Uncharacterized protein 3421 13671 23921 31255 32745
Re02.g09720 Putative uncharacterized protein 3422 13672 23922
Re02.g09730 Uncharacterized protein 3423 13673 23923 31256 32746
Re02.g09740 Aspartyl-tRNA synthetase, putative 3424 13674 23924
Re02.g09750 hypothetical protein 3425 13675 23925
Re02.g09760 Uncharacterized protein 3426 13676 23926
Putative phosphatase like proteins
to the carbon terminal domain of
Re02.g09770 histone macroH2A1 3427 13677 23927
Re02.g09780 Nuclear movement protein NudC 3428 13678 23928
Re02.g09790 Uncharacterized protein 3429 13679 23929
Re02.g09800 hypothetical protein 3430 13680 23930 31257 32747
Re02.g09810 Putative uncharacterized protein 3431 13681 23931
Re02.g09820 Histone deacetylase RpdA/Rpd3 3432 13682 23932
Proteasome regulatory particle
Re02.g09830 subunit (RpnK), putative 3433 13683 23933
Mitochondrial translocase complex
Re02.g09840 component (Tim50), putative 3434 13684 23934
Re02.g09850 Uncharacterized protein Fragment 3435 13685 23935
Re02.g09860 L-allo-threonine aldolase, putative 3436 13686 23936
Re02.g09870 C6 transcription factor, putative 3437 13687 23937
Re02.g09880 F-box domain protein 3438 13688 23938
Re02.g09890 Uncharacterized protein 3439 13689 23939
Re02.g09900 C6 transcription factor 3440 13690 23940 31258 32748
Re02.g09910 Uncharacterized protein 3441 13691 23941
Re02.g09920 Predicted protein 3442 13692 23942
Deoxyribodipyrimidine photo-lyase
Re02.g09930 Phr1 , putative 3443 13693 23943
Re02.g09940 Uncharacterized protein 3444 13694 23944
Calcium/calmodulin-dependent
Re02.g09950 protein kinase, putative 3445 13695 23945
Re02.g09960 Macrolide phosphotransferase k 3446 13696 23946
Re02.g09970 Uncharacterized protein 3447 13697 23947
Re02.g09980 Predicted protein 3448 13698 23948
Re02.g09990 Sugar transporter 3449 13699 23949 Re02.g10000 Putative uncharacterized protein 3450 13700 23950
MFS monocarboxylate transporter,
Re02.g10010 putative 3451 13701 23951
Re02.g10020 hypothetical protein 3452 13702 23952 31259 32749
Re02.g10030 Putative uncharacterized protein 3453 13703 23953
Re02.g 10040 Histidine kinase J7 3454 13704 23954
Phenylalanyl-tRNA synthetase beta
Re02.g10050 chain cytoplasmic 3455 13705 23955
Methyltransferase LaeA-like,
putative (AFU orthologue
Re02.g10060 AFUA_8G01930) 3456 13706 23956
Re02.g10070 40S ribosomal protein S21 3457 13707 23957
Re02.g10080 NUDIX family hydrolase, putative 3458 13708 23958
lnosine-5'-monophosphate
Re02.g10090 dehydrogenase EC=1.1.1.205 3459 13709 23959
Re02.g10100 Pc18g05300 protein 3460 13710 23960
Re02.g101 10 Putative uncharacterized protein 3461 1371 1 23961
Ras GTPase activating protein,
Re02.g10120 putative 3462 13712 23962
Re02.g10130 ENTH domain containing protein 3463 13713 23963
Re02.g10140 Cell polarity protein, putative 3464 13714 23964
Re02.g10150 Putative uncharacterized protein 3465 13715 23965
Re02.g10160 HMG-CoA reductase 3466 13716 23966
Re02.g10170 hypothetical protein 3467 13717 23967
Re02.g10180 Uncharacterized protein 3468 13718 23968 31260 32750
Re02.g10190 Uncharacterized protein 3469 13719 23969
Re02.g10200 SH3 domain protein 3470 13720 23970
Re02.g10210 Uncharacterized protein 3471 13721 23971
Peptidyl-prolyl cis-trans isomerase
Re02.g 10220 EC=5.2.1.8 3472 13722 23972
Re02.g10230 Putative uncharacterized protein 3473 13723 23973 31261 32751
Exosome complex endonuclease
Re02.g 10240 1 , putative 3474 13724 23974
DNA excision repair protein
Re02.g 10250 (Rad26L), putative 3475 13725 23975
Re02.g 10260 Uncharacterized protein 3476 13726 23976
Transcription/RNA-processing
Re02.g10270 factor Ssu72 3477 13727 23977
Re02.g10280 Acyl-CoA dehydrogenase, putative 3478 13728 23978
Isochorismatase family hydrolase,
Re02.g10290 putative 3479 13729 23979
Re02.g10300 Putative uncharacterized protein 3480 13730 23980
Oxysterol binding protein (Osh7),
Re02.g10310 putative 3481 13731 23981
Re02.g10320 Histone deacetylase EC=3.5.1.98 3482 13732 23982
Re02.g10330 Allergen Asp f 4 3483 13733 23983 31262 32752
Re02.g 10340 Amidase signature (AS) enzyme 3484 13734 23984
Re02.g10350 Allantoin permease 3485 13735 23985
Re02.g10360 Uncharacterized protein 3486 13736 23986 Re02.g10370 CobW protein 3487 13737 23987
Re02.g10380 Uncharacterized protein 3488 13738 23988
Phenylalanine ammonia-lyase
Re02.g10390 EC=4.3.1.24 3489 13739 23989
Re02.g 10400 Metabolite transport protein GIT1 3490 13740 23990
Plasma membrane low affinity zinc
Re02.g10410 ion transporter, putative 3491 13741 23991
Mitochondrial import receptor
Re02.g 10420 subunit (Tom37), putative 3492 13742 23992 31263 32753
Re02.g 10430 Uncharacterized protein 3493 13743 23993 31264 32754
Re02.g 10440 FK506-binding protein 2 3494 13744 23994 31265 32755
Heme/steroid binding protein,
Re02.g 10450 putative 3495 13745 23995 31266 32756
Re02.g 10460 Protein phosphatase 2C, putative 3496 13746 23996 31267 32757
Re02.g 10470 hypothetical protein 3497 13747 23997
Acetamidase/formamidase family
Re02.g 10480 protein 3498 13748 23998
Re02.g 10490 ATP-dependent DNA helicase 3499 13749 23999
Re02.g10500 hypothetical protein 3500 13750 24000
Re02.g10510 hypothetical protein 3501 13751 24001
Re02.g 10520 Putative uncharacterized protein 3502 13752 24002 31268 32758
Re02.g10530 Cinnamoyl-CoA reductase 3503 13753 24003
Re02.g 10540 G1/S-specific cyclin Cln1 , putative 3504 13754 24004
Re02.g 10550 hypothetical protein 3505 13755 24005 31269 32759
Small nucleolar ribonucleoprotein
Re02.g 10560 complex subunit, putative 3506 13756 24006
Serine/threonine-protein
Re02.g10570 phosphatase EC=3.1.3.16 3507 13757 24007
Re02.g10580 Uncharacterized protein 3508 13758 24008
Re02.g10590 Putative uncharacterized protein 3509 13759 24009
Re02.g10600 Predicted protein 3510 13760 24010
Re02.g10610 DUF52 domain protein 351 1 13761 2401 1
Alpha- 1 ,3-glucanase/mutanase,
Re02.g 10620 putative 3512 13762 24012 31270 32760
Catalytic activity: gentisate 1
Re02.g10630 EC=1.13.1 1.4 3513 13763 24013
Re02.g 10640 C6 transcription factor, putative 3514 13764 24014
5-carboxymethyl-2-
Re02.g 10650 hydroxymuconate isomerase 3515 13765 24015
Re02.g 10660 Putative uncharacterized protein 3516 13766 24016 31271 32761
Re02.g10670 Uncharacterized protein 3517 13767 24017
Re02.g10680 Putative uncharacterized protein 3518 13768 24018
Re02.g10690 Uncharacterized protein 3519 13769 24019
Re02.g10700 NRPS-like enzyme, putative 3520 13770 24020
Re02.g10710 Putative uncharacterized protein 3521 13771 24021
Re02.g10720 Putative uncharacterized protein 3522 13772 24022
Benzoate 4-monooxygenase
Re02.g10730 cytochrome P450, putative 3523 13773 24023 31272 32762
Re02.g 10740 hypothetical protein 3524 13774 24024 Re02.g10750 Peptidase (PNG1 ), putative 3525 13775 24025
Re02.g10760 hypothetical protein 3526 13776 24026
Alpha.alpha-trehalose-phosphate
Re02.g10770 synthase subunit, putative 3527 13777 24027
Alpha.alpha-trehalose phosphate
synthase subunit, putative
Re02.g10780 EC=2.4.1.15 3528 13778 24028
Re02.g10790 Pc21 g14030 protein 3529 13779 24029
Chromatin assembly factor 1
Re02.g10800 subunit B, putative 3530 13780 24030
Re02.g10810 Putative uncharacterized protein 3531 13781 24031
Re02.g10820 Putative uncharacterized protein 3532 13782 24032
NADH:flavin oxidoreductase/NADH
Re02.g10830 oxidase family protein 3533 13783 24033
Re02.g 10840 Putative uncharacterized protein 3534 13784 24034
Re02.g10850 Uncharacterized protein 3535 13785 24035
Re02.g10860 GPR/FUN34 family protein 3536 13786 24036
Re02.g10870 Putative uncharacterized protein 3537 13787 24037
Re02.g10880 Predicted protein 3538 13788 24038
Re02.g10890 Predicted protein 3539 13789 24039
Re02.g10900 Pc13g00930 protein 3540 13790 24040
Re02.g10910 Uncharacterized protein 3541 13791 24041
Re02.g10920 Predicted protein 3542 13792 24042
Re02.g10930 Uncharacterized protein 3543 13793 24043
Re02.g 10940 Uncharacterized protein 3544 13794 24044
Re02.g10950 ENTH domain protein 3545 13795 24045
Re02.g10960 Uncharacterized protein Fragment 3546 13796 24046
Re02.g10970 40S ribosomal protein S1 1 3547 13797 24047
Re02.g10980 Uncharacterized protein 3548 13798 24048
Re02.g10990 C6 transcription factor, putative 3549 13799 24049
Re02.g1 1000 hypothetical protein 3550 13800 24050 31273 32763
Re02.g1 1010 hypothetical protein 3551 13801 24051
Re02.g1 1020 Putative uncharacterized protein 3552 13802 24052
Re02.g1 1030 BZIP transcription factor, putative 3553 13803 24053
Re02.g 1 1040 Endo mannanase, GH76 family 3554 13804 24054 31274 32764
Cell wall integrity signaling protein
Re02.g1 1050 Lsp1/Pil1 , putative 3555 13805 24055
Re02.g1 1060 DNA excision repair protein Rad2 3556 13806 24056
Re02.g1 1070 WD repeat protein 3557 13807 24057
15-hydroxyprostaglandin
Re02.g1 1080 dehydrogenase, putative 3558 13808 24058
Endo beta 1 ,4 glucanase
Re02.g1 1090 EC=3.2.1.4 EC=3.2.1.4 3559 13809 24059 31275 32765
Re02.g1 1 100 Uncharacterized protein 3560 13810 24060
Re02.g1 1 1 10 Uncharacterized protein 3561 1381 1 24061 31276 32766
Re02.g1 1 120 Integral membrane protein 3562 13812 24062 31277 32767
Re02.g1 1 130 Uncharacterized protein 3563 13813 24063
Re02.g1 1 140 Uncharacterized protein Fragment 3564 13814 24064
Re02.g1 1 150 Methyltransferase, putative 3565 13815 24065 Re02.g1 1 160 Putative uncharacterized protein 3566 13816 24066
1 -phosphatidylinositol-3-phosphate
Re02.g1 1 170 5-kinase 3567 13817 24067
Re02.g1 1 180 Pyruvate kinase EC=2.7.1.40 3568 13818 24068
Re02.g1 1 190 Putative uncharacterized protein 3569 13819 24069 31278 32768
Re02.g1 1200 Uncharacterized protein 3570 13820 24070
Re02.g1 1210 Predicted protein 3571 13821 24071
Re02.g1 1220 Putative uncharacterized protein 3572 13822 24072
Re02.g1 1230 Serine/threonine protein kinase 3573 13823 24073
Re02.g 1 1240 Uncharacterized protein 3574 13824 24074
Re02.g1 1250 hypothetical protein 3575 13825 24075
Re02.g1 1260 Putative uncharacterized protein 3576 13826 24076
Isocitrate dehydrogenase LysB
Re02.g1 1270 EC=1.1.1.87 3577 13827 24077
Re02.g1 1280 Uncharacterized protein 3578 13828 24078
Re02.g1 1290 Dipeptidase, putative 3579 13829 24079
Re02.g1 1300 Putative uncharacterized protein 3580 13830 24080
NAD dependent
Re02.g1 1310 epimerase/dehydratase, putative 3581 13831 24081
Re02.g1 1320 Putative uncharacterized protein 3582 13832 24082
Re02.g1 1330 Kynurenine 3-monooxygenase 3583 13833 24083
Methionine aminopeptidase
Re02.g 1 1340 EC=3.4.1 1.18 3584 13834 24084
Re02.g1 1350 MFS multidrug transporter 3585 13835 24085
Re02.g1 1360 hypothetical protein 3586 13836 24086
Re02.g1 1370 EF hand domain protein 3587 13837 24087
mRNA splicing factor (Prp17),
Re02.g1 1380 putative 3588 13838 24088
Re02.g1 1390 ABC transporter 3589 13839 24089 31279 32769
Re02.g1 1400 Aminotransferase, putative 3590 13840 24090
Re02.g1 1430 C6 transcription factor, putative 3591 13841 24091
Re02.g 1 1440 GPI anchored protein, putative 3592 13842 24092 31280 32770
Long-chain fatty acid transporter,
Re02.g1 1450 putative 3593 13843 24093
Re02.g1 1460 Putative uncharacterized protein 3594 13844 24094 31281 32771
Re02.g1 1470 ZZ type zinc finger protein 3595 13845 24095
Fungal specific transcription factor,
Re02.g1 1480 putative 3596 13846 24096
Sreptomyces cyclase/dehydrase
Re02.g1 1490 family protein 3597 13847 24097
Re02.g1 1500 Putative uncharacterized protein 3598 13848 24098
Re02.g1 1510 Putative uncharacterized protein 3599 13849 24099 31282 32772
GPI transamidase component PIG-
Re02.g 1 1520 S, putative 3600 13850 24100
Re02.g1 1530 Uncharacterized protein 3601 13851 24101
IZH family channel protein (Izh3),
Re02.g 1 1540 putative 3602 13852 24102
Re02.g 1 1550 Putative uncharacterized protein 3603 13853 24103
Re02.g 1 1560 Actin binding protein 3604 13854 24104 Re02.g1 1570 Uncharacterized protein 3605 13855 24105 31283 32773
Re02.g1 1580 hypothetical protein 3606 13856 24106 31284 32774
Re02.g1 1590 hypothetical protein 3607 13857 24107
Re02.g1 1600 Uncharacterized protein 3608 13858 24108
Monosaccharide-P-dolichol
Re02.g1 1610 utilization protein, putative 3609 13859 24109
Re02.g1 1620 hypothetical protein 3610 13860 241 10
RNA polymerase II mediator
complex component Med8,
Re02.g1 1630 putative 361 1 13861 241 1 1
Re02.g 1 1640 Uncharacterized protein 3612 13862 241 12 31285 32775
LaeA-like methyltransferase,
Re02.g1 1650 putative 3613 13863 241 13
Re02.g1 1660 Uncharacterized protein 3614 13864 241 14
Re02.g1 1670 hypothetical protein 3615 13865 241 15
Re02.g1 1680 hypothetical protein 3616 13866 241 16
Re02.g1 1690 hypothetical protein 3617 13867 241 17
Function: Tto1 can transpose
autonomously through reverse
transcription EC=2.7.7.49
EC=2.7.7.49 EC=2.7.7.49
Re02.g1 1700 EC=2.7.7.49 3618 13868 241 18
Re02.g1 1710 Putative uncharacterized protein 3619 13869 241 19
Re02.g1 1720 Mating locus protein, putative 3620 13870 24120 31286 32776
Re02.g1 1730 Mating-type protein MAT1 -2 3621 13871 24121
Re02.g 1 1740 C2H2 transcription factor 3622 13872 24122
Re02.g1 1750 Uncharacterized protein 3623 13873 24123
Re02.g1 1760 hypothetical protein 3624 13874 24124
Re02.g1 1770 Putative uncharacterized protein 3625 13875 24125
Re02.g1 1780 Putative uncharacterized protein 3626 13876 24126 31287 32777
Mannose-6-phosphate isomerase,
Re02.g1 1790 class I 3627 13877 24127
Re02.g1 1800 Putative uncharacterized protein 3628 13878 24128
Patatin family phospholipase,
Re02.g1 1810 putative 3629 13879 24129
Re02.g1 1820 Pc16g07530 protein 3630 13880 24130
Re02.g1 1830 Uncharacterized protein 3631 13881 24131
26S proteasome regulatory subunit
Re02.g 1 1840 Rpn2, putative 3632 13882 24132
Catalytic activity: acyl-CoA + ETF
Re02.g1 1850 <=> 2 EC=1.3.99.13 3633 13883 24133
Transcription elongation factor
Re02.g1 1860 SPT5 3634 13884 24134
mRNA capping nucleoside-
Re02.g1 1870 triphosphatase, putative 3635 13885 24135
Re02.g1 1880 Acyltransferase, putative 3636 13886 24136
Pantetheine-phosphate
Re02.g1 1890 adenylyltransferase family protein 3637 13887 24137 31288 32778
Re02.g1 1900 WD repeat protein 3638 13888 24138 Re02.g1 1910 F-box domain protein 3639 13889 24139
Re02.g1 1920 Retinal dehydrogenase 2 3640 13890 24140
Re02.g1 1930 Uncharacterized protein 3641 13891 24141
Re02.g 1 1940 Uncharacterized protein 3642 13892 24142
Re02.g1 1950 MFS multidrug transporter, putative 3643 13893 24143
Re02.g1 1960 Peroxiredoxin PRX1 3644 13894 24144
Putative uncharacterized protein
Re02.g1 1970 Fragment 3645 13895 24145
Calcium homeostasis protein
Re02.g1 1980 Regucalcin, putative 3646 13896 24146
Re02.g1 1990 hypothetical protein 3647 13897 24147
Re02.g12000 3-phytase A 3648 13898 24148
Re02.g12010 Phytase EC=3.1.3.8 3649 13899 24149 31289 32779
Re02.g12020 hypothetical protein 3650 13900 24150
Re02.g12030 Glutathione S-transferase, putative 3651 13901 24151
Function: Rattus norvegicus CLN2
Re02.g 12040 is a lysosomal protease Precursor 3652 13902 24152 31290 32780
Re02.g12050 Uncharacterized protein 3653 13903 24153
GPI-anchored cell surface
Re02.g12060 glycoprotein, putative 3654 13904 24154
Oligosaccharyltransferase subunit
Re02.g12070 ribophorin II, putative 3655 13905 24155 31291 32781
Re02.g12080 Putative uncharacterized protein 3656 13906 24156
Function: brIA has a direct role in
Re02.g12090 the regulation of cell cycle genes 3657 13907 24157
Re02.g12100 Uncharacterized protein 3658 13908 24158
Re02.g121 10 Pc18g02850 protein Precursor 3659 13909 24159 31292 32782
Short chain dehydrogenase,
Re02.g12120 putative 3660 13910 24160
Cytochrome P450 pisatin
Re02.g12130 demethylase, putative 3661 1391 1 24161 31293 32783
Re02.g12140 Lysophospholipase Plb1 3662 13912 24162 31294 32784
Re02.g12150 Putative uncharacterized protein 3663 13913 24163
Phospho-2-dehydro-3-
Re02.g12160 deoxyheptonate aldolase, class II 3664 13914 24164
Re02.g12170 Putative uncharacterized protein 3665 13915 24165
Re02.g12180 Uncharacterized protein 3666 13916 24166
Putative enzymes related to aldose
Re02.g12190 1 -epimerase 3667 13917 24167
Re02.g12200 Aldo-keto reductase family protein 3668 13918 24168
Telomere length regulator protein
Re02.g12210 (Ri l ), putative 3669 13919 24169
Re02.g 12220 Synembryn 3670 13920 24170
DUF757 domain protein
Re02.g12230 (AFU.orthologue AFUA_4G08810) 3671 13921 24171
Re02.g 12240 Pc18g03100 protein 3672 13922 24172
Re02.g 12250 Putative uncharacterized protein 3673 13923 24173
Re02.g 12260 Putative uncharacterized protein 3674 13924 24174
Re02.g12270 CDK-activating kinase assembly 3675 13925 24175 factor MAT1
Re02.g12280 Uncharacterized protein 3676 13926 24176
Re02.g12290 Protein kinase 3677 13927 24177
Re02.g12300 Nucleolar GTP-binding protein 2 3678 13928 24178
Re02.g12310 Similar to An04g03800 3679 13929 24179
GPI anchored cell wall protein,
Re02.g12320 putative 3680 13930 24180 31295 32785
Re02.g12330 PAP2 domain protein 3681 13931 24181
Re02.g 12340 Putative uncharacterized protein 3682 13932 24182
Molybdenum cofactor sulfurase
Re02.g12350 protein (HxB), putative 3683 13933 24183
Re02.g12360 60S ribosomal protein L25, putative 3684 13934 24184
mRNA splicing protein (Prp39),
Re02.g12370 putative 3685 13935 24185
Re02.g12380 DEAD/DEAH box helicase, putative 3686 13936 24186
Re02.g12390 Aminopeptidase 3687 13937 24187
Re02.g 12400 High affinity methionine permease 3688 13938 24188
Serine/threonine protein kinase
Re02.g12410 (Pdd7p), putative 3689 13939 24189
Re02.g 12420 hypothetical protein 3690 13940 24190
Phosphatidate cytidylyltransferase,
Re02.g 12430 putative 3691 13941 24191
Re02.g 12440 Putative ATPase 3692 13942 24192
C2H2 transcription factor (Seb1 ),
Re02.g 12450 putative 3693 13943 24193
Re02.g 12460 hypothetical protein 3694 13944 24194
Re02.g 12470 Thioredoxin, putative 3695 13945 24195
Re02.g 12480 Diphthamide biosynthesis protein 4 3696 13946 24196
Cytochrome c peroxidase Ccp1 ,
Re02.g 12490 putative EC=1.1 1.1.5 3697 13947 24197
Re02.g12500 Putative uncharacterized protein 3698 13948 24198
GTPase activating protein for Ar ,
Re02.g12510 putative 3699 13949 24199
Re02.g 12520 Uncharacterized protein 3700 13950 24200
Re02.g12530 Mannosyltransferase 3701 13951 24201 31296 32786
L-ornithine aminotransferase Car2,
Re02.g 12540 putative EC=2.6.1.13 3702 13952 24202
Re02.g 12550 Uncharacterized protein 3703 13953 24203
Re02.g 12560 PLAC8 family protein 3704 13954 24204
Re02.g12570 Uncharacterized protein 3705 13955 24205
Re02.g12580 hypothetical protein 3706 13956 24206 31297 32787
Re02.g12590 Putative uncharacterized protein 3707 13957 24207
Re02.g12600 Putative uncharacterized protein 3708 13958 24208
Secretory component protein shr3,
Re02.g12610 putative 3709 13959 24209 31298 32788
Re02.g 12620 pH response protein PalF 3710 13960 24210
Re02.g12630 Predicted protein 371 1 13961 2421 1 31299 32789
Re02.g 12640 Putative uncharacterized protein 3712 13962 24212
Re02.g 12650 WD repeat protein 3713 13963 24213 Re02.g 12660 Putative uncharacterized protein 3714 13964 24214
Re02.g12670 Uncharacterized protein 3715 13965 24215
Re02.g12680 hypothetical protein 3716 13966 24216
C6 sexual development
Re02.g12690 transcription factor NosA 3717 13967 24217
Re02.g12700 SAM and PH domain protein 3718 13968 24218
NACHT and Ankyrin domain
Re02.g12710 protein 3719 13969 24219
Re02.g12720 Autophagy protein Apg5, putative 3720 13970 24220
Re02.g12730 Uncharacterized protein 3721 13971 24221
Re02.g 12740 hypothetical protein 3722 13972 24222
Alpha/beta hydrolase family
Re02.g12750 protein, putative 3723 13973 24223 31300 32790
Re02.g12760 Pantothenate transporter, putative 3724 13974 24224
Re02.g12770 WD repeat protein 3725 13975 24225
Maleylacetate reductase, putative
Re02.g12780 EC=1.3.1.32 3726 13976 24226
Diphthamide biosynthesis protein
Re02.g12790 Dph2, putative 3727 13977 24227
Re02.g12800 Uncharacterized protein 3728 13978 24228
Re02.g12810 Uncharacterized protein 3729 13979 24229 31301 32791
Polarized growth protein (Boi2),
Re02.g12820 putative 3730 13980 24230
Re02.g12830 MIZ zinc finger domain protein 3731 13981 24231
RNA binding protein (Rbm8A),
Re02.g 12840 putative 3732 13982 24232
Re02.g12850 Glycosyl hydrolase, putative 3733 13983 24233 31302 32792
ATPase inhibitor, mitochondrial,
Re02.g12860 putative 3734 13984 24234
Re02.g12870 hypothetical protein 3735 13985 24235
Re02.g12880 14-3-3 family protein ArtA, putative 3736 13986 24236
Re02.g12890 hypothetical protein 3737 13987 24237
Re02.g12900 BZIP transcription factor, putative 3738 13988 24238
Re02.g12910 Nucleoporin Nsp1 , putative 3739 13989 24239
Re02.g12920 Uncharacterized protein 3740 13990 24240
Phytanoyl-CoA dioxygenase family
Re02.g12930 protein 3741 13991 24241
Re02.g 12940 Alpha-amylase, putative 3742 13992 24242 31303 32793
Re02.g12950 Bax Inhibitor family protein 3743 13993 24243
Re02.g12960 Protein cgil 21 3744 13994 24244
Structure-specific endonuclease
Re02.g12970 subunit slx4 3745 13995 24245
Re02.g12980 hypothetical protein 3746 13996 24246
Cyclic nucleotide-binding domain
Re02.g12990 protein 3747 13997 24247
Re02.g13000 Putative uncharacterized protein 3748 13998 24248
Re02.g13010 Putative uncharacterized protein 3749 13999 24249
Re02.g13020 Kinesin family protein 3750 14000 24250
Re02.g13030 Peptide methionine sulfoxide 3751 14001 24251 reductase
Re02.g 13040 Polyketide synthase, putative 3752 14002 24252
Re02.g13050 Putative uncharacterized protein 3753 14003 24253
Re02.g13060 Polyketide synthase 3754 14004 24254
Re02.g13070 Uncharacterized protein 3755 14005 24255
Re02.g13080 Similar to An07g07550 3756 14006 24256
Transposon-encoded proteins with
Re02.g13090 TYA 3757 14007 24257
Glycosyl hydrolases family 16
Re02.g13100 protein 3758 14008 24258 31304 32794
Aspergillus niger contig
Re02.g131 10 An1 1 c0210, genomic contig 3759 14009 24259 31305 32795
OPT family Small oligopeptide
Re02.g13120 transporter Fragment 3760 14010 24260
Fructosyl amine: oxygen
Re02.g13130 oxidoreductase 3761 1401 1 24261 31306 32796
Re02.g13140 Uncharacterized protein 3762 14012 24262
Re02.g13150 Alkaline phosphatase Pho8 3763 14013 24263
Re02.g13160 Putative uncharacterized protein 3764 14014 24264
Vacuolar ABC heavy metal
Re02.g13170 transporter (Hmt1 ), putative 3765 14015 24265
Re02.g13180 hypothetical protein 3766 14016 24266
Re02.g13190 WD repeat protein 3767 14017 24267
Re02.g13200 Uncharacterized protein 3768 14018 24268
Re02.g13210 Cactin, putative 3769 14019 24269
Re02.g 13220 Forkhead domain protein 3770 14020 24270
Ribosomal protein L34 protein,
Re02.g13230 putative 3771 14021 24271
Re02.g 13240 Uncharacterized protein Fragment 3772 14022 24272
Re02.g 13250 MYB DNA-binding domain protein 3773 14023 24273
Re02.g 13260 Cytochrome c subunit Vb, putative 3774 14024 24274 31307 32797
Re02.g13270 Nucleoside transporter, putative 3775 14025 24275
Putative uncharacterized protein
Re02.g13280 An07g07370 3776 14026 24276
Re02.g13290 Uncharacterized protein 3777 14027 24277
Re02.g13300 Putative uncharacterized protein 3778 14028 24278
Re02.g13310 Putative uncharacterized protein 3779 14029 24279
Re02.g13320 Putative uncharacterized protein 3780 14030 24280
Re02.g13330 Putative uncharacterized protein 3781 14031 24281
Re02.g 13340 hypothetical protein 3782 14032 24282 31308 32798
Re02.g13350 Putative uncharacterized protein 3783 14033 24283
Re02.g13360 Uncharacterized protein 3784 14034 24284
Re02.g13370 Translation factor pelota, putative 3785 14035 24285
Re02.g13380 Pc18g01690 protein 3786 14036 24286
Re02.g13390 Putative uncharacterized protein 3787 14037 24287
Re02.g 13400 40S ribosomal protein S19 3788 14038 24288
Putative uncharacterized protein
Re02.g13410 An18g04170 EC=3.1.3.33 3789 14039 24289
Re02.g 13420 Mitochondrial dihydroxy acid 3790 14040 24290 dehydratase, putative
Re02.g 13430 Uncharacterized protein 3791 14041 24291 31309 32799
Peroxisome biosynthesis protein
Re02.g 13440 (Peroxin-2), putative 3792 14042 24292
Acid phosphatase PHOa
Re02.g 13450 (AFlLorthologue AFUAJ G03570) 3793 14043 24293 31310 32800
Re02.g 13460 Putative uncharacterized protein 3794 14044 24294
Re02.g 13470 Uncharacterized protein 3795 14045 24295
Re02.g 13480 Uncharacterized protein 3796 14046 24296
Similar to 9-cis-epoxycarotenoid
Re02.g 13490 dioxygenase 3797 14047 24297
Re02.g13500 Putative uncharacterized protein 3798 14048 24298
Re02.g13510 Importin 1 1 3799 14049 24299
Re02.g13530 Predicted protein 3800 14050 24300
Re02.g 13540 Vanillin dehydrogenase, putative 3801 14051 24301
GPI anchored serine-threonine rich
Re02.g 13550 protein 3802 14052 24302 3131 1 32801
Re02.g 13560 Uncharacterized protein 3803 14053 24303
Re02.g13570 Uncharacterized protein 3804 14054 24304
Re02.g13580 hypothetical protein 3805 14055 24305
Re02.g13590 Putative uncharacterized protein 3806 14056 24306
Re02.g13600 hypothetical protein 3807 14057 24307
Re02.g13610 Acid phosphatase, putative 3808 14058 24308
Re02.g 13620 Putative uncharacterized protein 3809 14059 24309
4-carboxymuconolactone
Re02.g13630 decarboxylase, putative 3810 14060 24310
Re02.g 13640 Uncharacterized protein 381 1 14061 2431 1
C2H2 finger domain-containing
Re02.g 13650 protein 3812 14062 24312
Re02.g 13660 UPF0136 domain protein 3813 14063 24313 31312 32802
Re02.g13670 MFS transporter, putative 3814 14064 24314
Re02.g13680 Putative uncharacterized protein 3815 14065 24315
Re02.g13690 Uncharacterized protein 3816 14066 24316
Re02.g13700 DUF726 domain protein 3817 14067 24317
Cyclohexanone 1 ,2-
Re02.g13710 monooxygenase 3818 14068 24318
Re02.g13720 Predicted protein 3819 14069 24319
Re02.g13730 hypothetical protein 3820 14070 24320
Re02.g 13740 C6 finger domain protein, putative 3821 14071 24321
Re02.g13750 Uncharacterized protein 3822 14072 24322
Re02.g13760 Uncharacterized protein 3823 14073 24323
Re02.g13770 hypothetical protein 3824 14074 24324
Extracellular developmental signal
Re02.g13780 biosynthesis protein FluG 3825 14075 24325
Mannosylphosphorylation protein
Re02.g13790 (Mnn4), putative 3826 14076 24326 31313 32803
Re02.g13800 C6 transcription factor, putative 3827 14077 24327
Oligosaccharyl transferase subunit
Re02.g13810 Dad1 , putative 3828 14078 24328 mRNA splicing factor RNA helicase
Re02.g13820 (Prp16), putative 3829 14079 24329
Re02.g13830 Prefoldin subunit 2, putative 3830 14080 24330
CCAAT-binding factor complex
Re02.g 13840 subunit HapC 3831 14081 24331
Re02.g13850 Acetamidase regulatory protein 3832 14082 24332
Re02.g13860 Putative uncharacterized protein 3833 14083 24333
Re02.g13870 Uncharacterized protein 3834 14084 24334
Re02.g13880 Alpha/beta hydrolase, putative 3835 14085 24335
Re02.g13890 Spo7-like protein 3836 14086 24336
Re02.g13900 Uncharacterized protein 3837 14087 24337 31314 32804
Re02.g13910 Uncharacterized protein 3838 14088 24338
Re02.g13920 Predicted protein 3839 14089 24339 31315 32805
Re02.g13930 hypothetical protein 3840 14090 24340
Re02.g 13940 Uncharacterized protein 3841 14091 24341 31316 32806
Re02.g13950 Putative uncharacterized protein 3842 14092 24342
Re02.g13960 DNA replication licensing factor 3843 14093 24343
Translation regulator (Cya5),
Re02.g13970 putative 3844 14094 24344
Signal recognition particle subunit
Re02.g13980 SRP68 3845 14095 24345
Cytochrome P450 sterol C-22
Re02.g13990 desaturase, putative 3846 14096 24346
Re02.g14000 Uncharacterized protein Fragment 3847 14097 24347
Mitochondrial translation initiation
Re02.g14010 factor IF-2, putative 3848 14098 24348
Re02.g14020 Uncharacterized protein 3849 14099 24349
Re02.g14030 TBC domain protein 3850 14100 24350
Re02.g 14040 hypothetical protein 3851 14101 24351 31317 32807
Re02.g14050 Yip1 domain family 3852 14102 24352
Re02.g14060 Putative uncharacterized protein 3853 14103 24353
Eukaryotic translation initiation
Re02.g14070 factor elF-5A 3854 14104 24354
GARP complex subunit (Sac2),
Re02.g14080 putative 3855 14105 24355
FAD dependent oxidoreductase,
Re02.g14090 putative 3856 14106 24356
Similarity to hypothetical protein
Re02.g14100 encoded by An01 g14430 3857 14107 24357
Re02.g141 10 hypothetical protein 3858 14108 24358 31318 32808
Re02.g14120 hypothetical protein 3859 14109 24359
Re02.g14130 Putative uncharacterized protein 3860 141 10 24360 31319 32809
Re02.g14140 C2H2 transcription factor, putative 3861 141 1 1 24361
Re02.g14150 Putative uncharacterized protein 3862 141 12 24362
Re02.g14160 hypothetical protein 3863 141 13 24363
Re02.g14170 Adenylosuccinate lyase, putative 3864 141 14 24364
Re02.g14180 3-ketoacyl-CoA thiolase B, putative 3865 141 15 24365
Succinyl-CoA:3-ketoacid-
Re02.g14190 coenzyme A transferase 3866 141 16 24366 EC=2.8.3.5
Aryl-alcohol oxidase; vanillyl-
Re02.g14200 alcohol oxidase EC=1.1.3.38 3867 141 17 24367
Alpha methylacyl-CoA racemase,
Re02.g14210 putative 3868 141 18 24368
Re02.g 14220 Uncharacterized protein 3869 141 19 24369
Re02.g14230 Uncharacterized protein 3870 14120 24370
Fungal specific transcription factor,
Re02.g 14240 putative 3871 14121 24371
Isocitrate/isopropylmalate
Re02.g 14250 dehydrogenase 3872 14122 24372
Re02.g 14260 C6 finger domain protein, putative 3873 14123 24373
Re02.g14270 Polyadenylate-binding protein 3874 14124 24374
Re02.g14280 E3 ubiquitin protein ligase 3875 14125 24375
Re02.g14290 50S ribosomal protein YmL27 3876 14126 24376
Small nucleolar ribonucleoprotein
Re02.g14300 complex subunit Utp14, putative 3877 14127 24377
Re02.g14310 Endo-1 ,3-beta-glucanase Engll 3878 14128 24378 31320 32810
Calcium ion transporter Vcx1 ,
Re02.g14320 putative 3879 14129 24379
Plasma membrane phosphate
Re02.g14330 transporter Pho87, putative 3880 14130 24380
Ser/Thr protein phosphatase family
Re02.g 14340 protein 3881 14131 24381
Re02.g14350 40S ribosomal protein S8 3882 14132 24382
Dedicator of cytokinesis domain
Re02.g14360 protein, putative 3883 14133 24383 31321 3281 1
Exocyst complex component Sec3,
Re02.g14370 putative 3884 14134 24384
Re02.g14380 Putative uncharacterized protein 3885 14135 24385
Re02.g14390 hypothetical protein 3886 14136 24386
Re02.g 14400 Uncharacterized protein 3887 14137 24387 31322 32812
Cytochrome P450
Re02.g14410 monooxygenase, putative 3888 14138 24388 31323 32813
Re02.g 14420 Phosphoglycerate mutase, putative 3889 14139 24389
Mitochondrial 37S ribosomal
Re02.g 14430 protein YmS-T 3890 14140 24390
Re02.g 14440 Transposase 3891 14141 24391
Re02.g 14450 Putative uncharacterized protein 3892 14142 24392
Re02.g 14460 Putative uncharacterized protein 3893 14143 24393
Re02.g 14470 Putative uncharacterized protein 3894 14144 24394 31324 32814
Siderophore biosynthesis protein,
Re02.g 14480 putative 3895 14145 24395
Re02.g 14490 60S ribosomal protein L30, putative 3896 14146 24396
Re02.g14500 Cyclin (Pcl1 ), putative 3897 14147 24397
Re02.g14510 hypothetical protein 3898 14148 24398
C-8 sterol isomerase (Erg-1 ),
Re02.g 14520 putative 3899 14149 24399
Re02.g14530 PP-loop ATPase superfamily 3900 14150 24400 protein, putative
Re02.g 14540 Putative uncharacterized protein 3901 14151 24401
Ras guanyl-nucleotide exchange
Re02.g 14550 factor RasGEF, putative 3902 14152 24402
Re02.g 14560 HIT finger domain protein, putative 3903 14153 24403
Re02.g14570 Putative uncharacterized protein 3904 14154 24404
Re02.g14580 NifU-related protein 3905 14155 24405
Re02.g14590 PSP1 domain protein 3906 14156 24406
Re02.g14600 Ribosomal protein L15 3907 14157 24407
Re02.g14610 Ubiquitin-protein ligase 3908 14158 24408
Alcohol dehydrogenase, zinc-
Re02.g 14620 containing, putative 3909 14159 24409
Re02.g14630 Uncharacterized protein 3910 14160 24410
RING finger domain protein,
Re02.g 14640 putative 3911 14161 24411
Transcriptional regulator Ngg1 ,
Re02.g 14650 putative 3912 14162 24412
Nitrogen permease regulator Npr2,
Re02.g 14660 putative 3913 14163 24413
Re02.g14670 hypothetical protein 3914 14164 24414
Re02.g14680 Putative uncharacterized protein 3915 14165 24415
Re02.g14690 Uncharacterized protein 3916 14166 24416
Re02.g14700 Predicted protein 3917 14167 24417
Re02.g14710 Predicted protein 3918 14168 24418
Re02.g14720 Predicted protein 3919 14169 24419
Re02.g14730 Urease EC=3.5.1.5 3920 14170 24420
Re02.g 14740 HMG box protein, putative 3921 14171 24421
NADH-cytochrome b5 reductase 2
Re02.g14750 EC=1.6.2.2 3922 14172 24422
Re02.g14760 60S ribosomal protein L20 3923 14173 24423
Re02.g14770 Putative uncharacterized protein 3924 14174 24424
Re02.g14780 Putative uncharacterized protein 3925 14175 24425
Regulator of gluconeogenesis
Re02.g14790 Rmd5, putative 3926 14176 24426
Re02.g14800 Sin3 complex subunit 3927 14177 24427
Mitochondrial intermembrane
space translocase subunit Tim10,
Re02.g14810 putative 3928 14178 24428
Re02.g14820 Putative uncharacterized protein 3929 14179 24429
Re02.g14830 Uncharacterized protein 3930 14180 24430 31325 32815
Re02.g 14840 Putative uncharacterized protein 3931 14181 24431
Re02.g14850 Putative uncharacterized protein 3932 14182 24432
Peroxisomal ABC transporter
Re02.g14860 (PXA1), putative 3933 14183 24433
General stress response
phosphoprotein phosphatase
Re02.g14870 Psr1/2, putative 3934 14184 24434
Re02.g14880 Protein phosphatase 1 3935 14185 24435
Re02.g14890 Putative uncharacterized protein 3936 14186 24436 31326 32816 Re02.g14900 Putative uncharacterized protein 3937 14187 24437
Re02.g14910 Xylose reductase 3938 14188 24438
Re02.g14920 Uncharacterized protein 3939 14189 24439
Pre-rRNA processing protein Mrd1 ,
Re02.g14930 putative 3940 14190 24440
Re02.g 14940 Dynein light chain type 1 3941 14191 24441
Re02.g14950 Putative uncharacterized protein 3942 14192 24442
Re02.g14960 Urea transporter (Dur3), putative 3943 14193 24443
Translocon protein Sec61 beta,
Re02.g14970 putative 3944 14194 24444
Re02.g14980 Putative uncharacterized protein 3945 14195 24445
Re02.g14990 Proliferating cell nuclear antigen 3946 14196 24446
Re02.g15000 Calmodulin-binding protein Sha1 3947 14197 24447
Re02.g15010 MFS transporter, putative 3948 14198 24448
Re02.g 15020 Putative uncharacterized protein 3949 14199 24449
Re02.g15030 hypothetical protein 3950 14200 24450
Re02.g 15040 Putative uncharacterized protein 3951 14201 24451
Small monomeric GTPase SarA,
Re02.g 15050 putative 3952 14202 24452
Serine/threonine protein
Re02.g 15060 phosphatase PP1 , putative 3953 14203 24453
Re02.g15070 hypothetical protein 3954 14204 24454
Re02.g15080 Uncharacterized protein 3955 14205 24455
Re02.g15090 hypothetical protein 3956 14206 24456
Patatin-like phospholipase domain- containing protein NFIA 019760
Re02.g15100 EC=3.1.1.- 3957 14207 24457
RNA polymerase III transcription
factor TFIIIC subunit (Tfc4),
Re02.g151 10 putative 3958 14208 24458
Re02.g15120 hypothetical protein 3959 14209 24459
Re02.g15130 SAM domain protein 3960 14210 24460
Re02.g15140 Putative uncharacterized protein 3961 1421 1 24461
Re02.g15150 MFS multidrug transporter, putative 3962 14212 24462
Re02.g15160 hypothetical protein 3963 14213 24463 31327 32817
Re02.g15170 Uncharacterized protein 3964 14214 24464
Mitochondrial protein import protein
Re02.g15180 MAS5 , putative 3965 14215 24465
Re02.g15190 Cytosine deaminase 3966 14216 24466
Uroporphyrinogen decarboxylase
Re02.g 15200 EC=4.1.1.37 3967 14217 24467
Re02.g15210 tRNA methyltransferase, putative 3968 14218 24468
60S acidic ribosomal protein P0,
Re02.g 15220 putative 3969 14219 24469
GARP complex subunit Vps53,
Re02.g 15230 putative 3970 14220 24470
Re02.g 15240 mRNA export factor mex67 3971 14221 24471
COPII-coated vesicle membrane
Re02.g 15250 protein Erv46 3972 14222 24472 Re02.g 15260 PH domain protein 3973 14223 24473 31328 32818 tRNA splicing 2'
Re02.g 15270 phosphotransferase 1 3974 14224 24474
Re02.g 15280 hypothetical protein 3975 14225 24475
Re02.g 15290 Uncharacterized protein 3976 14226 24476
DNA-directed RNA polymerase I,
Re02.g15300 II, and III subunit Rpb6 3977 14227 24477
MFS monocarboxylate transporter,
Re02.g15310 putative 3978 14228 24478
N-acetyltransferase (Nat5),
Re02.g 15320 putative 3979 14229 24479
Re02.g15330 Putative uncharacterized protein 3980 14230 24480
Eukaryotic translation initiation
Re02.g 15340 factor 3 subunit A 3981 14231 24481
G-protein complex gamma subunit
Re02.g 15350 GpgA 3982 14232 24482
C6 and C2H2 transcription factor,
Re02.g 15360 putative 3983 14233 24483
Re02.g15370 Uncharacterized protein 3984 14234 24484
High affinity cAMP
Re02.g15380 phosphodiesterase, putative 3985 14235 24485
Re02.g15390 hypothetical protein 3986 14236 24486 31329 32819
Re02.g 15400 hypothetical protein 3987 14237 24487
Re02.g15410 Putative uncharacterized protein 3988 14238 24488
Re02.g 15420 hypothetical protein 3989 14239 24489
PHD finger and BAH domain
Re02.g 15430 protein (Snt2), putative 3990 14240 24490
Re02.g 15440 hypothetical protein 3991 14241 24491
Re02.g 15450 hypothetical protein 3992 14242 24492
DNA-directed DNA polymerase
Re02.g 15460 theta, putative 3993 14243 24493
Re02.g 15470 Similar to An01g04530 3994 14244 24494 31330 32820
Vacuolar assembly/sorting protein
Re02.g 15480 VPS8 3995 14245 24495
Re02.g 15490 Endo-1 ,3(4)-beta-glucanase 3996 14246 24496 31331 32821
Re02.g 15500 Capsular associated protein 3997 14247 24497
Re02.g15510 Nucleolar ATPase Kre33, putative 3998 14248 24498
Re02.g 15520 Disulfide isomerase, putative 3999 14249 24499 31332 32822
Re02.g 15530 F-box domain protein 4000 14250 24500
Re02.g 15540 Uncharacterized protein 4001 14251 24501
Re02.g 15550 ATP synthase subunit gamma 4002 14252 24502
Re02.g 15560 Topoisomerase I EC=1.3.1.74 4003 14253 24503
Epimerase/dehydratase family
Re02.g 15570 protein 4004 14254 24504 31333 32823
Re02.g 15580 Putative uncharacterized protein 4005 14255 24505
Re02.g 15590 Putative uncharacterized protein 4006 14256 24506
Re02.g 15600 Calpain-like protease PalBory 4007 14257 24507
Peroxisomal carrier protein,
Re02.g15610 putative 4008 14258 24508 31334 32824 Re02.g 15620 Uncharacterized protein 4009 14259 24509
Probable endonuclease Icl3
Re02.g 15630 EC=3.1.-.- 4010 14260 24510
Re02.g 15640 Adenylate kinase 2 4011 14261 24511
Re02.g 15650 DNA primase large subunit 4012 14262 24512
Protein transport protein Sec23,
Re02.g 15660 putative 4013 14263 24513
Re02.g 15670 60S ribosomal protein L12 4014 14264 24514
Re02.g 15680 Putative uncharacterized protein 4015 14265 24515
Re02.g 15690 hypothetical protein 4016 14266 24516
UDP-N-
Re02.g15700 acetylglucosaminyltransferase 4017 14267 24517
MYB family conidiophore
Re02.g15710 development protein FIbD, putative 4018 14268 24518
Re02.g 15720 hypothetical protein 4019 14269 24519 31335 32825
Re02.g15730 Predicted protein 4020 14270 24520
Re02.g 15740 Putative uncharacterized protein 4021 14271 24521
Re02.g 15750 Putative uncharacterized protein 4022 14272 24522
Putative uncharacterized protein
Re02.g 15760 An01g04930 EC=3.6.3.14 4023 14273 24523
Re02.g15770 Putative uncharacterized protein 4024 14274 24524
Re02.g15780 Uncharacterized protein 4025 14275 24525
Re02.g15790 Putative uncharacterized protein 4026 14276 24526
Re02.g15800 C2H2 transcription factor, putative 4027 14277 24527
Re02.g15810 Putative uncharacterized protein 4028 14278 24528
Re02.g 15820 Uncharacterized protein 4029 14279 24529
Phosphotransferase enzyme family
Re02.g15830 domain protein 4030 14280 24530
Re02.g 15840 Putative uncharacterized protein 4031 14281 24531
Re02.g 15850 Alpha/beta-Hydrolase 4032 14282 24532
Re02.g 15860 DUTPase (Dut), putative 4033 14283 24533
Re02.g15870 Pyridoxine kinase 4034 14284 24534
Re02.g15880 C6 transcription factor, putative 4035 14285 24535
Re02.g15890 Putative uncharacterized protein 4036 14286 24536 31336 32826
Re02.g15900 Putative uncharacterized protein 4037 14287 24537
Re02.g15910 Calmodulin, putative 4038 14288 24538
Mitotic check point protein (Bub2),
Re02.g 15920 putative 4039 14289 24539
Re02.g15930 Putative uncharacterized protein 4040 14290 24540
Re02.g 15940 WD repeat-containing protein 4041 14291 24541
Re02.g 15950 Uncharacterized protein 4042 14292 24542
6-phosphogluconolactonase,
Re02.g 15960 putative 4043 14293 24543
Re02.g15970 Putative uncharacterized protein 4044 14294 24544
Re02.g15980 hypothetical protein 4045 14295 24545
Re02.g15990 RNA binding protein 4046 14296 24546
Cell cycle control protein (Cwf22),
Re02.g16000 putative 4047 14297 24547
Re02.g16010 Uncharacterized protein 4048 14298 24548 31337 32827 Re02.g16020 Uncharacterized protein 4049 14299 24549
Re02.g16030 Uncharacterized protein 4050 14300 24550
Re02.g 16040 Uncharacterized protein 4051 14301 24551 31338 32828
Re02.g16050 Helicase, putative 4052 14302 24552 31339 32829
F-actin capping protein beta
Re02.g16060 subunit 4053 14303 24553
Re02.g16070 Uncharacterized protein 4054 14304 24554
Transcription initiation factor TFIID
Re02.g16080 subunit, putative 4055 14305 24555
Re02.g16090 Uncharacterized protein 4056 14306 24556
Carboxylesterase-mitochondrial
Re02.g16100 37S ribosomal protein YmS2 4057 14307 24557
Re02.g161 10 Integral membrane protein 4058 14308 24558
Endoplasmic reticulum and nuclear
Re02.g16120 membrane proteinc Npl4, putative 4059 14309 24559
NADH-quinone oxidoreductase,
Re02.g16130 putative 4060 14310 24560 31340 32830
Re02.g16140 Uncharacterized protein Fragment 4061 1431 1 24561
Re02.g16150 Class V chitinase, putative 4062 14312 24562
Re02.g16160 Putative uncharacterized protein 4063 14313 24563
Re02.g16170 Uncharacterized protein 4064 14314 24564 31341 32831
Re02.g16180 Class V chitinase, putative 4065 14315 24565
Ankyrin repeat-containing protein,
Re02.g16190 putative 4066 14316 24566
Re02.g16200 Uncharacterized protein 4067 14317 24567
Re02.g16210 hypothetical protein 4068 14318 24568
Re02.g 16220 hypothetical protein 4069 14319 24569
Re02.g16230 Predicted protein 4070 14320 24570
Re02.g 16240 hypothetical protein 4071 14321 24571
Re02.g 16250 Putative uncharacterized protein 4072 14322 24572
Putative uncharacterized protein
Re02.g 16260 An08g03720 4073 14323 24573
Re02.g16270 hypothetical protein 4074 14324 24574
Re02.g16280 Uncharacterized protein 4075 14325 24575
Fatty-acid amide hydrolase,
Re02.g16290 putative 4076 14326 24576
Re02.g16300 Zinc metallopeptidase, putative 4077 14327 24577
Re02.g16310 Uncharacterized protein 4078 14328 24578
Re02.g16320 Predicted protein 4079 14329 24579
NAD dependent
Re02.g16330 epimerase/dehydratase, putative 4080 14330 24580
Re02.g 16340 Putative uncharacterized protein 4081 14331 24581
ARP2/3 complex 34 kDa subunit ,
Re02.g16350 putative 4082 14332 24582
Re02.g16360 WD domain protein 4083 14333 24583
Re02.g16370 F-box domain protein 4084 14334 24584 31342 32832
Re02.g16380 Putative uncharacterized protein 4085 14335 24585
Re02.g16390 Putative uncharacterized protein 4086 14336 24586 31343 32833
Re02.g 16400 RRNA processing protein, putative 4087 14337 24587 Re02.g16410 Putative uncharacterized protein 4088 14338 24588
rRNA processing protein Pwp1 ,
Re02.g 16420 putative 4089 14339 24589
Re02.g 16430 Uncharacterized protein 4090 14340 24590
Re02.g 16440 Predicted protein 4091 14341 24591
Re02.g 16450 hypothetical protein 4092 14342 24592
Re02.g 16460 Putative uncharacterized protein 4093 14343 24593
RNA polymerase I specific
transcription initiation factor RRN3
Re02.g 16470 superfamily 4094 14344 24594
Re02.g 16480 Lipase, putative 4095 14345 24595 31344 32834
Aspartyl-tRNA synthetase,
Re02.g 16490 cytoplasmic 4096 14346 24596
Re02.g16500 Putative uncharacterized protein 4097 14347 24597
Re02.g16510 Predicted protein 4098 14348 24598
Re02.g 16520 UDP-glucose,sterol transferase 4099 14349 24599
Re02.g16530 RTA1 domain protein, putative 4100 14350 24600
Re02.g 16540 Uncharacterized protein 4101 14351 24601
Re02.g 16550 Heat shock protein 90 4102 14352 24602
Re02.g 16560 Uncharacterized protein 4103 14353 24603
HLH transcription factor (PalcA),
Re02.g16570 putative 4104 14354 24604
Synaptic vesicle transporter SVOP
Re02.g16580 and related transporters 4105 14355 24605
Re02.g16590 hypothetical protein 4106 14356 24606
Re02.g16600 Uncharacterized protein 4107 14357 24607
NAD-binding Rossmann fold
Re02.g16610 oxidoreductase family protein 4108 14358 24608
Putative uncharacterized protein
Re02.g 16620 Fragment 4109 14359 24609
Re02.g16630 NTF2 and RRM domain protein 4110 14360 24610
Re02.g 16640 Similar to An09g06570 4111 14361 24611
Re02.g 16650 Putative uncharacterized protein 4112 14362 24612
MIND kinetochore complex
Re02.g 16660 component Nn l 4113 14363 24613
Re02.g16670 Uncharacterized protein 4114 14364 24614
Cyclin-dependent protein kinase
Re02.g16680 PhoA EC=2.7.11.23 4115 14365 24615
SIR2 family histone deacetylase,
Re02.g16690 putative 4116 14366 24616 31345 32835
Cation efflux family protein,
Re02.g16700 putative 4117 14367 24617
Re02.g16710 Xylulokinase 4118 14368 24618
Re02.g16720 tRNA exportin, putative 4119 14369 24619
Putative uncharacterized protein
Re02.g16730 An07g03100 EC=3.1.1.1 4120 14370 24620
Re02.g 16740 Separin 4121 14371 24621
Putative uncharacterized protein
Re02.g16750 Precursor 4122 14372 24622 Mitochondrial carrier protein,
Re02.g16760 putative 4123 14373 24623
Re02.g16770 DNA N-glycosylase 4124 14374 24624
Re02.g16780 Splicing factor u2af large subunit 4125 14375 24625
Re02.g16790 Uncharacterized protein 4126 14376 24626
Re02.g16800 Monooxygenase, putative 4127 14377 24627
Nitrogen assimilation transcription
Re02.g16810 factor nit-4, putative 4128 14378 24628
Re02.g16820 Uncharacterized protein 4129 14379 24629
Re02.g16830 40S ribosomal protein S13 4130 14380 24630
Re02.g 16840 Uncharacterized protein 4131 14381 24631
Re02.g16850 Putative uncharacterized protein 4132 14382 24632
Re02.g16860 Uncharacterized protein 4133 14383 24633
Re02.g16870 Pc06g02290 protein Precursor 4134 14384 24634
COMPASS complex subunit Sdd ,
Re02.g16880 putative 4135 14385 24635
Transformer-SR ribonudeoprotein,
Re02.g16890 variant 4136 14386 24636
PHD finger domain protein,
Re02.g16900 putative 4137 14387 24637
Re02.g16910 Predicted protein 4138 14388 24638
Re02.g16920 Putative uncharacterized protein 4139 14389 24639
Re02.g16930 Glycoprotease family protein 4140 14390 24640 31346 32836
Re02.g 16940 Ankyrin repeat-containing protein 4141 14391 24641
Re02.g16950 Uncharacterized protein 4142 14392 24642
Re02.g16960 Putative uncharacterized protein 4143 14393 24643 31347 32837
Re02.g16970 Uncharacterized protein 4144 14394 24644
Re02.g16980 Uncharacterized protein 4145 14395 24645
Re02.g16990 Zn(ll)2Cys6 transcription factor 4146 14396 24646
Cellular morphogenesis protein
Re02.g17000 (Rax2), putative 4147 14397 24647 31348 32838
Re02.g17010 hypothetical protein 4148 14398 24648
Re02.g17020 FACT complex subunit pob3 4149 14399 24649
Re02.g17030 Similar to Pc21g09640 4150 14400 24650
Re02.g 17040 Putative uncharacterized protein 4151 14401 24651
Re02.g17050 hypothetical protein 4152 14402 24652 31349 32839
Re02.g17060 Putative uncharacterized protein 4153 14403 24653
Re02.g17070 SAP domain protein, putative 4154 14404 24654
Re02.g17080 Putative uncharacterized protein 4155 14405 24655
Re02.g17090 Putative uncharacterized protein 4156 14406 24656
Re02.g17100 Predicted protein 4157 14407 24657
Re02.g17110 Predicted protein 4158 14408 24658
Re02.g17120 Uncharacterized protein 4159 14409 24659
Malate/L-lactate dehydrogenase,
Re02.g17130 putative 4160 14410 24660
Re02.g17140 Putative uncharacterized protein 4161 14411 24661 31350 32840
Splicing factor 3B subunit 1 ,
Re02.g17150 putative 4162 14412 24662
Re02.g17160 Predicted protein 4163 14413 24663 Putative fumarate reductase
Re02.g17170 flavoprotein subunit protein 4164 14414 24664
Re02.g17180 hypothetical protein 4165 14415 24665
C2H2 conidiation transcription
Re02.g17190 factor FlbC 4166 14416 24666
Function: Tto1 can transpose
autonomously through reverse
transcription EC=2.7.7.49
EC=2.7.7.49 EC=2.7.7.49
Re02.g17200 EC=2.7.7.49 4167 14417 24667
Re02.g17210 hypothetical protein 4168 14418 24668
Re02.g 17220 Putative uncharacterized protein 4169 14419 24669
Re02.g17230 Uncharacterized protein 4170 14420 24670
Re02.g 17240 Uncharacterized protein 4171 14421 24671
Re02.g 17250 Uncharacterized protein 4172 14422 24672
Putative uncharacterized protein
Re02.g 17260 An03g01010 Precursor 4173 14423 24673 31351 32841
UV-damaged DNA binding protein,
Re02.g17270 putative 4174 14424 24674
Re02.g17280 Nonribosomal peptide synthase 4175 14425 24675
Re02.g17290 Putative uncharacterized protein 4176 14426 24676
3-hydroxyisobutyrate
Re02.g17300 dehydrogenase 4177 14427 24677
Cell morphogenesis protein
Re02.g17310 (PAG1), putative 4178 14428 24678
NADPH-cytochrome P450
Re02.g17320 reductase EC=1.6.2.4 4179 14429 24679 31352 32842
Re02.g17330 RNA binding protein MSSP-2 4180 14430 24680
Re02.g 17340 FAD synthetase, putative 4181 14431 24681
Re02.g17350 DnaJ domain protein 4182 14432 24682
ATP-dependent RNA helicase
Re02.g17360 DBP4 4183 14433 24683
Re02.g17370 Uncharacterized protein 4184 14434 24684
Re02.g17380 Amino acid permease, putative 4185 14435 24685
Re02.g17390 C6 transcription factor, putative 4186 14436 24686
Re02.g 17400 Putative uncharacterized protein 4187 14437 24687
MATE efflux family protein
Re02.g17410 subfamily, putative 4188 14438 24688
Re02.g 17420 Possible replication factor-a protein 4189 14439 24689
Dead box ATP-dependent ma
Re02.g 17430 helicase 4190 14440 24690
Re02.g 17440 Pc21g21730 protein 4191 14441 24691
Re02.g 17450 Predicted protein 4192 14442 24692
Re02.g 17460 Putative uncharacterized protein 4193 14443 24693
Re02.g 17470 Protein kinase (VPS15), putative 4194 14444 24694
Re02.g 17480 Ser/Thr protein phosphatase 4195 14445 24695
Re02.g 17490 Uncharacterized protein 4196 14446 24696
Re02.g17500 Putative uncharacterized protein 4197 14447 24697
Re02.g17510 hypothetical protein 4198 14448 24698 Re02.g 17520 hypothetical protein 4199 14449 24699
Re02.g17530 hypothetical protein 4200 14450 24700
Re02.g 17540 Uncharacterized protein 4201 14451 24701
Re02.g 17550 hypothetical protein 4202 14452 24702
Re02.g 17560 hypothetical protein 4203 14453 24703
Re02.g17570 DENN domain-containing protein 4204 14454 24704
Re02.g17580 BTB/POZ domain protein 4205 14455 24705
3-oxoacyl-(Acyl-carrier-protein)
Re02.g17590 reductase 4206 14456 24706
Re02.g17600 TBC domain protein, putative 4207 14457 24707
Re02.g17610 Putative uncharacterized protein 4208 14458 24708 31353 32843
Re02.g 17620 Ribosomal protein L26 4209 14459 24709
C2H2 finger domain protein,
Re02.g17630 putative 4210 14460 24710
Re02.g 17640 Putative uncharacterized protein 421 1 14461 2471 1
Re02.g 17650 C6 transcription factor, putative 4212 14462 24712
Re02.g 17660 Putative uncharacterized protein 4213 14463 24713
Re02.g17670 hypothetical protein 4214 14464 24714
Re02.g17680 Putative uncharacterized protein 4215 14465 24715
Re02.g17690 hypothetical protein 4216 14466 24716
Integral membrane channel
Re02.g17700 protein, putative 4217 14467 24717
Re02.g17710 Aspartate carbamoyltransferase 4218 14468 24718
Re02.g17720 Putative uncharacterized protein 4219 14469 24719
Re02.g17730 Putative uncharacterized protein 4220 14470 24720 31354 32844
Re02.g 17740 Uncharacterized protein 4221 14471 24721
Re02.g17750 Uncharacterized protein 4222 14472 24722
Exocyst complex component
Re02.g17760 Exo84, putative 4223 14473 24723
Mitochondrial import receptor
Re02.g17770 subunit (Tom20), putative 4224 14474 24724 31355 32845
Cytosolic phospholipase A2,
Re02.g17790 putative 4225 14475 24725
Re02.g17800 Uncharacterized protein 4226 14476 24726
Re02.g17810 Putative uncharacterized protein 4227 14477 24727
Re02.g17820 hypothetical protein 4228 14478 24728
Re02.g17830 Cytochrome P450 monooxygenase 4229 14479 24729
Re02.g 17840 Reverse transcriptase, putative 4230 14480 24730
Re02.g17850 Uncharacterized protein 4231 14481 24731
Flavodoxin and radical SAM
Re02.g17860 domain protein 4232 14482 24732 31356 32846
Re02.g17870 Uncharacterized protein 4233 14483 24733
Re02.g17880 Uncharacterized protein 4234 14484 24734
Re02.g17890 NUDIX domain protein 4235 14485 24735
TOR signaling pathway
Re02.g17900 phosphatase SitA 4236 14486 24736
Nonsense-mediated mRNA decay
Re02.g17910 protein Upf3, putative 4237 14487 24737
Re02.g17920 Aldehyde dehydrogenase, putative 4238 14488 24738 EC=1.2.1.3
Double-strand break repair protein
Re02.g17930 mus-23 4239 14489 24739
Re02.g 17940 F-box and WD domain protein 4240 14490 24740
Re02.g17950 Uncharacterized protein 4241 14491 24741
Re02.g17960 Signal peptidase I 4242 14492 24742 31357 32847
Re02.g17970 Uncharacterized protein 4243 14493 24743
Re02.g17980 hypothetical protein 4244 14494 24744 31358 32848
Re02.g17990 hypothetical protein 4245 14495 24745 31359 32849
Re02.g18000 Putative uncharacterized protein 4246 14496 24746 31360 32850
Histidine acid phosphatase,
Re02.g18010 putative 4247 14497 24747 31361 32851
TAM domain methyltransferase,
Re02.g18020 putative 4248 14498 24748
Re02.g18030 Amino acid transporter, putative 4249 14499 24749
Putative short chain
Re02.g 18040 dehydrogenase protein 4250 14500 24750
Re02.g18050 Uncharacterized protein 4251 14501 24751
Re02.g18060 General amidase, partial 4252 14502 24752
Re02.g18070 Uncharacterized protein 4253 14503 24753 31362 32852
Re02.g18080 Uncharacterized protein 4254 14504 24754
Endonuclease/reverse
Re02.g18090 transcriptase, putative 4255 14505 24755
Re03.g00010 hypothetical protein 4256 14506 24756
Re03.g00020 hypothetical protein 4257 14507 24757
Re03.g00030 Putative uncharacterized protein 4258 14508 24758
Re03.g00040 Uncharacterized protein Fragment 4259 14509 24759
Transposon-encoded proteins with
Re03.g00050 TYA 4260 14510 24760
Re03.g00060 hypothetical protein 4261 1451 1 24761
Re03.g00070 hypothetical protein 4262 14512 24762
Re03.g00080 Putative uncharacterized protein 4263 14513 24763
Re03.g00090 Uncharacterized protein 4264 14514 24764
Re03.g00100 Putative uncharacterized protein 4265 14515 24765
Re03.g001 10 Putative uncharacterized protein 4266 14516 24766
Re03.g00120 Uncharacterized protein 4267 14517 24767
Re03.g00130 hypothetical protein 4268 14518 24768 31363 32853
Putative uncharacterized protein
Re03.g00140 Fragment 4269 14519 24769
Re03.g00150 hypothetical protein 4270 14520 24770
Vegetative incompatibility WD
Re03.g00160 repeat protein, putative 4271 14521 24771
Re03.g00170 Uncharacterized protein 4272 14522 24772
Re03.g00180 Transposon, putative 4273 14523 24773
Re03.g00190 Putative uncharacterized protein 4274 14524 24774
Re03.g00200 Predicted protein 4275 14525 24775 31364 32854
Re03.g00210 hypothetical protein 4276 14526 24776
Re03.g00220 hypothetical protein 4277 14527 24777
Re03.g00230 Uncharacterized protein 4278 14528 24778 31365 32855 Re03.g00240 hypothetical protein 4279 14529 24779
Pogo transposable element,
Re03.g00250 putative 4280 14530 24780
Re03.g00260 hypothetical protein 4281 14531 24781
Re03.g00270 hypothetical protein 4282 14532 24782
Re03.g00280 Putative uncharacterized protein 4283 14533 24783
Re03.g00290 Uncharacterized protein 4284 14534 24784
Re03.g00300 Putative uncharacterized protein 4285 14535 24785 31366 32856
Re03.g00310 Mucin-1 , putative 4286 14536 24786
Re03.g00320 Predicted protein 4287 14537 24787 31367 32857
Re03.g00330 hypothetical protein 4288 14538 24788
Re03.g00340 Putative uncharacterized protein 4289 14539 24789
2-(R)-hydroxypropyl-CoM
Re03.g00350 dehydrogenase 4290 14540 24790 31368 32858
Re03.g00360 Uncharacterized protein 4291 14541 24791
MFS allantoate transporter,
Re03.g00370 putative 4292 14542 24792
Re03.g00380 Amino acid permease, putative 4293 14543 24793
Re03.g00390 Putative uncharacterized protein 4294 14544 24794
Re03.g00400 Alcohol dehydrogenase, putative 4295 14545 24795
Re03.g00410 Uncharacterized protein 4296 14546 24796 31369 32859
Peptidyl-prolyl cis-trans isomerase,
Re03.g00420 putative 4297 14547 24797
Re03.g00430 T-complex protein 1 4298 14548 24798
Re03.g00440 Glycosyl hydrolase, putative 4299 14549 24799 31370 32860
Protein kinase and ribonuclease
Re03.g00450 Ire1 , putative 4300 14550 24800 31371 32861
Re03.g00460 Uncharacterized protein 4301 14551 24801
Re03.g00470 Conserved serine-rich protein 4302 14552 24802
Branched-chain amino acid
Re03.g00480 aminotransferase 4303 14553 24803
Puromycin resistance protein pur8,
Re03.g00490 putative 4304 14554 24804
Formaldehyde dehydrogenase,
Re03.g00500 putative 4305 14555 24805
Putative allantoate permease of the
Re03.g00510 major facilitator superfamily 4306 14556 24806
Re03.g00520 hypothetical protein 4307 14557 24807
K homeostasis protein Kha1 ,
Re03.g00530 putative 4308 14558 24808
Re03.g00540 hypothetical protein 4309 14559 24809
Re03.g00550 hypothetical protein 4310 14560 24810
Re03.g00560 Uncharacterized protein 431 1 14561 2481 1
Re03.g00570 Putative uncharacterized protein 4312 14562 24812
Re03.g00580 Putative uncharacterized protein 4313 14563 24813
Re03.g00590 Putative uncharacterized protein 4314 14564 24814 31372 32862
Re03.g00600 hypothetical protein 4315 14565 24815
Re03.g00610 Monooxygenase, putative 4316 14566 24816
Re03.g00620 hypothetical protein 4317 14567 24817 31373 32863 Cell surface spherulin 4-like
Re03.g00630 protein, putative 4318 14568 24818 31374 32864
Re03.g00640 Thioredoxin II, putative 4319 14569 24819
Re03.g00650 Uncharacterized protein 4320 14570 24820
Re03.g00660 Pc22g22430 protein Precursor 4321 14571 24821
Re03.g00670 MFS transporter 4322 14572 24822
Re03.g00680 hypothetical protein 4323 14573 24823
Re03.g00690 Uncharacterized protein 4324 14574 24824
Re03.g00700 Cysteine desulfurylase, putative 4325 14575 24825
Re03.g00710 hypothetical protein 4326 14576 24826
Re03.g00720 Uncharacterized protein 4327 14577 24827
Re03.g00730 Putative uncharacterized protein 4328 14578 24828
Integral membrane protein,
Re03.g00740 putative 4329 14579 24829
Re03.g00750 C6 finger domain protein, putative 4330 14580 24830
Re03.g00760 Putative uncharacterized protein 4331 14581 24831
Re03.g00770 hypothetical protein 4332 14582 24832
Re03.g00780 Putative uncharacterized protein 4333 14583 24833
Re03.g00790 hypothetical protein 4334 14584 24834
Re03.g00800 VeA-like protein 4335 14585 24835
Re03.g00810 Uncharacterized protein 4336 14586 24836
Re03.g00820 Putative uncharacterized protein 4337 14587 24837
Re03.g00830 Protein kinase 4338 14588 24838 31375 32865
Re03.g00840 Putative uncharacterized protein 4339 14589 24839
MYB DNA-binding domain-
Re03.g00850 containing protein 4340 14590 24840
Re03.g00860 C2H2 finger domain protein 4341 14591 24841
Re03.g00870 Putative uncharacterized protein 4342 14592 24842
Re03.g00880 Putative uncharacterized protein 4343 14593 24843
Re03.g00890 hypothetical protein 4344 14594 24844 31376 32866
Re03.g00900 hypothetical protein 4345 14595 24845
Re03.g00910 Uncharacterized protein 4346 14596 24846
Re03.g00920 hypothetical protein 4347 14597 24847
Re03.g00930 hypothetical protein 4348 14598 24848
Re03.g00940 Pc17g00310 protein 4349 14599 24849
Re03.g00950 Uncharacterized protein 4350 14600 24850
Re03.g00960 Putative uncharacterized protein 4351 14601 24851
Re03.g00970 hypothetical protein 4352 14602 24852 31377 32867
Eukaryotic translation initiation
Re03.g00980 factor 3 subunit B 4353 14603 24853
Re03.g00990 SWIB/MDM2 domain protein 4354 14604 24854
C2H2 finger domain protein,
Re03.g01000 putative 4355 14605 24855
Re03.g01010 DNA mismatch repair protein 4356 14606 24856
Re03.g01020 WD repeat protein 4357 14607 24857
Re03.g01030 Uncharacterized protein 4358 14608 24858
Re03.g01040 hypothetical protein 4359 14609 24859
Secretion pathway protein
Re03.g01050 Sls2/Rcy1 , putative 4360 14610 24860 Re03.g01060 Cytochrome C1/Cyt1 , putative 4361 1461 1 24861
Re03.g01070 Uncharacterized protein 4362 14612 24862
Re03.g01080 hypothetical protein 4363 14613 24863
Phospho-2-dehydro-3- deoxyheptonate aldolase
Re03.g01090 EC=2.5.1.54 4364 14614 24864
Re03.g01 100 F-box domain protein 4365 14615 24865
Re03.g01 1 10 Pc22g 19300 protein 4366 14616 24866 31378 32868
Re03.g01 120 Putative uncharacterized protein 4367 14617 24867
Re03.g01 130 Putative uncharacterized protein 4368 14618 24868
Re03.g01 140 DUF221 domain protein, putative 4369 14619 24869 31379 32869
Glycogen debranching enzyme
Re03.g01 150 Gdb1 , putative 4370 14620 24870
Glycerol 3-phosphate
Re03.g01 160 dehydrogenase (GfdA), putative 4371 14621 24871
Re03.g01 170 Putative uncharacterized protein 4372 14622 24872
Re03.g01 180 Putative uncharacterized protein 4373 14623 24873
Molybdenum cofactor biosynthetic
Re03.g01 190 protein (CnxF), putative 4374 14624 24874
Re03.g01200 Uncharacterized protein 4375 14625 24875
Re03.g01210 Putative uncharacterized protein 4376 14626 24876
Iron-sulfur protein subunit of
succinate dehydrogenase Sdh2,
Re03.g01220 putative EC=1.3.5.1 4377 14627 24877 31380 32870
Re03.g01230 Pol Fragment 4378 14628 24878
Fructose-bisphosphate aldolase,
Re03.g01240 putative 4379 14629 24879
Re03.g01250 Oxidoreductase, putative 4380 14630 24880 31381 32871
Re03.g01260 hypothetical protein 4381 14631 24881
Re03.g01270 hypothetical protein 4382 14632 24882
Re03.g01280 hypothetical protein 4383 14633 24883
Re03.g01290 hypothetical protein 4384 14634 24884
Re03.g01300 hypothetical protein 4385 14635 24885
Re03.g01310 Putative uncharacterized protein 4386 14636 24886
Re03.g01320 Putative uncharacterized protein 4387 14637 24887
Re03.g01330 Alanyl-tRNA synthetase, putative 4388 14638 24888 31382 32872
Re03.g01340 hypothetical protein 4389 14639 24889
Re03.g01350 hypothetical protein 4390 14640 24890
Re03.g01360 Putative uncharacterized protein 4391 14641 24891
Re03.g01370 hypothetical protein 4392 14642 24892 31383 32873
Re03.g01380 Carboxylesterase, putative 4393 14643 24893
Re03.g01390 Predicted protein 4394 14644 24894
Re03.g01400 Uncharacterized protein 4395 14645 24895
5-Methylcytosine G/T mismatch-
Re03.g01410 specific DNA glycosylase, putative 4396 14646 24896
Remark: protein of the patent is
useful useful for diagnosis or
Re03.g01420 vaccine production 4397 14647 24897
Re03.g01430 Gamma-glutamyltranspeptidase 4398 14648 24898 Re03.g01440 Putative uncharacterized protein 4399 14649 24899
Re03.g01450 Uncharacterized protein 4400 14650 24900
Re03.g01460 Putative uncharacterized protein 4401 14651 24901 31384 32874
Re03.g01470 hypothetical protein 4402 14652 24902 31385 32875
Re03.g01480 Uncharacterized protein 4403 14653 24903
Re03.g01490 Putative pantothenate protein 4404 14654 24904
Re03.g01500 Uncharacterized protein 4405 14655 24905
Re03.g01510 Asparagine synthetase EC=6.3.5.4 4406 14656 24906
Re03.g01520 Uncharacterized protein 4407 14657 24907 31386 32876
Re03.g01530 hypothetical protein 4408 14658 24908
Argininosuccinate synthase
Re03.g01540 EC=6.3.4.5 4409 14659 24909
Re03.g01550 Uncharacterized protein 4410 14660 24910
Re03.g01560 60S ribosomal protein L3 441 1 14661 2491 1
Re03.g01570 Putative uncharacterized protein 4412 14662 24912
Transcriptional corepressor Cyc8,
Re03.g01580 putative 4413 14663 24913
Putative short-chain
dehydrogenase reductase family
Re03.g01590 protein 4414 14664 24914
Re03.g01600 hypothetical protein 4415 14665 24915
Re03.g01610 Uncharacterized protein 4416 14666 24916
Re03.g01620 hypothetical protein 4417 14667 24917
Pre-rRNA processing protein
Re03.g01630 Rrp12, putative 4418 14668 24918
Re03.g01640 hypothetical protein 4419 14669 24919
Re03.g01650 Uncharacterized protein Fragment 4420 14670 24920
Re03.g01660 Uncharacterized protein Fragment 4421 14671 24921
Re03.g01670 Putative uncharacterized protein 4422 14672 24922
Re03.g01680 RNA helicase/RNAse III, putative 4423 14673 24923
Proteasome subunit alpha type
Re03.g01690 EC=3.4.25.1 4424 14674 24924
Re03.g01700 RING finger domain protein 4425 14675 24925
Exocyst complex component
Re03.g01710 Exo70, putative 4426 14676 24926
Re03.g01720 Phospholipase A2 (PlaA), putative 4427 14677 24927 31387 32877
Phosphoinositide phosphatase
Re03.g01730 Pten/Tep1 , putative EC=3.1.3.48 4428 14678 24928
Re03.g01740 Pentatricopeptide repeat protein 4429 14679 24929
Re03.g01750 Uncharacterized protein 4430 14680 24930 31388 32878
Histone acetyltransferase type B
Re03.g01760 catalytic subunit 4431 14681 24931
Re03.g01770 ZIP metal ion transporter, putative 4432 14682 24932 31389 32879
F-box and WD repeat-containing
Re03.g01780 protein 4433 14683 24933
Re03.g01790 C6 transcription factor, putative 4434 14684 24934
Re03.g01800 hypothetical protein 4435 14685 24935
Mitochondrial phosphate
Re03.g01810 transporter Pic2, putative 4436 14686 24936 Re03.g01820 Uncharacterized protein 4437 14687 24937
Re03.g01830 YagE family protein 4438 14688 24938
Re03.g01840 Immediate-early protein, putative 4439 14689 24939
Re03.g01850 Putative uncharacterized protein 4440 14690 24940
Pyrrol ine-5-carboxylate reductase
Re03.g01860 EC=1.5.1.2 4441 14691 24941
Voltage-gated chloride channel,
Re03.g01870 putative 4442 14692 24942
Re03.g01880 Midasin 4443 14693 24943
Re03.g01890 Putative uncharacterized protein 4444 14694 24944
Re03.g01900 Putative uncharacterized protein 4445 14695 24945
Lectin family integral membrane
Re03.g01910 protein, putative 4446 14696 24946 31390 32880
Re03.g01920 Uncharacterized protein 4447 14697 24947
cAMP-dependent protein kinase
Re03.g01930 type 2 4448 14698 24948
Stress activated MAP kinase
Re03.g01940 interacting protein, putative 4449 14699 24949
Putative uncharacterized protein
Re03.g01950 An02g04290 4450 14700 24950
Mitochondrial large ribosomal
Re03.g01960 subunit protein L16, putative 4451 14701 24951
DNA replication factor C subunit
Re03.g01970 Rfc5, putative 4452 14702 24952
Cytochrome c oxidase assembly
Re03.g01980 protein Cox1 1 , putative 4453 14703 24953
Re03.g01990 Integral membrane protein 4454 14704 24954
Re03.g02000 Uncharacterized protein 4455 14705 24955
Re03.g02010 Uncharacterized protein 4456 14706 24956
Re03.g02020 Uncharacterized protein 4457 14707 24957
Re03.g02030 Uncharacterized protein 4458 14708 24958
Re03.g02040 WD repeat protein 4459 14709 24959
Glucan endo-1 ,3-alpha-
Re03.g02050 glucosidase agnl , putative 4460 14710 24960 31391 32881
Glycoside hydrolase family 30
Re03.g02060 protein 4461 1471 1 24961 31392 32882
Re03.g02070 Predicted protein 4462 14712 24962
Required for respiratory growth
Re03.g02080 protein 9, mitochondrial Precursor 4463 14713 24963
Intracellular protein transport
Re03.g02090 protein 4464 14714 24964
Re03.g02100 Protein kinase regulator 4465 14715 24965
Re03.g021 10 Putative uncharacterized protein 4466 14716 24966
Re03.g02120 ATP synthase subunit 5 4467 14717 24967
Re03.g02130 Putative uncharacterized protein 4468 14718 24968
Re03.g02140 Putative uncharacterized protein 4469 14719 24969
Re03.g02150 hypothetical protein 4470 14720 24970
Re03.g02160 Putative uncharacterized protein 4471 14721 24971 31393 32883
Re03.g02170 Diphthamide biosynthesis protein 1 4472 14722 24972 Re03.g02180 Hydroxymethylglutaryl-CoA lyase 4473 14723 24973
Protein FMP21 , mitochondrial,
Re03.g02190 putative 4474 14724 24974
Acetylornithine aminotransferase,
Re03.g02200 mitochondrial 4475 14725 24975
Re03.g02210 Uncharacterized protein 4476 14726 24976
Re03.g02220 Protein btnl 4477 14727 24977
Re03.g02230 hypothetical protein 4478 14728 24978
Re03.g02240 Uncharacterized protein 4479 14729 24979
Re03.g02250 hypothetical protein 4480 14730 24980
Re03.g02260 Putative uncharacterized protein 4481 14731 24981
Carnitine acetyl transferase
Re03.g02270 EC=2.3.1.7 4482 14732 24982 31394 32884
Re03.g02280 hypothetical protein 4483 14733 24983
Re03.g02290 Transposase 4484 14734 24984
Re03.g02300 Uncharacterized protein 4485 14735 24985
Re03.g02310 hypothetical protein 4486 14736 24986
Re03.g02320 Putative uncharacterized protein 4487 14737 24987
12-oxophytodienoate reductase,
Re03.g02330 putative EC=1.3.1.42 4488 14738 24988
Re03.g02340 Uncharacterized protein Fragment 4489 14739 24989
Re03.g02350 MFS transporter, putative 4490 14740 24990
Re03.g02360 Uncharacterized protein 4491 14741 24991
Re03.g02370 Putative uncharacterized protein 4492 14742 24992 31395 32885
Re03.g02380 Thiolase-like protein 4493 14743 24993
Re03.g02390 Major facilitator superfamily 4494 14744 24994
Re03.g02400 Uncharacterized protein 4495 14745 24995
Re03.g02410 Uncharacterized protein 4496 14746 24996
Extracellular cell wall glucanase
Re03.g02420 Crfl /allergen Asp F9 4497 14747 24997 31396 32886
Calcium-independent
Re03.g02430 phospholipase A2-gamma 4498 14748 24998
Re03.g02440 Putative uncharacterized protein 4499 14749 24999
Re03.g02450 Putative uncharacterized protein 4500 14750 25000
Re03.g02460 Predicted protein Fragment 4501 14751 25001
Re03.g02470 Uncharacterized protein 4502 14752 25002
Re03.g02480 Uncharacterized protein 4503 14753 25003
Re03.g02490 Monooxygenase, putative 4504 14754 25004
Re03.g02500 Uncharacterized protein 4505 14755 25005 31397 32887
Re03.g02510 Uncharacterized protein 4506 14756 25006
Re03.g02520 Putative uncharacterized protein 4507 14757 25007
Re03.g02530 Uncharacterized protein 4508 14758 25008
Re03.g02540 Uncharacterized protein 4509 14759 25009
Re03.g02550 Predicted protein 4510 14760 25010
Re03.g02560 Uncharacterized protein 451 1 14761 2501 1
Re03.g02570 Putative uncharacterized protein 4512 14762 25012
Re03.g02580 Threonyl-tRNA synthetase 4513 14763 25013
Re03.g02590 Uncharacterized protein 4514 14764 25014
Re03.g02600 MFS quinate transporter 4515 14765 25015 Re03.g02610 Uncharacterized protein Fragment 4516 14766 25016
Re03.g02620 Uncharacterized protein 4517 14767 25017
Re03.g02630 hypothetical protein 4518 14768 25018 31398 32888
L-arabinitol 4-dehydrogenase
Re03.g02640 EC=1.1.1.12 4519 14769 25019
Re03.g02650 hypothetical protein 4520 14770 25020
Re03.g02670 Uncharacterized protein 4521 14771 25021
Mitochondrial F1 F0-ATP synthase
Re03.g02680 g subunit, putative 4522 14772 25022
Re03.g02690 ATP-dependent RNA helicase rok1 4523 14773 25023
Glucose-inducible SAM-dependent
Re03.g02700 methyltransferase Rrg1 , putative 4524 14774 25024
Vacuolar protein sorting-associated
Re03.g02710 protein Vps28, putative 4525 14775 25025
Ribosome assembly protein Noc2,
Re03.g02720 putative 4526 14776 25026
Re03.g02730 Potassium transporter, putative 4527 14777 25027 31399 32889
Molybdopterin cofactor biosynthetic
Re03.g02740 protein 4528 14778 25028 31400 32890
Re03.g02750 ABC ATPase, putative 4529 14779 25029
Re03.g02760 BTB/POZ domain protein 4530 14780 25030
BZIP transcription factor (LziP),
Re03.g02770 putative 4531 14781 25031
tRNA processing endoribonuclease
Re03.g02780 Trz1 , putative 4532 14782 25032
Re03.g02790 Acid phosphatase, putative 4533 14783 25033
Short chain
Re03.g02800 dehydrogenase/reductase, putative 4534 14784 25034 31401 32891
Re03.g02810 Putative uncharacterized protein 4535 14785 25035
Re03.g02820 Uncharacterized protein 4536 14786 25036
Function: RPS31 is a structural
Re03.g02830 protein of the small ribosomal 4537 14787 25037
Dihydrouridine synthase family
Re03.g02840 protein, putative 4538 14788 25038
Leucine carboxyl methyltransferase
Re03.g02850 superfamily 4539 14789 25039
Re03.g02860 RING zinc finger protein, putative 4540 14790 25040 31402 32892
DNA repair helicase, putative
Re03.g02870 EC=3.6.1.- 4541 14791 25041
DNA-directed RNA polymerase
Re03.g02880 EC=2.7.7.6 4542 14792 25042
U4/U6 small nuclear
Re03.g02890 ribonucleoprotein, putative 4543 14793 25043
snoRNP assembly factor Na l ,
Re03.g02900 putative 4544 14794 25044
Re03.g02910 Uncharacterized protein 4545 14795 25045 31403 32893
Re03.g02920 Uncharacterized protein 4546 14796 25046
Re03.g02930 Putative uncharacterized protein 4547 14797 25047
Integral membrane protein,
Re03.g02940 Mpv17/PMP22 family, putative 4548 14798 25048 Re03.g02950 Putative uncharacterized protein 4549 14799 25049
Re03.g02960 Histone H3 4550 14800 25050
Re03.g02970 Histone H4 4551 14801 25051
C2H2 transcription factor (Rpn4),
Re03.g02980 putative 4552 14802 25052
Re03.g02990 Uncharacterized protein 4553 14803 25053 31404 32894
15-hydroxyprostaglandin
Re03.g03000 dehydrogenase (NAD(+)) 4554 14804 25054
Pentafunctional polypeptide
Re03.g03010 (AroM), putative 4555 14805 25055
5'-3' exoribonuclease 2
Re03.g03020 EC=3.1.13.- 4556 14806 25056
Re03.g03030 Putative uncharacterized protein 4557 14807 25057
Re03.g03040 Uncharacterized protein 4558 14808 25058
Re03.g03050 WD repeat protein 4559 14809 25059
Re03.g03060 hypothetical protein 4560 14810 25060
Re03.g03070 Arsenical-resistance protein 4561 1481 1 25061
Re03.g03080 SET domain protein 4562 14812 25062
Extragenic suppressor of
Re03.g03090 kinetochore protein 4563 14813 25063
SNF7 family protein (Cta1 ),
Re03.g03100 putative 4564 14814 25064
Re03.g031 10 Transporter protein smf2 4565 14815 25065
Re03.g03120 Putative uncharacterized protein 4566 14816 25066
Re03.g03130 Putative uncharacterized protein 4567 14817 25067 31405 32895
3-ketoacyl-coA thiolase
Re03.g03140 peroxisomal A 4568 14818 25068
Re03.g03150 DlpA domain protein 4569 14819 25069
Re03.g03160 Uncharacterized protein 4570 14820 25070
Re03.g03170 Putative uncharacterized protein 4571 14821 25071
Re03.g03180 Histone acetyltransferase, putative 4572 14822 25072
Re03.g03190 hypothetical protein 4573 14823 25073
Re03.g03200 Uncharacterized protein 4574 14824 25074
Re03.g03210 Uncharacterized protein 4575 14825 25075
Re03.g03220 Carbonic anhydrase EC=4.2.1.1 4576 14826 25076
Remark: C. albicans 6C5 protein is
Re03.g03230 also useful in diagnostic tests 4577 14827 25077
Re03.g03240 Uncharacterized protein 4578 14828 25078
Re03.g03250 DUF409 domain protein 4579 14829 25079
Proteasome activator subunit 4,
Re03.g03260 putative 4580 14830 25080
Vacuolar ATPase 98 kDa subunit,
Re03.g03270 putative 4581 14831 25081
Fructose-1 ,6-bisphosphatase
Re03.g03280 Fbp1 , putative 4582 14832 25082
Re03.g03290 Putative uncharacterized protein 4583 14833 25083
Re03.g03300 Aha1 domain family 4584 14834 25084
Saccharopine dehydrogenase
Re03.g03310 Lys9, putative EC=1.5.1.10 4585 14835 25085 Re03.g03320 Prenyltransferase, putative 4586 14836 25086
Glycerol-3-phosphate
acyltransferase Sct1 , putative
Re03.g03330 EC=2.3.1.15 4587 14837 25087
Re03.g03340 Putative uncharacterized protein 4588 14838 25088
Re03.g03350 Uncharacterized protein 4589 14839 25089
Cell surface receptor/MFS
Re03.g03360 transporter (FLVCR), putative 4590 14840 25090
Re03.g03370 Dihydrodipicolinate synthetase 4591 14841 25091
Re03.g03380 Involucrin repeat protein 4592 14842 25092
Re03.g03390 Uncharacterized protein 4593 14843 25093
Re03.g03400 F-box and WD domain protein 4594 14844 25094
Rho guanyl nucleotide exchange
Re03.g03410 factor, putative 4595 14845 25095
Aminotransferase, classes I and II,
Re03.g03420 putative 4596 14846 25096
Thermatolerance membrane
Re03.g03430 protein Dlt1 4597 14847 25097 31406 32896
Sucrase/ferredoxin-like family
Re03.g03440 protein, putative 4598 14848 25098
C2H2 finger domain protein,
Re03.g03450 putative 4599 14849 25099
3-ketosteroid reductase
Re03.g03460 (AFlLorthologue AFUA_4G1 1500) 4600 14850 25100
Mannose-1 -phosphate
Re03.g03470 guanylyltransferase 4601 14851 25101 31407 32897
Re03.g03480 Putative uncharacterized protein 4602 14852 25102
Intermembrane space AAA
Re03.g03490 protease IAP-1 4603 14853 25103
Glycerol kinase, putative
Re03.g03500 EC=2.7.1.30 4604 14854 25104
Re03.g03510 Uncharacterized protein 4605 14855 25105 31408 32898
Vacuolar protein sorting-associated
Re03.g03520 protein vps13 4606 14856 25106
G-patch domain protein (TFIP1 1 ),
Re03.g03530 putative 4607 14857 25107
Re03.g03540 Superoxide dismutase EC=1.15.1.1 4608 14858 25108 31409 32899
Re03.g03550 Putative uncharacterized protein 4609 14859 25109
GINS complex subunit Psf3,
Re03.g03560 putative 4610 14860 251 10
Re03.g03570 Putative uncharacterized protein 461 1 14861 251 1 1
Re03.g03580 Uncharacterized protein 4612 14862 251 12
Alpha-ketoglutarate
dehydrogenase complex subunit
Re03.g03590 Kgd1 , putative EC=1.2.4.2 4613 14863 251 13 31410 32900
Re03.g03600 hypothetical protein 4614 14864 251 14
Re03.g03610 PHD finger domain protein 4615 14865 251 15
Re03.g03620 Carboxylesterase type B 4616 14866 251 16 3141 1 32901
Re03.g03630 Uncharacterized protein 4617 14867 251 17
Re03.g03640 hypothetical protein 4618 14868 251 18 Cytochrome P450 oxidoreductase
Re03.g03650 OrdA-like, putative 4619 14869 251 19 31412 32902
Re03.g03660 hypothetical protein 4620 14870 25120 31413 32903
Re03.g03670 Uncharacterized protein 4621 14871 25121
Re03.g03680 Predicted protein 4622 14872 25122
Re03.g03690 hypothetical protein 4623 14873 25123
Re03.g03700 hypothetical protein 4624 14874 25124
Leucine Rich Repeat domain
Re03.g03710 protein 4625 14875 25125
RNA polymerase II transcription
Re03.g03720 factor related protein, putative 4626 14876 25126
Re03.g03730 Putative uncharacterized protein 4627 14877 25127 31414 32904
PHD finger domain protein (Ing1 ),
putative (AFU orthologue
Re03.g03740 AFUA_4G1 1660) 4628 14878 25128
Re03.g03750 hypothetical protein 4629 14879 25129
Oxidoreductase, short-chain
Re03.g03760 dehydrogenase/reductase family 4630 14880 25130
Re03.g03770 Uncharacterized protein 4631 14881 25131
Re03.g03780 Uncharacterized protein 4632 14882 25132
Re03.g03800 Putative uncharacterized protein 4633 14883 25133
Re03.g03810 Putative uncharacterized protein 4634 14884 25134
Re03.g03820 hypothetical protein 4635 14885 25135
Re03.g03830 Putative uncharacterized protein 4636 14886 25136
Glycerol dehydrogenase (GldB),
Re03.g03840 putative 4637 14887 25137
Re03.g03850 Predicted protein 4638 14888 25138
Re03.g03860 Putative uncharacterized protein 4639 14889 25139
Re03.g03870 Putative uncharacterized protein 4640 14890 25140
Re03.g03880 Putative uncharacterized protein 4641 14891 25141
Re03.g03890 Uncharacterized protein 4642 14892 25142
Re03.g03900 Putative uncharacterized protein 4643 14893 25143
Re03.g03910 Putative uncharacterized protein 4644 14894 25144 31415 32905
Re03.g03920 ATP binding protein, putative 4645 14895 25145
Cell cycle control protein (Cwf19),
Re03.g03930 putative 4646 14896 25146
Re03.g03940 Glyoxylate reductase 4647 14897 25147
Re03.g03950 C6 finger domain protein, putative 4648 14898 25148
Re03.g03960 Formin binding protein, putative 4649 14899 25149
Tubulin-specific chaperone,
Re03.g03970 putative 4650 14900 25150
Re03.g03980 Splicing factor 3a subunit 2 4651 14901 25151
Serine/threonine protein kinase,
Re03.g03990 putative 4652 14902 25152
Re03.g04000 TIM complex component Tim54 4653 14903 25153
Acetyltransferase catalytic subunit
Re03.g04010 (NAT1), putative 4654 14904 25154
Caffeine-induced death protein
Re03.g04020 Cid2, putative 4655 14905 25155 Formamidopyrimidine-DNA
Re03.g04030 glycosylase, putative 4656 14906 25156
Re03.g04040 Uncharacterized protein 4657 14907 25157
Iron-sulfur cluster assembly
Re03.g04050 associated protein Nar1 , putative 4658 14908 25158
Metallothionein-I gene transcription
Re03.g04060 activator 4659 14909 25159
Anthranilate
phosphoribosyltransferase,
Re03.g04070 putative 4660 14910 25160
Re03.g04080 Uncharacterized protein 4661 1491 1 25161
Phosphatidylinositol phospholipase
Re03.g04090 C 4662 14912 25162
Biotin-dependent 2-oxo acid
dehydrogenases acyltransferase,
Re03.g04100 putative 4663 14913 25163 31416 32906
Thermoresistant gluconokinase
Re03.g041 10 family protein 4664 14914 25164
Vacuolar protein sorting-associated
Re03.g04120 protein 26, putative 4665 14915 25165
Endosomal peripheral membrane
Re03.g04130 protein 4666 14916 25166
Ubiquitin conjugating enzyme
Re03.g04140 (MmsB), putative 4667 14917 25167
Re03.g04150 Putative uncharacterized protein 4668 14918 25168 31417 32907
Re03.g04160 Uncharacterized protein 4669 14919 25169
Re03.g04170 TPR domain protein 4670 14920 25170
Re03.g04180 Histone deacetylase SIR2, putative 4671 14921 25171
RNA methylase family UPF0020
Re03.g04190 protein 4672 14922 25172
Re03.g04200 HIT domain protein 4673 14923 25173
Re03.g04210 G2/mitotic-specific cyclin-B 4674 14924 25174
Re03.g04220 50S ribosomal protein L2 4675 14925 25175
Re03.g04230 C6 transcription factor Prf, putative 4676 14926 25176
Re03.g04240 WD repeat-containing protein 4677 14927 25177
Re03.g04250 Putative uncharacterized protein 4678 14928 25178
Re03.g04260 Uncharacterized protein 4679 14929 25179
Re03.g04270 DNA replication helicase Dna2 4680 14930 25180
Re03.g04280 Putative uncharacterized protein 4681 14931 25181
Re03.g04290 Nitrilase, putitive 4682 14932 25182 31418 32908
Exosome complex exonuclease
Re03.g04300 exoribonuclease (Rrp44), putative 4683 14933 25183
Re03.g04310 LIM domain protein 4684 14934 25184
tRNA (guanine-N(7)-)-
Re03.g04320 methyltransferase EC=2.1.1.33 4685 14935 25185
ESCRT-II complex component
Re03.g04330 (Vps25), putative 4686 14936 25186
Re03.g04340 DNA repair protein Rtt107, putative 4687 14937 25187
Re03.g04350 Toxin biosynthesis protein, putative 4688 14938 25188
Re03.g04360 hypothetical protein 4689 14939 25189 Re03.g04370 Alkaline phytoceramidase 4690 14940 25190
Re03.g04380 Uncharacterized protein 4691 14941 25191
Re03.g04390 SSS family solute:Na+ symporter 4692 14942 25192
Re03.g04400 Uncharacterized protein 4693 14943 25193
Re03.g04410 Putative uncharacterized protein 4694 14944 25194 31419 32909
Re03.g04420 Gibberellin 20-oxidase, putative 4695 14945 25195
Re03.g04430 Uncharacterized protein 4696 14946 25196 31420 32910
Re03.g04440 Putative uncharacterized protein 4697 14947 25197 31421 3291 1
Re03.g04450 Cell differentiation protein rcdl 4698 14948 25198
Re03.g04460 PHD finger domain protein 4699 14949 25199
Re03.g04470 hypothetical protein 4700 14950 25200
Re03.g04480 hypothetical protein 4701 14951 25201
Re03.g04490 Uncharacterized protein 4702 14952 25202
Re03.g04500 Sulfate transporter family protein 4703 14953 25203
Conserved lysine-rich protein,
Re03.g04510 putative 4704 14954 25204
Re03.g04520 Putative uncharacterized protein 4705 14955 25205
Re03.g04530 BZIP transcription factor CpcA 4706 14956 25206 31422 32912
Asparagine synthase related
Re03.g04540 protein 4707 14957 25207
Guanine nucleotide exchange
Re03.g04550 factor Vps9, putative 4708 14958 25208
Re03.g04560 Uncharacterized protein 4709 14959 25209
Re03.g04570 hypothetical protein 4710 14960 25210 31423 32913
Re03.g04580 Glutamyl-tRNA synthetase 471 1 14961 2521 1
Re03.g04590 Calcium transporter 4712 14962 25212
Haloalkanoic acid dehalogenase,
Re03.g04600 putative 4713 14963 25213
Re03.g04610 Uncharacterized protein 4714 14964 25214
Re03.g04620 C6 transcription factor 4715 14965 25215
Re03.g04630 Uncharacterized protein 4716 14966 25216
Re03.g04640 Putative uncharacterized protein 4717 14967 25217 31424 32914
Re03.g04650 FAD-binding protein 4718 14968 25218
Re03.g04660 Uncharacterized protein 4719 14969 25219
Re03.g04670 Uncharacterized protein 4720 14970 25220
Putative uncharacterized protein
Re03.g04680 An01 g10280 4721 14971 25221 31425 32915
Re03.g04690 Polyketide synthase Fragment 4722 14972 25222
Re03.g04700 Uncharacterized protein 4723 14973 25223
Re03.g04710 Pc13g 10900 protein 4724 14974 25224
Re03.g04720 Homogentisate 1 ,2-dioxygenase 4725 14975 25225
Pyridine nucleotide-disulphide
Re03.g04730 oxidoreductase, putative 4726 14976 25226
Re03.g04740 HLH transcription factor, putative 4727 14977 25227
Re03.g04750 Nucleoside hydrolase, putative 4728 14978 25228
Re03.g04760 Uncharacterized protein 4729 14979 25229 31426 32916
COPII-coated vesicle protein
Re03.g04770 SurF4/Erv29, putative 4730 14980 25230
Re03.g04780 Uncharacterized protein 4731 14981 25231 Vegetative incompatibility protein
Re03.g04790 HET-E-1 4732 14982 25232 31427 32917
Gag/polymerase/env polyprotein,
Re03.g04800 putative 4733 14983 25233
Re03.g04810 Putative uncharacterized protein 4734 14984 25234
Re03.g04820 Putative uncharacterized protein 4735 14985 25235 31428 32918
Re03.g04830 Putative uncharacterized protein 4736 14986 25236
Small nuclear ribonucleoprotein
Re03.g04840 Lsm8, putative 4737 14987 25237
Re03.g04850 Uncharacterized protein 4738 14988 25238
Re03.g04860 Putative uncharacterized protein 4739 14989 25239
Re03.g04870 Ribosomal protein 4740 14990 25240
GNAT family acetyltransferase,
Re03.g04880 putative 4741 14991 25241
Re03.g04890 Putative uncharacterized protein 4742 14992 25242
Re03.g04900 ADP-ribosylation factor, putative 4743 14993 25243
Re03.g04910 Putative uncharacterized protein 4744 14994 25244
Re03.g04920 Putative uncharacterized protein 4745 14995 25245
Re03.g04930 Uncharacterized protein 4746 14996 25246 31429 32919
Cyanide hydratase/nitrilase,
Re03.g04940 putative 4747 14997 25247
Re03.g04950 Pc12g02660 protein 4748 14998 25248
Re03.g04960 Putative amidohydrolase protein 4749 14999 25249
Re03.g04970 Acetamidase 4750 15000 25250
Re03.g04980 Ethanolamine kinase, putative 4751 15001 25251
Re03.g04990 CORD and CS domain protein 4752 15002 25252
Re03.g05000 Glutaredoxin domain protein 4753 15003 25253 31430 32920
HpcH/Hpal aldolase/citrate lyase
Re03.g05010 family protein 4754 15004 25254
Re03.g05020 hypothetical protein 4755 15005 25255
Re03.g05030 hypothetical protein 4756 15006 25256
Re03.g05040 hypothetical protein 4757 15007 25257 31431 32921
Re03.g05050 hypothetical protein 4758 15008 25258
Re03.g05060 Uncharacterized protein 4759 15009 25259
Re03.g05070 hypothetical protein 4760 15010 25260
Re03.g05080 Uncharacterized protein 4761 1501 1 25261
Re03.g05090 Uncharacterized protein 4762 15012 25262
DUF1688 domain-containing
Re03.g05100 protein 4763 15013 25263
Re03.g051 10 Uncharacterized protein 4764 15014 25264 31432 32922
Re03.g05120 Uncharacterized protein 4765 15015 25265
Re03.g05130 Uncharacterized protein 4766 15016 25266
Putative carbohydrate esterase
Re03.g05140 family 5 protein 4767 15017 25267 31433 32923
Putative carboxyl esterase family
Re03.g05150 protein (Secreted protein) protein 4768 15018 25268 31434 32924
Re03.g05160 hypothetical protein 4769 15019 25269 31435 32925
Re03.g05180 Acyl-CoA dehydrogenase 4770 15020 25270
Re03.g05190 hypothetical protein 4771 15021 25271 31436 32926 Re03.g05200 Endopolyphosphatase EC=3.6.1.10 4772 15022 25272 31437 32927
Re03.g05210 Uncharacterized protein 4773 15023 25273 31438 32928
Re03.g05220 Putative uncharacterized protein 4774 15024 25274
Re03.g05230 hypothetical protein 4775 15025 25275
Monooxygenase FAD-binding
Re03.g05240 protein 4776 15026 25276 31439 32929
Re03.g05250 Putative uncharacterized protein 4777 15027 25277
Endosomal cargo receptor (P24),
Re03.g05260 putative 4778 15028 25278 31440 32930
Re03.g05270 Putative uncharacterized protein 4779 15029 25279
Myosin class II heavy chain (MHC),
Re03.g05290 putative 4780 15030 25280
Re03.g05300 Predicted protein 4781 15031 25281
Re03.g05310 hypothetical protein 4782 15032 25282
Re03.g05320 60S ribosomal protein L37a 4783 15033 25283
Saccharopine dehydrogenase,
Re03.g05330 putative 4784 15034 25284
Succinate:fumarate antiporter
Re03.g05340 (Acr1 ), putative 4785 15035 25285
Actin monomer binding protein,
Re03.g05350 putative 4786 15036 25286
Re03.g05360 Uncharacterized protein 4787 15037 25287
Re03.g05370 Pinin/SDK/memA domain protein 4788 15038 25288
Re03.g05380 Epoxide hydrolase 4789 15039 25289
Re03.g05390 Uncharacterized protein 4790 15040 25290
Re03.g05400 Putative uncharacterized protein 4791 15041 25291
Re03.g05410 CAF1 family ribonuclease, putative 4792 15042 25292
Re03.g05420 50S ribosomal subunit L30 4793 15043 25293
Re03.g05430 Uncharacterized protein 4794 15044 25294
Re03.g05440 Putative uncharacterized protein 4795 15045 25295
Re03.g05450 Uncharacterized protein 4796 15046 25296
Re03.g05460 Uncharacterized protein 4797 15047 25297
Re03.g05470 Predicted protein 4798 15048 25298
Re03.g05480 Uncharacterized protein 4799 15049 25299
Re03.g05490 Nuclear export protein Noc3 4800 15050 25300
Re03.g05500 Ribosome biogenesis protein NIP7 4801 15051 25301
Defective in cullin neddylation
Re03.g05510 protein 4802 15052 25302
Re03.g05520 Putative uncharacterized protein 4803 15053 25303
Re03.g05530 Uncharacterized protein 4804 15054 25304
Re03.g05540 Putative uncharacterized protein 4805 15055 25305
Re03.g05550 Uncharacterized protein 4806 15056 25306
Re03.g05560 Cell division control protein Cdc48 4807 15057 25307
Re03.g05570 Predicted protein 4808 15058 25308
Re03.g05580 Putative uncharacterized protein 4809 15059 25309 31441 32931
Re03.g05590 Uncharacterized protein 4810 15060 25310
Re03.g05600 hypothetical protein 481 1 15061 2531 1 31442 32932
Re03.g05610 Uncharacterized protein 4812 15062 25312
Re03.g05620 Uncharacterized protein 4813 15063 25313 Re03.g05630 Uncharacterized protein 4814 15064 25314
MAPKKK cascade protein kinase
Re03.g05640 regulator Ste50 4815 15065 25315
Re03.g05650 Na+/H+ antiporter Nha1 4816 15066 25316
Re03.g05660 Sorting nexin Mvp1 4817 15067 25317
Re03.g05670 Uncharacterized protein 4818 15068 25318
Re03.g05680 Uncharacterized protein 4819 15069 25319
Re03.g05690 Putative uncharacterized protein 4820 15070 25320
GTP binding protein (SPG1 ),
Re03.g05700 putative 4821 15071 25321
Re03.g05710 Uncharacterized protein 4822 15072 25322
C2H2 transcription factor (AmdX),
Re03.g05720 putative 4823 15073 25323
MFS glucose transporter, putative
Re03.g05730 (AFU.orthologue AFUA_3G14170) 4824 15074 25324 31443 32933
Re03.g05740 hypothetical protein 4825 15075 25325 31444 32934
Ceramide synthase membrane
Re03.g05750 component (LAG1), putative 4826 15076 25326
Re03.g05760 Putative uncharacterized protein 4827 15077 25327 31445 32935
Re03.g05770 Alpha-amylase, putative 4828 15078 25328 31446 32936
Re03.g05780 Glucoamylase 4829 15079 25329 31447 32937
Re03.g05790 Putative uncharacterized protein 4830 15080 25330 31448 32938
Cullin binding protein CanA,
Re03.g05800 putative 4831 15081 25331
Cullin binding protein CanA,
Re03.g05810 putative 4832 15082 25332
Similarity to hypothetical protein
Re03.g05820 EAA58284.1 4833 15083 25333
Re03.g05830 pH signal transduction protein PalH 4834 15084 25334
Re03.g05840 Putative uncharacterized protein 4835 15085 25335
Aspartic endopeptidase
Re03.g05850 Pep1/aspergillopepsin F 4836 15086 25336 31449 32939
Re03.g05860 C6 transcription factor, putative 4837 15087 25337
UV radiation resistance protein
Re03.g05870 (UVRAG), putative 4838 15088 25338
Re03.g05880 Uncharacterized protein 4839 15089 25339
Re03.g05890 Protein phosphatase 2C, putative 4840 15090 25340
Re03.g05900 SNF7 family protein 4841 15091 25341
Re03.g05910 Transmembrane GTPase Fzo1 4842 15092 25342
Re03.g05920 BRCT domain protein 4843 15093 25343 31450 32940
ATP-dependent DNA helicase PIF1
Re03.g05930 EC=3.6.4.12 4844 15094 25344
Re03.g05940 YjeF_N domain protein 4845 15095 25345
Peptidyl-prolyl cis-trans isomerase,
Re03.g05950 putative 4846 15096 25346
Re03.g05960 Uncharacterized protein 4847 15097 25347
Carboxyphosphonoenol pyruvate
Re03.g05970 mutase 4848 15098 25348
Re03.g05980 Putative uncharacterized protein 4849 15099 25349 Re03.g05990 Protein H0L1 , putative 4850 15100 25350
Re03.g06000 hypothetical protein 4851 15101 25351
Re03.g06010 Uncharacterized protein 4852 15102 25352
Triosephosphate isomerase
Re03.g06020 EC=5.3.1.1 4853 15103 25353
Mitochondrial distribution and
Re03.g06030 morphology protein 10 4854 15104 25354
60S acidic ribosomal protein PO,
Re03.g06040 putative 4855 15105 25355
U1 small nuclear ribonucleoprotein
Re03.g06050 70 kDa 4856 15106 25356
Mitochondrial ribosomal protein
Re03.g06060 L43, putative 4857 15107 25357
Re03.g06070 Uncharacterized protein 4858 15108 25358
Re03.g06080 hypothetical protein 4859 15109 25359
Re03.g06090 Putative uncharacterized protein 4860 151 10 25360
Ribosome biogenesis protein Rial ,
Re03.g06100 putative 4861 151 1 1 25361
Re03.g061 10 3'-5' exoribonuclease 4862 151 12 25362 31451 32941
Vacuolar armadillo repeat protein
Re03.g06120 Vac8, putative 4863 151 13 25363
Re03.g06130 FHA domain protein 4864 151 14 25364
Similarity to hypothetical protein
Re03.g06140 alr2987 4865 151 15 25365
Re03.g06150 Uncharacterized protein 4866 151 16 25366
Re03.g06160 Uncharacterized protein 4867 151 17 25367
Re03.g06170 hypothetical protein 4868 151 18 25368
Remark: belongs to the S30E
Re03.g06180 family of ribosomal proteins 4869 151 19 25369
Re03.g06190 Vacuolar protein sorting vps16 4870 15120 25370
Re03.g06200 Uncharacterized protein 4871 15121 25371
Re03.g06210 Uncharacterized protein 4872 15122 25372
EF-hand superfamily
Re03.g06220 Ca2+modulated protein 4873 15123 25373
Re03.g06230 Thioredoxin, putative 4874 15124 25374
Re03.g06240 Kinesin family protein 4875 15125 25375 31452 32942
Translation initiation factor eif-2b
Re03.g06250 delta subunit 4876 15126 25376 31453 32943
Re03.g06260 Apc13 domain protein 4877 15127 25377
Re03.g06270 DNA polymerase alpha subunit B 4878 15128 25378
Re03.g06280 CRAL/TRIO domain protein 4879 15129 25379
Sn l protein kinase complex
Re03.g06290 subunit Snf4, putative 4880 15130 25380
Re03.g06300 Uncharacterized protein 4881 15131 25381
Re03.g06310 Putative uncharacterized protein 4882 15132 25382 31454 32944
BZIP transcription factor (Atf21 ),
Re03.g06320 putative 4883 15133 25383 31455 32945
Re03.g06330 MFS quinate transporter, putative 4884 15134 25384
Re03.g06340 Arylsulfatase 4885 15135 25385 Re03.g06350 Xaa-pro dipeptidase, putative 4886 15136 25386
Re03.g06360 Putative uncharacterized protein 4887 15137 25387
Re03.g06370 Iron transporter 4888 15138 25388
Re03.g06380 Kelch repeat protein protein 4889 15139 25389
Mitochondrial 3-hydroxyisobutyryl-
Re03.g06390 CoA hydrolase, putative 4890 15140 25390
Mitochondrial 54S ribosomal
Re03.g06400 protein YmL6 4891 15141 25391
Mitochondrial 54S ribosomal
Re03.g06410 protein YmL35 4892 15142 25392
Mitochondrial inner membrane
Re03.g06420 protease subunit 1 , putative 4893 15143 25393 31456 32946
Re03.g06430 DUF1264 domain protein 4894 15144 25394
Hydroxyacylglutathione hydrolase,
Re03.g06440 putative 4895 15145 25395
Putative uncharacterized protein
Re03.g06450 An14g06350 4896 15146 25396
Re03.g06460 Putative uncharacterized protein 4897 15147 25397
Re03.g06470 hypothetical protein 4898 15148 25398 31457 32947
Re03.g06480 hypothetical protein 4899 15149 25399
Re03.g06490 hypothetical protein 4900 15150 25400
Re03.g06500 hypothetical protein 4901 15151 25401
Re03.g06510 hypothetical protein 4902 15152 25402
Re03.g06520 NAD+ kinase, putative 4903 15153 25403
Re03.g06530 BET3 family protein 4904 15154 25404
Microfibrillar-associated protein
Re03.g06540 MfaP1 , putative 4905 15155 25405
Re03.g06550 Uncharacterized protein 4906 15156 25406
Re03.g06560 Uncharacterized protein 4907 15157 25407
Small nuclear ribonucleoprotein
Re03.g06570 SmD2, putative 4908 15158 25408
Dihydroxyacetone kinase (DakA),
Re03.g06580 putative 4909 15159 25409
Ubiquitin ligase subunit CulD,
Re03.g06590 putative 4910 15160 25410
Re03.g06600 Uncharacterized protein 491 1 15161 2541 1
Phosphotidylinositol kinase Tel l ,
Re03.g06610 putative 4912 15162 25412
Re03.g06620 Putative uncharacterized protein 4913 15163 25413
Re03.g06630 UPF0052 domain protein 4914 15164 25414
C3HC4 type (RING finger) zinc
Re03.g06640 finger containing protein 4915 15165 25415
Re03.g06650 DNA polymerase gamma 4916 15166 25416
Re03.g06660 Major royal jelly protein 4917 15167 25417 31458 32948
CorA family metal ion transporter,
Re03.g06670 putative 4918 15168 25418
Re03.g06680 Putative uncharacterized protein 4919 15169 25419
DNA excision repair protein
Re03.g06690 (Rad5), putative 4920 15170 25420 Re03.g06700 Uncharacterized protein 4921 15171 25421
Re03.g06710 hypothetical protein 4922 15172 25422
GTP binding protein (GTPBP1 ),
Re03.g06720 putative 4923 15173 25423
U6 small nuclear ribonucleoprotein
(Lsm3), putative (AFU orthologue
Re03.g06730 AFUA_5G12570) 4924 15174 25424
Re03.g06740 Uncharacterized protein Fragment 4925 15175 25425
N-acetylglucosaminyl- phosphatidylinositol deacetylase,
Re03.g06750 putative 4926 15176 25426 31459 32949
Re03.g06760 hypothetical protein 4927 15177 25427
Arrestin (Or S-antigen), N-terminal
domain protein (AFU orthologue
Re03.g06770 AFUA_5G12530) 4928 15178 25428 31460 32950
Re03.g06780 Uncharacterized protein 4929 15179 25429 31461 32951
Re03.g06790 Putative uncharacterized protein 4930 15180 25430 31462 32952
Stress response protein Rds1 ,
Re03.g06800 putative 4931 15181 25431 31463 32953
Short chain
Re03.g06810 dehydrogenase/reductase family 4932 15182 25432 31464 32954
Re03.g06820 Pc21 g07730 protein 4933 15183 25433
2-amino-3-carboxymuconate-6-
Re03.g06830 semialdehyde decarboxylase 4934 15184 25434
Re03.g06840 Uncharacterized protein 4935 15185 25435
Re03.g06850 Cell cycle control protein 4936 15186 25436
Re03.g06860 Uncharacterized protein 4937 15187 25437
Re03.g06870 Putative uncharacterized protein 4938 15188 25438 31465 32955
Re03.g06880 Ankyrin repeat protein 4939 15189 25439
Re03.g06890 Putative uncharacterized protein 4940 15190 25440
Re03.g06900 Uncharacterized protein 4941 15191 25441
Re03.g06910 Putative uncharacterized protein 4942 15192 25442
Re03.g06920 Putative uncharacterized protein 4943 15193 25443
Re03.g06930 Similar to MFS sugar transporter 4944 15194 25444
Re03.g06940 Reverse transcriptase, putative 4945 15195 25445
Re03.g06950 Uncharacterized protein 4946 15196 25446
Re03.g06960 Putative uncharacterized protein 4947 15197 25447
Re03.g06970 Putative uncharacterized protein 4948 15198 25448
Re03.g06980 Pc22g24560 protein 4949 15199 25449
Re03.g06990 Putative uncharacterized protein 4950 15200 25450
Putative transferase caf 17,
Re03.g07000 mitochondrial EC=2.1 Precursor 4951 15201 25451
Re03.g07010 Decapping enzyme Dcp2, putative 4952 15202 25452
Re03.g07020 Putative uncharacterized protein 4953 15203 25453
Cytoplasmic tRNA 2-thiolation
Re03.g07030 protein 2 4954 15204 25454
Integral membrane protein (Ptm1 ),
Re03.g07040 putative 4955 15205 25455 31466 32956
Re03.g07050 Putative uncharacterized protein 4956 15206 25456 WD domain, G-beta repeat
Re03.g07060 containing protein 4957 15207 25457 31467 32957
Mitochondrial oxaloacetate
Re03.g07070 transporter (Oac), putative 4958 15208 25458 31468 32958
Re03.g07080 Uncharacterized protein 4959 15209 25459
Re03.g07090 Uncharacterized protein 4960 15210 25460
Re03.g07100 hypothetical protein 4961 1521 1 25461
Re03.g071 10 hypothetical protein 4962 15212 25462
Re03.g07120 Putative uncharacterized protein 4963 15213 25463
Re03.g07130 Predicted protein 4964 15214 25464 31469 32959
Re03.g07140 Choline dehydrogenase 4965 15215 25465
Re03.g07150 Uncharacterized protein 4966 15216 25466 31470 32960
Re03.g07160 Uncharacterized protein Fragment 4967 15217 25467
Re03.g07170 Uncharacterized protein 4968 15218 25468
Re03.g07180 WD repeat protein 4969 15219 25469
Re03.g07190 Uncharacterized protein 4970 15220 25470
Re03.g07200 Putative uncharacterized protein 4971 15221 25471
Re03.g07210 Uncharacterized protein 4972 15222 25472
Re03.g07220 Uncharacterized protein Fragment 4973 15223 25473
Re03.g07230 Putative uncharacterized protein 4974 15224 25474
rRNA processing protein (Ebp2),
Re03.g07240 putative 4975 15225 25475
Re03.g07250 Putative uncharacterized protein 4976 15226 25476
Disulfide isomerase (TigA),
Re03.g07260 putative 4977 15227 25477 31471 32961
Re03.g07270 XPG l-region protein 4978 15228 25478
Oxidoreductase, 20G-Fe(ll)
Re03.g07280 oxygenase family, putative 4979 15229 25479
MYND domain protein (SamB),
Re03.g07290 putative 4980 15230 25480
Re03.g07300 hypothetical protein 4981 15231 25481 31472 32962
Re03.g07310 hypothetical protein 4982 15232 25482
G protein complex beta subunit
Re03.g07320 SfaD 4983 15233 25483
Transposon-encoded proteins with
Re03.g07330 TYA 4984 15234 25484
Re03.g07340 hypothetical protein 4985 15235 25485 31473 32963
Re03.g07350 Phosducin, putative 4986 15236 25486
Transcription initiation factor
Re03.g07360 subunit (TAF30), putative 4987 15237 25487
Ran-specific GTPase-activating
Re03.g07370 protein 1 , putative 4988 15238 25488
Re03.g07380 Uncharacterized protein 4989 15239 25489
Re03.g07390 Acetyl xylan esterase 4990 15240 25490 31474 32964
Re03.g07400 Uncharacterized protein 4991 15241 25491 31475 32965
Small oligopeptide transporter,
Re03.g07410 OPT family 4992 15242 25492
Alpha-1 ,2-mannosyltransferase
Re03.g07420 (Kre5), putative EC=2.4.1.131 4993 15243 25493 Re03.g07430 PH domain protein 4994 15244 25494
Integral membrane protein,
Re03.g07440 putative 4995 15245 25495
Rab small monomeric GTPase
Re03.g07450 Rab7, putative 4996 15246 25496
Re03.g07460 Autophagy protein Apg16, putative 4997 15247 25497
Histone-lysine N- methyltransferase, H3 lysine-79
Re03.g07470 specific EC=2.1.1.43 4998 15248 25498
AdoMet-dependent rRNA
Re03.g07480 methyltransferase spbl EC=2.1.1.- 4999 15249 25499
Re03.g07490 Putative uncharacterized protein 5000 15250 25500
Re03.g07500 Putative uncharacterized protein 5001 15251 25501
Re03.g07510 Putative uncharacterized protein 5002 15252 25502
Re03.g07520 C2H2 transcription factor, putative 5003 15253 25503
Re03.g07530 DNA Iigase EC=6.5.1.1 5004 15254 25504
Re03.g07540 Uncharacterized protein 5005 15255 25505
C6 transcription factor (NirA),
Re03.g07550 putative 5006 15256 25506
Serine/threonine-protein
Re03.g07560 phosphatase EC=3.1.3.16 5007 15257 25507
Putative uncharacterized protein
Re03.g07570 Fragment 5008 15258 25508 31476 32966
Dol-P-Man:Man(5)GlcNAc(2)-PP- Dol alpha-1 ,3-mannosyltransferase
Re03.g07580 EC=2.4.1.258 5009 15259 25509
Re03.g07590 Eukaryotic initiation factor 1A 5010 15260 25510
Re03.g07600 Putative uncharacterized protein 501 1 15261 2551 1
Re03.g07610 Protein kinase c 5012 15262 25512
Tubulin-specific chaperone D,
Re03.g07620 putative 5013 15263 25513
Small nuclear ribonucleoprotein
Re03.g07630 U1 a,U2b 5014 15264 25514
Vacuolar ATP synthase subunit D,
Re03.g07640 putative EC=3.6.3.14 5015 15265 25515 31477 32967
Re03.g07650 mRNA splicing factor 5016 15266 25516
Re03.g07660 Putative uncharacterized protein 5017 15267 25517
Rho guanyl nucleotide exchange
Re03.g07670 factor, putative 5018 15268 25518
Re03.g07680 PP-loop family protein 5019 15269 25519
Re03.g07690 WD repeat protein 5020 15270 25520
Re03.g07700 Putative uncharacterized protein 5021 15271 25521
Re03.g07710 DUF985 domain protein 5022 15272 25522
Re03.g07720 Autophagy-related protein 18 5023 15273 25523
Re03.g07730 Leucine carboxyl methyltransferase 5024 15274 25524
Protein tyrosine phosphatase
Re03.g07740 Pps1 , putative 5025 15275 25525
Re03.g07750 Uncharacterized protein 5026 15276 25526
Re03.g07760 Uncharacterized protein 5027 15277 25527 Re03.g07770 Putative uncharacterized protein 5028 15278 25528
26S proteasome regulatory subunit
Re03.g07780 rpn-1 5029 15279 25529
RI01 family protein kinase,
putative (AFU orthologue
Re03.g07790 AFUA_5G1 1730) 5030 15280 25530
Mitochondrial ribosomal protein
Re03.g07800 L23, putative 5031 15281 25531
Lon protease homolog 2,
Re03.g07810 peroxisomal EC=3.4.21.- 5032 15282 25532
Re03.g07820 Hydroxymethylbilane synthase 5033 15283 25533
TOR signalling pathway regulator
Re03.g07830 (TapA), putative 5034 15284 25534
Re03.g07840 RNase3 domain protein 5035 15285 25535
Re03.g07850 Dynein heavy chain 5036 15286 25536
Re03.g07860 Putative uncharacterized protein 5037 15287 25537
Oxidative stress protein Svf1 ,
Re03.g07870 putative 5038 15288 25538
60S ribosomal protein L19,
Re03.g07880 mitochondrial 5039 15289 25539
Re03.g07890 hypothetical protein 5040 15290 25540
Re03.g07900 Protein kinase, putative 5041 15291 25541
Mitochondrial carrier protein (Pet8),
Re03.g07910 putative 5042 15292 25542
Re03.g07920 Uncharacterized protein 5043 15293 25543
Secretory pathway protein Ssp120,
Re03.g07930 putative 5044 15294 25544 31478 32968
Re03.g07940 Uncharacterized protein 5045 15295 25545
Pre-mRNA splicing factor ATP-
Re03.g07950 dependent RNA helicase Prp43 5046 15296 25546
Re03.g07960 Protein methyltransferase RmtC 5047 15297 25547
Glycerophosphocholine
Re03.g07970 phosphodiesterase Gde1 Fragment 5048 15298 25548
Re03.g07980 hypothetical protein 5049 15299 25549
Re03.g07990 hypothetical protein 5050 15300 25550
Actin cytoskeleton organization
Re03.g08000 protein (Cro1 ), putative 5051 15301 25551
Transcription factor TFIIH subunit
Re03.g08010 Tfb4 5052 15302 25552
Re03.g08020 Asparaginase family protein 5053 15303 25553
Arp2/3 complex subunit (Arp3),
Re03.g08030 putative 5054 15304 25554
Re03.g08040 tRNA(M5U54)methyltransferase 5055 15305 25555
Mitochondrial 37S ribosomal
Re03.g08050 protein MRPS5 5056 15306 25556 31479 32969
Re03.g08060 Putative uncharacterized protein 5057 15307 25557
Serine/threonine protein kinase
Re03.g08070 (Nrc-2), putative 5058 15308 25558
Re03.g08080 Uncharacterized protein 5059 15309 25559
Re03.g08090 Uncharacterized protein 5060 15310 25560 Re03.g08100 Putative uncharacterized protein 5061 1531 1 25561 31480 32970
Re03.g081 10 MYB DNA binding protein 5062 15312 25562
TFIID and and SAGA complex
Re03.g08120 TAF10 subunit, putative 5063 15313 25563
Re03.g08130 Ribosomal protein S19, putative 5064 15314 25564
Re03.g08140 Inositol polyphosphate multikinase 5065 15315 25565
Re03.g08150 Putative uncharacterized protein 5066 15316 25566
Re03.g08160 Quinone oxidoreductase, putative 5067 15317 25567 31481 32971
Re03.g08170 Putative uncharacterized protein 5068 15318 25568
mRNA cleavage and
Re03.g08180 polyadenylation factor CLP1 5069 15319 25569
Putative APSES transcription factor
Re03.g08190 (Eurofung) 5070 15320 25570
Re03.g08200 Putative uncharacterized protein 5071 15321 25571
Protein phosphatase type 2A
Re03.g08210 protein 5072 15322 25572
Re03.g08220 Uncharacterized protein 5073 15323 25573
Re03.g08230 Urea active transporter, putative 5074 15324 25574
Re03.g08240 Uncharacterized protein 5075 15325 25575
Re03.g08250 Putative uncharacterized protein 5076 15326 25576
Ndc80 complex component Nuf2,
Re03.g08260 putative 5077 15327 25577
Translation initiation factor elF-2B
Re03.g08270 alpha subunit, putative 5078 15328 25578
Re03.g08280 hypothetical protein 5079 15329 25579 31482 32972
Re03.g08290 hypothetical protein 5080 15330 25580
Re03.g08300 Uncharacterized protein 5081 15331 25581
Re03.g08310 Putative uncharacterized protein 5082 15332 25582
Re03.g08320 Thioredoxin 5083 15333 25583
Re03.g08330 MFS transporter 5084 15334 25584
Re03.g08340 Uncharacterized protein 5085 15335 25585
Re03.g08350 Pc21 g05600 protein 5086 15336 25586
Re03.g08360 Polyglutamate biosynthesis protein 5087 15337 25587
Re03.g08370 OTU-like cysteine protease 5088 15338 25588
Re03.g08380 D-amino acid oxidase EC= .4.3.3 5089 15339 25589 31483 32973
Re03.g08390 GATA factor SREP 5090 15340 25590
Re03.g08400 hypothetical protein 5091 15341 25591
Re03.g08410 COPI-coated vesicle protein 5092 15342 25592
Re03.g08420 Uncharacterized protein 5093 15343 25593
Re03.g08430 Uncharacterized protein 5094 15344 25594
Re03.g08440 hypothetical protein 5095 15345 25595
Re03.g08450 Oxidoreductase 5096 15346 25596
Re03.g08460 Putative uncharacterized protein 5097 15347 25597
Re03.g08470 MFS multidrug transporter, putative 5098 15348 25598
Re03.g08480 hypothetical protein 5099 15349 25599
RAS small monomeric GTPase
Re03.g08490 RasA 5100 15350 25600
Molybdopterin binding domain
Re03.g08500 protein 5101 15351 25601 31484 32974 Re03.g08510 GMF family protein 5102 15352 25602
Re03.g08520 hypothetical protein 5103 15353 25603
Re03.g08530 hypothetical protein 5104 15354 25604
Re03.g08540 Putative uncharacterized protein 5105 15355 25605
Re03.g08550 hypothetical protein 5106 15356 25606
Re03.g08560 hypothetical protein 5107 15357 25607 31485 32975
Chromatin remodeling complex
WSTF-ISWI, small subunit
Re03.g08570 Fragment 5108 15358 25608
Re03.g08580 Uncharacterized protein 5109 15359 25609
Ribonuclease P complex subunit
Re03.g08590 Pop4, putative 51 10 15360 25610
tRNA-splicing endonuclease
Re03.g08600 subunit sen34 51 1 1 15361 2561 1
Re03.g08610 PAXNEB protein superfamily 51 12 15362 25612
DNA-directed RNA polymerases i,
Re03.g08620 ii, and iii 145 kDa polypeptide 51 13 15363 25613
Thiamin pyrophosphokinase-
Re03.g08630 related protein 51 14 15364 25614
Re03.g08640 DUF775 domain protein 51 15 15365 25615
Re03.g08650 Pc21 g05560 protein 51 16 15366 25616
Re03.g08660 hypothetical protein 51 17 15367 25617
Re03.g08670 MFS transporter, putative 51 18 15368 25618
Re03.g08680 C6 transcription factor 51 19 15369 25619
Re03.g08690 hypothetical protein 5120 15370 25620
Re03.g08700 WD repeat protein 5121 15371 25621
ATP dependent RNA helicase
Re03.g08710 (Dbp7), putative 5122 15372 25622
Re03.g08720 Pantoate-beta-alanine ligase 5123 15373 25623
Re03.g08730 Acyltransferase, putative 5124 15374 25624
Re03.g08740 PaxU 5125 15375 25625
Re03.g08750 Putative uncharacterized protein 5126 15376 25626
Re03.g08760 Putative uncharacterized protein 5127 15377 25627
Re03.g08770 Putative uncharacterized protein 5128 15378 25628
Re03.g08780 Uncharacterized protein 5129 15379 25629
Re03.g08790 Predicted protein 5130 15380 25630
Re03.g08800 Ammonium transporter MepA 5131 15381 25631
Nucleoside diphosphatase (Ynd1 ),
Re03.g08810 putative 5132 15382 25632 31486 32976
Small nuclear ribonucleoprotein
Re03.g08820 U2, A 5133 15383 25633
Re03.g08830 Putative uncharacterized protein 5134 15384 25634
Re03.g08840 Putative uncharacterized protein 5135 15385 25635
Re03.g08850 Uncharacterized protein 5136 15386 25636
Re03.g08860 Predicted protein 5137 15387 25637
Re03.g08870 hypothetical protein 5138 15388 25638
Re03.g08880 DUF221 domain protein, putative 5139 15389 25639
Re03.g08890 Putative uncharacterized protein 5140 15390 25640
Re03.g08900 DNA replication licensing factor 5141 15391 25641 31487 32977 Mcm6, putative
Re03.g08910 Predicted protein 5142 15392 25642
Pyridoxamine phosphate oxidase,
Re03.g08920 putative 5143 15393 25643
FAD dependent oxidoreductase
Re03.g08930 superfamily 5144 15394 25644
Re03.g08940 Uncharacterized protein 5145 15395 25645 31488 32978
Stress response RCI peptide,
Re03.g08950 putative 5146 15396 25646 31489 32979
Mitochondrion biogenesis protein
Re03.g08960 (She9), putative 5147 15397 25647
Re03.g08970 hypothetical protein 5148 15398 25648
Phenylalanine ammonia-lyase
Re03.g08980 EC=4.3.1.24 5149 15399 25649
Re03.g08990 hypothetical protein 5150 15400 25650 31490 32980
Voltage-gated chloride channel,
Re03.g09000 putative 5151 15401 25651
Re03.g09010 Predicted protein 5152 15402 25652 31491 32981
Cytochrome b-d complex subunit
Re03.g09020 Rieske, mitochondrial EC=1.10.2.2 5153 15403 25653 31492 32982
Re03.g09030 Pentatricopeptide repeat protein 5154 15404 25654
Re03.g09040 hypothetical protein 5155 15405 25655
Re03.g09050 Phosphomevalonate kinase 5156 15406 25656
Re03.g09060 Glucoamylase EC=3.2.1.3 5157 15407 25657 31493 32983
Alpha-amylase, putative
Re03.g09070 EC=3.2.1.1 5158 15408 25658 31494 32984
Re03.g09080 Uncharacterized protein 5159 15409 25659
Proteasome maturation factor
Re03.g09090 Ump1 , putative 5160 15410 25660
Re03.g09100 37S ribosomal protein S12 5161 1541 1 25661
Alpha-1 ,2-mannosyltransferase
Re03.g091 10 (Kre2), putative 5162 15412 25662 31495 32985
Re03.g09120 Topisomerase II associated protein 5163 15413 25663
UDP-glucose 4-epimerase
Re03.g09130 EC=5.1.3.2 5164 15414 25664
Oxidoreductase, short chain
Re03.g09140 dehydrogenase/reductase family 5165 15415 25665
Re03.g09150 G-patch domain protein, putative 5166 15416 25666
Re03.g09160 Sec1 family superfamily 5167 15417 25667
ATP-dependent RNA helicase
Re03.g09170 SUV3 5168 15418 25668
RNA helicase-like splicing factor
Re03.g09180 (HRH1 ), putative 5169 15419 25669
Re03.g09190 Uncharacterized protein 5170 15420 25670
Re03.g09200 Uncharacterized protein 5171 15421 25671
Re03.g09210 C6 transcription factor, putative 5172 15422 25672
Sodium/calcium transporter,
Re03.g09220 putative 5173 15423 25673
Putative fructosyl amine:oxygen
Re03.g09230 oxidoreductase protein 5174 15424 25674 Re03.g09240 C6 zinc finger domain protein 5175 15425 25675
Re03.g09250 Reverse transcriptase, putative 5176 15426 25676
Re03.g09260 Putative uncharacterized protein 5177 15427 25677
Re03.g09270 hypothetical protein 5178 15428 25678
Pre-rRNA processing protein Esf 1 ,
Re03.g09280 putative 5179 15429 25679
Re03.g09290 Uridine kinase EC=2.7.1.48 5180 15430 25680
Re03.g09300 Putative uncharacterized protein 5181 15431 25681
NADH-ubiquinone oxidoreductase
Re03.g09310 subunit 5182 15432 25682
Sister chromatid cohesion protein
Re03.g09320 Mis4 5183 15433 25683
DNA-directed RNA polymerase
Re03.g09330 subunit 5184 15434 25684
Deoxyhypusine hydroxylase
Re03.g09340 EC=1.14.99.29 5185 15435 25685
NADH-ubiquinone oxidoreductase
Re03.g09350 18 kDa subunit, putative 5186 15436 25686 31496 32986
Re03.g09360 Putative uncharacterized protein 5187 15437 25687
Histone acetyltransferase (Esa1 ),
Re03.g09370 putative 5188 15438 25688
Re03.g09380 Pre-mRNA-splicing factor ce l 5189 15439 25689
Re03.g09390 Putative uncharacterized protein 5190 15440 25690
Re03.g09400 Uncharacterized protein 5191 15441 25691
Re03.g09410 Uncharacterized protein 5192 15442 25692
Re03.g09420 Uncharacterized protein 5193 15443 25693
Re03.g09430 Putative uncharacterized protein 5194 15444 25694
Re03.g09440 Uncharacterized protein 5195 15445 25695 31497 32987
Re03.g09450 hypothetical protein 5196 15446 25696
Re03.g09460 RNA exonuclease 4 5197 15447 25697
Re03.g09470 Putative uncharacterized protein 5198 15448 25698
MRNA decapping hydrolase,
Re03.g09480 putative 5199 15449 25699
Ubiquitin C-terminal hydrolase L3
Re03.g09490 EC=3.1.2.15 5200 15450 25700
Re03.g09500 MT-A70 family 5201 15451 25701
Re03.g09510 hypothetical protein 5202 15452 25702
Re03.g09520 hypothetical protein 5203 15453 25703
Re03.g09530 Nucleoside-triphosphatase 5204 15454 25704
Re03.g09540 RNA binding protein Jsn1 , putative 5205 15455 25705
Re03.g09550 Signal transducer, putative 5206 15456 25706
Re03.g09560 Putative uncharacterized protein 5207 15457 25707
Cytoplasmic asparaginyl-tRNA
Re03.g09570 synthetase, putative 5208 15458 25708
Differentiation regulator (Nrd1 ),
Re03.g09580 putative 5209 15459 25709
Re03.g09590 Uncharacterized protein 5210 15460 25710
Re03.g09600 Uncharacterized protein 521 1 15461 2571 1
Re03.g09610 hypothetical protein 5212 15462 25712 Re03.g09620 hypothetical protein 5213 15463 25713
Re03.g09630 Uncharacterized protein 5214 15464 25714
Re03.g09640 Uncharacterized protein 5215 15465 25715
Siderochrome-iron transporter
Re03.g09650 (MirC), putative 5216 15466 25716
Re03.g09660 Cell division control protein 42 5217 15467 25717
Re03.g09670 Agmatinase, putative 5218 15468 25718 31498 32988
3-oxoacyl-[acyl-carrier-protein]
Re03.g09680 synthase 5219 15469 25719
SAGA complex component
Re03.g09690 (Sgf73), putative 5220 15470 25720
mRNA capping enzyme alpha
Re03.g09700 subunit, putative 5221 15471 25721
Re03.g09710 DNA Iigase EC=6.5.1.1 5222 15472 25722
Re03.g09720 Uncharacterized protein 5223 15473 25723
Eukaryotic translation initiation
Re03.g09730 factor 5 5224 15474 25724
Thiamine biosynthetic bifunctional
Re03.g09740 enzyme, putative 5225 15475 25725
Isochorismatase domain-containing
Re03.g09750 protein 5226 15476 25726
Re03.g09760 Uncharacterized protein 5227 15477 25727
GDSL Lipase/Acylhydrolase family
Re03.g09770 protein 5228 15478 25728
Re03.g09780 Uncharacterized protein 5229 15479 25729
Re03.g09790 Uncharacterized protein 5230 15480 25730 31499 32989
Re03.g09800 hypothetical protein 5231 15481 25731
Re03.g09810 Putative uncharacterized protein 5232 15482 25732
Re03.g09820 Uncharacterized protein 5233 15483 25733
Exosome complex endonuclease
2/ribosomal RNA processing
Re03.g09830 protein, putative 5234 15484 25734
Re03.g09840 P-type ATPase 5235 15485 25735
Re03.g09850 Putative uncharacterized protein 5236 15486 25736
Terminal deoxynucleotidyl
Re03.g09860 transferase, putative 5237 15487 25737
Re03.g09870 Pc13g03730 protein 5238 15488 25738
Re03.g09880 Putative uncharacterized protein 5239 15489 25739
Re03.g09890 Uncharacterized protein 5240 15490 25740 31500 32990
Re03.g09900 Uncharacterized protein 5241 15491 25741
Re03.g09910 Uncharacterized protein 5242 15492 25742
Re03.g09920 Putative uncharacterized protein 5243 15493 25743
Re03.g09930 Uncharacterized protein 5244 15494 25744 31501 32991
Guanyl-nucleotide exchange factor,
Re03.g09940 putative 5245 15495 25745
RING finger domain protein,
Re03.g09950 putative 5246 15496 25746
Mitochondrial inner membrane
Re03.g09960 nuclease Nuc1 , putative 5247 15497 25747 31502 32992 Re03.g09970 ZIP metal ion transporter, putative 5248 15498 25748
Re03.g09980 Putative uncharacterized protein 5249 15499 25749
Trafficking protein particle complex
Re03.g09990 subunit 2/Sedlin, putative 5250 15500 25750
Isochorismatase family hydrolase,
Re03.g10000 putative 5251 15501 25751
Re03.g10010 Nuclear distribution protein NudE 5252 15502 25752
Acetyl-CoA carboxylase, putative
Re03.g10020 EC=6.4.1.2 5253 15503 25753
Re03.g10030 Uncharacterized protein 5254 15504 25754
Re03.g10040 hypothetical protein 5255 15505 25755
Re03.g10050 RING finger membrane protein 5256 15506 25756
Re03.g10060 Putative uncharacterized protein 5257 15507 25757
Re03.g10070 Putative uncharacterized protein 5258 15508 25758 31503 32993
Re03.g10080 Protein bimA 5259 15509 25759
1 -acylglycerol-3-phosphate
Re03.g10090 acyltransferase (AtaAp), putative 5260 15510 25760 31504 32994
Glucan endo-1 ,3-beta-glucosidase,
Re03.g10100 putative 5261 1551 1 25761
4'-phosphopantetheinyl transferase
Re03.g101 10 NpgA/CfwA 5262 15512 25762
Re03.g10120 Pyridoxine 5263 15513 25763 31505 32995
Small subunit of nuclear cap-
Re03.g10130 binding protein complex 5264 15514 25764
Re03.g10140 Putative uncharacterized protein 5265 15515 25765
Re03.g10150 Uncharacterized protein 5266 15516 25766
Re03.g10160 Peptidyl-prolyl cis/trans isomerase 5267 15517 25767
DNA-directed RNA polymerase
Re03.g10170 subunit 5268 15518 25768
Re03.g10180 50S ribosomal protein L14 5269 15519 25769 31506 32996
Histone-lysine N-methyltransferase
Re03.g10190 set9 5270 15520 25770
Re03.g10200 Putative uncharacterized protein 5271 15521 25771
Re03.g10210 Uncharacterized protein 5272 15522 25772 31507 32997
Re03.g10220 hypothetical protein 5273 15523 25773 31508 32998
Re03.g10230 Multicopper oxidase, putative 5274 15524 25774 31509 32999
Low-affinity glucose transporter
Re03.g 10240 HXT3 5275 15525 25775
ATP-dependent RNA helicase
Re03.g10250 Mrh4, putative 5276 15526 25776 31510 33000
GTP binding protein (Bud4),
Re03.g10260 putative 5277 15527 25777
tRNA pseudouridine synthase,
Re03.g10270 putative 5278 15528 25778
Transcription factor TFIIE complex
Re03.g10280 alpha subunit, putative 5279 15529 25779
Ubiquitin C-terminal hydrolase,
Re03.g10290 putative Fragment 5280 15530 25780
Acetyltransferase,
Re03.g10300 CysE/LacA/LpxA/NodL family 5281 15531 25781 Prenyl cysteine carboxyl
Re03.g10310 methyltransferase Ste14 5282 15532 25782
Peroxisomal membrane protein
Re03.g10320 Pex17, putative 5283 15533 25783 3151 1 33001
Re03.g10330 Integral membrane protein 5284 15534 25784
Re03.g10340 WD repeat protein 5285 15535 25785
Re03.g10350 Diacylglycerol O-acyltransferase 5286 15536 25786
Re03.g10360 Uncharacterized protein 5287 15537 25787
Re03.g10370 hypothetical protein 5288 15538 25788
Re03.g10380 Glutathione S-transferase, putative 5289 15539 25789 31512 33002
Orotidine 5'-phosphate
Re03.g10390 decarboxylase PyrG 5290 15540 25790
MFS allantoate transporter,
Re03.g10400 putative 5291 15541 25791
Re03.g10410 Putative uncharacterized protein 5292 15542 25792
Re03.g 10420 hypothetical protein 5293 15543 25793
Re03.g10430 Uncharacterized protein 5294 15544 25794
U3 small nucleolar
Re03.g 10440 ribonucleoprotein IMP3 5295 15545 25795
Zinc-binding oxidoreductase ToxD,
Re03.g 10450 putative 5296 15546 25796
Re03.g 10460 DnaJ domain protein, putative 5297 15547 25797 31513 33003
Re03.g10470 Putative uncharacterized protein 5298 15548 25798
Re03.g10480 Malic enzyme 5299 15549 25799
Re03.g10490 Uncharacterized protein 5300 15550 25800
Re03.g10500 Uncharacterized protein 5301 15551 25801
Re03.g10510 C6 transcription factor, putative 5302 15552 25802
Re03.g10520 MFS transporter, putative 5303 15553 25803
Re03.g10530 Putative uncharacterized protein 5304 15554 25804 31514 33004
MFS nicotinic acid transporter
Re03.g 10540 Tna1 5305 15555 25805
Re03.g10550 Uncharacterized protein 5306 15556 25806
Short-chain dehydrogenase,
Re03.g10560 putative 5307 15557 25807
MAK1 -like monooxygenase,
Re03.g10570 putative 5308 15558 25808
Re03.g10580 Maltose permease, putative 5309 15559 25809
Re03.g10590 Putative uncharacterized protein 5310 15560 25810
Re03.g10600 Uncharacterized protein 531 1 15561 2581 1
Tubulin-specific chaperone Rbl2,
Re03.g10610 putative 5312 15562 25812
Re03.g10620 Predicted protein 5313 15563 25813
Re03.g10630 Flotillin domain protein 5314 15564 25814
Putative uncharacterized protein
Re03.g 10640 An02g1 1260 Precursor 5315 15565 25815 31515 33005
RNA polymerase II transcription
factor Sill (Elongin) subunit A,
Re03.g10650 putative 5316 15566 25816
Re03.g10660 Uncharacterized protein 5317 15567 25817 Re03.g10670 Uncharacterized protein 5318 15568 25818
Re03.g10680 hypothetical protein 5319 15569 25819
Re03.g10690 Amino acid transporter, putative 5320 15570 25820
Re03.g10700 hypothetical protein 5321 15571 25821
Re03.g10710 Uncharacterized protein 5322 15572 25822
Re03.g10720 hypothetical protein 5323 15573 25823
Re03.g10730 hypothetical protein 5324 15574 25824
Re03.g10740 hypothetical protein 5325 15575 25825 31516 33006
Re03.g10750 C6 finger domain protein, putative 5326 15576 25826
Re03.g10760 hypothetical protein 5327 15577 25827
Short chain
dehydrogenase/reductase family
Re03.g10770 protein 5328 15578 25828
Re03.g10780 Involucrin repeat protein 5329 15579 25829
CorA family metal ion transporter,
Re03.g10790 putative 5330 15580 25830
Phospholipid metabolism enzyme
Re03.g10800 regulator, putative 5331 15581 25831
Re03.g10810 hypothetical protein 5332 15582 25832
Re03.g10820 Putative uncharacterized protein 5333 15583 25833
Re03.g10830 Uncharacterized protein 5334 15584 25834
Re03.g10840 Putative uncharacterized protein 5335 15585 25835
Re03.g10850 Similar to An12g02300 5336 15586 25836
Re03.g10860 Putative uncharacterized protein 5337 15587 25837 31517 33007
Re03.g10870 Glucosylceramidase 5338 15588 25838 31518 33008
Re03.g10880 Ribosomal protein L19 5339 15589 25839
Re03.g10890 Translational activator, putative 5340 15590 25840
ATP dependent RNA helicase,
Re03.g10900 putative 5341 15591 25841
Re03.g10910 hypothetical protein 5342 15592 25842
Re03.g10920 hypothetical protein 5343 15593 25843
Re03.g10930 hypothetical protein 5344 15594 25844
Re03.g10940 APSES transcription factor StuA 5345 15595 25845
Re03.g10950 Uncharacterized protein 5346 15596 25846
Putative pyruvate carboxylase
Re03.g10960 protein 5347 15597 25847
Re03.g10970 O-methyltransferase, putative 5348 15598 25848
Re03.g10980 Uncharacterized protein 5349 15599 25849
Patatin-like serine hydrolase,
Re03.g10990 putative 5350 15600 25850
Competence/damage-inducible
Re03.g1 1000 CinA family protein, putative 5351 15601 25851
Cytosolic
Re03.g1 1010 hydroxymethyltransferase, putative 5352 15602 25852 31519 33009
Re03.g1 1020 Uncharacterized protein 5353 15603 25853 31520 33010
Re03.g1 1030 hypothetical protein 5354 15604 25854
Integral membrane protein,
Re03.g1 1040 putative 5355 15605 25855
Re03.g1 1050 Uncharacterized protein 5356 15606 25856 Re03.g1 1060 Acyl-CoA synthetase, putative 5357 15607 25857
Ras small monomeric GTPase
Re03.g1 1070 RasB 5358 15608 25858
Re03.g1 1080 AMP-binding enzyme, putative 5359 15609 25859
Re03.g1 1090 BolA domain protein 5360 15610 25860
Re03.g1 1 100 SNARE domain protein 5361 1561 1 25861
Re03.g1 1 1 10 C6 transcription factor 5362 15612 25862
Nicotinate
Re03.g1 1 120 phosphoribosyltransferase 5363 15613 25863
PHD finger domain protein,
Re03.g1 1 130 putative 5364 15614 25864
DNA-directed RNA polymerase III
Re03.g1 1 140 subunit Rpc34 5365 15615 25865
Re03.g1 1 150 Heat shock protein (Sti1 ), putative 5366 15616 25866
Re03.g1 1 160 Nuclear migration protein, putative 5367 15617 25867
Re03.g1 1 170 Putative uncharacterized protein 5368 15618 25868 31521 3301 1
Re03.g1 1 180 Uncharacterized protein 5369 15619 25869
Re03.g1 1 190 hypothetical protein 5370 15620 25870
Re03.g1 1200 Putative uncharacterized protein 5371 15621 25871
MRNA splicing factor RNA helicase
Re03.g1 1210 (Cdc28), putative 5372 15622 25872
Re03.g1 1220 Protein kinase, putative 5373 15623 25873
Re03.g1 1230 hypothetical protein 5374 15624 25874
Re03.g1 1240 hypothetical protein 5375 15625 25875
Nonribosomal siderophore peptide
Re03.g1 1250 synthase, putative 5376 15626 25876
Re03.g1 1260 L-ornithine N5-oxygenase SidA 5377 15627 25877
Re03.g1 1270 Palmitoyltransferase EC=2.3.1.225 5378 15628 25878
Cyclin-dependent protein kinase
complex component (Pcl8),
Re03.g1 1280 putative 5379 15629 25879
Re03.g1 1290 hypothetical protein 5380 15630 25880 31522 33012
Re03.g1 1300 hypothetical protein 5381 15631 25881
Re03.g1 1310 Putative uncharacterized protein 5382 15632 25882
Re03.g1 1320 Vacuolar H+/Ca2+ exchanger 5383 15633 25883
Cystathionine beta-synthase,
Re03.g1 1330 putative 5384 15634 25884
Short chain
Re03.g1 1340 dehydrogenase/reductase, putative 5385 15635 25885
Re03.g1 1350 Uncharacterized protein 5386 15636 25886
Beta-1 ,6-glucan boisynthesis
Re03.g1 1360 protein (Knh1 ), putative 5387 15637 25887
Re03.g1 1370 Putative uncharacterized protein 5388 15638 25888
Mitochondrial inner membrane
Re03.g1 1380 protease atp23 EC=3.4.24.- 5389 15639 25889
Serine/threonine protein kinase
Re03.g1 1390 (Ark1 ), putative 5390 15640 25890
TOR signaling pathway protein
Re03.g1 1400 TipA, putative 5391 15641 25891 Ubiquinol-cytochrome C
Re03.g11410 chaperone, putative 5392 15642 25892
Leukotriene A-4 hydrolase
Re03.g11420 homolog EC=3.3.2.6 5393 15643 25893
Probable Xaa-Pro aminopeptidase
Re03.g11430 pepP EC=3.4.11.9 5394 15644 25894
Re03.g11440 Putative uncharacterized protein 5395 15645 25895
Re03.g11450 hypothetical protein 5396 15646 25896
Re03.g11460 5-oxo-L-prolinase, putative 5397 15647 25897
RNA polymerase II transcriptional
Re03.g11470 coactivator, putative 5398 15648 25898
Re03.g11480 PX domain protein 5399 15649 25899
Re03.g11490 Thioesterase family protein 5400 15650 25900
Re03.g11500 DDHD domain protein 5401 15651 25901
Actin-bundling protein Sac6,
Re03.g11510 putative 5402 15652 25902
Re03.g11520 Uncharacterized protein 5403 15653 25903
Re03.g11530 O-acyltransferase 5404 15654 25904
Re03.g 11540 O-acyltransferase 5405 15655 25905
Putative RNA binding protein SwoK
Re03.g11550 (Eurofung) 5406 15656 25906 31523 33013
Re03.g11560 Pc13g05530 protein 5407 15657 25907
Re03.g11570 60S ribosomal protein L18 5408 15658 25908
Gamma-glutamyl phosphate
Re03.g11580 reductase EC=1.2.1.41 5409 15659 25909
COP9 signalosome complex
Re03.g11590 subunit 3 5410 15660 25910
Re03.g11600 Uncharacterized protein 5411 15661 25911
Re03.g11610 Putative uncharacterized protein 5412 15662 25912
Re03.g11620 Putative uncharacterized protein 5413 15663 25913
Re03.g11630 Putative uncharacterized protein 5414 15664 25914
Re03.g11640 Putative uncharacterized protein 5415 15665 25915
Re03.g11650 Putative uncharacterized protein 5416 15666 25916 31524 33014
Re03.g11660 Putative uncharacterized protein 5417 15667 25917
Re03.g11670 Uncharacterized protein 5418 15668 25918
Re03.g11680 Putative uncharacterized protein 5419 15669 25919
Re03.g11690 hypothetical protein 5420 15670 25920
Re03.g11700 hypothetical protein 5421 15671 25921
Re03.g11710 hypothetical protein 5422 15672 25922
Re03.g11720 hypothetical protein 5423 15673 25923
Re03.g11730 Putative uncharacterized protein 5424 15674 25924
Re03.g11740 Uncharacterized protein 5425 15675 25925
Re03.g11750 hypothetical protein 5426 15676 25926
Ubiquitin carboxyl-terminal
Re03.g11760 hydrolase EC=3.4.19.12 5427 15677 25927
Replication protein A 70 kDa DNA-
Re03.g11770 binding subunit 5428 15678 25928
Re03.g11780 Uncharacterized protein 5429 15679 25929
Re03.g11790 Nuclear division Rft1 protein, 5430 15680 25930 putative
Re03.g1 1800 hypothetical protein 5431 15681 25931
Oligosaccharyl transferase subunit
Re03.g1 1810 (Gamma) 5432 15682 25932 31525 33015
Re03.g1 1820 Uncharacterized protein 5433 15683 25933
Re03.g1 1830 hypothetical protein 5434 15684 25934
Re03.g1 1840 Uncharacterized protein 5435 15685 25935
Ubiquitin activating E1 enzyme-like
Re03.g1 1850 protein 5436 15686 25936
Deoxycytidylate deaminase,
Re03.g1 1860 putative 5437 15687 25937
Imidazole glycerol phosphate
Re03.g1 1870 synthase subunit hisF EC=4.1.3.- 5438 15688 25938
Re03.g1 1880 Uncharacterized protein 5439 15689 25939
Re03.g1 1890 Yippee family protein 5440 15690 25940
Re03.g1 1900 Putative uncharacterized protein 5441 15691 25941
Re03.g1 1910 Uncharacterized protein 5442 15692 25942
Re03.g1 1920 DUF907 domain protein 5443 15693 25943 31526 33016
Re03.g1 1930 hypothetical protein 5444 15694 25944
Re03.g1 1940 Uncharacterized protein 5445 15695 25945
Chromatin remodeling and histone
acetyltransferase complexes
Re03.g1 1950 subunit 5446 15696 25946
Re03.g1 1960 Uncharacterized protein 5447 15697 25947
Re03.g1 1970 Uracil DNA N-glycosylase, putative 5448 15698 25948
Protein disulfide isomerase Pdi1 ,
Re03.g1 1980 putative 5449 15699 25949 31527 33017
Re03.g1 1990 Autophagy protein Atg22, putative 5450 15700 25950
Re03.g12000 hypothetical protein 5451 15701 25951
RNA polymerase II
holoenzyme/mediator complex
Re03.g12010 component Rgr1 , putative 5452 15702 25952
Heterogeneous nuclear
Re03.g12020 ribonucleoprotein HRP1 5453 15703 25953
Re03.g12030 TBC domain 5454 15704 25954
Dimethyladenosine transferase,
Re03.g12040 putative EC=2.1.1.- 5455 15705 25955
mRNA splicing factor (Prp1/Zer1 ),
Re03.g12050 putative 5456 15706 25956
Transcriptional co-activator
Re03.g12060 (Hfi1/Ada1 ), putative 5457 15707 25957
Re03.g12070 Putative uncharacterized protein 5458 15708 25958
Re03.g12080 Uncharacterized protein 5459 15709 25959
NAD dependent glutamate
Re03.g12090 dehydrogenase, putative 5460 15710 25960
Re03.g12100 hypothetical protein 5461 1571 1 25961
Re03.g121 10 Transposon, putative 5462 15712 25962
Re03.g12120 hypothetical protein 5463 15713 25963
Re03.g12130 Uncharacterized protein 5464 15714 25964 Re03.g12140 Putative uncharacterized protein 5465 15715 25965
PHD finger and JmjC domain
Re03.g12150 protein, putative 5466 15716 25966
Pre-mRNA branch site protein p14,
Re03.g12160 putative 5467 15717 25967
Re03.g12170 Putative uncharacterized protein 5468 15718 25968 31528 33018
Re03.g12180 Uncharacterized protein 5469 15719 25969
Re03.g12190 Uncharacterized protein 5470 15720 25970
Carnitinyl-CoA dehydratase,
Re03.g12200 putative 5471 15721 25971
Re03.g12210 Hexokinase Kxk, putative 5472 15722 25972
Re03.g12220 Putative uncharacterized protein 5473 15723 25973
Re03.g12230 Uncharacterized protein 5474 15724 25974
Re03.g 12240 Putative uncharacterized protein 5475 15725 25975 31529 33019
Re03.g12250 Ammonium transporter MeaA 5476 15726 25976
Re03.g12260 hypothetical protein 5477 15727 25977
Calcium/mangenease P-type
Re03.g12270 ATPase, putative 5478 15728 25978
Double-strand-break repair protein
Re03.g12280 rad21 5479 15729 25979
Re03.g12290 Putative uncharacterized protein 5480 15730 25980
Re03.g12300 Uncharacterized protein Fragment 5481 15731 25981
Re03.g12310 Riboflavin kinase, putative 5482 15732 25982
Re03.g12320 Putative uncharacterized protein 5483 15733 25983
Transcription activator of
Re03.g12330 gluconeogenesis acuK 5484 15734 25984
Re03.g12340 hypothetical protein 5485 15735 25985
Re03.g12350 IdgA domain protein 5486 15736 25986
Oligosaccharyl transferase subunit
Re03.g12360 (Alpha), putative 5487 15737 25987 31530 33020
Vacuolar transporter chaperone
Re03.g12370 (Vtc4), putative 5488 15738 25988
DNA replication licensing factor
Re03.g12380 Mcm4, putative 5489 15739 25989
Re03.g12390 Uncharacterized protein 5490 15740 25990
Arginine N-methyltransferase
Re03.g12400 (Rmt2), putative 5491 15741 25991
Re03.g12410 Putative uncharacterized protein 5492 15742 25992 31531 33021
Re03.g 12420 Prohibitin, putative 5493 15743 25993
Polyadenylation factor subunit
Re03.g12430 CstF64, putative 5494 15744 25994
C-5 cytosine-specific DNA
Re03.g 12440 methylase, putative 5495 15745 25995
NADH-ubiquinone dehydrogenase
Re03.g 12450 24 kDa subunit, putative 5496 15746 25996
Re03.g 12460 Putative uncharacterized protein 5497 15747 25997
Re03.g12470 Adenosine deaminase 5498 15748 25998
Re03.g12480 Epoxide hydrolase 5499 15749 25999
Re03.g12490 Protein SUA5 5500 15750 26000 Re03.g12500 Putative uncharacterized protein 5501 15751 26001
Re03.g12510 Protein dopey 5502 15752 26002
Re03.g12520 Putative uncharacterized protein 5503 15753 26003 31532 33022
Re03.g12530 HIT finger domain protein, putative 5504 15754 26004
Glycerol:H+ symporter (Gup1 ),
Re03.g 12540 putative 5505 15755 26005
Re03.g12550 Cytochrome P450, putative 5506 15756 26006 31533 33023
Phosphoethanolamine N-
Re03.g12560 methyltransferase, putative 5507 15757 26007
Re03.g12570 Alternative oxidase EC=1 5508 15758 26008
Re03.g12580 Putative uncharacterized protein 5509 15759 26009
Re03.g12590 Similar to An14g04490 5510 15760 26010 31534 33024
GNAT family acetyltransferase,
Re03.g12600 putative 551 1 15761 2601 1
Re03.g12610 Uncharacterized protein 5512 15762 26012
Re03.g12620 hypothetical protein 5513 15763 26013 31535 33025
ACN9 family domain containing
Re03.g12630 protein, putative 5514 15764 26014 31536 33026
Re03.g 12640 Putative uncharacterized protein 5515 15765 26015
Re03.g12650 hypothetical protein 5516 15766 26016
Re03.g12660 Putative uncharacterized protein 5517 15767 26017
Re03.g12670 Putative uncharacterized protein 5518 15768 26018
Re03.g12680 Putative uncharacterized protein 5519 15769 26019
Re03.g12690 Putative uncharacterized protein 5520 15770 26020
MFS monosaccharide transporter,
Re03.g12700 putative 5521 15771 26021
ER membrane protein (Pkr1 ),
Re03.g12710 putative 5522 15772 26022
Predicted: nicotinamide
phosphoribosyltransferase isoform
Re03.g12720 X2 5523 15773 26023
Re03.g12730 Uncharacterized protein 5524 15774 26024
Anaphase-promoting complex
Re03.g12740 subunit ApcB, putative 5525 15775 26025
Re03.g12750 Putative uncharacterized protein 5526 15776 26026
Re03.g12760 Putative uncharacterized protein 5527 15777 26027
Re03.g12770 hypothetical protein 5528 15778 26028
Re03.g12780 hypothetical protein 5529 15779 26029
Putative alcohol dehydrogenase
Re03.g12790 protein 5530 15780 26030
ATP-dependent RNA helicase
Re03.g12800 (Hrh1 ), putative 5531 15781 26031
Mitochondrial carrier protein,
Re03.g12810 putative 5532 15782 26032
Re03.g12820 F-box protein (Pof7), putative 5533 15783 26033
Re03.g12830 Transcription factor RfeD, putative 5534 15784 26034
Re03.g12840 Uncharacterized protein 5535 15785 26035 31537 33027
Re03.g12850 hypothetical protein 5536 15786 26036
Re03.g12860 Endo-1 ,4-beta-xylanase 5537 15787 26037 EC=3.2.1.8
Re03.g12870 Putative uncharacterized protein 5538 15788 26038
Re03.g12880 Uncharacterized protein 5539 15789 26039 31538 33028
Glucose-methanol-choline (Gmc)
Re03.g12890 oxidoreductase, putative 5540 15790 26040
Protein kinase domain-containing
Re03.g12900 protein 5541 15791 26041
Taurine catabolism dioxygenase
Re03.g12910 TauD, TfdA family protein 5542 15792 26042
Re03.g12920 Uncharacterized protein 5543 15793 26043
Re03.g12930 hypothetical protein 5544 15794 26044
Re03.g12940 Uncharacterized protein 5545 15795 26045
Re03.g12950 Putative uncharacterized protein 5546 15796 26046 31539 33029
Re03.g12960 Extracellular serine-rich protein 5547 15797 26047 31540 33030
Re03.g12970 60S ribosomal protein L10 5548 15798 26048
Re03.g12980 Putative uncharacterized protein 5549 15799 26049
Re03.g12990 Uncharacterized protein 5550 15800 26050 31541 33031
Re03.g13000 Uncharacterized protein 5551 15801 26051
Re03.g13010 Putative uncharacterized protein 5552 15802 26052
Re03.g13020 RecQ family helicase MusN 5553 15803 26053
Re03.g13030 Putative uncharacterized protein 5554 15804 26054
Re03.g13040 Prolyl aminopeptidase EC=3.4.1 1.5 5555 15805 26055
Re03.g13050 Tyrosine decarboxylase, putative 5556 15806 26056
Re03.g13060 Kelch repeats protein, putative 5557 15807 26057
Re03.g13070 KH domain RNA binding protein 5558 15808 26058
Re03.g13080 Putative uncharacterized protein 5559 15809 26059
Re03.g13090 Putative uncharacterized protein 5560 15810 26060 31542 33032
Putative alpha-l-rhamnosidase
Re03.g13100 protein 5561 1581 1 26061 31543 33033
Re03.g13120 Uncharacterized protein 5562 15812 26062 31544 33034
Glutamine dependent NAD+
Re03.g13130 synthetase, putative 5563 15813 26063
Re03.g13140 Putative uncharacterized protein 5564 15814 26064
Re03.g13150 hypothetical protein 5565 15815 26065
Re03.g13160 hypothetical protein 5566 15816 26066
Re03.g13170 Uncharacterized protein 5567 15817 26067
Proteasome subunit beta type
Re03.g13180 EC=3.4.25.1 5568 15818 26068
Nuclear pore complex subunit
Re03.g13190 Nup159 5569 15819 26069
Re03.g13200 Uncharacterized protein 5570 15820 26070
Re03.g13210 hypothetical protein 5571 15821 26071
TAM domain methyltransferase,
Re03.g13220 putative 5572 15822 26072
Re03.g13230 hypothetical protein 5573 15823 26073
Re03.g 13240 Metallopeptidase Mip1 5574 15824 26074
Re03.g13250 Mitochondrial protein, putative 5575 15825 26075 31545 33035
Golgi reassembly stacking protein,
Re03.g13260 putative 5576 15826 26076 Re03.g13270 Methylase 5577 15827 26077
Transcription initiation factor TFIID,
Re03.g13280 subunit TAF1 5578 15828 26078
Serine/threonine protein kinase
Re03.g13290 cbkl 5579 15829 26079
Re03.g13300 FK506-binding protein 1A 5580 15830 26080
DNA damage repair protein Mus42,
Re03.g13310 putative 5581 15831 26081
Re03.g13320 NRPS-like enzyme 5582 15832 26082
Re03.g13330 Uncharacterized protein 5583 15833 26083
Re03.g13340 C6 transcription factor, putative 5584 15834 26084
Re03.g13350 C6 finger domain protein, putative 5585 15835 26085
Re03.g13360 hypothetical protein 5586 15836 26086
Re03.g13370 Uncharacterized protein 5587 15837 26087
Re03.g13380 tRNA methyltransferase, putative 5588 15838 26088
Re03.g13390 Assimilatory sulfite reductase 5589 15839 26089
Protein fmp52-1 , mitochondrial
Re03.g13400 Precursor 5590 15840 26090
Re03.g13410 Putative uncharacterized protein 5591 15841 26091
Re03.g 13420 Putative uncharacterized protein 5592 15842 26092
Proteasome subunit alpha type
Re03.g13430 EC=3.4.25.1 5593 15843 26093
Re03.g 13440 Pc12g08440 protein 5594 15844 26094
Putative uncharacterized protein
Re03.g 13450 An1 1 g06740 5595 15845 26095
Re03.g 13460 Uncharacterized protein 5596 15846 26096
U1 snRNP splicing complex
Re03.g13470 subunit (Luc7), putative 5597 15847 26097
GPI transamidase component
Re03.g13480 Gpi16, putative 5598 15848 26098 31546 33036
Re03.g13490 Uncharacterized protein 5599 15849 26099
Re03.g13500 Putative uncharacterized protein 5600 15850 26100
Re03.g13510 hypothetical protein 5601 15851 26101
Flavin-containing monooxygenase,
Re03.g13520 putative 5602 15852 26102
Re03.g13530 hypothetical protein 5603 15853 26103 31547 33037
Re03.g 13540 hypothetical protein 5604 15854 26104
Re03.g13550 Carboxyl esterase 5605 15855 26105 31548 33038
Nuclear membrane fusion protein
Re03.g13560 Kar5 5606 15856 26106
Re03.g13570 60S ribosomal protein L6, putative 5607 15857 26107 31549 33039
Re03.g13580 3'(2'),5'-bisphosphate nucleotidase 5608 15858 26108
Re03.g13590 VHS domain protein 5609 15859 26109
Re03.g13600 Uncharacterized protein 5610 15860 261 10
Re03.g13610 MFS multidrug transporter, putative 561 1 15861 261 1 1
Re03.g13620 Putative uncharacterized protein 5612 15862 261 12
Re03.g13630 Putative uncharacterized protein 5613 15863 261 13
Re03.g 13640 Ubiquitin-like protein ATG12 5614 15864 261 14
Re03.g13650 Ubiquitin-conjugating enzyme h 5615 15865 261 15 Re03.g13660 Uncharacterized protein 5616 15866 261 16
Re03.g13670 Putative uncharacterized protein 5617 15867 261 17
Re03.g13680 Predicted protein 5618 15868 261 18
Re03.g13690 hypothetical protein 5619 15869 261 19 31550 33040
3-methyl-2-oxobutanoate
Re03.g13700 hydroxymethyltransferase PanB 5620 15870 26120
Re03.g13710 Putative uncharacterized protein 5621 15871 26121
Protein kinase essential for the
Re03.g13720 initiation of DNA replication 5622 15872 26122
Metallopeptidase family M24,
Re03.g13730 putative 5623 15873 26123
Putative flavin-nucleotide-binding
Re03.g13740 protein 5624 15874 26124
SIR2 family histone deacetylase,
Re03.g13750 putative 5625 15875 26125 31551 33041
SNF2 family helicase/ATPase,
Re03.g13760 putative 5626 15876 26126
Re03.g13770 hypothetical protein 5627 15877 26127
Re03.g13780 Protein kinase, putative 5628 15878 26128
Re03.g13790 Glucan 1 ,3-beta-glucosidase D 5629 15879 26129
Re03.g13800 hypothetical protein 5630 15880 26130
Sensor histidine kinase/response
Re03.g13810 regulator, putative 5631 15881 26131
Re03.g13820 Putative uncharacterized protein 5632 15882 26132 31552 33042
Re03.g13830 hypothetical protein 5633 15883 26133
Re03.g13840 Putative uncharacterized protein 5634 15884 26134
Re03.g13850 hypothetical protein 5635 15885 26135
Re03.g13860 Putative uncharacterized protein 5636 15886 26136
Re03.g13870 Glutathione synthetase 5637 15887 26137
Re03.g13880 Putative uncharacterized protein 5638 15888 26138
Re03.g13890 WD repeat protein 5639 15889 26139
Re03.g13900 Autophagy protein Atg 13, putative 5640 15890 26140
BTB domain and ankyrin repeat
Re03.g13910 protein 5641 15891 26141
Re03.g13920 Putative uncharacterized protein 5642 15892 26142
Vacuolar sorting-associated protein
Re03.g13930 (Vps27), putative 5643 15893 26143
Ubiquitin C-terminal hydrolase,
Re03.g13940 putative 5644 15894 26144
Re03.g13950 Predicted protein 5645 15895 26145
Re03.g13960 Nucleoside transporter, putative 5646 15896 26146
RNA binding effector protein
Re03.g13970 Scp160, putative 5647 15897 26147
Re03.g13980 Uncharacterized protein 5648 15898 26148 31553 33043
Re03.g13990 Putative uncharacterized protein 5649 15899 26149
Re03.g14000 Cytochrome b5, putative 5650 15900 26150
Sexual development
Re03.g14010 serine/threonine kinase PakA 5651 15901 26151
Re03.g14020 Class E vacuolar protein-sorting 5652 15902 26152 machinery protein hsel
Re03.g14030 Putative uncharacterized protein 5653 15903 26153
PAB-dependent poly(A)-specific
Re03.g14040 ribonuclease subunit pan2 5654 15904 26154
Re03.g14050 Uncharacterized protein 5655 15905 26155
Elongation factor Tu GTP binding
Re03.g14060 domain protein 5656 15906 26156
Hsp70 chaperone BiP/Kar2,
Re03.g14070 putative 5657 15907 26157 31554 33044
Re03.g14080 DUF967 domain protein 5658 15908 26158
Re03.g14090 Uncharacterized protein 5659 15909 26159
Re03.g14100 Alcohol dehydrogenase, putative 5660 15910 26160
Re03.g141 10 hypothetical protein 5661 1591 1 26161 31555 33045
Re03.g14120 Putative uncharacterized protein 5662 15912 26162
Transposon-encoded proteins with
Re03.g14130 TYA 5663 15913 26163
Re03.g14140 Reverse transcriptase, putative 5664 15914 26164
Re03.g14150 Reverse transcriptase, putative 5665 15915 26165
Re03.g14160 Putative uncharacterized protein 5666 15916 26166
Re03.g14170 Putative uncharacterized protein 5667 15917 26167
Re03.g14180 Reverse transcriptase, putative 5668 15918 26168
Re03.g14190 Putative uncharacterized protein 5669 15919 26169
Re03.g14200 hypothetical protein 5670 15920 26170
Re03.g14210 Predicted protein 5671 15921 26171
Gag/polymerase/env polyprotein,
Re03.g14220 putative 5672 15922 26172
Re03.g14230 Putative uncharacterized protein 5673 15923 26173
Re03.g 14240 Uncharacterized protein 5674 15924 26174
Re03.g14250 Phosphotransferase family protein 5675 15925 26175
Re03.g14260 Reverse transcriptase, putative 5676 15926 26176
Glycoside hydrolase family 18
Re03.g14270 protein Fragment 5677 15927 26177 31556 33046
Re03.g14280 hypothetical protein 5678 15928 26178
Re03.g14290 Uncharacterized protein 5679 15929 26179 31557 33047
Re03.g14300 hypothetical protein 5680 15930 26180
Re03.g14310 Putative uncharacterized protein 5681 15931 26181
Re03.g14320 Transposase 5682 15932 26182
Whole genome shotgun sequence
assembly, scaffold 69, strain
Re03.g14330 Mel28 5683 15933 26183
Re03.g14340 Uncharacterized protein 5684 15934 26184 31558 33048
Re03.g14350 Transposase 5685 15935 26185
Re03.g14360 Uncharacterized protein 5686 15936 26186
Re03.g14370 Uncharacterized protein 5687 15937 26187 31559 33049
Re03.g14380 Short-chain dehydrogenase 5688 15938 26188
Re03.g14390 FAD binding domain protein 5689 15939 26189
Re03.g14400 RNAse III, putative 5690 15940 26190
Re03.g14410 Glycosyl hydrolase, putative 5691 15941 26191 31560 33050
Re03.g 14420 hypothetical protein 5692 15942 26192 31561 33051 Glycoside hydrolase family 78
Re03.g14430 protein 5693 15943 26193 31562 33052
Re03.g 14440 Amino acid transporter 5694 15944 26194
Re03.g 14450 hypothetical protein 5695 15945 26195
Re03.g 14460 Putative uncharacterized protein 5696 15946 26196
Similarity to hypothetical protein
Re03.g14470 encoded by An02g09280 5697 15947 26197
Re03.g14480 Ran exchange factor Prp20/Pim1 5698 15948 26198
Aspartate aminotransferase
Re03.g14490 EC=2.6.1.1 5699 15949 26199
Putative FAD linked oxidase
Re03.g14500 domain protein 5700 15950 26200
Re03.g14510 Uncharacterized protein 5701 15951 26201
Polyketide synthase modules and
Re03.g14520 related proteins 5702 15952 26202
Re03.g14530 Uncharacterized protein 5703 15953 26203 31563 33053
Re03.g 14540 Uncharacterized protein 5704 15954 26204 31564 33054
Re03.g14550 Putative uncharacterized protein 5705 15955 26205
Re03.g14560 Putative uncharacterized protein 5706 15956 26206
U6 snRNA phosphodiesterase
Re03.g14570 EC=3.1.4.- 5707 15957 26207
Re03.g14580 Putative uncharacterized protein 5708 15958 26208
Re03.g14590 Uncharacterized protein 5709 15959 26209
Re03.g14600 hypothetical protein 5710 15960 26210
Re03.g14610 Putative uncharacterized protein 571 1 15961 2621 1
Re03.g14620 Putative uncharacterized protein 5712 15962 26212
Peroxisomal membrane protein
Re03.g14630 (Pex13), putative 5713 15963 26213 31565 33055
Re03.g 14640 Oxidoreductin 5714 15964 26214 31566 33056
Re03.g14650 Uncharacterized protein 5715 15965 26215
Re03.g14660 Predicted protein 5716 15966 26216
Re03.g14670 Uncharacterized protein 5717 15967 26217 31567 33057
Re03.g14680 DUF455 domain protein 5718 15968 26218
Re03.g14690 Cytochrome P450 5719 15969 26219
Re03.g14700 Autophagy protein Apg6, putative 5720 15970 26220
Myb-like DNA-binding domain
Re03.g14710 protein 5721 15971 26221
Cysteine synthase, putative
Re03.g14720 EC=2.5.1.47 5722 15972 26222
Re03.g14730 COG1565 domain protein 5723 15973 26223
Re03.g14740 Uncharacterized protein 5724 15974 26224 31568 33058
Re03.g14750 Putative uncharacterized protein 5725 15975 26225
Re03.g14760 Uncharacterized protein 5726 15976 26226
Re03.g14770 hypothetical protein 5727 15977 26227
Re03.g14780 Putative uncharacterized protein 5728 15978 26228
Major facilitator superfamily
Re03.g14790 transporter 5729 15979 26229
Re03.g14800 Choline transporter Hnm1 , putative 5730 15980 26230
Re03.g14810 Uncharacterized protein 5731 15981 26231 Aspartic protease pepl
Re03.g14820 EC=3.4.23.18 Precursor 5732 15982 26232 31569 33059
Nuclease S1 EC=3.1.30.1
Re03.g14830 Precursor 5733 15983 26233 31570 33060
Re03.g14840 Uncharacterized protein 5734 15984 26234 31571 33061
Re03.g14850 Uncharacterized protein 5735 15985 26235
Re03.g14860 GABA permease, putative 5736 15986 26236
Re03.g14870 Uncharacterized protein 5737 15987 26237
Re03.g14880 Uncharacterized protein 5738 15988 26238
Re03.g14890 hypothetical protein 5739 15989 26239
Re03.g14900 MFS transporter, putative 5740 15990 26240
Re03.g14910 Secretory lipase, putative 5741 15991 26241 31572 33062
Re03.g14920 HHE domain protein 5742 15992 26242
Re03.g14930 Uncharacterized protein 5743 15993 26243
Re03.g14940 hypothetical protein 5744 15994 26244
C4-dicarboxylate transporter/malic
Re03.g14950 acid transport protein, putative 5745 15995 26245
Re03.g14960 MFS transporter, putative 5746 15996 26246
Re03.g14970 Putative uncharacterized protein 5747 15997 26247
Re03.g14980 Uncharacterized protein 5748 15998 26248
Re03.g14990 Uncharacterized protein 5749 15999 26249
Pre-mRNA splicing helicase,
Re03.g15000 putative 5750 16000 26250
DNA mismatch repair protein
Re03.g15010 Msh1 , putative 5751 16001 26251
Re03.g15020 Ureidoglycolate hydrolase, putative 5752 16002 26252
Re03.g15030 Aldo-keto reductase 5753 16003 26253
Re03.g 15040 hypothetical protein 5754 16004 26254
Re03.g15050 Uncharacterized protein 5755 16005 26255
Re03.g15060 hypothetical protein 5756 16006 26256
Re03.g15070 Peptide transporter MTD1 5757 16007 26257
Re03.g15080 NmrA family protein 5758 16008 26258 31573 33063
Re03.g15090 Putative uncharacterized protein 5759 16009 26259
Phosphoglycerate mutase family
Re03.g15100 protein, putative 5760 16010 26260 31574 33064
Sulfatase domain-containing
Re03.g151 10 protein 5761 1601 1 26261 31575 33065
Re03.g15120 Predicted protein 5762 16012 26262
Re03.g15130 Beta-1 ,3-glucanosyltransferase 5763 16013 26263 31576 33066
Re03.g15140 C6 finger domain protein, putative 5764 16014 26264
Re03.g15150 hypothetical protein 5765 16015 26265
Re03.g15160 Predicted protein 5766 16016 26266
Re03.g15170 Putative uncharacterized protein 5767 16017 26267 31577 33067
Re03.g15180 Uncharacterized protein 5768 16018 26268
Re03.g15190 Uncharacterized protein 5769 16019 26269
Re03.g15200 Uncharacterized protein 5770 16020 26270
Re03.g15210 Putative uncharacterized protein 5771 16021 26271
Oxidoreductase, short-chain
Re03.g 15220 dehydrogenase/reductase family 5772 16022 26272 Re03.g15230 Putative uncharacterized protein 5773 16023 26273
Polygalacturonase (Pectinase),
Re03.g 15240 putative 5774 16024 26274 31578 33068
Re03.g 15250 Uncharacterized protein 5775 16025 26275 31579 33069
Re03.g 15260 Putative uncharacterized protein 5776 16026 26276
Re03.g15270 Zinc-binding oxidoreductase 5777 16027 26277
2-deoxy-D-gluconate 3-
Re03.g15280 dehydrogenase 5778 16028 26278 31580 33070
Re03.g15290 Uncharacterized protein 5779 16029 26279
Re03.g15300 hypothetical protein 5780 16030 26280
Re03.g15310 Putative cyclase 5781 16031 26281
Re03.g15320 Uncharacterized protein 5782 16032 26282
Pheromone-regulated membrane
Re03.g15330 protein, putative 5783 16033 26283
Re03.g 15340 Uncharacterized protein 5784 16034 26284 31581 33071
Re03.g15350 Uncharacterized protein 5785 16035 26285 31582 33072
Re03.g15360 Uncharacterized protein 5786 16036 26286
Re03.g15370 L-lysine 2,3-aminomutase, putative 5787 16037 26287
Re03.g15380 Predicted protein 5788 16038 26288
Re03.g15390 Putative uncharacterized protein 5789 16039 26289
NADPH-dependent FMN reductase
Re03.g 15400 Lot6, putative 5790 16040 26290
Re03.g15410 Uncharacterized protein 5791 16041 26291
Re03.g 15420 Putative uncharacterized protein 5792 16042 26292
Cytochrome P450
Re03.g 15430 monooxygenase, putative 5793 16043 26293 31583 33073
Monocarboxylate permease,
Re03.g 15440 putative 5794 16044 26294
Re03.g 15450 Uncharacterized protein 5795 16045 26295
Re03.g 15460 C6 transcription factor, putative 5796 16046 26296
Re03.g 15470 hypothetical protein 5797 16047 26297
Re03.g 15480 Choline dehydrogenase 5798 16048 26298
Re03.g 15490 Putative uncharacterized protein 5799 16049 26299
Re03.g15500 Cellobiohydrolase II EC=3.2.1.91 5800 16050 26300 31584 33074
Re03.g15510 Cytochrome P450, putative 5801 16051 26301
Re03.g 15520 Uncharacterized protein 5802 16052 26302 31585 33075
Dihydrodipicolinate synthase-like
Re03.g15530 protein 5803 16053 26303
Re03.g 15540 ABC transporter 5804 16054 26304
Mandelate racemase/muconate
Re03.g 15550 lactonizing enzyme family protein 5805 16055 26305
2-deoxy-D-gluconate 3-
Re03.g 15560 dehydrogenase, putative 5806 16056 26306
Re03.g15570 Uncharacterized protein 5807 16057 26307
Re03.g15580 Putative uncharacterized protein 5808 16058 26308
Re03.g15590 Putative uncharacterized protein 5809 16059 26309
Re03.g15600 Uncharacterized protein 5810 16060 26310
Re03.g15610 hypothetical protein 581 1 16061 2631 1
Re03.g 15620 hypothetical protein 5812 16062 26312 Glucose-methanol-choline
Re03.g15630 oxidoreductase 5813 16063 26313
Re03.g 15640 Catalase 5814 16064 26314
Re03.g 15650 Antigenic cell wall protein 5815 16065 26315 31586 33076
Re03.g 15660 Putative uncharacterized protein 5816 16066 26316
Re03.g15670 hypothetical protein 5817 16067 26317
Re03.g15680 Mrspl 5818 16068 26318 31587 33077
Re03.g15690 Putative uncharacterized protein 5819 16069 26319 31588 33078
Re03.g15700 Uncharacterized protein 5820 16070 26320
Re03.g15710 Oxalate decarboxylase oxdC 5821 16071 26321
Re03.g15720 C6 transcription factor, putative 5822 16072 26322
Re03.g15730 Putative uncharacterized protein 5823 16073 26323 31589 33079
Re03.g 15740 Uncharacterized protein 5824 16074 26324
Re03.g15750 hypothetical protein 5825 16075 26325 31590 33080
Putative multidrug resistance
Re03.g15760 protein fnxl protein 5826 16076 26326
Putative uncharacterized protein
Re03.g15770 An02g 12940 5827 16077 26327
Re03.g15780 Predicted protein 5828 16078 26328
Re03.g15790 hypothetical protein 5829 16079 26329
Re03.g15800 hypothetical protein 5830 16080 26330 31591 33081
Re03.g15810 Beta-hexosaminidase EC=3.2.1.52 5831 16081 26331 31592 33082
Peroxisomal targeting receptor
Re03.g15820 pex5, putative 5832 16082 26332
Re03.g15830 Nucleic acid-binding protein 5833 16083 26333
Re03.g 15840 C6 transcription factor, putative 5834 16084 26334
RNA interference and gene
Re03.g15850 silencing protein (Qde2), putative 5835 16085 26335
Re03.g15860 Putative uncharacterized protein 5836 16086 26336
Re03.g15870 RNA polymerase II subunit 7 5837 16087 26337
Re03.g15880 Uncharacterized protein 5838 16088 26338
Re03.g15890 ATP synthase subunit alpha 5839 16089 26339 31593 33083
Methylenetetrahydrofolate
Re03.g15900 dehydrogenase 5840 16090 26340
Re03.g15910 Putative uncharacterized protein 5841 16091 26341
Re03.g15920 DUF850 domain-containing protein 5842 16092 26342
Re03.g15930 Uncharacterized protein 5843 16093 26343 31594 33084
Re03.g 15940 DNA repair/transcription protein 5844 16094 26344
Re03.g15950 Uncharacterized protein 5845 16095 26345
Re03.g15960 Putative uncharacterized protein 5846 16096 26346
Re03.g15970 Uncharacterized protein 5847 16097 26347 31595 33085
Re03.g15980 Putative uncharacterized protein 5848 16098 26348
Ribosome biogenesis protein
Re03.g15990 Noc4, putative 5849 16099 26349
Mitochondrial ATPase subunit
Re03.g16000 ATP4, putative 5850 16100 26350
Re03.g16010 Putative uncharacterized protein 5851 16101 26351
Re03.g16020 hypothetical protein 5852 16102 26352
Re03.g16030 Pheromone response protein, 5853 16103 26353 putative
Re03.g16040 hypothetical protein 5854 16104 26354
Re03.g16050 BZIP transcription factor, putative 5855 16105 26355
Re03.g16060 hypothetical protein 5856 16106 26356
Re03.g16070 Uncharacterized protein 5857 16107 26357
Re03.g16080 Uncharacterized protein 5858 16108 26358
Re03.g16090 Putative uncharacterized protein 5859 16109 26359
Re03.g16100 COP9 signalosome subunit CsnD 5860 161 10 26360
Fumarate reductase Osm1 ,
Re03.g161 10 putative EC=1.3.1.6 5861 161 1 1 26361 31596 33086
Re03.g16120 Uncharacterized protein 5862 161 12 26362
Protein phosphatase PP2A
Re03.g16130 regulatory subunit B 5863 161 13 26363
Re03.g16140 Transcription factor (Sin3), putative 5864 161 14 26364
Acetyl-coA hydrolase Ach1 ,
Re03.g16150 putative 5865 161 15 26365
Re03.g16160 Uncharacterized protein 5866 161 16 26366
Re03.g16170 Putative uncharacterized protein 5867 161 17 26367 31597 33087
Re03.g16180 Uncharacterized protein 5868 161 18 26368
Re03.g16190 Putative uncharacterized protein 5869 161 19 26369
Re03.g16200 Putative uncharacterized protein 5870 16120 26370
Probable beta-glucosidase btgE
Re03.g16210 EC=3.2.1.21 Precursor 5871 16121 26371 31598 33088
Re03.g16220 hypothetical protein 5872 16122 26372
Re03.g16230 hypothetical protein 5873 16123 26373
Re03.g 16240 hypothetical protein 5874 16124 26374
Function: Hnm1 of S. cerevisiae is
the unique coline permease in
Re03.g16250 yeast 5875 16125 26375 31599 33089
Re03.g16260 Putative Choline transport protein 5876 16126 26376
Re03.g16270 hypothetical protein 5877 16127 26377
Re03.g16280 WD repeat protein 5878 16128 26378
Re03.g16290 Chitin synthase F EC=2.4.1.16 5879 16129 26379
Re03.g16300 hypothetical protein 5880 16130 26380 31600 33090
Chitin synthase activator (Chs3),
Re03.g16310 putative 5881 16131 26381
Re03.g16320 Alcohol dehydrogenase 5882 16132 26382
Re03.g16330 Dehydrogenase 5883 16133 26383
Re03.g16340 Dihydrodipicolinate synthetase 5884 16134 26384
Re03.g16350 Palmitoyltransferase EC=2.3.1.225 5885 16135 26385
Re03.g16360 DNA mismatch repair protein 5886 16136 26386
Re03.g16370 Putative uncharacterized protein 5887 16137 26387
Re03.g16380 Uncharacterized protein 5888 16138 26388 31601 33091
Re03.g16390 hypothetical protein 5889 16139 26389 31602 33092
Re03.g16400 C6 transcription factor, putative 5890 16140 26390
Re03.g16410 Uncharacterized protein Fragment 5891 16141 26391
Re03.g 16420 Putative uncharacterized protein 5892 16142 26392
Re03.g16430 Endoglucanase Cel5C 5893 16143 26393 31603 33093
Re03.g 16440 hypothetical protein 5894 16144 26394 31604 33094 Serine/threonine protein kinase,
Re03.g 16450 putative 5895 16145 26395
Re03.g 16460 OPA3 domain protein 5896 16146 26396
Re03.g16470 Myosin I MyoA/Myo5 5897 16147 26397
Re03.g16480 Putative uncharacterized protein 5898 16148 26398
Re03.g16490 Zinc/cadmium resistance protein 5899 16149 26399 31605 33095
Manganese ion homeostasis (Fr),
Re03.g16500 putative 5900 16150 26400
Pogo transposable element,
Re03.g16510 putative 5901 16151 26401
Re03.g16520 Tyrosinase 5902 16152 26402 31606 33096
Re03.g16530 hypothetical protein 5903 16153 26403
Re03.g 16540 hypothetical protein 5904 16154 26404 31607 33097
Re03.g16550 hypothetical protein 5905 16155 26405 31608 33098
Re03.g16560 hypothetical protein 5906 16156 26406 31609 33099
Re03.g16570 Putative uncharacterized protein 5907 16157 26407
S-adenosyl-L-methionine-
Re03.g16580 dependent methyltransferase 5908 16158 26408
MFS monosaccharide transporter,
Re03.g16590 putative 5909 16159 26409
Re03.g16600 Salicylate hydroxylase 5910 16160 26410 31610 33100
Re03.g16610 Pc20g 10680 protein 591 1 16161 2641 1
Re03.g16620 Glutathione S-transferase, putative 5912 16162 26412
Re03.g16630 Lipase EC=3.1.1.3 Fragment 5913 16163 26413
Re03.g 16640 Methyltransferase, putative 5914 16164 26414
Putative anhydro-n-acetylmuramic
Re03.g16650 acid kinase protein 5915 16165 26415
Re03.g16660 Putative sugar transporter protein 5916 16166 26416 3161 1 33101
Re03.g16670 Uncharacterized protein 5917 16167 26417
Re03.g16680 hypothetical protein 5918 16168 26418
Re03.g16690 hypothetical protein 5919 16169 26419 31612 33102
Re03.g16700 Oxalate decarboxylase 5920 16170 26420 31613 33103
Eukaryotic translation initiation
Re03.g16710 factor 3 subunit D 5921 16171 26421
Re03.g16720 Putative uncharacterized protein 5922 16172 26422
Re03.g16730 Uncharacterized protein 5923 16173 26423
Arsenite resistance protein Ars2,
Re03.g16740 putative 5924 16174 26424
CCAAT-binding transcription factor
Re03.g16750 subunit HAPB 5925 16175 26425
Re03.g16760 hypothetical protein 5926 16176 26426
Re03.g16770 Kinesin family protein 5927 16177 26427
Re03.g16780 Putative uncharacterized protein 5928 16178 26428
Re03.g16790 hypothetical protein 5929 16179 26429 31614 33104
Re03.g16800 DUF821 domain protein 5930 16180 26430
Re03.g16820 BCS1 -like ATPase, putative 5931 16181 26431
Re03.g16830 Predicted protein 5932 16182 26432
Re03.g16840 Predicted protein 5933 16183 26433
Re03.g16850 Type I phosphodiesterase / 5934 16184 26434 nucleotide pyrophosphatase family
protein EC=3.1.4.1
Re03.g16860 hypothetical protein 5935 16185 26435
Re03.g16870 hypothetical protein 5936 16186 26436 31615 33105
Re03.g16880 Uncharacterized protein 5937 16187 26437
HLH transcription factor (Hpa3),
Re03.g16890 putative 5938 16188 26438
Re03.g16900 Predicted protein 5939 16189 26439
Re03.g16910 Oxidoreductase, putative 5940 16190 26440
Re03.g16920 Uncharacterized protein 5941 16191 26441
Enoyl-CoA hydratase/isomerase
Re03.g16930 family protein 5942 16192 26442
Re03.g16940 Uncharacterized protein 5943 16193 26443
Transcription initiation factor TFIID
Re03.g16950 subunit 7, putative 5944 16194 26444
Bromodomain associated domain
Re03.g16960 protein 5945 16195 26445
Re03.g16970 pH-signaling protein PalC, putative 5946 16196 26446
Re03.g16980 Uncharacterized protein 5947 16197 26447
Alpha- 1 ,6-mannosyltransferase
Re03.g16990 subunit, putative 5948 16198 26448
Re03.g17000 Protein kinase, putative 5949 16199 26449
Re03.g17010 Putative uncharacterized protein 5950 16200 26450
Re03.g17020 Uncharacterized protein 5951 16201 26451
Re03.g17030 Exonuclease 5952 16202 26452
Re03.g17040 Thioredoxin, putative 5953 16203 26453
Re03.g17050 Uncharacterized protein 5954 16204 26454
Mitochondrial deoxynucleotide
Re03.g17060 carrier protein, putative 5955 16205 26455
Re03.g17070 Tubulin subunit alpha-2 5956 16206 26456
Re03.g17080 hypothetical protein 5957 16207 26457
Mechanosensitive ion channel
Re03.g17090 family 5958 16208 26458
Re03.g17100 hypothetical protein 5959 16209 26459 31616 33106
Serine threonine protein kinase,
Re03.g171 10 putative 5960 16210 26460
Re03.g17120 hypothetical protein 5961 1621 1 26461 31617 33107
Re03.g17130 Malate permease 5962 16212 26462
Re03.g17140 hypothetical protein 5963 16213 26463
Re03.g17150 Uncharacterized protein 5964 16214 26464
Re03.g17160 Uncharacterized protein 5965 16215 26465
Rho GTPase activator (Lrg1 1 ),
Re03.g17170 putative 5966 16216 26466
Re03.g17180 hypothetical protein 5967 16217 26467
Re03.g17190 Uncharacterized protein 5968 16218 26468
Complex: the P. patens RPN10 is
Re03.g17200 part of the 26S proteasome 5969 16219 26469
Re03.g17210 Trappc4 protein 5970 16220 26470
Re03.g17220 C2H2 finger domain protein 5971 16221 26471 Re03.g17230 MFS transporter 5972 16222 26472
Re03.g 17240 ABC multidrug transporter, putative 5973 16223 26473
Re03.g17250 Putative uncharacterized protein 5974 16224 26474
Re03.g17260 Beta-xylosidase EC=3.2.1.37 5975 16225 26475 31618 33108
Re03.g17270 hypothetical protein 5976 16226 26476
Re03.g17280 hypothetical protein 5977 16227 26477
Re03.g17290 Uncharacterized protein 5978 16228 26478
Re03.g17300 hypothetical protein 5979 16229 26479 31619 33109
Re03.g17310 Putative uncharacterized protein 5980 16230 26480
Re03.g17320 Ribulose-phosphate 3-epimerase 5981 16231 26481
Re03.g17330 Uncharacterized protein 5982 16232 26482
Small nuclear ribonucleoprotein
Re03.g17340 LSM2 5983 16233 26483
Re03.g17350 hypothetical protein 5984 16234 26484
DNA repair protein Pso2/Snm1 ,
Re03.g17360 putative 5985 16235 26485
UMTA methyltransferase family
Re03.g17370 protein 5986 16236 26486
Re03.g17380 Putative uncharacterized protein 5987 16237 26487
Cytochrome P450 benzoate 4-
Re03.g17390 monooxygenase, putative 5988 16238 26488
Re03.g17400 hypothetical protein 5989 16239 26489
Re03.g17410 Uncharacterized protein 5990 16240 26490
Putative glycoside hydrolase family
Re03.g 17420 39 protein 5991 16241 26491 31620 331 10
Re03.g17430 Gibberellin 20-oxidase, putative 5992 16242 26492
C6 transcription factor (Leu3),
Re03.g 17440 putative 5993 16243 26493
Small oligopeptide transporter,
Re03.g 17450 OPT family 5994 16244 26494
Re03.g 17460 Cytochrome B2, putative 5995 16245 26495
2-dehydropantoate 2-reductase
Re03.g17470 EC=1.1.1.169 5996 16246 26496
Re03.g17480 Putative uncharacterized protein 5997 16247 26497
Re03.g17490 DUF636 domain protein 5998 16248 26498
Purine nucleoside permease,
Re03.g17500 putative 5999 16249 26499 31621 331 1 1
Similar to FAD binding domain
Re03.g17510 protein 6000 16250 26500
Re03.g17520 Uncharacterized protein 6001 16251 26501
Short-chain
dehydrogenase/reductase 2,
Re03.g17530 putative 6002 16252 26502 31622 331 12
Re03.g 17540 L-xylulose reductase 6003 16253 26503
Re03.g17550 Similar to An15g07820 6004 16254 26504 31623 331 13
Re03.g17560 Uncharacterized protein 6005 16255 26505 31624 331 14
Re03.g17570 Uncharacterized protein 6006 16256 26506 31625 331 15
Re03.g17580 Uncharacterized protein 6007 16257 26507 31626 331 16
Re03.g17590 Uncharacterized protein 6008 16258 26508 Re04.g00010 hypothetical protein 6009 16259 26509
Re04.g00020 Putative uncharacterized protein 6010 16260 26510
Re04.g00030 hypothetical protein 601 1 16261 2651 1
Transposon-encoded proteins with
Re04.g00040 TYA 6012 16262 26512
Re04.g00050 Predicted protein 6013 16263 26513
Re04.g00060 Putative uncharacterized protein 6014 16264 26514
Putative uncharacterized protein
Re04.g00070 Fragment 6015 16265 26515
Putative glycosyl transferase family
Re04.g00080 8 protein 6016 16266 26516
Glycosyltransferase family 8
Re04.g00090 protein 6017 16267 26517
Polygalacturonase 2 EC=3.2.1.15
Re04.g00100 Precursor 6018 16268 26518 31627 331 17
Re04.g001 10 Uncharacterized protein 6019 16269 26519
Re04.g00120 Uncharacterized protein 6020 16270 26520
Re04.g00130 Uncharacterized protein 6021 16271 26521
Re04.g00140 Uncharacterized protein 6022 16272 26522
Re04.g00150 Putative uncharacterized protein 6023 16273 26523 31628 331 18
Re04.g00160 hypothetical protein 6024 16274 26524
Re04.g00170 Uncharacterized protein 6025 16275 26525
Re04.g00180 hypothetical protein 6026 16276 26526
Re04.g00190 Putative uncharacterized protein 6027 16277 26527
Re04.g00200 PQ loop repeat protein 6028 16278 26528
Re04.g00210 Conserved serine-rich protein 6029 16279 26529
Re04.g00220 Uncharacterized protein 6030 16280 26530
Re04.g00230 Uncharacterized protein 6031 16281 26531
Re04.g00240 Steroid monooxygenase 6032 16282 26532
Re04.g00250 Beta-lactamase family protein 6033 16283 26533
Re04.g00260 C6 transcription factor AlcR 6034 16284 26534
Re04.g00270 Putative uncharacterized protein 6035 16285 26535
Re04.g00280 Malate/L-lactate dehydrogenase 6036 16286 26536
Stress response protein (Ish 1 ),
Re04.g00290 putative 6037 16287 26537 31629 331 19
DNA damage response protein
Re04.g00300 (Dap1 ), putative 6038 16288 26538
Re04.g00310 Similar to An16g04440 6039 16289 26539
Re04.g00320 hypothetical protein 6040 16290 26540
Serine/threonine protein kinase
Re04.g00330 (Prp4), putative 6041 16291 26541
Re04.g00340 hypothetical protein 6042 16292 26542
Protein serine/threonine kinase
Re04.g00350 (Rani ), putative 6043 16293 26543
Re04.g00360 Uncharacterized protein 6044 16294 26544 31630 33120
3-oxoacyl-(Acyl-carrier-protein)
Re04.g00370 reductase, putative 6045 16295 26545
Re04.g00380 Uncharacterized protein 6046 16296 26546
Re04.g00390 Predicted protein 6047 16297 26547 Haemolysin-lll channel protein
Re04.g00400 Izh2, putative 6048 16298 26548
Re04.g00410 Putative uncharacterized protein 6049 16299 26549
Re04.g00420 Uncharacterized protein 6050 16300 26550
Dolichol-phosphate
Re04.g00430 mannosyltransferase 6051 16301 26551
Re04.g00440 Uncharacterized protein 6052 16302 26552
Re04.g00450 Uncharacterized protein 6053 16303 26553
Transcription factor TFIIIC complex
Re04.g00460 subunit Tfc6 6054 16304 26554
Re04.g00470 hypothetical protein 6055 16305 26555 31631 33121
Re04.g00480 Uncharacterized protein 6056 16306 26556
Re04.g00490 hypothetical protein 6057 16307 26557
Re04.g00500 Serine/threonine protein kinase 6058 16308 26558
RNA polymerase II mediator
Re04.g00510 complex protein Nut2, putative 6059 16309 26559
Re04.g00520 Integral membrane protein 6060 16310 26560
Re04.g00530 Putative uncharacterized protein 6061 16311 26561 31632 33122
Probable zinc metalloprotease
Re04.g00540 PMAA_024220 EC=3.4.-.- 6062 16312 26562
Ubiquitin ligase complex F-box
Re04.g00550 protein GRR1 , putative 6063 16313 26563
AMP-binding domain protein,
Re04.g00560 putative 6064 16314 26564 31633 33123
Re04.g00570 60S ribosomal protein L16 6065 16315 26565
Re04.g00580 Phosphoesterases 6066 16316 26566
Re04.g00590 DnaJ domain protein 6067 16317 26567
Re04.g00600 hypothetical protein 6068 16318 26568
AP-1 adaptor complex subunit
Re04.g00610 gamma, putative 6069 16319 26569
Re04.g00620 O-acyltransferase 6070 16320 26570
Re04.g00630 Putative uncharacterized protein 6071 16321 26571 31634 33124
Re04.g00640 Uncharacterized protein 6072 16322 26572
Re04.g00650 Putative uncharacterized protein 6073 16323 26573 31635 33125
Re04.g00660 BAG domain protein 6074 16324 26574
Re04.g00670 Putative uncharacterized protein 6075 16325 26575
Re04.g00680 Glutaredoxin Grx1 , putative 6076 16326 26576
Re04.g00690 Putative uncharacterized protein 6077 16327 26577
Re04.g00700 Uncharacterized protein 6078 16328 26578
Re04.g00710 Putative uncharacterized protein 6079 16329 26579
Re04.g00720 Elongation factor 1 -alpha 6080 16330 26580
DNA-directed RNA polymerase
Re04.g00730 subunit 6081 16331 26581
Re04.g00740 Ankyrin repeat protein 6082 16332 26582
Re04.g00750 Alpha-L-rhamnosidase B, putative 6083 16333 26583 31636 33126
Extracellular exo-
Re04.g00760 polygalacturonase, putative 6084 16334 26584 31637 33127
Re04.g00770 Putative uncharacterized protein 6085 16335 26585
Re04.g00780 Uncharacterized protein 6086 16336 26586 31638 33128 Re04.g00790 Uncharacterized protein 6087 16337 26587
Re04.g00800 hypothetical protein 6088 16338 26588
Re04.g00810 hypothetical protein 6089 16339 26589
Glucose-methanol-choline (Gmc)
Re04.g00820 oxidoreductase, putative 6090 16340 26590
Re04.g00830 Uncharacterized protein 6091 16341 26591
RNA polymerase II mediator
Re04.g00840 complex subunit Soh1 , putative 6092 16342 26592
Re04.g00850 Putative uncharacterized protein 6093 16343 26593
Re04.g00860 Putative uncharacterized protein 6094 16344 26594 31639 33129
Re04.g00870 PHD transcription factor, putative 6095 16345 26595
Re04.g00880 hypothetical protein 6096 16346 26596
Re04.g00890 Sigma-70 region 2 family protein 6097 16347 26597
Re04.g00900 Sugar transporter 6098 16348 26598 31640 33130
Re04.g00910 Putative uncharacterized protein 6099 16349 26599
Re04.g00920 hypothetical protein 6100 16350 26600
C6 transcription factor (Mut3),
Re04.g00930 putative 6101 16351 26601
Re04.g00940 Oxidoreductase, putative 6102 16352 26602
pH-response transcription factor
Re04.g00950 pacC/RIM101 6103 16353 26603
Forkhead transcription factor
Re04.g00960 Fkh1/2, putative 6104 16354 26604
Fungal specific transcription factor,
Re04.g00970 putative 6105 16355 26605
NAD binding Rossmann fold
Re04.g00980 oxidoreductase, putative 6106 16356 26606
Dihydrodipicolinate synthetase
Re04.g00990 family protein 6107 16357 26607
Re04.g01000 Oxidoreductase, zinc-binding 6108 16358 26608
Re04.g01010 Uncharacterized protein 6109 16359 26609
Re04.g01020 Uncharacterized protein 61 10 16360 26610
Re04.g01030 Microtubule associated protein 61 1 1 16361 2661 1
Re04.g01040 Putative uncharacterized protein 61 12 16362 26612
Re04.g01050 RTA1 domain protein, putative 61 13 16363 26613
PHD finger domain protein,
Re04.g01060 putative 61 14 16364 26614
Re04.g01070 QDE-2-interacting protein 61 15 16365 26615
Transcription regulator PAB1642,
Re04.g01080 putative 61 16 16366 26616
Calcium-translocating P-type
Re04.g01090 ATPase(PMCA-type),putative 61 17 16367 26617
Actin-related protein 2/3 complex
Re04.g01 100 subunit 5 61 18 16368 26618
Re04.g01 1 10 Putative uncharacterized protein 61 19 16369 26619 31641 33131
Re04.g01 120 Dynactin Arp1 p62 subunit R02 6120 16370 26620
Re04.g01 130 40S ribosomal protein S7e 6121 16371 26621
RAB GTPase Vps21/Ypt51 ,
Re04.g01 140 putative 6122 16372 26622 Re04.g01150 Acetate kinase, putative 6123 16373 26623
D-xylulose 5-phosphate/D-fructose
6-phosphate phosphoketolase,
Re04.g01160 putative 6124 16374 26624
Re04.g01170 Uncharacterized protein 6125 16375 26625 31642 33132
Short chain dehydrogenase
Re04.g01180 reductase family 6126 16376 26626
Re04.g01190 RTA1 domain protein, putative 6127 16377 26627
Re04.g01200 Uncharacterized protein 6128 16378 26628
Re04.g01210 Putative uncharacterized protein 6129 16379 26629
Clustered mitochondria protein
Re04.g01220 homolog 6130 16380 26630
Re04.g01230 Putative uncharacterized protein 6131 16381 26631
Re04.g01240 Ferric-chelate reductase, putative 6132 16382 26632 31643 33133
Re04.g01250 Putative uncharacterized protein 6133 16383 26633
Zinc knuckle transcription
factor/splicing factor MSL5/ZFM1 ,
Re04.g01260 putative 6134 16384 26634
Re04.g01270 Uncharacterized protein 6135 16385 26635
ATP dependent RNA helicase
Re04.g01280 (Dbp8), putative 6136 16386 26636
Re04.g01290 Uncharacterized protein 6137 16387 26637
Re04.g01300 hypothetical protein 6138 16388 26638
Re04.g01310 Glutaminase, putative 6139 16389 26639 31644 33134
Telomere and ribosome associated
Re04.g01320 protein Stm1 6140 16390 26640
BZIP transcription factor (MeaB),
Re04.g01330 putative 6141 16391 26641
Re04.g01340 Amine oxidase 6142 16392 26642
Peroxisomal membrane protein
Re04.g01350 receptor Pex19, putative 6143 16393 26643
Re04.g01360 Uncharacterized protein 6144 16394 26644
Re04.g01370 Uncharacterized protein 6145 16395 26645
Re04.g01380 Cell wall protein, putative 6146 16396 26646 31645 33135
Re04.g01390 Uncharacterized protein 6147 16397 26647
Re04.g01400 VanZ domain protein, putative 6148 16398 26648 31646 33136
Re04.g01410 Bromodomain protein 6149 16399 26649
Eukaryotic translation initiation
Re04.g01420 factor 2c 6150 16400 26650
Re04.g01430 CFIA complex component Rna14 6151 16401 26651
Re04.g01440 Histone chaperone asfl 6152 16402 26652
SNARE-dependent exocytosis
Re04.g01450 protein (Sro7), putative 6153 16403 26653
Re04.g01460 Uncharacterized protein 6154 16404 26654
Re04.g01470 THUMP domain protein 6155 16405 26655
Re04.g01480 Pyruvate decarboxylase 6156 16406 26656
MAP kinase kinase kinase (Bck1),
Re04.g01490 putative 6157 16407 26657
Re04.g01500 Golgi complex component Cog3, 6158 16408 26658 putative
Mitochondrial protein Fmp25,
Re04.g01510 putative 6159 16409 26659
Re04.g01520 rRNA processing protein Nop9 6160 16410 26660
Re04.g01530 Similar to An13g01270 6161 16411 26661
Re04.g01540 Uncharacterized protein 6162 16412 26662
Re04.g01550 Uncharacterized protein 6163 16413 26663
Re04.g01560 DNA ligase I, putative 6164 16414 26664
Re04.g01570 Putative uncharacterized protein 6165 16415 26665
Re04.g01580 Putative uncharacterized protein 6166 16416 26666
Putative acetolactate synthase
Re04.g01590 protein 6167 16417 26667
Re04.g01600 CP2 transcription factor 6168 16418 26668
Re04.g01610 hypothetical protein 6169 16419 26669
Re04.g01620 hypothetical protein 6170 16420 26670 31647 33137
Vacuolar assembly protein,
Re04.g01630 putative 6171 16421 26671
Re04.g01640 YagE family protein 6172 16422 26672
Re04.g01650 Ribonuclease T2 family, putative 6173 16423 26673
Re04.g01660 C2H2 transcription factor 6174 16424 26674
Re04.g01670 Ubiquitin 6175 16425 26675
Re04.g01680 Endochitinase 6176 16426 26676
Re04.g01690 Uncharacterized protein 6177 16427 26677
Re04.g01700 Proteasome subunit alpha type 6178 16428 26678 31648 33138
Re04.g01710 hypothetical protein 6179 16429 26679
Remark: Homology is mainly based
Re04.g01720 on repetitive sequences 6180 16430 26680
Re04.g01730 Putative uncharacterized protein 6181 16431 26681
BZIP transcription factor (AtfA),
Re04.g01740 putative 6182 16432 26682
Re04.g01750 Transthyretin domain protein 6183 16433 26683
Re04.g01760 ATPase get3 EC=3.6.-.- 6184 16434 26684
Eukaryotic translation initiation
Re04.g01770 factor 3 subunit E 6185 16435 26685
Mitochondrial large ribosomal
Re04.g01780 subunit L49, putative 6186 16436 26686 31649 33139
ARID/BRIGHT domain protein
Re04.g01790 (SWI1), putative 6187 16437 26687
Proteasome regulatory particle
Re04.g01800 subunit Rpt3, putative 6188 16438 26688
Aspartic endopeptidase Pep2
Re04.g01810 EC=3.4.23.25 6189 16439 26689 31650 33140
RNA Polymerase II CTD
Re04.g01820 phosphatase Fcp1 , putative 6190 16440 26690
Re04.g01830 Putative uncharacterized protein 6191 16441 26691
Re04.g01840 Putative uncharacterized protein 6192 16442 26692
Re04.g01850 Putative uncharacterized protein 6193 16443 26693
Re04.g01860 Predicted protein 6194 16444 26694
Re04.g01870 Putative uncharacterized protein 6195 16445 26695 Re04.g01880 Arginase, putative 6196 16446 26696
Glutamyl-tRNA(Gln)
Re04.g01890 amidotransferase, B subunit 6197 16447 26697
Re04.g01900 Uncharacterized protein 6198 16448 26698
Re04.g01910 Uncharacterized protein 6199 16449 26699
Re04.g01920 Uncharacterized protein 6200 16450 26700
Mitochondrial methylglutaconyl-
Re04.g01930 CoA hydratase 6201 16451 26701
Re04.g01940 Catalytic protein Fragment 6202 16452 26702
Re04.g01950 hypothetical protein 6203 16453 26703
Re04.g01960 Uncharacterized protein 6204 16454 26704
Aspergillus niger contig
An14c0130, genomic contig
Re04.g01970 Precursor 6205 16455 26705 31651 33141
Re04.g01980 Lipase/esterase, putative 6206 16456 26706 31652 33142
Re04.g01990 Putative uncharacterized protein 6207 16457 26707
Re04.g02000 Putative uncharacterized protein 6208 16458 26708
Taz1 -interacting factor 1 (TAF1),
Re04.g02010 putative 6209 16459 26709
Re04.g02020 Uncharacterized protein 6210 16460 26710
Re04.g02030 hypothetical protein 6211 16461 26711 31653 33143
Re04.g02040 Uncharacterized protein 6212 16462 26712
Re04.g02050 Uncharacterized protein 6213 16463 26713
Re04.g02060 Putative uncharacterized protein 6214 16464 26714
Homoserine dehydrogenase
Re04.g02070 EC=1.1.1.3 6215 16465 26715 31654 33144
Re04.g02080 Putative uncharacterized protein 6216 16466 26716
Re04.g02090 Putative uncharacterized protein 6217 16467 26717
Re04.g02100 Uncharacterized protein Fragment 6218 16468 26718
Re04.g02120 DUF221 domain protein, putative 6219 16469 26719
Fructose-bisphosphate aldolase,
Re04.g02130 class II 6220 16470 26720
Ubiquitin carboxyl-terminal
Re04.g02140 hydrolase EC=3.4.19.12 6221 16471 26721
Saccharopine dehydrogenase
Re04.g02150 Lys1 , putative 6222 16472 26722
Re04.g02160 Uncharacterized protein 6223 16473 26723
Re04.g02170 Uncharacterized protein 6224 16474 26724
FAD binding domain-containing
Re04.g02180 protein 6225 16475 26725
Oxysterol binding protein (Osh5),
Re04.g02190 putative 6226 16476 26726
Re04.g02200 Predicted protein 6227 16477 26727
Re04.g02210 Putative uncharacterized protein 6228 16478 26728
Re04.g02220 Predicted protein Fragment 6229 16479 26729
Re04.g02230 Uncharacterized protein 6230 16480 26730
Re04.g02240 Aryl-alcohol dehydrogenase 6231 16481 26731 31655 33145
Re04.g02250 Pc12g03750 protein 6232 16482 26732
Re04.g02260 Uncharacterized protein 6233 16483 26733 Re04.g02270 Uncharacterized protein 6234 16484 26734
Re04.g02280 Uncharacterized protein 6235 16485 26735
Re04.g02290 Uncharacterized protein 6236 16486 26736
Re04.g02300 Uncharacterized protein 6237 16487 26737
Re04.g02310 Putative uncharacterized protein 6238 16488 26738
Re04.g02320 Aldo/keto reductase, putative 6239 16489 26739
Serine/threonine-protein kinase
Re04.g02330 RI01 EC=2.7.1 1.1 6240 16490 26740
Re04.g02340 Uncharacterized protein 6241 16491 26741
Re04.g02350 ABC multidrug transporter, putative 6242 16492 26742
Putative isoflavone reductase
Re04.g02360 family protein 6243 16493 26743 31656 33146
Re04.g02370 Uncharacterized protein 6244 16494 26744 31657 33147
Bicyclomycin resistance protein,
Re04.g02380 putative 6245 16495 26745
Beta-N-acetylglucosaminidase,
Re04.g02390 putative 6246 16496 26746
Re04.g02400 Uncharacterized protein 6247 16497 26747
Re04.g02410 Galactose-proton symport 6248 16498 26748
Re04.g02420 hypothetical protein 6249 16499 26749
Re04.g02430 Allantoate permease, putative 6250 16500 26750
Re04.g02440 Uncharacterized protein 6251 16501 26751
Re04.g02450 Putative uncharacterized protein 6252 16502 26752
Re04.g02460 Uncharacterized protein Fragment 6253 16503 26753
Re04.g02470 RNA exonuclease Rex2, putative 6254 16504 26754
Phosphoglucomutase PgmA
Re04.g02480 EC=5.4.2.2 6255 16505 26755
NAD binding Rossmann fold
Re04.g02490 oxidoreductase, putative 6256 16506 26756
Re04.g02500 FAD binding domain protein 6257 16507 26757
Re04.g02510 Putative uncharacterized protein 6258 16508 26758
Re04.g02520 Uncharacterized protein 6259 16509 26759 31658 33148
Re04.g02530 Putative uncharacterized protein 6260 16510 26760
Re04.g02540 hypothetical protein 6261 1651 1 26761 31659 33149
Hydroxymethylglutaryl-CoA
Re04.g02550 synthase, putative 6262 16512 26762
Glutamate carboxypeptidase Tre2,
Re04.g02560 putative EC=3.4.17.21 6263 16513 26763
Re04.g02570 Transcription initiation protein 6264 16514 26764
Re04.g02580 Putative uncharacterized protein 6265 16515 26765
Re04.g02590 Putative uncharacterized protein 6266 16516 26766
Re04.g02600 Uncharacterized protein 6267 16517 26767
Re04.g02610 Putative uncharacterized protein 6268 16518 26768
Re04.g02620 Uncharacterized protein 6269 16519 26769
Re04.g02630 Putative uncharacterized protein 6270 16520 26770
Re04.g02640 hypothetical protein 6271 16521 26771
Re04.g02650 Putative uncharacterized protein 6272 16522 26772
Clathrin-coated vesicle protein,
Re04.g02660 putative 6273 16523 26773 Re04.g02670 Nuclear transport factor 2 6274 16524 26774
Re04.g02680 Putative uncharacterized protein 6275 16525 26775
Re04.g02690 Putative uncharacterized protein 6276 16526 26776
Re04.g02700 Uncharacterized protein Fragment 6277 16527 26777 31660 33150
Re04.g02710 Putative chitinase 6278 16528 26778 31661 33151
Ser/Thr protein phosphatase family
Re04.g02720 protein 6279 16529 26779 31662 33152
TAM domain methyltransferase,
Re04.g02730 putative 6280 16530 26780
Re04.g02740 C6 transcription factor, putative 6281 16531 26781
Re04.g02750 Monooxygenase 6282 16532 26782
Re04.g02760 Uncharacterized protein 6283 16533 26783
Re04.g02770 Uncharacterized protein 6284 16534 26784
Alcohol dehydrogenase, zinc-
Re04.g02780 containing, putative 6285 16535 26785
Re04.g02790 Uncharacterized protein 6286 16536 26786
Re04.g02800 Uncharacterized protein 6287 16537 26787
Re04.g02810 LIM domain protein 6288 16538 26788
Myo-inositol-phosphate synthase,
Re04.g02820 putative EC=5.5.1.4 6289 16539 26789
Re04.g02830 Formaldehyde dehydrogenase 6290 16540 26790
Re04.g02840 hypothetical protein 6291 16541 26791
Mitochondrial intermembrane
space translocase subunit Tim9,
Re04.g02850 putative 6292 16542 26792
Rho GTPase activator (Sac7),
Re04.g02860 putative 6293 16543 26793
GPI-anchor biosynthesis protein
Re04.g02870 (Pig-F), putative 6294 16544 26794 31663 33153
Re04.g02880 Uncharacterized protein 6295 16545 26795
Re04.g02890 hypothetical protein 6296 16546 26796
Re04.g02900 DNA helicase, putative 6297 16547 26797
Re04.g02910 Uncharacterized protein 6298 16548 26798
Re04.g02920 Predicted protein 6299 16549 26799
Re04.g02930 Uncharacterized protein 6300 16550 26800
Re04.g02940 DNA repair protein, putative 6301 16551 26801
Ubiquitin conjugating enzyme
Re04.g02950 (UbcJ), putative 6302 16552 26802
Re04.g02960 hypothetical protein 6303 16553 26803 31664 33154
Cellobiohydrolase 1 catalytic
Re04.g02970 domain EC=3.2.1.91 EC=3.2.1.91 6304 16554 26804 31665 33155
Re04.g02980 hypothetical protein 6305 16555 26805
Re04.g02990 MFS transporter, putative 6306 16556 26806
Re04.g03000 Similar to An13g02410 6307 16557 26807
Aspergillus niger contig
Re04.g03010 An14c0100, genomic contig 6308 16558 26808
Re04.g03020 hypothetical protein 6309 16559 26809
Re04.g03030 Reverse transcriptase, putative 6310 16560 26810
Re04.g03040 hypothetical protein 631 1 16561 2681 1 Re04.g03050 Uncharacterized protein 6312 16562 26812
Re04.g03060 Uncharacterized protein 6313 16563 26813
Re04.g03070 Uncharacterized protein 6314 16564 26814
Re04.g03080 Uncharacterized protein 6315 16565 26815
Re04.g03090 Reverse transcriptase, putative 6316 16566 26816
Re04.g03100 Multicopper oxidase, putative 6317 16567 26817 31666 33156
Re04.g031 10 Uncharacterized protein 6318 16568 26818
Re04.g03120 hypothetical protein 6319 16569 26819
NADP(+)-dependent
Re04.g03130 dehydrogenase, putative 6320 16570 26820 31667 33157
Extracellular GDSL-like
Re04.g03140 I ipase/acyl hydrolase 6321 16571 26821 31668 33158
1 ,3-beta-glucanosyltransferase
Re04.g03150 Gel1 6322 16572 26822 31669 33159
Re04.g03160 Putative uncharacterized protein 6323 16573 26823
Re04.g03170 Putative uncharacterized protein 6324 16574 26824
AflR-like C6 zinc cluster
Re04.g03180 transcription factor, putative 6325 16575 26825
Re04.g03190 Putative uncharacterized protein 6326 16576 26826
Actin polymerization protein Bzz1 ,
Re04.g03200 putative 6327 16577 26827
ATP dependent RNA helicase
Re04.g03210 (Dbp5), putative 6328 16578 26828
Re04.g03220 Uracil phosphoribosyltransferase 6329 16579 26829
Re04.g03230 GTP cyclohydrolase II, putative 6330 16580 26830
Re04.g03240 Uncharacterized protein 6331 16581 26831
Re04.g03250 Uncharacterized protein 6332 16582 26832
Re04.g03260 hypothetical protein 6333 16583 26833
Re04.g03270 TPR repeat protein 6334 16584 26834
Re04.g03280 Uncharacterized protein 6335 16585 26835
Re04.g03290 hypothetical protein 6336 16586 26836
Re04.g03300 Hexose transporter 6337 16587 26837 31670 33160
GAF domain nucleotide-binding
Re04.g03310 protein 6338 16588 26838
Re04.g03320 NAD+ kinase Utr1 , putative 6339 16589 26839
Re04.g03330 Pc20g05810 protein 6340 16590 26840
Re04.g03340 FAD-binding protein DIMINUTO 6341 16591 26841
Re04.g03350 Pc20g05840 protein 6342 16592 26842
Re04.g03360 HLH transcription factor, putative 6343 16593 26843
Re04.g03370 Uncharacterized protein 6344 16594 26844
Short chain
dehydrogenase/oxidoreductase,
Re04.g03380 putative 6345 16595 26845
Re04.g03390 Putative uncharacterized protein 6346 16596 26846
AP-1 adaptor complex subunit
Re04.g03400 sigma, putative 6347 16597 26847
Re04.g03410 Putative uncharacterized protein 6348 16598 26848
Re04.g03420 hypothetical protein 6349 16599 26849
Re04.g03430 Uncharacterized protein 6350 16600 26850 31671 33161 Re04.g03440 Uncharacterized protein 6351 16601 26851
Glycoside hydrolase family 10
Re04.g03450 xylanase 6352 16602 26852 31672 33162
Re04.g03460 Putative uncharacterized protein 6353 16603 26853
Re04.g03470 Uncharacterized protein 6354 16604 26854
Re04.g03480 Uncharacterized protein 6355 16605 26855 31673 33163
Re04.g03490 Uncharacterized protein 6356 16606 26856
Re04.g03500 Allergen, putative 6357 16607 26857
Re04.g03510 Putative uncharacterized protein 6358 16608 26858
Re04.g03520 COPII-coated vesicle protein 6359 16609 26859
Re04.g03530 Protein kinase, putative 6360 16610 26860
Integral peroxisomal membrane
Re04.g03540 peroxin, putative 6361 1661 1 26861
Re04.g03550 Uncharacterized protein 6362 16612 26862
60S ribosomal subunit biogenesis
Re04.g03560 protein Nop16, putative 6363 16613 26863
Re04.g03570 ZIP Zinc transporter 6364 16614 26864 31674 33164
Re04.g03580 Putative uncharacterized protein 6365 16615 26865 31675 33165
Re04.g03590 Uncharacterized protein 6366 16616 26866
Alpha-1 ,6 mannosyltransferase
Re04.g03600 subunit (Mnn9), putative 6367 16617 26867 31676 33166
Alpha-1 ,6 mannosyltransferase
Re04.g03610 subunit (Mnn9), putative 6368 16618 26868 31677 33167
Re04.g03620 hypothetical protein 6369 16619 26869
Re04.g03630 hypothetical protein 6370 16620 26870
Re04.g03640 Putative uncharacterized protein 6371 16621 26871
Re04.g03650 O-methyltransferase, putative 6372 16622 26872
Re04.g03660 Cytochrome P450 6373 16623 26873
Re04.g03670 Putative endochitinase 6374 16624 26874 31678 33168
Re04.g03680 Cyclohexanone monooxygenase 6375 16625 26875
Re04.g03690 Trichothecene efflux pump 6376 16626 26876
Putative gluconate 5-
Re04.g03700 dehydrogenase protein 6377 16627 26877
Mannosyl-oligosaccharide 1 ,2-
Re04.g03710 alpha-mannosidase 6378 16628 26878
Re04.g03720 Putative uncharacterized protein 6379 16629 26879
Re04.g03730 Putative uncharacterized protein 6380 16630 26880
Re04.g03740 Uncharacterized protein 6381 16631 26881 31679 33169
Similar to Uncharacterized MFS- type transporter C1271.10c acc.
Re04.g03750 no. 094343 6382 16632 26882
Re04.g03760 Uncharacterized protein 6383 16633 26883 31680 33170
Re04.g03770 Uncharacterized protein 6384 16634 26884
Zinc-binding alcohol
Re04.g03780 dehydrogenase 6385 16635 26885
Re04.g03790 Uncharacterized protein 6386 16636 26886 31681 33171
Dihydrodipicolinate synthetase
Re04.g03800 family protein 6387 16637 26887
Re04.g03810 Protein kinase, putative 6388 16638 26888 Gamma-cysteine synthetase
Re04.g03820 regulatory subunit, putative 6389 16639 26889
Re04.g03830 Aldo-keto reductase, putative 6390 16640 26890
Re04.g03840 Pc20g 10680 protein 6391 16641 26891
Re04.g03850 Uncharacterized protein 6392 16642 26892
Re04.g03860 Uncharacterized protein 6393 16643 26893
Alcohol dehydrogenase
Re04.g03870 superfamily zinc-containing 6394 16644 26894
Re04.g03880 Putative uncharacterized protein 6395 16645 26895
Benzoate 4-monooxygenase
Re04.g03890 cytochrome P450, putative 6396 16646 26896 31682 33172
Efflux pump antibiotic resistance
Re04.g03900 protein, putative 6397 16647 26897
Re04.g03910 Cytochrome P450, putative 6398 16648 26898
Integral membrane protein Pth 1 1 -
Re04.g03920 like, putative 6399 16649 26899
Re04.g03930 Putative uncharacterized protein 6400 16650 26900
Re04.g03940 hypothetical protein 6401 16651 26901
Re04.g03950 Putative uncharacterized protein 6402 16652 26902
Re04.g03960 Predicted protein 6403 16653 26903
Endosomal sorting complex protein
Re04.g03970 TSG101 , putative 6404 16654 26904
Re04.g03980 BAR adaptor protein RVS167 6405 16655 26905
Cysteine desulfurase,
Re04.g03990 mitochondrial 6406 16656 26906 31683 33173
Indoleamine 2,3-dioxygenase
Re04.g04000 subfamily 6407 16657 26907
Re04.g04010 hypothetical protein 6408 16658 26908
Re04.g04020 Putative uncharacterized protein 6409 16659 26909
Putative uncharacterized protein
Re04.g04030 Fragment 6410 16660 26910
Re04.g04040 L-lysine 2,3-aminomutase, putative 641 1 16661 2691 1
Re04.g04050 hypothetical protein 6412 16662 26912
Re04.g04060 Putative uncharacterized protein 6413 16663 26913
Re04.g04070 Uncharacterized protein 6414 16664 26914
Re04.g04080 Putative uncharacterized protein 6415 16665 26915
Re04.g04090 Pc12g08960 protein 6416 16666 26916
Re04.g04100 C-4 methylsterol oxidase 6417 16667 26917
Function: Tto1 can transpose
autonomously through reverse
transcription EC=2.7.7.49
EC=2.7.7.49 EC=2.7.7.49
Re04.g041 10 EC=2.7.7.49 6418 16668 26918
Re04.g04120 hypothetical protein 6419 16669 26919
Re04.g04130 Uncharacterized protein 6420 16670 26920
Re04.g04140 hypothetical protein 6421 16671 26921 31684 33174
Re04.g04150 C6 transcription factor, putative 6422 16672 26922
Re04.g04160 hypothetical protein 6423 16673 26923
Re04.g04170 Uncharacterized protein 6424 16674 26924 Re04.g04180 Putative uncharacterized protein 6425 16675 26925
Re04.g04190 Putative uncharacterized protein 6426 16676 26926
Re04.g04200 hypothetical protein 6427 16677 26927
Re04.g04210 Uncharacterized protein Fragment 6428 16678 26928 31685 33175
Re04.g04220 Isoflavone reductase family protein 6429 16679 26929
Homeobox transcription factor,
Re04.g04230 putative 6430 16680 26930
Re04.g04240 Reverse transcriptase, putative 6431 16681 26931
Homeobox transcription factor,
Re04.g04250 putative 6432 16682 26932
Putative uncharacterized protein
An02g08270 EC=1.4.3.4
Re04.g04260 EC=1.5.3.1 1 Precursor 6433 16683 26933
Re04.g04270 Putative uncharacterized protein 6434 16684 26934
Re04.g04280 Putative uncharacterized protein 6435 16685 26935
Re04.g04290 Uncharacterized protein 6436 16686 26936
Re04.g04300 Putative uncharacterized protein 6437 16687 26937
Re04.g04310 Fatty acid oxygenase, putative 6438 16688 26938
Re04.g04320 Dynactin Arp1 p25 subunit 6439 16689 26939
Re04.g04330 Trehalose synthase 6440 16690 26940
Re04.g04340 ADP-ribosylation factor 6 6441 16691 26941
Re04.g04350 Putative uncharacterized protein 6442 16692 26942
Methionine synthase, vitamin-B12
Re04.g04360 independent, putative 6443 16693 26943
Re04.g04370 Uncharacterized protein 6444 16694 26944
DNA replication licensing factor
Re04.g04380 Mcm2, putative 6445 16695 26945
Metaphase-anaphase transition
Re04.g04390 protein (Mlo2), putative 6446 16696 26946
Re04.g04400 Uncharacterized protein 6447 16697 26947
Re04.g04410 hypothetical protein 6448 16698 26948
Re04.g04420 Mis12-Mtw1 family protein 6449 16699 26949
Phosphatidylserine decarboxylase
Re04.g04430 Psd2, putative 6450 16700 26950
Re04.g04440 MFS glucose transporter, putative 6451 16701 26951 31686 33176
Serine/threonine-protein kinase
Re04.g04450 ssn3 EC=2.7.1 1.22 EC=2.7.1 1.23 6452 16702 26952
Re04.g04460 Putative uncharacterized protein 6453 16703 26953
APSES transcription factor,
Re04.g04470 putative 6454 16704 26954
NADH-ubiquinone oxidoreductase
Re04.g04480 B18 subunit, putative 6455 16705 26955
Glutamate-cysteine ligase Gcs1 ,
Re04.g04490 putative 6456 16706 26956
Re04.g04500 Putative uncharacterized protein 6457 16707 26957
Re04.g04510 hypothetical protein 6458 16708 26958
Putative uncharacterized protein
Re04.g04520 An02g09610 6459 16709 26959 31687 33177
Re04.g04530 Ankyrin repeat domain protein 6460 16710 26960 Putative umta methyltransferase
Re04.g04540 family protein 6461 1671 1 26961
Re04.g04550 Cytochrome P450 52A1 6462 16712 26962 31688 33178
Re04.g04560 Uncharacterized protein 6463 16713 26963
Re04.g04570 Uncharacterized protein 6464 16714 26964
ATP-binding cassette, subfamily B
Re04.g04580 (MDR/TAP), member 1 6465 16715 26965
Re04.g04590 Predicted protein 6466 16716 26966 31689 33179
Similar to solid-state culture
Re04.g04600 specific protein 6467 16717 26967
Similar to solid-state culture
Re04.g04610 specific protein 6468 16718 26968
Re04.g04620 Alcohol dehydrogenase, putative 6469 16719 26969
Re04.g04630 Cytochrome P450 6470 16720 26970 31690 33180
Re04.g04640 hypothetical protein 6471 16721 26971 31691 33181
Hybrid NRPS/PKS enzyme,
Re04.g04650 putative 6472 16722 26972
Metallophosphoesterase domain-
Re04.g04660 containing protein 6473 16723 26973
von Willebrand domain-containing
Re04.g04670 protein 6474 16724 26974
GNAT family acetyltransferase,
Re04.g04680 putative 6475 16725 26975
Re04.g04690 LRP16 family protein 6476 16726 26976
Mitochondrial inner membrane
Re04.g04700 protease subunit Imp2, putative 6477 16727 26977
Re04.g04710 PH domain protein 6478 16728 26978
Re04.g04720 Uncharacterized protein 6479 16729 26979
Re04.g04730 Cation transporting ATPase 6480 16730 26980
Glycerol-3-phosphate 0- acyltransferase, putative
Re04.g04740 EC=2.3.1.15 6481 16731 26981
Thermophilic desulfurizing enzyme
Re04.g04750 family protein 6482 16732 26982
Vacuolar segregation protein
Re04.g04760 (Pep7), putative 6483 16733 26983 31692 33182
Potassium ion channel Yvc1 ,
Re04.g04770 putative 6484 16734 26984 31693 33183
Putative eukaryotic translation
Re04.g04780 initiation factor 2 alpha subunit 6485 16735 26985
Re04.g04790 Sulfate transporter, putative 6486 16736 26986
Re04.g04800 Uncharacterized protein 6487 16737 26987
Remark: N-terminally truncated
ORF due to the end of contig
Re04.g04810 Fragment 6488 16738 26988
Re04.g04820 Putative uncharacterized protein 6489 16739 26989
Efflux pump antibiotic resistance
Re04.g04830 protein, putative 6490 16740 26990
Re04.g04840 Uncharacterized protein 6491 16741 26991
Re04.g04850 Palmitoyl-protein thioesterase 6492 16742 26992 31694 33184 Re04.g04860 Uncharacterized protein 6493 16743 26993
Re04.g04870 Putative uncharacterized protein 6494 16744 26994
Re04.g04880 C2H2 finger domain protein 6495 16745 26995
RNA polymerase II Elongator
complex associated protein Kti12,
Re04.g04890 putative 6496 16746 26996
Re04.g04900 Uncharacterized protein 6497 16747 26997
Re04.g04910 hypothetical protein 6498 16748 26998
Re04.g04920 hypothetical protein 6499 16749 26999
Re04.g04930 Uncharacterized protein Fragment 6500 16750 27000
Re04.g04940 Uncharacterized protein 6501 16751 27001
Re04.g04950 Putative uncharacterized protein 6502 16752 27002
Terpene synthase metal binding
Re04.g04960 domain protein 6503 16753 27003
Re04.g04970 Putative uncharacterized protein 6504 16754 27004
Re04.g04980 Putative fad dependent protein 6505 16755 27005 31695 33185
Re04.g04990 hypothetical protein 6506 16756 27006 31696 33186
Putative c6 zinc finger domain
Re04.g05000 protein 6507 16757 27007
Re04.g05010 Putative uncharacterized protein 6508 16758 27008
Re04.g05020 Putative uncharacterized protein 6509 16759 27009
Re04.g05030 Putative uncharacterized protein 6510 16760 27010 31697 33187
Re04.g05040 Putative uncharacterized protein 651 1 16761 2701 1 31698 33188
CCR4-NOT transcription complex
Re04.g05050 subunit 7 6512 16762 27012
Function: Tto1 can transpose
autonomously through reverse
transcription EC=2.7.7.49
EC=2.7.7.49 EC=2.7.7.49
Re04.g05060 EC=2.7.7.49 6513 16763 27013
Re04.g05070 Putative uncharacterized protein 6514 16764 27014 31699 33189
Re04.g05080 hypothetical protein 6515 16765 27015
Re04.g05090 Putative uncharacterized protein 6516 16766 27016
Re04.g05100 C6 zinc finger domain protein 6517 16767 27017
Protein-tyrosine phosphatase,
Re04.g051 10 putative 6518 16768 27018
Re04.g05120 hypothetical protein 6519 16769 27019 31700 33190
Re04.g05130 Uncharacterized protein 6520 16770 27020
Re04.g05140 Glutathione peroxidase 6521 16771 27021
Recombination hotspot-binding
Re04.g05150 protein (Translin), putative 6522 16772 27022
Re04.g05160 Pre-mRNA splicing factor Dim1 6523 16773 27023
Re04.g05170 60S ribosomal protein L22, putative 6524 16774 27024
Re04.g05180 RNA exonuclease Rex3, putative 6525 16775 27025 31701 33191
Re04.g05190 Lipase/serine esterase, putative 6526 16776 27026
Re04.g05200 Pc22g15180 protein 6527 16777 27027
Re04.g05210 Propionyl-CoA carboxylase 6528 16778 27028
Re04.g05220 Phosphatidyl synthase 6529 16779 27029
Re04.g05230 Putative uncharacterized protein 6530 16780 27030 31702 33192 Re04.g05240 Putative uncharacterized protein 6531 16781 27031
V-type ATPase, C subunit family
Re04.g05250 protein 6532 16782 27032
Re04.g05260 DUF1713 domain protein 6533 16783 27033 31703 33193
G protein complex alpha subunit
Re04.g05270 GanA 6534 16784 27034
Re04.g05280 Predicted protein 6535 16785 27035
Guanine nucleotide exchange
Re04.g05300 factor, putative 6536 16786 27036
Re04.g05310 DIL and Ankyrin domain protein 6537 16787 27037
Re04.g05320 hypothetical protein 6538 16788 27038
Re04.g05330 Uncharacterized protein 6539 16789 27039
Re04.g05340 Putative uncharacterized protein 6540 16790 27040
Re04.g05350 Putative uncharacterized protein 6541 16791 27041
Elongation of fatty acids protein,
Re04.g05360 putative 6542 16792 27042
Re04.g05370 Cytochrome P450, putative 6543 16793 27043 31704 33194
Re04.g05380 TBC domain protein, putative 6544 16794 27044
Conidiophore development protein
Re04.g05390 HymA 6545 16795 27045
S-adenosylmethionine-dependent
methyltransferase superfamily
Re04.g05400 domain-containing protein 6546 16796 27046
Re04.g05410 Uncharacterized protein 6547 16797 27047
Re04.g05420 Vesicular fusion ATPase, putative 6548 16798 27048
Re04.g05430 hypothetical protein 6549 16799 27049
Re04.g05440 Uncharacterized protein 6550 16800 27050
Re04.g05450 hypothetical protein 6551 16801 27051
Sensor histidine kinase/response
Re04.g05460 regulator, putative 6552 16802 27052
Sensor histidine kinase/response
Re04.g05470 regulator, putative 6553 16803 27053
Re04.g05480 Allantoicase Ale, putative 6554 16804 27054
Re04.g05490 Seryl-tRNA synthetase 6555 16805 27055
Re04.g05500 Cytochrome b561 6556 16806 27056
Re04.g05510 Putative uncharacterized protein 6557 16807 27057
Re04.g05520 hypothetical protein 6558 16808 27058
C6 finger domain protein Acr-2,
Re04.g05530 putative 6559 16809 27059
Serine/threonine protein kinase,
Re04.g05540 putative 6560 16810 27060
Re04.g05550 hypothetical protein 6561 1681 1 27061
Re04.g05560 Putative uncharacterized protein 6562 16812 27062
Re04.g05570 DUF250 domain membrane protein 6563 16813 27063
Re04.g05580 Putative uncharacterized protein 6564 16814 27064
Transcription initiation factor
Re04.g05590 TFIIIB, Brf1 subunit 6565 16815 27065
Copper resistance-associated P-
Re04.g05600 type ATPase, putative 6566 16816 27066 Re04.g05610 Endonuclease MUS81 6567 16817 27067
Re04.g05620 Uncharacterized protein 6568 16818 27068 31705 33195
Re04.g05630 C6 transcription factor, putative 6569 16819 27069
Re04.g05640 hypothetical protein 6570 16820 27070
Re04.g05650 Uncharacterized protein 6571 16821 27071
Clathrin-coated vesiclec protein
Re04.g05660 (Bud7), putative 6572 16822 27072
Re04.g05670 Histone transcription regulator 3 6573 16823 27073
Re04.g05680 Kinesin family protein 6574 16824 27074
Re04.g05690 Uncharacterized protein 6575 16825 27075
Re04.g05700 Ubiquitin conjugating enzyme 6576 16826 27076
Re04.g05710 Uncharacterized protein 6577 16827 27077
T-complex protein 1 , gamma
Re04.g05720 subunit, putative 6578 16828 27078
Zn-dependent
hydrolase/oxidoreductase family
Re04.g05730 protein, putative 6579 16829 27079 31706 33196
Mitochondrial chaperone BCS1 ,
Re04.g05740 putative 6580 16830 27080
Re04.g05750 hypothetical protein 6581 16831 27081 31707 33197
Re04.g05760 Predicted protein 6582 16832 27082 31708 33198
GTPase activating protein (Gyp3),
Re04.g05770 putative 6583 16833 27083
Re04.g05780 hypothetical protein 6584 16834 27084 31709 33199
Re04.g05790 Predicted protein 6585 16835 27085
Re04.g05800 Conserved proline-rich protein 6586 16836 27086
Re04.g05810 Uncharacterized protein 6587 16837 27087
Re04.g05820 Uncharacterized protein 6588 16838 27088
Re04.g05830 Putative uncharacterized protein 6589 16839 27089
Signal peptidase complex catalytic
Re04.g05840 subunit sec1 1 EC=3.4.21.89 6590 16840 27090 31710 33200
Re04.g05850 Uncharacterized protein 6591 16841 27091
Re04.g05860 Putative uncharacterized protein 6592 16842 27092
Re04.g05870 Uncharacterized protein 6593 16843 27093
Re04.g05880 Putative uncharacterized protein 6594 16844 27094
Re04.g05890 hypothetical protein 6595 16845 27095
Re04.g05900 Uncharacterized protein 6596 16846 27096
Re04.g05910 Uncharacterized protein 6597 16847 27097
Re04.g05920 Putative uncharacterized protein 6598 16848 27098
Extracellular serine-threonine rich
Re04.g05930 protein 6599 16849 27099 3171 1 33201
Re04.g05940 Uncharacterized protein 6600 16850 27100
Re04.g05950 hypothetical protein 6601 16851 27101 31712 33202
Re04.g05960 Putative uncharacterized protein 6602 16852 27102
Re04.g05970 Predicted protein 6603 16853 27103
Re04.g05980 Methyltransferase, putative 6604 16854 27104
Deacetylase complex subunit
Re04.g05990 Sds3, putative 6605 16855 27105
Re04.g06000 Similar to An02g09030 6606 16856 27106 Re04.g06010 Putative uncharacterized protein 6607 16857 27107
Cytochrome P450 oxidoreductase,
Re04.g06020 putative 6608 16858 27108
Re04.g06030 Putative uncharacterized protein 6609 16859 27109
1 ,3-beta-glucanosyltransferase,
Re04.g06040 putative 6610 16860 271 10 31713 33203
Protein kinase domain-containing
Re04.g06050 protein 661 1 16861 271 1 1
Re04.g06060 AT DNA binding protein, putative 6612 16862 271 12
Re04.g06080 Actin-related protein R07, putative 6613 16863 271 13
Re04.g06090 Rad2-like endonuclease, putative 6614 16864 271 14
Phosphatidate cytidylyltransferase
Re04.g06100 family protein 6615 16865 271 15
ATP-dependent rRNA helicase
Re04.g061 10 spb4 6616 16866 271 16
Re04.g06120 hypothetical protein 6617 16867 271 17
Re04.g06130 Putative uncharacterized protein 6618 16868 271 18
Re04.g06140 Ribosomal protein S15, putative 6619 16869 271 19
Re04.g06150 40S ribosomal protein SO 6620 16870 27120
Re04.g06160 Uncharacterized protein 6621 16871 27121
Re04.g06170 Rho-like small GTPase, putative 6622 16872 27122
Re04.g06180 Pseudouridylate synthase 3 6623 16873 27123
Re04.g06190 Putative uncharacterized protein 6624 16874 27124 31714 33204
Re04.g06200 Ubiquitin-like modifier HUB1 6625 16875 27125
Ribose-phosphate
Re04.g06210 pyrophosphokinase 6626 16876 27126
Vacuolar ATP synthase subunit d,
Re04.g06220 putative EC=3.6.3.14 6627 16877 27127
Re04.g06230 Nucleolar protein 58 6628 16878 27128
Re04.g06240 Uncharacterized protein Fragment 6629 16879 27129
Re04.g06250 Uncharacterized protein 6630 16880 27130
Re04.g06260 Uncharacterized protein 6631 16881 27131
Re04.g06270 Ubiquitin conjugating enzyme 6632 16882 27132
Re04.g06280 Stomatin family protein 6633 16883 27133
Pathogenesis associated protein
Re04.g06290 Cap20, putative 6634 16884 27134
Re04.g06300 hypothetical protein 6635 16885 27135
Re04.g06310 hypothetical protein 6636 16886 27136
Re04.g06320 60S ribosomal protein L27 6637 16887 27137
Re04.g06330 Predicted protein 6638 16888 27138
Re04.g06340 Uncharacterized protein 6639 16889 27139
Re04.g06350 DUF887 domain protein 6640 16890 27140
Re04.g06360 SWI-SNF complex subunit 6641 16891 27141
Proteasome regulatory particle
Re04.g06370 subunit (RpnF), putative 6642 16892 27142
Small nucleolar ribonucleoprotein
Re04.g06380 complex subunit 6643 16893 27143
Short-chain
Re04.g06390 dehydrogenase/reductase family 6644 16894 27144 protein, putative
Re04.g06400 PHD finger domain protein 6645 16895 27145
Re04.g06410 Uncharacterized protein 6646 16896 27146
Re04.g06420 Riboflavin synthase, alpha subunit 6647 16897 27147
Re04.g06430 Uncharacterized protein 6648 16898 27148
ATP-dependent rRNA helicase rrp3
Re04.g06440 EC=3.6.4.- 6649 16899 27149
Re04.g06450 Phosphoacetylglucosamine mutase 6650 16900 27150
Re04.g06460 Uncharacterized protein 6651 16901 27151 31715 33205
Histone H4 arginine
Re04.g06470 methyltransferase RmtA 6652 16902 27152
Re04.g06480 Putative uncharacterized protein 6653 16903 27153
Trimethyllysine dioxygenase,
Re04.g06490 putative 6654 16904 27154
Proteasome regulatory particle
Re04.g06500 subunit Rpt5, putative 6655 16905 27155
Re04.g06510 Uncharacterized protein 6656 16906 27156
Re04.g06520 hypothetical protein 6657 16907 27157
cAMP-dependent protein kinase-
Re04.g06530 like, putative EC=2.7.1 1.13 6658 16908 27158
Re04.g06540 Nuclear localization protein NPL6 6659 16909 27159
Re04.g06550 hypothetical protein 6660 16910 27160
Re04.g06560 Cyclin-like protein 6661 1691 1 27161
Phosphoglycerate mutase family
Re04.g06570 domain protein 6662 16912 27162 31716 33206
Re04.g06580 Dor1 -like family protein 6663 16913 27163
Re04.g06590 Putative uncharacterized protein 6664 16914 27164
Re04.g06600 Cyclin, putative 6665 16915 27165
Re04.g06610 Uncharacterized protein 6666 16916 27166
Ubiquinone/menaquinone
Re04.g06620 biosynthesis-related protein 6667 16917 27167
Fructosyl amino acid
Re04.g06630 oxidasesarcosine oxidase, putative 6668 16918 27168 31717 33207
RNA polymerase I and III
transcription factor complex
Re04.g06640 component Tbp, putative 6669 16919 27169
Electron transfer flavoprotein-
Re04.g06650 ubiquinone oxidoreductase 6670 16920 27170
Pre-RNA splicing factor Srp2,
Re04.g06660 putative 6671 16921 27171
Dihydroneopterin aldolase domain
Re04.g06670 protein 6672 16922 27172
Serine/threonine protein kinase,
Re04.g06680 putative 6673 16923 27173
Re04.g06690 Uncharacterized protein 6674 16924 27174
Re04.g06710 hypothetical protein 6675 16925 27175 31718 33208
Re04.g06720 hypothetical protein 6676 16926 27176
Re04.g06730 Uncharacterized protein 6677 16927 27177
Re04.g06740 Peroxisomal membrane anchor 6678 16928 27178 31719 33209 protein (Pex14), putative
Re04.g06750 Putative uncharacterized protein 6679 16929 27179
ATP-binding cassette transporter,
Re04.g06760 putative EC=3.6.3.44 6680 16930 27180 31720 33210
Re04.g06770 Acid phosphatase, putative 6681 16931 27181
Re04.g06780 Putative uncharacterized protein 6682 16932 27182
Ccr4-Not transcription complex
Re04.g06790 subunit 6683 16933 27183
Cell division control protein
Re04.g06800 (Cdc15), putative 6684 16934 27184
Re04.g06810 hypothetical protein 6685 16935 27185
Re04.g06820 hypothetical protein 6686 16936 27186
Re04.g06830 UPF0132 domain protein 6687 16937 27187
DASH complex subunit Duo1 ,
putative (AFU orthologue
Re04.g06840 AFUA_3G10260) 6688 16938 27188
Re04.g06850 Uncharacterized protein 6689 16939 27189
Re04.g06860 DNA replication protein, putative 6690 16940 27190
Re04.g06870 Uncharacterized protein 6691 16941 27191
Re04.g06880 Galactokinase 6692 16942 27192
Re04.g06890 Acetolactate synthase EC=2.2.1.6 6693 16943 27193 31721 3321 1
Re04.g06900 RING finger domain protein 6694 16944 27194
Re04.g06910 Putative uncharacterized protein 6695 16945 27195 31722 33212
Function: Rho2 GTPase regulates
the synthesis of alpha-D-glucan
Re04.g06920 EC=1.1.1.15 6696 16946 27196
Re04.g06930 Stress response protein NST1 6697 16947 27197
Vacuolar protein sorting-associated
Re04.g06940 protein 35 6698 16948 27198
C6 transcription factor GliZ-like,
Re04.g06950 putative 6699 16949 27199
Re04.g06960 hypothetical protein 6700 16950 27200
Re04.g06970 Uncharacterized protein 6701 16951 27201
7-dimethylallyltryptophan synthase
Re04.g06980 EC=2.5.1.80 EC=3.4.1 1.17 6702 16952 27202
Re04.g06990 MFS transporter, putative 6703 16953 27203
Nitrogen assimilation transcription
Re04.g07000 factor NirA 6704 16954 27204
Similarity to unknown aldolases
Re04.g07010 and adducins EC=1 6705 16955 27205
Re04.g07020 Uncharacterized protein Fragment 6706 16956 27206
Re04.g07030 Uncharacterized protein 6707 16957 27207
Re04.g07040 Uncharacterized protein 6708 16958 27208 31723 33213
Re04.g07050 Uncharacterized protein 6709 16959 27209
Succinate
dehydrogenase/fumarate
Re04.g07060 reductase, flavoprotein subunit 6710 16960 27210 31724 33214
Re04.g07070 hypothetical protein 671 1 16961 2721 1
Re04.g07080 FAD dependent oxidoreductase, 6712 16962 27212 31725 33215 putative
Re04.g07090 MFS sugar transporter, putative 6713 16963 27213
Re04.g07100 DnaJ and TPR domain protein 6714 16964 27214
Re04.g071 10 Uncharacterized protein Fragment 6715 16965 27215
Re04.g07120 hypothetical protein 6716 16966 27216
Re04.g07130 Putative uncharacterized protein 6717 16967 27217
Re04.g07140 Putative uncharacterized protein 6718 16968 27218
Re04.g07150 Putative uncharacterized protein 6719 16969 27219
Re04.g07160 Tannase/feruloyl esterase 6720 16970 27220
Function: PVA is used for the
enzymatic hydrolysis of penicillin V
Re04.g07170 EC=3.1 Precursor 6721 16971 27221 31726 33216
Re04.g07180 hypothetical protein 6722 16972 27222 31727 33217
MAP kinase kinase (Mkk2),
Re04.g07190 putative 6723 16973 27223
Re04.g07200 Protein transport protein Sec39 6724 16974 27224 31728 33218
Re04.g07210 Uncharacterized protein 6725 16975 27225
Re04.g07220 Predicted protein 6726 16976 27226
TBP associated factor (Mot1 ),
Re04.g07230 putative 6727 16977 27227
Re04.g07240 Putative uncharacterized protein 6728 16978 27228
Re04.g07250 Erythromycin esterase, putative 6729 16979 27229
Re04.g07260 Putative uncharacterized protein 6730 16980 27230
Inositol phospholipid biosynthesis
Re04.g07270 protein Scs3, putative 6731 16981 27231
Re04.g07280 Beta-glucosidase 6732 16982 27232 31729 33219
Re04.g07290 Uncharacterized protein 6733 16983 27233
Re04.g07300 Putative uncharacterized protein 6734 16984 27234
Short chain
Re04.g07310 dehydrogenase/reductase, putative 6735 16985 27235
Re04.g07320 C6 transcription factor, putative 6736 16986 27236
Vacuolar sorting receptor (Mrl1 ),
Re04.g07330 putative 6737 16987 27237 31730 33220
Function: the erg-3 protein from N.
crassa reduces the C14=C15
Re04.g07340 double bond of 4 EC=1.1.-.- 6738 16988 27238
Re04.g07350 Putative uncharacterized protein 6739 16989 27239
Re04.g07360 Uncharacterized protein 6740 16990 27240
Re04.g07370 Putative uncharacterized protein 6741 16991 27241 31731 33221
Re04.g07380 Uncharacterized protein 6742 16992 27242 31732 33222
Re04.g07390 hypothetical protein 6743 16993 27243
Re04.g07400 Putative uncharacterized protein 6744 16994 27244
Splicing factor 3B subunit 10
Re04.g07410 (SF3b10), putative 6745 16995 27245
TRNA-specific adenosine
Re04.g07420 deaminase, putative 6746 16996 27246
Re04.g07430 Putative uncharacterized protein 6747 16997 27247
Re04.g07440 Protein phosphatase 6748 16998 27248
Re04.g07450 40S ribosomal protein S3, putative 6749 16999 27249 Phenylalanyl-tRNA synthetase,
Re04.g07460 beta subunit 6750 17000 27250
Protein phosphatase PP2A
Re04.g07470 regulatory subunit A 6751 17001 27251
Re04.g07480 Putative uncharacterized protein 6752 17002 27252
Capsule-associated protein CAP1 ,
Re04.g07490 putative 6753 17003 27253 31733 33223
Re04.g07500 Glycogenin 6754 17004 27254
Re04.g07510 Cysteine dioxygenase 6755 17005 27255
Re04.g07520 GTP binding protein, putative 6756 17006 27256
Re04.g07530 Putative uncharacterized protein 6757 17007 27257
Re04.g07540 Uncharacterized protein 6758 17008 27258
Re04.g07550 PXA domain protein 6759 17009 27259
Re04.g07560 Uncharacterized protein 6760 17010 27260
Mandelate racemase/muconate
lactonizing enzyme family protein
Re04.g07570 EC=4.2.1.6 6761 1701 1 27261
Re04.g07580 Uncharacterized protein 6762 17012 27262
Re04.g07590 40S ribosomal protein S12 6763 17013 27263
Histone deacetylase complex
Re04.g07600 subunit (Hos4), putative 6764 17014 27264 31734 33224
3-oxo-5-alpha-steroid 4-
Re04.g07610 dehydrogenase, putative 6765 17015 27265 31735 33225
Re04.g07620 Putative uncharacterized protein 6766 17016 27266
Re04.g07630 Peptidyl-prolyl cis-trans isomerase 6767 17017 27267
Similarity to hypothetical protein
Re04.g07640 CAD1 1794.1 6768 17018 27268
Re04.g07650 Uncharacterized protein 6769 17019 27269
UDP-Glc/Gal endoplasmic
reticulum nucleotide sugar
Re04.g07660 transporter 6770 17020 27270
Re04.g07670 Uncharacterized protein 6771 17021 27271 31736 33226
Re04.g07680 Transcription factor SipA3, putative 6772 17022 27272
Re04.g07690 Ribosome biogenesis protein Kri1 6773 17023 27273
UMTA methyltransferase family
Re04.g07700 protein 6774 17024 27274
Re04.g07710 ADP/ATP carrier protein 6775 17025 27275
Re04.g07720 hypothetical protein 6776 17026 27276
Re04.g07730 Putative uncharacterized protein 6777 17027 27277 31737 33227
Re04.g07740 CAIB/BAIF family enzyme 6778 17028 27278
Re04.g07750 Uncharacterized protein 6779 17029 27279
Re04.g07760 Putative uncharacterized protein 6780 17030 27280
Re04.g07770 Alpha/beta hydrolase, putative 6781 17031 27281
Re04.g07780 Catechol dioxygenase, putative 6782 17032 27282
tRNA splicing 2'
Re04.g07790 phosphotransferase 1 6783 17033 27283
Re04.g07800 Uncharacterized protein 6784 17034 27284
Re04.g07810 rRNA-processing protein efgl 6785 17035 27285
Re04.g07820 F-box domain protein 6786 17036 27286 Serine/threonine protein kinase,
Re04.g07830 putative 6787 17037 27287
Re04.g07840 TBC domain protein, putative 6788 17038 27288
Re04.g07850 Putative uncharacterized protein 6789 17039 27289
Alcohol dehydrogenase, zinc-
Re04.g07860 containing, putative 6790 17040 27290
Re04.g07870 KH domain RNA-binding protein 6791 17041 27291
Re04.g07880 Predicted protein 6792 17042 27292
Re04.g07890 Predicted protein 6793 17043 27293
Re04.g07900 Putative uncharacterized protein 6794 17044 27294 31738 33228
Re04.g07910 hypothetical protein 6795 17045 27295 31739 33229
Re04.g07920 hypothetical protein 6796 17046 27296
Re04.g07930 Equisetin synthetase, putative 6797 17047 27297
Re04.g07940 Uncharacterized protein 6798 17048 27298
Re04.g07950 O-methyltransferase, putative 6799 17049 27299
Aspartate aminotransferase
Re04.g07960 EC=2.6.1.1 6800 17050 27300
Re04.g07970 Uncharacterized protein 6801 17051 27301
Re04.g07980 Uncharacterized protein 6802 17052 27302
Re04.g07990 Uncharacterized protein 6803 17053 27303
Re04.g08000 Uncharacterized protein 6804 17054 27304
Re04.g08010 Putative uncharacterized protein 6805 17055 27305
Re04.g08020 Putative uncharacterized protein 6806 17056 27306
Re04.g08030 hypothetical protein 6807 17057 27307 31740 33230
Re04.g08040 hypothetical protein 6808 17058 27308
Protein-tyrosine phosphatase,
Re04.g08050 putative 6809 17059 27309
S-adenosylmethionine-dependent
Re04.g08060 methyltransferase, putative 6810 17060 27310
Re04.g08070 Uncharacterized protein 681 1 17061 2731 1
Re04.g08080 Protein yippee-like 6812 17062 27312 31741 33231
C2H2 finger domain protein,
Re04.g08090 putative 6813 17063 27313 31742 33232
Re04.g08100 Putative uncharacterized protein 6814 17064 27314 31743 33233
Ribosome biogenesis protein
Re04.g081 10 RLP24 6815 17065 27315
Mitochondrial DnaJ chaperone
Re04.g08120 (Tim14), putative 6816 17066 27316 31744 33234
Fungal specific transcription factor
Re04.g08130 domain protein 6817 17067 27317
Respiratory chain complexes
Re04.g08140 assembly protein real 6818 17068 27318 31745 33235
Re04.g08150 DUF1295 domain protein 6819 17069 27319
Re04.g08160 DNA topoisomerase EC=5.99.1.2 6820 17070 27320
Re04.g08170 hypothetical protein 6821 17071 27321 31746 33236
Re04.g08180 MFS sugar transporter, putative 6822 17072 27322
Re04.g08190 hypothetical protein 6823 17073 27323 31747 33237
Re04.g08200 Uncharacterized protein 6824 17074 27324
Re04.g08210 Ku family DNA helicase, putative 6825 17075 27325 SNARE complex subunit (Vam7),
Re04.g08220 putative 6826 17076 27326
Re04.g08230 Putative uncharacterized protein 6827 17077 27327
Re04.g08240 Uncharacterized protein 6828 17078 27328
Aspartyl-tRNA synthetase Dps1 ,
Re04.g08250 putative 6829 17079 27329
HAD superfamily hydrolase,
Re04.g08260 putative 6830 17080 27330
Re04.g08270 F-box domain protein 6831 17081 27331
Re04.g08280 Coatomer subunit gamma 6832 17082 27332
Re04.g08290 Phosducin family protein 6833 17083 27333
Re04.g08300 Uncharacterized protein 6834 17084 27334
Re04.g08310 Casein kinase I, putative 6835 17085 27335
Cell polarity protein (Teal ),
Re04.g08320 putative 6836 17086 27336
Meiotic regulator-interacting
Re04.g08330 protein, putative 6837 17087 27337
Re04.g08340 Uncharacterized protein 6838 17088 27338
Re04.g08350 Uncharacterized protein 6839 17089 27339 31748 33238
Re04.g08360 Putative uncharacterized protein 6840 17090 27340 31749 33239
Re04.g08370 hypothetical protein 6841 17091 27341
Re04.g08380 Uncharacterized protein 6842 17092 27342 31750 33240
Re04.g08390 Uncharacterized protein 6843 17093 27343
Re04.g08400 Uncharacterized protein 6844 17094 27344
Leucine Rich Repeat domain
Re04.g08410 protein 6845 17095 27345
Re04.g08420 hypothetical protein 6846 17096 27346 31751 33241
Mitochondrial genome
Re04.g08430 maintenance protein Mgr2, putative 6847 17097 27347
Cytoplasm to vacuole targeting
Re04.g08440 Vps64, putative 6848 17098 27348
Re04.g08450 Uncharacterized protein 6849 17099 27349
Re04.g08460 Uncharacterized protein 6850 17100 27350 31752 33242
Re04.g08470 Putative uncharacterized protein 6851 17101 27351
Re04.g08480 UDP-glucose 6852 17102 27352
Re04.g08490 Uncharacterized protein 6853 17103 27353
Re04.g08500 MYB DNA-binding domain protein 6854 17104 27354
Re04.g08510 Pc12g 16300 protein 6855 17105 27355
Re04.g08520 Hsp70 chaperone (BiP), putative 6856 17106 27356
Actin cortical patch protein Sur7,
Re04.g08530 putative 6857 17107 27357
Re04.g08540 Uncharacterized protein 6858 17108 27358
Re04.g08550 37S ribosomal protein Rsm22 6859 17109 27359
Mitotic spindle biogenesis protein
Re04.g08560 Spc19, putative 6860 171 10 27360
Re04.g08570 Predicted protein 6861 171 1 1 27361 31753 33243
Re04.g08580 Uncharacterized protein 6862 171 12 27362
Allantoinase Dal1 , putative
Re04.g08590 EC=3.5.2.5 6863 171 13 27363 Re04.g08600 Putative uncharacterized protein 6864 171 14 27364 31754 33244
Re04.g08610 Prefoldin subunit 3 6865 171 15 27365
Eukaryotic translation initiation
Re04.g08620 factor 3 subunit K 6866 171 16 27366
Re04.g08630 Uncharacterized protein 6867 171 17 27367
Re04.g08640 Uncharacterized protein Fragment 6868 171 18 27368
Re04.g08650 Uncharacterized protein 6869 171 19 27369 31755 33245
Re04.g08660 PDCD2_C domain protein, putative 6870 17120 27370
Re04.g08670 Prenylcysteine lyase 6871 17121 27371 31756 33246
UDP-glucose:sterol
Re04.g08680 glycosyltransferase EC=2.4.1.173 6872 17122 27372
Serine hydroxymethyltransferase,
Re04.g08690 cytosolic, putative 6873 17123 27373
Re04.g08700 Uncharacterized protein 6874 17124 27374
Phosphoglycerate mutase, 2,3-
Re04.g08710 bisphosphoglycerate-independent 6875 17125 27375
Re04.g08720 KE2 family protein 6876 17126 27376
Vacuolar sorting ATPase Vps4,
Re04.g08730 putative 6877 17127 27377
Spindle-pole body protein (Pcp1 ),
Re04.g08740 putative 6878 17128 27378
Re04.g08750 Regulatory factor Sgt1 6879 17129 27379
Re04.g08760 AMMECR1 family protein 6880 17130 27380
Calcium/calmodulin dependent
Re04.g08770 protein kinase, putative 6881 17131 27381
Re04.g08780 hypothetical protein 6882 17132 27382
Re04.g08790 Putative uncharacterized protein 6883 17133 27383
Re04.g08800 DNA polymerase EC=2.7.7.7 6884 17134 27384
Cytochrome c oxidase protein 20,
Re04.g08810 mitochondrial 6885 17135 27385
Re04.g08820 Putative uncharacterized protein 6886 17136 27386
Pre-rRNA processing nucleolar
Re04.g08830 protein Sik1 , putative 6887 17137 27387
T-complex protein 1 , zeta subunit,
Re04.g08840 putative 6888 17138 27388
Histone acetyltransferase (MysT1 ),
Re04.g08850 putative 6889 17139 27389
Re04.g08860 RNA binding protein, putative 6890 17140 27390
Re04.g08870 Pc12g15910 protein 6891 17141 27391
Camp independent regulatory
Re04.g08880 protein 6892 17142 27392
Re04.g08890 Uncharacterized protein 6893 17143 27393 31757 33247
Re04.g08900 Uncharacterized protein 6894 17144 27394
Re04.g08910 Uncharacterized protein 6895 17145 27395 31758 33248
Re04.g08920 Pre-mRNA-splicing factor cwc24 6896 17146 27396
Nuclear migration protein (ApsA),
Re04.g08930 putative 6897 17147 27397
Re04.g08940 Putative uncharacterized protein 6898 17148 27398 31759 33249
Re04.g08950 Uncharacterized protein 6899 17149 27399 Re04.g08960 SH3 domain signalling protein 6900 17150 27400
Re04.g08970 Putative uncharacterized protein 6901 17151 27401
Re04.g08980 Uncharacterized protein 6902 17152 27402
RNA 3'-terminal phosphate
Re04.g08990 cyclase, putative 6903 17153 27403
Re04.g09000 Putative c6 transcription protein 6904 17154 27404
Re04.g09010 Uncharacterized protein 6905 17155 27405
Re04.g09020 hypothetical protein 6906 17156 27406
Re04.g09030 MFS multidrug transporter 6907 17157 27407
Re04.g09040 Inositol 5-phosphatase, putative 6908 17158 27408
Re04.g09050 AMP dependent CoA ligase 6909 17159 27409
Re04.g09060 Putative uncharacterized protein 6910 17160 27410 31760 33250
Oxidoreductase, short-chain
Re04.g09070 dehydrogenase/reductase family 691 1 17161 2741 1
Re04.g09080 Uncharacterized protein 6912 17162 27412 31761 33251
GTPase activating protein (Gyp2),
Re04.g09090 putative 6913 17163 27413
Rho guanyl nucleotide exchange
Re04.g09100 factor, putative 6914 17164 27414
Re04.g091 10 Uncharacterized protein 6915 17165 27415
Re04.g09120 Phenylacetyl-CoA ligase, putative 6916 17166 27416
Re04.g09130 Putative uncharacterized protein 6917 17167 27417
NADH-ubiquinone oxidoreductase
Re04.g09140 B12 subunit, putative 6918 17168 27418
CCR4-NOT core complex subunit
Re04.g09150 Ca l , putative 6919 17169 27419
Re04.g09160 Uncharacterized protein 6920 17170 27420
Re04.g09170 Amine oxidase 6921 17171 27421
Re04.g09180 Putative uncharacterized protein 6922 17172 27422
Re04.g09190 hypothetical protein 6923 17173 27423
Re04.g09200 Putative uncharacterized protein 6924 17174 27424
Re04.g09210 Putative uncharacterized protein 6925 17175 27425
Re04.g09220 Catechol O-methyltransferase 6926 17176 27426
NAD binding Rossmann fold
Re04.g09230 oxidoreductase, putative 6927 17177 27427
Re04.g09240 HPP family protein 6928 17178 27428
ATP-binding cassette sub-family F
Re04.g09250 member 2 6929 17179 27429
Proteasome regulatory particle
Re04.g09260 subunit Rpt2, putative 6930 17180 27430
Ubiquitin-conjugating enzyme,
Re04.g09270 putative 6931 17181 27431
Re04.g09280 Cyclin Cel l , putative 6932 17182 27432
Re04.g09290 WD repeat protein 6933 17183 27433
Re04.g09300 DUF803 domain membrane protein 6934 17184 27434
Probable xyloglucan-specific endo- beta-1 ,4-glucanase A
Re04.g09310 EC=3.2.1.151 Precursor 6935 17185 27435 31762 33252
Re04.g09330 Putative uncharacterized protein 6936 17186 27436 Re04.g09340 Uncharacterized protein 6937 17187 27437
Re04.g09350 GRAM domain protein 6938 17188 27438
Re04.g09360 Integral membrane protein 6939 17189 27439
Re04.g09370 RNP domain protein 6940 17190 27440
Re04.g09380 Zinc finger protein gcsl 6941 17191 27441
Re04.g09390 Ribosome-releasing factor 2 6942 17192 27442
Vacuolar protein sorting-associated
Re04.g09400 protein vps17 6943 17193 27443
Re04.g09410 Uncharacterized protein 6944 17194 27444
Re04.g09420 Predicted protein 6945 17195 27445
Ctr copper transporter family
Re04.g09430 protein 6946 17196 27446 31763 33253
Re04.g09440 Putative uncharacterized protein 6947 17197 27447
Re04.g09450 hypothetical protein 6948 17198 27448
Re04.g09460 Phosphate transporter 6949 17199 27449
Re04.g09470 hypothetical protein 6950 17200 27450
Re04.g09480 Putative uncharacterized protein 6951 17201 27451
Re04.g09490 Uncharacterized protein 6952 17202 27452
Re04.g09500 Tho2 protein 6953 17203 27453
Homoserine O-acetyltransferase,
Re04.g09510 putative EC=2.3.1.175 6954 17204 27454
Re04.g09520 hypothetical protein 6955 17205 27455
Re04.g09530 SAP domain-containing protein 6956 17206 27456
Re04.g09540 DUF300 domain protein, putative 6957 17207 27457
COP9 signalosome subunit 6
Re04.g09550 (CsnF), putative 6958 17208 27458
Re04.g09560 Putative uncharacterized protein 6959 17209 27459
Re04.g09570 Putative uncharacterized protein 6960 17210 27460
NADPH-dependent FMN/FAD
Re04.g09580 containing oxidoreductase, putative 6961 1721 1 27461
Re04.g09590 Alpha-amylase 6962 17212 27462 31764 33254
Alpha-1 ,3-glucan synthase,
Re04.g09600 putative 6963 17213 27463 31765 33255
Re04.g09610 Carboxypeptidase S1 , putative 6964 17214 27464 31766 33256
Poly polymerase (Poly[ADP-ribose]
Re04.g09620 synthetase) 6965 17215 27465
Re04.g09630 DUF500 domain protein 6966 17216 27466
Electron transfer flavoprotein, beta
subunit, putative (AFU orthologue
Re04.g09640 AFUA_5G07300) 6967 17217 27467
Re04.g09650 Molecular chaperone 6968 17218 27468
Re04.g09660 Putative uncharacterized protein 6969 17219 27469
Carbamoyl-phosphate synthase,
Re04.g09670 small subunit EC=6.3.5.5 6970 17220 27470
GTP binding protein (Gtp1 ),
Re04.g09680 putative 6971 17221 27471
Cell cycle control protein (Cwf2),
Re04.g09690 putative 6972 17222 27472
Re04.g09700 Protein kinase (Gcn2), putative 6973 17223 27473 Re04.g09710 Uncharacterized protein 6974 17224 27474
Re04.g09720 Uncharacterized protein 6975 17225 27475
Serine/threonine-protein
Re04.g09730 phosphatase EC=3.1.3.16 6976 17226 27476
Transcription elongation factor
Re04.g09740 SPT4 6977 17227 27477
Re04.g09750 4-aminobutyrate aminotransferase 6978 17228 27478
Re04.g09760 Integral membrane protein 6979 17229 27479
Re04.g09770 Putative uncharacterized protein 6980 17230 27480
Re04.g09780 Pc21 g17830 protein 6981 17231 27481
Re04.g09790 MFS sugar transporter, putative 6982 17232 27482
Re04.g09800 hypothetical protein 6983 17233 27483
Re04.g09810 Predicted protein 6984 17234 27484
Re04.g09820 Putative uncharacterized protein 6985 17235 27485
Glutathione synthetase, putative
Re04.g09830 EC=6.3.2.3 6986 17236 27486
SNF2 family helicase/ATPase,
Re04.g09840 putative 6987 17237 27487
Re04.g09850 SNF2 family helicase 6988 17238 27488
Re04.g09860 Putative uncharacterized protein 6989 17239 27489
Re04.g09870 Uncharacterized protein 6990 17240 27490
Filamentation protein (Rh l ),
Re04.g09880 putative 6991 17241 27491
NADH-ubiquinone oxidoreductase
Re04.g09890 subunit B17.2 6992 17242 27492
Re04.g09900 Uncharacterized protein 6993 17243 27493
Low-temperature viability protein
Re04.g09910 Itv1 6994 17244 27494
Ribosome biogenesis GTPase
Re04.g09920 Lsg1 , putative 6995 17245 27495
Re04.g09930 Glycosyl transferase, putative 6996 17246 27496
Re04.g09940 UDP-glucose dehydrogenase 6997 17247 27497
Acyl-CoA dehydrogenase family
Re04.g09950 protein 6998 17248 27498
Re04.g09960 Function: in S. cerevisiae BNS1 6999 17249 27499
Re04.g09970 Sad1/UNC domain protein 7000 17250 27500 31767 33257
Serine/threonine protein kinase,
Re04.g09980 putative 7001 17251 27501
Re04.g09990 Uncharacterized protein 7002 17252 27502
Re04.g10000 C6 finger domain protein, putative 7003 17253 27503
Vacuolar protein sorting protein
Re04.g10010 DigA 7004 17254 27504
Re04.g 10020 50S ribosomal subunit L7, putative 7005 17255 27505
Ubiquitin C-terminal hydrolase
Re04.g10030 family protein 7006 17256 27506
Re04.g 10040 Beta-lactamase family protein 7007 17257 27507
Re04.g 10050 MAP kinase kinase kinase SteC 7008 17258 27508
Re04.g 10060 Elongation factor EF-2 7009 17259 27509
Re04.g10070 Putative uncharacterized protein 7010 17260 27510 Re04.g10080 hypothetical protein 701 1 17261 2751 1
Re04.g10090 Putative uncharacterized protein 7012 17262 27512
Re04.g10100 Putative uncharacterized protein 7013 17263 27513
C2H2 transcription factor (AmdA),
Re04.g101 10 putative 7014 17264 27514
Re04.g10120 Putative uncharacterized protein 7015 17265 27515
Re04.g10130 Uncharacterized protein 7016 17266 27516
Re04.g10140 Uncharacterized protein 7017 17267 27517
Re04.g10150 Putative uncharacterized protein 7018 17268 27518
Re04.g10160 60S ribosomal protein L8, putative 7019 17269 27519
DNA repair and transcription factor
Re04.g10170 Ada, putative EC=2.1.1.63 7020 17270 27520
Re04.g10180 BAR domain protein 7021 17271 27521
RSC complex subunit (Sth1 ),
Re04.g10190 putative 7022 17272 27522
Re04.g 10200 hypothetical protein 7023 17273 27523
Membrane biogenesis protein
Re04.g10210 (Yop1 ), putative 7024 17274 27524
Re04.g 10220 Putative uncharacterized protein 7025 17275 27525
Peroxisomal matrix protein
importer Pex3-Penicillium
Re04.g 10230 chrysogenum 7026 17276 27526
Re04.g 10240 MFS transporter, putative 7027 17277 27527
Re04.g 10250 Putative uncharacterized protein 7028 17278 27528
Re04.g 10260 Predicted protein 7029 17279 27529
5-aminolevulinic acid synthase
Re04.g 10270 HemA EC=2.3.1.37 7030 17280 27530
SNF2 family helicase/ATPase
Re04.g 10280 (Ino80), putative 7031 17281 27531
Re04.g 10290 Alcohol dehydrogenase 7032 17282 27532
Re04.g10300 Sodium/hydrogen exchanger 7033 17283 27533 31768 33258
Re04.g10310 Transposase 7034 17284 27534
Re04.g 10320 Sucrose transporter, putative 7035 17285 27535
Sexual development transcription
Re04.g10330 factor SteA 7036 17286 27536
Re04.g 10340 hypothetical protein 7037 17287 27537
Re04.g 10350 Uncharacterized protein 7038 17288 27538
Re04.g 10360 5-proFAR isomerase 7039 17289 27539
Re04.g10370 hypothetical protein 7040 17290 27540
Re04.g10380 Putative uncharacterized protein 7041 17291 27541
Re04.g10390 Histone acetyltransferase 7042 17292 27542
Re04.g 10400 Succinyl-CoA ligase alpha-chain 7043 17293 27543
DNA damage and replication
Re04.g10410 checkpoint protein Rfx1 , putative 7044 17294 27544
Re04.g 10420 Uncharacterized protein 7045 17295 27545
Re04.g 10430 SUMO activating enzyme 7046 17296 27546
Integral membrane protein ( Ytp 1 ) ,
Re04.g 10440 putative 7047 17297 27547 31769 33259
Re04.g 10450 DNA repair protein Swi5/Sae3, 7048 17298 27548 putative
Re04.g 10460 ABC multidrug transporter Mdr1 7049 17299 27549
Re04.g 10470 hypothetical protein 7050 17300 27550
Probable RPL39-60S large subunit
Re04.g 10480 ribosomal protein L39.e 7051 17301 27551
E3 ubiquitin ligase complex SCF
Re04.g 10490 subunit sconC 7052 17302 27552
Re04.g 10500 Predicted protein 7053 17303 27553
Alpha 1 ,2-mannosyltransferase
Re04.g10510 Smp3, putative 7054 17304 27554 31770 33260
Nucleotide excision repair protein
Re04.g 10520 RAD23 7055 17305 27555
Re04.g 10530 Uncharacterized protein 7056 17306 27556
Eukaryotic translation initiation
Re04.g 10540 factor 6 7057 17307 27557
Re04.g 10550 SET and WW domain protein 7058 17308 27558
Re04.g 10560 hypothetical protein 7059 17309 27559
Re04.g 10570 Putative uncharacterized protein 7060 17310 27560
Calcium/calmodulin dependent
Re04.g 10580 protein kinase, putative 7061 1731 1 27561
Re04.g 10590 Uncharacterized protein 7062 17312 27562
Serine/threonine protein kinase,
Re04.g 10600 putative 7063 17313 27563 31771 33261
BAR adaptor protein RVS161 ,
Re04.g 10620 putative 7064 17314 27564
Re04.g 10630 Peptidyl-tRNA hydrolase, putative 7065 17315 27565 31772 33262
Re04.g 10640 Uncharacterized protein 7066 17316 27566
Re04.g 10650 RNA processing factor 1 7067 17317 27567
Re04.g 10660 Glycyl-tRNA synthetase 7068 17318 27568
Re04.g 10670 Putative uncharacterized protein 7069 17319 27569
Re04.g 10680 Protein kinase (Chm1 ), putative 7070 17320 27570
Mitochondrial NADH kinase POS5,
Re04.g 10690 putative 7071 17321 27571
Re04.g10700 Acyltransferase, putative 7072 17322 27572
RNA polymerase II transcription
Re04.g10710 elongation factor (Ctr9), putative 7073 17323 27573
Re04.g 10720 Homoserine kinase 7074 17324 27574
Re04.g10730 Uncharacterized protein 7075 17325 27575
Re04.g 10740 Calcium channel subunit Midi 7076 17326 27576 31773 33263
Re04.g 10750 Uncharacterized protein 7077 17327 27577
Re04.g 10760 Putative uncharacterized protein 7078 17328 27578
Re04.g10770 hypothetical protein 7079 17329 27579
Re04.g10780 hypothetical protein 7080 17330 27580
Re04.g10790 hypothetical protein 7081 17331 27581
Microsomal signal peptidase
Re04.g10800 Spc12, putative 7082 17332 27582
Ubiquitin ligase subunit HrtA,
Re04.g10810 putative 7083 17333 27583
Re04.g 10820 Uncharacterized protein 7084 17334 27584 1 ,3-beta-glucan biosynthesis
Re04.g10830 protein, putative 7085 17335 27585
Re04.g 10840 NTP binding protein, putative 7086 17336 27586
Re04.g 10850 GDP-mannose transporter 7087 17337 27587
Re04.g 10860 Uncharacterized protein 7088 17338 27588
Re04.g10870 Putative uncharacterized protein 7089 17339 27589
Pseudouridylate synthase family
Re04.g10880 protein 7090 17340 27590
Re04.g10890 Uncharacterized protein 7091 17341 27591 31774 33264
Re04.g10900 Putative uncharacterized protein 7092 17342 27592
Re04.g10910 Uncharacterized protein 7093 17343 27593 31775 33265
Eukaryotic peptide chain release
Re04.g 10920 factor subunit 1 7094 17344 27594
Re04.g10930 Uncharacterized protein 7095 17345 27595
25S rRNA adenine-N(l )
Re04.g 10940 methyltransferase EC=2.1.1.- 7096 17346 27596
Re04.g 10950 60S ribosomal protein L23 7097 17347 27597
Mitochondrial intermembrane
space translocase subunit Tim10,
Re04.g 10960 putative 7098 17348 27598
Cell cycle control protein
Re04.g10970 Cwf14/Bud31 , putative 7099 17349 27599
Re04.g10980 Forkhead box protein L2 7100 17350 27600
Re04.g10990 Aspartokinase 7101 17351 27601
Re04.g1 1000 Putative uncharacterized protein 7102 17352 27602
Hemoglobin and proliferation
Re04.g1 1010 regulated protein 7103 17353 27603
Inosine triphosphate
Re04.g 1 1020 pyrophosphatase EC=3.6.1.19 7104 17354 27604
Re04.g1 1030 Class V myosin (Myo4), putative 7105 17355 27605
Nucleosome assembly protein
Re04.g 1 1040 Nap1 , putative 7106 17356 27606
Re04.g 1 1050 P-type ATPase, putative 7107 17357 27607
Re04.g 1 1060 Putative uncharacterized protein 7108 17358 27608
Serine/threonine-protein kinase
Re04.g1 1070 bur-1 7109 17359 27609
D-3-phosphoglycerate
Re04.g1 1080 dehydrogenase 71 10 17360 27610
Re04.g1 1090 Seryl-tRNA synthetase 71 1 1 17361 2761 1
Rheb small monomeric GTPase
Re04.g1 1 100 RhbA 71 12 17362 27612
Re04.g1 1 1 10 Putative uncharacterized protein 71 13 17363 27613
Cytosine deaminase-uracil
phosphoribosyltransferase fusion
Re04.g1 1 120 protein 71 14 17364 27614
Transcription elongation factor,
Re04.g1 1 130 putative 71 15 17365 27615
Re04.g1 1 140 40S ribosomal protein S1 71 16 17366 27616
Mitochondrial import inner
Re04.g1 1 150 membrane translocase subunit 71 17 17367 27617 TIM 17, putative
Re04.g1 1 160 Putative uncharacterized protein 71 18 17368 27618
Re04.g1 1 170 Putative uncharacterized protein 71 19 17369 27619
Re04.g1 1 180 Retrovirus polyprotein, putative 7120 17370 27620
Re04.g1 1 190 Uncharacterized protein 7121 17371 27621
Re04.g1 1200 Putative uncharacterized protein 7122 17372 27622
Re04.g1 1210 Uncharacterized protein 7123 17373 27623
Re04.g 1 1220 Transposon, putative 7124 17374 27624
Re04.g1 1230 Uncharacterized protein 7125 17375 27625
Re04.g 1 1240 Uncharacterized protein 7126 17376 27626
Re04.g 1 1250 Putative uncharacterized protein 7127 17377 27627
Re04.g 1 1260 Putative uncharacterized protein 7128 17378 27628
Re04.g1 1270 Hexose carrier protein 7129 17379 27629
Re04.g1 1280 Uncharacterized protein 7130 17380 27630
Re04.g1 1290 Uncharacterized protein 7131 17381 27631
DNA-directed RNA polymerases
Re04.g1 1300 N/8 kDa subunit superfamily 7132 17382 27632
Re04.g1 1310 Uncharacterized protein 7133 17383 27633
Re04.g 1 1320 Uncharacterized protein 7134 17384 27634
D-lactate dehydrogenase
Re04.g1 1330 (Cytochrome) 7135 17385 27635
Re04.g 1 1340 Xylitol dehydrogenase 7136 17386 27636
Re04.g 1 1350 Ras family GTPase (Rab4b) 7137 17387 27637
Re04.g 1 1360 BZIP family transcription factor 7138 17388 27638
Re04.g1 1370 hypothetical protein 7139 17389 27639
Membrane bound cation
Re04.g1 1380 transporter, putative 7140 17390 27640
Re04.g1 1390 Putative uncharacterized protein 7141 17391 27641
Re04.g1 1400 Putative uncharacterized protein 7142 17392 27642
Polysaccharide synthase Cps1 ,
Re04.g1 1410 putative 7143 17393 27643 31776 33266
Re04.g 1 1420 F1 -ATP synthase assembly protein 7144 17394 27644 31777 33267
Oxysterol binding protein (Osh1 ),
Re04.g1 1430 putative 7145 17395 27645
Re04.g 1 1440 hypothetical protein 7146 17396 27646 31778 33268
Re04.g 1 1450 Predicted protein 7147 17397 27647 31779 33269
Re04.g 1 1460 Malic enzyme 7148 17398 27648
Alcohol dehydrogenase, zinc-
Re04.g1 1470 containing 7149 17399 27649
Re04.g1 1480 Putative uncharacterized protein 7150 17400 27650
SNF2 family helicase/ATPase
Re04.g1 1490 (Swr1 ), putative 7151 17401 27651
Re04.g 1 1500 Uncharacterized protein 7152 17402 27652
Re04.g1 1510 Putative uncharacterized protein 7153 17403 27653
L-PSP endoribonuclease family
Re04.g 1 1520 protein (Hm l ), putative 7154 17404 27654
Re04.g 1 1530 Uncharacterized protein 7155 17405 27655
Re04.g 1 1540 hypothetical protein 7156 17406 27656
Re04.g 1 1550 Adenine phosphoribosyltransferase 7157 17407 27657 1
Re04.g1 1560 Putative uncharacterized protein 7158 17408 27658 31780 33270
Re04.g1 1570 Putative uncharacterized protein 7159 17409 27659
U5 snRNP complex subunit,
Re04.g1 1580 putative 7160 17410 27660
Putative uncharacterized protein
Re04.g1 1590 An12g00380 7161 1741 1 27661
cAMP-dependent protein kinase
Re04.g1 1600 pathway protein (Som1 ), putative 7162 17412 27662
Re04.g1 1610 Putative uncharacterized protein 7163 17413 27663
Re04.g1 1620 Uncharacterized protein 7164 17414 27664
Re04.g1 1630 Uncharacterized protein 7165 17415 27665
Re04.g1 1640 hypothetical protein 7166 17416 27666
Re04.g1 1650 Uncharacterized protein 7167 17417 27667
Re04.g1 1660 Putative uncharacterized protein 7168 17418 27668
Ribosomal small subunit assembly
Re04.g1 1670 protein 7169 17419 27669
Re04.g1 1680 Pc16g05520 protein 7170 17420 27670
Re04.g1 1690 Uncharacterized protein 7171 17421 27671
Re04.g1 1700 Uncharacterized protein 7172 17422 27672
Re04.g1 1710 Reverse transcriptase, putative 7173 17423 27673
Re04.g1 1720 hypothetical protein 7174 17424 27674
Meiotic recombination protein
Re04.g1 1730 drnd 7175 17425 27675
Zinc knuckle domain-containing
Re04.g1 1740 protein 7176 17426 27676
UDP-N-acetylglucosamine
Re04.g1 1750 pyrophosphorylase 7177 17427 27677
Cyclophilin-type peptidyl-prolyl cis-
Re04.g1 1760 trans isomerase 7178 17428 27678
Streptococcal hemagglutinin
Re04.g1 1770 protein, putative 7179 17429 27679
Re04.g1 1780 hypothetical protein 7180 17430 27680
Re04.g1 1790 40S ribosomal protein S24 7181 17431 27681
Re04.g1 1800 Uncharacterized protein 7182 17432 27682
Re04.g1 1810 Putative uncharacterized protein 7183 17433 27683
Re04.g1 1820 Similar to An12g02310 7184 17434 27684
Ran-binding protein (RanBPM),
Re04.g1 1830 putative 7185 17435 27685
Re04.g1 1840 Uncharacterized protein 7186 17436 27686
Re04.g1 1850 Uncharacterized protein 7187 17437 27687
Membrane associated DnaJ
Re04.g1 1860 chaperone, putative 7188 17438 27688 31781 33271
RNA polymerase I subunit Rpa43,
Re04.g1 1870 putative 7189 17439 27689
Toxin biosynthesis protein (Tri7),
Re04.g1 1880 putative 7190 17440 27690 31782 33272
Re04.g1 1890 Uncharacterized protein 7191 17441 27691
Re04.g1 1900 Monodehydroascorbate/ferredoxin 7192 17442 27692 reductase
Re04.g1 1910 Gh61 isozyme a EC=3.2.1.4 7193 17443 27693 31783 33273
Re04.g 1 1920 hypothetical protein 7194 17444 27694
Re04.g1 1930 MFS transporter 7195 17445 27695
Re04.g 1 1940 Amino acid permease, putative 7196 17446 27696
Re04.g 1 1950 Uncharacterized protein 7197 17447 27697
Arrestin (Or S-antigen) domain
Re04.g 1 1960 protein 7198 17448 27698
Re04.g1 1970 Triacylglycerol lipase, putative 7199 17449 27699
Re04.g1 1980 Predicted protein 7200 17450 27700
Cytochrome c oxidase assembly
Re04.g1 1990 protein 7201 17451 27701 31784 33274
Indoleamine 2,3-dioxygenase
Re04.g12000 family protein 7202 17452 27702
Re04.g12010 F-box domain protein 7203 17453 27703
Re04.g 12020 Putative uncharacterized protein 7204 17454 27704
Re04.g12030 hypothetical protein 7205 17455 27705
Re04.g 12040 Uncharacterized protein 7206 17456 27706
Re04.g 12050 Pc21 g22150 protein Precursor 7207 17457 27707 31785 33275
Re04.g 12060 Putative uncharacterized protein 7208 17458 27708
Re04.g12070 Uncharacterized protein 7209 17459 27709
Re04.g12080 Uncharacterized protein 7210 17460 27710
Re04.g12090 Uncharacterized protein 721 1 17461 2771 1 31786 33276
Re04.g12100 C6 zinc finger domain protein 7212 17462 27712
Re04.g121 10 Uncharacterized protein 7213 17463 27713
Re04.g12120 Uncharacterized protein 7214 17464 27714
Re04.g12130 hypothetical protein 7215 17465 27715
Re04.g12140 Putative uncharacterized protein 7216 17466 27716
DNA-directed RNA polymerase
Re04.g12150 EC=2.7.7.6 7217 17467 27717
Re04.g12160 DUF1716 domain protein 7218 17468 27718
TOM core complex subunit Tom6,
Re04.g12170 putative 7219 17469 27719
Exosomal 3'-5' exoribonuclease
Re04.g12180 complex, subunit Rrp44/Dis3 7220 17470 27720
Re04.g12190 Uncharacterized protein 7221 17471 27721
Re04.g 12200 Putative uncharacterized protein 7222 17472 27722
Re04.g12210 Putative uncharacterized protein 7223 17473 27723
Molybdopterin synthase sulfur
Re04.g 12220 carrier subunit 7224 17474 27724
Re04.g 12230 Putative uncharacterized protein 7225 17475 27725
Re04.g 12240 Integral membrane protein 7226 17476 27726 31787 33277
Re04.g 12250 Uncharacterized protein 7227 17477 27727
Re04.g 12260 Putative uncharacterized protein 7228 17478 27728
Re04.g 12270 Uncharacterized protein 7229 17479 27729
Putative uncharacterized protein
Re04.g 12280 An04g04700 EC=2.1.1.6 7230 17480 27730
Re04.g 12290 hypothetical protein 7231 17481 27731
Re04.g12300 Uncharacterized protein 7232 17482 27732 Re04.g 12320 MFS transporter Fmp42, putative 7233 17483 27733
Re04.g12330 Putative uncharacterized protein 7234 17484 27734
Re04.g 12340 Acetamidase, putative 7235 17485 27735
U2 auxiliary factor small subunit,
Re04.g 12350 putative 7236 17486 27736
Re04.g 12360 Putative uncharacterized protein 7237 17487 27737
Re04.g12370 hypothetical protein 7238 17488 27738
E3 ubiquitin-protein ligase PIB1 ,
Re04.g12380 putative 7239 17489 27739
C6 transcription factor (War1 ),
Re04.g12390 putative 7240 17490 27740
Alpha-glucosidase, putative
Re04.g 12400 EC=3.2.1.3 7241 17491 27741 31788 33278
Re04.g12410 Uncharacterized protein 7242 17492 27742
Re04.g 12420 Uncharacterized protein Fragment 7243 17493 27743
Re04.g 12430 C6 finger domain protein 7244 17494 27744
O-acetylhomoserine sulfhydrylase,
Re04.g 12440 putative EC=2.5.1.49 7245 17495 27745
Re04.g 12450 Putative uncharacterized protein 7246 17496 27746
Re04.g 12460 Aspartate kinase, putative 7247 17497 27747
Acetyl-CoA--deacetylcephalosporin
C acetyltransferase, putative
Re04.g 12470 EC=2.3.1.31 7248 17498 27748
Re04.g 12480 Nitrilase, putative 7249 17499 27749 31789 33279
Re04.g 12490 Uncharacterized protein 7250 17500 27750
Re04.g 12500 Plasma membrane iron permease 7251 17501 27751 31790 33280
Re04.g12510 Fet3 ferroxidase-like protein 7252 17502 27752 31791 33281
Re04.g 12520 Uncharacterized protein 7253 17503 27753
Re04.g 12530 C6 transcription factor, putative 7254 17504 27754
UTP-glucose-1-phosphate
Re04.g 12540 uridylyltransferase Ugp1 , putative 7255 17505 27755
Re04.g 12550 hypothetical protein 7256 17506 27756
AMID-like mitochondrial
Re04.g 12560 oxidoreductase, putative 7257 17507 27757 31792 33282
Membrane bound C2 domain
Re04.g 12570 protein (Vp115), putative 7258 17508 27758
Re04.g 12580 Haloacid dehalogenase, type II 7259 17509 27759
Re04.g 12590 Uncharacterized protein 7260 17510 27760
MFS peptide transporter Ptr2,
Re04.g 12600 putative 7261 1751 1 27761
Re04.g12610 Putative uncharacterized protein 7262 17512 27762
Re04.g 12620 Cap binding protein 7263 17513 27763
Integral membrane protein,
Re04.g 12630 Mpv17/PMP22 family, putative 7264 17514 27764 31793 33283
Re04.g 12640 Ribosomal protein S5 7265 17515 27765
Re04.g 12650 hypothetical protein 7266 17516 27766
Re04.g 12660 Putative uncharacterized protein 7267 17517 27767
Re04.g 12670 Opsin, putative 7268 17518 27768
Re04.g 12680 Isoleucyl-tRNA synthetase 7269 17519 27769 Re04.g 12690 UPF0183 domain protein 7270 17520 27770
Kinesin family protein (BimC),
Re04.g12700 putative 7271 17521 27771
Re04.g12710 Uncharacterized protein 7272 17522 27772
Re04.g 12720 Uncharacterized protein 7273 17523 27773
Re04.g12730 Putative uncharacterized protein 7274 17524 27774
Re04.g 12740 RPEL repeat protein 7275 17525 27775
Re04.g 12750 hypothetical protein 7276 17526 27776
Transl in-associated factor TraX,
Re04.g 12760 putative 7277 17527 27777
Re04.g12770 Putative uncharacterized protein 7278 17528 27778 31794 33284
Re04.g12790 hypothetical protein 7279 17529 27779
Re04.g12800 Uncharacterized protein 7280 17530 27780
Re04.g12810 Uncharacterized protein 7281 17531 27781
Re04.g 12820 Putative uncharacterized protein 7282 17532 27782
Re04.g12830 Squalene synthase 7283 17533 27783
Re04.g 12840 DnaJ domain protein 7284 17534 27784
Re04.g 12850 Putative uncharacterized protein 7285 17535 27785
Re04.g 12860 Putative uncharacterized protein 7286 17536 27786
DNA damage response protein
Re04.g12870 RcaA 7287 17537 27787
Re04.g12880 Uncharacterized protein 7288 17538 27788
Re04.g12890 GPI mannosyltransferase 1 7289 17539 27789 31795 33285
Re04.g12900 Salicylate hydroxylase 7290 17540 27790 31796 33286
Heat shock protein Hsp30/Hsp42,
Re04.g12910 putative 7291 17541 27791
Re04.g12930 Putative uncharacterized protein 7292 17542 27792
Re04.g 12940 hypothetical protein 7293 17543 27793
Re04.g 12950 hypothetical protein 7294 17544 27794
Re04.g 12960 Uncharacterized protein 7295 17545 27795
Glycoside hydrolase family 79
Re04.g12970 protein 7296 17546 27796 31797 33287
Re04.g12980 Uncharacterized protein 7297 17547 27797
Re04.g12990 Uncharacterized protein 7298 17548 27798
Re04.g13000 Uncharacterized protein 7299 17549 27799
MFS monocarboxylate transporter,
Re04.g13010 putative 7300 17550 27800
Re04.g 13020 Putative uncharacterized protein 7301 17551 27801
Molybdopterin cofactor sulfurase,
Re04.g13030 putative 7302 17552 27802
Re04.g 13040 hypothetical protein 7303 17553 27803
Cytochrome P450 oxidoreductase
Re04.g 13050 OrdA-like, putative 7304 17554 27804 31798 33288
Re04.g 13060 Guanine deaminase, putative 7305 17555 27805
Re04.g13070 Uncharacterized protein 7306 17556 27806
Re04.g13080 hypothetical protein 7307 17557 27807
Re05.g00010 Uncharacterized protein 7308 17558 27808
Re05.g00020 D-hydantoinase 7309 17559 27809
Re05.g00030 Putative dehydrogenase reductase 7310 17560 27810 protein
Fungal specific transcription factor
Re05.g00040 domain-containing protein 731 1 17561 2781 1
Re05.g00050 DEHA2F00396p 7312 17562 27812 31799 33289
Re05.g00060 Putative uncharacterized protein 7313 17563 27813
Re05.g00070 Allantoate permease, putative 7314 17564 27814
Re05.g00080 Uncharacterized protein 7315 17565 27815
Re05.g00090 G protein-coupled receptor GprD 7316 17566 27816
Re05.g00100 hypothetical protein 7317 17567 27817
Re05.g001 10 hypothetical protein 7318 17568 27818
Re05.g00120 Uncharacterized protein 7319 17569 27819
Re05.g00130 Putative uncharacterized protein 7320 17570 27820
Re05.g00140 Uncharacterized protein 7321 17571 27821
Oxidoreductase, 20G-Fe(ll)
Re05.g00150 oxygenase family, putative 7322 17572 27822
Re05.g00160 Uncharacterized protein 7323 17573 27823 31800 33290
O-acetylhomoserine (Thiol)-lyase,
Re05.g00170 putative EC=2.5.1.49 7324 17574 27824
Re05.g00180 CatA, catalase 7325 17575 27825
Re05.g00190 hypothetical protein 7326 17576 27826
Re05.g00200 Putative uncharacterized protein 7327 17577 27827 31801 33291
Re05.g00210 hypothetical protein 7328 17578 27828 31802 33292
Re05.g00220 LipA and NB-ARC domain protein 7329 17579 27829
Re05.g00230 Putative uncharacterized protein 7330 17580 27830
Re05.g00240 Uncharacterized protein 7331 17581 27831
Re05.g00250 Putative uncharacterized protein 7332 17582 27832 31803 33293
Re05.g00260 hypothetical protein 7333 17583 27833
Re05.g00270 Putative uncharacterized protein 7334 17584 27834
Re05.g00280 DEHA2F16412p 7335 17585 27835
Re05.g00290 Uncharacterized protein 7336 17586 27836 31804 33294
Re05.g00300 Uncharacterized protein 7337 17587 27837 31805 33295
Re05.g00310 hypothetical protein 7338 17588 27838
Re05.g00320 hypothetical protein 7339 17589 27839
Re05.g00330 Predicted protein 7340 17590 27840
Re05.g00340 Putative uncharacterized protein 7341 17591 27841
Re05.g00350 Amine oxidase 7342 17592 27842
Nuclear condensin complex
Re05.g00370 subunit Smc4, putative 7343 17593 27843
Re05.g00380 Uncharacterized protein 7344 17594 27844
Re05.g00390 CCCH zinc finger domain protein 7345 17595 27845
40S ribosomal protein S20,
Re05.g00400 putative 7346 17596 27846 31806 33296
Re05.g00410 CUE domain protein 7347 17597 27847
Delta 6-fatty acid desaturase/delta-
Re05.g00420 8 sphingolipid desaturase 7348 17598 27848
Re05.g00430 Phosphoglucomutase, putative 7349 17599 27849
Re05.g00440 Dihydrolipoamide dehydrogenase 7350 17600 27850
MFS monosaccharide transporter,
Re05.g00450 putative 7351 17601 27851 Re05.g00460 Putative uncharacterized protein 7352 17602 27852
Re05.g00470 hypothetical protein 7353 17603 27853
Re05.g00480 Uncharacterized protein 7354 17604 27854
CCR4-NOT transcription complex,
Re05.g00490 subunit 3 7355 17605 27855
D-tyrosyl-tRNA(Tyr) deacylase
Re05.g00500 EC=3.1.-.- 7356 17606 27856 31807 33297
Peptidyl-prolyl cis-trans isomerase
Re05.g00510 Cpr7, putative 7357 17607 27857
Re05.g00520 Formamidase FmdS 7358 17608 27858
Re05.g00530 Transmembrane protein UsgS 7359 17609 27859
Re05.g00540 Uncharacterized protein 7360 17610 27860
Re05.g00550 Pc20g04850 protein 7361 1761 1 27861
Re05.g00560 Nuclear protein (Sgd1 ), putative 7362 17612 27862
Re05.g00570 Putative uncharacterized protein 7363 17613 27863
Re05.g00580 Putative uncharacterized protein 7364 17614 27864 31808 33298
Re05.g00590 Putative uncharacterized protein 7365 17615 27865
Re05.g00600 Mfs sp sugar h+ symporter 7366 17616 27866
Re05.g00610 NADH dehydrogenase 7367 17617 27867
Re05.g00620 Uncharacterized protein 7368 17618 27868
Re05.g00630 Uncharacterized protein 7369 17619 27869
Re05.g00640 Uncharacterized protein 7370 17620 27870
Ubiquinone biosynthesis protein
Re05.g00650 Coq7, putative 7371 17621 27871
60S ribosomal protein L27a,
Re05.g00660 putative 7372 17622 27872
Re05.g00670 Pc20g05050 protein 7373 17623 27873 31809 33299
Re05.g00680 hypothetical protein 7374 17624 27874
Re05.g00690 hypothetical protein 7375 17625 27875
Catalytic activity: chsl of A.
nidulans catalyzes the alpha- 1
Re05.g00700 EC=2.4.1.16 7376 17626 27876
Integral membrane protein
Re05.g00710 (AFU.orthologue AFUA_2G01860) 7377 17627 27877
Re05.g00720 hypothetical protein 7378 17628 27878
Re05.g00730 Putative uncharacterized protein 7379 17629 27879
Re05.g00740 Sulfate transporter, putative 7380 17630 27880
Re05.g00750 Putative uncharacterized protein 7381 17631 27881
Cutinase transcription factor 1
Re05.g00760 alpha, putative 7382 17632 27882
Phytanoyl-CoA dioxygenase family
Re05.g00770 protein 7383 17633 27883
Small nucleolar ribonucleoprotein
Re05.g00780 complex subunit Utp15, putative 7384 17634 27884
Re05.g00790 Uncharacterized protein 7385 17635 27885
Re05.g00800 Uncharacterized protein 7386 17636 27886
Conserved serine proline-rich
Re05.g00810 protein 7387 17637 27887
Re05.g00820 Putative uncharacterized protein 7388 17638 27888 Re05.g00830 Uncharacterized protein 7389 17639 27889
Re05.g00840 Pre-mRNA splicing factor 7390 17640 27890
Re05.g00850 hypothetical protein 7391 17641 27891
Re05.g00860 Uncharacterized protein 7392 17642 27892
Re05.g00870 hypothetical protein 7393 17643 27893
Phosphoglycerate mutase family
Re05.g00880 protein 7394 17644 27894
Re05.g00890 Putative uncharacterized protein 7395 17645 27895
Non-classical export protein
Re05.g00900 Nce102, putative 7396 17646 27896 31810 33300
Re05.g00910 Aryl-alcohol dehydrogenase 7397 17647 27897
Re05.g00920 C6 transcription factor, putative 7398 17648 27898
Re05.g00930 Sucrase/ferredoxin domain protein 7399 17649 27899
Re05.g00940 hypothetical protein 7400 17650 27900 3181 1 33301
Re05.g00950 MFS transporter, putative 7401 17651 27901
Re05.g00960 Acid sphingomyelinase, putative 7402 17652 27902 31812 33302
Arabinan endo-1 ,5-alpha-L-
Re05.g00970 arabinosidase EC=3.2.1.99 7403 17653 27903 31813 33303
Short chain
dehydrogenase/reductase family
Re05.g00980 oxidoreductase, putative 7404 17654 27904
Probable alpha-fucosidase A
Re05.g00990 EC=3.2.1.51 Precursor 7405 17655 27905 31814 33304
Re05.g01000 Predicted protein 7406 17656 27906
Re05.g01010 Putative uncharacterized protein 7407 17657 27907
Re05.g01020 Putative uncharacterized protein 7408 17658 27908
DUF1264 domain-containing
Re05.g01030 protein 7409 17659 27909
Re05.g01040 Pc13g07060 protein 7410 17660 27910
Re05.g01050 Putative uncharacterized protein 741 1 17661 2791 1
Re05.g01060 hypothetical protein 7412 17662 27912
Re05.g01070 hypothetical protein 7413 17663 27913
Re05.g01080 RING finger domain protein 7414 17664 27914
Re05.g01090 Putative uncharacterized protein 7415 17665 27915
Re05.g01 100 Zn2Cys6 transcription factor 7416 17666 27916
Major facilitator superfamily
Re05.g01 1 10 transporter 7417 17667 27917
Re05.g01 120 Phosphoglycerate mutase, putative 7418 17668 27918
Re05.g01 130 hypothetical protein 7419 17669 27919
Re05.g01 140 hypothetical protein 7420 17670 27920
Re05.g01 150 Putative uncharacterized protein 7421 17671 27921
Re05.g01 160 Catechol dioxygenase 7422 17672 27922
Re05.g01 170 Regulatory protein SUAPRGA1 7423 17673 27923 31815 33305
Translation machinery-associated
Re05.g01 180 protein, putative 7424 17674 27924
Re05.g01 190 Exonuclease 7425 17675 27925
Re05.g01200 Putative uncharacterized protein 7426 17676 27926 31816 33306
Re05.g01210 Amino acid transporter, putative 7427 17677 27927
Re05.g01220 hypothetical protein 7428 17678 27928 Re05.g01230 Putative uncharacterized protein 7429 17679 27929 31817 33307
Re05.g01240 DNA primase EC=2.7.7.- 7430 17680 27930
Re05.g01250 hypothetical protein 7431 17681 27931
Re05.g01260 hypothetical protein 7432 17682 27932 31818 33308
Re05.g01270 Putative uncharacterized protein 7433 17683 27933
Sexual development protein
Re05.g01280 (LsdA), putative 7434 17684 27934 31819 33309
Re05.g01290 Threonine synthase 7435 17685 27935
Zinc-binding alcohol
dehydrogenase, putative
Re05.g01300 (AFlLorthologue AFUA_8G02430) 7436 17686 27936
Re05.g01310 hypothetical protein 7437 17687 27937
Re05.g01320 Bcs1 AAA-type ATPase, putative 7438 17688 27938
Re05.g01330 Uncharacterized protein 7439 17689 27939
Re05.g01340 Putative uncharacterized protein 7440 17690 27940
Re05.g01350 Coatomer subunit alpha, putative 7441 17691 27941
Re05.g01360 Sulfhydryl oxidase EC=1.8.3.2 7442 17692 27942
Re05.g01370 Transcriptional regulator, putative 7443 17693 27943
Putative uncharacterized protein
Re05.g01380 An16g02490 7444 17694 27944
Tubulin-specific chaperone c,
Re05.g01390 putative 7445 17695 27945
Tripeptidyl peptidase SED3
Re05.g01400 Fragment 7446 17696 27946
Proteasome regulatory particle
Re05.g01410 subunit (RpnL), putative 7447 17697 27947
Re05.g01420 Uncharacterized protein 7448 17698 27948
Re05.g01430 Predicted protein 7449 17699 27949
Re05.g01440 Putative uncharacterized protein 7450 17700 27950
Re05.g01450 Putative uncharacterized protein 7451 17701 27951
Translation repressor/antiviral
Re05.g01460 protein Ski3, putative 7452 17702 27952
Re05.g01470 Glycosyl hydrolase 7453 17703 27953
Re05.g01480 C6 transcription factor, putative 7454 17704 27954
Re05.g01490 Uncharacterized protein 7455 17705 27955
NADH-ubiquinone oxidoreductase
Re05.g01500 subunit GRIM-19 7456 17706 27956
tRNA m(1 )G methyltransferase
Re05.g01510 domain containing protein 7457 17707 27957
Vacuolar import and degradation
Re05.g01520 protein 7458 17708 27958
Re05.g01530 Uncharacterized protein 7459 17709 27959
Endosome-associated ubiquitin
Re05.g01540 isopeptidase (AmsH), putative 7460 17710 27960
Re05.g01550 Uncharacterized protein 7461 1771 1 27961 31820 33310
Re05.g01560 Predicted protein 7462 17712 27962
Re05.g01570 hypothetical protein 7463 17713 27963
Re05.g01580 Uncharacterized protein Fragment 7464 17714 27964
Re05.g01590 Predicted protein 7465 17715 27965 Re05.g01600 Uncharacterized protein 7466 17716 27966
Re05.g01610 Predicted protein Fragment 7467 17717 27967
Re05.g01620 Uncharacterized protein Fragment 7468 17718 27968
Isocitrate dehydrogenase [NADP]
Re05.g01630 EC=1.1.1.42 7469 17719 27969 31821 3331 1
Re05.g01640 C1 tetrahydrofolate synthase 7470 17720 27970
Re05.g01650 NRPS-like enzyme, putative 7471 17721 27971
Putative uncharacterized protein
Re05.g01660 An09g02320 7472 17722 27972
Re05.g01670 Putative uncharacterized protein 7473 17723 27973
Function: Tto1 can transpose
autonomously through reverse
transcription EC=2.7.7.49
EC=2.7.7.49 EC=2.7.7.49
Re05.g01680 EC=2.7.7.49 7474 17724 27974
Eukaryotic translation initiation
Re05.g01690 factor 3 subunit I 7475 17725 27975
Re05.g01700 Multiprotein-bridging factor 1 7476 17726 27976
Re05.g01710 hypothetical protein 7477 17727 27977
Re05.g01720 SH3 domain protein 7478 17728 27978
Re05.g01730 Putative uncharacterized protein 7479 17729 27979
Re05.g01740 Translational initiation factor 2 beta 7480 17730 27980
Re05.g01750 Uncharacterized protein 7481 17731 27981
Re05.g01760 hypothetical protein 7482 17732 27982
Re05.g01770 hypothetical protein 7483 17733 27983
Re05.g01780 Putative uncharacterized protein 7484 17734 27984
Re05.g01790 hypothetical protein 7485 17735 27985 31822 33312
Re05.g01800 hypothetical protein 7486 17736 27986
Glycine-rich RNA-binding protein,
Re05.g01810 putative 7487 17737 27987
Cation transport protein ChaC,
Re05.g01820 putative 7488 17738 27988
Re05.g01830 Putative uncharacterized protein 7489 17739 27989
Short-chain
dehydrogenase/reductase family
Re05.g01840 protein, putative 7490 17740 27990
Calcium binding modulator protein
Re05.g01850 (Alg2), putative 7491 17741 27991
Re05.g01860 MFS drug transporter, putative 7492 17742 27992
Re05.g01870 SRF-type transcription factor RImA 7493 17743 27993
Morphogenesis protein (Msb1 ),
Re05.g01880 putative 7494 17744 27994
Re05.g01890 Putative uncharacterized protein 7495 17745 27995
Cystathionine beta-synthase (Beta-
Re05.g01900 thionase), putative 7496 17746 27996
Mitochondrial phosphate carrier
Re05.g01910 protein 7497 17747 27997
Re05.g01920 Putative uncharacterized protein 7498 17748 27998
Re05.g01930 Putative uncharacterized protein 7499 17749 27999 Acetyltransferase, GNAT family
Re05.g01940 family 7500 17750 28000
Re05.g01950 60S ribosomal protein L33 7501 17751 28001
Glucose-6-phosphate 1 -
Re05.g01960 dehydrogenase EC=1.1.1.49 7502 17752 28002
Re05.g01970 Sucrose transport protein, putative 7503 17753 28003
Re05.g01980 Putative uncharacterized protein 7504 17754 28004 31823 33313
Re05.g01990 Putative uncharacterized protein 7505 17755 28005
Re05.g02000 hypothetical protein 7506 17756 28006
Re05.g02010 ThiJ/Pfpl family protein 7507 17757 28007
SNF2 family helicase/ATPase,
Re05.g02020 putative 7508 17758 28008
tRNA dihydrouridine synthase
Re05.g02030 (Smm1 ), putative 7509 17759 28009
Re05.g02040 Inorganic diphosphatase, putative 7510 17760 28010 31824 33314
Re05.g02050 Putative uncharacterized protein 751 1 17761 2801 1
Re05.g02060 Uncharacterized protein 7512 17762 28012
Re05.g02070 Uncharacterized protein 7513 17763 28013
Re05.g02080 Putative uncharacterized protein 7514 17764 28014
Succinate dehydrogenase,
Re05.g02090 flavoprotein subunit 7515 17765 28015
Proteasome regulatory particle
Re05.g02100 subunit Rpt1 , putative 7516 17766 28016
Re05.g021 10 T-complex protein 1 subunit delta 7517 17767 28017
Re05.g02120 Mercuric reductase 7518 17768 28018
Pheromone maturation dipeptidyl
Re05.g02130 aminopeptidase DapB 7519 17769 28019
Transcriptional activator of ethanol
Re05.g02140 catabolism AlcS 7520 17770 28020
Remark: the A. niger ORF is N- terminally truncated due to the
Re05.g02150 contig border Fragment 7521 17771 28021
Glycosyl transferase, group 1
Re05.g02160 family protein 7522 17772 28022 31825 33315
Endo alpha-1 ,4
Re05.g02180 polygalactosaminidase, putative 7523 17773 28023
Re05.g02190 hypothetical protein 7524 17774 28024
Re05.g02200 Uncharacterized protein 7525 17775 28025
UDP-glucose 4-epimerase
Re05.g02210 EC=5.1.3.2 7526 17776 28026
Re05.g02220 Putative uncharacterized protein 7527 17777 28027
Re05.g02230 hypothetical protein 7528 17778 28028
Re05.g02240 Pc20g06220 protein 7529 17779 28029
Alpha-ketoglutarate-dependent
Re05.g02250 taurine dioxygenase 7530 17780 28030
Re05.g02260 Transporter 7531 17781 28031
Re05.g02270 Putative uncharacterized protein 7532 17782 28032
Phosphoinositide-specific
Re05.g02280 phospholipase C, putative 7533 17783 28033 Re05.g02290 Uncharacterized protein 7534 17784 28034
Re05.g02300 Uncharacterized protein 7535 17785 28035
Re05.g02310 GABA permease GabA 7536 17786 28036
Peroxisome biosynthesis protein
Re05.g02320 (PAS8/Peroxin-6), putative 7537 17787 28037
Re05.g02330 Cytochrome P450 monooxygenase 7538 17788 28038
Re05.g02340 Putative uncharacterized protein 7539 17789 28039
Similarity corresonds only to the N-
Re05.g02350 terminal region 7540 17790 28040
Re05.g02360 PX domain protein 7541 17791 28041
Re05.g02370 Uncharacterized protein 7542 17792 28042
Re05.g02380 hypothetical protein 7543 17793 28043
Amino acid permease family
Re05.g02390 protein, putative 7544 17794 28044 31826 33316
Re05.g02410 hypothetical protein 7545 17795 28045
Re05.g02420 Putative uncharacterized protein 7546 17796 28046
tRNA (guanine(37)-N1)-
Re05.g02430 methyltransferase EC=2.1.1.228 7547 17797 28047
Polymerase (RNA) II (DNA
Re05.g02440 directed) polypeptide D 7548 17798 28048
Re05.g02450 Protein kinase, putative 7549 17799 28049
C6 transcription factor (OTam),
Re05.g02460 putative 7550 17800 28050
Re05.g02470 Uncharacterized protein 7551 17801 28051
Re05.g02480 Uncharacterized protein 7552 17802 28052
Re05.g02490 Uncharacterized protein 7553 17803 28053
Re05.g02500 Aspartyl aminopeptidase 7554 17804 28054
Re05.g02510 Uncharacterized protein 7555 17805 28055
Pyruvate dehydrogenase complex
Re05.g02520 component Pdx1 , putative 7556 17806 28056
Re05.g02530 Uncharacterized protein 7557 17807 28057
Structural maintenance of
Re05.g02540 chromosomes protein 7558 17808 28058
Re05.g02550 Uncharacterized protein 7559 17809 28059
Re05.g02560 hypothetical protein 7560 17810 28060 31827 33317
Re05.g02570 hypothetical protein 7561 1781 1 28061
Re05.g02580 Uncharacterized protein 7562 17812 28062
Re05.g02590 Uncharacterized protein 7563 17813 28063
Re05.g02600 Putative uncharacterized protein 7564 17814 28064
Re05.g02610 Putative uncharacterized protein 7565 17815 28065
Re05.g02620 MRS7 family protein 7566 17816 28066
Re05.g02630 NUDIX domain protein 7567 17817 28067 31828 33318
Re05.g02640 Putative uncharacterized protein 7568 17818 28068
Re05.g02650 Alpha-mannosidase 7569 17819 28069
Re05.g02660 Putative uncharacterized protein 7570 17820 28070
F-box and JmjC domain protein,
Re05.g02670 putative 7571 17821 28071
Eukaryotic translation initiation
Re05.g02680 factor 4, putative 7572 17822 28072 Re05.g02690 Putative uncharacterized protein 7573 17823 28073
Fumarylacetoacetate hydrolase
Re05.g02700 family protein 7574 17824 28074
Re05.g02710 Checkpoint protein kinase, putative 7575 17825 28075
Re05.g02720 Cell wall protein, putative 7576 17826 28076 31829 33319
Re05.g02730 Putative uncharacterized protein 7577 17827 28077
Re05.g02740 Putative uncharacterized protein 7578 17828 28078
Re05.g02750 Putative uncharacterized protein 7579 17829 28079
Short-chain
dehydrogenase/oxidoreductase,
Re05.g02760 putative 7580 17830 28080 31830 33320
Re05.g02770 Putative uncharacterized protein 7581 17831 28081
Re05.g02780 Putative uncharacterized protein 7582 17832 28082
Re05.g02790 Putative uncharacterized protein 7583 17833 28083
Re05.g02810 Putative uncharacterized protein 7584 17834 28084
ATP-dependent Clp protease,
Re05.g02820 proteolytic subunit ClpP 7585 17835 28085
Re05.g02830 Uncharacterized protein 7586 17836 28086 31831 33321
Re05.g02840 Gamma-glutamyltranspeptidase 7587 17837 28087
Re05.g02850 Argininosuccinate lyase 7588 17838 28088
Re05.g02860 Uncharacterized protein 7589 17839 28089
Re05.g02870 Uncharacterized protein 7590 17840 28090
Re05.g02880 Putative uncharacterized protein 7591 17841 28091
Re05.g02890 Nucleolin protein Nsr1 , putative 7592 17842 28092
Re05.g02900 Glucosyltransferase 7593 17843 28093
Cytochrome c oxidase copper
Re05.g02910 chaperone Cox17, putative 7594 17844 28094 31832 33322
Re05.g02920 Ran GTPase activating protein 1 7595 17845 28095
Re05.g02930 Transcription elongation factor S-ll 7596 17846 28096
Re05.g02940 Uncharacterized protein 7597 17847 28097 31833 33323
Re05.g02950 Uncharacterized protein 7598 17848 28098
Re05.g02960 Uncharacterized protein 7599 17849 28099 31834 33324
Phenylalanine ammonia-lyase
Re05.g02970 EC=4.3.1.24 7600 17850 28100
Re05.g02980 Putative uncharacterized protein 7601 17851 28101
Re05.g02990 Endo xylanase, putative 7602 17852 28102 31835 33325
Lipid A export ATP-
Re05.g03000 binding/permease protein msbA 7603 17853 28103
Re05.g03010 Putative uncharacterized protein 7604 17854 28104
Re05.g03020 Solute carrier family 2 7605 17855 28105 31836 33326
Re05.g03030 Putative uncharacterized protein 7606 17856 28106
Re05.g03040 C6 transcription factor, putative 7607 17857 28107
Re05.g03050 5-oxoprolinase, putative 7608 17858 28108
Plasma membrane H+ATPase
Re05.g03060 Pma1 EC=3.6.3.6 7609 17859 28109
Re05.g03070 Putative pectin methylesterase 7610 17860 281 10 31837 33327
Re05.g03080 hypothetical protein 761 1 17861 281 1 1
Re05.g03090 Uncharacterized protein 7612 17862 281 12
Re05.g03100 Pc22g 17680 protein 7613 17863 281 13 Re05.g031 10 Pc22g 17670 protein 7614 17864 281 14
Re05.g03120 Putative uncharacterized protein 7615 17865 281 15
Re05.g03130 Pc22g 17630 protein 7616 17866 281 16
Re05.g03140 Putative uncharacterized protein 7617 17867 281 17
Re05.g03150 Predicted protein 7618 17868 281 18
Re05.g03160 Uncharacterized protein 7619 17869 281 19
Cytochrome P450, putative
Re05.g03170 (Eurofung) 7620 17870 28120 31838 33328
Metallo-beta-lactamase
Re05.g03180 superfamily protein 7621 17871 28121
Re05.g03190 ABC1 domain protein 7622 17872 28122
Re05.g03200 Putative uncharacterized protein 7623 17873 28123
Re05.g03210 Putative uncharacterized protein 7624 17874 28124
Re05.g03220 Predicted protein 7625 17875 28125
Re05.g03230 hypothetical protein 7626 17876 28126
Re05.g03240 Uncharacterized protein 7627 17877 28127
Re05.g03250 Putative uncharacterized protein 7628 17878 28128
Re05.g03260 Putative uncharacterized protein 7629 17879 28129
Re05.g03270 Putative uncharacterized protein 7630 17880 28130
Re05.g03280 Predicted protein 7631 17881 28131
Re05.g03290 Putative uncharacterized protein 7632 17882 28132
Re05.g03300 hypothetical protein 7633 17883 28133
MYB DNA-binding domain-
Re05.g03310 containing protein 7634 17884 28134
Re05.g03320 Putative uncharacterized protein 7635 17885 28135
Re05.g03330 Putative uncharacterized protein 7636 17886 28136
Re05.g03340 Pc17g00310 protein 7637 17887 28137
Re05.g03350 hypothetical protein 7638 17888 28138
Re05.g03360 Putative uncharacterized protein 7639 17889 28139
Re05.g03370 Uncharacterized protein 7640 17890 28140
Re05.g03380 Putative uncharacterized protein 7641 17891 28141
Re05.g03390 Predicted protein 7642 17892 28142
Re05.g03400 Uncharacterized protein 7643 17893 28143
Similar to short-chain
Re05.g03410 dehydrogenase/reductase SDR 7644 17894 28144 31839 33329
Re05.g03420 Predicted protein 7645 17895 28145
Re05.g03430 Putative uncharacterized protein 7646 17896 28146
ER-Golgi SNARE complex subunit
Re05.g03440 (Sed5), putative 7647 17897 28147
Re05.g03450 hypothetical protein 7648 17898 28148 31840 33330
Re05.g03460 Potassium channel, putative 7649 17899 28149
Re05.g03470 Uncharacterized protein 7650 17900 28150
pH-response regulator protein
Re05.g03480 pall/RIM9 7651 17901 28151 31841 33331
Ribose-phosphate
Re05.g03490 pyrophosphokinase 3 7652 17902 28152
Re05.g03500 hypothetical protein 7653 17903 28153
Exo-beta-1 ,3-glucanase, putative
Re05.g03510 EC=3.2.1.39 7654 17904 28154 31842 33332 Re05.g03520 Putative uncharacterized protein 7655 17905 28155
Re05.g03530 Putative uncharacterized protein 7656 17906 28156 31843 33333
Re05.g03540 Putative uncharacterized protein 7657 17907 28157
Re05.g03550 Uncharacterized protein 7658 17908 28158
Re05.g03560 hypothetical protein 7659 17909 28159 31844 33334
Putative fad dependent
Re05.g03570 oxidoreductase superfamily protein 7660 17910 28160
Re05.g03580 Putative uncharacterized protein 7661 1791 1 28161
Re05.g03590 Uncharacterized protein 7662 17912 28162
Re05.g03600 Multidrug resistance protein Fnx1 7663 17913 28163
Re05.g03610 Uncharacterized protein 7664 17914 28164
Re05.g03620 hypothetical protein 7665 17915 28165
Re05.g03630 Putative uncharacterized protein 7666 17916 28166 31845 33335
Re05.g03640 Uncharacterized protein 7667 17917 28167 31846 33336
Permease of the major facilitator
Re05.g03650 superfamily 7668 17918 28168
Re05.g03660 Uncharacterized protein 7669 17919 28169 31847 33337
Re05.g03670 Uncharacterized protein 7670 17920 28170
Re05.g03680 G-patch domain protein, putative 7671 17921 28171
Re05.g03690 Oligo-1 ,6-glucosidase 7672 17922 28172
Molybdopterin synthase catalytic
Re05.g03700 subunit 7673 17923 28173
Re05.g03710 Protein SC01 7674 17924 28174
Re05.g03720 Putative uncharacterized protein 7675 17925 28175
Re05.g03730 Putative uncharacterized protein 7676 17926 28176
Re05.g03740 Uncharacterized protein yael 7677 17927 28177
Re05.g03750 Putative uncharacterized protein 7678 17928 28178
Re05.g03760 Uncharacterized protein 7679 17929 28179
SD08430p (AFU orthologue
Re05.g03770 AFUA_3G07290) 7680 17930 28180
Re05.g03780 Putative uncharacterized protein 7681 17931 28181
Re05.g03790 Putative uncharacterized protein 7682 17932 28182
Multidomain presynaptic cytomatrix
Re05.g03800 related protein 7683 17933 28183
Re05.g03810 Putative uncharacterized protein 7684 17934 28184
Re05.g03820 Putative uncharacterized protein 7685 17935 28185 31848 33338
Re05.g03830 hypothetical protein 7686 17936 28186
Re05.g03840 Putative uncharacterized protein 7687 17937 28187
Re05.g03850 Putative uncharacterized protein 7688 17938 28188
Re05.g03860 Polysaccharide deacetylase 7689 17939 28189 31849 33339
DEAD/DEAH box RNA helicase,
Re05.g03870 putative 7690 17940 28190
Re05.g03880 Putative uncharacterized protein 7691 17941 28191
Catalytic activity: ATP +
pantothenate <=> ADP + D-4'-
Re05.g03890 phosphopantothenate EC=2.7.1.33 7692 17942 28192
Re05.g03900 Putative uncharacterized protein 7693 17943 28193
PhosphatidylinositohUDP-GlcNAc
Re05.g03910 transferase PIG-C 7694 17944 28194 Glycosyl hydrolase, family 18,
Re05.g03920 putative 7695 17945 28195 31850 33340
Re05.g03930 Glutamine synthetase bacteria 7696 17946 28196
Re05.g03940 Putative uncharacterized protein 7697 17947 28197
Re05.g03950 Brain chitinase and chia, putative 7698 17948 28198 31851 33341
Succinate-semialdehyde
Re05.g03960 dehydrogenase, putative 7699 17949 28199
Re05.g03970 Putative uncharacterized protein 7700 17950 28200 31852 33342
Re05.g03980 Putative uncharacterized protein 7701 17951 28201
Sensor histidine kinase/response
Re05.g03990 regulator, putative 7702 17952 28202
Re05.g04000 MFS transporter, putative 7703 17953 28203
Re05.g04010 hypothetical protein 7704 17954 28204 31853 33343
Re05.g04020 hypothetical protein 7705 17955 28205
Re05.g04030 Similar to An08g1 1200 7706 17956 28206
Re05.g04040 hypothetical protein 7707 17957 28207
Re05.g04050 hypothetical protein 7708 17958 28208
Re05.g04060 UPF0016 domain protein, putative 7709 17959 28209 31854 33344
Myb-like DNA-binding protein,
Re05.g04070 putative 7710 17960 28210
Re05.g04080 Putative uncharacterized protein 771 1 17961 2821 1
Re05.g04090 Predicted protein 7712 17962 28212 31855 33345
Re05.g04100 Vacuolar carboxypeptidase Cps1 7713 17963 28213 31856 33346
Re05.g041 10 Putative uncharacterized protein 7714 17964 28214
Re05.g04120 Predicted protein 7715 17965 28215
Re05.g04130 Alpha-L-fucosidase 2, putative 7716 17966 28216
Re05.g04140 Putative uncharacterized protein 7717 17967 28217 31857 33347
Re05.g04150 hypothetical protein 7718 17968 28218
Re05.g04160 Uncharacterized protein 7719 17969 28219
Re05.g04170 Uncharacterized protein 7720 17970 28220
Re05.g04180 Uncharacterized protein 7721 17971 28221
Re05.g04190 hypothetical protein 7722 17972 28222
Re05.g04200 Uncharacterized protein 7723 17973 28223
Re05.g04210 Putative uncharacterized protein 7724 17974 28224
Re05.g04220 Putative uncharacterized protein 7725 17975 28225
Re05.g04230 Predicted protein Fragment 7726 17976 28226
Re05.g04240 Putative uncharacterized protein 7727 17977 28227 31858 33348
Re05.g04250 Annexin ANXC4 7728 17978 28228
Re05.g04260 Uncharacterized protein 7729 17979 28229
Re05.g04270 Cell division protein Sep4a 7730 17980 28230
Re05.g04280 hypothetical protein 7731 17981 28231 31859 33349
Re05.g04300 Uncharacterized protein 7732 17982 28232
Re05.g04310 Uncharacterized protein 7733 17983 28233
Re05.g04320 Putative uncharacterized protein 7734 17984 28234
Re05.g04330 40S ribosomal protein S9 7735 17985 28235
Re05.g04340 60S ribosomal protein L21 7736 17986 28236
Mitochondrial carrier protein
Re05.g04350 (Rim2), putative 7737 17987 28237
Re05.g04360 Conserved fungal protein 7738 17988 28238 31860 33350 Re05.g04370 hypothetical protein 7739 17989 28239
Re05.g04380 hypothetical protein 7740 17990 28240
Re05.g04400 hypothetical protein 7741 17991 28241
Re05.g04410 Alpha/beta hydrolase fold protein 7742 17992 28242
Extracellular proline-serine rich
Re05.g04420 protein 7743 17993 28243
Re05.g04430 RRM domain protein 7744 17994 28244
Re05.g04440 Protein translocase, putative 7745 17995 28245
Re05.g04450 Putative uncharacterized protein 7746 17996 28246
Re05.g04460 hypothetical protein 7747 17997 28247
Re05.g04470 Putative uncharacterized protein 7748 17998 28248 31861 33351
Re05.g04480 Sorting nexin-3 7749 17999 28249
Re05.g04490 MYB DNA-binding domain protein 7750 18000 28250
Re05.g04500 Uncharacterized protein 7751 18001 28251 31862 33352
Re05.g04510 Uncharacterized protein 7752 18002 28252
40S ribosomal protein S4, putative
Re05.g04520 (AFU.orthologue AFUA_3G06840) 7753 18003 28253
Re05.g04530 Transposase 7754 18004 28254
Aspartate-semialdehyde
Re05.g04540 dehydrogenase 7755 18005 28255
Similar to Levodione reductase
Re05.g04550 acc. no. Q9LBG2 7756 18006 28256
Re05.g04560 Oxidoreductase, FAD-binding 7757 18007 28257
Re05.g04570 Putative uncharacterized protein 7758 18008 28258
RNA-directed RNA polymerase
Re05.g04580 (Sad-1 ), putative 7759 18009 28259 31863 33353
Re05.g04590 Uncharacterized protein 7760 18010 28260 31864 33354
Re05.g04600 Ribosomal protein L37 7761 1801 1 28261
Re05.g04610 Uncharacterized protein 7762 18012 28262
Re05.g04620 DNA polymerase EC=2.7.7.7 7763 18013 28263
Re05.g04630 MFS sugar transporter, putative 7764 18014 28264
C6 transcription factor (Gal4),
Re05.g04640 putative 7765 18015 28265
Re05.g04650 Putative uncharacterized protein 7766 18016 28266
Cytochrome c oxidase subunit 6A,
Re05.g04660 mitochondrial 7767 18017 28267
Re05.g04670 DNA lyase, putative 7768 18018 28268
Re05.g04680 hypothetical protein 7769 18019 28269
Re05.g04690 Uncharacterized protein 7770 18020 28270
Alpha mating-type protein MAT1 -1 -
Re05.g04700 1 7771 18021 28271
Cytoskeleton assembly control
Re05.g04710 protein Sla2, putative 7772 18022 28272
Re05.g04720 PH domain-containing protein 7773 18023 28273
Ankyrin repeat domain protein,
Re05.g04730 putative 7774 18024 28274
Ubiquitin thiolesterase (OtuB1 ),
Re05.g04740 putative 7775 18025 28275
Re05.g04750 COP9 signalosome subunit 2 7776 18026 28276 (CsnB), putative
Re05.g04760 Putative uncharacterized protein 7777 18027 28277
Re05.g04770 Rho GTPase Rho3 7778 18028 28278
Re05.g04780 Octanoyltransferase EC=2.3.1.181 7779 18029 28279
Pyridoxamine phosphate oxidase,
Re05.g04790 putative 7780 18030 28280
Re05.g04800 Uncharacterized protein 7781 18031 28281
Re05.g04810 hypothetical protein 7782 18032 28282
Re05.g04820 NIPSNAP family protein 7783 18033 28283 31865 33355
Re05.g04830 Aminoalcoholphosphotransferase 7784 18034 28284
Re05.g04840 40S ribosomal protein S27 7785 18035 28285
Re05.g04850 hypothetical protein 7786 18036 28286
Re05.g04860 Methyltransferase, putative 7787 18037 28287
Re05.g04870 Uncharacterized protein 7788 18038 28288
Proteasome regulatory particle
Re05.g04880 subunit (RpnE), putative 7789 18039 28289
Re05.g04890 Dihydrofolate reductase 7790 18040 28290
Re05.g04900 Uncharacterized protein 7791 18041 28291
Re05.g04910 Uroporphyrin III methyltransferase 7792 18042 28292
Re05.g04920 Putative uncharacterized protein 7793 18043 28293
Deoxyribose-phosphate aldolase,
Re05.g04930 putative 7794 18044 28294
Re05.g04940 Quinone oxidoreductase 7795 18045 28295
Re05.g04950 Putative uncharacterized protein 7796 18046 28296
Ribosomal assembly complex
Re05.g04960 component Ipi3, putative 7797 18047 28297 31866 33356
Re05.g04970 Putative uncharacterized protein 7798 18048 28298
Re05.g04980 Putative uncharacterized protein 7799 18049 28299
Lipoyl synthase, mitochondrial
Re05.g04990 EC=2.8.1.8 Precursor 7800 18050 28300
Re05.g05000 Phosphoserine phosphatase 7801 18051 28301
3'-phosphoadenosine-5'-
Re05.g05010 phosphosulfate reductase 7802 18052 28302
Sulfate adenylyltransferase
Re05.g05020 EC=2.7.7.4 7803 18053 28303
2-heptaprenyl-1 ,4-naphthoquinone
Re05.g05030 methyltransferase, putative 7804 18054 28304
Re05.g05040 Putative uncharacterized protein 7805 18055 28305
Re05.g05050 Putative uncharacterized protein 7806 18056 28306
Re05.g05060 Pc13g 12490 protein 7807 18057 28307
Re05.g05070 Putative uncharacterized protein 7808 18058 28308
Re05.g05080 hypothetical protein 7809 18059 28309
Re05.g05090 Putative uncharacterized protein 7810 18060 28310
Re05.g05100 hypothetical protein 781 1 18061 2831 1
Re05.g051 10 Similar to An1 1g09830 7812 18062 28312
Iron-sulfur cluster biosynthesis
Re05.g05120 protein Isd 1 1 , putative 7813 18063 28313
Re05.g05130 Pc20g07750 protein 7814 18064 28314
Re05.g05140 Histone-lysine N-methyltransferase 7815 18065 28315 31867 33357 (Ash1 ), putative
Re05.g05150 Palmitoyltransferase EC=2.3.1.225 7816 18066 28316
Re05.g05160 Uncharacterized protein 7817 18067 28317
Re05.g05170 Protein mannosyltransferase 1 7818 18068 28318
Re05.g05180 Pre-mRNA splicing factor, putative 7819 18069 28319
Re05.g05190 hypothetical protein 7820 18070 28320
GDP/GTP exchange factor Sec2p,
Re05.g05200 putative 7821 18071 28321
DsDNA-binding protein PDCD5,
Re05.g05210 putative 7822 18072 28322
Ubiquinone biosynthesis protein
Re05.g05220 coq4, mitochondrial Precursor 7823 18073 28323 31868 33358
Re05.g05230 Putative uncharacterized protein 7824 18074 28324
Re05.g05240 Putative uncharacterized protein 7825 18075 28325
Re05.g05250 2-dehydropantoate 2-reductase 7826 18076 28326
Exosome-associated protein,
Re05.g05260 putative 7827 18077 28327
Re05.g05270 Uncharacterized protein 7828 18078 28328
Re05.g05280 Uncharacterized protein 7829 18079 28329
COX1 assembly protein Shy1 ,
Re05.g05290 putative 7830 18080 28330
Re05.g05300 Putative uncharacterized protein 7831 18081 28331
Re05.g05310 Similar to An1 1g10000 7832 18082 28332
Re05.g05320 Putative uncharacterized protein 7833 18083 28333
Re05.g05330 L-lysine 2,3-aminomutase, putative 7834 18084 28334
Re05.g05340 RNA binding protein 7835 18085 28335
Re05.g05350 Rho GTPase Rac, putative 7836 18086 28336
Re05.g05360 Putative uncharacterized protein 7837 18087 28337
Oxidoreductase, short chain
Re05.g05370 dehydrogenase/reductase family 7838 18088 28338
Re05.g05380 hypothetical protein 7839 18089 28339
Re05.g05390 C6 transcription factor, putative 7840 18090 28340
Re05.g05400 hypothetical protein 7841 18091 28341
Re05.g05410 Putative uncharacterized protein 7842 18092 28342 31869 33359
Rho GTPase activator (Rgd1 ),
Re05.g05420 putative 7843 18093 28343
Re05.g05430 MFS amine transporter, putative 7844 18094 28344
RNA polymerase II mediator
Re05.g05440 complex component Srb8, putative 7845 18095 28345
Re05.g05450 Putative uncharacterized protein 7846 18096 28346
Putative translation initiation factor
Re05.g05460 protein 7847 18097 28347
Re05.g05470 Putative uncharacterized protein 7848 18098 28348
Re05.g05480 Putative uncharacterized protein 7849 18099 28349 31870 33360
Cytochrome P450 oxidoreductase,
Re05.g05490 putative 7850 18100 28350
Re05.g05500 Putative uncharacterized protein 7851 18101 28351
Putative extracellular serine-rich
Re05.g05510 protein 7852 18102 28352 31871 33361 Re05.g05520 Reverse transcriptase, putative 7853 18103 28353
Re05.g05530 Uncharacterized protein 7854 18104 28354
Re05.g05540 Predicted protein 7855 18105 28355 31872 33362
Complex I intermediate associated
Re05.g05550 protein (Cia30), putative 7856 18106 28356
Re05.g05560 Cystathionine gamma-synthase 7857 18107 28357
Re05.g05570 Predicted protein 7858 18108 28358
Re05.g05580 Putative uncharacterized protein 7859 18109 28359
Re05.g05600 Exo-polygalacturonase, putative 7860 181 10 28360 31873 33363
Re05.g05610 Monooxygenase 7861 181 1 1 28361 31874 33364
Re05.g05620 Uncharacterized protein 7862 181 12 28362
Re05.g05630 Uncharacterized protein 7863 181 13 28363 31875 33365
Re05.g05640 Uncharacterized protein 7864 181 14 28364
Re05.g05650 Uncharacterized protein Fragment 7865 181 15 28365 31876 33366
Re05.g05660 Non-ribosomal peptide synthetase 7866 181 16 28366
Re05.g05670 Predicted protein 7867 181 17 28367
Re05.g05680 Putative uncharacterized protein 7868 181 18 28368
Re05.g05690 Methionyl-tRNA synthetase 7869 181 19 28369 31877 33367
Re05.g05700 Uncharacterized protein 7870 18120 28370
Re05.g05710 hypothetical protein 7871 18121 28371 31878 33368
Re05.g05720 Putative uncharacterized protein 7872 18122 28372 31879 33369
Re05.g05730 hypothetical protein 7873 18123 28373 31880 33370
Re05.g05740 Putative uncharacterized protein 7874 18124 28374
Anaphase-promoting complex
Re05.g05750 subunit Apc5, putative 7875 18125 28375 31881 33371
Phosphoribosyl-aminoimidazole-
Re05.g05760 succinocarboxamide synthase 7876 18126 28376
Hexaprenyl pyrophosphate
Re05.g05770 synthetase Coq1 , putative 7877 18127 28377 31882 33372
Proteasome regulatory particle
Re05.g05780 subunit (RpnC), putative 7878 18128 28378
Re05.g05790 Putative uncharacterized protein 7879 18129 28379
Transcription initiation factor TFIID
Re05.g05800 subunit 12, putative 7880 18130 28380
Re05.g05810 Putative uncharacterized protein 7881 18131 28381
Multicopy suppressor of stt4
Re05.g05820 mutation 7882 18132 28382
Re05.g05830 Histone H1 7883 18133 28383
Re05.g05840 Flap endonuclease 1 EC=3.1 7884 18134 28384 31883 33373
Fungal specific transcription factor,
Re05.g05850 putative 7885 18135 28385
Re05.g05860 Uncharacterized protein 7886 18136 28386 31884 33374
Re05.g05870 Maltose phosphorylase, putative 7887 18137 28387 31885 33375
Re05.g05880 Uncharacterized protein 7888 18138 28388
Re05.g05890 Putative uncharacterized protein 7889 18139 28389
Re05.g05900 Iterative type I polyketide synthase 7890 18140 28390
Cytochrome B-245 heavy chain,
Re05.g05910 putative EC=1.6.3.1 7891 18141 28391
Re05.g05920 Glutaryl-CoA dehydrogenase, 7892 18142 28392 putative
Re05.g05930 Pc20g07930 protein 7893 18143 28393
Re05.g05940 Glyoxalase family protein 7894 18144 28394 31886 33376
RNA processing protein Emg1 ,
Re05.g05950 putative 7895 18145 28395
Sister chromatid cohesion
Re05.g05960 acetyltransferase Eco1 , putative 7896 18146 28396
Sister chromatid cohesion
Re05.g05970 acetyltransferase Eco1 7897 18147 28397
Re05.g05980 Uncharacterized protein 7898 18148 28398
Eukaryotic translation initiation
Re05.g05990 factor subunit elF2A, putative 7899 18149 28399
Re05.g06000 Putative uncharacterized protein 7900 18150 28400
20S cyclosome subunit
Re05.g06010 (APC1/BimE), putative 7901 18151 28401
Re05.g06020 Transcription factor Rba50 7902 18152 28402
Re05.g06030 Putative uncharacterized protein 7903 18153 28403
Re05.g06040 IFRD domain protein 7904 18154 28404
Probable beta-galactosidase E
Re05.g06050 EC=3.2.1.23 Precursor 7905 18155 28405 31887 33377
Re05.g06060 Anterior fat body protein, putative 7906 18156 28406
Re05.g06070 Putative allantoin transport protein 7907 18157 28407
Putative uncharacterized protein
Re05.g06080 An04g04860 7908 18158 28408 31888 33378
Re05.g06090 Uncharacterized protein 7909 18159 28409 31889 33379
Re05.g06100 Cutinase, putative 7910 18160 28410 31890 33380
Re05.g061 10 hypothetical protein 791 1 18161 2841 1
Re05.g06120 Uncharacterized protein 7912 18162 28412 31891 33381
Re05.g06130 Putative uncharacterized protein 7913 18163 28413
Krueppel c2h2-type zinc finger
Re05.g06140 protein, putative 7914 18164 28414
L-PSP endoribonuclease family
Re05.g06150 protein (Brt1 ), putative 7915 18165 28415
Re05.g06160 Lipase, putative 7916 18166 28416
Re05.g06170 hypothetical protein 7917 18167 28417
Re05.g06180 Putative uncharacterized protein 7918 18168 28418
Transcription elongation factor
Re05.g06190 SPT6, putative 7919 18169 28419
Oxysterol binding protein (Osh3),
Re05.g06200 putative 7920 18170 28420
Re05.g06210 Uncharacterized protein 7921 18171 28421 31892 33382
Re05.g06220 hypothetical protein 7922 18172 28422 31893 33383
Re05.g06230 Pc18g01840 protein 7923 18173 28423
Re05.g06240 hypothetical protein 7924 18174 28424 31894 33384
Re05.g06250 Uncharacterized protein 7925 18175 28425
Re05.g06260 Uncharacterized protein 7926 18176 28426 31895 33385
Re05.g06270 Uncharacterized protein 7927 18177 28427 31896 33386
Re05.g06280 Putative uncharacterized protein 7928 18178 28428
Re05.g06290 Predicted protein 7929 18179 28429 31897 33387 Re05.g06300 hypothetical protein 7930 18180 28430
Re05.g06310 Pc21 g09450 protein 7931 18181 28431
Re05.g06320 Uncharacterized protein 7932 18182 28432
Re05.g06330 Pc21 g09460 protein 7933 18183 28433
Re05.g06340 Uncharacterized protein 7934 18184 28434
Re05.g06350 Pc21 g09480 protein 7935 18185 28435
Re05.g06360 Putative uncharacterized protein 7936 18186 28436
Re05.g06370 Aldehyde dehydrogenase 7937 18187 28437
Re05.g06380 Putative uncharacterized protein 7938 18188 28438
GPR1/FUN34/YaaH-class plasma
Re05.g06390 membrane protein 7939 18189 28439
Re05.g06400 Putative uncharacterized protein 7940 18190 28440
Re05.g06410 Amino acid permease, putative 7941 18191 28441
Re05.g06420 Uncharacterized protein 7942 18192 28442
Re05.g06430 Uncharacterized protein 7943 18193 28443
Re05.g06440 Putative uncharacterized protein 7944 18194 28444
Re05.g06450 Putative uncharacterized protein 7945 18195 28445
Re05.g06460 Uncharacterized protein 7946 18196 28446
Glucose-methanol-choline
Re05.g06470 oxidoreductase 7947 18197 28447
Re05.g06480 Putative uncharacterized protein 7948 18198 28448
Re05.g06490 Uncharacterized protein 7949 18199 28449
Gag/polymerase/env polyprotein,
Re05.g06500 putative 7950 18200 28450
Re05.g06510 Putative uncharacterized protein 7951 18201 28451
Re05.g06520 Uncharacterized protein 7952 18202 28452
RNA binding protein Rnp24,
Re05.g06530 putative 7953 18203 28453
Re05.g06540 Uncharacterized protein 7954 18204 28454
Re05.g06550 Uncharacterized protein 7955 18205 28455
Re05.g06560 Uncharacterized protein 7956 18206 28456 31898 33388
Re05.g06570 Putative uncharacterized protein 7957 18207 28457
Re05.g06580 hypothetical protein 7958 18208 28458 31899 33389
Re05.g06590 Uncharacterized protein 7959 18209 28459
Re05.g06600 3-dehydroquinate dehydratase I 7960 18210 28460 31900 33390
Re05.g06610 ZZ type zinc finger domain protein 7961 1821 1 28461
Re05.g06620 Acid phosphatase 7962 18212 28462 31901 33391
Re05.g06630 Cation diffusion facilitator, putative 7963 18213 28463
Re05.g06640 Predicted protein 7964 18214 28464
Re05.g06650 Predicted protein 7965 18215 28465
Re05.g06660 Putative uncharacterized protein 7966 18216 28466
Re05.g06670 Putative uncharacterized protein 7967 18217 28467 31902 33392
Alpha.alpha-trehalose-phosphate
synthase subunit Tps2, putative
Re05.g06680 EC=2.4.1.15 7968 18218 28468
Re05.g06690 hypothetical protein 7969 18219 28469
Re05.g06700 hypothetical protein 7970 18220 28470
Re05.g06710 hypothetical protein 7971 18221 28471
Re05.g06720 hypothetical protein 7972 18222 28472 Re05.g06730 hypothetical protein 7973 18223 28473 31903 33393
Pterin-4-alpha-carbinolamine
Re05.g06740 dehydratase family protein 7974 18224 28474 31904 33394
C6 transcription factor (Fcr1 ),
Re05.g06750 putative 7975 18225 28475
Re05.g06760 Aldose 1 -epimerase, putative 7976 18226 28476
Nicotinate-nucleotide
Re05.g06770 pyrophosphorylase 7977 18227 28477
Anucleate primary sterigmata
Re05.g06780 (ApsB), putative 7978 18228 28478
Re05.g06790 Putative uncharacterized protein 7979 18229 28479
Re05.g06800 Sec7 domain protein 7980 18230 28480
Integral membrane protein,
Re05.g06810 putative 7981 18231 28481
Re05.g06820 Putative uncharacterized protein 7982 18232 28482
2-dehydropantoate 2-reductase
Re05.g06830 EC=1.1.1.169 7983 18233 28483 31905 33395
MFS monocarboxylate transporter,
Re05.g06840 putative 7984 18234 28484
RAS small monomeric GTPase,
Re05.g06850 putative 7985 18235 28485
Re05.g06860 hypothetical protein 7986 18236 28486
Re05.g06870 Phospholipase D1 (PLD1 ), putative 7987 18237 28487
Re05.g06880 Uncharacterized protein 7988 18238 28488
ATP-dependent RNA helicase
Re05.g06890 CHL1 7989 18239 28489
Chitin synthase activator (Chs3),
Re05.g06900 putative 7990 18240 28490
Re05.g06910 Pc20g08260 protein 7991 18241 28491
Remark: the S. pombe homolog
scp3 is related to spindle poison
Re05.g06920 sensitivity 7992 18242 28492
Re05.g06930 RSC complex subunit 7993 18243 28493
OTU-like cysteine protease,
Re05.g06940 putative 7994 18244 28494
Re05.g06950 Putative uncharacterized protein 7995 18245 28495
Re05.g06960 Condensin complex subunit 1 7996 18246 28496
Re05.g06970 Cell cycle protein kinase, putative 7997 18247 28497
Protein-L-isoaspartate 0-
Re05.g06980 methyltransferase EC=2.1.1.77 7998 18248 28498
Re05.g06990 DnaJ and TPR domain protein 7999 18249 28499 31906 33396
Putative uncharacterized protein
Re05.g07000 Fragment 8000 18250 28500
Re05.g07010 Mitochondrial citrate transporter 8001 18251 28501
ATP-dependent RNA helicase
Re05.g07020 DHH1 8002 18252 28502
Re05.g07030 DNA repair protein Rad18 8003 18253 28503
Glutamate carboxypeptidase,
Re05.g07040 putative 8004 18254 28504
Re05.g07050 60S ribosomal protein L20, putative 8005 18255 28505 31907 33397 Re05.g07060 Putative uncharacterized protein 8006 18256 28506
Cystathionine gamma-synthase,
Re05.g07070 putative 8007 18257 28507
Re05.g07080 Putative uncharacterized protein 8008 18258 28508
Nuclear envelope pore membrane
Re05.g07090 protein, putative 8009 18259 28509
Ubiquitin carboxyl-terminal
Re05.g07100 hydrolase, family 1 protein 8010 18260 28510
Re05.g071 10 Putative uncharacterized protein 801 1 18261 2851 1
Putative uncharacterized protein
Re05.g07120 An1 1 g11280 EC=2.3.1.61 8012 18262 28512
Re05.g07130 Histone H2A 8013 18263 28513
Re05.g07140 Histone H2B 8014 18264 28514
Autophagy cysteine endopeptidase
Re05.g07150 Atg4, putative 8015 18265 28515
Re05.g07160 Pc20g08620 protein 8016 18266 28516
Re05.g07170 J domain containing protein 8017 18267 28517
Re05.g07180 F-box domain protein 8018 18268 28518
Re05.g07190 Putative uncharacterized protein 8019 18269 28519
Re05.g07200 Putative uncharacterized protein 8020 18270 28520
Gag/polymerase/env polyprotein,
Re05.g07210 putative 8021 18271 28521
Re05.g07220 Putative uncharacterized protein 8022 18272 28522
Re05.g07230 Uncharacterized protein 8023 18273 28523
Re05.g07240 Putative uncharacterized protein 8024 18274 28524
Re05.g07250 Putative uncharacterized protein 8025 18275 28525
Re05.g07260 Putative uncharacterized protein 8026 18276 28526
Re05.g07270 Uncharacterized protein 8027 18277 28527 31908 33398
Re05.g07280 Tryptophan-tRNA ligase 8028 18278 28528
Purine nucleoside phosphorylase
Re05.g07290 EC=2.4.2.1 8029 18279 28529
Nucleolus protein required for cell
Re05.g07300 viability, putative 8030 18280 28530
CCAAT-binding factor complex
Re05.g07310 subunit HapE 8031 18281 28531 31909 33399
Exocyst complex component
Re05.g07320 Sec15 8032 18282 28532
Re05.g07330 hypothetical protein 8033 18283 28533
Re05.g07340 hypothetical protein 8034 18284 28534
Function: Tto1 can transpose
autonomously through reverse
transcription EC=2.7.7.49
EC=2.7.7.49 EC=2.7.7.49
Re05.g07350 EC=2.7.7.49 8035 18285 28535
Re05.g07360 Meiosis protein MEI2, putative 8036 18286 28536
Re05.g07370 Putative uncharacterized protein 8037 18287 28537
Re05.g07380 Pc13g01930 protein Precursor 8038 18288 28538
Similarity to YBL028c of S.
Re05.g07390 cerevisiae 8039 18289 28539 Re05.g07400 MIZ zinc finger protein 8040 18290 28540
Re05.g07410 BET3 family protein 8041 18291 28541
Malate dehydrogenase
Re05.g07420 EC=1.1.1.37 8042 18292 28542
Re05.g07430 60S ribosomal protein L28 8043 18293 28543
Re05.g07440 Splicing factor 3b subunit 4 8044 18294 28544
Re05.g07450 TOM complex component Tom7 8045 18295 28545
Mitochondrial folate carrier protein
Re05.g07460 Flx1 , putative 8046 18296 28546
C2H2 type zinc finger containing
Re05.g07470 protein 8047 18297 28547
Transcriptional repressor
Re05.g07480 TupA/RocA, putative 8048 18298 28548
Re05.g07490 Sterol delta 5,6-desaturase ERG3 8049 18299 28549
Re05.g07500 Uncharacterized protein 8050 18300 28550 31910 33400
Re05.g07510 Putative uncharacterized protein 8051 18301 28551
Re05.g07520 Putative uncharacterized protein 8052 18302 28552
Re05.g07530 Cap binding protein 8053 18303 28553
Re05.g07540 hypothetical protein 8054 18304 28554
Glycogen synthase kinase (Skp1 ),
Re05.g07550 putative 8055 18305 28555
Mitochondrial import receptor
Re05.g07560 subunit (Tom40), putative 8056 18306 28556
6-phosphofructo-2-kinase, putative
Re05.g07570 EC=3.1.3.46 8057 18307 28557
Re05.g07580 Ubiquitin-related modifier 1 8058 18308 28558
RNA polymerase II Elongator
Re05.g07590 subunit 8059 18309 28559
Re05.g07600 ABC transporter, putative 8060 18310 28560
Re05.g07610 Uncharacterized protein 8061 1831 1 28561
Re05.g07620 Protein rail 8062 18312 28562
Re05.g07630 Putative uncharacterized protein 8063 18313 28563
Re05.g07640 Uncharacterized protein 8064 18314 28564
Re05.g07650 Uncharacterized protein 8065 18315 28565
Re05.g07660 12-oxophytodienoate reductase 8066 18316 28566
Re05.g07670 Xanthine dehydrogenase 8067 18317 28567
Re05.g07680 FAD binding domain protein 8068 18318 28568
Re05.g07690 Acetamidase 8069 18319 28569
Dehydrogenase with different
Re05.g07700 specificitie 8070 18320 28570
Re05.g07710 Polysaccharide deacetylase 8071 18321 28571
Re05.g07720 Monooxygenase, putative 8072 18322 28572
Re05.g07730 Uncharacterized protein 8073 18323 28573
Re05.g07740 Mitochondrial GTPase 8074 18324 28574
Re05.g07750 Cytokinesis protein sepA Fragment 8075 18325 28575
Re05.g07760 Similar to An15g00400 8076 18326 28576
Re05.g07770 Bas1 , putative 8077 18327 28577
Re05.g07780 Homoaconitase LysF 8078 18328 28578
Re05.g07790 Uncharacterized protein 8079 18329 28579 Cytochrome c mitochondrial import
Re05.g07800 factor (Cyc2), putative 8080 18330 28580
Re05.g07810 Amino acid transporter 8081 18331 28581
Re05.g07820 Activator 1 37 kDa subunit 8082 18332 28582
Histidine acid phosphatase family
Re05.g07830 protein 8083 18333 28583 3191 1 33401
Re05.g07840 Ferric-chelate reductase, putative 8084 18334 28584 31912 33402
Re05.g07850 Formate dehydrogenase 8085 18335 28585
Re05.g07860 Putative uncharacterized protein 8086 18336 28586 31913 33403
Re05.g07870 Uncharacterized protein 8087 18337 28587 31914 33404
Re05.g07880 Leucyl-tRNA synthetase 8088 18338 28588 31915 33405
Sucrase/ferredoxin-like family
Re05.g07890 protein Fmi1 , putative 8089 18339 28589
Re05.g07900 Aspartic protease EC=3.4.23.24 8090 18340 28590 31916 33406
Putative UDP-GlcNAc: N-
Re05.g07910 acetylglucosaminyltransferase 8091 18341 28591
Re05.g07920 CaaX prenyl proteinase Reel 8092 18342 28592
Re05.g07930 hypothetical protein 8093 18343 28593
Re05.g07940 Serine-rich protein, putative 8094 18344 28594
Re05.g07950 Alpha/beta hydrolase fold protein 8095 18345 28595
Re05.g07960 MBOAT family protein, putative 8096 18346 28596
Putative uncharacterized protein
Re05.g07970 An15g00460 8097 18347 28597
Short chain
dehydrogenase/reductase family
Re05.g07980 protein 8098 18348 28598
Tyrosyl-DNA phosphodiesterase
Re05.g07990 domain protein 8099 18349 28599
Re05.g08000 ABC drug exporter AtrF 8100 18350 28600 31917 33407
Re05.g08010 hypothetical protein 8101 18351 28601
Camp independent regulatory
Re05.g08020 protein 8102 18352 28602
Re05.g08030 Uncharacterized protein 8103 18353 28603
Re05.g08040 hypothetical protein 8104 18354 28604
Re05.g08050 Putative uncharacterized protein 8105 18355 28605
Mitochondrial translation
optimization protein (Mto1 ),
Re05.g08060 putative 8106 18356 28606
1 ,2-dihydroxy-3-keto-5- methylthiopentene dioxygenase
Re05.g08070 EC=1.13.1 1.54 8107 18357 28607
Maintenance of mitochondrial
Re05.g08080 morphology protein 1 8108 18358 28608
Re05.g08090 Uncharacterized protein 8109 18359 28609 31918 33408
Transcription factor TFIIIB
Re05.g08100 component, putative 81 10 18360 28610
Histone ubiquitinationc protein
Re05.g081 10 (Bre1 ), putative 81 1 1 18361 2861 1
Re05.g08120 Putative uncharacterized protein 81 12 18362 28612
Re05.g08130 Molecular chaperone (ABC1 ), 81 13 18363 28613 putative
Putative uncharacterized protein
Re05.g08140 An15g00920 Precursor 81 14 18364 28614 31919 33409
Re05.g08150 Putative uncharacterized protein 81 15 18365 28615
Sn l kinase complex beta-subunit
Re05.g08160 Gal83, putative 81 16 18366 28616
tRNA N6-adenosine
th reo ny I ca rba moy I tra nsfe rase
Re05.g08170 EC=2.3.1.- 81 17 18367 28617
Re05.g08180 SET domain protein 81 18 18368 28618
Histone acetyltransferase complex
Re05.g08190 component Epl1 , putative 81 19 18369 28619
Re05.g08200 Calcineurin regulatory subunit CalA 8120 18370 28620
Re05.g08210 Putative uncharacterized protein 8121 18371 28621
Re05.g08220 37S ribosomal protein S9 8122 18372 28622 31920 33410
Elongation factor 1 gamma
Re05.g08230 domain-containing protein 8123 18373 28623
Re05.g08240 NIF domain protein 8124 18374 28624
Re05.g08250 rRNA biogenesis protein rrp36 8125 18375 28625
Re05.g08260 Putative uncharacterized protein 8126 18376 28626 31921 3341 1
Re05.g08270 hypothetical protein 8127 18377 28627 31922 33412
Re05.g08280 Chitin synthase G 8128 18378 28628
Putative uncharacterized protein
Re05.g08290 An09g04000 EC=6.3.2.19 8129 18379 28629
Cytochrome c oxidase subunit 7A
Re05.g08300 EC=1.9.3.1 8130 18380 28630 31923 33413
Bromodomain associated domain
Re05.g08310 protein 8131 18381 28631
Re05.g08320 Uncharacterized protein 8132 18382 28632
Re05.g08330 Uncharacterized protein 8133 18383 28633
Re05.g08340 Rad51 family DNA repair protein 8134 18384 28634
Pyridoxal-phosphate dependent
Re05.g08350 enzyme, putative 8135 18385 28635
Ketol-acid reductoisomerase
Re05.g08360 EC=1.1.1.86 8136 18386 28636 31924 33414
Isochorismatase family protein
Re05.g08370 family 8137 18387 28637
Enoyl-CoA hydratase/isomerase
Re05.g08380 family protein 8138 18388 28638
Heat shock protein Hsp30/Hsp42,
Re05.g08390 putative 8139 18389 28639
Re05.g08400 DNA repair protein Rex1 , putative 8140 18390 28640
Re05.g08410 Uncharacterized protein 8141 18391 28641
Serine/threonine protein kinase,
Re05.g08420 putative 8142 18392 28642
Re05.g08430 Uncharacterized protein 8143 18393 28643
Re05.g08440 Intradiol ring-cleavage dioxygenase 8144 18394 28644
Carboxy-cis.cis-muconate cyclase,
Re05.g08450 putative 8145 18395 28645
Re05.g08460 Alpha/beta hydrolase, putative 8146 18396 28646 Re05.g08470 Uncharacterized protein 8147 18397 28647
Re05.g08490 Adenylosuccinate lyase 8148 18398 28648
Re05.g08500 General substrate transporter 8149 18399 28649
Putative alpha-l-
Re05.g08510 arabinofuranosidase a protein 8150 18400 28650 31925 33415
Re05.g08520 Chromate ion transporter, putative 8151 18401 28651
Re05.g08530 hypothetical protein 8152 18402 28652
Re05.g08540 hypothetical protein 8153 18403 28653 31926 33416
Re05.g08550 Uncharacterized protein 8154 18404 28654
Re05.g08560 Glycolate oxidase 8155 18405 28655
Re05.g08570 Catalase B EC=1.1 1.1.6 Precursor 8156 18406 28656 31927 33417
Re05.g08590 Uncharacterized protein 8157 18407 28657
Re05.g08600 Reverse transcriptase, putative 8158 18408 28658
Re05.g08610 Uncharacterized protein 8159 18409 28659 31928 33418
Similar to Probable beta-
Re05.g08620 glucosidase A acc. no. Q2UUD6 8160 18410 28660 31929 33419
Re05.g08630 Uncharacterized protein 8161 1841 1 28661
Re05.g08640 Putative uncharacterized protein 8162 18412 28662 31930 33420
Re05.g08650 Uncharacterized protein 8163 18413 28663
Re05.g08660 Uncharacterized protein 8164 18414 28664
Re05.g08670 C6 transcription factor, putative 8165 18415 28665
Cytochrome P450 phenylacetate 2-
Re05.g08680 hydroxylase, putative 8166 18416 28666 31931 33421
Re05.g08690 Cytochrome P450, putative 8167 18417 28667
Re05.g08700 Putative uncharacterized protein 8168 18418 28668
Re05.g08710 Putative uncharacterized protein 8169 18419 28669
Re06.g00010 hypothetical protein 8170 18420 28670
Re06.g00020 Uncharacterized protein 8171 18421 28671 31932 33422
Re06.g00030 Beta-glucosidase 8172 18422 28672 31933 33423
Gag/polymerase/env polyprotein,
Re06.g00040 putative 8173 18423 28673
Re06.g00050 Uncharacterized protein 8174 18424 28674 31934 33424
Re06.g00060 Uncharacterized protein Fragment 8175 18425 28675
NAD(P)-binding Rossmann-fold
Re06.g00070 containing protein 8176 18426 28676
Re06.g00080 hypothetical protein 8177 18427 28677
Re06.g00090 Choline transport protein, putative 8178 18428 28678
Re06.g00100 Similar to O-methyltransferase 8179 18429 28679
Re06.g001 10 Hexose carrier protein 8180 18430 28680 31935 33425
Re06.g00120 Uncharacterized protein 8181 18431 28681
Re06.g00130 Uncharacterized protein 8182 18432 28682 31936 33426
Re06.g00140 Uncharacterized protein 8183 18433 28683 31937 33427
Re06.g00150 Putative uncharacterized protein 8184 18434 28684
Dimethylaniline monooxygenase,
Re06.g00160 putative 8185 18435 28685 31938 33428
Re06.g00170 Uncharacterized protein 8186 18436 28686
mRNA 3'-end-processing protein
Re06.g00180 YTH1 8187 18437 28687
Re06.g00190 Predicted protein 8188 18438 28688 Metallo-beta-lactamase
Re06.g00200 superfamily protein 8189 18439 28689
Re06.g00210 Predicted transporter 8190 18440 28690
Re06.g00220 Acyl-coenzyme A oxidase 8191 18441 28691
Re06.g00230 Uncharacterized protein 8192 18442 28692
Re06.g00240 Sugar transporter, putative 8193 18443 28693
Re06.g00250 Putative uncharacterized protein 8194 18444 28694 31939 33429
Re06.g00260 Predicted protein 8195 18445 28695
Re06.g00270 hypothetical protein 8196 18446 28696
Re06.g00280 Oligopeptide transporter, putative 8197 18447 28697
Re06.g00290 Putative uncharacterized protein 8198 18448 28698 31940 33430
Re06.g00300 Allantoate permease 8199 18449 28699
FAD-dependent pyridine
Re06.g00310 nucleotide-disulfide oxidoreductase 8200 18450 28700
Re06.g00320 Cytochrome P450 8201 18451 28701 31941 33431
Re06.g00330 Uncharacterized protein 8202 18452 28702
Re06.g00340 Putative uncharacterized protein 8203 18453 28703 31942 33432
Re06.g00350 DUF221 domain protein, putative 8204 18454 28704
Re06.g00360 GPI-GlcNAc transferase subunit P 8205 18455 28705
Cell differentiation and
Re06.g00370 development protein Fsr1/Pro1 1 8206 18456 28706
Re06.g00380 DNA repair protein rad14 8207 18457 28707
Re06.g00390 Putative uncharacterized protein 8208 18458 28708
tRNA and rRNA cytosine-C5-
Re06.g00400 methylase 8209 18459 28709
Acyl-CoA dehydrogenase family
Re06.g00410 protein 8210 18460 28710
Re06.g00420 hypothetical protein 821 1 18461 2871 1
Re06.g00430 Putative uncharacterized protein 8212 18462 28712
Glycoside hydrolase family 27
Re06.g00440 protein 8213 18463 28713 31943 33433
Re06.g00450 Uncharacterized protein 8214 18464 28714
Re06.g00460 hypothetical protein 8215 18465 28715
MATH and UCH domain protein,
Re06.g00470 putative 8216 18466 28716
Re06.g00480 Uncharacterized protein 8217 18467 28717
Peptidyl-prolyl cis-trans isomerase,
Re06.g00490 putative 8218 18468 28718
Re06.g00500 Uncharacterized protein 8219 18469 28719
Re06.g00510 Uncharacterized protein 8220 18470 28720 31944 33434
Re06.g00520 Putative uncharacterized protein 8221 18471 28721 31945 33435
Re06.g00530 Uncharacterized protein 8222 18472 28722
ARP2/3 complex subunit Ard 8,
Re06.g00540 putative Fragment 8223 18473 28723
Eukaryotic translation initiation
Re06.g00550 factor 3, gamma subunit, putative 8224 18474 28724
Re06.g00560 DUF455 domain protein 8225 18475 28725
Re06.g00570 Heat shock transcription factor 8226 18476 28726
Re06.g00580 Uncharacterized protein 8227 18477 28727 Re06.g00590 R3H domain protein, putative 8228 18478 28728
Re06.g00600 hypothetical protein 8229 18479 28729
Re06.g00610 Uncharacterized protein Fragment 8230 18480 28730
Re06.g00620 hypothetical protein 8231 18481 28731
Re06.g00630 hypothetical protein 8232 18482 28732
Re06.g00640 Histone H2A.Z 8233 18483 28733
Re06.g00650 hypothetical protein 8234 18484 28734
Phosphate transporter (Pho88),
Re06.g00660 putative 8235 18485 28735
Glyceraldehyde-3-phosphate
Re06.g00670 dehydrogenase EC=1.2.1.12 8236 18486 28736
Re06.g00680 Histone deacetylase hdal 8237 18487 28737
N-arginine dibasic convertase
NRD1 and related Zn2+-dependent
Re06.g00690 endopeptidases 8238 18488 28738
Re06.g00700 Complex: in human 8239 18489 28739
Re06.g00710 Uncharacterized protein 8240 18490 28740
Similar to Sugar transporter STL1
Re06.g00720 acc. no. P39932 8241 18491 28741 31946 33436
Similar to Anhydro-N- acetylmuramic acid kinase acc. no.
Re06.g00730 Q2JK57 8242 18492 28742
Re06.g00740 Lipase 8243 18493 28743 31947 33437
Re06.g00750 Putative uncharacterized protein 8244 18494 28744
Re06.g00760 Predicted protein 8245 18495 28745
Re06.g00770 Dephospho-CoA kinase 8246 18496 28746
Flavin-containing amine oxidase,
Re06.g00780 putative 8247 18497 28747
Thioredoxin reductase Trr1/Trr2,
Re06.g00790 putative 8248 18498 28748
Re06.g00800 Uncharacterized protein 8249 18499 28749
Pheromone processing
Re06.g00810 endoprotease Kex2 8250 18500 28750 31948 33438
Vacuolar targeting protein Atg24,
Re06.g00820 putative 8251 18501 28751
Monooxygenase involved in
Re06.g00830 coenzyme Q 8252 18502 28752
Histidyl-tRNA synthetase,
Re06.g00840 mitochondrial 8253 18503 28753
Re06.g00850 Putative uncharacterized protein 8254 18504 28754
Re06.g00860 Uncharacterized protein 8255 18505 28755
Re06.g00870 Uncharacterized protein 8256 18506 28756
Ubiquitin carboxyl-terminal
Re06.g00880 hydrolase EC=3.4.19.12 8257 18507 28757
Re06.g00890 Uncharacterized protein 8258 18508 28758 31949 33439
Re06.g00900 Uncharacterized protein 8259 18509 28759 31950 33440
Re06.g00910 Putative uncharacterized protein 8260 18510 28760
Re06.g00920 Dynactin subunit 8261 1851 1 28761
Re06.g00930 Uncharacterized protein 8262 18512 28762 Re06.g00940 hypothetical protein 8263 18513 28763
Re06.g00950 Cytochrome P450 8264 18514 28764
Re06.g00960 Uncharacterized protein 8265 18515 28765
Re06.g00970 Uncharacterized protein 8266 18516 28766
Methyl malonate-semialdehyde
Re06.g00980 dehydrogenase, mitochondrial 8267 18517 28767 31951 33441
Re06.g00990 Calnexin 8268 18518 28768 31952 33442
Methylthioribulose-1 -phosphate
Re06.g01000 dehydratase EC=4.2.1.109 8269 18519 28769
Re06.g01010 Similar to human sorting nexin-1 8270 18520 28770
Re06.g01020 Uncharacterized protein 8271 18521 28771
Re06.g01030 Pc22g02750 protein 8272 18522 28772 31953 33443
Ubiquitination network signaling
Re06.g01040 protein, putative 8273 18523 28773
Re06.g01050 hypothetical protein 8274 18524 28774
Re06.g01060 Uncharacterized protein 8275 18525 28775
Re06.g01070 LYR family protein 8276 18526 28776
SAM binding motif containing
Re06.g01080 protein 8277 18527 28777
Re06.g01090 Uncharacterized protein 8278 18528 28778
Re06.g01 100 Transcription factor, putative 8279 18529 28779
Re06.g01 1 10 Lysophospholipase, putative 8280 18530 28780
tRNA (Adenine-N(1 )-)-
Re06.g01 120 methyltransferase 8281 18531 28781 31954 33444
Phosphoserine phosphatase,
Re06.g01 130 putative 8282 18532 28782
Re06.g01 140 Phosphoesterase 8283 18533 28783
Re06.g01 150 Putative uncharacterized protein 8284 18534 28784
Re06.g01 160 Putative uncharacterized protein 8285 18535 28785 31955 33445
Copper-transporting ATPase,
Re06.g01 170 putative 8286 18536 28786
COP9 signalosome subunit 7
Re06.g01 180 (CsnG), putative 8287 18537 28787
Re06.g01 190 RGS domain protein 8288 18538 28788
Histone acetyltransferase (Gcn5),
Re06.g01200 putative 8289 18539 28789
Re06.g01210 Uncharacterized protein 8290 18540 28790
Re06.g01220 DNA repair protein Rad50 8291 18541 28791
Re06.g01230 Predicted protein 8292 18542 28792
Phosphoribosyl-aminoimidazole
Re06.g01240 carboxylase 8293 18543 28793
Re06.g01250 hypothetical protein 8294 18544 28794
Re06.g01260 hypothetical protein 8295 18545 28795
Re06.g01270 Uncharacterized protein 8296 18546 28796
Re06.g01280 YagE family protein 8297 18547 28797
C2H2 finger domain protein,
Re06.g01290 putative 8298 18548 28798
Re06.g01300 hypothetical protein 8299 18549 28799
Re06.g01310 3-demethylubiquinone-9 3- 8300 18550 28800 methyltransferase
Re06.g01320 Putative uncharacterized protein 8301 18551 28801
Re06.g01330 Putative uncharacterized protein 8302 18552 28802
Re06.g01340 Putative uncharacterized protein 8303 18553 28803
Re06.g01350 Uncharacterized protein 8304 18554 28804
CaaX farnesyltransferase beta
Re06.g01360 subunit Rami 8305 18555 28805
Re06.g01370 C6 finger domain protein 8306 18556 28806
Re06.g01380 Polyubiquitin UbiD/Ubi4, putative 8307 18557 28807
RING and UBP finger domain
Re06.g01390 protein, putative 8308 18558 28808
Potassium/sodium efflux P-type
Re06.g01400 ATPase, fungal-type, putative 8309 18559 28809
Re06.g01410 Uncharacterized protein 8310 18560 28810
Re06.g01420 hypothetical protein 831 1 18561 2881 1 31956 33446
Aspartate aminotransferase
Re06.g01430 EC=2.6.1.1 8312 18562 28812
DNA binding protein SART-1 ,
Re06.g01440 putative 8313 18563 28813
Mitochondrial peptidyl-tRNA
Re06.g01450 hydrolase Pth2, putative 8314 18564 28814
Re06.g01460 Putative uncharacterized protein 8315 18565 28815 31957 33447
Re06.g01470 Uncharacterized protein 8316 18566 28816 31958 33448
Re06.g01480 Homocitrate synthase 8317 18567 28817
Glutamate
decarboxylase/sphingosine
Re06.g01490 phosphate lyase 8318 18568 28818
Mitochondrial 54S ribosomal
Re06.g01500 protein YmL33 8319 18569 28819
Exocyst complex component Sec6,
Re06.g01510 putative 8320 18570 28820
Re06.g01520 Uncharacterized protein 8321 18571 28821
Mitochondrial chaperone Frataxin,
Re06.g01530 putative 8322 18572 28822
Putative uncharacterized protein
Re06.g01540 An04g06150 8323 18573 28823
Transcription regulator BDF1 ,
Re06.g01550 putative 8324 18574 28824
Small nucleolar ribonucleoprotein
complex component (Utp5),
Re06.g01560 putative 8325 18575 28825
Re06.g01570 WD domain-containing protein 8326 18576 28826
Geranylgeranyl transferae type II
Re06.g01580 alpha subunit 8327 18577 28827
Re06.g01590 GTPase activating protein 8328 18578 28828
Re06.g01600 Putative uncharacterized protein 8329 18579 28829
Re06.g01610 Predicted protein 8330 18580 28830 31959 33449
Re06.g01620 Uncharacterized protein 8331 18581 28831
Re06.g01630 hypothetical protein 8332 18582 28832
Re06.g01640 Putative uncharacterized protein 8333 18583 28833 Re06.g01650 Uncharacterized protein 8334 18584 28834
Re06.g01660 Uncharacterized protein 8335 18585 28835
Histone acetylase complex subunit
Re06.g01670 MRG15-2 8336 18586 28836
Re06.g01680 Putative uncharacterized protein 8337 18587 28837
Iron-sulfur cluster assembly
Re06.g01690 accessory protein Isa1 , putative 8338 18588 28838
Conserved membrane protein,
Re06.g01700 putative 8339 18589 28839
Re06.g01710 Vesicle transport v-snare protein 8340 18590 28840
Re06.g01720 RuvB-like helicase 1 EC=3.6.4.12 8341 18591 28841
Re06.g01730 50S ribosomal protein L24 8342 18592 28842 31960 33450
Alpha- 1 ,6-mannosyltransferase
Re06.g01740 subunit 8343 18593 28843
Steroid alpha reductase family
Re06.g01750 protein 8344 18594 28844
Re06.g01760 Fatty acid oxygenase 8345 18595 28845
Ubiquitin-protein ligase (Tom1 ),
Re06.g01770 putative 8346 18596 28846
Phosphoribosyl diphosphate
synthase isoform 4
Re06.g01780 (AFlLorthologue AFUA_4G10790) 8347 18597 28847
Re06.g01790 40S ribosomal protein S6 8348 18598 28848
Re06.g01800 Uncharacterized protein 8349 18599 28849 31961 33451
HMG box transcriptional regulator,
Re06.g01810 putative 8350 18600 28850 31962 33452
Re06.g01820 SNF2 family helicase 8351 18601 28851
Re06.g01830 Putative uncharacterized protein 8352 18602 28852
Alpha-aminoadipate reductase
Re06.g01840 large subunit, putative 8353 18603 28853
Re06.g01850 Uncharacterized protein 8354 18604 28854
Re06.g01860 Xanthine dehydrogenase 8355 18605 28855
Re06.g01870 Uncharacterized protein 8356 18606 28856
Re06.g01880 Putative uncharacterized protein 8357 18607 28857
Re06.g01890 hypothetical protein 8358 18608 28858
Re06.g01900 hypothetical protein 8359 18609 28859
Re06.g01910 Putative uncharacterized protein 8360 18610 28860
Kynurenine aminotransferase,
Re06.g01920 glutamine transaminase K 8361 1861 1 28861
Re06.g01930 AAA family ATPase, putative 8362 18612 28862
Re06.g01940 Uncharacterized protein 8363 18613 28863
Cell division control protein Cdc31 ,
Re06.g01950 putative 8364 18614 28864
ADAM family of metalloprotease
Re06.g01960 ADM-B 8365 18615 28865 31963 33453
Re06.g01970 DNA polymerase iota, putative 8366 18616 28866
Re06.g01980 Putative uncharacterized protein 8367 18617 28867
Re06.g01990 C2 domain protein 8368 18618 28868
Re06.g02000 Putative uncharacterized protein 8369 18619 28869 Re06.g02010 Acetate--CoA ligase 8370 18620 28870
Re06.g02020 Nucleoporin SONB, putative 8371 18621 28871
Re06.g02030 MFS transporter, putative 8372 18622 28872
NADH-ubiquinone oxidoreductase,
Re06.g02040 subunit F, putative EC= .6.5.3 8373 18623 28873 31964 33454
Re06.g02050 Uncharacterized protein 8374 18624 28874 31965 33455
Re06.g02060 Glycerate dehydrogenase 8375 18625 28875
Re06.g02070 Phosphoglycerate mutase, putative 8376 18626 28876
Re06.g02080 Putative uncharacterized protein 8377 18627 28877
Oligopeptide transporter, OPT
Re06.g02090 family, putative 8378 18628 28878
Benzoate 4-monooxygenase
Re06.g02100 cytochrome P450, putative 8379 18629 28879
Re06.g021 10 SH3 domain protein 8380 18630 28880
Cell division protein kinase (Ctk1 ),
Re06.g02120 putative 8381 18631 28881
Re06.g02130 Putative uncharacterized protein 8382 18632 28882
Re06.g02140 M protein repeat protein 8383 18633 28883
Re06.g02150 Ribosome biogenesis protein Nhp2 8384 18634 28884
Re06.g02160 NRPS-like enzyme 8385 18635 28885
Re06.g02170 hypothetical protein 8386 18636 28886
Re06.g02180 Transketolase EC=2.2.1.1 8387 18637 28887
Acetate regulatory DNA binding
Re06.g02190 protein FacB 8388 18638 28888
Re06.g02200 SET domain protein 8389 18639 28889
Re06.g02210 Putative uncharacterized protein 8390 18640 28890
Re06.g02220 GTP-binding protein 8391 18641 28891
Re06.g02230 Uncharacterized protein 8392 18642 28892
Re06.g02240 Putative uncharacterized protein 8393 18643 28893
Re06.g02250 hypothetical protein 8394 18644 28894
Re06.g02260 hypothetical protein 8395 18645 28895
Re06.g02270 Putative uncharacterized protein 8396 18646 28896
NADH-dependent flavin
Re06.g02280 oxidoreductase, putative 8397 18647 28897
Re06.g02290 Spermidine synthase 8398 18648 28898
Prohibitin complex subunit Phb1 ,
Re06.g02300 putative 8399 18649 28899 31966 33456
Re06.g02310 Uncharacterized protein 8400 18650 28900
Re06.g02320 Predicted protein 8401 18651 28901
Re06.g02330 Predicted protein 8402 18652 28902
Re06.g02340 Putative uncharacterized protein 8403 18653 28903
Re06.g02350 Putative Sugar transporter STL1 8404 18654 28904 31967 33457
Putative anhydro-n-acetylmuramic
Re06.g02360 acid kinase protein 8405 18655 28905
Cell wall proline rich protein,
Re06.g02370 putative 8406 18656 28906
Re06.g02380 Uncharacterized protein 8407 18657 28907
Phosphotyrosyl phosphatase
Re06.g02390 activator 8408 18658 28908 Re06.g02400 Putative uncharacterized protein 8409 18659 28909
Re06.g02410 Nuclear protein, putative 8410 18660 28910
Re06.g02420 Uncharacterized protein 841 1 18661 2891 1
Re06.g02430 hypothetical protein 8412 18662 28912
Re06.g02440 Tubulin gamma chain 8413 18663 28913
Re06.g02450 DCG1 -like protein, putative 8414 18664 28914
Re06.g02460 Aflatoxin B1 -aldehyde reductase 8415 18665 28915
Re06.g02470 hypothetical protein 8416 18666 28916
Putative uncharacterized protein
Re06.g02480 An18g01090 EC=3.1.1.5 Precursor 8417 18667 28917 31968 33458
Putative aldehyde dehydrogenase
Re06.g02490 protein 8418 18668 28918
Re06.g02500 hypothetical protein 8419 18669 28919 31969 33459
Re06.g02510 Reverse transcriptase, putative 8420 18670 28920
Re06.g02520 Uncharacterized protein 8421 18671 28921
Re06.g02530 3-oxoadipate enol-lactonase 8422 18672 28922
Re06.g02540 Salicylate hydroxylase 8423 18673 28923 31970 33460
Re06.g02550 hypothetical protein 8424 18674 28924
Re06.g02560 Uncharacterized protein 8425 18675 28925
Re06.g02570 Uncharacterized protein 8426 18676 28926
Re06.g02580 Uncharacterized protein 8427 18677 28927
Re06.g02590 hypothetical protein 8428 18678 28928
Re06.g02600 Uncharacterized protein 8429 18679 28929
Re06.g02610 DUF6 domain protein, putative 8430 18680 28930 31971 33461
Re06.g02620 Arp2/3 complex subunit 8431 18681 28931
NAD binding domain of 6-
Re06.g02630 phosphogluconate dehydrogenase 8432 18682 28932
Re06.g02640 hypothetical protein 8433 18683 28933
Re06.g02650 BZIP transcription factor, putative 8434 18684 28934
Re06.g02660 GTP cyclo hydrolase II, putative 8435 18685 28935
Re06.g02670 SAGA complex component 8436 18686 28936
Mannose-6-phosphate isomerase
Re06.g02680 EC=5.3.1.8 8437 18687 28937
Re06.g02690 hypothetical protein 8438 18688 28938
Re06.g02700 Putative uncharacterized protein 8439 18689 28939
Re06.g02710 Allantoate permease, putative 8440 18690 28940
Re06.g02720 Putative uncharacterized protein 8441 18691 28941 31972 33462
NAD dependent
Re06.g02730 epimerase/dehydratase, putative 8442 18692 28942
Putative uncharacterized protein
Re06.g02740 An1 1 g01270 8443 18693 28943
Re06.g02750 hypothetical protein 8444 18694 28944
Putative uncharacterized protein
Re06.g02760 An1 1 g01260 8445 18695 28945
Re06.g02770 Predicted protein 8446 18696 28946
Re06.g02780 Putative uncharacterized protein 8447 18697 28947
Re06.g02790 Putative uncharacterized protein 8448 18698 28948
Re06.g02800 hypothetical protein 8449 18699 28949
Re06.g02810 Uncharacterized protein 8450 18700 28950 Re06.g02820 hypothetical protein 8451 18701 28951
Re06.g02830 hypothetical protein 8452 18702 28952
Re06.g02840 hypothetical protein 8453 18703 28953
1 -phosphatidylinositol-4,5-
Re06.g02850 bisphosphate phosphodiesterase 1 8454 18704 28954
Re06.g02860 Coatomer subunit epsilon, putative 8455 18705 28955
Re06.g02870 hypothetical protein 8456 18706 28956
Re06.g02880 Putative transporter 8457 18707 28957
Re06.g02890 Putative uncharacterized protein 8458 18708 28958
Re06.g02900 Amidohydrolase, putative 8459 18709 28959
NAD dependent
epimerase/dehydratase, putative
Re06.g02910 (AFlLorthologue AFUA_7G00180) 8460 18710 28960
Nonsense transcript regulator,
Re06.g02920 putative 8461 1871 1 28961
U3 small nucleolar
ribonucleoprotein protein IMP4,
Re06.g02930 putative 8462 18712 28962
Re06.g02940 BRCT domain protein 8463 18713 28963
N-(5'-phosphoribosyl)anthranilate
Re06.g02950 isomerase 8464 18714 28964
Re06.g02960 Nucleoporin (Nup184), putative 8465 18715 28965
Re06.g02970 4-coumarate-CoA ligase, putative 8466 18716 28966 31973 33463
Re06.g02980 hypothetical protein 8467 18717 28967
Re06.g02990 hypothetical protein 8468 18718 28968 31974 33464
G-protein complex alpha subunit
Re06.g03000 GpaA/FadA 8469 18719 28969
Re06.g03010 Predicted protein 8470 18720 28970
Re06.g03020 hypothetical protein 8471 18721 28971
Re06.g03030 Smr domain protein 8472 18722 28972
Re06.g03040 hypothetical protein 8473 18723 28973
Geranylgeranyl diphosphate
Re06.g03050 synthase 8474 18724 28974
Re06.g03060 Cell division control protein 14 8475 18725 28975
Re06.g03070 Uncharacterized protein 8476 18726 28976
Mitochondrial outer membrane
Re06.g03080 protein (Sam35), putative 8477 18727 28977
Re06.g03090 Uncharacterized protein 8478 18728 28978
Re06.g03100 DUF543 domain protein 8479 18729 28979
Re06.g031 10 Uncharacterized protein 8480 18730 28980
Re06.g03120 hypothetical protein 8481 18731 28981
Re06.g03130 Uridine permease Fui1 , putative 8482 18732 28982
Re06.g03140 Putative uncharacterized protein 8483 18733 28983
Remark: probable zinc-finger
Re06.g03150 protein 8484 18734 28984
Re06.g03160 Putative uncharacterized protein 8485 18735 28985
Re06.g03170 C2H2 transcription factor 8486 18736 28986
Re06.g03180 hypothetical protein 8487 18737 28987
Re06.g03190 Possible dual specificity protein 8488 18738 28988 phosphatase 3
Re06.g03200 Uncharacterized protein 8489 18739 28989
SNF2 family helicase/ATPase
Re06.g03210 PasG 8490 18740 28990
Re06.g03220 Cytoskeletal adaptor protein SagA 8491 18741 28991
Re06.g03230 hypothetical protein 8492 18742 28992
Re06.g03240 Putative uncharacterized protein 8493 18743 28993
Re06.g03250 Putative uncharacterized protein 8494 18744 28994
Re06.g03260 Uncharacterized protein 8495 18745 28995
Re06.g03270 Cullin 8496 18746 28996
Re06.g03280 Phosphorylase EC=2.4.1.1 8497 18747 28997
Re06.g03290 hypothetical protein 8498 18748 28998
G protein complex alpha subunit
Re06.g03300 GpaB 8499 18749 28999
Re06.g03310 MAP kinase SakA EC=2.7.1 1.24 8500 18750 29000
Re06.g03320 Putative uncharacterized protein 8501 18751 29001
Re06.g03330 Laccase iv 8502 18752 29002 31975 33465
Related to non-hemolytic
Re06.g03340 phospholipase C 8503 18753 29003 31976 33466
Re06.g03350 Putative uncharacterized protein 8504 18754 29004
Re06.g03360 ABC fatty acid transporter, putative 8505 18755 29005 31977 33467
Cell wall biogenesis protein Mhp1 ,
Re06.g03370 putative 8506 18756 29006
Re06.g03380 60S ribosomal protein L5 8507 18757 29007
Re06.g03390 Epoxide hydrolase, putative 8508 18758 29008
Re06.g03400 Putative uncharacterized protein 8509 18759 29009
Re06.g03410 Putative uncharacterized protein 8510 18760 29010
Re06.g03420 Predicted protein 851 1 18761 2901 1
Re06.g03430 Cell surface protein Mas1 , putative 8512 18762 29012 31978 33468
Re06.g03440 Putative uncharacterized protein 8513 18763 29013
Re06.g03450 Nitrate transporter CrnA 8514 18764 29014
Re06.g03460 Nitrite reductase NiiA 8515 18765 29015
Re06.g03470 Nitrate reductase 8516 18766 29016
Gamma-tubulin complex
Re06.g03480 component GCP6, putative 8517 18767 29017
Re06.g03490 Putative uncharacterized protein 8518 18768 29018
Isocitrate dehydrogenase, NAD-
Re06.g03500 dependent 8519 18769 29019
Exocyst complex component Sec5,
Re06.g03510 putative 8520 18770 29020
Re06.g03520 Putative uncharacterized protein 8521 18771 29021
Re06.g03530 Uncharacterized protein 8522 18772 29022
Adenylyl cyclase-associated
Re06.g03540 protein 8523 18773 29023
PfkB family carbohydrate kinase
Re06.g03550 (Mak32), putative 8524 18774 29024
Re06.g03560 Putative uncharacterized protein 8525 18775 29025
Mitochondrial 54S ribosomal
Re06.g03570 protein YmL3 8526 18776 29026 Re06.g03580 PBSP domain protein 8527 18777 29027
Re06.g03590 Putative uncharacterized protein 8528 18778 29028 31979 33469
Nonribosomal siderophore peptide
Re06.g03600 synthase SidC 8529 18779 29029
Re06.g03610 Uncharacterized protein 8530 18780 29030
Re06.g03620 Uncharacterized protein 8531 18781 29031
Re06.g03630 Multidrug resistance protein 1 , 2, 3 8532 18782 29032 31980 33470
Re06.g03640 hypothetical protein 8533 18783 29033
Re06.g03650 Rho GTPase activator Rga 8534 18784 29034
Re06.g03660 Uncharacterized protein 8535 18785 29035
Re06.g03670 Putative uncharacterized protein 8536 18786 29036
Mannosylphosphate transferase
Re06.g03680 (Mnn4), putative 8537 18787 29037 31981 33471
Re06.g03690 Zinc metalloproteinase, putative 8538 18788 29038
3-ketoacyl-CoA ketothiolase (Kat1 ),
Re06.g03700 putative 8539 18789 29039
Re06.g03710 Heat shock protein Hsp88 8540 18790 29040
Re06.g03720 Chitin synthase class VI 8541 18791 29041
Re06.g03730 RNA-binding La domain protein 8542 18792 29042
Stress responsive A/B barrel
Re06.g03740 domain protein 8543 18793 29043
RNA binding protein
Re06.g03750 Ligatin/Tma64, putative 8544 18794 29044
Re06.g03760 Putative uncharacterized protein 8545 18795 29045
Membrane-tethered transcription
Re06.g03770 factor (SPT23), putative 8546 18796 29046 31982 33472
Re06.g03780 Uncharacterized protein 8547 18797 29047
Putative cytochrome p450
Re06.g03790 monooxygenase protein 8548 18798 29048
Similarity: belongs to the GAL4
Re06.g03800 zinc binuclear cluster family 8549 18799 29049
Re06.g03810 Oleate delta-12 desaturase 8550 18800 29050
DNA repair protein (Rad57),
Re06.g03820 putative 8551 18801 29051
Re06.g03830 Putative uncharacterized protein 8552 18802 29052
Re06.g03840 hypothetical protein 8553 18803 29053
Re06.g03850 hypothetical protein 8554 18804 29054
Re06.g03860 Sexual development activator VeA 8555 18805 29055
Nuclear RNA binding protein,
Re06.g03870 putative 8556 18806 29056
Re06.g03880 Predicted protein 8557 18807 29057
Re06.g03890 GABA permease, putative 8558 18808 29058
Re06.g03900 Maltose permease, putative 8559 18809 29059
Re06.g03910 Jumonji family transcription factor 8560 18810 29060
Re06.g03920 Carnitine acetyl transferase 8561 1881 1 29061
Re06.g03930 Putative uncharacterized protein 8562 18812 29062
Re06.g03940 hypothetical protein 8563 18813 29063
Re06.g03950 Putative uncharacterized protein 8564 18814 29064 31983 33473
Re06.g03960 Pantothenate transporter, putative 8565 18815 29065 Re06.g03970 Similar to An01g02260 8566 18816 29066
Re06.g03980 C6 transcription factor, putative 8567 18817 29067
Re06.g03990 DUF255 domain protein 8568 18818 29068
Re06.g04000 WD repeat protein 8569 18819 29069
G2/M phase checkpoint control
Re06.g04010 protein Sum2, putative 8570 18820 29070
Re06.g04020 Acyl CoA binding protein, putative 8571 18821 29071
NADH-ubiquinone oxidoreductase,
Re06.g04030 putative EC=1.6.5.3 8572 18822 29072
Re06.g04040 Nucleoporin, putative 8573 18823 29073
Re06.g04050 Predicted protein 8574 18824 29074
Re06.g04060 Transcription factor iws-1 8575 18825 29075
Re06.g04070 Uncharacterized protein 8576 18826 29076
Re06.g04080 Uncharacterized protein 8577 18827 29077 31984 33474
Interferon-induced GTP-binding
Re06.g04090 protein Mx, putative 8578 18828 29078
Re06.g04100 Uncharacterized protein 8579 18829 29079
Re06.g041 10 Putative uncharacterized protein 8580 18830 29080
Re06.g04120 hypothetical protein 8581 18831 29081
Re06.g04130 Uncharacterized protein 8582 18832 29082
Re06.g04140 Protein SEY1 EC=3.6.5.- 8583 18833 29083
Re06.g04150 C6 finger domain protein, putative 8584 18834 29084
Re06.g04160 MFS multidrug transporter, putative 8585 18835 29085
Re06.g04170 Putative uncharacterized protein 8586 18836 29086
Re06.g04180 Putative uncharacterized protein 8587 18837 29087
Re06.g04190 Elongation factor Tu 8588 18838 29088
Translation initiation factor IF3,
Re06.g04200 putative 8589 18839 29089 31985 33475
Re06.g04210 Nucleoside diphosphatase Gda1 8590 18840 29090 31986 33476
Re06.g04220 Uncharacterized protein 8591 18841 29091
Translation initiation factor elF4E,
Re06.g04230 putative 8592 18842 29092
Putative glycoside hydrolase family
Re06.g04240 18 protein 8593 18843 29093 31987 33477
Re06.g04250 Predicted protein 8594 18844 29094
Re06.g04260 Arginine rich protein 8595 18845 29095
NADH-ubiquinone oxidoreductase
Re06.g04270 14 kDa subunit, putative 8596 18846 29096
Re06.g04280 Cation efflux family protein family 8597 18847 29097
RING finger ubiquitin ligase (Tul1 ),
Re06.g04290 putative 8598 18848 29098 31988 33478
Re06.g04300 Glycine cleavage system H protein 8599 18849 29099 31989 33479
Re06.g04310 37S ribosomal protein Mrp17 8600 18850 29100
Re06.g04320 Acyl-CoA thioesterase 8601 18851 29101
Re06.g04330 Putative uncharacterized protein 8602 18852 29102 31990 33480
Re06.g04340 Putative uncharacterized protein 8603 18853 29103
Re06.g04350 Uncharacterized protein 8604 18854 29104
Re06.g04360 Pc12g15150 protein 8605 18855 29105
Re06.g04370 Arrestin domain protein 8606 18856 29106 Re06.g04380 hypothetical protein 8607 18857 29107
Re06.g04390 Putative uncharacterized protein 8608 18858 29108
Nuclear and cytoplasmic
polyadenylated RNA-binding
Re06.g04400 protein publ 8609 18859 29109
Re06.g04410 Putative uncharacterized protein 8610 18860 291 10
Glutamine amidotransferase,
Re06.g04420 putative 861 1 18861 291 1 1
Mitochondrial dynamin GTPase
Re06.g04430 (Msp1 ), putative 8612 18862 291 12
Re06.g04440 Alternative NADH-dehydrogenase 8613 18863 291 13
Re06.g04450 hypothetical protein 8614 18864 291 14
Re06.g04460 Mucin, putative 8615 18865 291 15 31991 33481
Putative capsular associated
Re06.g04470 protein 8616 18866 291 16
Re06.g04480 Transposase 8617 18867 291 17
Re06.g04490 50S ribosomal subunit protein L15 8618 18868 291 18 31992 33482
Re06.g04500 Protein kinase, putative 8619 18869 291 19
Re06.g04510 SH3 domain protein, putative 8620 18870 29120
Re06.g04520 Uncharacterized protein 8621 18871 29121
Re06.g04530 PQ loop repeat protein 8622 18872 29122 31993 33483
Serine palmitoyltransferase 2,
Re06.g04540 putative EC=2.3.1.50 8623 18873 29123
Re06.g04550 Acetoacetyl-CoA synthase 8624 18874 29124
Re06.g04560 Mitochondrial processing peptidase 8625 18875 29125
Mitochondrial import receptor
Re06.g04570 subunit tom22 8626 18876 29126
Re06.g04580 Putative uncharacterized protein 8627 18877 29127
Re06.g04590 Putative uncharacterized protein 8628 18878 29128
Phosphatase-like protein (PTPLA),
Re06.g04600 putative 8629 18879 29129 31994 33484
Re06.g04610 Putative uncharacterized protein 8630 18880 29130
Small nuclear ribonucleoprotein
Re06.g04620 SmD3, putative 8631 18881 29131
Re06.g04630 Uncharacterized protein 8632 18882 29132
Homeobox transcription factor
Re06.g04640 (RfeB), putative 8633 18883 29133
Haloacid dehalogenase-like
Re06.g04650 hydrolase, putative 8634 18884 29134
Re06.g04660 Transcription factor RfeF, putative 8635 18885 29135
Signal recognition particle protein,
Re06.g04670 putative 8636 18886 29136 31995 33485
Re06.g04680 Uncharacterized protein 8637 18887 29137
Re06.g04690 Putative uncharacterized protein 8638 18888 29138
Re06.g04700 Dienelactone hydrolase, putative 8639 18889 29139
Re06.g04710 Uncharacterized protein 8640 18890 29140
Re06.g04720 Transcription factor AmyR 8641 18891 29141
Glucoamylase EC=3.2.1.3
Re06.g04740 Precursor 8642 18892 29142 31996 33486 Re06.g04750 Alpha-amylase 8643 18893 29143 31997 33487
Function: Tto1 can transpose
autonomously through reverse
transcription EC=2.7.7.49
EC=2.7.7.49 EC=2.7.7.49
Re06.g04760 EC=2.7.7.49 8644 18894 29144
Homeobox transcription factor,
Re06.g04770 putative 8645 18895 29145
Re06.g04780 C6 zinc finger domain protein 8646 18896 29146
Re06.g04790 FAD binding domain protein 8647 18897 29147
Re06.g04800 Class I alpha-mannosidase 8648 18898 29148
Re06.g04810 Putative uncharacterized protein 8649 18899 29149
Re06.g04820 Calmodulin 8650 18900 29150
Re06.g04830 SNARE complex subunit 8651 18901 29151
Re06.g04840 Uncharacterized protein 8652 18902 29152
Re06.g04850 Clathrin light chain 8653 18903 29153
Re06.g04860 Hsp90 co-chaperone Cdc37 8654 18904 29154
Re06.g04870 ABC multidrug transporter Mdr2 8655 18905 29155
Re06.g04880 Nucleoside transporter family 8656 18906 29156
Re06.g04890 Putative uncharacterized protein 8657 18907 29157
Mitochondrial distribution and
Re06.g04900 morphology protein 34 8658 18908 29158
Re06.g04910 Putative uncharacterized protein 8659 18909 29159
Re06.g04920 UbiE/COQ5 methyltransferase 8660 18910 29160
Re06.g04930 Putative uncharacterized protein 8661 1891 1 29161
Re06.g04940 Uncharacterized protein 8662 18912 29162
Re06.g04950 Putative uncharacterized protein 8663 18913 29163 31998 33488
Cell wall biogenesis protein
Re06.g04960 Ecm15, putative 8664 18914 29164
Re06.g04970 Putative uncharacterized protein 8665 18915 29165
Re06.g04980 Putative uncharacterized protein 8666 18916 29166
Re06.g04990 hypothetical protein 8667 18917 29167
Re06.g05000 Uncharacterized protein 8668 18918 29168 31999 33489
Function: Tto1 can transpose
autonomously through reverse
transcription EC=2.7.7.49
EC=2.7.7.49 EC=2.7.7.49
Re06.g05010 EC=2.7.7.49 8669 18919 29169
Re06.g05020 hypothetical protein 8670 18920 29170
Re06.g05030 Uncharacterized protein 8671 18921 29171
Re06.g05040 Kynureninase 2 EC=3.7.1.3 8672 18922 29172
Indoleamine 2,3-dioxygenase
Re06.g05050 pyrrole 2,3-dioxygenase 8673 18923 29173
Putative uncharacterized protein
Re06.g05060 Fragment 8674 18924 29174
Histone acetyltransferase subunit
Re06.g05070 (Yaf9), putative 8675 18925 29175
Re06.g05080 Uncharacterized protein 8676 18926 29176
Re06.g05090 SYF2 splicing factor domain 8677 18927 29177 protein
Re06.g05100 Putative uncharacterized protein 8678 18928 29178
Re06.g051 10 Uncharacterized protein 8679 18929 29179
Re06.g05120 Uncharacterized protein 8680 18930 29180
Re06.g05130 Putative uncharacterized protein 8681 18931 29181
Re06.g05140 50S ribosomal protein L12 8682 18932 29182
Re06.g05150 hypothetical protein 8683 18933 29183 32000 33490
Re06.g05160 hypothetical protein 8684 18934 29184
T-complex protein 1 , theta subunit,
Re06.g05170 putative 8685 18935 29185
Re06.g05180 hypothetical protein 8686 18936 29186
Re06.g05190 hypothetical protein 8687 18937 29187
Re06.g05200 hypothetical protein 8688 18938 29188
Re06.g05210 hypothetical protein 8689 18939 29189
von Willebrand and RING finger
Re06.g05220 domain protein 8690 18940 29190
Re06.g05230 Spap14e8.04 protein 8691 18941 29191
Pyruvate dehydrogenase E1
component alpha subunit, putative
Re06.g05240 EC=1.2.4.1 8692 18942 29192 32001 33491
Re06.g05250 Uncharacterized protein 8693 18943 29193
Mitochondrial 37S ribosomal
Re06.g05260 protein NAM9 8694 18944 29194
Re06.g05270 Putative uncharacterized protein 8695 18945 29195
Re06.g05280 hypothetical protein 8696 18946 29196
Re06.g05290 DNA repair protein Rad26, putative 8697 18947 29197
Re06.g05300 Phosphatidate cytidylyltransferase 8698 18948 29198
Re06.g05310 Cyclin, putative 8699 18949 29199
Glutathione-S-transferase theta,
Re06.g05320 GST, putative 8700 18950 29200
Phosphotransferase enzyme family
Re06.g05330 protein 8701 18951 29201
Re06.g05340 Armadillo repeat protein 8702 18952 29202
Cyclin-dependent protein kinase
Re06.g05350 regulator Pho80 8703 18953 29203 32002 33492
Re06.g05360 hypothetical protein 8704 18954 29204
tRNA-specific adenosine-34
Re06.g05370 deaminase subunit Tad3, putative 8705 18955 29205
Re06.g05380 Predicted protein 8706 18956 29206
Re06.g05390 Uncharacterized protein 8707 18957 29207
Export control protein CHS7-like,
Re06.g05400 putative 8708 18958 29208
Re06.g05410 Predicted protein 8709 18959 29209
Dienelactone hydrolase family
Re06.g05420 protein 8710 18960 29210
Re06.g05430 Alcohol dehydrogenase 871 1 18961 2921 1
Re06.g05440 Putative uncharacterized protein 8712 18962 29212 32003 33493
Re06.g05450 Uncharacterized protein 8713 18963 29213
Re06.g05460 Pathway: STS1 of S. pombe is 8714 18964 29214 involved in ergosterol biosynthesis
RING finger domain protein
Re06.g05470 (Rnfl O), putative 8715 18965 29215
Ubiquitin carboxyl-terminal
Re06.g05480 hydrolase EC=3.4.19.12 8716 18966 29216
Re06.g05490 Ribonuclease H, putative 8717 18967 29217
Re06.g05500 Na/H antiporter, putative 8718 18968 29218
Re06.g05510 Pantothenate transporter, putative 8719 18969 29219
Re06.g05520 Dimethylaniline monooxygenase 8720 18970 29220 32004 33494
Alpha-ketoglutarate-dependent
Re06.g05530 taurine dioxygenase 8721 18971 29221
Re06.g05540 Mitochondrial cytochrome b2 8722 18972 29222 32005 33495
Re06.g05550 Uncharacterized protein 8723 18973 29223
Re06.g05560 Uncharacterized protein 8724 18974 29224
Re06.g05570 6-phosphofructo-2-kinase 1 8725 18975 29225
Re06.g05580 Thioredoxin, putative 8726 18976 29226
Re06.g05590 hypothetical protein 8727 18977 29227
Re06.g05600 Pc22g 16670 protein 8728 18978 29228
Re06.g05610 Putative uncharacterized protein 8729 18979 29229 32006 33496
Re06.g05620 Putative uncharacterized protein 8730 18980 29230
Re06.g05630 hypothetical protein 8731 18981 29231
Re06.g05640 SPX domain protein 8732 18982 29232
Re06.g05650 Uncharacterized protein 8733 18983 29233
Re06.g05660 Uncharacterized protein 8734 18984 29234
Re06.g05670 Uncharacterized protein 8735 18985 29235
Re06.g05680 Uncharacterized protein 8736 18986 29236 32007 33497
Dihydroxy acid dehydratase,
Re06.g05690 putative 8737 18987 29237
Re06.g05700 Cytochrome P450 8738 18988 29238
Re06.g05710 RNA12 protein, putative 8739 18989 29239
Re06.g05720 Putative uncharacterized protein 8740 18990 29240
Glutamate synthase Glt1 , putative
Re06.g05730 EC=1.4.1.14 8741 18991 29241
Re06.g05740 Putative uncharacterized protein 8742 18992 29242
Re06.g05750 V-SNARE 8743 18993 29243
Re06.g05760 hypothetical protein 8744 18994 29244
Molecular chaperone Hsp70
Re06.g05770 EC=1.3.1.74 8745 18995 29245
Re06.g05780 Mitochondrial carrier protein 8746 18996 29246
Autophagy-related protein 8
Re06.g05790 Precursor 8747 18997 29247
DNA-directed RNA polymerase
Re06.g05800 EC=2.7.7.6 8748 18998 29248
Coproporphyrinogen III oxidase,
Re06.g05810 putative EC=1.3.3.3 8749 18999 29249
Microtubule binding protein
Re06.g05820 HOOK3, putative 8750 19000 29250
Re06.g05830 Uncharacterized protein 8751 19001 29251 32008 33498
Re06.g05840 mRNA cleavage factor complex 8752 19002 29252 component Pcf1 1 , putative
Catalytic activity: dimeric
dihydrodiol dehydrogenases
Re06.g05850 EC=1.3.1.20 8753 19003 29253
Re06.g05860 Adenylate kinase EC=2.7.4.3 8754 19004 29254
26S proteasome regulatory particle
Re06.g05870 subunit Rpn8, putative 8755 19005 29255 32009 33499
Re06.g05880 Uncharacterized protein 8756 19006 29256
Re06.g05890 Putative uncharacterized protein 8757 19007 29257
Re06.g05900 Peroxin 16 8758 19008 29258
Re06.g05910 Uncharacterized protein 8759 19009 29259
Re06.g05920 Cupin domain protein 8760 19010 29260
Re06.g05930 Putative uncharacterized protein 8761 1901 1 29261 32010 33500
Cell polarity protein (Alp1 1 ),
Re06.g05940 putative 8762 19012 29262
Re06.g05950 Putative uncharacterized protein 8763 19013 29263
Re06.g05960 MYB DNA-binding domain protein 8764 19014 29264
Re06.g05970 hypothetical protein 8765 19015 29265 3201 1 33501
Re06.g05980 hypothetical protein 8766 19016 29266
Re06.g05990 hypothetical protein 8767 19017 29267
Re06.g06000 Uncharacterized protein 8768 19018 29268
Re06.g06010 F-box domain protein 8769 19019 29269
Re06.g06020 Zinc knuckle domain protein 8770 19020 29270
Re06.g06030 Uncharacterized protein 8771 19021 29271
Re06.g06040 Putative uncharacterized protein 8772 19022 29272
Re06.g06050 Uncharacterized protein 8773 19023 29273
Re06.g06060 Uncharacterized protein 8774 19024 29274
Cytokinesis regulator (Byr4),
Re06.g06070 putative 8775 19025 29275
Re06.g06080 hypothetical protein 8776 19026 29276
Re06.g06090 Uncharacterized protein 8777 19027 29277
Re06.g06100 hypothetical protein 8778 19028 29278 32012 33502
ER lumen protein retaining
Re06.g061 10 receptor 8779 19029 29279
Re06.g06120 Putative uncharacterized protein 8780 19030 29280
Re06.g06130 PSP family protein 8781 19031 29281
Re06.g06140 Uncharacterized protein 8782 19032 29282
Re06.g06150 Nucleolar RNAse III, putative 8783 19033 29283
Re06.g06160 Putative uncharacterized protein 8784 19034 29284
Re06.g06170 hypothetical protein 8785 19035 29285
Re06.g06180 hypothetical protein 8786 19036 29286
Re06.g06190 hypothetical protein 8787 19037 29287
Re06.g06200 Putative uncharacterized protein 8788 19038 29288
Re06.g06210 Putative uncharacterized protein 8789 19039 29289
Re06.g06220 Putative uncharacterized protein 8790 19040 29290
Re06.g06230 Putative uncharacterized protein 8791 19041 29291
Re06.g06240 Uncharacterized protein 8792 19042 29292
Re06.g06250 Uncharacterized protein 8793 19043 29293
Re06.g06260 Putative uncharacterized protein 8794 19044 29294 Re06.g06270 Putative uncharacterized protein 8795 19045 29295
Putative uncharacterized protein
Re06.g06280 Fragment 8796 19046 29296
Re06.g06290 hypothetical protein 8797 19047 29297
Re06.g06300 hypothetical protein 8798 19048 29298
Re06.g06310 Putative uncharacterized protein 8799 19049 29299
Re06.g06320 Putative uncharacterized protein 8800 19050 29300
Re06.g06330 Putative uncharacterized protein 8801 19051 29301
Re06.g06340 hypothetical protein 8802 19052 29302
Re06.g06350 hypothetical protein 8803 19053 29303
SWIRM domain protein Fun19,
Re06.g06360 putative 8804 19054 29304
Putative uncharacterized protein
Re06.g06370 An07g 10420 8805 19055 29305
Extracellular metalloprotease
AO090012001025 EC=3.4.24.-
Re06.g06380 Precursor 8806 19056 29306 32013 33503
Transcription elongation complex
Re06.g06390 subunit (Cdc68) 8807 19057 29307
Mitochondrial carrier protein,
Re06.g06400 putative 8808 19058 29308
Re06.g06410 Putative uncharacterized protein 8809 19059 29309
Re06.g06420 Protein O-mannosyl transferase 8810 19060 29310
Re06.g06430 Secretion related GTPase SrgD 881 1 19061 2931 1
Re06.g06440 Uncharacterized protein 8812 19062 29312
Re06.g06450 Uncharacterized protein 8813 19063 29313
Re06.g06460 Uncharacterized protein 8814 19064 29314
Re06.g06470 Predicted protein 8815 19065 29315 32014 33504
Pumilio-family RNA binding repeat
Re06.g06480 protein 8816 19066 29316
Re06.g06490 Putative uncharacterized protein 8817 19067 29317
RNA polymerase II transcription
Re06.g06500 initiation protein 8818 19068 29318
Re06.g06510 Aminopeptidase, putative 8819 19069 29319
Re06.g06520 GTP-binding protein yptl 8820 19070 29320
Re06.g06530 hypothetical protein 8821 19071 29321
Peroxisomal membrane protein
Re06.g06540 Pmp47 8822 19072 29322
Re06.g06550 WD repeat protein 8823 19073 29323
Re06.g06560 WW domain protein, putative 8824 19074 29324
Re06.g06570 Putative uncharacterized protein 8825 19075 29325 32015 33505
Re06.g06580 AMP-binding enzyme, putative 8826 19076 29326
Re06.g06590 Putative uncharacterized protein 8827 19077 29327
Re06.g06600 Arginine transporter, putative 8828 19078 29328
Re06.g06610 Putative uncharacterized protein 8829 19079 29329
Re06.g06620 O-acetylhomoserine (Thiol)-lyase 8830 19080 29330
Re06.g06630 RNA binding protein Nrd1 8831 19081 29331
Re06.g06640 Citrate synthase 8832 19082 29332
Re06.g06650 Mitochondrial DNA replication 8833 19083 29333 protein (Yhm2), putative
Re06.g06660 Function: HOL1 of S. cerevisiae 8834 19084 29334
Re06.g06670 Uncharacterized protein 8835 19085 29335 32016 33506
Re06.g06680 Putative uncharacterized protein 8836 19086 29336
Re06.g06690 Uncharacterized protein 8837 19087 29337 32017 33507
Re06.g06700 Uncharacterized protein 8838 19088 29338
Re06.g06710 Uncharacterized protein 8839 19089 29339
Ubiquinol-cytochrome C reductase
Re06.g06720 complex core protein 2 8840 19090 29340 32018 33508
DNA directed RNA polymerase III
Re06.g06730 subunit Rpc82, putative 8841 19091 29341
Re06.g06740 Putative uncharacterized protein 8842 19092 29342 32019 33509
Re06.g06750 Tubulin alpha- 1 subunit 8843 19093 29343 32020 33510
Re06.g06760 UBA/TS-N domain protein 8844 19094 29344
Re06.g06770 Pc22g09270 protein 8845 19095 29345
Re06.g06780 Glycosyl hydrolase, putative 8846 19096 29346 32021 3351 1
Putative plasma membrane atpase
Re06.g06790 protein 8847 19097 29347
Re06.g06800 hypothetical protein 8848 19098 29348
Re06.g06810 Putative uncharacterized protein 8849 19099 29349
Re06.g06820 Uncharacterized protein 8850 19100 29350
Origin recognition complex subunit
Re06.g06830 Orc5, putative 8851 19101 29351
Re06.g06840 RNA-binding protein, putative 8852 19102 29352
DNA-directed RNA polymerase III
Re06.g06850 subunit RET1 8853 19103 29353
Re06.g06860 Uncharacterized protein 8854 19104 29354
Re06.g06870 Uncharacterized protein 8855 19105 29355
Ubiquitin fusion degradation protein
Re06.g06880 Ufd1 , putative 8856 19106 29356
Re06.g06890 Putative uncharacterized protein 8857 19107 29357
AAA family ATPase Rvb2/Reptin,
Re06.g06900 putative 8858 19108 29358
Re06.g06910 Paramyosin, putative 8859 19109 29359
Re06.g06920 Uncharacterized protein 8860 191 10 29360 32022 33512
Re06.g06930 Pc22g21850 protein 8861 191 1 1 29361
Re06.g06940 Putative uncharacterized protein 8862 191 12 29362
Fumarylacetoacetate hydrolase
Re06.g06950 family protein 8863 191 13 29363
Re06.g06960 MFS multidrug transporter, putative 8864 191 14 29364
C2H2 type zinc finger domain
Re06.g06970 protein 8865 191 15 29365
Re06.g06980 O-methyltransferase, putative 8866 191 16 29366
Re06.g06990 Putative uncharacterized protein 8867 191 17 29367
Re06.g07000 Hydroxybutyrate dehydrogenase 8868 191 18 29368 32023 33513
Re06.g07010 hypothetical protein 8869 191 19 29369
Re06.g07020 Uncharacterized protein 8870 19120 29370
Re06.g07030 Protein RTA1 , putative 8871 19121 29371
Re06.g07040 Putative uncharacterized protein 8872 19122 29372 Ankyrin repeat domain containing
Re06.g07050 protein 8873 19123 29373
Re06.g07060 Uncharacterized protein 8874 19124 29374
Re06.g07070 hypothetical protein 8875 19125 29375 32024 33514
Re06.g07080 hypothetical protein 8876 19126 29376
Re06.g07090 Putative beta-mannosidase B 8877 19127 29377
Re06.g07100 Alpha-glucosidase 8878 19128 29378
Re06.g071 10 Predicted protein 8879 19129 29379
Re06.g07120 Similar to An14g02830 8880 19130 29380
Re06.g07130 Uncharacterized protein 8881 19131 29381
Re06.g07140 Sugar transporter 8882 19132 29382
Re06.g07150 hypothetical protein 8883 19133 29383 32025 33515
Re06.g07160 Uncharacterized protein 8884 19134 29384
Re06.g07170 hypothetical protein 8885 19135 29385
Re06.g07180 hypothetical protein 8886 19136 29386
Re06.g07190 hypothetical protein 8887 19137 29387
Re06.g07200 hypothetical protein 8888 19138 29388
Re06.g07210 Uncharacterized protein 8889 19139 29389
Re06.g07220 Putative uncharacterized protein 8890 19140 29390
Re06.g07230 hypothetical protein 8891 19141 29391
Re06.g07240 hypothetical protein 8892 19142 29392
Re06.g07250 hypothetical protein 8893 19143 29393
Re06.g07260 Uncharacterized protein 8894 19144 29394
Re06.g07270 hypothetical protein 8895 19145 29395
Re06.g07280 Putative uncharacterized protein 8896 19146 29396
Re06.g07290 ARS binding protein Abp2, putative 8897 19147 29397
Re06.g07300 Putative uncharacterized protein 8898 19148 29398
Re06.g07310 Acid phosphatase, putative 8899 19149 29399 32026 33516
Re06.g07320 Putative uncharacterized protein 8900 19150 29400
Ribosome biogenesis protein
Re06.g07330 BRX1 8901 19151 29401
Re06.g07340 Putative uncharacterized protein 8902 19152 29402
Re06.g07350 F-box domain protein 8903 19153 29403
Re06.g07360 Uncharacterized protein 8904 19154 29404
Re06.g07370 Putative uncharacterized protein 8905 19155 29405
Re06.g07380 Uncharacterized protein 8906 19156 29406 32027 33517
Re06.g07390 Isochorismatase family protein 8907 19157 29407
Re06.g07400 Putative uncharacterized protein 8908 19158 29408
Alpha-galactosidase/alpha-n-
Re06.g07410 acetylgalactosaminidase 8909 19159 29409 32028 33518
Re06.g07420 Putative uncharacterized protein 8910 19160 29410
Re06.g07430 Glutaminyl-tRNA synthetase 891 1 19161 2941 1
Re06.g07440 Uncharacterized protein 8912 19162 29412
Re06.g07450 Putative uncharacterized protein 8913 19163 29413
Re06.g07460 hypothetical protein 8914 19164 29414
Re06.g07470 Zinc-binding oxidoreductase CipB 8915 19165 29415
Aspergillus niger contig
Re06.g07480 An02c0310, genomic contig 8916 19166 29416 32029 33519
Re06.g07490 AlphaN-acetylglucosamine 8917 19167 29417 transferase
Re06.g07500 Putative mfs transporter protein 8918 19168 29418
Re06.g07510 hypothetical protein 8919 19169 29419
Re06.g07520 Short chain dehydrogenase 8920 19170 29420 32030 33520
Re06.g07530 Allantoin permease, putative 8921 19171 29421
Re06.g07540 Putative uncharacterized protein 8922 19172 29422
Re06.g07550 Uncharacterized protein 8923 19173 29423
Re06.g07560 Adenylate-forming enzyme AfeA 8924 19174 29424
Re06.g07570 Putative xylose transporter 8925 19175 29425
Alpha-ketoglutarate-dependent
Re06.g07580 sulfonate dioxygenase 8926 19176 29426
Re06.g07590 Uncharacterized protein 8927 19177 29427
Re06.g07600 Dioxygenase-like protein 8928 19178 29428
Putative monooxygenase-like
Re06.g07610 protein 8929 19179 29429
Putative trihydroxytoluene
Re06.g07620 oxygenase protein 8930 19180 29430
Re06.g07630 Uncharacterized protein Fragment 8931 19181 29431
Re06.g07640 Putative uncharacterized protein 8932 19182 29432
Re06.g07650 Uncharacterized protein 8933 19183 29433
Re06.g07660 Uncharacterized protein 8934 19184 29434
Re06.g07670 Uncharacterized protein 8935 19185 29435
Major facilitator superfamily
Re06.g07680 transporter 8936 19186 29436
Dimethylaniline monooxygenase,
Re06.g07690 putative 8937 19187 29437 32031 33521
Re06.g07700 Putative uncharacterized protein 8938 19188 29438 32032 33522
Re06.g07710 Fungal specific transcription factor 8939 19189 29439
Glycoside hydrolase family 88
Re06.g07720 protein 8940 19190 29440
Re06.g07730 Putative uncharacterized protein 8941 19191 29441 32033 33523
Re06.g07740 Uncharacterized protein 8942 19192 29442
Re06.g07750 Uncharacterized protein 8943 19193 29443
Re06.g07760 Putative uncharacterized protein 8944 19194 29444
Re06.g07770 Putative sugar transporter protein 8945 19195 29445
Re06.g07780 Predicted protein 8946 19196 29446 32034 33524
Re06.g07790 Putative uncharacterized protein 8947 19197 29447 32035 33525
Re06.g07800 Uncharacterized protein 8948 19198 29448 32036 33526
Putative uncharacterized protein
Re06.g07810 Fragment 8949 19199 29449
Re06.g07820 Uncharacterized protein 8950 19200 29450
Re06.g07830 Uncharacterized protein 8951 19201 29451
Fungal specific transcription factor
Re06.g07840 domain-containing protein 8952 19202 29452
Re06.g07850 Putative uncharacterized protein 8953 19203 29453
Re06.g07860 Predicted protein 8954 19204 29454
Re07.g00010 hypothetical protein 8955 19205 29455
Re07.g00020 Putative uncharacterized protein 8956 19206 29456
Re07.g00030 Putative uncharacterized protein 8957 19207 29457 An06g02150 Precursor
Re07.g00040 hypothetical protein 8958 19208 29458
Putative uncharacterized protein
Re07.g00050 Fragment 8959 19209 29459
Re07.g00060 Putative uncharacterized protein 8960 19210 29460
Putative uncharacterized protein
Re07.g00070 Precursor 8961 1921 1 29461 32037 33527
Re07.g00080 Putative uncharacterized protein 8962 19212 29462
Re07.g00090 Ankyrin repeat-containing protein 8963 19213 29463
Re07.g00100 Uncharacterized protein 8964 19214 29464
Re07.g001 10 Uncharacterized protein 8965 19215 29465
Re07.g00120 Phenylacrylic acid decarboxylase 8966 19216 29466
Re07.g00130 3-dehydroshikimate dehydratase 8967 19217 29467
Quinate utilisation oxidoreductase
Re07.g00140 QutH 8968 19218 29468 32038 33528
Re07.g00150 Uncharacterized protein 8969 19219 29469
Re07.g00160 Uncharacterized protein 8970 19220 29470
Inositol monophosphatase QutG,
Re07.g00170 putative 8971 19221 29471
Re07.g00180 Quinic acid utilization activator 8972 19222 29472
Re07.g00190 Putative uncharacterized protein 8973 19223 29473
Re07.g00200 Putative uncharacterized protein 8974 19224 29474 32039 33529
Re07.g00210 Pc12g09320 protein 8975 19225 29475
Re07.g00220 O-methyltransferase, putative 8976 19226 29476
Re07.g00230 Oxidoreductase 8977 19227 29477
Re07.g00240 MFS general substrate transporter 8978 19228 29478
Related to prenyl cysteine carboxyl
Re07.g00250 methyltransferase 8979 19229 29479 32040 33530
Re07.g00260 Cholinesterase 8980 19230 29480 32041 33531
Re07.g00270 Uncharacterized protein 8981 19231 29481
Re07.g00280 Putative uncharacterized protein 8982 19232 29482
Re07.g00290 Putative uncharacterized protein 8983 19233 29483
Re07.g00300 Uncharacterized protein 8984 19234 29484 32042 33532
Re07.g00310 Pc21 g14580 protein Precursor 8985 19235 29485 32043 33533
Re07.g00320 Uncharacterized protein 8986 19236 29486
Re07.g00330 Putative uncharacterized protein 8987 19237 29487 32044 33534
Re07.g00340 Putative uncharacterized protein 8988 19238 29488 32045 33535
Similarity to hypothetical protein
YER175c -Saccharomyces
Re07.g00350 cerevisiae 8989 19239 29489
Alpha-ketoglutarate-dependent
Re07.g00360 taurine dioxygenase 8990 19240 29490
Re07.g00370 Putative uncharacterized protein 8991 19241 29491
Re07.g00390 Putative uncharacterized protein 8992 19242 29492
Re07.g00400 Uncharacterized protein 8993 19243 29493
Re07.g00410 Uncharacterized protein 8994 19244 29494
Re07.g00420 hypothetical protein 8995 19245 29495
Re07.g00430 hypothetical protein 8996 19246 29496
Re07.g00440 Uncharacterized protein 8997 19247 29497 32046 33536 MFS sugar transporter, putative
Re07.g00450 Fragment 8998 19248 29498
Re07.g00460 MFS sugar transporter, putative 8999 19249 29499
Re07.g00470 hypothetical protein 9000 19250 29500
Re07.g00480 Putative uncharacterized protein 9001 19251 29501
Re07.g00490 Uncharacterized protein 9002 19252 29502
Re07.g00500 Putative uncharacterized protein 9003 19253 29503
Re07.g00510 Uncharacterized protein 9004 19254 29504
Re07.g00520 Uncharacterized protein 9005 19255 29505
Re07.g00530 Putative uncharacterized protein 9006 19256 29506
Re07.g00540 Putative uncharacterized protein 9007 19257 29507
Re07.g00550 Putative uncharacterized protein 9008 19258 29508
Re07.g00560 Predicted protein 9009 19259 29509 32047 33537
Re07.g00570 Putative uncharacterized protein 9010 19260 29510
Re07.g00580 Predicted protein 901 1 19261 2951 1
Re07.g00590 Putative uncharacterized protein 9012 19262 29512
Re07.g00600 Putative uncharacterized protein 9013 19263 29513
Tripeptidyl-peptidase (TppA),
Re07.g00610 putative 9014 19264 29514 32048 33538
Glycoside hydrolase family 79
Re07.g00620 protein 9015 19265 29515 32049 33539
Re07.g00630 NmrA-like family protein 9016 19266 29516
Re07.g00640 hypothetical protein 9017 19267 29517
Re07.g00650 hypothetical protein 9018 19268 29518
Re07.g00660 hypothetical protein 9019 19269 29519
Re07.g00670 Aquaporin 9020 19270 29520
Re07.g00680 GABA permease, putative 9021 19271 29521
Re07.g00690 Uncharacterized protein 9022 19272 29522
Re07.g00700 Uncharacterized protein 9023 19273 29523
Re07.g00710 Fungal specific transcription factor 9024 19274 29524
Re07.g00720 ABC transporter-like protein 9025 19275 29525
Re07.g00730 hypothetical protein 9026 19276 29526 32050 33540
Re07.g00740 Putative uncharacterized protein 9027 19277 29527
Re07.g00750 Putative uncharacterized protein 9028 19278 29528 32051 33541
Re07.g00760 Uncharacterized protein 9029 19279 29529
Re07.g00770 Sugar transporter, putative 9030 19280 29530
Re07.g00780 Putative uncharacterized protein 9031 19281 29531 32052 33542
Re07.g00790 3-phytase B 9032 19282 29532 32053 33543
Re07.g00800 hypothetical protein 9033 19283 29533 32054 33544
Re07.g00810 hypothetical protein 9034 19284 29534 32055 33545
Re07.g00820 Uncharacterized protein 9035 19285 29535
Re07.g00830 Predicted protein 9036 19286 29536
Re07.g00840 Putative uncharacterized protein 9037 19287 29537
Re07.g00850 Nitrilase 9038 19288 29538
Re07.g00860 hypothetical protein 9039 19289 29539
Re07.g00880 Uncharacterized protein 9040 19290 29540 32056 33546
Re07.g00890 hypothetical protein 9041 19291 29541
Cell wall glycosyl hydrolase Dfg5,
Re07.g00900 putative 9042 19292 29542 32057 33547 Re07.g00910 Amidase 9043 19293 29543 32058 33548
Re07.g00920 hypothetical protein 9044 19294 29544
Re07.g00930 hypothetical protein 9045 19295 29545
Re07.g00940 hypothetical protein 9046 19296 29546
Re07.g00950 BZIP transcription factor, putative 9047 19297 29547
Chromatin remodeling complex
Re07.g00960 subunit (Arp5), putative 9048 19298 29548
Re07.g00970 Uncharacterized protein 9049 19299 29549
Re07.g00980 Uncharacterized protein 9050 19300 29550
Re07.g00990 Got1 -like family protein 9051 19301 29551
Re07.g01000 NACHT domain protein 9052 19302 29552 32059 33549
Re07.g01010 Profilin 9053 19303 29553
Re07.g01020 hypothetical protein 9054 19304 29554 32060 33550
Re07.g01030 Putative uncharacterized protein 9055 19305 29555
Re07.g01040 DEAD/DEAH box helicase, putative 9056 19306 29556
Re07.g01050 Uncharacterized protein 9057 19307 29557
Re07.g01060 MGMT family protein 9058 19308 29558
Re07.g01070 Uncharacterized protein 9059 19309 29559
Serine protein kinase Sky1 ,
Re07.g01080 putative 9060 19310 29560
Re07.g01090 hypothetical protein 9061 1931 1 29561
Phosphoric ester hydrolase,
Re07.g01 100 putative 9062 19312 29562
Mitochondrial cytochrome b2,
Re07.g01 1 10 putative 9063 19313 29563
Ras-like GTP-binding protein,
Re07.g01 120 putative 9064 19314 29564
Re07.g01 130 Uncharacterized protein 9065 19315 29565 32061 33551
Re07.g01 140 Uncharacterized protein 9066 19316 29566
Nuclear envelope protein Brr6,
Re07.g01 150 putative 9067 19317 29567
Re07.g01 160 Uncharacterized protein 9068 19318 29568
Acetoacetyl-coenzyme A
Re07.g01 170 synthetase 9069 19319 29569
Putative acetoacetyl-synthase
Re07.g01 180 protein 9070 19320 29570 32062 33552
Alpha.alpha-trehalose-phosphate
synthase subunit, putative
Re07.g01 190 EC=2.4.1.15 9071 19321 29571
Re07.g01200 Amino acid permease 9072 19322 29572
Re07.g01210 Uncharacterized protein Fragment 9073 19323 29573
Putative phthalate transporter
Re07.g01220 protein 9074 19324 29574 32063 33553
DUF1212 domain membrane
Re07.g01230 protein 9075 19325 29575
Re07.g01240 hypothetical protein 9076 19326 29576
6-phosphofructokinase
Re07.g01250 EC=2.7.1.1 1 9077 19327 29577
Re07.g01260 Putative uncharacterized protein 9078 19328 29578 Re07.g01270 Conserved mitochondrial protein 9079 19329 29579
Succinyl-CoA:3-ketoacid- coenzyme A transferase
Re07.g01280 EC=2.8.3.5 9080 19330 29580
Re07.g01290 Putative uncharacterized protein 9081 19331 29581
Re07.g01300 Putative uncharacterized protein 9082 19332 29582
Re07.g01310 Putative uncharacterized protein 9083 19333 29583 32064 33554
Re07.g01320 hypothetical protein 9084 19334 29584
Mediator of RNA polymerase II
Re07.g01330 transcription subunit 17 9085 19335 29585
IMP-specific 5'-nucleotidase 1
Re07.g01340 EC=3.1.3.- 9086 19336 29586
Re07.g01350 Uncharacterized protein 9087 19337 29587
Re07.g01360 Putative uncharacterized protein 9088 19338 29588
Patatin-like serine hydrolase,
Re07.g01370 putative 9089 19339 29589
Re07.g01380 Putative uncharacterized protein 9090 19340 29590
Re07.g01390 Putative uncharacterized protein 9091 19341 29591 32065 33555
Re07.g01400 hypothetical protein 9092 19342 29592
Vesicle-mediated transport protein
Re07.g01410 (Imh1 ), putative 9093 19343 29593
Plasma membrane channel protein
Re07.g01420 (Aqy1 ), putative 9094 19344 29594 32066 33556
Re07.g01430 Na+/K+ ATPase, alpha subunit 9095 19345 29595
Sterol 24-c-methyltransferase,
Re07.g01440 putative 9096 19346 29596
Pre-RNA splicing factor Slt1 1 ,
Re07.g01450 putative 9097 19347 29597
Mitochondrial zinc maintenance
Re07.g01460 protein 1 , mitochondrial Precursor 9098 19348 29598
Ribosome associated DnaJ
Re07.g01470 chaperone Zuotin, putative 9099 19349 29599
Aryl-alcohol dehydrogenase
Re07.g01480 Aad14, putative 9100 19350 29600
Re07.g01490 Uncharacterized protein 9101 19351 29601 32067 33557
Re07.g01500 hypothetical protein 9102 19352 29602 32068 33558
Probable endo-beta-1 ,4-glucanase
Re07.g01520 celB EC=3.2.1.4 Precursor 9103 19353 29603 32069 33559
Re07.g01530 Putative uncharacterized protein 9104 19354 29604
Re07.g01540 Putative uncharacterized protein 9105 19355 29605
Re07.g01550 Uncharacterized protein 9106 19356 29606
Re07.g01560 High affinity methionine permease 9107 19357 29607
Re07.g01570 hypothetical protein 9108 19358 29608
Re07.g01580 Uncharacterized protein 9109 19359 29609 32070 33560
Re07.g01590 hypothetical protein 91 10 19360 29610
Re07.g01600 Uncharacterized protein 91 1 1 19361 2961 1
Serine peptidase, family S28,
Re07.g01610 putative 91 12 19362 29612 32071 33561
Re07.g01620 Chlorohydrolase family protein 91 13 19363 29613 EC=3.5.4.3
Glycine dehydrogenase
Re07.g01630 EC=1.3.1.74 91 14 19364 29614
Re07.g01640 MFS transporter, putative 91 15 19365 29615 32072 33562
Re07.g01650 hypothetical protein 91 16 19366 29616
Re07.g01660 Pc22g04150 protein 91 17 19367 29617
Re07.g01670 Putative uncharacterized protein 91 18 19368 29618 32073 33563
Re07.g01680 C6 zinc finger domain protein 91 19 19369 29619
MFS monocarboxylate transporter,
Re07.g01690 putative 9120 19370 29620
Re07.g01700 Cupin domain protein 9121 19371 29621
Re07.g01710 Putative uncharacterized protein 9122 19372 29622
Aromatic-L-amino-acid
Re07.g01720 decarboxylase 9123 19373 29623
Re07.g01730 Putative uncharacterized protein 9124 19374 29624 32074 33564
Re07.g01750 DNA repair protein Nse1 , putative 9125 19375 29625
FAD dependent oxidoreductase
Re07.g01760 superfamily 9126 19376 29626
Short-chain
Re07.g01770 dehydrogenase/reductase, putative 9127 19377 29627
Re07.g01780 Hexokinase XprF 9128 19378 29628
Chromatin remodeling complex
Re07.g01790 subunit (Arp9), putative 9129 19379 29629
Re07.g01800 hypothetical protein 9130 19380 29630
Re07.g01810 C2H2 finger domain protein 9131 19381 29631
Re07.g01820 Fascidin domain containing protein 9132 19382 29632 32075 33565
Re07.g01830 Uncharacterized protein 9133 19383 29633
Re07.g01840 MFS transporter 9134 19384 29634
Re07.g01850 Similar to An13g01980 9135 19385 29635
Re07.g01860 Uncharacterized protein 9136 19386 29636
Re07.g01870 Putative uncharacterized protein 9137 19387 29637
SNF7 family protein Fti1/Did2,
putative (AFU orthologue
Re07.g01880 AFUA_3G04060) 9138 19388 29638
Re07.g01890 BZIP transcription factor HacA 9139 19389 29639 32076 33566 rRNA processing protein Bystin,
Re07.g01900 putative 9140 19390 29640
Re07.g01910 Putative uncharacterized protein 9141 19391 29641
(S)-2-hydroxy-acid oxidase,
Re07.g01920 putative 9142 19392 29642
Re07.g01930 Uncharacterized protein 9143 19393 29643
Glutamyl-tRNA amidotransferase,
Re07.g01940 A subunit, putative 9144 19394 29644
Mitochondrial enoyl reductase,
Re07.g01950 putative 9145 19395 29645
Re07.g01960 Ser/Thr protein phosphatase family 9146 19396 29646 32077 33567
Pyruvate dehydrogenase E1 beta
Re07.g01970 subunit PdbA, putative 9147 19397 29647 32078 33568
Re07.g01980 Uncharacterized protein 9148 19398 29648 GNAT family acetyltransferase,
Re07.g01990 putative 9149 19399 29649
Re07.g02000 Uncharacterized protein 9150 19400 29650
N2,N2-dimethylguanosine tRNA
Re07.g02010 methyltransferase 9151 19401 29651
Re07.g02020 Uncharacterized protein 9152 19402 29652
Fatty acid synthase alpha subunit
Re07.g02030 FasA 9153 19403 29653
Fatty acid synthase beta subunit,
Re07.g02040 putative EC=2.3.1.38 9154 19404 29654
Re07.g02050 Transcription initiation factor IIF 9155 19405 29655
S-M checkpoint control protein
CID1 and related
Re07.g02060 nucleotidyltransferases 9156 19406 29656
Re07.g02070 Uncharacterized protein 9157 19407 29657
Re07.g02080 Uncharacterized protein 9158 19408 29658
Re07.g02090 Predicted protein 9159 19409 29659
Re07.g02100 Lipase/serine esterase, putative 9160 19410 29660
Re07.g021 10 Putative uncharacterized protein 9161 1941 1 29661
Actin cytoskeleton organization and
Re07.g02120 biogenesis protein, putative 9162 19412 29662
Re07.g02130 SnoRNA binding protein 9163 19413 29663
Re07.g02140 Putative uncharacterized protein 9164 19414 29664
Re07.g02150 DUF652 domain-containing protein 9165 19415 29665 32079 33569
Re07.g02160 Transposase 9166 19416 29666
Re07.g02170 Transposon, putative 9167 19417 29667
Re07.g02180 Putative uncharacterized protein 9168 19418 29668
Re07.g02190 hypothetical protein 9169 19419 29669
Re07.g02200 hypothetical protein 9170 19420 29670
Re07.g02210 hypothetical protein 9171 19421 29671
Re07.g02220 hypothetical protein 9172 19422 29672
Re07.g02230 hypothetical protein 9173 19423 29673
Re07.g02240 Putative uncharacterized protein 9174 19424 29674 32080 33570
Re07.g02250 hypothetical protein 9175 19425 29675 32081 33571
Re07.g02260 Putative uncharacterized protein 9176 19426 29676
Re07.g02270 Putative uncharacterized protein 9177 19427 29677
Gag/polymerase/env polyprotein,
Re07.g02280 putative 9178 19428 29678
C-4 methyl sterol oxidase Erg25,
Re07.g02290 putative 9179 19429 29679
Re07.g02300 Uncharacterized protein 9180 19430 29680
Re07.g02310 Rab GTPase SrgA, putative 9181 19431 29681
Re07.g02320 Predicted protein 9182 19432 29682
Re07.g02330 Putative uncharacterized protein 9183 19433 29683
Transposon-encoded proteins with
Re07.g02340 TYA 9184 19434 29684
Re07.g02350 AAA family ATPase, putative 9185 19435 29685
Inositol kinase kinase (UvsB),
Re07.g02360 putative EC=2.7.1 1.1 9186 19436 29686 tRNA specific adenosine
Re07.g02370 deaminase 9187 19437 29687
NADH-ubiquinone oxidoreductase
Re07.g02380 21 kDa subunit, putative 9188 19438 29688
Re07.g02390 Pc13g05650 protein 9189 19439 29689
FGGY-family carbohydrate kinase,
Re07.g02400 putative 9190 19440 29690
Re07.g02410 Putative uncharacterized protein 9191 19441 29691 32082 33572
Re07.g02420 Uncharacterized protein 9192 19442 29692
Protein tyrosine phosphatase
Re07.g02430 (Pyp1 ), putative 9193 19443 29693
Cytochrome c oxidase assembly
protein cox16, mitochondrial
Re07.g02440 Precursor 9194 19444 29694
Re07.g02450 Putative uncharacterized protein 9195 19445 29695 32083 33573
Re07.g02460 Riboflavin-specific deaminase 9196 19446 29696
Calcium permease family
Re07.g02470 membrane transporter 9197 19447 29697
Proteasome regulatory particle
Re07.g02480 subunit Rpt6, putative 9198 19448 29698
Re07.g02490 Putative uncharacterized protein 9199 19449 29699
Re07.g02500 Putative uncharacterized protein 9200 19450 29700
Ubiquitin fusion degradation protein
Re07.g02510 (Ufd1 ), putative 9201 19451 29701
Rab GTPase interacting factor,
Re07.g02520 Golgi family membrane protein 9202 19452 29702
Outer membrane protein, OMP85
Re07.g02530 family 9203 19453 29703
Ubiquitin-conjugating enzyme
Re07.g02540 Ubc6, putative 9204 19454 29704
Re07.g02550 Uncharacterized protein 9205 19455 29705
Re07.g02560 Cytochrome C1 heme lyase 9206 19456 29706
Re07.g02570 ABC1 family protein 9207 19457 29707
Re07.g02580 Uncharacterized protein 9208 19458 29708
Re07.g02590 Putative uncharacterized protein 9209 19459 29709
Re07.g02600 Flocculation suppression protein 9210 19460 29710
Re07.g02610 Predicted protein 921 1 19461 2971 1
Succinyl-CoA synthetase beta
Re07.g02620 subunit, putative EC=6.2.1.5 9212 19462 29712
Short chain
Re07.g02630 dehydrogenase/reductase, putative 9213 19463 29713
C4-dicarboxylate/malic acid
Re07.g02640 transporter 9214 19464 29714
Xanthine-guanine phosphoribosyl
Re07.g02650 transferase Xpt1 , putative 9215 19465 29715
Re07.g02660 Putative uncharacterized protein 9216 19466 29716
Re07.g02670 Uncharacterized protein 9217 19467 29717
Re07.g02680 Uncharacterized protein 9218 19468 29718
Re07.g02690 Putative uncharacterized protein 9219 19469 29719
Re07.g02700 Putative uncharacterized protein 9220 19470 29720 Conserved leucine-rich repeat
Re07.g02710 protein 9221 19471 29721
Re07.g02720 Uncharacterized protein 9222 19472 29722 32084 33574
Re07.g02730 Actin family protein 9223 19473 29723
Re07.g02740 Putative uncharacterized protein 9224 19474 29724
Re07.g02750 IBR domain-containing protein 9225 19475 29725
Re07.g02760 Uncharacterized protein 9226 19476 29726
3-hydroxybutyryl-CoA
Re07.g02770 dehydrogenase, putative 9227 19477 29727 32085 33575
Re07.g02780 Mating-type switching protein swil 9228 19478 29728
Re07.g02790 Uncharacterized protein 9229 19479 29729
Re07.g02800 Putative uncharacterized protein 9230 19480 29730
Re07.g02810 Uncharacterized protein 9231 19481 29731
Re07.g02820 Uncharacterized protein 9232 19482 29732 32086 33576
Re07.g02830 Uncharacterized protein 9233 19483 29733
MFS transporter, SP family,
Re07.g02840 sugar:H+ symporter 9234 19484 29734
Re07.g02850 Glucanase 9235 19485 29735
Re07.g02860 Predicted protein 9236 19486 29736
Re07.g02870 Putative uncharacterized protein 9237 19487 29737
Re07.g02880 Predicted dehydrogenase 9238 19488 29738
TFIIH and nucleotide excision
repair factor 3 complexes subunit
Re07.g02890 (Tfb2), putative 9239 19489 29739
Re07.g02900 Putative uncharacterized protein 9240 19490 29740
Re07.g02910 DEAD helicase superfamily protein 9241 19491 29741
THO complex subunit Tho1 ,
Re07.g02920 putative 9242 19492 29742
Homeobox transcription factor,
Re07.g02930 putative 9243 19493 29743
Copper resistance protein Crd2,
Re07.g02940 putative 9244 19494 29744
AP-2 adaptor complex subunit
Re07.g02950 alpha, putative 9245 19495 29745
Alanine racemase family protein,
Re07.g02960 putative 9246 19496 29746
Re07.g02970 hypothetical protein 9247 19497 29747
Re07.g02980 hypothetical protein 9248 19498 29748
Re07.g02990 Uncharacterized protein 9249 19499 29749
Re07.g03000 AN1 zinc finger protein 9250 19500 29750
Re07.g03010 Thymidylate synthase EC=2.1.1.45 9251 19501 29751
Queuine tRNA-ribosyltransferase
Re07.g03020 EC=2.4.2.29 9252 19502 29752
Re07.g03030 Uncharacterized protein 9253 19503 29753
Re07.g03040 hypothetical protein 9254 19504 29754
Re07.g03050 Putative uncharacterized protein 9255 19505 29755
Re07.g03060 hypothetical protein 9256 19506 29756
Re07.g03070 Uncharacterized protein 9257 19507 29757
Re07.g03080 Uncharacterized protein 9258 19508 29758 32087 33577 Myo-inositol-1 (Or 4)-
Re07.g03090 monophosphatase 9259 19509 29759
Re07.g03100 Putative uncharacterized protein 9260 19510 29760 32088 33578
Re07.g031 10 Chitin synthase B EC=2.4.1.16 9261 1951 1 29761
Re07.g03120 Integral membrane protein 9262 19512 29762 32089 33579
Re07.g03130 LysM domain-containing protein 9263 19513 29763
Nuclear pore complex protein
Re07.g03140 (Son A), putative 9264 19514 29764
Re07.g03150 TAM domain methyltransferase 9265 19515 29765
Re07.g03160 Uncharacterized protein 9266 19516 29766
Re07.g03170 Uncharacterized protein 9267 19517 29767
Re07.g03180 hypothetical protein 9268 19518 29768
Re07.g03190 hypothetical protein 9269 19519 29769
Mitochondrial ATPase (Afg1 ),
Re07.g03200 putative 9270 19520 29770
Re07.g03210 Uncharacterized protein 9271 19521 29771
Re07.g03220 ABC transporter 9272 19522 29772
Re07.g03230 C6 transcription factor, putative 9273 19523 29773 32090 33580
Similarity to EST SEQ ID NO:4295
Re07.g03240 from patent WO200056762-A2 9274 19524 29774
Re07.g03250 hypothetical protein 9275 19525 29775
Gag/polymerase/env polyprotein,
Re07.g03260 putative 9276 19526 29776
Protein kinase activator Bem1 ,
Re07.g03270 putative 9277 19527 29777
Re07.g03280 SAC3/GANP domain protein 9278 19528 29778
Vacuolar protein sorting protein
Re07.g03290 (Vps36), putative 9279 19529 29779
Conserved serine-threonine rich
Re07.g03300 protein 9280 19530 29780 32091 33581
Re07.g03310 Uncharacterized protein 9281 19531 29781
Re07.g03320 hypothetical protein 9282 19532 29782
Re07.g03330 Uncharacterized protein Fragment 9283 19533 29783 32092 33582
Re07.g03340 Ammonium transporter, putative 9284 19534 29784
Re07.g03350 Putative uncharacterized protein 9285 19535 29785
Re07.g03360 RING finger protein (Zin), putative 9286 19536 29786
Re07.g03370 Cystathionine beta-lyase MetG 9287 19537 29787
Fungal specific transcription factor
Re07.g03380 domain protein 9288 19538 29788
Re07.g03390 hypothetical protein 9289 19539 29789
GPI-anchor biosynthetic protein
Re07.g03400 (Mcd4), putative 9290 19540 29790 32093 33583
Chromosome segregation protein
Re07.g03410 (Pcs1 ), putative 9291 19541 29791
Membrane-spanning ATPase,
Re07.g03420 putative 9292 19542 29792 32094 33584
Re07.g03430 LysM domain protein, putative 9293 19543 29793
Re07.g03440 Uncharacterized protein 9294 19544 29794 32095 33585
Re07.g03450 Peptidyl-prolyl cis-trans isomerase 9295 19545 29795 Re07.g03460 Histidinol-phosphatase 9296 19546 29796
Re07.g03470 Pc13g06130 protein 9297 19547 29797 32096 33586
Re07.g03480 Putative uncharacterized protein 9298 19548 29798
Ribosome biogenesis protein
Re07.g03490 (Rrs1 ), putative 9299 19549 29799
Mitochondrial ribosomal protein
Re07.g03500 DAP3, putative 9300 19550 29800 32097 33587
Re07.g03510 Uncharacterized protein 9301 19551 29801
Re07.g03520 Ferric-chelate reductase, putative 9302 19552 29802
Re07.g03530 Cysteine synthase 9303 19553 29803 32098 33588
Putative mfs drug transporter
Re07.g03540 protein 9304 19554 29804
Re07.g03550 hypothetical protein 9305 19555 29805
Re07.g03560 hypothetical protein 9306 19556 29806
Re07.g03570 hypothetical protein 9307 19557 29807 32099 33589
Re07.g03580 hypothetical protein 9308 19558 29808
Transcriptional regulator
Re07.g03590 PacG/VIB-1 9309 19559 29809
Re07.g03600 hypothetical protein 9310 19560 29810
Re07.g03610 Beta-N-acetylglucosaminidase 931 1 19561 2981 1
Glucosamine-6-phosphate
Re07.g03620 isomerase 9312 19562 29812
Re07.g03630 Choline oxidase (Cod A), putative 9313 19563 29813
Re07.g03640 Uncharacterized protein 9314 19564 29814
N-acetylglucosamine-6-phosphate
Re07.g03650 deacetylase 9315 19565 29815
Re07.g03660 DUF895 domain membrane protein 9316 19566 29816
Re07.g03670 Pol Fragment 9317 19567 29817
Re07.g03680 Putative uncharacterized protein 9318 19568 29818
Re07.g03690 Galactoside O-acetyltransferase 9319 19569 29819
Re07.g03700 Uncharacterized protein 9320 19570 29820 32100 33590
Re07.g03710 Uncharacterized protein 9321 19571 29821
Re07.g03720 hypothetical protein 9322 19572 29822
C6 transcription factor (Ctfl B),
Re07.g03730 putative 9323 19573 29823
Re07.g03740 Pc13g08550 protein 9324 19574 29824
Re07.g03750 Putative uncharacterized protein 9325 19575 29825
Re07.g03760 Sugar transport protein 9326 19576 29826 32101 33591
Re07.g03770 Predicted protein 9327 19577 29827
Re07.g03780 Pc24g00420 protein 9328 19578 29828
Re07.g03790 Putative uncharacterized protein 9329 19579 29829 32102 33592
Re07.g03800 Putative uncharacterized protein 9330 19580 29830
Re07.g03810 Uncharacterized protein 9331 19581 29831
Re07.g03820 Uncharacterized protein 9332 19582 29832 32103 33593
Re07.g03830 Uncharacterized protein 9333 19583 29833 32104 33594
Re07.g03840 Uncharacterized protein 9334 19584 29834
Sodium/calcium transporter,
Re07.g03850 putative 9335 19585 29835
Re07.g03860 Uncharacterized protein 9336 19586 29836 32105 33595 Re07.g03870 Putative uncharacterized protein 9337 19587 29837
Re07.g03880 MFS transporter 9338 19588 29838 32106 33596
Re07.g03890 Putative uncharacterized protein 9339 19589 29839
Re07.g03900 Protein sip5 9340 19590 29840
Re07.g03910 Uncharacterized protein 9341 19591 29841
Re07.g03930 Uncharacterized protein 9342 19592 29842
Actin cytoskeleton protein (VIP1 ),
Re07.g03940 putative 9343 19593 29843
Re07.g03950 hypothetical protein 9344 19594 29844
Nonsense-mediated mRNA decay
Re07.g03960 protein (Nmd5), putative 9345 19595 29845
Re07.g03970 Putative uncharacterized protein 9346 19596 29846
Re07.g03980 Putative uncharacterized protein 9347 19597 29847
Mitochondrial Hsp70 chaperone
Re07.g03990 (Ssc70), putative 9348 19598 29848
Putative uncharacterized protein
Re07.g04000 An16g05120 9349 19599 29849
Re07.g04010 Putative uncharacterized protein 9350 19600 29850
AMP-binding enzyme (Fum16),
Re07.g04020 putative 9351 19601 29851
Re07.g04030 Putative uncharacterized protein 9352 19602 29852 32107 33597
Re07.g04040 hypothetical protein 9353 19603 29853
Re07.g04050 Putative uncharacterized protein 9354 19604 29854
Re07.g04060 hypothetical protein 9355 19605 29855
Re07.g04070 hypothetical protein 9356 19606 29856
Eukaryotic translation initiation
Re07.g04080 factor 3 subunit G 9357 19607 29857
Re07.g04090 Purine-cytosine permease 9358 19608 29858
40S ribosomal protein S29,
Re07.g04100 putative 9359 19609 29859
Oxidoreductase, 2-nitropropane
Re07.g041 10 dioxygenase family, putative 9360 19610 29860
Re07.g04120 Putative uncharacterized protein 9361 1961 1 29861
Re07.g04130 Putative uncharacterized protein 9362 19612 29862
Re07.g04140 Uncharacterized protein 9363 19613 29863
Re07.g04150 Putative uncharacterized protein 9364 19614 29864
Re07.g04160 Putative uncharacterized protein 9365 19615 29865
Re07.g04170 Putative uncharacterized protein 9366 19616 29866
Mandelate racemase/muconate
Re07.g04180 lactonizing enzyme family protein 9367 19617 29867
Re07.g04190 Putative uncharacterized protein 9368 19618 29868
Re07.g04200 Predicted protein 9369 19619 29869
Re07.g04210 hypothetical protein 9370 19620 29870
Re07.g04220 Glucose-6-phosphate isomerase 9371 19621 29871
Re07.g04230 Putative uncharacterized protein 9372 19622 29872 32108 33598
Re07.g04240 Uncharacterized protein 9373 19623 29873
Re07.g04250 Putative uncharacterized protein 9374 19624 29874 32109 33599
Re07.g04260 Putative uncharacterized protein 9375 19625 29875
Re07.g04270 Uncharacterized protein 9376 19626 29876 Re07.g04280 Uncharacterized protein 9377 19627 29877
Superoxide dismutase copper
Re07.g04290 chaperone Lys7, putative 9378 19628 29878
Re07.g04300 PB1 domain protein, putative 9379 19629 29879
Function: Tto1 can transpose
autonomously through reverse
transcription EC=2.7.7.49
EC=2.7.7.49 EC=2.7.7.49
Re07.g04310 EC=2.7.7.49 9380 19630 29880
Re07.g04320 SNARE protein (Ufe1), putative 9381 19631 29881
Re07.g04330 Aspartate transaminase 9382 19632 29882
RING finger domain protein,
Re07.g04340 putative 9383 19633 29883 321 10 33600
Re07.g04350 Putative uncharacterized protein 9384 19634 29884
Re07.g04360 Putative uncharacterized protein 9385 19635 29885
Phytanoyl-CoA dioxygenase family
Re07.g04370 protein 9386 19636 29886
Re07.g04380 Serine/threonine protein kinase 9387 19637 29887
Re07.g04390 Pc22g 19390 protein 9388 19638 29888 321 1 1 33601
Re07.g04400 Uncharacterized protein 9389 19639 29889
Re07.g04410 Biotin apo-protein ligase, putative 9390 19640 29890
Re07.g04420 Uncharacterized protein 9391 19641 29891
Re07.g04430 HVA22 domain membrane protein 9392 19642 29892 321 12 33602
Eukaryotic translation initiation
Re07.g04440 factor subunit elF-4F, putative 9393 19643 29893
Universal stress protein family
Re07.g04450 domain protein 9394 19644 29894
Re07.g04460 Putative uncharacterized protein 9395 19645 29895
Re07.g04470 hypothetical protein 9396 19646 29896 321 13 33603
Re07.g04480 Flavohemoprotein 9397 19647 29897
Re07.g04490 hypothetical protein 9398 19648 29898
Re07.g04500 Uncharacterized protein 9399 19649 29899
Re07.g04510 Uncharacterized protein 9400 19650 29900
Re07.g04520 Uncharacterized protein 9401 19651 29901 321 14 33604
Re07.g04530 Putative uncharacterized protein 9402 19652 29902 321 15 33605
DNA repair protein Rhp26/Rad26,
Re07.g04540 putative 9403 19653 29903
Re07.g04550 Protein kinase Yak1 , putative 9404 19654 29904
Eukaryotic translation initiation
Re07.g04560 factor 3 subunit C 9405 19655 29905
Re07.g04570 hypothetical protein 9406 19656 29906
ELL complex subunit Eap30,
Re07.g04580 putative 9407 19657 29907
Re07.g04590 60S ribosomal protein L7, putative 9408 19658 29908
Re07.g04600 Uncharacterized protein 9409 19659 29909
Peroxisomal multifunctional beta- oxidation protein (MFP), putative
Re07.g04610 EC=4.2.1.107 9410 19660 29910
Re07.g04620 Uncharacterized protein 941 1 19661 2991 1 Re07.g04630 Rab geranylgeranyl transferase 9412 19662 29912
Re07.g04640 Uncharacterized protein 9413 19663 29913
Re07.g04650 Putative uncharacterized protein 9414 19664 29914
DNA mismatch repair protein
Re07.g04660 MSH3 9415 19665 29915
Re07.g04670 Complex: RPS28B 9416 19666 29916
DNA mismatch repair protein Msh3
Re07.g04680 Fragment 9417 19667 29917
Re07.g04690 Short-chain dehydrogenase 9418 19668 29918
Alcohol dehydrogenase, zinc-
Re07.g04700 containing 9419 19669 29919
Multidrug resistance-associated
Re07.g04710 protein, putative 9420 19670 29920 321 16 33606
Re07.g04720 Uncharacterized protein 9421 19671 29921
Re07.g04730 Uncharacterized protein 9422 19672 29922
Re07.g04740 Putative uncharacterized protein 9423 19673 29923
Re07.g04750 Uncharacterized protein 9424 19674 29924
Re07.g04760 hypothetical protein 9425 19675 29925
O-methylsterigmatocystin
Re07.g04770 oxidoreductase, putative 9426 19676 29926
Re07.g04780 Uncharacterized protein 9427 19677 29927
Re07.g04790 Pc12g02140 protein 9428 19678 29928
Re07.g04800 Putative uncharacterized protein 9429 19679 29929
Re07.g04810 Uncharacterized protein 9430 19680 29930 321 17 33607
Dimethylaniline monooxygenase
Re07.g04820 (N-oxide forming) 9431 19681 29931
Re07.g04830 Mannose-binding lectin 9432 19682 29932
Re07.g04840 Uncharacterized protein 9433 19683 29933
Re07.g04850 Pfs domain-containing protein 9434 19684 29934
Re07.g04860 Putative uncharacterized protein 9435 19685 29935
Re07.g04870 Uncharacterized protein 9436 19686 29936 321 18 33608
TfdA family oxidoreductase,
Re07.g04880 putative 9437 19687 29937
Re07.g04890 Uncharacterized protein Fragment 9438 19688 29938
Re07.g04900 Putative uncharacterized protein 9439 19689 29939
Re07.g04910 Predicted protein 9440 19690 29940
Re07.g04920 Uncharacterized protein 9441 19691 29941
Putative short-chain
Re07.g04930 dehydrogenase reductase protein 9442 19692 29942
Related to 0- methylsterigmatocystin
Re07.g04940 oxidoreductase 9443 19693 29943 321 19 33609
Short chain
dehydrogenase/reductase family
Re07.g04950 oxidoreductase, putative 9444 19694 29944
Re07.g04960 Uncharacterized protein 9445 19695 29945
Re07.g04970 Uncharacterized protein 9446 19696 29946
Gag/polymerase/env polyprotein,
Re07.g04980 putative 9447 19697 29947 Re07.g04990 Predicted protein 9448 19698 29948
Re07.g05000 Putative uncharacterized protein 9449 19699 29949
Re07.g05010 hypothetical protein 9450 19700 29950
Re07.g05020 TBC domain protein, putative 9451 19701 29951
Re07.g05030 Beta-glucuronidase 9452 19702 29952 32120 33610
Re07.g05040 Uncharacterized protein 9453 19703 29953
Re07.g05050 Predicted protein 9454 19704 29954
Re07.g05060 Putative uncharacterized protein 9455 19705 29955
Putative uncharacterized protein
Re07.g05070 Fragment 9456 19706 29956
Re07.g05080 Putative uncharacterized protein 9457 19707 29957
Re07.g05090 Putative uncharacterized protein 9458 19708 29958
Re07.g05100 hypothetical protein 9459 19709 29959
Re07.g051 10 C6 transcription factor, putative 9460 19710 29960
Re07.g05130 Uncharacterized protein 9461 1971 1 29961
Hydroxybutyrate dehydrogenase,
Re07.g05140 putative 9462 19712 29962
NF-X1 finger transcription factor,
Re07.g05150 putative 9463 19713 29963
Re07.g05160 hypothetical protein 9464 19714 29964
Re07.g05170 Uncharacterized protein 9465 19715 29965
Re07.g05180 Uncharacterized protein 9466 19716 29966
Re07.g05190 Vacuolar calcium ion transporter 9467 19717 29967
Ca2+/H+ antiporter VCX1 and
Re07.g05200 related proteins 9468 19718 29968
Re07.g05210 Vacuolar calcium ion transporter 9469 19719 29969
Re07.g05220 Endoglucanase, putative 9470 19720 29970 32121 3361 1
Re07.g05230 Putative uncharacterized protein 9471 19721 29971
Re07.g05240 RTA1 domain protein, putative 9472 19722 29972
Re07.g05250 Uncharacterized protein 9473 19723 29973
Re07.g05260 Putative uncharacterized protein 9474 19724 29974
Re07.g05270 Sulfhydryl oxidase EC=1.8.3.2 9475 19725 29975 32122 33612
Re07.g05280 Putative uncharacterized protein 9476 19726 29976 32123 33613
F1 FO ATP synthase assembly
Re07.g05290 protein Atp 1 1 , putative 9477 19727 29977
Re07.g05300 BEM46 family protein 9478 19728 29978
Proteasome subunit beta type
Re07.g05310 EC=3.4.25.1 9479 19729 29979
Cyclin-dependent protein kinase
Re07.g05320 complex component, putative 9480 19730 29980
Re07.g05330 hypothetical protein 9481 19731 29981
Re07.g05340 Putative uncharacterized protein 9482 19732 29982
Re07.g05350 DUF453 domain-containing protein 9483 19733 29983
Re07.g05360 hypothetical protein 9484 19734 29984
Re07.g05370 Putative uncharacterized protein 9485 19735 29985
Re07.g05380 hypothetical protein 9486 19736 29986
Re07.g05390 Ulp1 protease family protein 9487 19737 29987
Rho guanyl nucleotide exchange
Re07.g05400 factor, putative 9488 19738 29988 Telomerase reverse transcriptase,
Re07.g05410 putative EC=2.7.7.49 9489 19739 29989
Cycloheximide resistance protein,
Re07.g05420 putative 9490 19740 29990
Re07.g05430 Monoxygenase, putative 9491 19741 29991 32124 33614
Re07.g05440 Cytochrome P450, putative 9492 19742 29992 32125 33615
Glucose-methanol-choline
Re07.g05450 oxidoreductase 9493 19743 29993
Re07.g05460 Uncharacterized protein 9494 19744 29994
Re07.g05470 Putative uncharacterized protein 9495 19745 29995
Re07.g05480 Uncharacterized protein 9496 19746 29996
Re07.g05490 MFS general substrate transporter 9497 19747 29997
Re07.g05500 hypothetical protein 9498 19748 29998
Re07.g05510 Uncharacterized protein 9499 19749 29999
Re07.g05520 Oxidoreductase, putative 9500 19750 30000
Re07.g05530 Uncharacterized protein 9501 19751 30001 32126 33616
Re07.g05540 Glycosyl hydrolase, putative 9502 19752 30002
Re07.g05550 Uncharacterized protein 9503 19753 30003
Re07.g05560 Uncharacterized protein 9504 19754 30004
Re07.g05570 Uncharacterized protein 9505 19755 30005
Re07.g05580 Reverse transcriptase, putative 9506 19756 30006
Re07.g05590 Uncharacterized protein 9507 19757 30007
Re07.g05600 Putative uncharacterized protein 9508 19758 30008
Re07.g05610 Uncharacterized protein 9509 19759 30009
Re07.g05620 Uncharacterized protein 9510 19760 30010 32127 33617
Re07.g05630 Uncharacterized protein 951 1 19761 3001 1
Re07.g05640 Uncharacterized protein 9512 19762 30012
Re07.g05650 Uncharacterized protein 9513 19763 30013
Re07.g05660 hypothetical protein 9514 19764 30014 32128 33618
ATP synthase subunit ATP9,
Re07.g05670 putative 9515 19765 30015 32129 33619
Beta-1 ,6 glucan synthetase (Kre6),
Re07.g05680 putative 9516 19766 30016
Re07.g05690 Putative uncharacterized protein 9517 19767 30017 32130 33620
Re07.g05700 Pyruvate dehydrogenase kinase 9518 19768 30018
Re07.g05710 Uncharacterized protein 9519 19769 30019
Re07.g05720 Putative uncharacterized protein 9520 19770 30020
Re07.g05730 hypothetical protein 9521 19771 30021
Re07.g05740 MFS sugar transporter, putative 9522 19772 30022
Phosphoglycerate mutase family
Re07.g05750 protein 9523 19773 30023
Re07.g05760 Ribonucleoprotein, putative 9524 19774 30024
Re07.g05770 Fructose-2,6-bisphosphatase 9525 19775 30025
Vacuolar morphogenesis protein
Re07.g05780 AvaB, putative 9526 19776 30026
Re07.g05790 Putative uncharacterized protein 9527 19777 30027
Re07.g05800 Uncharacterized protein 9528 19778 30028
Re07.g05810 Putative uncharacterized protein 9529 19779 30029
Re07.g05820 Putative uncharacterized protein 9530 19780 30030 Malate dehydrogenase
Re07.g05830 EC=1.1.1.37 9531 19781 30031
Re07.g05840 Protein transport protein BOS1 9532 19782 30032
Probable alpha-galactosidase D
Re07.g05850 EC=3.2.1.22 Precursor 9533 19783 30033 32131 33621
Pyruvate dehydrogenase complex,
Re07.g05860 dihydrolipoamide acetyltransferase 9534 19784 30034
Guanyl-nucleotide exchange factor
Re07.g05870 (Sec7), putative 9535 19785 30035
Re07.g05880 Siroheme synthase Met8, putative 9536 19786 30036
Ribose phosphate
Re07.g05890 diphosphokinase Prs1 , putative 9537 19787 30037 32132 33622
Re07.g05900 Uncharacterized protein 9538 19788 30038
Re07.g05910 Uncharacterized protein 9539 19789 30039
Re07.g05920 Uncharacterized protein 9540 19790 30040
Re07.g05930 Uncharacterized protein 9541 19791 30041
Re07.g05940 hypothetical protein 9542 19792 30042
Re07.g05950 Uncharacterized protein 9543 19793 30043
Translation elongation factor eEF-
Re07.g05960 3, putative 9544 19794 30044
Re07.g05970 Putative uncharacterized protein 9545 19795 30045 32133 33623
Re07.g05980 Putative uncharacterized protein 9546 19796 30046
Putative copper-translocating p-
Re07.g05990 type atpase protein 9547 19797 30047
Re07.g06000 Putative uncharacterized protein 9548 19798 30048 32134 33624
Re07.g06010 hypothetical protein 9549 19799 30049
Re07.g06020 Putative uncharacterized protein 9550 19800 30050
Re07.g06030 Glucanase, putative 9551 19801 30051
APSES transcription factor (MbpA),
Re07.g06040 putative 9552 19802 30052
Re07.g06050 Title: questionable ORF 9553 19803 30053
Re07.g06060 Putative uncharacterized protein 9554 19804 30054
Re07.g06070 Sugar transporter family protein 9555 19805 30055
Re07.g06080 hypothetical protein 9556 19806 30056
GPI maturation protein (Bst1 ),
Re07.g06090 putative 9557 19807 30057
Re07.g06100 Uncharacterized protein 9558 19808 30058 32135 33625
Re07.g061 10 hypothetical protein 9559 19809 30059
Re07.g06120 hypothetical protein 9560 19810 30060
Re07.g06130 Uncharacterized protein 9561 1981 1 30061 32136 33626
Re07.g06140 Pc13g02260 protein 9562 19812 30062
Re07.g06150 Uncharacterized protein 9563 19813 30063
DEAD/DEAH box helicase, putative
Re07.g06160 (AFU.orthologue AFUA_7G05530) 9564 19814 30064 32137 33627
Re07.g06170 Uncharacterized protein 9565 19815 30065
RSC complex subunit (RSC8),
Re07.g06180 putative 9566 19816 30066
Chromosome transmission fidelity
Re07.g06190 protein 18 9567 19817 30067 Re07.g06200 hypothetical protein 9568 19818 30068
Electron transfer flavoprotein alpha
Re07.g06210 subunit, putative 9569 19819 30069
Re07.g06220 Putative uncharacterized protein 9570 19820 30070
NAD-binding Rossmann fold
Re07.g06230 oxidoreductase family protein 9571 19821 30071
Re07.g06240 hypothetical protein 9572 19822 30072
Secreted beta-glucosidase sunl
Re07.g06250 EC=3.2.1.- Precursor 9573 19823 30073 32138 33628
Re07.g06270 hypothetical protein 9574 19824 30074
Re07.g06280 Transcription factor Tos4, putative 9575 19825 30075
Re07.g06290 Snrnp and snornp protein 9576 19826 30076
Re07.g06300 Uncharacterized protein 9577 19827 30077
Nonsense-mediated mRNA decay
Re07.g06310 factor (Upf2), putative 9578 19828 30078
Intermembrane space import and
Re07.g06320 assembly protein 40 9579 19829 30079
Thiamine pyrophosphokinase,
Re07.g06330 putative 9580 19830 30080
Re07.g06340 Putative uncharacterized protein 9581 19831 30081
Re07.g06350 Mitochondrial carrier protein 9582 19832 30082
Re07.g06360 Putative uncharacterized protein 9583 19833 30083
Re07.g06370 Septin AspB 9584 19834 30084
Mitochondrial carrier protein,
Re07.g06380 putative 9585 19835 30085
Re07.g06390 C6 zinc finger domain protein 9586 19836 30086
Re07.g06400 Histone H4.2 9587 19837 30087
Protein phosphatase regulatory
Re07.g06410 subunit Gad , putative 9588 19838 30088
Re07.g06420 Predicted protein 9589 19839 30089
Re07.g06430 Putative uncharacterized protein 9590 19840 30090
Re07.g06440 hypothetical protein 9591 19841 30091
Re07.g06450 SH3 domain protein 9592 19842 30092
Re07.g06460 Annexin 9593 19843 30093
Re07.g06470 EBP domain protein, putative 9594 19844 30094
Re07.g06480 Putative uncharacterized protein 9595 19845 30095
Re07.g06490 hypothetical protein 9596 19846 30096
Re07.g06500 Putative uncharacterized protein 9597 19847 30097
Re07.g06510 Uncharacterized protein 9598 19848 30098
Re07.g06520 Putative uncharacterized protein 9599 19849 30099
Re07.g06530 Similar to An02g05020 9600 19850 30100
54S ribosomal protein L31 ,
Re07.g06540 mitochondrial, putative 9601 19851 30101
Re07.g06550 Tafazzin 9602 19852 30102
ATP-dependent RNA helicase
Re07.g06560 dbp9 EC=3.6.4.13 9603 19853 30103
Re07.g06570 Putative uncharacterized protein 9604 19854 30104
Re07.g06580 Putative uncharacterized protein 9605 19855 30105
Re07.g06590 Uncharacterized protein 9606 19856 30106 Re07.g06600 hypothetical protein 9607 19857 30107
Re07.g06610 Putative uncharacterized protein 9608 19858 30108
Re07.g06620 Uncharacterized protein 9609 19859 30109
Serine/threonine-protein kinase
Re07.g06630 chk2, putative 9610 19860 301 10
Re07.g06640 Putative het-s domain protein 961 1 19861 301 1 1 32139 33629
Re07.g06650 NRPS-like enzyme, putative 9612 19862 301 12
Re07.g06660 Uncharacterized protein 9613 19863 301 13
Glycoside hydrolase family 3
Re07.g06670 protein 9614 19864 301 14
Re07.g06680 Uncharacterized protein 9615 19865 301 15
Putative uncharacterized protein
Re07.g06690 Fragment 9616 19866 301 16
Re07.g06700 Arginyl-tRNA synthetase 9617 19867 301 17
Re07.g06710 Putative uncharacterized protein 9618 19868 301 18
Re07.g06720 Uncharacterized protein 9619 19869 301 19
Re07.g06730 Putative uncharacterized protein 9620 19870 30120
Chromosome segregation protein
Re07.g06740 SudA, putative 9621 19871 30121
Serine/threonine-protein kinase
Re07.g06750 RI01 9622 19872 30122
Re07.g06760 Uncharacterized protein 9623 19873 30123
Probable E3 ubiquitin ligase
Re07.g06770 complex SCF subunit sconB 9624 19874 30124
Probable arabinan endo-1 ,5-alpha-
L-arabinosidase B EC=3.2.1.99
Re07.g06780 Precursor 9625 19875 30125 32140 33630
Re07.g06790 hypothetical protein 9626 19876 30126
Ubiquitin carboxyl-terminal
Re07.g06800 hydrolase EC=3.4.19.12 9627 19877 30127
Re07.g06810 Autophagy protein Atg20, putative 9628 19878 30128
Re07.g06820 hypothetical protein 9629 19879 30129 32141 33631
Re07.g06830 HEAT repeat protein 9630 19880 30130
Mitochondrial import inner
membrane translocase subunit
Re07.g06840 TIM23, putative 9631 19881 30131
Re07.g06850 Putative uncharacterized protein 9632 19882 30132
Re07.g06860 Uncharacterized protein 9633 19883 30133
Dihydroxy acid dehydratase Ilv3,
Re07.g06870 putative EC=4.2.1.9 9634 19884 30134
Re07.g06880 hypothetical protein 9635 19885 30135 32142 33632
Re07.g06890 Uncharacterized protein 9636 19886 30136
Re07.g06900 Uncharacterized protein 9637 19887 30137
Re07.g06910 Putative uncharacterized protein 9638 19888 30138
Re07.g06920 Uncharacterized protein 9639 19889 30139
Re07.g06930 Putative uncharacterized protein 9640 19890 30140
Re07.g06940 hypothetical protein 9641 19891 30141 32143 33633
Re07.g06950 Putative uncharacterized protein 9642 19892 30142
Re07.g06960 hypothetical protein 9643 19893 30143 32144 33634 Re07.g06970 Uncharacterized protein Fragment 9644 19894 30144 32145 33635
Re07.g06980 Putative uncharacterized protein 9645 19895 30145
Re07.g06990 Conidiation protein Con-6, putative 9646 19896 30146
Re07.g07000 Predicted protein 9647 19897 30147
Efflux pump antibiotic resistance
Re07.g07010 protein 9648 19898 30148
Re07.g07020 Putative uncharacterized protein 9649 19899 30149
Putative panthothenate
kinase/uridine kinase-related
Re07.g07030 protein 9650 19900 30150
Re07.g07040 Putative uncharacterized protein 9651 19901 30151
Re07.g07050 Putative uncharacterized protein 9652 19902 30152 32146 33636
Re07.g07060 Uncharacterized protein 9653 19903 30153
Kinesin family protein (KlpA),
Re07.g07070 putative 9654 19904 30154
Re07.g07080 Actin-binding protein, putative 9655 19905 30155
Re07.g07090 Alcohol dehydrogenase, putative 9656 19906 30156
Re07.g07100 Putative uncharacterized protein 9657 19907 30157
Re07.g071 10 Putative uncharacterized protein 9658 19908 30158
Re07.g07120 hypothetical protein 9659 19909 30159 32147 33637
Re07.g07130 hypothetical protein 9660 19910 30160
Re07.g07140 hypothetical protein 9661 1991 1 30161
Re07.g07150 hypothetical protein 9662 19912 30162
Re07.g07160 hypothetical protein 9663 19913 30163
Re07.g07170 Uncharacterized protein 9664 19914 30164
Putative CCAAT-box-binding
Re07.g07180 transcription factor (Eurofung) 9665 19915 30165
Re07.g07190 DNA polymerase epsilon subunit C 9666 19916 30166
Re07.g07200 Predicted protein 9667 19917 30167 32148 33638
Re07.g07210 hypothetical protein 9668 19918 30168
Re07.g07220 hypothetical protein 9669 19919 30169 32149 33639
Re07.g07230 hypothetical protein 9670 19920 30170
Re07.g07240 Putative uncharacterized protein 9671 19921 30171
Re07.g07250 Uncharacterized protein 9672 19922 30172
Re07.g07260 Similar to An12g02300 9673 19923 30173
Re07.g07270 Uncharacterized protein 9674 19924 30174
Re07.g07280 hypothetical protein 9675 19925 30175
Re07.g07290 Uncharacterized protein 9676 19926 30176
Re07.g07300 hypothetical protein 9677 19927 30177
Re07.g07310 hypothetical protein 9678 19928 30178
Re07.g07320 Peptide transporter MTD1 9679 19929 30179
Re07.g07330 hypothetical protein 9680 19930 30180
Re07.g07340 hypothetical protein 9681 19931 30181
Re07.g07350 Uncharacterized protein 9682 19932 30182 32150 33640
Re07.g07360 Putative uncharacterized protein 9683 19933 30183
Re07.g07370 Uncharacterized protein 9684 19934 30184
Re07.g07380 Putative uncharacterized protein 9685 19935 30185
Re07.g07390 MFS transporter, putative 9686 19936 30186
Re07.g07400 FAD binding domain protein 9687 19937 30187 32151 33641 Re07.g07410 4-coumarate-CoA ligase 9688 19938 30188
Glucosamine-phosphate N-
Re07.g07420 acetyltransferase 9689 19939 30189 32152 33642
Re07.g07430 hypothetical protein 9690 19940 30190
Re07.g07440 hypothetical protein 9691 19941 30191 32153 33643
Re07.g07450 Putative uncharacterized protein 9692 19942 30192
Re07.g07460 Multidrug resistance protein fnxl 9693 19943 30193
Re07.g07470 Putative uncharacterized protein 9694 19944 30194 32154 33644
Re07.g07480 hypothetical protein 9695 19945 30195
Re07.g07490 Putative uncharacterized protein 9696 19946 30196
Re07.g07500 Sugar transporter STL1 9697 19947 30197
Re07.g07510 Gluconolactonase 9698 19948 30198
Re07.g07520 Ankyrin, putative 9699 19949 30199
Re07.g07530 Maltose permease, putative 9700 19950 30200
Putative adp-ribosylation crystallin
Re07.g07540 j1 protein 9701 19951 30201
Re07.g07550 Uncharacterized protein 9702 19952 30202 32155 33645
Re07.g07560 Putative uncharacterized protein 9703 19953 30203
Glutamine-serine rich protein MS8,
Re07.g07570 putative 9704 19954 30204
Flavin containing polyamine
Re07.g07580 oxidase, putative 9705 19955 30205 32156 33646
Re07.g07590 Putative uncharacterized protein 9706 19956 30206
Re07.g07600 FAD-binding oxidoreductase 9707 19957 30207
Re07.g07610 Uncharacterized protein 9708 19958 30208
Re07.g07620 Cytochrome P450 monooxygenase 9709 19959 30209
Re07.g07630 Uncharacterized protein 9710 19960 30210
Re07.g07640 Uncharacterized protein 971 1 19961 3021 1 32157 33647
Re07.g07650 Similar to An01g14810 9712 19962 30212 32158 33648
Re07.g07660 Uncharacterized protein 9713 19963 30213 32159 33649
Re07.g07670 Carboxylesterase type B Fragment 9714 19964 30214 32160 33650
Re07.g07680 Reverse transcriptase, putative 9715 19965 30215
Re07.g07690 Putative uncharacterized protein 9716 19966 30216
Re08.g00010 hypothetical protein 9717 19967 30217
Gag/polymerase/env polyprotein,
Re08.g00020 putative 9718 19968 30218
Re08.g00030 Putative uncharacterized protein 9719 19969 30219
Transposon-encoded proteins with
Re08.g00040 TYA 9720 19970 30220
Small oligopeptide transporter,
Re08.g00050 OPT family protein 9721 19971 30221
Re08.g00060 Putative uncharacterized protein 9722 19972 30222
Nitrogen assimilation transcription
Re08.g00070 factor nirA 9723 19973 30223
Re08.g00080 Putative uncharacterized protein 9724 19974 30224
Re08.g00090 Fumarylacetoacetate hydrolase 9725 19975 30225
Re08.g00100 Uncharacterized protein 9726 19976 30226
Re08.g001 10 Amidohydrolase 9727 19977 30227
Re08.g00120 Uncharacterized protein 9728 19978 30228 Methyltransferase LaeA-like,
putative (AFU orthologue
Re08.g00130 AFUA_8G01930) 9729 19979 30229
Re08.g00140 Predicted protein 9730 19980 30230
Re08.g00150 hypothetical protein 9731 19981 30231
Re08.g00160 Putative uncharacterized protein 9732 19982 30232
Re08.g00170 Putative uncharacterized protein 9733 19983 30233
Re08.g00180 Monooxygenase, putative 9734 19984 30234
Re08.g00190 Cupin domain containing protein 9735 19985 30235
Re08.g00200 Putative uncharacterized protein 9736 19986 30236
Putative Zn(ll)2Cys6 transcription
Re08.g00210 factor (Eurofung) 9737 19987 30237
Putative uncharacterized protein
Re08.g00220 An08g04690 9738 19988 30238
Re08.g00230 UPF0075 domain protein 9739 19989 30239
Re08.g00240 Hexose carrier protein 9740 19990 30240
Re08.g00250 Pc12g08700 protein 9741 19991 30241
Re08.g00260 Putative uncharacterized protein 9742 19992 30242
Ubiquinone biosynthesis
Re08.g00270 methlytransferase Coq5, putative 9743 19993 30243
Putative sugar phosphate
isomerase involved in capsule
Re08.g00280 formation 9744 19994 30244
Nicotinamide mononucleotide
Re08.g00290 adenylyl transferase 9745 19995 30245
Ubiquitin-protein ligase Ufd4,
Re08.g00300 putative 9746 19996 30246 32161 33651
Re08.g00310 Thioesterase family protein 9747 19997 30247
Sister chromatid separation protein
Re08.g00320 (Src1 ), putative 9748 19998 30248
Re08.g00330 Adenylate cyclase AcyA 9749 19999 30249
Re08.g00340 hypothetical protein 9750 20000 30250
Re08.g00350 Pc20g03680 protein 9751 20001 30251
Re08.g00360 Tyrosyl-tRNA synthetase 9752 20002 30252
Phosphoglycerate mutase family
Re08.g00380 protein 9753 20003 30253
Re08.g00390 Uncharacterized protein 9754 20004 30254
Re08.g00400 Putative uncharacterized protein 9755 20005 30255
Re08.g00410 Similar to aquaporin 3 9756 20006 30256
Glycerol kinase, putative
Re08.g00420 EC=2.7.1.30 9757 20007 30257
Putative methyltransferase type 1 1
Re08.g00430 protein 9758 20008 30258
Re08.g00440 Uncharacterized protein 9759 20009 30259 32162 33652
Cytochrome P450 alkane
Re08.g00450 hydroxylase, putative 9760 20010 30260 32163 33653
Nuclear polyadenylated RNA-
Re08.g00460 binding protein Nab2, putative 9761 2001 1 30261 32164 33654
Re08.g00470 Protoporphyrinogen oxidase 9762 20012 30262 Re08.g00480 Putative uncharacterized protein 9763 20013 30263
Ubiquinol-cytochrome C reductase
Re08.g00490 complex, subunit X, putative 9764 20014 30264 32165 33655
Ubiquitin-protein ligase E3
Re08.g00500 component 9765 20015 30265
Re08.g00510 Putative uncharacterized protein 9766 20016 30266
Re08.g00520 hypothetical protein 9767 20017 30267
Re08.g00530 Uncharacterized protein 9768 20018 30268 32166 33656
Re08.g00540 hypothetical protein 9769 20019 30269 32167 33657
Re08.g00550 hypothetical protein 9770 20020 30270
Re08.g00560 hypothetical protein 9771 20021 30271
Re08.g00570 hypothetical protein 9772 20022 30272
Re08.g00580 hypothetical protein 9773 20023 30273
Re08.g00590 Uncharacterized protein 9774 20024 30274
Re08.g00600 Putative uncharacterized protein 9775 20025 30275
Re08.g00610 WD repeat protein 9776 20026 30276
Sphingomyelinase family protein,
Re08.g00620 putative 9777 20027 30277
Re08.g00630 Thiamine thiazole synthase 9778 20028 30278
Re08.g00640 Pc21 g04790 protein 9779 20029 30279 32168 33658
Re08.g00650 Retrograde regulation protein 2 9780 20030 30280
Re08.g00660 hypothetical protein 9781 20031 30281
Aspergillus niger contig
Re08.g00670 An01 c0080, genomic contig 9782 20032 30282
Re08.g00680 MFS transporter 9783 20033 30283
Re08.g00690 Putative uncharacterized protein 9784 20034 30284
Re08.g00700 Uncharacterized protein 9785 20035 30285
DNA-directed RNA polymerase
Re08.g00710 EC=2.7.7.6 9786 20036 30286
Proteasome subunit beta type
Re08.g00720 EC=3.4.25.1 9787 20037 30287
Re08.g00730 hypothetical protein 9788 20038 30288
Re08.g00740 Uncharacterized protein 9789 20039 30289
Re08.g00750 Putative uncharacterized protein 9790 20040 30290
Re08.g00760 Putative uncharacterized protein 9791 20041 30291
Re08.g00770 GMC oxidoreductase, putative 9792 20042 30292
Re08.g00780 Uncharacterized protein 9793 20043 30293
Pogo transposable element,
Re08.g00790 putative 9794 20044 30294
Re08.g00800 Predicted protein 9795 20045 30295 32169 33659
Re08.g00810 Putative uncharacterized protein 9796 20046 30296
Re08.g00820 Uncharacterized protein 9797 20047 30297
Re08.g00830 hypothetical protein 9798 20048 30298
Gag/polymerase/env polyprotein,
Re08.g00840 putative 9799 20049 30299
Re08.g00850 Uncharacterized protein 9800 20050 30300
Re08.g00860 Putative uncharacterized protein 9801 20051 30301
Re08.g00870 Uncharacterized protein 9802 20052 30302
Re08.g00880 Putative uncharacterized protein 9803 20053 30303 32170 33660 Re08.g00890 Uncharacterized protein 9804 20054 30304
Re08.g00900 Uncharacterized protein 9805 20055 30305 32171 33661
Re08.g00910 hypothetical protein 9806 20056 30306
Re08.g00920 CwfJ domain protein 9807 20057 30307
HEAT repeat protein (DRIM),
Re08.g00930 putative 9808 20058 30308
Mitochondrial import protein Zim17,
Re08.g00940 putative 9809 20059 30309
SCF ubiquitin ligase subunit CulC,
Re08.g00950 putative 9810 20060 30310
GINS DNA replication complex
Re08.g00960 subunit Sld5, putative 981 1 20061 3031 1
Cell cycle control protein tyrosine
Re08.g00970 phosphatase Mih1 , putative 9812 20062 30312
Re08.g00980 Tartrate dehydrogenase 9813 20063 30313
Re08.g00990 DNA polymerase V, putative 9814 20064 30314
Re08.g01000 MOSC domain 9815 20065 30315
Pyroglutamyl peptidase type I,
Re08.g01010 putative 9816 20066 30316
Re08.g01020 Putative uncharacterized protein 9817 20067 30317
Checkpoint protein kinase (SldA),
Re08.g01030 putative 9818 20068 30318
DNA (Apurinic or apyrimidinic site)
Re08.g01040 lyase, endon uclease 9819 20069 30319
Nucleotide-sugar transporter,
Re08.g01050 putative 9820 20070 30320
Re08.g01060 hypothetical protein 9821 20071 30321
Re08.g01070 Glycosyl hydrolase, putative 9822 20072 30322
Re08.g01080 Uncharacterized protein 9823 20073 30323
6-phosphogluconate
dehydrogenase, decarboxylating
Re08.g01090 EC=1.1.1.44 9824 20074 30324
Re08.g01 100 RNP domain protein 9825 20075 30325
Re08.g01 1 10 hypothetical protein 9826 20076 30326
Re08.g01 120 Putative uncharacterized protein 9827 20077 30327
Re08.g01 130 Uncharacterized protein 9828 20078 30328
Oxidoreductase, 20G-Fe(ll)
Re08.g01 140 oxygenase family 9829 20079 30329
Re08.g01 150 Cell division control protein 2 9830 20080 30330
Re08.g01 160 Calpain-like protein 9831 20081 30331
Re08.g01 170 Putative uncharacterized protein 9832 20082 30332
Re08.g01 180 hypothetical protein 9833 20083 30333
Re08.g01 190 Putative uncharacterized protein 9834 20084 30334
Re08.g01200 Uncharacterized protein 9835 20085 30335
Re08.g01210 hypothetical protein 9836 20086 30336
Phosphoglycerate mutase family
Re08.g01220 protein 9837 20087 30337
Re08.g01230 HECT domain protein 9838 20088 30338
Re08.g01240 C2H2 finger domain protein, 9839 20089 30339 putative
Re08.g01250 hypothetical protein 9840 20090 30340
DUF21 and CBS domain protein
Re08.g01260 (Mam3), putative 9841 20091 30341 32172 33662
Re08.g01270 Putative uncharacterized protein 9842 20092 30342
2-oxoisovalerate dehydrogenase
Re08.g01280 subunit beta 9843 20093 30343
Re08.g01290 Integral membrane protein 9844 20094 30344
Re08.g01300 Uncharacterized protein 9845 20095 30345
4-hydroxyphenylpyruvate
Re08.g01310 dioxygenase 9846 20096 30346
Homogentisate 1 ,2-dioxygenase
Re08.g01320 (HmgA), putative 9847 20097 30347
Re08.g01330 Uncharacterized protein 9848 20098 30348
Re08.g01340 Reverse transcriptase, putative 9849 20099 30349
Re08.g01350 Fumarylacetoacetase 9850 20100 30350 32173 33663
Maleylacetoacetate isomerase
Re08.g01360 MaiA 9851 20101 30351
Alpha- 1 ,2-mannosidase family
Re08.g01370 protein, putative 9852 20102 30352 32174 33664
Re08.g01380 C6 transcription factor, putative 9853 20103 30353
Cytomegalovirus gH-receptor
Re08.g01390 family protein, putative 9854 20104 30354
LaeA-like methyltransferase,
Re08.g01400 putative 9855 20105 30355
Re08.g01410 hypothetical protein 9856 20106 30356
Re08.g01420 Uncharacterized protein 9857 20107 30357
Re08.g01430 Uncharacterized protein 9858 20108 30358 32175 33665
Re08.g01440 Putative uncharacterized protein 9859 20109 30359
Re08.g01450 Cytochrome P450, putative 9860 201 10 30360 32176 33666
Re08.g01460 Putative uncharacterized protein 9861 201 1 1 30361 32177 33667
NADH-dependent flavin
Re08.g01470 oxidoreductase, putative 9862 201 12 30362
Cytochrome P450
Re08.g01480 monooxygenase, putative 9863 201 13 30363 32178 33668
Re08.g01490 Asparaginase, putative EC=3.5.1.1 9864 201 14 30364
Re08.g01500 Putative uncharacterized protein 9865 201 15 30365
Re08.g01510 hypothetical protein 9866 201 16 30366
Re08.g01520 hypothetical protein 9867 201 17 30367
Re08.g01530 hypothetical protein 9868 201 18 30368
Re08.g01540 Putative uncharacterized protein 9869 201 19 30369
Re08.g01550 hypothetical protein 9870 20120 30370 32179 33669
Re08.g01560 hypothetical protein 9871 20121 30371
Re08.g01570 hypothetical protein 9872 20122 30372
Chaperonin complex component,
Re08.g01580 TCP-1 epsilon subunit 9873 20123 30373
Re08.g01590 Heterochromatin protein, putative 9874 20124 30374
Re08.g01600 Uncharacterized protein 9875 20125 30375
Re08.g01610 Function: the function of CTR86 of 9876 20126 30376 32180 33670 S. cerevisiae is not yet clear
Re08.g01620 Putative uncharacterized protein 9877 20127 30377
Re08.g01630 Uncharacterized protein 9878 20128 30378
Re08.g01640 Uncharacterized protein 9879 20129 30379
Mannose-1 -phosphate
Re08.g01650 guanylyltransferase, variant 9880 20130 30380
Re08.g01660 Dynamin family protein 9881 20131 30381
Re08.g01670 Lysine-tRNA ligase EC=6.1.1.6 9882 20132 30382
Re08.g01680 hypothetical protein 9883 20133 30383
Cytochrome oxidase assembly
Re08.g01690 factor COX15 9884 20134 30384
Re08.g01700 Putative uncharacterized protein 9885 20135 30385
Re08.g01710 Putative uncharacterized protein 9886 20136 30386
Re08.g01720 mRNA cap methyltransferase 9887 20137 30387
Chromosomal organization and
DNA repair protein Mms21 ,
Re08.g01730 putative 9888 20138 30388
Mitochondrial dicarboxylate carrier
Re08.g01740 protein, putative 9889 20139 30389
Re08.g01750 hypothetical protein 9890 20140 30390
Re08.g01760 hypothetical protein 9891 20141 30391
Re08.g01770 hypothetical protein 9892 20142 30392
Re08.g01780 Uncharacterized protein 9893 20143 30393
Re08.g01790 hypothetical protein 9894 20144 30394
Re08.g01800 Uncharacterized protein 9895 20145 30395
Putative aldo keto reductase
Re08.g01810 protein 9896 20146 30396
Phosphoenol pyruvate
Re08.g01820 carboxykinase AcuF EC=4.1.1.49 9897 20147 30397
Re08.g01830 hypothetical protein 9898 20148 30398
Re08.g01840 Uncharacterized protein 9899 20149 30399
Re08.g01850 hypothetical protein 9900 20150 30400
Plasma membrane antiporter,
Re08.g01860 putative 9901 20151 30401 32181 33671
Peroxisomal biogenesis factor
Re08.g01870 (PEX1 1), putative 9902 20152 30402
MFS phospholipid transporter
Re08.g01880 (Git1 ), putative 9903 20153 30403
Re08.g01890 hypothetical protein 9904 20154 30404
Proteasome regulatory particle
Re08.g01900 subunit (RpnG), putative 9905 20155 30405
Alanine aminotransferase, putative
Re08.g01910 EC=2.6.1.2 9906 20156 30406
Re08.g01920 hypothetical protein 9907 20157 30407
Copper fist DNA binding domain
Re08.g01930 protein 9908 20158 30408
Re08.g01940 hypothetical protein 9909 20159 30409
Re08.g01950 C6 finger domain protein, putative 9910 20160 30410
Re08.g01960 Putative uncharacterized protein 991 1 20161 3041 1 Chromatin remodeling complex
Re08.g01970 subunit Fragment 9912 20162 30412
Re08.g01980 Uncharacterized protein 9913 20163 30413 32182 33672
Re08.g01990 Smr domain protein 9914 20164 30414
Methionine-R-sulfoxide reductase
Re08.g02000 SeIR, putative 9915 20165 30415
Stromal membrane-associated
Re08.g02010 protein 9916 20166 30416
Catabolite repressor protein
Re08.g02020 (CreC), putative 9917 20167 30417
Re08.g02030 Mitochondrial GTPase 9918 20168 30418
DUF500 and SH3 domain protein
Re08.g02040 (AFlLorthologue AFUA_6G07880) 9919 20169 30419
Telomere silencing protein Zds1 ,
Re08.g02050 putative 9920 20170 30420
Re08.g02060 Putative uncharacterized protein 9921 20171 30421
Re08.g02070 hypothetical protein 9922 20172 30422
Re08.g02080 Putative uncharacterized protein 9923 20173 30423 32183 33673
Carbon catabolite repression
Re08.g02090 protein CreD, putative 9924 20174 30424
Re08.g02100 PH domain protein 9925 20175 30425
GNAT family acetyltransferase,
Re08.g021 10 putative 9926 20176 30426
Re08.g02120 Putative uncharacterized protein 9927 20177 30427
Re08.g02130 Lactoylglutathione lyase 9928 20178 30428
Re08.g02140 Uncharacterized protein 9929 20179 30429
Re08.g02150 Uncharacterized protein 9930 20180 30430
Fe-containing alcohol
Re08.g02160 dehydrogenase, putative 9931 20181 30431
Re08.g02170 Uncharacterized protein 9932 20182 30432
Re08.g02180 BYS1 domain protein, putative 9933 20183 30433 32184 33674
Re08.g02190 Uncharacterized protein 9934 20184 30434 32185 33675
Re08.g02200 MFS quinate transporter 9935 20185 30435 32186 33676
Re08.g02210 hypothetical protein 9936 20186 30436
Re08.g02220 Transposase 9937 20187 30437
Putative o-methyltransferase
Re08.g02230 protein 9938 20188 30438
Re08.g02240 hypothetical protein 9939 20189 30439 32187 33677
Re08.g02250 hypothetical protein 9940 20190 30440
Peroxisomal membrane protein
Re08.g02260 (PmpP24), putative 9941 20191 30441
Ribosome biogenesis protein,
Re08.g02270 putative 9942 20192 30442
Re08.g02280 Uncharacterized protein 9943 20193 30443
Radical s-adenosyl methionine
Re08.g02290 domain containing protein 2 9944 20194 30444 32188 33678
Re08.g02300 Uncharacterized protein 9945 20195 30445
Re08.g02310 hypothetical protein 9946 20196 30446 32189 33679
Re08.g02320 Ribonuclease P complex subunit 9947 20197 30447 Pop2, putative
Re08.g02330 Casein kinase, putative 9948 20198 30448
Re08.g02340 Valyl-tRNA synthetase 9949 20199 30449
Re08.g02350 Uncharacterized protein 9950 20200 30450
Re08.g02360 Ankyrin repeat protein 9951 20201 30451
Re08.g02370 Uncharacterized protein 9952 20202 30452
Re08.g02380 Putative uncharacterized protein 9953 20203 30453
Re08.g02390 Uncharacterized protein 9954 20204 30454 32190 33680
Re08.g02400 hypothetical protein 9955 20205 30455
Re08.g02410 Uncharacterized protein 9956 20206 30456 32191 33681
Re08.g02420 Uncharacterized protein 9957 20207 30457
Re08.g02430 Similar to An12g02310 9958 20208 30458
Re08.g02440 Putative uncharacterized protein 9959 20209 30459
Re08.g02450 Predicted protein 9960 20210 30460
Re08.g02460 Putative uncharacterized protein 9961 2021 1 30461 32192 33682
Re08.g02470 hypothetical protein 9962 20212 30462 32193 33683
Re08.g02480 hypothetical protein 9963 20213 30463
Re08.g02490 Putative uncharacterized protein 9964 20214 30464 32194 33684
Re08.g02500 Putative uncharacterized protein 9965 20215 30465
Re08.g02510 Nucleolar protein 12 9966 20216 30466
Re08.g02520 hypothetical protein 9967 20217 30467
Transcriptional regulatory protein
Re08.g02530 DEP1 9968 20218 30468
Re08.g02540 Uncharacterized protein 9969 20219 30469
mRNA cleavage and
polyadenylation specificity factor
Re08.g02550 complex subunit 9970 20220 30470
Re08.g02560 hypothetical protein 9971 20221 30471
D-mandelate dehydrogenase,
Re08.g02570 putative 9972 20222 30472
Re08.g02580 hypothetical protein 9973 20223 30473
Oxidoreductase, short chain
dehydrogenase/reductase family,
Re08.g02590 putative 9974 20224 30474
Oligosaccharyl transferase subunit
Re08.g02600 (Stt3), putative 9975 20225 30475 32195 33685
COP9 signalosome subunit 8
Re08.g02610 (CsnH), putative 9976 20226 30476
Re08.g02620 Putative uncharacterized protein 9977 20227 30477 32196 33686
Re08.g02630 Dynein intermediate chain, putative 9978 20228 30478
Similar to putative non-ribosomal
Re08.g02640 peptide synthase 9979 20229 30479
Re08.g02650 MFS transporter, putative 9980 20230 30480
Re08.g02660 Uncharacterized protein 9981 20231 30481 32197 33687
Re08.g02670 Mannosyltransferase Pmtl 9982 20232 30482
NCS1 nucleoside transporter family
Re08.g02680 protein 9983 20233 30483
Re08.g02690 Putative uncharacterized protein 9984 20234 30484
Re08.g02710 Putative uncharacterized protein 9985 20235 30485 Re08.g02720 Putative uncharacterized protein 9986 20236 30486
Re08.g02730 Pirin, putative 9987 20237 30487 32198 33688
Re08.g02740 Putative uncharacterized protein 9988 20238 30488
Misfolded glycoproteins
Re08.g02750 degradation protein Yos9, putative 9989 20239 30489 32199 33689
Cytoskeleton assembly control
Re08.g02760 protein Sla1 , putative 9990 20240 30490
Cytochrome P450 alkane
Re08.g02770 hydroxylase, putative 9991 20241 30491 32200 33690
Re08.g02780 Sulfonate biosynthesis enzyme 9992 20242 30492
Re08.g02790 Integral membrane protein 9993 20243 30493 32201 33691
Re08.g02800 PWWP domain protein 9994 20244 30494
Re08.g02810 Putative uncharacterized protein 9995 20245 30495 32202 33692
Re08.g02820 Uncharacterized protein 9996 20246 30496
Re08.g02830 Uncharacterized protein 9997 20247 30497
Re08.g02840 DnaJ domain protein 9998 20248 30498 32203 33693
Re08.g02850 Uncharacterized protein Fragment 9999 20249 30499
Re08.g02860 hypothetical protein 10000 20250 30500
Re08.g02870 Predicted protein 10001 20251 30501
Re08.g02880 hypothetical protein 10002 20252 30502
Re08.g02890 Uncharacterized protein 10003 20253 30503
3-hydroxyanthranilate 3,4-
Re08.g02900 dioxygenase Bna1 , putative 10004 20254 30504
Re08.g02910 Nod p protein, putative 10005 20255 30505
Serine/threonine protein kinase,
Re08.g02920 putative 10006 20256 30506
sn-1 ,2-diacylglycerol
Re08.g02930 cholinephosphotransferase 10007 20257 30507 32204 33694
Re08.g02940 Uncharacterized protein 10008 20258 30508
Re08.g02950 Uncharacterized protein 10009 20259 30509
Small nuclear ribonucleoprotein
Re08.g02960 SmG 10010 20260 30510
Re08.g02970 Putative uncharacterized protein 1001 1 20261 3051 1
Re08.g02980 Uncharacterized protein 10012 20262 30512
Re08.g02990 hypothetical protein 10013 20263 30513
Re08.g03000 Putative uncharacterized protein 10014 20264 30514 32205 33695
Re08.g03010 hypothetical protein 10015 20265 30515
Re08.g03020 Uncharacterized protein 10016 20266 30516
Bis(5'-nucleosyl)-tetraphosphatase,
Re08.g03030 putative 10017 20267 30517
C2H2 finger domain protein,
Re08.g03040 putative 10018 20268 30518
Re08.g03050 hypothetical protein 10019 20269 30519
Re08.g03060 hypothetical protein 10020 20270 30520
Re08.g03070 hypothetical protein 10021 20271 30521
Re08.g03080 hypothetical protein 10022 20272 30522
Re08.g03090 Putative uncharacterized protein 10023 20273 30523
Re08.g03100 Putative uncharacterized protein 10024 20274 30524
Re08.g031 10 COP9 signalosome subunit 1 10025 20275 30525 (CsnA), putative
Re08.g03120 DSBA family oxidoreductase 10026 20276 30526
Short chain dehydrogenase family
Re08.g03130 protein 10027 20277 30527
Re08.g03140 Putative uncharacterized protein 10028 20278 30528
Re08.g03150 hypothetical protein 10029 20279 30529
Re08.g03160 hypothetical protein 10030 20280 30530 32206 33696
Re08.g03170 hypothetical protein 10031 20281 30531 32207 33697
Re08.g03180 hypothetical protein 10032 20282 30532 32208 33698
Re08.g03190 hypothetical protein 10033 20283 30533
Re08.g03200 RRNA processing protein, putative 10034 20284 30534
Re08.g03210 Uncharacterized protein 10035 20285 30535
Re08.g03220 Uncharacterized protein 10036 20286 30536
Re08.g03230 Predicted protein 10037 20287 30537
Re08.g03240 Uncharacterized protein 10038 20288 30538
Re08.g03250 Amino acid transporter 10039 20289 30539
Re08.g03260 Uncharacterized protein 10040 20290 30540 32209 33699
Re08.g03270 RING finger protein 10041 20291 30541 32210 33700
Re08.g03280 hypothetical protein 10042 20292 30542
Re08.g03290 Uncharacterized protein 10043 20293 30543
Re08.g03300 Putative uncharacterized protein 10044 20294 30544
Re08.g03310 MFS transporter, putative 10045 20295 30545 3221 1 33701
Re08.g03320 MFS quinate transporter, putative 10046 20296 30546
Nonribosomal peptide synthase,
Re08.g03330 putative EC=5.1.1.1 1 EC=5.1.1.13 10047 20297 30547
Re08.g03340 hypothetical protein 10048 20298 30548
Re08.g03350 ABC multidrug transporter, putative 10049 20299 30549
Re08.g03360 Predicted protein 10050 20300 30550 32212 33702
Re08.g03370 CCCH zinc finger protein 10051 20301 30551
DNA-directed RNA polymerase III
Re08.g03380 subunit RPC8 10052 20302 30552
Re08.g03390 Cystathionine gamma-lyase 10053 20303 30553
Re08.g03400 Transposase 10054 20304 30554
Re08.g03410 Putative uncharacterized protein 10055 20305 30555
NADH-ubiquinone oxidoreductase
Re08.g03420 178 kDa subunit 10056 20306 30556
Re08.g03430 Putative uncharacterized protein 10057 20307 30557
Re08.g03440 Uncharacterized protein 10058 20308 30558
Putative uncharacterized protein
Re08.g03450 An16g08780 10059 20309 30559
Re08.g03460 Predicted protein 10060 20310 30560
Re08.g03470 hypothetical protein 10061 2031 1 30561
Re08.g03480 hypothetical protein 10062 20312 30562
Re08.g03490 hypothetical protein 10063 20313 30563
Re08.g03500 Uncharacterized protein 10064 20314 30564
Oxidoreductase, short-chain
Re08.g03510 dehydrogenase/reductase family 10065 20315 30565
Re08.g03520 hypothetical protein 10066 20316 30566
Re08.g03530 Uncharacterized protein 10067 20317 30567 Re08.g03540 Uncharacterized protein 10068 20318 30568
40S ribosomal protein S15,
Re08.g03550 putative 10069 20319 30569 32213 33703
Re08.g03560 Uncharacterized protein 10070 20320 30570
Carbamoyl-phosphate synthase,
Re08.g03570 large subunit EC=6.3.4.16 10071 20321 30571
Re08.g03580 Putative uncharacterized protein 10072 20322 30572
Re08.g03590 Transposon, putative 10073 20323 30573
Re08.g03600 Uncharacterized protein 10074 20324 30574
Re08.g03610 G-patch domain protein, putative 10075 20325 30575
Re08.g03620 Triacylglycerol lipase, putative 10076 20326 30576 32214 33704 rRNA maturation protein (Nop14),
Re08.g03630 putative 10077 20327 30577
Re08.g03640 Uncharacterized protein Fragment 10078 20328 30578 32215 33705
Re08.g03650 Pc21 g1 1 140 protein 10079 20329 30579
Re08.g03660 Pentatricopeptide repeat protein 10080 20330 30580
Translocation protein (Sec66),
Re08.g03670 putative 10081 20331 30581 32216 33706
Re08.g03680 AAA family ATPase, putative 10082 20332 30582
Cleavage and polyadenylation
Re08.g03690 specificity factor subunit A, putative 10083 20333 30583
Re08.g03700 LMBR1 domain protein, putative 10084 20334 30584
Re08.g03710 Uncharacterized protein 10085 20335 30585
Re08.g03720 Putative uncharacterized protein 10086 20336 30586
Re08.g03730 ZIP family zinc transporter, putative 10087 20337 30587
Acetyl-CoA acetyltransferase,
Re08.g03740 putative 10088 20338 30588 32217 33707
U5 small nuclear ribonucleoprotein
Re08.g03750 component 10089 20339 30589
Re08.g03760 Uncharacterized protein 10090 20340 30590
Re08.g03770 C6 finger domain protein 10091 20341 30591
Re08.g03780 Uncharacterized protein 10092 20342 30592
Re08.g03790 Ribosome recycling factor, putative 10093 20343 30593
Re08.g03800 Heat shock protein SSB 10094 20344 30594
Re08.g03810 Uncharacterized protein 10095 20345 30595
Cyclin-dependent kinase regulatory
Re08.g03820 subunit 10096 20346 30596
Re08.g03830 Uncharacterized protein 10097 20347 30597
Re08.g03840 Uncharacterized protein 10098 20348 30598 32218 33708
Re08.g03850 Uncharacterized protein 10099 20349 30599
Peptidyl-prolyl cis-trans isomerase
Re08.g03860 EC=5.2.1.8 10100 20350 30600
Alanyl-tRNA synthetase,
Re08.g03870 cytoplasmic 10101 20351 30601
Re08.g03880 Putative uncharacterized protein 10102 20352 30602
Re08.g03890 hypothetical protein 10103 20353 30603
Re08.g03900 Uncharacterized protein 10104 20354 30604
Re08.g03910 Putative uncharacterized protein 10105 20355 30605
Re08.g03920 Putative uncharacterized protein 10106 20356 30606 Re08.g03930 Putative uncharacterized protein 10107 20357 30607
Re08.g03940 Uncharacterized protein Fragment 10108 20358 30608 32219 33709
Re08.g03950 hypothetical protein 10109 20359 30609
Re08.g03960 Reverse transcriptase, putative 101 10 20360 30610
Re08.g03970 Putative uncharacterized protein 101 1 1 20361 3061 1
Re08.g03980 Putative uncharacterized protein 101 12 20362 30612
Re08.g03990 Putative uncharacterized protein 101 13 20363 30613
Re08.g04000 hypothetical protein 101 14 20364 30614
Re08.g04010 Putative uncharacterized protein 101 15 20365 30615
Re08.g04020 AMP deaminase 101 16 20366 30616
Re08.g04030 hypothetical protein 101 17 20367 30617
Re08.g04040 hypothetical protein 101 18 20368 30618
Re08.g04050 Putative uncharacterized protein 101 19 20369 30619
Re08.g04060 hypothetical protein 10120 20370 30620
Variant SH3 domain containing
Re08.g04070 protein 10121 20371 30621
Re08.g04080 Predicted protein 10122 20372 30622 32220 33710
Dynamin-like GTPase Dnm1 ,
Re08.g04090 putative 10123 20373 30623
Re08.g04100 hypothetical protein 10124 20374 30624
UDP-N-acetylglucosamine
Re08.g041 10 transporter YEA4 10125 20375 30625
Re08.g04120 Pc16g01 160 protein 10126 20376 30626
Re08.g04130 Pc16g01 150 protein 10127 20377 30627
Protein phosphatase type 1
complex subunit Hex2/Reg1 ,
Re08.g04140 putative 10128 20378 30628
Re08.g04150 hypothetical protein 10129 20379 30629
RNA binding protein Tma22,
Re08.g04160 putative 10130 20380 30630
Re08.g04170 Uncharacterized protein 10131 20381 30631
Re08.g04180 rRNA-processing protein cgrA 10132 20382 30632
Mitochondrial ornithine carrier
Re08.g04190 protein AmcA/Ort1 , putative 10133 20383 30633
Re08.g04200 Uncharacterized protein 10134 20384 30634
Vacuolar protein sorting protein,
Re08.g04210 putative 10135 20385 30635 32221 3371 1
Re08.g04220 Uncharacterized protein 10136 20386 30636
Re08.g04230 hypothetical protein 10137 20387 30637
Re08.g04240 Uncharacterized protein 10138 20388 30638
Putative undecaprenyl diphosphate
Re08.g04250 synthase 10139 20389 30639
Re08.g04260 Putative uncharacterized protein 10140 20390 30640
Re08.g04270 Repressor protein 10141 20391 30641
Re08.g04280 C6 transcription factor, putative 10142 20392 30642
Re08.g04290 hypothetical protein 10143 20393 30643
Putative acetyl xylan esterase
Re08.g04300 protein 10144 20394 30644 32222 33712
Re08.g04310 hypothetical protein 10145 20395 30645 Re08.g04320 Polyamine transporter, putative 10146 20396 30646
Re08.g04330 hypothetical protein 10147 20397 30647
Re08.g04340 O-methyltransferase, putative 10148 20398 30648 32223 33713
Re08.g04350 Uncharacterized protein 10149 20399 30649
Re08.g04360 Uncharacterized protein 10150 20400 30650
Re08.g04370 hypothetical protein 10151 20401 30651 32224 33714
Re08.g04380 hypothetical protein 10152 20402 30652
Re08.g04390 hypothetical protein 10153 20403 30653
Re08.g04400 hypothetical protein 10154 20404 30654
Re08.g04410 hypothetical protein 10155 20405 30655
Re08.g04420 hypothetical protein 10156 20406 30656
Re08.g04430 hypothetical protein 10157 20407 30657 32225 33715
Re08.g04440 hypothetical protein 10158 20408 30658
Similarity to hypothetical
transcriptions regulator
Re08.g04450 CAB91400.2 10159 20409 30659 32226 33716
Re08.g04460 Uncharacterized protein 10160 20410 30660
Re08.g04470 Transketolase, putative 10161 2041 1 30661
Re08.g04480 Alcohol dehydrogenase, putative 10162 20412 30662
Re08.g04490 Guanylate kinase 10163 20413 30663
Re08.g04500 Pc14g00200 protein 10164 20414 30664
Re08.g04510 Uncharacterized protein 10165 20415 30665
Re08.g04520 hypothetical protein 10166 20416 30666
Putative hydrolase or
acyltransferase of alpha/beta
Re08.g04530 superfamily 10167 20417 30667
Na/K ATPase alpha 1 subunit,
Re08.g04540 putative 10168 20418 30668
Re08.g04550 Predicted protein 10169 20419 30669
Re08.g04560 Potassium transporter, putative 10170 20420 30670
Re08.g04570 hypothetical protein 10171 20421 30671
Re08.g04580 Reverse transcriptase, putative 10172 20422 30672
Re08.g04590 Terpene synthase family protein 10173 20423 30673
Re08.g04600 Cytochrome P450, putative 10174 20424 30674
Re08.g04610 Putative uncharacterized protein 10175 20425 30675 32227 33717
Re08.g04630 hypothetical protein 10176 20426 30676
Re08.g04640 Predicted protein 10177 20427 30677
Zinc binding dehydrogenase,
Re08.g04650 putative 10178 20428 30678
Re08.g04670 Uncharacterized protein 10179 20429 30679
Putative taurine catabolism
Re08.g04680 dioxygenase 10180 20430 30680
Re08.g04690 Rhamnogalacturonase, putative 10181 20431 30681 32228 33718
Re08.g04700 Putative uncharacterized protein 10182 20432 30682 32229 33719
Re08.g04710 Uncharacterized protein 10183 20433 30683
Re08.g04720 Putative uncharacterized protein 10184 20434 30684
Re08.g04730 Predicted protein 10185 20435 30685
Re08.g04740 Uncharacterized protein 10186 20436 30686 32230 33720
Re08.g04750 Putative uncharacterized protein 10187 20437 30687 Glutamic protease eqolisin
Re08.g04760 EC=3.4.23.19 10188 20438 30688 32231 33721
Re08.g04770 hypothetical protein 10189 20439 30689
Re08.g04780 Glycoside hydrolase family 20 10190 20440 30690 32232 33722
Re08.g04790 Uncharacterized protein 10191 20441 30691
Re08.g04800 TfdA family taurine dioxygenase 10192 20442 30692
Alpha-ketoglutarate-dependent 2,4- dichlorophenoxyacetate
Re08.g04820 dioxygenase 10193 20443 30693
Re08.g04830 Secreted protein 10194 20444 30694 32233 33723
Re08.g04840 Uncharacterized protein 10195 20445 30695
Re08.g04850 Uncharacterized protein 10196 20446 30696 32234 33724
Re08.g04860 Maltose permease, putative 10197 20447 30697 32235 33725
Re08.g04870 Putative uncharacterized protein 10198 20448 30698
Re08.g04880 FAD binding domain protein 10199 20449 30699 32236 33726
Re08.g04890 Putative uncharacterized protein 10200 20450 30700
Re08.g04900 Uncharacterized protein 10201 20451 30701
Re08.g04910 Pc22g08620 protein 10202 20452 30702
Re08.g04920 C6 transcription factor, putative 10203 20453 30703
Re08.g04930 Disulfide oxidoreductase, putative 10204 20454 30704
Re08.g04940 Putative transporter MCH4 10205 20455 30705
Monocarboxylate permease
Re08.g04950 homologue, mch4 10206 20456 30706
Re08.g04960 Major facilitator superfamily 10207 20457 30707 32237 33727
Re08.g04970 hypothetical protein 10208 20458 30708
Re08.g04980 FAD dependent oxidoreductase 10209 20459 30709
Putative uncharacterized protein
Re08.g04990 AO090005000062 10210 20460 30710
Similar to monooxygenase FAD-
Re08.g05000 binding 1021 1 20461 3071 1
Re08.g05010 hypothetical protein 10212 20462 30712
Re10.g00010 Cytochrome P450, putative 10213 20463 30713
Re10.g00020 Terpene synthase family protein 10214 20464 30714
Re10.g00030 hypothetical protein 10215 20465 30715
Re10.g00040 hypothetical protein 10216 20466 30716
Re10.g00050 hypothetical protein 10217 20467 30717
Re10.g00060 Potassium transporter, putative 10218 20468 30718
Re10.g00070 Predicted protein 10219 20469 30719
Re10.g00080 hypothetical protein 10220 20470 30720 32238 33728
Re10.g00090 Na+/K+ ATPase, alpha subunit 10221 20471 30721
Re1 1.g00010 hypothetical protein 10222 20472 30722
Re1 1.g00020 hypothetical protein 10223 20473 30723
Re1 1.g00030 Putative uncharacterized protein 10224 20474 30724
Re1 1.g00040 Reverse transcriptase, putative 10225 20475 30725
Putative uncharacterized protein
Re1 1.g00050 Fragment 10226 20476 30726
Re1 1.g00060 Uncharacterized protein Fragment 10227 20477 30727
Transposon-encoded proteins with
Re1 1.g00070 TYA 10228 20478 30728 Re11.g00080 Putative uncharacterized protein 10229 20479 30729
Re12.g00010 hypothetical protein 10230 20480 30730
Viral A-type inclusion protein
Re12.g00020 repeat protein 10231 20481 30731
Re12.g00030 Reverse transcriptase, putative 10232 20482 30732
Re12.g00040 Reverse transcriptase, putative 10233 20483 30733
Re12.g00050 hypothetical protein 10234 20484 30734
Re12.g00060 Putative uncharacterized protein 10235 20485 30735
Re12.g00070 Reverse transcriptase, putative 10236 20486 30736 32239 33729
Re12.g00080 Reverse transcriptase, putative 10237 20487 30737
Re12.g00090 Reverse transcriptase, putative 10238 20488 30738
Re12.g00100 Putative uncharacterized protein 10239 20489 30739
Endonuclease/reverse
Re13.g00010 transcriptase, putative 10240 20490 30740
Re13.g00020 Putative uncharacterized protein 10241 20491 30741
Re13.g00030 hypothetical protein 10242 20492 30742
Re13.g00040 hypothetical protein 10243 20493 30743
Pyruvate dehydrogenase E1
component alpha subunit,
Re13.g00050 mitochondrial 10244 20494 30744 32240 33730
Re14.g00010 hypothetical protein 10245 20495 30745
Re14.g00020 Uncharacterized protein 10246 20496 30746
Re14.g00030 C6 transcription factor 10247 20497 30747
Re14.g00040 Putative uncharacterized protein 10248 20498 30748
Re14.g00050 Putative uncharacterized protein 10249 20499 30749
ATP-binding cassette, subfamily B
Re14.g00060 (MDR/TAP), member 1 10250 20500 30750
Detailed description of the invention
Throughout the present specification and the accompanying claims, the words "comprise" and "include" and variations such as "comprises", "comprising", "includes" and "including" are to be interpreted inclusively. That is, these words are intended to convey the possible inclusion of other elements or integers not specifically recited, where the context allows.
The articles "a" and "an" are used herein to refer to one or to more than one (i.e. to one or at least one) of the grammatical object of the article. By way of example, "an element" may mean one element or more than one element.
The term "derived from" also includes the terms "originated from," "obtained from," "obtainable from," "isolated from," and "created from," and generally indicates that one specified material find its origin in another specified material or has features that can be described with reference to the another specified material. As used herein, a substance (e.g., a nucleic acid molecule or polypeptide) "derived from" a microorganism preferably means that the substance is native to that microorganism. The present invention provides polynucleotides encoding polypeptides, e.g. enzymes which have the ability to modify, for example degrade, a carbohydrate material. A carbohydrate material is a material which comprises, consists of or substantially consists of one or more carbohydrates. Enzymes are herein a subclass of polypeptides.
Substrate (also called feedstock, lignocellulosic material, biomass) herein is used to refer to a substance that comprises carbohydrate material, which may be treated with enzymes according to the invention, so that the carbohydrate material therein is modified. The substrate may be pretreated or non-pretreated substrate. In addition to the carbohydrate material the substrate may contain any other component, including but not limited to non-carbohydrate material and starch.
The present invention provides DNA of Rasamsonia emersonii. This DNA contains nucleotide sequences or polynucleotides such as genes, regulatory elements and other nucleotide sequences. The present invention also relates to polypeptides having preferably biological activity which comprise an amino acid sequence encoded by a nucleotide sequence. For example polypeptides of the invention such as enzymes, may have the ability to modify, for example degrade, a carbohydrate material. A carbohydrate material is a material which comprises, consists of or substantially consists of one or more carbohydrates. Enzymes are herein a subclass of polypeptides.
The present invention will be exemplified by the degradation of lignocellulosic material. These examples are used to show in more detail part of the invention. The present invention may be used in other fields as well, for example, in the preparation of a food product, in the preparation of a detergent, in the preparation of an animal feed, in the treatment of pulp or in the manufacture of a paper or in the preparation of a fabric or textile or in the cleaning thereof,
Typically, a polynucleotide of the invention encodes a polypeptide having preferably biological activity and having an amino acid sequence according to SEQ ID NO: SEQ ID NO: 20501 to 32240, or a sequence which is a variant thereof, typically functionally equivalent to the polypeptide having the sequence of SEQ ID NO: SEQ ID NO: 20501 to 32240, or a sequence which is a fragment of either thereof.
A polypeptide of the invention may have biological activity. A polypeptide of the invention may have one or more alternative and/or additional biological activities, for example one of the other biological activities mentioned herein. Carbohydrate in this context includes all saccharides, for example polysaccharides, oligosaccharides, disaccharides or monosaccharides.
According to one aspect of the invention the use of the polypeptide of the inventionis provided and as well as compositions useful in industrial processes.
Despite the long term experience obtained with these processes, the polypeptide, such as an enzyme, according to the invention may feature a number of significant advantages over enzymes currently used. Depending on the specific application, these advantages may include aspects such as lower production costs, higher specificity towards the substrate, reduced antigenicity, fewer undesirable side activities, higher yields when produced in a suitable microorganism, more suitable pH and temperature ranges, non-inhibition by hydrophobic, lignin-derived products or less product inhibition or, in the case of the food industry a better taste or texture of a final product as well as food grade and kosher aspects.
Advantageously the polypeptide of the invention or the amended expression of the polypeptide of the invention may have a yield increasing effect on top of or in a composition preferably an enzyme composition designed for for example (feedstock) hydrolysis such as the compositions produced by TEC-147, TEC-210 or 4E mix (see Examples) or other suitable compositions including commercial compositions such as Celluclast ® combined with Novozyme 188 (obtainable from Novozymes, Denmark or Sigma-Aldrich®, USA), Accellerase ® 1000 (obtainable from Genencor, USA or Sigma- Aldrich®, USA), and Methaplus ® (obtainable from DSM, Netherlands). This yield increasing effect may be shown by replacing part of the enzyme composition by an equal amount (on protein) of a composition of the invention. This yield increasing effect may also be shown as an increase (in %) of activity of the enzyme composition which increase is higher than the increase (in %) of added polypeptide according to the invention (in protein). This yield increase is even possible in case of feedstock such as corn stover. This yield increase can be shown for example as an increase of the amount of glucose released during a fixed reaction (hydrolysis) period of time compared to the situation without the addition of the present composition or polypeptide, or this yield increase can be shown as an similar amount of glucose production with a lower dosage of the 4E or TEC-210 compared to the situation without the addition of the present composition or polypeptide to the regular dosage of the 4E or TEC-210.
According to a preferred embodiment the polypeptide of the invention is a "thermostable" polypeptide. In another preferred embodiment, the polynucleotide according to the invention encodes a "thermostable" polypeptide. Herein, "thermostable" polypeptide means that the polypeptide has a temperature optimum of 60 °C or higher, for example 70 °C or higher, such as 75 °C or higher, for example 80 °C or higher such as 85 °C or higher. In general the temperature optimum will be lower than 95 °C. The temperature optimum is the optimum activity of the polypeptide measured during one hour at optimum pH conditions.
According to a preferred embodiment the polypeptide of the invention has a pH optimum in between pH 2 and pH 8. Preferably, the polypeptide has a pH optimum of 6 or lower, more preferably 5 or lower, for example 4.5 or lower, such as 4 or lower, for example 3.5 or lower. Preferably, the polypeptide has a pH optimum of 2 or higher, preferably 2.5 or higher. The pH optimum is the optimum activity of the polypeptide measured during 48 hours at optimum temperature conditions.
The present invention relates to DNA of Rasamsonia emersonii. This DNA contains nucleotide sequences such as genes, regulatory elements and other nucleotide sequences. The present invention therefore also relates to regulatory elements and other nucleotide sequences. These regulatory elements and other nucleotide sequences may be used to influence processes which take place in the (host) cell. For example a promoter sequence may be used to increase the expression of a desired protein or polypeptide.
Suitable carbohydrate materials
Lignocellulolytic or lignocellulosic materials or biomass are abundant in nature and have great value as alternative energy source. Second generation biofuels, also known as advanced biofuels, are fuels that can be manufactured from various types of biomass. Biomass is a wide-ranging term meaning any source of organic carbon that is renewed rapidly as part of the carbon cycle. Biomass is derived from plant materials but can also include animal materials. The composition of lignocellulosic biomass varies, the major component is cellulose (in general 35-50%), followed by xylan (in general 20-35%, a type of hemicellulose) and lignin (in general 10-25%), in addition to minor components such as proteins, oils and ash that make up the remaining fraction of lignocellulosic biomass. Lignocellulosic biomass contains a variety of carbohydrates. The term carbohydrate is most common in biochemistry, where it is a synonym of saccharide. Carbohydrates (saccharides) are divided into four chemical groupings: monosaccharides, disaccharides, oligosaccharides, and polysaccharides. In general, monosaccharides and disaccharides, which are smaller (lower molecular weight) carbohydrates, are commonly referred to as sugars.
A non-starch carbohydrate suitable for modification by an enzyme composition produced using the invention or a polypeptide of the invention is lignocellulose. The major polysaccharides comprising different lignocellulosic residues, which may be considered as a potential renewable feedstock, are cellulose (glucans), hemicelluloses (xylans, heteroxylans and xyloglucans). In addition, some hemicellulose may be present as glucomannans, for example in wood-derived feedstocks. The enzymatic hydrolysis of these polysaccharides to soluble sugars, for example glucose, xylose, arabinose, galactose, fructose, mannose, rhamnose, ribose, D-galacturonic acid and other hexoses and pentoses occurs under the action of different enzymes acting in concert.
Lignin fills the spaces in the cell wall between cellulose, hemicellulose, and pectin components, especially in xylem tracheids, vessel elements and sclereid cells. It is covalently linked to hemicellulose and, therefore, crosslinks different plant polysaccharides, conferring mechanical strength to the cell wall and by extension the plant as a whole. Lignin is a highly hydrophobic crosslinked aromatic polymeric material that is formed by different monolignol monomers, which can be methoxylated to various degrees. There are three monolignol monomers, methoxylated to various degrees: p- coumaryl alcohol, coniferyl alcohol, and sinapyl alcohol. These lignols are incorporated into lignin in the form of the phenylpropanoids p-hydroxyphenyl (H), guaiacyl (G), and syringyl (S), respectively. Biodegradation of lignin is a prerequisite for processing biofuel from plant raw materials. Lignin can be degraded by applying different pretreatment methods, or by using ligninases or lignin-modifying enzymes (LME's). The improving of lignin degradation would drive the output from biofuel processing to better gain or better efficiency factor, for example by improving the accessibility to the (hemi)cellulosic components or by removing lignin-(hemi)cellulose linkages in oligosaccharides released by the action of (hemi)cellulases.
In addition, pectins and other pectic substances such as arabinans may make up considerably proportion of the dry mass of typically cell walls from non-woody plant tissues (about a quarter to half of dry mass may be pectins).
Cellulose is a linear polysaccharide composed of glucose residues linked by β- 1 ,4 bonds. The linear nature of the cellulose fibers, as well as the stoichiometry of the β- linked glucose (relative to a) generates structures more prone to interstrand hydrogen bonding than the highly branched olinked structures of starch. Thus, cellulose polymers are generally less soluble, and form more tightly bound fibers than the fibers found in starch.
Hemicellulose is a complex polymer, and its composition often varies widely from organism to organism and from one tissue type to another. In general, a main component of hemicellulose is β-1 ,4-linked xylose, a five carbon sugar. However, this xylose is often branched at 0-3 and/or 0-2 and can be substituted with linkages to arabinose, galactose, mannose, glucuronic acid, galacturonic acid or by esterification to acetic acid (and esterification of ferulic acid to arabinose). Hemicellulose can also contain glucan, which is a general term for β-linked six carbon sugars (such as the β- (1 ,3)(1 ,4) glucans and heteroglucans mentioned previously) and additionally glucomannans (in which both glucose and mannose are present in the linear backbone, linked to each other by β-linkages).
The composition, nature of substitution, and degree of branching of hemicellulose is very different in dicotyledonous plants (dicots, i.e., plant whose seeds have two cotyledons or seed leaves such as lima beans, peanuts, almonds, peas, kidney beans) as compared to monocotyledonous plants (monocots; i.e., plants having a single cotyledon or seed leaf such as corn, wheat, rice, grasses, barley). In dicots, hemicellulose is comprised mainly of xyloglucans that are 1 ,4-3-linked glucose chains with 1 ,θ-β-linked xylosyl side chains. In monocots, including most grain crops, the principal components of hemicellulose are heteroxylans. These are primarily comprised of 1 ,4-3-linked xylose backbone polymers with 1 ,3 -a linkages to arabinose, galactose, mannose and glucuronic acid or 4-O-methyl-glucuronic acid as well as xylose modified by ester-linked acetic acids. Also present are β glucans comprised of 1 ,3- and 1 ,4-β- linked glucosyl chains. In monocots, cellulose, heteroxylans and β-glucans may be present in roughly equal amounts, each comprising about 15-25% of the dry matter of cell walls. Also, different plants may comprise different amounts of, and different compositions of, pectic substances. For example, sugar beet contains about 19% pectin and about 21 % arabinan on a dry weight basis.
Accordingly, an enzyme composition produced using the invention or a composition of the invention may be tailored in view of the particular feedstock (also called substrate) which is to be used. That is to say, the spectrum of activities in a composition of the invention may vary depending on the feedstock in question.
Enzyme combinations or physical treatments can be administered concomitantly or sequentially. The enzymes can be produced either exogenously in microorganisms, yeasts, fungi, bacteria or plants, then isolated and added to the lignocellulosic feedstock or lignocellulosic material. Alternatively, the enzymes are produced, but not isolated, and crude cell mass fermentation broth are added to the feedstock. Alternatively, the crude cell mass or enzyme production medium or plant material may be treated to prevent further microbial growth (for example, by heating or addition of antimicrobial agents), then added to the feedstock. These crude enzyme mixtures may include the organism producing the enzyme. Alternatively, the enzyme may be produced in a fermentation that uses feedstock (such as corn stover) to provide nutrition to an organism that produces an enzyme(s). In this manner, plants that produce the enzymes may serve as the lignocellulosic feedstock and be added into lignocellulosic feedstock.
Enzymatic activity
Endo-1 ,4-3-glucanases (EG) and exo-cellobiohydrolases (CBH) catalyze the hydrolysis of insoluble cellulose to cellooligosaccharides (cellobiose as a main product), while β-glucosidases (BGL) convert the oligosaccharides, mainly cellobiose and cellotriose to glucose.
Xylanases together with other accessory enzymes, for example a-L- arabinofuranosidases, feruloyl and acetylxylan esterases, glucuronidases, and β- xylosidases) catalyze the hydrolysis of part of the hemicelluloses.
Pectic substances include pectins, arabinans, galactans and arabinogalactans. Pectins are the most complex polysaccharides in the plant cell wall. They are built up around a core chain of a(1 ,4)-linked D-galacturonic acid units interspersed to some degree with L-rhamnose. In any one cell wall there are a number of structural units that fit this description and it has generally been considered that in a single pectic molecule, the core chains of different structural units are continuous with one another.
Pectinases include, for example an endo-polygalacturonase, a pectin methyl esterase, an endo-galactanase, a β-galactosidase, a pectin acetyl esterase, an endo- pectin lyase, pectate lyase, a-rhamnosidase, an exo-galacturonase, an exo- polygalacturonate lyase, a rhamnogalacturonan hydrolase, a rhamnogalacturonan lyase, a rhamnogalacturonan acetyl esterase, a rhamnogalacturonan galacturonohydrolase, a xylogalacturonase, an oarabinofuranosidase.
The principal types of structural unit are: galacturonan (homogalacturonan), which may be substituted with methanol on the carboxyl group and acetate on 0-2 and 0-3; rhamnogalacturonan I (RGI), in which galacturonic acid units alternate with rhamnose units carrying (1 ,4)-linked galactan and (1 ,5)-linked arabinan side-chains. The arabinan side-chains may be attached directly to rhamnose or indirectly through the galactan chains; xylogalacturonan, with single xylosyl units on 0-3 of galacturonic acid (closely associated with RGI); and rhamnogalacturonan II (RGII), a particularly complex minor unit containing unusual sugars, for example apiose. An RGII unit may contain two apiosyl residues which, under suitable ionic conditions, can reversibly form esters with borate.
As set out above, a polypeptide of the invention will typically have biological activity. However, a polypeptide of the invention may have one or more biological activities set out above in addition to or alternative to that activity. Also, a composition of the invention as described herein may have one or more of the biological activities mentioned above in addition to that provided by the polypeptide of the invention.
Polynucleotide sequence
The invention provides genomic polynucleotide sequences comprising the gene encoding the protein or polypeptide of the invention as well as its coding sequence. Accordingly, the invention relates to an isolated polynucleotide comprising the genomic nucleotide sequence according to the coding nucleotide sequence according to SEQ ID NO: 1 to 20500 and to variants, such as functional equivalents, of either thereof.
In particular, the invention relates to an isolated polynucleotide which is capable of hybridizing selectively, for example under stringent conditions, preferably under highly stringent conditions, with the reverse complement of a polynucleotide comprising the sequence set out in SEQ ID NO: 1 to 20500.
More specifically, the invention relates to a polynucleotide comprising or consisting essentially of a nucleotide sequence according to SEQ ID NO: 1 to 20500.
The invention also relates to an isolated polynucleotide comprising or consisting essentially of a sequence which encodes at least one functional domain of a polypeptide according to SEQ ID NO: SEQ ID NO: 20501 to 32240 or a variant thereof, such as a functional equivalent, or a fragment of either thereof.
In one embodiment, the protein or polypeptide of the invention nucleic acid of the invention is at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 91 %, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or more homologous to a nucleic acid sequence shown in SEQ ID NO: 1 to 20500 or the complement thereof. The term "gene" as used herein refers to a segment of a nucleic acid molecule coding for a polypeptide chain, that may or may not include gene regulatory sequences preceding and following the coding sequence, e.g. promoters, enhancers, etc., as well as intervening sequences (introns) between individual coding segments (exons). It will further be appreciated that the definition of gene can include nucleic acids that do not encode polypeptide, but rather provide templates for transcription of functional RNA molecules such as tRNAs, rRNAs, etc.
A nucleic acid molecule of the present invention, such as a nucleic acid molecule having the nucleotide sequence of SEQ ID NO: 1 to 20500 or a variant thereof, such as a functional equivalent, can be isolated using standard molecular biology techniques and the sequence information provided herein. For example, using all or a portion of the nucleic acid sequence of SEQ ID NO: 1 to 20500 as a hybridization probe, nucleic acid molecules according to the invention can be isolated using standard hybridization and cloning techniques (e. g., as described in Sambrook, J., Fritsh, E. F., and Maniatis, T. Molecular Cloning: A Laboratory Manual.2nd, ed., Cold Spring Harbor Laboratory, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1989).
Moreover, a nucleic acid molecule encompassing all or a portion of SEQ ID NO: 1 to 20500 may be isolated by the polymerase chain reaction (PCR) using synthetic oligonucleotide primers designed based upon the sequence information contained in SEQ ID NO: 1 to 20500.
A nucleic acid of the invention can be amplified using cDNA, mRNA or alternatively, genomic DNA, as a template and appropriate oligonucleotide primers according to standard PCR amplification techniques. The nucleic acid so amplified can be cloned into an appropriate vector and characterized by DNA sequence analysis.
Furthermore, oligonucleotides corresponding to or hybridizable to a nucleotide sequence according to the invention can be prepared by standard synthetic techniques, e.g., using an automated DNA synthesizer.
In a preferred embodiment, an isolated nucleic acid molecule of the invention comprises the nucleotide sequence shown in SEQ ID NO: 1 to 20500.
In another preferred embodiment, an isolated nucleic acid molecule of the invention comprises a nucleic acid molecule which is the reverse complement of the nucleotide sequence shown in SEQ ID NO: 1 to 20500 or a variant, such as a functional equivalent, of either such nucleotide sequence. A nucleic acid molecule which is complementary to another nucleotide sequence is one which is sufficiently complementary to the other nucleotide sequence such that it can hybridize to the other nucleotide sequence thereby forming a stable duplex. The term "cDNA" (complementary DNA) is defined herein as a DNA molecule which can be prepared by reverse transcription from a mRNA molecule. In prokaryotes the mRNA molecule is obtained from the transcription of the genomic DNA of a gene present in a cell. In eukaryotic cells genes contain both exons, i.e. coding sequences, and introns, i.e. intervening sequences located between the exons. Therefore in eukaryotic cell the initial, primary RNA obtained from transcription of the genomic DNA of a gene is processed through a series of steps before appearing as mRNA. These steps include the removal of intron sequences by a process called splicing. cDNA derived from mRNA only contains coding sequences and can be directly translated into the corresponding polypeptide product. The term "complementary strand" can be used interchangeably with the term "complement". The complement of a nucleic acid strand can be the complement of a coding strand or the complement of a non-coding strand. When referring to double- stranded nucleic acids, the complement of a nucleic acid encoding a polypeptide refers to the complementary strand of the strand encoding the amino acid sequence or to any nucleic acid molecule containing the same.
As used herein, the term "hybridization" means the pairing of substantially complementary strands of oligomeric compounds. One mechanism of pairing involves hydrogen bonding, which may be Watson-Crick, Hoogsteen or reversed Hoogsteen hydrogen bonding, between complementary nucleotide bases (nucleotides) of the strands of oligomeric compounds. For example, adenine and thymine are complementary nucleic acids which pair through the formation of hydrogen bonds. Hybridization can occur under varying circumstances. "Stringency hybridization" or "hybridizes under low stringency, medium stringency, high stringency, or very high stringency conditions" is used herein to describe conditions for hybridization and washing, more specifically conditions under which an oligomeric compound will hybridize to its target sequence, but to a minimal number of other sequences. So, the oligomeric compound will hybridize to the target sequence to a detectably greater degree than to other sequences. Guidance for performing hybridization reactions can be found in Current Protocols in Molecular Biology, John Wiley & Sons, N.Y. (1989), 6.3.1 -6:3.6. Aqueous and non-aqueous methods are described in that reference and either can be used. Stringency conditions are sequence-dependent and will be different in different circumstances. Generally, stringency conditions are selected to be about 5°C lower than the thermal melting point (Tm) for the oligomeric compound at a defined ionic strength and pH. The Tm is the temperature (under defined ionic strength and pH) at which 50% of an oligomeric compound hybridizes to a perfectly matched probe. Stringency conditions may also be achieved with the addition of destabilizing agents such as formamide.
Examples of specific hybridization conditions are as follows: 1 ) low stringency hybridization conditions in 6X sodium chloride/sodium citrate (SSC) at about 45°C, followed by two washes in 0.2X SSC, 0.1 % SDS at least at 50°C (the temperature of the washes can be increased to 55°C for low stringency conditions); 2) medium stringency hybridization conditions in 6X SSC at about 45°C, followed by one or more washes in 0.2X SSC, 0.1 % SDS at 60°C; 3) high stringency hybridization conditions in 6X SSC at about 45°C, followed by one or more washes in 0.2X SSC, 0.1 % SDS at 65°C; and 4) very high stringency hybridization conditions are 0.5M sodium phosphate, 7% SDS at 65°C, followed by one or more washes at 0.2X SSC, 1 % SDS at 65°C.
In general, high stringency conditions, such as high hybridization temperature and optionally low salt concentrations, permit only hybridization between sequences that are highly similar, whereas low stringency conditions, such as low hybridization temperature and optionally high salt concentrations, allow hybridization when the sequences are less similar.
One aspect of the invention pertains to isolated nucleic acid molecules that encode a polypeptide of the invention or a variant, such as a functional equivalent thereof, for example a biologically active fragment or domain, as well as nucleic acid molecules sufficient for use as hybridization probes to identify nucleic acid molecules encoding a polypeptide of the invention and fragments of such nucleic acid molecules suitable for use as PCR primers for the amplification or mutation of nucleic acid molecules.
Moreover, an "isolated nucleic acid fragment" is a nucleic acid fragment that is not naturally occurring, for example recombinant, as a fragment and would not be found in the natural state.
The term "naturally-occurring" as used herein refers to processes, events, or things that occur in their relevant form in nature. By contrast, "not naturally-occurring" refers to processes, events, or things whose existence or form involves the hand of man. Generally, the term "naturally-occurring" with regard to polypeptides or nucleic acids can be used interchangeable with the term "wild-type" or "native". It refers to polypeptide or nucleic acids encoding a polypeptide, having an amino acid sequence or polynucleotide sequence, respectively, identical to that found in nature. Naturally occurring polypeptides include native polypeptides, such as those polypeptides naturally expressed or found in a particular host. Naturally occurring polynucleotides include native polynucleotides such as those polynucleotides naturally found in the genome of a particular host. Additionally, a sequence that is wild-type or naturally-occurring may refer to a sequence from which a variant or a synthetic sequence is derived.
As used herein, a "synthetic" molecule is produced by in vitro chemical or enzymatic synthesis. It includes, but is not limited to, variant nucleic acids made with optimal codon usage for host organisms of choice.
The term "recombinant" when used in reference to a cell, nucleic acid, protein or vector, indicates that the cell, nucleic acid, protein or vector, has been modified by the introduction of a heterologous nucleic acid or protein or the alteration of a native nucleic acid or protein, or that the cell is derived from a cell so modified. Thus, for example, recombinant cells express genes that are not found within the native (non-recombinant) form of the cell or express native genes that are otherwise abnormally expressed, under expressed or not expressed at all. The term "recombinant" is synonymous with
"genetically modified".
The term "isolated polypeptide" as used herein means a polypeptide that is removed from at least one component, e.g. other polypeptide material, with which it is naturally associated. Thus, an isolated polypeptide may contain at most 10%, at most 8%, more preferably at most 6%, more preferably at most 5%, more preferably at most 4%, more preferably at most 3%, even more preferably at most 2%, even more preferably at most 1 % and most preferably at most 0,5% as determined by SDS-PAGE of other polypeptide material with which it is natively associated. The isolated polypeptide may be free of any other impurities. The isolated polypeptide may be at least 50% pure, e.g., at least 60% pure, at least 70% pure, at least 75% pure, at least 80% pure, at least 85% pure, at least 80% pure, at least 90% pure, or at least 95% pure, 96%, 97%, 98%, 99%, 99.5%, 99.9% as determined by SDS-PAGE or any other analytical method suitable for this purpose and known to the person skilled in the art. An "isolated polynucleotide" or "isolated nucleic acid" is a polynucleotide removed from other polynucleotides with which it is naturally associated. Thus, an isolated polynucleotide may contain at most 10%, at most 8%, more preferably at most 6%, more preferably at most 5%, more preferably at most 4%, more preferably at most 3%, even more preferably at most 2%, even more preferably at most 1 % and most preferably at most 0,5% by weight of other polynucleotide material with which it is naturally associated. The isolated polynucleotide may be free of any other impurities. The isolated polynucleotide may be at least 50% pure, e.g., at least 60% pure, at least 70% pure, at least 75% pure, at least 80% pure, at least 85% pure, at least 90% pure, or at least 95%, 96%, 97%, 98%, 99%, 99.5%, 99.9% pure by weight.
The term "substantially pure" with regard to polypeptides refers to a polypeptide preparation which contains at the most 50% by weight of other polypeptide material. The polypeptides disclosed herein are preferably in a substantially pure form. In particular, it is preferred that the polypeptides disclosed herein are in "essentially pure form", i.e. that the polypeptide preparation is essentially free of other polypeptide material. Optionally, the polypeptide may also be essentially free of non-polypeptide material such as nucleic acids, lipids, media components, and the like. Herein, the term "substantially pure polypeptide" is synonymous with the terms "isolated polypeptide" and "polypeptide in isolated form". The term "substantially pure" with regard to polynucleotide refers to a polynucleotide preparation which contains at the most 50% by weight of other polynucleotide material. The polynucleotides disclosed herein are preferably in a substantially pure form. In particular, it is preferred that the polynucleotide disclosed herein are in "essentially pure form", i.e. that the polynucleotide preparation is essentially free of other polynucleotide material. Optionally, the polynucleotide may also be essentially free of non-polynucleotide material such as polypeptides, lipids, media components, and the like. Herein, the term "substantially pure polynucleotide" is synonymous with the terms "isolated polynucleotide" and "polynucleotide in isolated form".
The term "nucleic acid" as used in the present invention refers to a nucleotide polymer including at least 5 nucleotide units. A nucleic acid refers to a ribonucleotide polymer (RNA), deoxynucleotide polymer (DNA) or a modified form of either type of nucleic acid or synthetic form thereof or mixed polymers of any of the above. Nucleic acids may include either or both naturally-occurring and modified nucleic acids linked together by naturally-occurring and/or non-naturally occurring nucleic acid linkages. The nucleic acid molecules may be modified chemically or biochemically or may contain non- natural or derivatized nucleic acid bases, as will be readily appreciated by those of skill in the art. Such modifications include, for example, labels, methylation, substitution of one or more of the naturally occurring nucleic acids with an analog, internucleotide modifications such as uncharged linkages (e.g., methyl phosphonates, phosphotriesters, phosphoramidates, carbamates, etc.), charged linkages (e.g., phosphorothioates, phosphorodithioates, etc.), pendent moieties (e.g., polypeptides), intercalators (e.g., acridine, psoralen, etc.), chelators, alkylators, and modified linkages (e.g., alpha anomeric nucleic acids, etc.) The term nucleic acid is also intended to include any topological conformation, including single-stranded (sense strand and antisense strand), double-stranded, partially duplexed, triplex, hairpinned, circular and padlocked conformations. Also included are synthetic molecules that mimic nucleic acids in their ability to bind to a designated sequence via hydrogen bonding and other chemical interactions. Such molecules are known in the art and include, for example, those in which peptide linkages substitute for phosphate linkages in the backbone of the molecule. A reference to a nucleic acid sequence encompasses its complement unless otherwise specified. Thus, a reference to a nucleic acid molecule having a particular sequence should be understood to encompass its complementary strand, with its complementary sequence. The complementary strand is also useful, e.g., for antisense therapy, hybridization probes and PCR primers. The term "nucleic acid", "nucleic acid molecule" and "polynucleotide" can be used interchangeably herein.
A "substitution", as used herein in relation to polypeptides or nucleic acids, denotes the replacement of one or more amino acids in a polypeptide sequence or of one or more nucleotides in a polynucleotide sequence, respectively, by different amino acids or nucleotides, respectively
Another embodiment of the invention provides an isolated nucleic acid molecule which is antisense to a nucleic acid molecule encoding the polypeptide of the invention, e.g., the coding strand of a nucleic acid molecule encoding the protein of the invention. Also included within the scope of the invention are the complementary strands of the nucleic acid molecules described herein.
Unless otherwise indicated, all nucleotide sequences determined by sequencing a DNA molecule herein were determined using an automated DNA sequencer and all amino acid sequences of polypeptides encoded by DNA molecules determined herein were predicted by translation of a DNA sequence determined as above. Therefore, as is known in the art for any DNA sequence determined by this automated approach, any nucleotide sequence determined herein may contain some errors. Nucleotide sequences determined by automation are typically at least about 90% identical, more typically at least about 95% to at least about 99.9% identical to the actual nucleotide sequence of the sequenced DNA molecule.
The actual sequence can be more precisely determined by other approaches including manual DNA sequencing methods well known in the art. As is also known in the art, a single insertion or deletion in a determined nucleotide sequence compared to the actual sequence will cause a frame shift in translation of the nucleotide sequence such that the predicted amino acid sequence encoded by a determined nucleotide sequence will be completely different from the amino acid sequence actually encoded by the sequenced DNA molecule, beginning at the point of such an insertion or deletion. The term "deletion", as used herein, denotes a change in either amino acid or nucleic acid sequence in which one or more amino acid or nucleotide, respectively, are absent as compared to the parent, often the naturally occurring, amino acid or nucleic acid sequence. The term "insertion", also known as the term "addition", denotes a change in an amino acid or nucleic acid sequence resulting in the addition of one or more amino acid or nucleotide, respectively, as compared to the parent, often the naturally occurring, amino acid or nucleic acid sequence.
The person skilled in the art is capable of identifying such erroneously identified bases and knows how to correct for such errors for example by sequencing the relevant gene of TEC-101 or the genome of TEC-101 (CBS 127450) as described in WO201 1/000949. A nucleic acid molecule according to the invention may comprise only a portion or a fragment of the nucleic acid sequence shown in SEQ ID NO: 1 to 20500 (or of a variant of either thereof), for example a fragment which can be used as a probe or primer or a fragment encoding a portion of a protein of the invention.
The nucleotide sequence determined from the cloning of gene encoding the protein of the invention and cDNA allows for the generation of probes and primers designed for use in identifying and/or cloning other family members of the protein of the invention, as well as homologues from other species.
The probe/primer typically comprises a substantially purified oligonucleotide which typically comprises a region of nucleotide sequence that hybridizes preferably under highly stringent conditions to at least from about 12 to about 15, preferably from about 18 to about 20, preferably from about 22 to about 25, more preferably about 30, about 35, about 40, about 45, about 50, about 55, about 60, about 65, or about 75 or more consecutive nucleotides of a nucleotide sequence shown in SEQ ID NO: 1 to 20500 or of a variant, such as a functional equivalent, of either thereof. Probes based on nucleotide sequences encoding the protein of the invention can be used to detect transcripts or genomic sequences corresponding to the protein of the invention encoding the same or homologous proteins for instance in other organisms. In preferred embodiments, the probe further comprises a label group attached thereto, e.g., the label group can be a radioisotope, a fluorescent compound, an enzyme, or an enzyme cofactor. Such probes can also be used as part of a diagnostic test kit for identifying cells which express a protein of the invention.
The polynucleotides herein may be synthetic polynucleotides. The synthetic polynucleotides may be optimized in codon use, preferably according to the methods described in WO2006/077258 and/or PCT/EP2007/055943, which are herein incorporated by reference. PCT/EP2007/055943 addresses codon-pair optimization. Codon-pair optimization is a method wherein the nucleotide sequences encoding a polypeptide have been modified with respect to their codon-usage, in particular the codon-pairs that are used, to obtain improved expression of the nucleotide sequence encoding the polypeptide and/or improved production of the encoded polypeptide. Codon pairs are defined as a set of two subsequent triplets (codons) in a coding sequence. Those skilled in the art will know that the codon usage needs to be adapted depending on the host species, possibly resulting in variants with significant homology deviation from SEQ ID NO: 1 or 20500 but still encoding the polypeptide of the invention.
The term "expression" includes any step involved in the production of the polypeptide including, but not limited to, transcription, post transcriptional modification, translation, post-translational modification, and secretion.
The invention further relates to a nucleic acid construct comprising the polynucleotide as described before. The term "nucleic acid construct" is herein referred to as a nucleic acid molecule, either single- or double-stranded, which is isolated from a naturally occurring gene or which has been modified to contain segments of nucleic acid which are combined and juxtaposed in a manner which would not otherwise exist in nature. The term nucleic acid construct is synonymous with the term "expression cassette" when the nucleic acid construct contains all the control sequences required for expression of a coding sequence, wherein said control sequences are operably linked to said coding sequence.
The term "coding sequence" as defined herein is a sequence, which is transcribed into mRNA and translated into a transcriptional activator of a protease promoter of the invention. The boundaries of the coding sequence are generally determined by the ATG start codon at the 5'end of the mRNA and a translation stop codon sequence terminating the open reading frame at the 3' end of the mRNA. A coding sequence can include, but is not limited to, DNA, cDNA, and recombinant nucleic acid sequences. Preferably, the nucleic acid has high GC content. The GC content herein indicates the number of G and C nucleotides in the construct, divided by the total number of nucleotides, expressed in %. The GC content is preferably 56% or more, 57% or more, 58% or more, 59% or more, 60% or more, or in the range of 56-70% or the range of 58-65%. Preferably, the DNA construct comprises a promoter DNA sequence, a coding sequence in operative association with said promoter DNA sequence and control sequences such as:- one translational termination sequence orientated in 5' towards 3' direction selected from the following list of sequences: TAAG, TAGA and TAAA, preferably TAAA, and/or- one translational initiator coding sequence orientated in 5' towards 3' direction selected from the following list of sequences: GCTACCCCC; GCTACCTCC; GCTACCCTC; GCTACCTTC; GCTCCCCCC; GCTCCCTCC; GCTCCCCTC; GCTCCCTTC; GCTGCCCCC; GCTGCCTCC; GCTGCCCTC; GCTGCCTTC; GCTTCCCCC; GCTTCCTCC; GCTTCCCTC; and GCTTCCTTC, preferably GCT TCC TTC, and/or
one translational initiator sequence selected from the following list of sequences: 5'-mwChkyCAAA-3'; 5'-mwChkyCACA-3' or 5'-mwChkyCAAG-3', using ambiguity codes for nucleotides: m (A/C); w (A/T); y (C/T); k (G/T); h (A/C/T), preferably 5'-CACCGTCAAA-3' or 5'-CGCAGTCAAG-3'.
In the context of this invention, the term "translational initiator coding sequence" is defined as the nine nucleotides immediately downstream of the initiator or start codon of the open reading frame of a DNA coding sequence. The initiator or start codon encodes for the AA methionine. The initiator codon is typically ATG, but may also be any functional start codon such as GTG.
In the context of this invention, the term "translational termination sequence" is defined as the four nucleotides starting from the translational stop codon at the 3' end of the open reading frame or nucleotide coding sequence and oriented in 5' towards 3' direction.
In the context of this invention, the term "translational initiator sequence" is defined as the ten nucleotides immediately upstream of the initiator or start codon of the open reading frame of a DNA sequence coding for a polypeptide. The initiator or start codon encodes for the AA methionine. The initiator codon is typically ATG, but may also be any functional start codon such as GTG. It is well known in the art that uracil, U, replaces the deoxynucleotide thymine, T, in RNA.
Homology and identity
The terms "sequence homology" or "sequence identity" are used interchangeably herein. For the purpose of this invention, it is defined here that in order to determine the percentage of sequence homology or sequence identity of two amino acid sequences or of two nucleic acid sequences, the sequences are aligned for optimal comparison purposes. In order to optimize the alignment between the two sequences gaps may be introduced in any of the two sequences that are compared. Such alignment can be carried out over the full length of the sequences being compared. Alternatively, the alignment may be carried out over a shorter length, for example over about 20, about 50, about 100 or more nucleic acids/based or amino acids. The sequence identity is the percentage of identical matches between the two sequences over the reported aligned region.
A comparison of sequences and determination of percentage of sequence identity between two sequences can be accomplished using a mathematical algorithm. The skilled person will be aware of the fact that several different computer programs are available to align two sequences and determine the identity between two sequences (Kruskal, J. B. (1983) An overview of sequence comparison In D. Sankoff and J. B. Kruskal, (ed.), Time warps, string edits and macromolecules: the theory and practice of sequence comparison, pp. 1 -44 Addison Wesley). The percent sequence identity between two amino acid sequences or between two nucleotide sequences may be determined using the Needleman and Wunsch algorithm for the alignment of two sequences. (Needleman, S. B. and Wunsch, C. D. (1970) J. Mol. Biol. 48, 443-453). Both amino acid sequences and nucleotide sequences can be aligned by the algorithm. The Needleman-Wunsch algorithm has been implemented in the computer program NEEDLE. For the purpose of this invention the NEEDLE program from the EMBOSS package was used (version 2.8.0 or higher, EMBOSS: The European Molecular Biology Open Software Suite (2000) Rice, P. LongdenJ. and BleasbyA Trends in Genetics 16, (6) pp276— 277, http://emboss.bioinformatics.nl/). For protein sequences EBLOSUM62 is used for the substitution matrix. For nucleotide sequence, EDNAFULL is used. The optional parameters used are a gap-open penalty of 10 and a gap extension penalty of 0.5. The skilled person will appreciate that all these different parameters will yield slightly different results but that the overall percentage identity of two sequences is not significantly altered when using different algorithms.
After alignment by the program NEEDLE as described above the percentage of sequence identity between a query sequence and a sequence of the invention is calculated as follows: Number of corresponding positions in the alignment showing an identical amino acid or identical nucleotide in both sequences divided by the total length of the alignment after subtraction of the total number of gaps in the alignment. The identity defined as herein can be obtained from NEEDLE by using the NOBRIEF option and is labeled in the output of the program as "longest-identity".
The nucleic acid and protein sequences of the present invention can further be used as a "query sequence" to perform a search against public databases to, for example, identify other family members or related sequences. Such searches can be performed using the NBLAST and XBLAST programs (version 2.0) of Altschul, et al. (1990) J. Mol. Biol. 215:403—10. BLAST nucleotide searches can be performed with the NBLAST program, score = 100, wordlength = 12 to obtain nucleotide sequences homologous to nucleic acid molecules of the invention. BLAST protein searches can be performed with the XBLAST program, score = 50, wordlength = 3 to obtain amino acid sequences homologous to protein molecules of the invention. To obtain gapped alignments for comparison purposes, Gapped BLAST can be utilized as described in Altschul et al., (1997) Nucleic Acids Res. 25(17): 3389-3402. When utilizing BLAST and Gapped BLAST programs, the default parameters of the respective programs (e.g., XBLAST and NBLAST) can be used. See the homepage of the National Center for Biotechnology Information at http://www.ncbi.nlm.nih.gov/.
Vectors
An expression vector comprises a polynucleotide coding for a polypeptide, operably linked to the appropriate control sequences (such as a promoter, and transcriptional and translational stop signals) for expression and/or translation in vitro, or in the host cell of the polynucleotide. Certain vectors are capable of directing the expression of genes to which they are operatively linked. Such vectors are referred to herein as "expression vectors". In general, expression vectors of utility in recombinant DNA techniques are often in the form of plasmids.
The expression vector may be any vector (e.g., a plasmid or virus), which can be conveniently subjected to recombinant DNA procedures and can bring about the expression of the polynucleotide. The choice of the vector will typically depend on the compatibility of the vector with the cell into which the vector is to be introduced. The vectors may be linear or closed circular plasmids. The vector may be an autonomously replicating vector, i. e., a vector, which exists as an extra-chromosomal entity, the replication of which is independent of chromosomal replication, e.g., a plasmid, an extra- chromosomal element, a mini-chromosome, or an artificial chromosome. Alternatively, the vector may be one which, when introduced into the host cell, is integrated into the genome and replicated together with the chromosome(s) into which it has been integrated. The integrative cloning vector may integrate at random or at a predetermined target locus in the chromosomes of the host cell.
The vector system may be a single vector or plasmid or two or more vectors or plasmids, which together contain the total DNA to be introduced into the genome of the host cell, or a transposon.
The vectors preferably contain one or more selectable markers, which permit easy selection of transformed cells.
Another aspect of the invention pertains to vectors, including cloning and expression vectors, comprising a polynucleotide of the invention encoding a protein of the invention or a functional equivalent thereof and methods of growing, transforming or transfecting such vectors in a suitable host cell, for example under conditions in which expression of a polypeptide of the invention occurs. As used herein, the term "vector" refers to a nucleic acid molecule capable of transporting another nucleic acid to which it has been linked. Thus in a further embodiment, the invention provides a method of making polynucleotides of the invention by introducing a polynucleotide of the invention into a replicable vector, introducing the vector into a compatible host cell, and growing the host cell under conditions which bring about replication of the vector. The vector may be recovered from the host cell. Suitable host cells are described below.
One type of vector is a "plasmid", which refers to a circular double stranded DNA loop into which additional DNA segments can be ligated. Another type of vector is a viral vector, wherein additional DNA segments can be ligated into the viral genome. The terms "plasmid" and "vector" can be used interchangeably herein as the plasmid is the most commonly used form of vector. However, the invention is intended to include such other forms of expression vectors, such as cosmid, viral vectors (e.g., replication defective retroviruses, adenoviruses and adeno-associated viruses) and phage vectors which serve equivalent functions. Vectors according to the invention may be used in vitro, for example for the production of RNA or used to transfect or transform a host cell.
A vector of the invention may comprise two or more, for example three, four or five, polynucleotides of the invention, for example for overexpression.
The recombinant expression vectors of the invention comprise a nucleic acid of the invention in a form suitable for expression of the nucleic acid in a host cell, which means that the recombinant expression vector includes one or more regulatory sequences, selected on the basis of the host cells to be used for expression, which is operably linked to the nucleic acid sequence to be expressed.
The term "operably linked", "operatively linked" or "in operative association" as used herein refers to two or more nucleic acid sequence elements that are physically linked and are in a functional relationship with each other. For instance, a promoter is operably linked to a coding sequence if the promoter is able to initiate or regulate the transcription or expression of a coding sequence, in which case the coding sequence should be understood as being "under the control of" the promoter. Generally, when two nucleic acid sequences are operably linked, they will be in the same orientation and usually also in the same reading frame. They usually will be essentially contiguous, although this may not be required.
A vector or expression construct for a given host cell may thus comprise the following elements operably linked to each other in a consecutive order from the 5'-end to 3'-end relative to the coding strand of the sequence encoding the polypeptide of the first invention: (1 ) a promoter sequence capable of directing transcription of the nucleotide sequence encoding the polypeptide in the given host cell ; (2) optionally, a signal sequence capable of directing secretion of the polypeptide from the given host cell into a culture medium; (3) a DNA sequence of the invention encoding a mature and preferably active form of a polypeptide having preferably biological activity; and preferably also (4) a transcription termination region (terminator) capable of terminating transcription downstream of the nucleotide sequence encoding the polypeptide.
The term "mature polypeptide" or "mature form of a polypeptide" is defined herein as a polypeptide in its final form and is obtained after translation of a mRNA into polypeptide and post-translational modifications of said polypeptide. Post-translational modification include N-terminal processing, C-terminal truncation, glycosylation, phosphorylation and removal of leader sequences such as signal peptides, pro-peptides and/or prepro-peptides as defined herein by cleavage. Downstream of the nucleotide sequence according to the invention there may be a 3' untranslated region containing one or more transcription termination sites (e. g. a terminator). The terminator can, for example, be native to the DNA sequence encoding the polypeptide. However, preferably a yeast terminator is used in yeast host cells and a filamentous fungal terminator is used in filamentous fungal host cells. More preferably, the terminator is endogenous to the host cell (in which the nucleotide sequence encoding the polypeptide is to be expressed). In the transcribed region, a ribosome binding site for translation may be present. The coding portion of the mature transcripts expressed by the constructs will include a translation initiating AUG at the beginning and a termination codon appropriately positioned at the end of the polypeptide to be translated.
Enhanced expression of the polynucleotide of the invention may also be achieved by the selection of heterologous regulatory regions, e. g. promoter, secretion leader and/or terminator regions, which may serve to increase expression and, if desired, secretion levels of the protein of interest from the expression host and/or to provide for the inducible control of the expression of a polypeptide of the invention.
It will be appreciated by those skilled in the art that the design of the expression vector can depend on such factors as the choice of the host cell to be transformed, the level of expression of protein desired, etc. The vectors, such as expression vectors, of the invention can be introduced into host cells to thereby produce proteins or polypeptides, encoded by nucleic acids as described herein (e.g. proteins of the invention, mutant forms of proteins of the invention, fragments, variants or functional equivalents thereof. The vectors, such as recombinant expression vectors, of the invention can be designed for expression of proteins of the invention in prokaryotic or eukaryotic cells.
For example, proteins of the invention can be expressed in bacterial cells such as E. coli, insect cells (using baculovirus expression vectors), filamentous fungi, yeast cells or mammalian cells. Suitable host cells are discussed further in Goeddel, Gene Expression Technology: Methods in Enzymology 185, Academic Press, San Diego, CA (1990). Representative examples of appropriate hosts are described hereafter.
Appropriate culture mediums and conditions for the above-described host cells are known in the art.
The recombinant expression vector can be transcribed and translated in vitro, for example using T7 promoter regulatory sequences and T7 polymerase. For most filamentous fungi and yeast, the vector or expression construct is preferably integrated in the genome of the host cell in order to obtain stable transformants. However, for certain yeasts also suitable episomal vectors are available into which the expression construct can be incorporated for stable and high level expression, examples thereof include vectors derived from the 2μ and pKD1 plasmids of Saccharomyces and Kluyveromyces, respectively, or vectors containing an AMA sequence (e.g. AMA1 from Aspergillus). In case the expression constructs are integrated in the host cells genome, the constructs are either integrated at random loci in the genome, or at predetermined target loci using homologous recombination, in which case the target loci preferably comprise a highly expressed gene.
Accordingly, expression vectors useful in the present invention include chromosomal-, episomal- and virus-derived vectors e.g., vectors derived from bacterial plasmids, bacteriophage, yeast episome, yeast chromosomal elements, viruses such as baculoviruses, papova viruses, vaccinia viruses, adenoviruses, fowl pox viruses, pseudorabies viruses and retroviruses, and vectors derived from combinations thereof, such as those derived from plasmid and bacteriophage genetic elements, such as cosmids and phagemids.
The term "control sequence", "regulatory element" or "regulatory sequence" can be used interchangeably with the term "expression-regulating nucleic acid sequence". The term as used herein refers to nucleic acid sequences necessary for and/or affecting the expression of an operably linked coding sequence in a particular host organism or in vitro. When two nucleic acid sequences are operably linked, they usually will be in the same orientation and also in the same reading frame. They usually will be essentially contiguous, although this may not be required. The expression-regulating nucleic acid sequences, such as inter alia appropriate transcription initiation, termination, promoter, leader, signal peptide, pro-peptide, prepro-peptide, or enhancer sequences; Shine- Delgarno sequence, repressor or activator sequences; efficient RNA processing signals such as splicing and polyadenylation signals; sequences that stabilize cytoplasmic mRNA; sequences that enhance translation efficiency (e.g., ribosome binding sites); sequences that enhance protein stability; and when desired, sequences that enhance protein secretion, can be any nucleic acid sequence showing activity in the host organism of choice and can be derived from genes encoding proteins, which are either homologous or heterologous to the host organism. Each control sequence may be native or foreign to the nucleic acid sequence encoding the polypeptide. When desired, the control sequence may be provided with linkers for the purpose of introducing specific restriction sites facilitating ligation of the control sequences with the coding region of the nucleic acid sequence encoding a polypeptide. Control sequences may be optimized to their specific purpose.
The control sequence may be an appropriate promoter sequence, a nucleic acid sequence, which is recognized by a host cell for expression of the nucleic acid sequence. The promoter sequence contains transcriptional control sequences, which mediate the expression of the polypeptide. The promoter may be any nucleic acid sequence, which shows transcriptional activity in the cell including mutant, truncated, and hybrid promoters, and may be obtained from genes encoding extracellular or intracellular polypeptides either homologous or heterologous to the cell.
The term "promoter" is defined herein as a DNA sequence that binds RNA polymerase and directs the polymerase to the correct downstream transcriptional start site of a nucleic acid sequence encoding a biological compound to initiate transcription. RNA polymerase effectively catalyzes the assembly of messenger RNA complementary to the appropriate DNA strand of a coding region. The term "promoter" will also be understood to include the 5'-non-coding region (between promoter and translation start) for translation after transcription into mRNA, cis-acting transcription control elements such as enhancers, and other nucleotide sequences capable of interacting with transcription factors. The promoter may be any appropriate promoter sequence suitable for a eukaryotic or prokaryotic host cell, which shows transcriptional activity, including mutant, truncated, and hybrid promoters, and may be obtained from polynucleotides encoding extra-cellular or intracellular polypeptides either homologous (native) or heterologous (foreign) to the cell. The promoter may be a constitutive or inducible promoter.
Preferably the promoter is an inducible promoter. More preferably the promoter is a carbohydrate inducible promoter. Carbohydrate inducible promoters that are preferably used are selected from a starch-inducible promoter (i.e. a promoter inducible by starch, a monomer, a dimer, a oligomer thereof, such as for example a maltose-inducible promoter, an isomaltose-inducible promoter), a cellulose-inducible promoter (i.e. a promoter inducible by cellulose, a monomer, a dimer and/or oligomer thereof, such as for example a cellobiose-inducible promoter, a sophorose-inducible promoter), a hemicellulose inducible promoter (i.e. a promoter inducible by hemicellulose, a monomer, a dimer, and/or a oligomer thereof, such as e.g. a xylan-inducible promoter, an arabionose-inducible promoter, a xylose-inducible promoter), a pectin-inducible promoter (i.e. a promoter inducible by pectin, a monomer, a dimer and/or an oligomer thereof such as for example a galacturonic acid-inducible promoter, a rhamnose- inducible promoter), an arabinan-inducible promoter (i.e. a promoter inducible by arabinan, a monomer, a dimer, and/or an oligomer thereof such as for example an arabinose-inducible promoter), a glucose-inducible promoter, a lactose-inducible promoter, a galactose-inducible promoter. Other inducible promoters are copper-, oleic acid- inducible promoters.
Promoters suitable in filamentous fungi are promoters which may be selected from the group, which includes but is not limited to promoters obtained from the polynucleotides encoding A. oryzae TAKA amylase, Rhizomucor miehei aspartic proteinase, Aspergillus gpdA promoter, A. niger neutral alpha-amylase, A. niger acid stable alpha-amylase, A. niger or A. awamori glucoamylase (glaA), A. niger or A. awamori endoxylanase (xlnA) or beta-xylosidase (x/nD), T. reesei cellobiohydrolase I (CBHI), R. miehei lipase, A. oryzae alkaline protease, A. oryzae triose phosphate isomerase, A. nidulans acetamidase, Fusarium venenatum amyloglucosidase (WO 00/56900), Fusarium venenatum Dania (WO 00/56900), Fusarium venenatum Quinn (WO 00/56900), Fusarium oxysporum trypsin-like protease (WO 96/00787), Trichoderma reesei beta-glucosidase, Trichoderma reesei cellobiohydrolase I, Trichoderma reesei cellobiohydrolase II, Trichoderma reesei endoglucanase I, Trichoderma reesei endoglucanase II, Trichoderma reesei endoglucanase III, Trichoderma reesei endoglucanase IV, Trichoderma reesei endoglucanase V, Trichoderma reesei xylanase I, Trichoderma reesei xylanase II, Trichoderma reesei beta-xylosidase, as well as the NA2-tpi promoter (a hybrid of the promoters from the polynucleotides encoding A. niger neutral alpha-amylase and A. oryzae triose phosphate isomerase), and mutant, truncated, and hybrid promoters thereof. Other examples of promoters are the promoters described in WO2006/092396 and WO2005/100573, which are herein incorporated by reference. Even other examples of the use of promoters are described in WO2008/098933 and co-pending patent application no. EP12172605. Preferred carbohydrate inducible promoters which can be used in filamentous fungi are Rasamsonia promoters such Rasamsonia emersonii beta-glucosidase, Rasamsonia emersonii cellobiohydrolase I, Rasamsonia emersonii cellobiohydrolase II, Rasamsonia emersonii endoglucanase IV(GH61 ), Rasamsonia emersonii acetyl xylan esterase promoter, A. oryzae TAKA amylase, A. niger neutral alpha-amylase, A. niger acid stable alpha-amylase, A. niger or A. awamori glucoamylase (glaA), A. niger or A. awamori endoxylanase (xlnA) or beta-xylosidase (x/nD), T, Trichoderma reesei beta-glucosidase, Trichoderma reesei cellobiohydrolase I, Trichoderma reesei cellobiohydrolase II, Trichoderma reesei endoglucanase I, Trichoderma reesei endoglucanase II, Trichoderma reesei endoglucanase III, Trichoderma reesei endoglucanase IV, Trichoderma reesei endoglucanase V, Trichoderma reesei xylanase I, Trichoderma reesei xylanase II, Trichoderma reesei beta-xylosidase, as well as the NA2-tpi promoter (a hybrid of the promoters from the polynucleotides encoding A. niger neutral alpha- amylase and A. oryzae triose phosphate isomerase) as defined above.
Also promoters disclosed in WO2009150195 can be used, these promoters direct expression in a wide range of industrially relevant species, both prokaryotes and eukaryotes. When the polynucleotide sequences of the invention are applied in combination with selection marker genes it is possible to perform selectable cloning in a laboratory host and use the same construct in the final host.
Examples of such promoters from Gram-positive microorganisms include, but are not limited to gnt (gluconate operon promoter); penP from Bacillus licheniformis; glnA (glutamine synthetase); xylAB (xylose operon); araABD (L-arabinose operon) and Pspac promoter, a hybrid SP01/lac promoter that can be controlled by inducers such as isopropyl^-D-thiogalactopyranoside [IPTG] ((Yansura D.G., Henner D.J. Proc Natl Acad Sci U S A. 1984 81 (2):439-443). Activators are also sequence-specific DNA binding proteins that induce promoter activity. Examples of such promoters from Gram-positive microorganisms include, but are not limited to, two-component systems (PhoP-PhoR, DegU-DegS, SpoOA-Phosphorelay), LevR, Mry and GltC. (ii) Production of secondary sigma factors can be primarily responsible for the transcription from specific promoters. Examples from Gram-positive microorganisms include, but are not limited to, the promoters activated by sporulation specific sigma factors: aF, σΕ, aG and σΚ and general stress sigma factor, σΒ. The σΒ-mediated response is induced by energy limitation and environmental stresses (Hecker M, Volker U. Mol Microbiol. 1998; 29(5):1 129-1 136.). (iii) Attenuation and antitermination also regulates transcription. Examples from Gram-positive microorganisms include, but are not limited to, trp operon and sacB gene, (iv) Other regulated promoters in expression vectors are based the sacR regulatory system conferring sucrose inducibility (Klier AF, Rapoport G. Annu Rev Microbiol. 1988;42:65-95). Suitable inducible promoters useful in bacteria, such as Bacilli, include: promoters from Gram-positive microorganisms such as, but are not limited to, SP01 -26, SP01 -15, veg, pyc (pyruvate carboxylase promoter), and amyE. Examples of promoters from Gram-negative microorganisms include, but are not limited to, tac, tet, trp-tet, Ipp, lac, Ipp-lac, laclq, T7, T5, T3, gal, trc, ara, SP6, λ-PR, and λ-PL.
Additional examples of promoters useful in bacterial cells, such as Bacilli, include the a-amylase and SPo2 promoters as well as promoters from extracellular protease genes.
Another example of a suitable promoter is the promoter obtained from the E. coli lac operon. Another example is the promoter of the Streptomyces coelicolor agarase gene (dagA). Another example is the promoter of the Bacillus lentus alkaline protease gene (aprH). Another example is the promoter of the Bacillus licheniformis alkaline protease gene (subtilisin Carlsberg gene). Another example is the promoter of the Bacillus subtilis levansucrase gene (sacB). Another example is the promoter of the Bacillus subtilis alphaamylase gene (amyF). Another example is the promoter of the Bacillus licheniformis alphaamylase gene (amyL). Another example is the promoter of the Bacillus stearothermophilus maltogenic amylase gene (amyM). Another example is the promoter of the Bacillus amyloliquefaciens alpha-amylase gene (amyQ). Another example is a "consensus" promoter having the sequence TTGACA for the "-35" region and TATAAT for the "-10" region. Another example is the promoter of the Bacillus licheniformis penicillinase gene (penP). Another example are the promoters of the Bacillus subtilis xylA and xylB genes.
Preferably the promoter sequence is from a highly expressed gene. Examples of preferred highly expressed genes from which promoters may be selected and/or which are comprised in preferred predetermined target loci for integration of expression constructs, include but are not limited to genes encoding glycolytic enzymes such as triose-phosphate isomerases (TPI),glyceraldehyde-phosphate dehydrogenases (GAPDH), phosphoglycerate kinases (PGK), pyruvate kinases (PYK or PKI), alcohol dehydrogenases (ADH), as well as genes encoding amylases, glucoamylases, proteases, xylanases, cellobiohydrolases, β-galactosidases, alcohol (methanol) oxidases, elongation factors and ribosomal proteins. Specific examples of suitable highly expressed genes include e. g. the LAC4 gene from Kluyveromyces sp., the methanol oxidase genes (AOX and MOX) from Hansenula and Pichia, respectively, the glucoamylase (glaA) genes from A. niger and A. awamori, the A. oryzae TAKA-amylase gene, the A. nidulans gpdA gene and the T. reesei cellobiohydrolase genes.
Promoters which can be used in yeast include e.g. promoters from glycolytic genes, such as the phosphofructokinase (PFK), triose phosphate isomerase (TPI), glyceraldehyde-3 -phosphate dehydrogenase (GPD, TDH3 or GAPDH), pyruvate kinase (PYK), phosphoglycerate kinase (PGK) promoters from yeasts or filamentous fungi; more details about such promoters from yeast may be found in (WO 93/03159). Other useful promoters are ribosomal protein encoding gene promoters, the lactase gene promoter (LAC4), alcohol dehydrogenase promoters (ADHI, ADH4, and the like), and the enolase promoter (ENO). Other promoters, both constitutive and inducible, and enhancers or upstream activating sequences will be known to those of skill in the art. The promoters used in the host cells of the invention may be modified, if desired, to affect their control characteristics. Suitable promoters in this context include both constitutive and inducible natural promoters as well as engineered promoters, which are well known to the person skilled in the art. Suitable promoters in eukaryotic host cells may be GAL7, GAL10, or GAL1, CYC1, HIS3, ADH1, PGL, PH05, GAPDH, ADC1, TRP1, URA3, LEU2, EN01, TPI1, and AOX1. Other suitable promoters include PDC1, GPD1, PGK1, TEF1, and TDH3. Examples of carbohydrate inducible promoters which can be used are GAL promoters, such as GAL1 or GAL10 promoters.
All of the above-mentioned promoters are readily available in the art.
Transcription of the DNA encoding the polypeptides of the present invention by higher eukaryotes may be increased by inserting an enhancer sequence into the vector. Enhancers are cis-acting elements of DNA, usually about from 10 to 300 bp that act to increase transcriptional activity of a promoter in a given host cell-type. Examples of enhancers include the SV40 enhancer, which is located on the late side of the replication origin at bp 100 to 270, the cytomegalovirus early promoter enhancer, the polyoma enhancer on the late side of the replication origin, and adenovirus enhancers.
The control sequence may also be a suitable transcription terminator sequence, a sequence recognized by a filamentous fungal cell to terminate transcription. The terminator sequence is operably linked to the 3' terminus of the nucleic acid sequence encoding the polypeptide. Any terminator, which is functional in the cell, may be used in the present invention.
The control sequence may also be a terminator. Preferred terminators for filamentous fungal cells are obtained from the genes encoding A. oryzae TAKA amylase, A. niger glucoamylase (glaA), A. nidulans anthranilate synthase, A. niger alpha- glucosidase, trpC gene and Fusarium oxysporum trypsin-like protease.
The control sequence may also include a suitable leader sequence, a non- translated region of a mRNA which is important for translation by the filamentous fungal cell. The leader sequence is operably linked to the 5' terminus of the nucleic acid sequence encoding the polypeptide. Any leader sequence, which is functional in the cell, may be used in the present invention. Preferred leaders for filamentous fungal cells are obtained from the genes encoding A. oryzae TAKA amylase and A. nidulans triose phosphate isomerase and A. niger glaA. Other preferred sequences are isolated and/or disclosed in WO2006/077258.
Other control sequences may be isolated from the Penicillium IPNS gene, or pcbC gene, the beta tubulin gene. All the control sequences cited in WO 01/21779 are herewith incorporated by reference.
The control sequence may also be a polyadenylation sequence, a sequence which is operably linked to the 3' terminus of the nucleic acid sequence and which, when transcribed, is recognized by the filamentous fungal cell as a signal to add polyadenosine residues to transcribed mRNA. Any polyadenylation sequence, which is functional in the cell, may be used in the present invention. Preferred polyadenylation sequences for filamentous fungal cells are obtained from the genes encoding A. oryzae TAKA amylase, A. niger glucoamylase, A. nidulans anthranilate synthase, Fusarium oxysporum trypsin-like protease and A. niger alpha-glucosidase.
When the polypeptide according to the invention is to be secreted from the host cell into the cultivation medium, an appropriate signal sequence can be added to the polypeptide in order to direct the de novo synthesized polypeptide to the secretion route of the host cell. The person skilled in the art knows to select an appropriate signal sequence for a specific host. The signal sequence may be native to the host cell, or may be foreign to the host cell. As an example, a signal sequence from a protein native to the host cell can be used. Preferably, said native protein is a highly secreted protein, i.e. a protein that is secreted in amounts higher than 10% of the total amount of protein being secreted. The signal sequences preferably used according to the invention are for example: pmeA.
As an alternative for a signal sequence, the polypeptide of the invention can be fused to a secreted carrier protein, or part thereof. Such chimeric construct is directed to the secretion route by means of the signal sequence of the carrier protein, or part thereof. In addition, the carrier protein will provide a stabilizing effect to the polypeptide according to the invention and or may enhance solubility. Such carrier protein may be any protein. Preferably, a highly secreted protein is used as a carrier protein. The carrier protein may be native or foreign to the polypeptide according to the invention. The carrier protein may be native of may be foreign to the host cell. Examples of such carrier proteins are glucoamylase, prepro sequence of alpha-Mating factor, cellulose binding domain of Clostridium cellulovorans cellulose binding protein A, glutathione S- transferase, chitin binding domain of Bacillus circulans chitinase A1 , maltose binding domain encoded by the malE gene of E. coli K12, beta-galactosidase, and alkaline phosphatase. A preferred carrier protein for expression of such chimeric construct in Aspergillus cells is glucoamylase. The carrier protein and polypeptide according to the invention may contain a specific amino acid motif to facilitate isolation of the polypeptide; the polypeptide according to the invention may be released by a special releasing agent. The releasing agent may be a proteolytic enzyme or a chemical agent. An example of such amino acid motif is the KEX protease cleavage site, which is well-known to the person skilled in the art.
A signal sequence can be used to facilitate secretion and isolation of a protein or polypeptide of the invention. Signal sequences are typically characterized by a core of hydrophobic amino acids, which are generally cleaved from the mature protein during secretion in one or more cleavage events. Such signal peptides contain processing sites that allow cleavage of the signal sequence from the mature proteins as they pass through the secretory pathway. The signal sequence directs secretion of the protein, such as from a eukaryotic host into which the expression vector is transformed, and the signal sequence is subsequently or concurrently cleaved. The protein can then be readily purified from the extracellular medium by known methods.
As an alternative for a signal sequence, the polypeptide of the invention can be fused to a secreted carrier protein, or part thereof. Such chimeric construct is directed to the secretion route by means of the signal sequence of the carrier protein, or part thereof. In addition, the carrier protein will provide a stabilizing effect to the polypeptide according to the invention and or may enhance solubility. Such carrier protein may be any protein. Preferably, a highly secreted protein is used as a carrier protein. The carrier protein may be native or foreign to the polypeptide according to the invention. The carrier protein may be native of may be foreign to the host cell. Examples of such carrier proteins are glucoamylase, prepro sequence of alpha-Mating factor, cellulose binding domain of Clostridium cellulovorans, cellulose binding protein A, glutathione S- transferase, chitin binding domain of Bacillus circulans chitinase A1 , maltose binding domain encoded by the malE gene of E. coli K12, beta-galactosidase, and alkaline phosphatase. A preferred carrier protein for expression of such chimeric construct in Aspergillus cells is glucoamylase.
As an alternative for secretion of the polypetide of the invention into the medium, the protein of the invention can be fused to a localisation sequence to target the protein of the invention to a desired cellular compartment, organel of a cell, or membrane. Such sequences are known to the person skilled in the art and include organel targeting sequences, such as peroxisomal transit sequences, nuclear localization sequences, endoplasmic reticulum retention signals, mitochondrial transit sequences and chloroplast transit sequences, and membrane localization/anchor sequences such as stop transfer sequences and GPI anchor sequences.
Alternatively, the protein of the invention is fused to another protein that has preferably biological activity. An example hereof is a hybrid polypeptide whereby the polypeptide of the invention is fused to a CBH1. Optionally, the protein of the invention is flanked on the C-terminal and/or the N-terminal side by an amino acid motif that facilitates identification, isolation and/or purification. Such amino acid motif may be β- galactosidase, alkaline phosphatase, GFP, RFP, polyarginine-tag, polyhistidine-tag, FLAG-tag, myc-tag, VSV-tag, HA-tag, and Protein A. Preferably, a fusion protein of the invention is produced by standard recombinant DNA techniques. For example, DNA fragments coding for the different polypeptide sequences are ligated together in-frame in accordance with conventional techniques, for example by employing blunt-ended or stagger-ended termini for ligation, restriction enzyme digestion to provide for appropriate termini, filling-in of cohesive ends as appropriate, alkaline phosphatase treatment to avoid undesirable joining, and enzymatic ligation. In another embodiment, the fusion gene can be synthesized by conventional techniques including automated DNA synthesizers. Alternatively, PCR amplification of gene fragments can be carried out using anchor primers, which give rise to complementary overhangs between two consecutive gene fragments which can subsequently be annealed and reamplified to generate a chimeric gene sequence (see, for example, Current Protocols in Molecular Biology, eds. Ausubel et al. John Wiley & Sons: 1992). Moreover, many expression vectors are commercially available that already encode a fusion moiety (e.g., a GST polypeptide). A nucleic acid encoding the protein of the invention can be cloned into such an expression vector such that the fusion moiety is linked in-frame to the protein of the invention.
(Over)expression
In a preferred embodiment, the polynucleotides of the present invention as described herein may be over-expressed in a microbial strain of the invention compared to the parent microbial strain in which said gene is not over-expressed. Over-expression of a polynucleotide sequence is defined herein as the expression of the said sequence gene which results in an activity of the polypeptide encoded by the said sequence in a microbial strain being at least 1 .1 , at least 1.25 or at least 1 .5-fold the activity of the polypeptide in the parent microbial; preferably the activity of said polypeptide is at least 2-fold, more preferably at least 3-fold, more preferably at least 4-fold, more preferably at least 5-fold, even more preferably at least 10-fold and most preferably at least 20-fold the activity of the polypeptide in the parent microbial.
The vector may further include sequences flanking the polynucleotide giving rise to RNA which comprise sequences homologous to eukaryotic genomic sequences or viral genomic sequences. This will allow the introduction of the polynucleotides of the invention into the genome of a host cell.
An integrative cloning vector may integrate at random or at a predetermined target locus in the chromosome(s) of the host cell into which it is to be integrated. In a preferred embodiment of the invention, an integrative cloning vector may comprise a DNA fragment which is homologous to a DNA sequence in a predetermined target locus in the genome of host cell for targeting the integration of the cloning vector to this predetermined locus. In order to promote targeted integration, the cloning vector may be preferably linearized prior to transformation of the host cell. Linearization may preferably be performed such that at least one but preferably either end of the cloning vector is flanked by sequences homologous to the target locus. The length of the homologous sequences flanking the target locus is preferably at least about 0.1 kb, such as about at least 0.2kb, more preferably at least about 0.5 kb, even more preferably at least about 1 kb, most preferably at least about 2 kb. Preferably, the parent host strains may be modified for improved frequency of targeted DNA integration as described in WO05/095624 and/or WO2007/1 15886.
Vector DNA can be introduced into prokaryotic or eukaryotic cells via conventional transformation or transfection techniques. As used herein, the terms "transformation" and "transfection" are intended to refer to a variety of art-recognized techniques for introducing foreign nucleic acid (e.g., DNA) into a host cell, including calcium phosphate or calcium chloride co-precipitation, DEAE-dextran-mediated transfection, transduction, infection, lipofection, cationic lipid-mediated transfection or electroporation. Suitable methods for transforming or transfecting host cells can be found in Sambrook, et al. (Molecular Cloning: A Laboratory Manual, 2nd, ed. Cold Spring Harbor Laboratory, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1989), Davis et al., Basic Methods in Molecular Biology (1986) and other laboratory manuals.
The person skilled in the art knows how to transform cells with the one or more expression cassettes and the selectable marker. For example, the skilled person may use one or more expression vectors, wherein the one or more cloning vectors comprise the expression cassettes and the selectable marker.
Transformation of the mutant microbial host cell may be conducted by any suitable known methods, including e.g. electroporation methods, particle bombardment or microprojectile bombardment, protoplast methods and Agrobacterium mediated transformation (AMT). Preferably the protoplast method is used. Procedures for transformation are described by J.R.S. Fincham, Transformation in fungi. 1989, Microbiological reviews. 53, 148-170.
Transformation may involve a process consisting of protoplast formation, transformation of the protoplasts, and regeneration of the cell wall in a manner known per se. Suitable procedures for transformation of Aspergillus cells are described in EP 238 023 and Yelton et al., 1984, Proceedings of the National Academy of Sciences USA 81 :1470- 1474. Suitable procedures for transformation of Aspergillus and other filamentous fungal host cells using Agrobacterium tumefaciens are described in e.g. De Groot et al., Agrobacterium tumefaciens-mediated transformation of filamentous fungi. Nat Biotechnol. 1998, 16:839-842. Erratum in: Nat Biotechnol 1998 16:1074. A suitable method of transforming Fusarium species is described by Malardier et al., 1989, Gene 78:147156 or in WO 96/00787. Other methods can be applied such as a method using biolistic transformation as described in: Christiansen et al., Biolistic transformation of the obligate plant pathogenic fungus, Erysiphe graminis f.sp. hordei. 1995, Curr Genet. 29:100-102. Yeast may be transformed using the procedures described by Becker and Guarente, In Abelson, J. N. and Simon, M. I., editors, Guide to Yeast Genetics and Molecular Biology, Methods in Enzymology, Volume 194, pp 182-187, Academic Press, Inc., New York; Ito et a/., 1983, Journal of Bacteriology 153: 163; and Hinnen et al., 1978, Proceedings of the National Academy of Sciences USA 75: 1920.
In order to enhance the amount of copies of the polynucleotide coding for the compound of interest or coding for a compound involved in the production by the cell of the compound of interest (the gene) in the mutated microbial host cell, multiple transformations of the host cell may be required. In this way, the ratios of the different polypeptides produced by the host cell may be influenced. Also, an expression vector may comprise multiple expression cassettes to increase the amount of copies of the polynucleotide(s) to be transformed.
Another way could be to choose different control sequences for the different polynucleotides, which - depending on the choice - may cause a higher or a lower production of the desired polypeptide(s).
The cells transformed with the selectable marker can be selected based on the presence of the selectable marker. In case of transformation of (Aspergillus) cells, usually when the cell is transformed with all nucleic acid material at the same time, when the selectable marker is present also the polynucleotide(s) encoding the desired polypeptide(s) are present.
For stable transfection of mammalian cells, it is known that, depending upon the expression vector and transfection technique used, only a small fraction of cells may integrate the foreign DNA into their genome. In order to identify and select these integrants, a gene that encodes a selectable marker (e.g., resistance to antibiotics) is generally introduced into the host cells along with the gene of interest. Preferred selectable markers include, but are not limited to, those which confer resistance to drugs or which complement a defect in the host cell. A selectable marker is a gene which allow for selection of cells transformed with such gene and which provides for biocide or viral resistance, resistance to heavy metals, prototrophy to auxotrophs, and the like. The selectable marker may be introduced into the cell on the expression vector as the expression cassette or may be introduced on a separate expression vector.
Preferred selectable markers include, but are not limited to, those which confer resistance to drugs or which complement a defect in the host cell. They include e. g. versatile marker genes that can be used for transformation of most filamentous fungi and yeasts such as acetamidase genes or cDNAs (the amdS, niaD, facA genes or cDNAs from A. nidulans, A. oryzae or A. niger), or genes providing resistance to antibiotics like G418, hygromycin, bleomycin, kanamycin, nourseothricin, methotrexate, phleomycin orbenomyl resistance (benA).
Alternatively, specific selection markers can be used such as auxotrophic markers which require corresponding mutant host strains: e. g.URA3 (from S. cerevisiae or analogous genes from other yeasts), pyrG or pyrA (from A. nidulans or A. niger), argB (from A. nidulans or A. niger) or trpC. In a preferred embodiment the selection marker is deleted from the transformed host cell after introduction of the expression construct so as to obtain transformed host cells which are free of selection marker genes.
Other markers include ATP synthetase, subunit 9 (oliC), orotidine-5'- phosphatedecarboxylase (pvrA), the bacterial G418 resistance gene (this may also be used in yeast, but not in fungi), the ampicillin resistance gene (E. coli), the neomycin resistance gene (Bacillus) and the E. coli uidA gene, coding for β-glucuronidase (GUS).
The term selectable marker extends to a marker gene used for screening, i.e. marker gene that, once introduced into a host cell confers to the cell a visible phenotype and causes the cell look different. An example of marker for screening is the gene coding for the Green fluorescent protein which causes cells glow green under UV light.
Expression of proteins in prokaryotes is often carried out in E. coli with vectors containing constitutive or inducible promoters directing the expression of either fusion or non-fusion proteins. Fusion vectors add a number of amino acids to a protein encoded therein, e.g. to the amino terminus of the recombinant protein. Such fusion vectors typically serve three purposes: 1 ) to increase expression of recombinant protein; 2) to increase the solubility of the recombinant protein; and 3) to aid in the purification of the recombinant protein by acting as a ligand in affinity purification. Often, in fusion expression vectors, a proteolytic cleavage site is introduced at the junction of the fusion moiety and the recombinant protein to enable separation of the recombinant protein from the fusion moiety subsequent to purification of the fusion protein.
As indicated, the expression vectors will preferably contain selectable markers. Such markers include dihydrofolate reductase or neomycin resistance for eukaryotic cell culture and tetracyline or ampicillin resistance for culturing in E. coli and other bacteria.
Vectors preferred for use in bacteria are for example disclosed in WO-A1 - 2004/074468, which are hereby enclosed by reference. Other suitable vectors will be readily apparent to the skilled artisan.
For secretion of the translated protein into the lumen of the endoplasmic reticulum, into the periplasmic space or into the extracellular environment, appropriate secretion signal may be incorporated into the expressed polypeptide. The signals may be endogenous to the polypeptide or they may be heterologous signals.
The protein of the invention may be expressed in a modified form, such as a fusion protein, and may include not only secretion signals but also additional heterologous functional regions. Thus, for instance, a region of additional amino acids, particularly charged amino acids, may be added to the N-terminus of the polypeptide to improve stability and persistence in the host cell, during purification or during subsequent handling and storage. Also, peptide moieties may be added to the polypeptide to facilitate purification
The invention provides an isolated polypeptide having the amino acid sequence according to SEQ ID NO: 20501 to 32240, and an amino acid sequence obtainable by expressing the polynucleotide of SEQ ID NO: 1 to 20500 in an appropriate host. Also, a peptide or polypeptide comprising a variant of the above polypeptides, such as a functional equivalent, is comprised within the present invention. The above polypeptides are collectively comprised in the term "polypeptides according to the invention"
As used herein, the terms "variant, "derivative", "mutant" or "homologue" can be used interchangeably. They can refer to either polypeptides or nucleic acids. Variants include substitutions, insertions, deletions, truncations, transversions, and/or inversions, at one or more locations relative to a reference sequence. Variants can be made for example by site-saturation mutagenesis, scanning mutagenesis, insertional mutagenesis, random mutagenesis, site-directed mutagenesis, and directed-evolution, as well as various other recombination approaches. Variant polypeptides may differ from a reference polypeptide by a small number of amino acid residues and may be defined by their level of primary amino acid sequence homology/identity with a reference polypeptide. In general related polypeptides may have several essential amino acids in common (which are sometimes referred to as motif). The identity of those essential amino acids can be identified from the alignment of related polypeptides. Mutating of one or more of the essential amino acids may change the properties of the polypeptide such as substrate specificity, thermostability or change of pH optimum. Mutating of one or more of the non-essential amino acids may have smaller effect on the properties of the polypeptide such as substrate specificity, thermostability or change of pH optimum. Preferably, variant polypeptides have at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 91 %, at least 92%, at least 93%, at least 94%, at least 95%, at least 96%, at least 97%, at least 98%, or even at least 99% amino acid sequence identity with a reference polypeptide. Methods for determining percent identity are known in the art and described herein. Generally, the variants retain the characteristic nature of the reference polypeptide, but have altered properties in some specific aspects. For example, a variant may have a modified pH optimum, a modified substrate binding ability, a modified resistance to enzymatic degradation or other degradation, an increased or decreased activity, a modified temperature or oxidative stability, but retains its characteristic functionality. Variants further include polypeptides with chemical modifications that change the characteristics of a reference polypeptide.
With regard to nucleic acids, the terms refer to a nucleic acid that encodes a variant polypeptide, that has a specified degree of homology/identity with a reference nucleic acid, or that hybridizes under stringent conditions to a reference nucleic acid or the complement thereof. Preferably, a variant nucleic acid has at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 91 %, at least 92%, at least 93%, at least 94%, at least 95%, at least 96%, at least 97%, at least 98%, or even at least 99% nucleic acid sequence identity with a reference nucleic acid. Methods for determining percent identity are known in the art and described herein.
As used herein, the term "polypeptide" refers to a molecule comprising amino acid residues linked by peptide bonds and containing more than five amino acid residues. The amino acids are identified by either the single-letter or three-letter designations. The term "protein" as used herein is synonymous with the term "polypeptide" and may also refer to two or more polypeptides. Thus, the terms "protein", "peptide" and "polypeptide" can be used interchangeably. Polypeptides may optionally be modified (e.g., glycosylated, phosphorylated, acylated, farnesylated, prenylated, sulfonated, and the like) to add functionality. Polypeptides exhibiting catalytic activity may be referred to as enzymes. It will be understood that, as a result of the degeneracy of the genetic code, a multitude of nucleotide sequences encoding a given polypeptide may be produced.
The term "a polypeptide having biological activity" refers to a polypeptide which is encoded by a polynucleotide or a series of polynucleotides (contiguous or noncontiguous) and has an activity or function on other compounds or on organisms. For example an enzyme (for example a lipase) has a catalytic effect (for example on lipids). A signal sequence has a function on its corresponding or fused polypeptide such as a mature protein. Examples of use of the polypeptide or polynucleotide of the invention can be found in the production of a desired protein such as an enzyme which is industrially useful or by the use of the polypeptide or polynucleotide of the invention to affect directly and indirectly processes within the cell which may result in an industrial advantage for example by an improved, more efficient, or more pure production of a desired product such as an enzyme by the cell. These proteins or polypeptides having biological activity can be for example categorized according to FunCat (Ruepp, A et al, Nucleic Acids Research, 2004, vol. 32, no. 18, p. 5539) in proteins involved in the metabolism (metabolism, energy, storage protein), information pathways (cell cycle and DNA processing, transcription, protein synthesis, protein fate [folding, modification and destination], protein with binding function or cofactor requirement [structural or catalytic], protein activity regulation), transport (cellular transport, transport facilitation and transport routes), perception and response to stimuli (cellular communication/signal transduction mechanism, cell rescue, defense and virulence, interaction with the cellular environment, interaction with the environment [systemic], transposable elements, viral and plasmid proteins), developmental processes (cell fate, development [systemic], biogenesis of cellular components, cell type differentiation, tissue differentiation, organ differentiation), localization (subcellular localization, cell type localization, tissue localization, organ localization, ubiquitous expression), experimentally uncharacterized or hypothetical (or conserved hypothetical) proteins (classification not yet clear-cut, and unclassified proteins).
An example of a protein or polypeptide having biological activity in an industrial application is an enzyme. Enzymes are used in the chemical industry and other industrial applications when specific catalysts are required. Enzymes in general are limited in the number of reactions they have evolved to catalyze and their deactivation at high temperatures. As a consequence, protein engineering is an active area of research and involves attempts to create new enzymes with novel properties, either through rational design or in vitro evolution. These efforts have begun to be successful, and a few enzymes have now been designed to improve enzymatic reactions. For designing it is essential to have starting sequences from useful microorganisms especially thermophilic microorganisms like fungi.
Enzymes can be categorized using their Enzyme Commission number (EC number) which is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze. As a system of enzyme nomenclature, every EC number is associated with a recommended name for the respective enzyme. Strictly speaking, EC numbers do not specify enzymes, but enzyme-catalyzed reactions. If different enzymes (for instance from different organisms) catalyze the same reaction, then they receive the same EC number (Moss, G.P. "Recommendations of the Nomenclature Committee". International Union of Biochemistry and Molecular Biology on the Nomenclature and Classification of Enzymes by the Reactions they Catalyse) .By contrast, UniProt identifiers uniquely specify a protein by its amino acid sequence.
Top-level EC numbers:
EC 1 (Oxidoreductases) To catalyze oxidation/reduction reactions; transfer of H and O atoms or electrons from one substance to another.
EC 2 (Transferases) Transfer of a functional group from one substance to another. The group may be methyl-, acyl-, amino- or phosphate group.
EC 3 (Hydrolases) Formation of two products from a substrate by hydrolysis.
EC 4 (Lyases) Non-hydrolytic addition or removal of groups from substrates. C-C, C-N, C-0 or C-S bonds may be cleaved
EC 5 (Isomerases) Intramolecule rearrangement, i.e. isomerization changes within a single molecule.
EC 6 (Ligases) Join together two molecules by synthesis of new C-O, C-S, C-N or C-C bonds with simultaneous breakdown of ATP.
A preferred polypeptide having biological activity is a polypeptide such as an enzyme, more preferably is an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase or is capable to alter or influence the expression of an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase and most preferably is a carbohydrate degrading enzyme and/or carbohydrate hydrolysing enzyme, preferably has an activity mentioned in Table 1 .
The polypeptide of the invention is preferably an enzyme such as an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase or is capable to alter or influence the expression of an enzyme such as oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase, preferably is an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase or is capable to alter or influence the expression of an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase, more preferably is an oxidoreductase or hydrolase or is capable to alter or influence the expression of an oxidoreductase or hydrolase and most preferably has the activity mentioned in Table 1 . A polypeptide which is capable to alter or influence the expression of another polypeptide may be, but is not limited to, a polypeptide having transcriptional activation activity, or having transcription repressing activity (transcriptor factor or repressor) or a polypeptide having saccharide transporter activity.
By a polypeptide having transcriptional activation activity or transcriptional activator is meant a polypeptide which has the capability to activate transcription from a specific promoter or a set of promoters, for example a cellulase promoter, said activator being necessary for the initiation of transcription of the matching protein (such as cellulase(s)) encoding sequence to which the promoter(s) is (are) operably linked to.
By a polypeptide having transcriptional repressing activity or transcriptional repressor is meant a polypeptide which has the capability to repress transcription from a specific promoter or a set of promoters, for example a cellulase promoter, said repressor being necessary for the regulation of transcription of the matching protein (such as cellulase(s)) encoding sequence to which the promoter(s) is (are) operably linked to.
By a polypeptide having saccharide transporter activity or saccharide transporter is meant a polypeptide which has the capability to transport saccharides between the extracellular environment across the plasma membrane and the host cell. Transporters may influence processes like expression in multiple ways, for example the saccharide transport via saccharide transporters may influence induction of cellulases. By saccharides is meant all saccharides including mono-, di-, oligo- and polysaccharides.
Direct or indirect measurement of the activity of the polypeptide of the invention is a useful way to determine the activity of the polypeptide of the invention.
The biological activity of a polypeptide which is capable to alter or influence the expression of a polypeptide can be determined by measuring the expression, or is preferably determined indirectly through measurement of the activity of the expressed polypeptide such as a cellulase as for example described in the example section herein for determination of the cellulase activity using corn stover as substrate.
The polypeptide of the invention or polypeptide produced using the invention may be comprised in a composition. Preferably, the composition is enriched in such a polypeptide. By "enriched" is meant that the polypeptide in the composition is increased, for example with at least a factor of 1 .1 , preferably 1 .5, more preferably 2 on protein compared to the composition without the overexpressed polypeptide of the invention or polypeptide produced using the invention. The composition may comprise a polypeptide of the invention or polypeptide produced using the invention as the major enzymatic component, e.g., a mono-component composition. Alternatively, the composition may comprise multiple enzymatic activities. The polypeptide compositions may be prepared in accordance with methods known in the art and may be in the form of a liquid or a dry composition. For instance, the polypeptide composition may be in the form of a granulate or a microgranulate. The polypeptide to be included in the composition may be stabilized in accordance with methods known in the art. The dosage of the polypeptide composition of the invention or produced using the invention and other conditions under which the composition is used depend on the ultimate use of the composition.
The term "polypeptide fragment" is defined herein as a polypeptide having one or more amino acids deleted from the amino and/or carboxyl terminus of the parent polypeptide or a homologous sequence thereof.
The term "prepro-peptide" is defined herein as a signal peptide and propeptide present at the amino terminus of a polypeptide, where the propeptide is linked (or fused) in frame to the amino terminus of a polypeptide and the signal peptide is linked in frame (or fused) to the amino terminus of the propeptide region. The term "signal peptide" is defined herein as a peptide linked (fused) in frame to the amino terminus of a polypeptide and directs the polypeptide into the cell" secretory pathway. A pro-peptide may be present between the signal peptide and the amino terminus of the polypeptide. The term "pro-peptide" is an amino acid sequence linked (fused) in frame to the amino terminus of a polypeptide having biological activity, wherein the resultant polypeptide is known as a proenzyme or propolypeptide (or a zymogen in some cases), A propolypeptide is generally biologically inactive and can be converted to a mature active polypeptide by catalytic or autocatalitic cleavage of the propeptide from the propolypeptide.
The enzyme or polypeptide of the invention or polypeptide produced using the inventioncan be recovered and purified from recombinant cell cultures by methods known in the art. Most preferably, high performance liquid chromatography ("HPLC") is employed for purification.
Polypeptides of the invention or polypeptides produced using the inventioninclude naturally purified products, products of chemical synthetic procedures, and products produced by recombinant techniques from a prokaryotic or eukaryotic host, including, for example, bacterial, yeast, higher plant, insect and mammalian cells. Depending upon the host employed in a recombinant production procedure, the polypeptides of the invention or polypeptides produced using the invention may be glycosylated or may be non-glycosylated. In addition, polypeptides of the invention or polypeptides produced using the invention may also include an initial modified methionine residue, in some cases as a result of host-mediated processes.
The invention also features biologically active fragments of the polypeptides according to the invention.
Biologically active fragments of a polypeptide of the invention include polypeptides comprising amino acid sequences sufficiently identical to or derived from the amino acid sequence of the protein of the invention (e.g., the amino acid sequence of SEQ ID NO: SEQ ID NO: 20501 to 32240), which include fewer amino acids than the full length protein but which exhibit at least one biological activity of the corresponding full-length protein. Typically, biologically active fragments comprise a domain or motif with at least one activity of the protein of the invention.
A biologically active fragment of a protein of the invention can be a polypeptide which is, for example, about 10, about 25, about 50, about 100 or more amino acids in length or at least about 100 amino acids, at least 150, 200, 250, 300, 350, 400 amino acids in length, or of a length up the total number of amino acids of polypeptide of the invention.
Moreover, other biologically active portions, in which other regions of the protein are deleted, can be prepared by recombinant techniques and evaluated for one or more of the biological activities of the native form of a polypeptide of the invention. The invention also features nucleic acid fragments which encode the above biologically active fragments of the protein of the invention.
In another aspect of the invention, improved polypeptides of the invention are provided. Improved polypeptides of the invention are polypeptides wherein at least one biological activity is improved. Such polypeptides may be obtained by randomly introducing mutations along all or part of the coding sequence of the polypeptide of the invention, such as by saturation mutagenesis, and the resulting mutants can be expressed recombinantly and screened for biological activity. For instance, the art provides for standard assays for measuring the activity of the polypeptide according to the invention and thus improved proteins may easily be selected.
Improved variants of the amino acid sequences of the present invention leading to an improved biological activity may be obtained by the corresponding genes of the present invention. Among such modifications are included: 1 . Error prone PCR to introduce random mutations, followed by a screening of obtained variants and isolating of variants with improved kinetic properties
2. Family shuffling of related variants of the genes encoding the polypeptide according to the invention, followed by a screening of obtained variants and isolating of variants with improved kinetic properties
Variants of the genes of the present invention leading to an increased level of mRNA and/or protein, resulting in more biological activity may be obtained by the polynucleotide sequences of said genes. Among such modifications are included:
1 . Improving the codon usage in such a way that the codons are (optimally) adapted to the parent microbial host.
2. Improving the codon pair usage in such a way that the codons are (optimally)adapted to the parent microbial host
3. Addition of stabilizing sequences to the genomic information encoding the polypeptide according to the invention resulting in mRNA molecules with an increased half life
Preferred methods to isolate variants with improved catalytic properties or increased levels of mRNA or protein are described in WO03/010183 and WO03/0131 1. Preferred methods to optimize the codon usage in parent microbial strains are described in PCT/EP2007/05594. Preferred methods for the addition of stabilizing elements to the genes encoding the Polypeptide according to the invention of the invention are described in WO2005/059149.
In a preferred embodiment the protein of the invention has an amino acid sequence according to SEQ ID NO: SEQ ID NO: 20501 to 32240. In another embodiment, the polypeptide of the invention is substantially homologous to the amino acid sequence according to SEQ ID NO: SEQ ID NO: 20501 to 32240 and retains at least one biological activity of a polypeptide according to SEQ ID NO: SEQ ID NO: 20501 to 32240, yet differs in amino acid sequence due to natural variation or mutagenesis as described.
In a further preferred embodiment, the protein of the invention has an amino acid sequence encoded by an isolated nucleic acid fragment capable of hybridizing to a nucleic acid according to SEQ ID NO: 1 to 20500, preferably under highly stringent hybridization conditions.
Accordingly, the protein of the invention is preferably a protein which comprises an amino acid sequence at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 91 %, 92%, 93%, 94%, 95%, 9695%, 96%, 97%, 98%, 97%, 98%, 99% or more homologous to the amino acid sequence shown in SEQ ID NO: 20501 to 32240 and, typically, retains at least one functional activity of the polypeptide according to SEQ ID NO: 20501 to 32240.
According to one aspect of the invention the polypeptide of the invention may comprise the amino acid sequence set out in SEQ ID NO: 20501 to 32240 or an amino acid sequence that differs in 1 , 2, 3, 4, 5, 6, 7, 8, 9, 10, 1 1 or 12 amino acids from the amino acid sequence set out in SEQ ID NO: 20501 to 32240SEQ ID NO: and whereby the polypeptide still has the activity or function of the polypeptide of the invention. The skilled person will appreciate that these minor amino acid changes in the polypeptide of the invention may be present (for example naturally occurring mutations) or made (for example using r-DNA technology) without loss of the protein function or activity. In case these mutations are present in a binding domain, active site, or other functional domain of the polypeptide a property of the polypeptide may change (for example its thermostability) but the polypeptide may keep its biological activity. In case a mutation is present which is not close to the active site, binding domain, or other functional domain, less effect may be expected.
Functional equivalents of a polypeptide according to the invention can also be identified e.g. by screening combinatorial libraries of mutants, e.g. truncation mutants, of the polypeptide of the invention for the biological activity of the polypeptide of the invention. In one embodiment, a variegated library of variants is generated by combinatorial mutagenesis at the nucleic acid level. A variegated library of variants can be produced by, for example, enzymatically ligating a mixture of synthetic oligonucleotides into gene sequences such that a degenerate set of potential protein sequences is expressible as individual polypeptides, or alternatively, as a set of larger fusion proteins (e.g. for phage display). There are a variety of methods that can be used to produce libraries of potential variants of the polypeptides of the invention from a degenerate oligonucleotide sequence. Methods for synthesizing degenerate oligonucleotides are known in the art (see, e.g., Narang (1983) Tetrahedron 39:3; Itakura et al. (1984) Annu. Rev. Biochem. 53:323; Itakura et al. (1984) Science 198:1056; Ike et al. (1983) Nucleic Acid Res. 1 1 :477). The term "degenerate nucleic acid sequence" or "degenerate (oligo)nucleotide sequence" denotes a sequence of nucleic acids that includes one or more degenerate codons (as compared to a reference nucleic acid molecule that encodes a polypeptide). Degenerate codons contain different triplets of nucleic acids, but encode the same amino acid residue (i.e., GAU and GAC triplets each encode Asp). The codon degeneracy refers to the nature of the genetic code permitting variation of the nucleic acid sequence without affecting the aminoacid sequence of an encoded polypeptide. The skilled artisan is well aware of the "codon-bias" exhibited by a specific host cell in usage of nucleic acid codons to specify a given amino acid.
In addition, libraries of fragments of the coding sequence of a polypeptide of the invention can be used to generate a variegated population of polypeptides for screening a subsequent selection of variants. For example, a library of coding sequence fragments can be generated by treating a double stranded PCR fragment of the coding sequence of interest with a nuclease under conditions wherein nicking occurs only about once per molecule, denaturing the double stranded DNA, renaturing the DNA to form double stranded DNA which can include sense/antisense pairs from different nicked products, removing single stranded portions from reformed duplexes by treatment with S1 nuclease, and ligating the resulting fragment library into an expression vector. By this method, an expression library can be derived which encodes N-terminal and internal fragments of various sizes of the protein of interest.
Several techniques are known in the art for screening gene products of combinatorial libraries made by point mutations of truncation, and for screening cDNA libraries for gene products having a selected property. The most widely used techniques, which are amenable to high through-put analysis, for screening large gene libraries typically include cloning the gene library into replicable expression vectors, transforming appropriate cells with the resulting library of vectors, and expressing the combinatorial genes under conditions in which detection of a desired activity facilitates isolation of the vector encoding the gene whose product was detected. Recursive ensemble mutagenesis (REM), a technique which enhances the frequency of functional mutants in the libraries, can be used in combination with the screening assays to identify variants of a protein of the invention (Arkin and Yourvan (1992) Proc. Natl. Acad. Sci. USA 89:781 1 - 7815; Delgrave et al. (1993) Protein Engineering 6(3): 327-331 ).
In addition to the gene sequence encoding the protein of the invention shown in SEQ ID NO: 1 to 20500, it will be apparent for the person skilled in the art that DNA sequence polymorphisms may exist within a given population, which may lead to changes in the amino acid sequence of the protein of the invention. Such genetic polymorphisms may exist in cells from different populations or within a population due to natural allelic variation. Allelic variants may also include functional equivalents. Fragments of a polynucleotide according to the invention may also comprise polynucleotides not encoding functional polypeptides. Such polynucleotides may function as probes or primers for a PCR reaction.
Methods of inactivation
As used herein the expression "inactivated mutant" or "inactivated cell" means a genetically engineered or a classical mutated cell having a gene which inactivated by a non-reversible inactivation, the inactivation includes inactivation in the protein-coding region. Inactivation of a microbial host cell in the production of the protein of the invention is herein defined as a phenotypic feature wherein the cell, due to modification in the genome: a) produces less of the protein of the invention as compared to the parent microbial host cell that has not been modified in its genome according to the invention, when analyzed under substantially identical conditions.
Inactivation of a gene of a microbial host cell may be a result of a change or modification in a polynucleotide sequence in the genome of the cell. Inactivation includes any method that prevents the functional expression of a selected protein, wherein the gene or the gene product is unable to carry out its function. Modification can be introduced by classical strain improvement, random mutagenesis followed by selection. Modification may be accomplished by the introduction (insertion), substitution or removal (deletion) of one or more nucleotides in a nucleotide sequence. This modification may for example be in a coding sequence or a regulatory element required for the transcription or translation of the polynucleotide. For example, nucleotides may be inserted or removed so as to result in the introduction of a stop codon, the removal of a start codon or a change or a frame-shift of the open reading frame of a coding sequence. The modification of a coding sequence or a regulatory element thereof may be accomplished by site-directed or random mutagenesis, DNA shuffling methods, DNA reassembly methods, gene synthesis (see for example Young and Dong, (2004), Nucleic Acids Research 32, (7) electronic access http://nar.oupjournais.Org/cai/reDrint/32/7/e59 or Gupta et al. (1968), Proc. Natl. Acad. Sci USA, 60: 1338-1344; Scarpulla et al. (1982), Anal. Biochem. 121: 356-365; Stemmer et al. (1995), Gene 164: 49-53), or PCR generated mutagenesis in accordance with methods known in the art. Examples of random mutagenesis procedures are well known in the art, such as for example chemical (NTG for example) mutagenesis or physical (UV for example) mutagenesis. Examples of directed mutagenesis procedures are the QuickChangea site-directed mutagenesis kit (Stratagene Cloning Systems, La Jolla, CA), the The Altered Sites® II in vitro Mutagenesis Systems' (Promega Corporation) or by overlap extension using PCR as described in Gene. 1989 Apr 15;77(1 ):51 -9. (Ho SN, Hunt HD, Horton RM, Pullen JK, Pease LR "Site-directed mutagenesis by overlap extension using the polymerase chain reaction") or using PCR as described in Molecular Biology: Current Innovations and Future Trends. (Eds. A.M. Griffin and H.G.Griffin. ISBN 1 -898486-01 -8;1995 Horizon Scientific Press, PO Box 1 , Wymondham, Norfolk, U.K.).
Preferred methods of modification or inactivation are based on techniques of gene replacement, gene deletion, or gene disruption.
For example, in case of replacement of a polynucleotide, nucleic acid construct or expression cassette, an appropriate DNA sequence may be introduced at the target locus to be replaced. The appropriate DNA sequence is preferably present on a cloning vector. Preferred integrative cloning vectors comprise a DNA fragment, which is homologous to the polynucleotide or has homology to the polynucleotides flanking the locus to be replaced for targeting the integration of the cloning vector to this predetermined locus. In order to promote targeted integration, the cloning vector is preferably linearized prior to transformation of the cell. Preferably, linearization is performed such that at least one but preferably either end of the cloning vector is flanked by sequences homologous to the DNA sequence (or flanking sequences) to be replaced. This process is called homologous recombination and this technique may also be used in order to achieve (partial) gene deletion or gene disruption.
For example, for gene disruption, a polynucleotide corresponding to the endogenous polynucleotide may be replaced by a defective polynucleotide, that is a polynucleotide that fails to produce a (fully functional) protein. By homologous recombination, the defective polynucleotide replaces the endogenous polynucleotide. It may be desirable that the defective polynucleotide also encodes a marker, which may be used for selection of transformants in which the nucleic acid sequence has been modified.
Alternatively or in combination with other mentioned techniques, a technique based on in vivo recombination of cosmids in E. coli can be used, as described in: A rapid method for efficient gene replacement in the filamentous fungus Aspergillus nidulans (2000) Chaveroche, M-K., Ghico, J-M. and d'Enfert C; Nucleic acids Research, vol 28, no 22. Alternatively, modification or inactivation, wherein said host cell produces less of or is deficient in the production of a protein such as the protein of the invention encoded by a polynucleotide may be performed by established anti-sense techniques using a nucleotide sequence complementary to the nucleic acid sequence of the polynucleotide. More specifically, expression of the polynucleotide by a host cell may be reduced or eliminated by introducing a nucleotide sequence complementary to the nucleic acid sequence of the polynucleotide, which may be transcribed in the cell and is capable of hybridizing to the mRNA produced in the cell. Under conditions allowing the complementary anti-sense nucleotide sequence to hybridize to the mRNA, the amount of protein translated is thus reduced or eliminated. An example of expressing an antisense- RNA is shown in Appl. Environ. Microbiol. 2000 Feb; 66(2)775-82. (Characterization of a foldase, protein disulfide isomerase A, in the protein secretory pathway of Aspergillus niger. Ngiam C, Jeenes DJ, Punt PJ, Van Den Hondel CA, Archer DB) or (Zrenner R, Willmitzer L, Sonnewald U. Analysis of the expression of potato uridinediphosphate- glucose pyrophosphorylase and its inhibition by antisense RNA. Planta. (1993); 190(2):247-52.).
Furthermore, modification, downregulation or inactivation of a polynucleotide may be obtained via the RNA interference (RNAi) technique (FEMS Microb. Lett. 237 (2004): 317-324). In this method identical sense and antisense parts of the nucleotide sequence, which expression is to be affected, are cloned behind each other with a nucleotide spacer in between, and inserted into an expression vector. After such a molecule is transcribed, formation of small nucleotide fragments will lead to a targeted degradation of the mRNA, which is to be affected. The elimination of the specific mRNA can be to various extents. The RNA interference techniques described in WO2008/053019, WO2005/05672A1 , WO2005/026356A1 , Oliveira et al., "Efficient cloning system for construction of gene silencing vectors in Aspergillus niger" (2008) Appl. Microbiol, and Biotechnol. 80 (5): 917-924 and/or Barnes et al., "siRNA as a molecular tool for use in Aspergillus niger" (2008) Biotechnology Letters 30 (5): 885-890 may be used for downregulation, modification or inactivation of a polynucleotide.
The invention further provides a cell wherein the polynucleotide according to the invention is mutated or deleted from the genome to obtain lower or no expression of the polypeptide encoded by said polynucleotide compared to the cell wherein the polynucleotide of the invention is not mutated or deleted from the genome. Preferably, the downregulation, modification or inactivation in the genome of the microbial host cell used according to the invention is a modification in the genome on at least one position of at least one nucleic acid sequence encoding a protein of interest having at least 70% identity, even more preferably at least 75% identity, even more preferably at least 80% identity, even more preferably at least 85% identity, even more preferably at least 90% identity, for example at least 91 % identity, for example at least 92% identity, for example at least 93% identity, for example at least 94% identity, for example at least 95% identity, for example at least 96% identity, for example at least 97% identity, for example at least 98% identity, for example at least 99% identity, for example 100% identity with a polypeptide according to SEQ ID NO: 20501 to 32240 and/or the modification in the genome of the microbial host cell in the method according to the invention is a modification resulting in the reduction of the amount of at least one mRNA having at least 60% identity, even more preferably at least 65% identity, even more preferably at least 70% identity, even more preferably at least 75% identity, even more preferably at least 80% identity, even more preferably at least 85% identity, even more preferably at least 90% identity, for example at least 91 % identity, for example at least 92% identity, for example at least 93% identity, for example at least 94% identity, for example at least 95% identity, for example at least 96% identity, for example at least 97% identity, for example at least 98% identity, for example at least 99% identity, for example 100% identity with an mRNA according to SEQ ID NO: 1 to 20500.
Therefore inactivation of a microbial host cell may be measured by determining the amount and/or (specific) activity of the protein of the invention produced by the microbial host cell modified in its genome and/or it may be measured by determining the amount of mRNA transcribed from a gene encoding the protein of the invention and/or it may be measured by determining the amount of a product produced by the protein of the invention in a microbial host cell modified in its genome as defined above and/or it may be measured by gene or genome sequencing if compared to the parent host cell which has not been modified in its genome. Inactivation in the production of the protein of the invention can be measured using any assay available to the skilled person, such as transcriptional profiling, Southern blotting, Northern blotting, RT-PCR, Q-PCR, MALDI- TOF analysis, LC-MS, LC/MS-MS and Western blotting. The modification in the DNA sequence can also be determined by comparing the DNA sequence of the modified cell to the sequence of the non-modified cell. Sequencing of DNA and genome sequencing can be done using standard methods known to the person skilled in the art, for example using Sanger sequencing technology and/or next generation sequencing technologies such as lllumina GA2, Roche 454, and the like, as reviewed in Elaine R. Mardis (2008), Next-Generation DNA Sequencing Methods, Annual Review of Genomics and Human Genetics 9: 387-402. The modification in the RNA sequence can also be determined by comparing the RNA sequence of the modified cell to the sequence of the non-modified cell. Sequencing of RNA can be done using standard methods known to the person skilled in the art, for example using next generation sequencing technologies such as lllumina GA2, Roche 454, and the like, as reviewed in Pareek et al., 201 1 Sequencing technologies and genome sequencing, J Appl Genetics 52:413-435.
Host cells
In the context of the present invention the "parent microbial host cell" and the "mutant microbial host cell" may be any type of host cell. The specific embodiments of the mutant microbial host cell are hereafter described. It will be clear to those skilled in the art that embodiments applicable to the mutant microbial host cell are as well applicable to the parent microbial host cell unless otherwise indicated.
Provided also are host cells comprising a polynucleotide or vector of the invention. The polynucleotide may be heterologous to the genome of the host cell.
The term "heterologous" as used herein refers to nucleic acid or amino acid sequences not naturally occurring in a host cell. In other words, the nucleic acid or amino acid sequence is not identical to that naturally found in the host cell. As used herein, the term "endogenous" or "homologous" refers to a nucleic acid or amino acid sequence naturally occurring in a host.
In another embodiment, the invention features cells, e.g., transformed host cells or recombinant host cells that contain a nucleic acid encompassed by the invention. A "transformed cell" or "recombinant cell" is a cell into which (or into an ancestor of which) has been introduced, by means of recombinant DNA techniques, a nucleic acid according to the invention. Both prokaryotic and eukaryotic cells are included, e.g., bacteria, fungi, yeast, and the like, especially preferred are cells from filamentous fungi, such as Aspergillus niger.
As used herein, the terms "transformed" or "transgenic" with reference to a cell mean that the cell has a non-native (heterologous) nucleic acid sequence integrated into its genome or has an episomal plasmid that is maintained through multiple generations. The term is synonymous with the term "recombinant" or "genetically modified". A host cell can be chosen that modulates the expression of the inserted sequences, or modifies and processes the gene product in a specific, desired fashion. Such modifications (e.g., glycosylation) and processing (e.g., cleavage) of protein products may facilitate optimal functioning of the protein.
Various host cells have characteristic and specific mechanisms for post- translational processing and modification of proteins and gene products. Appropriate cell lines or host systems familiar to those of skill in the art of molecular biology and/or microbiology can be chosen to ensure the desired and correct modification and processing of the foreign protein expressed. To this end, eukaryotic host cells that possess the cellular machinery for proper processing of the primary transcript, glycosylation, and phosphorylation of the gene product can be used. Such host cells are well known in the art.
If desired, a cell as described above may be used to in the preparation of a polypeptide of the invention or polypeptide produced using the invention. Such a method typically comprises cultivating a host cell (e. g. transformed or transfected with an expression vector as described above) under conditions to provide for expression (by the vector) of a coding sequence encoding the polypeptide, and optionally recovering the expressed polypeptide. Polynucleotides of the invention can be incorporated into a recombinant replicable vector, e. g. an expression vector. The vector may be used to replicate the nucleic acid in a compatible host cell. Thus in a further embodiment, the invention provides a method of making a polynucleotide of the invention by introducing a polynucleotide of the invention into a replicable vector, introducing the vector into a compatible host cell, and growing the host cell under conditions which bring about the replication of the vector. The vector may be recovered from the host cell.
Preferably the polypeptide is produced as a secreted protein in which case the nucleotide sequence encoding a mature form of the polypeptide in the expression construct is operably linked to a nucleotide sequence encoding a signal sequence. Preferably the signal sequence is native (homologous) to the nucleotide sequence encoding the polypeptide. Alternatively the signal sequence is foreign (heterologous) to the nucleotide sequence encoding the polypeptide, in which case the signal sequence is preferably endogenous to the host cell in which the nucleotide sequence according to the invention is expressed. Examples of suitable signal sequences for yeast host cells are the signal sequences derived from yeast a-factor genes. Similarly, a suitable signal sequence for filamentous fungal host cells is e. g. a signal sequence derived from a filamentous fungal amyloglucosidase (AG) gene, e. g. the A. niger glaA gene. This may be used in combination with the amyloglucosidase (also called (gluco) amylase) promoter itself, as well as in combination with other promoters. Hybrid signal sequences may also be used with the context of the present invention.
Preferred heterologous secretion leader sequences are those originating from the fungal amyloglucosidase (AG) gene (glaA-both 18 and 24 amino acid versions e. g. from Aspergillus), the a-factor gene (yeasts e. g. Saccharomyces and Kluyveromyces) or the oamylase gene (Bacillus).
The vectors may be transformed or transfected into a suitable host cell as described above to provide for expression of a polypeptide of the invention. This process may comprise culturing a host cell transformed with an expression vector as described above under conditions to provide for expression by the vector of a coding sequence encoding the polypeptide.
A host cell as defined herein is an organism suitable for genetic manipulation and one which may be cultured at cell densities useful for industrial production of a target product. A suitable organism may be a microorganism, for example one which may be maintained in a fermentation device. A host cell may be a host cell found in nature or a host cell derived from a parent host cell after genetic manipulation or classical mutagenesis.
A host cell may be a prokaryotic, archaebacterial or eukaryotic host cell.
A prokaryotic host cell may, but is not limited to, a bacterial host cell. The term "bacterial cell" includes both Gram-negative and Gram-positive microorganisms.
An eukaryotic host cell may be, but is not limited to, a yeast, a fungus, an amoeba, an algae, an animal, an insect host cell.
An eukaryotic host cell may be a fungal host cell. "Fungi" include all species of the subdivision Eumycotina (Alexopoulos, C. J., 1962, In: Introductory Mycology, John Wiley & Sons, Inc., New York). The term fungus thus includes among others filamentous fungi and yeast.
"Filamentous fungi" are herein defined as eukaryotic microorganisms that include all filamentous forms of the subdivision Eumycotina and Oomycota (as defined by Hawksworth etal., 1995, supra). The filamentous fungi are characterized by a mycelial wall composed of chitin, cellulose, glucan, chitosan, mannan, and other complex polysaccharides. Vegetative growth is by hyphal elongation and carbon catabolism is obligatory aerobic. Filamentous fungal strains include, but are not limited to, strains of Acremonium, Aspergillus, Agaricus, Aureobasidium, Cryptococcus, Corynascus, Chrysosporium, Filibasidium, Fusarium, Humicola, Magnaporthe, Monascus, Mucor, Myceliophthora, Mortierella, Neocallimastix, Neurospora, Paecilomyces, Penicillium, Piromyces, Phanerochaete Podospora, Pycnoporus, Rhizopus, Schizophyllum, Sordaria, Talaromyces, Rasamsonia, Thermoascus, Thielavia, Tolypocladium, Trametes and Trichoderma. Preferred filamentous fungal strains that may serve as host cells belong to the species Aspergillus niger, Aspergillus oryzae, Aspergillus fumigatus, Penicillium chrysogenum, Penicillium citrinum, Acremonium chrysogenum, Trichoderma reesei, Rasamsonia emersonii (formerly known as Talaromyces emersonii), Aspergillus sojae, Chrysosporium lucknowense, Myceliophtora thermophyla. Reference host cells for the comparison of fermentation characteristics of transformed and untransformed cells, include e.g. Aspergillus niger CBS120.49, CBS 513.88, Aspergillus oryzae ATCC16868, ATCC 20423, IFO 4177, ATCC 101 1 , ATCC 9576, ATCC14488-14491 , ATCC 1 1601 , ATCC12892, Aspergillus fumigatus AF293 (CBS101355), P. chrysogenum CBS 455.95, Penicillium citrinum ATCC 38065, Penicillium chrysogenum P2, Thielavia terrestris NRRL8126, Talaromyces emersonii CBS 124.902, Rasamsonia emersonii CBS393.64, Acremonium chrysogenum ATCC 36225, ATCC 48272, Trichoderma reesei ATCC 26921 , ATCC 56765, ATCC 26921 , Aspergillus sojae ATCC1 1906, Chrysosporium lucknowense ATCC44006 and derivatives of all of these strains. Particularly preferred as filamentous fungal host cell are Aspergillus niger CBS 513.88 and derivatives thereof. An eukaryotic host cell may be a yeast cell. Preferred yeast host cells may be selected from the genera: Saccharomyces (e.g., S. cerevisiae, S. bayanus, S. pastorianus, S. carlsbergensis), Kluyveromyces, Candida (e.g., C. revkaufi, C. pulcherrima, C. tropicalis, C. utilis), Pichia (e.g., P. pastoris), Schizosaccharomyces, Hansenula, Kloeckera, Schwanniomyces, and Yarrowia (e.g., Y. lipolytica (formerly classified as Candida lipolytica)).
Prokaryotic host cells may be bacterial host cells. Bacterial host cell may be Gram negative or Gram positive bacteria. Examples of bacteria include, but are not limited to, bacteria belonging to the genus Bacillus (e.g., B. subtilis, B. amyloliquefaciens, B. licheniformis, B. puntis, B. megaterium, B. halodurans, B. pumilus,), Acinetobacter, Nocardia, Xanthobacter, Escherichia (e.g., E. coli (e.g., strains DH 1 OB, Stbl2, DH5-alpha, DB3, DB3.1 ), DB4, DB5, JDP682 and ccdA-over (e.g., U.S. Application No. 09/518,188))), Streptomyces, Erwinia, Klebsiella, Serratia (e.g., S. marcessans), Pseudomonas (e.g., P. aeruginosa), Salmonella (e.g., S. typhimurium, S. typhi). Bacteria also include, but are not limited to, photosynthetic bacteria (e.g., green non-sulfur bacteria (e.g., Choroflexus bacteria (e.g., C. aurantiacus), Chloronema (e.g., C. gigateum)), green sulfur bacteria (e.g., Chlorobium bacteria (e.g., C. limicola), Pelodictyon (e.g., P. luteolum), purple sulfur bacteria (e.g., Chromatium (e.g., C. okenii)), and purple non-sulfur bacteria (e.g., Rhodospirillum (e.g., R. rubrum), Rhodobacter (e.g. R. sphaeroides, R. capsulatus), and Rhodomicrobium bacteria (e.g., R. vanellii)).
Host cells may be host cells from non-microbial organisms. Examples of such cells, include, but are not limited to, insect cells (e.g., Drosophila (e.g., D. melanogaster), Spodoptera (e.g., S. frugiperda Sf9 or Sf21 cells) and Trichoplusa (e.g., High-Five cells); nematode cells (e.g., C. elegans cells); avian cells; amphibian cells (e.g., Xenopus laevis cells); reptilian cells; and mammalian cells (e.g., NIH3T3, 293, CHO, COS, VERO, C127, BHK, Per-C6, Bowes melanoma and HeLa cells).
According to one embodiment of the invention, when the mutant microbial host cell according to the invention is a filamentous fungal host cell, the mutant microbial host cell may comprise one or more modifications in its genome such that the mutant microbial host cell is deficient in the production of at least one product selected from glucoamylase (glaA), acid stable alpha-amylase (amyA), neutral alpha-amylase (amyBI and amyBII), oxalic acid hydrolase (oahA), a toxin, preferably ochratoxin and/or fumonisin, a protease transcriptional regulator prtT, PepA, a product encoded by the gene hdfA and/or hdfB, a non-ribosomal peptide synthase npsE if compared to a parent host cell and measured under the same conditions.
Therefore, when the mutant microbial host cell according to the invention is a filamentous fungal host cell the host cell may comprise one or more modifications in its genome to result in a deficiency in the production of the major extracellular aspartic protease PepA. For example the host cell according to the invention may further comprise a disruption of the pepA gene encoding the major extracellular aspartic protease PepA.
When the mutant microbial host cell according to the invention is a filamentous fungal host cell the host cell according to the invention may additionally comprises one or more modifications in its genome to result in a deficiency in the production of the product encoded by the hdfA (Ku70) and/or hdfB (Ku80) gene. For example the host cell according to the invention may further comprise a disruption of the hdfA and/or hdfB gene. Filamentous fungal host cells which are deficient in a product encoded by the hdfA and/or hdfB gene have been described in WO 2005/095624 and PCT/EP2013/055051. When the mutant microbial host cell according to the invention is a filamentous fungal host cell the host cell according to the invention may additionally comprise a modification in its genome which results in the deficiency in the production of the non- ribosomal peptide synthase npsE. Such host cells deficient in the production of non- ribosomal peptide synthase npsE have been described in WO2012/001 169 (npsE has a genomic sequence as depicted in SEQ ID NO: 35, a coding sequence depicted in SEQ ID NO: 36, the mRNA depicted in SEQ ID NO: 37 and the nrps protein depicted in SEQ ID NO: 38 of WO2012/001 169).
When the mutant microbial host cell according to the invention is a filamentous fungal host cell the host cell may additionally comprise at least two substantially homologous DNA domains suitable for integration of one or more copies of a polynucleotide encoding a compound of interest wherein at least one of the at least two substantially homologous DNA domains is adapted to have enhanced integration preference for the polynucleotide encoding a compound of interest compared to the substantially homologous DNA domain it originates from, and wherein the substantially homologous DNA domain where the adapted substantially homologous DNA domain originates from has a gene conversion frequency that is at least 10% higher than one of the other of the at least two substantially homologous DNA domains. These cells have been described in WO201 1/009700. Strains containing two or more copies of these substantially homologous DNA domains are also referred hereafter as strain containing two or more amplicons. Examples of host cells comprising such amplicons are e.g. described in van Dijck et al, 2003, Regulatory Toxicology and Pharmacology 28; 27-35: On the safety of a new generation of DSM Aspergillus niger enzyme production strains. In van Dijck et al, an Aspergillus niger strain is described that comprises 7 amplified glucoamylase gene loci, i.e. 7 amplicons. Preferred host cells within this context are filamentous fungus host cells, preferably A. niger host cells, comprising two or more amplicons, preferably two or more glaA amplicons (preferably comprising 3, 4, 5, 6, 7 glaA amplicons) wherein the amplicon which has the highest frequency of gene conversion, has been adapted to have enhanced integration preference for the polynucleotide encoding a compound of interest compared to the amplicon it originates from. Adaptation of the amplicon can be performed according to any one of the methods described in WO201 1/009700 (which is here fully incorporated by reference). An example of these host cells, described in WO201 1/009700, are host cells comprising three glaA amplicons being a BamYW truncated amplicon, a Sa/I truncated amplicon and a BglW truncated amplicon and wherein the BamH\ amplicon has been adapted to have enhanced integration preference for a polynucleotide encoding a compound of interest compared to the BamYW amplicon it originates from. Host cells comprising two or more amplicons wherein one amplicon has been adapted to have enhanced integration preference for a polynucleotide encoding a compound of interest compared to the amplicon it originates from are hereafter referred as host cells comprising an adapted amplicon.
When the mutant microbial host cell according to the invention is a filamentous fungal host cell the host cell according to the invention may additionally comprises a modification of Sec61 . A preferred SEC61 modification is a modification which results in a one-way mutant of SEC61 ; i.e. a mutant wherein the de novo synthesized protein can enter the ER via SEC61 , but the protein cannot leave the ER via SEC61 . Such modifications are extensively described in WO2005/123763. Most preferably, the SEC 61 modification is the S376W mutation in which Serine 376 is replaced by Tryptophan.
Host cells according to the invention include plant cells, and the invention therefore extends to transgenic organisms, such as plants and parts thereof, which contain one or more cells of the invention. The cells may heterologously express the polypeptide of the invention or may heterologously contain one or more of the polynucleotides of the invention. The transgenic (or genetically modified) plant may therefore have inserted (e. g. stably) into its genome a sequence encoding one or more of the polypeptides of the invention. The transformation of plant cells can be performed using known techniques, for example using a Ti or a Ri plasmid from Agrobacterium tumefaciens. The plasmid (or vector) may thus contain sequences necessary to infect a plant, and derivatives of the Ti and/or Ri plasmids may be employed.
Alternatively direct infection of a part of a plant, such as a leaf, root or stem can be effected. In this technique the plant to be infected can be wounded, for example by cutting the plant with a razor or puncturing the plant with a needle or rubbing the plant with an abrasive. The wound is then inoculated with the Agrobacterium. The plant or plant part can then be grown on a suitable culture medium and allowed to develop into a mature plant. Regeneration of transformed cells into genetically modified plants can be achieved by using known techniques, for example by selecting transformed shoots using an antibiotic and by sub-culturing the shoots on a medium containing the appropriate nutrients, plant hormones and the like. The invention also includes cells that have been modified to express the polypeptide of the invention or a variant thereof. Such cells include transient, or preferably stable higher eukaryotic cell lines, such as mammalian cells or insect cells, lower eukaryotic cells, such as yeast and (e. g. filamentous) fungal cells or prokaryotic cells such as bacterial cells.
It is also possible for the proteins of the invention to be transiently expressed in a cell line or on a membrane, such as for example in a baculovirus expression system. Such systems, which are adapted to express the proteins according to the invention, are also included within the scope of the present invention.
According to the present invention, production of the polypeptide of the invention may be performed in an in vitro expression and translation system system. Such systems are known to the person skilled in the art (see Sambrook & Russell; Ausubel, supra), and may e.g. be a rabbit reticulo lysate based system.
According to the present invention, the production of the polypeptide of the invention or polypeptide produced using the invention can be effected by the culturing of microbial expression hosts, which have been transformed with one or more polynucleotides of the present invention, in a conventional nutrient fermentation medium.
Polypeptide/Enzyme production
The recombinant host cells according to the invention may be cultured using procedures known in the art. For each combination of a promoter and a host cell, culture conditions are available which are conducive to the expression the DNA sequence encoding the polypeptide. After reaching the desired cell density or titer of the polypeptide the culture is stopped and the polypeptide is recovered using known procedures.
The fermentation medium can comprise a known culture medium containing a carbon source (e. g. glucose, maltose, molasses, starch, cellulose, xylan, pectin, lignocellolytic biomass hydrolysate, etc.), a nitrogen source (e. g. ammonium sulphate, ammonium nitrate, ammonium chloride, etc.), an organic nitrogen source (e. g. yeast extract, malt extract, peptone, etc.) and inorganic nutrient sources (e. g. phosphate, magnesium, potassium, zinc, iron, etc.). Optionally, an inducer (e. g. cellulose, pectin, xylan, maltose, maltodextrin or xylogalacturonan) may be included.
The selection of the appropriate medium may be based on the choice of expression host and/or based on the regulatory requirements of the expression construct. Such media are known to those skilled in the art. The medium may, if desired, contain additional components favoring the transformed expression hosts over other potentially contaminating microorganisms.
The fermentation can be performed over a period of from about 0.5 to about 30 days. It may be a batch, continuous or fed-batch process, suitably at a temperature in the range of 0-100°C or 0-80°C, for example, from about 0 to about 50°C and/or at a pH, for example, from about 2 to about 10. Preferred fermentation conditions are a temperature in the range of from about 20 to about 45°C and/or at a pH of from about 3 to about 9. The appropriate conditions are usually selected based on the choice of the expression host and the protein to be expressed.
After fermentation, if necessary, the cells can be removed from the fermentation broth by means of centrifugation or filtration. After fermentation has stopped or after removal of the cells, the polypeptide of the invention may then be recovered and, if desired, purified and isolated by conventional means.
Polypeptide/enzyme compositions
The invention provides a composition comprising a cellulase and/or a hemicellulase and/or a pectinase and/or ligninase or a lignin-modifying enzyme and optionally a polypeptide of the invention or polypeptide produced using the invention.
Polypeptides of the composition can be produced by several processes and mixed into the optimal composition, or the polypetides of the composition can be made directly as mixture by one fermentation.
When the polypeptide of the invention is a cellulase, a composition of the invention will typically comprise a hemicellulase and/or a pectinase and/or ligninase or a lignin-modifying enzyme in addition to the polypeptide of the invention.
When the polypeptide of the invention is a hemicellulase, a composition of the invention will typically comprise a cellulase and/or a pectinase and/or ligninase or a lignin-modifying enzyme in addition to the polypeptide of the invention.
When the polypeptide of the invention is a pectinase, a composition of the invention will typically comprise a cellulase and/or a hemicellulase and/or ligninase or a lignin-modifying enzyme in addition to the polypeptide of the invention.
When the polypeptide of the invention is a ligninase or a lignin-modifying enzyme, a composition of the invention will typically comprise a cellulase and/or a hemicellulase and/or a pectinase in addition to the polypeptide of the invention. A composition of the invention or produced using the invention may comprise one, two or three or more classes of cellulase, for example one, two or all of a GH61 , an endo-1 ,4-3-glucanase (EG), an exo-cellobiohydrolase (CBH) and a β-glucosidase (BGL).
A composition of the invention may comprise a polypeptide which has the same enzymatic activity, for example the same type of cellulase, hemicellulase and/or pectinase activity as that provided by a polypeptide of the invention.
A composition of the invention may comprise a polypeptide which has a different type of cellulase activity and/or hemicellulase activity and/or pectinase activity than that provided by a polypeptide of the invention or polypeptide produced using the invention. For example, a composition of the invention may comprise one type of cellulase and/or hemicellulase activity and/or pectinase activity provided by a polypeptide of the invention and a second type of cellulase and/or hemicellulase activity and/or pectinase activity provided by an additional hemicellulase/pectinase.
Herein a carbohydrate degrading enzyme and/or carbohydrate hydrolysing enzyme is any polypeptide which is capable of degrading and/or hydrolysing of carbohydrate or enhancing the degradation and/or hydrolysis of carbohydrate. Examples of carbohydrate degrading and/or carbohydrate hydrolysing enzymes are cellulase, hemicellulase and enzymes having cellulase enhancing activity (such as GH61 ) or hemicellulase enhancing activity. The enzyme or polypeptide of the invention may have a yield increasing effect on top of an enzyme composition designed for (feedstock) hydrolysis such as the compositions produced by TEC-147 or TEC-210 or 4E mix (see Examples). This yield increase is even possible in case of feedstock such as corn stover. This yield increase may be shown as an increase of the amount of glucose released during a fixed hydrolysis period of time compared to the situation without the addition of the present enzyme or enzyme composition. According to another possibility this yield increase may be shown as an similar amount of glucose production with a lower dosage of the 4E or TEC-210 compared to the situation without the addition of the present enzyme or enzyme composition to the regular dosage of the 4E or TEC-210.
Herein, a cellulase is any polypeptide which is capable of degrading and/or hydrolysing of cellulose of cellulose. A polypeptide which is capable of degrading cellulose is one which is capable of catalysing the process of breaking down cellulose into smaller units, either partially, for example into cellodextrins, or completely into glucose monomers. A cellulase according of the invention or cellulase produced using the invention may give rise to a mixed population of cellodextrins and glucose monomers when contacted with the cellulase. Such degradation will typically take place by way of a hydrolysis reaction.
Herein, a hemicellulase is any polypeptide which is capable of degrading and/or hydrolysing of hemicellulose or enhancing the degradation and/or hydrolysis of hemicellulose. That is to say, a hemicellulase may be capable of degrading or one or more of xylan, glucuronoxylan, arabinoxylan, glucomannan and xyloglucan. A polypeptide which is capable of degrading a hemicellulose is one which is capable of catalysing the process of breaking down the hemicellulose into smaller polysaccharides, either partially, for example into oligosaccharides, or completely into sugar monomers, for example hexose or pentose sugar monomers. A hemicellulase may give rise to a mixed population of oligosaccharides and sugar monomers when contacted with the hemicellulase. Such degradation will typically take place by way of a hydrolysis reaction.
Herein, a pectinase is any polypeptide which is capable of degrading or pectin. A polypeptide which is capable of degrading pectin is one which is capable of catalysing the process of breaking down pectin into smaller units, either partially, for example into oligosaccharides, or completely into sugar monomers. A pectinase of the invention or a pectinase produced using the invention may give rise to a mixed population of oligosaccharides and sugar monomers when contacted with the pectinase. Such degradation will typically take place by way of a hydrolysis reaction.
Herein, a ligninase or a lignin-modifying enzyme is any polypeptide which is capable of degrading or modifying lignin or degradation components thereof. A polypeptide which is capable of degrading or modifying lignin is one which is capable of catalysing the process of breaking down lignin into smaller units, either partially, for example into monophenolic compounds. A ligninase or a lignin-modifying enzyme of the invention or lignin-modifying produced using the invention may give rise to a mixed population of phenolic compounds when contacted with the lignin. Such degradation will typically take place by way of an oxidation reaction. Herein, a ligninase or a lignin- modifying enzyme may also be any polypeptide which is capable of degrading phenolic degradation products of lignin. A polypeptide which is capable of degrading phenolic degradation products of lignin is one which is capable of catalysing the process of breaking down phenolic degradation products of lignin into even smaller units, for example by catalysing a ring opening reaction of the phenolic ring. A ligninase or a lignin-modifying enzyme according to the invention may give rise to a mixed population of ring-opened degradation products of phenolic compounds when contacted with the phenolic degradation products of lignin. Such degradation will typically take place by way of an oxidation reaction. The a ligninase or a lignin-modifying enzyme may further be capable of breaking linkages between cellulose or hemicellulose and the lignin or degradation products thereof. Enzymes that can break down lignin include lignin peroxidases, manganese peroxidases, laccases and feruloyl esterases, and other enzymes described in the art known to depolymerize or otherwise break lignin polymers. Also included are enzymes capable of hydrolyzing bonds formed between hemicellulosic sugars (notably arabinose) and lignin. Ligninases include but are not limited to the following group of enzymes: lignin peroxidases (EC 1 .1 1 .14), manganese peroxidases (EC 1.1 1.1 .13), laccases (EC 1.10.3.2) and feruloyl esterases (EC 3.1 .1.73).
Accordingly, a composition of the invention or produced using the invention may comprise the polypeptide of the inventon and further any cellulase, for example, a GH61 , a cellobiohydrolase, an endo-3-1 ,4-glucanase, a β-glucosidase or a β-(1 ,3)(1 ,4)- glucanase.
GH61 (glycoside hydrolase family 6 sometimes referred to EGIV) proteins are oxygen-dependent polysaccharide monooxygenases (PMO's) according to the latest literature. Often in literature these proteins are mentioned to enhance the action of cellulases on lignocellulose substrates. GH61 was originally classified as endoglucanase based on measurement of very weak endo-1 ,4-3-d-glucanase activity in one family member. The term "GH61 " as used herein, is to be understood as a family of enzymes, which share common conserved sequence portions and foldings to be classified in family 61 of the well-established CAZY GH classification system (http://www.cazy.org/GH61 .html). The glycoside hydrolase family 61 is a member of the family of glycoside hydrolases EC 3.2.1. GH61 is used herein as being part of the cellulases.
A composition of the invention may comprise any hemicellulase, for example, an endo-xylanase, a β-xylosidase, a a-L-arabionofuranosidase, an a-D-glucuronidase, an cellobiohydrolase, a feruloyl esterase, a coumaroyl esterase, an a-galactosidase, a β- galactosidase, a β-mannanase or a β-mannosidase.
A composition of the invention may typically comprise the polypeptide of the invention or a polypeptide produced using the invention and at least one cellulase and/or at least one hemicellulase and/or at least one pectinase (one of which is a polypeptide according to the invention). A composition of the invention may comprise a cellobiohydrolase, an endoglucanase and/or a β-glucosidase. Such a composition may also comprise one or more hemicellulases and/or one or more pectinases.
One or more (for example two, three, four or all) of an amylase, a protease, a lipase, a ligninase, a hexosyltransferase or a glucuronidase may be present in a composition of the invention.
"Protease" includes enzymes that hydrolyze peptide bonds (peptidases), as well as enzymes that hydrolyze bonds between peptides and other moieties, such as sugars (glycopeptidases). Many proteases are characterized under EC 3.4, and are suitable for use in the invention incorporated herein by reference. Some specific types of proteases include, cysteine proteases including pepsin, papain and serine proteases including chymotrypsins, carboxypeptidases and metalloendopeptidases.
"Lipase" includes enzymes that hydrolyze lipids, fatty acids, and acylglycerides, including phospoglycerides, lipoproteins, diacylglycerols, and the like. In plants, lipids are used as structural components to limit water loss and pathogen infection. These lipids include waxes derived from fatty acids, as well as cutin and suberin.
"Hexosyltransferase" (2.4.1 -) includes enzymes which are capable of transferring glycosyl groups, more specifically hexosyl groups. In addition to transfer of a glycosyl-group from a glycosyl-containing donor to another glycosyl-containing compound, the acceptor, the enzymes can also transfer the glycosyl-group to water as an acceptor. This reaction is also known as a hydrolysis reaction, instead of a transfer reaction. An example of a hexosyltransferase which may be used in the invention is a β- glucanosyltransferase. Such an enzyme may be able to catalyze degradation of (1 ,3)(1 ,4)glucan and/or cellulose and/or a cellulose degradation product.
"Glucuronidase" includes enzymes that catalyze the hydrolysis of a glucoronoside, for example β-glucuronoside to yield an alcohol. Many glucuronidases have been characterized and may be suitable for use in the invention, for example β- glucuronidase (EC 3.2.1.31 ), hyalurono-glucuronidase (EC 3.2.1.36), glucuronosyl- disulfoglucosamine glucuronidase (3.2.1 .56), glycyrrhizinate β-glucuronidase (3.2.1 .128) or a-D-glucuronidase (EC 3.2.1 .139).
A composition of the invention may comprise an expansin or expansin-like protein, such as a swollenin (see Salheimo et al., Eur. J. Biochem. 269, 4202-421 1 , 2002) or a swollenin-like protein.
Expansins are implicated in loosening of the cell wall structure during plant cell growth. Expansins have been proposed to disrupt hydrogen bonding between cellulose and other cell wall polysaccharides without having hydrolytic activity. In this way, they are thought to allow the sliding of cellulose fibers and enlargement of the cell wall. Swollenin, an expansin-like protein contains an N-terminal Carbohydrate Binding Module Family 1 domain (CBD) and a C-terminal expansin-like domain. For the purposes of this invention, an expansin-like protein or swollenin-like protein may comprise one or both of such domains and/or may disrupt the structure of cell walls (such as disrupting cellulose structure), optionally without producing detectable amounts of reducing sugars.
A composition of the invention may comprise the polypeptide product of a cellulose integrating protein, scaffoldin or a scaffoldin-like protein, for example CipA or CipC from Clostridium thermocellum or Clostridium cellulolyticum respectively.
Scaffoldins and cellulose integrating proteins are multi-functional integrating subunits which may organize cellulolytic subunits into a multi-enzyme complex. This is accomplished by the interaction of two complementary classes of domain, i.e. a cohesion domain on scaffoldin and a dockerin domain on each enzymatic unit. The scaffoldin subunit also bears a cellulose-binding module (CBM) that mediates attachment of the cellulosome to its substrate. A scaffoldin or cellulose integrating protein for the purposes of this invention may comprise one or both of such domains.
A composition of the invention may comprise a cellulose induced protein or modulating protein, for example as encoded by cipl or cip2 gene or similar genes from Trichoderma reesei I Hypocrea jacorina (see Foreman et al., J. Biol. Chem. 278(34), 31988-31997, 2003). The polypeptide product of these genes are bimodular proteins, which contain a cellulose binding module and a domain which function or activity can not be related to known glycosyl hydrolase families. Yet, the presence of a cellulose binding module and the co-regulation of the expression of these genes with cellulases components indicates previously unrecognized activities with potential role in biomass degradation.
A composition of the invention may be composed of a member of each of the classes of the polypeptides mentioned above, several members of one polypeptide class, or any combination of these polypeptide classes.
A composition of the invention may be composed of polypeptides, for example enzymes, from (1 ) commercial suppliers; (2) cloned genes expressing polypeptides, for example enzymes; (3) complex broth (such as that resulting from growth of a microbial strain in media, wherein the strains secrete proteins and enzymes into the media; (4) cell lysates of strains grown as in (3); and/or (5) plant material expressing polypeptides, for example enzymes. Different polypeptides, for example enzymes in a composition of the invention may be obtained from different sources.
Use of the polypeptides
The polypeptides and polypeptide compositions according to the invention may be used in many different applications. For instance they may be used to produce fermentable sugars. The fermentable sugars can then, as part of a biofuel process, be converted into biogas or ethanol, butanol, isobutanol, 2 butanol or other suitable substances. So by fermentable sugars is meant sugars which can be consumed by a microorganism or converted by a microorganism in another product. Alternatively the polypeptide of the invention or the polypeptide produced using the invention may be used as enzyme, for instance in production of food products, in detergent compositions, in the paper and pulp industry and in antibacterial formulations, in pharmaceutical products such as throat lozenges, toothpastes, and mouthwash. Some of the uses will be illustrated in more detail below.
In the uses and methods described below, the components of the compositions described above may be provided concomitantly (i.e. as a single composition per se) or separately or sequentially.
The invention also relates to the use of the polypeptide of the invention, the polypeptide produced using the invention, or composition produced using the invention and compositions in industrial processes.
In principle, a polypeptide or composition of the invention or composition produced using the invention may be used in any process which requires the treatment of a material which comprises polysaccharide. Thus, a polypeptide or composition of the invention may be used in the treatment of polysaccharide material. Herein, polysaccharide material is a material which comprises or consists essential of one or, more typically, more than one polysaccharide.
Typically, plants and material derived therefrom comprise significant quantities of non-starch polysaccharide material. Accordingly, a polypeptide of the invention or a polypeptide produced using the invention may be used in the treatment of a plant or fungal material or a material derived therefrom.
Lignocellulose An important component of plant non-starch polysaccharide material is lignocellulose (also referred to herein as lignocellulolytic biomass). Lignocellulose is plant material that comprises cellulose and hemicellulose and lignin. The carbohydrate polymers (cellulose and hemicelluloses) are tightly bound to the lignin by hydrogen and covalent bonds. Accordingly, a polypeptide of the invention or a polypeptide produced using the invention may be used in the treatment of lignocellulolytic material. Herein, lignocellulolytic material is a material which comprises or consists essential of lignocellulose. Thus, in a method of the invention for the treatment of a non-starch polysaccharide, the non-starch polysaccharide may be a lignocellulosic material/biomass.
Accordingly, the invention provides a method of treating a substrate comprising non-starch polysaccharide in which the treatment comprises the degradation and/or hydrolysis and/or modification of cellulose and/or hemicellulose and/or a pectic substance.
Degradation in this context indicates that the treatment results in the generation of hydrolysis products of cellulose and/or hemicellulose and/or a pectic substance, i.e. saccharides of shorter length are present as result of the treatment than are present in a similar untreated non-starch polysaccharide. Thus, degradation in this context may result in the liberation of oligosaccharides and/or sugar monomers.
All plants contain non-starch polysaccharide as do virtually all plant-derived polysaccharide materials. Accordingly, in a method of the invention for the treatment of substrate comprising a non-starch polysaccharide, said substrate may be provided in the form of a plant or a plant derived material or a material comprising a plant or plant derived material, for example a plant pulp, a plant extract, a foodstuff or ingredient therefore, a fabric, a textile or an item of clothing.
Lignocellulolytic biomass suitable for use in the invention includes biomass and can include virgin biomass and/or non-virgin biomass such as agricultural biomass, commercial organics, construction and demolition debris, municipal solid waste, waste paper and yard waste. Common forms of biomass include trees, shrubs and grasses, wheat, wheat straw, sugar cane bagasse, corn, corn husks, corn cobs, corn kernel including fiber from kernels, products and by-products from milling of grains such as corn, wheat and barley (including wet milling and dry milling) often called "bran or fiber" as well as municipal solid waste, waste paper and yard waste. The biomass can also be, but is not limited to, herbaceous material, agricultural residues, forestry residues, municipal solid wastes, waste paper, and pulp and paper mill residues. "Agricultural biomass" includes branches, bushes, canes, corn and corn husks, energy crops, forests, fruits, flowers, grains, grasses, herbaceous crops, leaves, bark, needles, logs, roots, saplings, short rotation woody crops, shrubs, switch grasses, trees, vegetables, fruit peels, vines, sugar beet pulp, wheat middlings, oat hulls, and hard and soft woods (not including woods with deleterious materials). In addition, agricultural biomass includes organic waste materials generated from agricultural processes including farming and forestry activities, specifically including forestry wood waste. Agricultural biomass may be any of the aforestated singularly or in any combination or mixture thereof. Further examples of suitable biomass are orchard primings, chaparral, mill waste, urban wood waste, municipal waste, logging waste, forest thinnings, short- rotation woody crops, industrial waste, wheat straw, oat straw, rice straw, barley straw, rye straw, flax straw, soy hulls, rice hulls, rice straw, corn gluten feed, oat hulls, sugar cane, corn stover, corn stalks, corn cobs, corn husks, prairie grass, gamagrass, foxtail; sugar beet pulp, citrus fruit pulp, seed hulls, cellulosic animal wastes, lawn clippings, cotton, seaweed, trees, shrubs, grasses, wheat, wheat straw, sugar cane bagasse, corn, corn husks, corn hobs, corn kernel, fiber from kernels, products and by-products from wet or dry milling of grains, municipal solid waste, waste paper, yard waste, herbaceous material, agricultural residues, forestry residues, municipal solid waste, waste paper, pulp, paper mill residues, branches, bushes, canes, corn, corn husks, an energy crop, forest, a fruit, a flower, a grain, a grass, a herbaceous crop, a leaf, bark, a needle, a log, a root, a sapling, a shrub, switch grass, a tree, a vegetable, fruit peel, a vine, sugar beet pulp, wheat middlings, oat hulls, hard or soft wood, organic waste material generated from an agricultural process, forestry wood waste, or a combination of any two or more thereof.
Apart from virgin biomass or feedstocks already processed in food and feed or paper and pulping industries, the biomass/feedstock may additionally be pretreated with heat, mechanical and/or chemical modification or any combination of such methods in order to enhance enzymatic degradation.
Pretreatment
Before enzymatic treatment, the feedstock may optionally be pre-treated with heat, mechanical and/or chemical modification or any combination of such methods in order to to enhance the accessibility of the substrate to enzymatic hydrolysis and/or hydrolyse the hemicellulose and/or solubilize the hemicellulose and/or cellulose and/or lignin, in any way known in the art. The pretreatment may comprise exposing the lignocellulosic material to (hot) water, steam (steam explosion), an acid, a base, a solvent, heat, a peroxide, ozone, mechanical shredding, grinding, milling or rapid depressurization, or a combination of any two or more thereof. This chemical pretreatment is often combined with heat- pretreatment, e.g. between 150 and 220 °C for 1 to 30 minutes.
Presaccharifation
After the pretreatment step, a liquefaction/hydrolysis or presaccharification step involving incubation with an enzyme or enzyme mixture can be utilized. The presaccharification step can be performed at many different temperatures but it is preferred that the presaccharification step occur at the temperature best suited to the enzyme mix being tested, or the predicted enzyme optimum of the enzymes to be tested. The temperature of the presaccharification step may range from about 10 °C to about 95 °C, about 20 °C to about 85 °C, about 30 °C to about 70 °C, about 40 °C to about 60 °C, about 37 °C to about 50 °C, preferably about 37 °C to about 80 °C, more preferably about 60-70 °C even more preferably around 65 °C. The pH of the presaccharification mixture may range from about 2.0 to about 10.0, but is preferably about 3.0 to about 7.0, more preferably about 4.0 to about 6.0, even more preferably about 4.0 to about 5.0. Again, the pH may be adjusted to maximize enzyme activity and may be adjusted with the addition of the enzyme. Comparison of the results of the assay results from this test will allow one to modify the method to best suit the enzymes being tested.
The liquefaction/hydrolysis or presaccharification step reaction may occur from several minutes to several hours, such as from about 1 hour to about 120 hours, preferably from about 2 hours to about 48 hours, more preferably from about 2 to about 24 hours, most preferably for from about 2 to about 6 hours. The cellulase treatment may occur from several minutes to several hours, such as from about 6 hours to about 120 hours, preferably about 12 hours to about 72 hours, more preferably about 24 to 48 hours.
Saccharification
The invention provides a method for producing a sugar from a lignocellulosic material which method comprises contacting a polypeptide of the invention or a polypeptide produced using the invention to a composition of the invention with the lignocellulosic material.
Such a method allows free sugars (monomers) and/or oligosaccharides to be generated from lignocellulosic biomass. These methods involve converting lignocellulosic biomass to free sugars and small oligosaccharides with a polypeptide or composition of the invention or produced using the invention.
The process of converting a complex carbohydrate such as cellulose or lignocellulose into sugars preferably allows conversion into fermentable sugars. Such a process may be referred to as "saccharification" or "hydrolysis". Accordingly, a method of the invention may result in the liberation of one or more hexose and/or pentose sugars, such as one or more of glucose, xylose, arabinose, galactose, galacturonic acid, glucuronic acid, mannose, rhamnose, ribose and fructose.
Accordingly, another aspect of the invention includes methods that utilize the polypeptide of composition or the invention described above together with further enzymes or physical treatments such as temperature and pH to convert the lignocellulosic plant biomass to sugars and oligosaccharides.
While the composition has been discussed as a single mixture it is recognized that the enzymes may be added sequentially where the temperature, pH, and other conditions may be altered to increase the activity of each individual enzyme. Alternatively, an optimum pH and temperature can be determined for the enzyme mixture.
The enzymes are reacted with substrate under any appropriate conditions. For example, enzymes can be incubated at about 25 °C, about 30 °C, about 35 °C, about 37 °C, about 40 °C, about 45 °C, about 50 °C, about 55 °C, about 60 °C, about 65 °C, about 70 °C, about 75 °C, about 80 °C, about 85 °C, about 90 °C or higher. That is, they can be incubated at a temperature of from about 20 °C to about 95 °C, for example in buffers of low to medium ionic strength and/or from low to neutral pH. By "medium ionic strength" is intended that the buffer has an ion concentration of about 200 millimolar (mM) or less for any single ion component. The pH may range from about pH 2.5, about pH 3.0, about pH 3.5, about pH 4.0, about pH 4.5, about pH 5, about pH 5.5, about pH 6, about pH 6.5, about pH 7, about pH 7.5, about pH 8.0, to about pH 8.5. Generally, the pH range will be from about pH 3.0 to about pH 7. For the production of ethanol an acidic medium is preferred, e.g. pH=4, whereas for the production of biogas neutral pH, e.g. pH=7 is desirable. Incubation of enzyme combinations under these conditions results in release or liberation of substantial amounts of the sugar from the lignocellulose. By substantial amount is intended at least 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, 95% or more of available sugar.
The polypeptides, such as enzymes, can be produced either exogenously in microorganisms, yeasts, fungi, bacteria or plants, then isolated and added, for example, to lignocellulosic feedstock. Alternatively, the enzymes are produced, but not isolated, and crude cell mass fermentation broth, or plant material (such as corn stover), and the like may be added to, for example, the feedstock. Alternatively, the crude cell mass or enzyme production medium or plant material may be treated to prevent further microbial growth (for example, by heating or addition of antimicrobial agents), then added to, for example, a feedstock. These crude enzyme mixtures may include the organism producing the enzyme. Alternatively, the enzyme may be produced in a fermentation that uses feedstock (such as corn stover) to provide nutrition to an organism that produces an enzyme(s). In this manner, plants that produce the enzymes may themselves serve as a lignocellulosic feedstock and be added into lignocellulosic feedstock.
Fermentation of sugars
The fermentable sugars can be converted to useful value-added fermentation products, non-limiting examples of which include amino acids, vitamins, pharmaceuticals, animal feed supplements, specialty chemicals, chemical feedstocks, plastics, solvents, fuels, or other organic polymers, lactic acid, and ethanol, including fuel ethanol. In particular the sugars may be used as feedstocks for fermentation into chemicals, plastics, such as for instance succinic acid and (bio) fuels, including ethanol, methanol, butanol synthetic liquid fuels and biogas.
For instance, in the method of the invention, an enzyme or combination of enzymes acts on a lignocellulosic substrate or plant biomass, serving as the feedstock, so as to convert this complex substrate to simple sugars and oligosaccharides for the production of ethanol or other useful fermentation products.
Sugars released from biomass can be converted to useful fermentation products such a one of those including, but not limited to, amino acids, vitamins, pharmaceuticals, animal feed supplements, specialty chemicals, chemical feedstocks, plastics, and ethanol, including fuel ethanol.
Accordingly, the invention provides a method for the preparation of a fermentation product, which method comprises: a. degrading lignocellulose using a method as described herein; and
b. fermentation of the resulting material,
thereby to prepare a fermentation product.
The fermentation may be carried out under aerobic or anaerobic conditions. Preferably, the process is carried out under micro-aerophilic or oxygen limited conditions.
An anaerobic fermentation process is herein defined as a fermentation process run in the absence of oxygen or in which substantially no oxygen is consumed, preferably about 5 or less, about 2.5 or less or about 1 mmol/L/h or less, and wherein organic molecules serve as both electron donor and electron acceptors.
An oxygen-limited fermentation process is a process in which the oxygen consumption is limited by the oxygen transfer from the gas to the liquid. The degree of oxygen limitation is determined by the amount and composition of the ingoing gas flow as well as the actual mixing/mass transfer properties of the fermentation equipment used. Preferably, in a process under oxygen-limited conditions, the rate of oxygen consumption is at least about 5.5, more preferably at least about 6 and even more preferably at least about 7 mmol/L/h.
A method for the preparation of a fermentation product may optionally comprise recovery of the fermentation product.
SSF
Fermentation and Saccharification may also be executed in Simultaneous Saccharification and Fermentation (SSF) mode. One of the advantages of this mode is reduction of the sugar inhibition on enzymatic hydrolysis (Sugar inhibition on cellulases is described by Caminal B&B Vol XXVII Pp 1282-1290).
Fermentation products
Fermentation products which may be produced according to the invention include amino acids, vitamins, pharmaceuticals, animal feed supplements, specialty chemicals, chemical feedstocks, plastics, solvents, fuels, or other organic polymers, lactic acid, and ethanol, including fuel ethanol (the term "ethanol" being understood to include ethyl alcohol or mixtures of ethyl alcohol and water).
Specific value-added products that may be produced by the methods of the invention include, but not limited to, biofuels (including ethanol and butanol and a biogas); lactic acid; a plastic; a specialty chemical; an organic acid, including citric acid, succinic acid, fumaric acid, itaconic acid and maleic acid; 3-hydoxy-propionic acid, acrylic acid; acetic acid; 1 ,3-propane-diol; ethylene, glycerol; a solvent; an animal feed supplement; a pharmaceutical, such as a β-lactam antibiotic or a cephalosporin; vitamins; an amino acid, such as lysine, methionine, tryptophan, threonine, and aspartic acid; an industrial enzyme, such as a protease, a cellulase, an amylase, a glucanase, a lactase, a lipase, a lyase, an oxidoreductases, a transferase or a xylanase; and a chemical feedstock.
Biogas
The invention also provides use of a polypeptide or composition a described herein in a method for the preparation of biogas. Biogas typically refers to a gas produced by the biological breakdown of organic matter, for example non-starch carbohydrate containing material, in the absence of oxygen. Biogas originates from biogenic material and is a type of biofuel. One type of biogas is produced by anaerobic digestion or fermentation of biodegradable materials such as biomass, manure or sewage, municipal waste, and energy crops. This type of biogas is comprised primarily of methane and carbon dioxide. The gas methane can be combusted or oxidized with oxygen. Air contains 21 % oxygen. This energy release allows biogas to be used as a fuel. Biogas can be used as a low-cost fuel in any country for any heating purpose, such as cooking. It can also be utilized in modern waste management facilities where it can be used to run any type of heat engine, to generate either mechanical or electrical power.
The first step in microbial biogas production consists in the enzymatic degradation of polymers and complex substrates (for example non-starch carbohydrate). Accordingly, the invention provides a method for preparation of a biogas in which a substrate comprising non-starch carbohydrate is contacted with a polypeptide or composition of the invention, thereby to yield fermentable material which may be converted into a biogas by an organism such as a microorganism. In such a method, a polypeptide of the invention may be provided by way of an organism, for example a microorganism which expresses such a polypeptide.
Use of enzymes in food products
The polypeptides and compositions of the invention may be used in a method of processing plant material to degrade or modify the cellulose or hemicellulose or pectic substance constituents of the cell walls of the plant or fungal material. Such methods may be useful in the preparation of food product. Accordingly, the invention provides a method for preparing a food product which method comprises incorporating a polypeptide or composition of the invention during preparation of the food product.
The invention also provides a method of processing a plant material which method comprises contacting the plant material with a polypeptide or composition of the invention or produced using the invention to degrade or modify the cellulose in the (plant) material. Preferably, the plant material is a plant pulp or plant extract, such as juices.
The present invention also provides a method for reducing the viscosity, clarity and/or filterability of a plant extract which method comprises contacting the plant extract with a polypeptide or composition of the invention or produced using the invention in an amount effective in degrading cellulose or hemicellulose or pectic substances contained in the plant extract.
Plant and cellulose/hemicellulose/pectic substance-containing materials include plant pulp, parts of plants and plant extracts. In the context of this invention an extract from a plant material is any substance which can be derived from plant material by extraction (mechanical and/or chemical), processing or by other separation techniques. The extract may be juice, nectar, base, or concentrates made thereof. The plant material may comprise or be derived from vegetables, e. g., carrots, celery, onions, legumes or leguminous plants (soy, soybean, peas) or fruit, e. g., pome or seed fruit (apples, pears, quince etc.), grapes, tomatoes, citrus (orange, lemon, lime, mandarin), melons, prunes, cherries, black currants, redcurrants, raspberries, strawberries, cranberries, pineapple and other tropical fruits, trees and parts thereof (e. g. pollen, from pine trees), or cereal (oats, barley, wheat, maize, rice). The material (to be hydrolysed) may also be agricultural residues, such as sugar beet pulp, com cobs, wheat straw, (ground) nutshells, or recyclable materials, e. g. (waste) paper.
The polypeptides of the invention or the polypeptides produced using the invention can thus be used to treat plant material including plant pulp and plant extracts. They may also be used to treat liquid or solid foodstuffs or edible foodstuff ingredients, or be used in the extraction of coffee, plant oils, starch or as a thickener in foods.
Typically, the polypeptides of the invention or the polypeptides produced using the invention are used as a composition/enzyme preparation as described above. The composition will generally be added to plant pulp obtainable by, for example mechanical processing such as crushing or milling plant material. Incubation of the composition with the plant will typically be carried out for at time of from 10 minutes to 5 hours, such as 30 minutes to 2 hours, preferably for about 1 hour. The processing temperature is preferably from about 10°C to about 55°C, e. g. from about 15°C to about 25°C, optimally about 20°C and one can use from about 10 g to about 300 g, preferably from about 30 g to about 70 g, optimally about 50 g of enzyme per ton of material to be treated.
All of the enzyme(s) or their compositions used may be added sequentially or at the same time to the plant pulp. Depending on the composition of the enzyme preparation the plant material may first be macerated (e. g. to a pure) or liquefied. Using the polypeptides of the invention processing parameters such as the yield of the extraction, viscosity of the extract and/or quality of the extract can be improved.
Alternatively, or in addition to the above, a polypeptide of the invention or a polypeptide produced using the invention may be added to the raw juice obtained from pressing or liquefying the plant pulp. Treatment of the raw juice will be carried out in a similar manner to the plant pulp in respect of dosage, temperature and holding time. Again, other enzymes such as those discussed previously may be included. Typical incubation conditions are as described in the previous paragraph.
Once the raw juice has been incubated with the polypeptides of the invention or the polypeptides produced using the invention, the juice is then centrifuged or (ultra) filtered to produce the final product.
After treatment with the polypeptide of the invention or the polypeptide produced using the invention the (end) product can be heat treated, e.g. at about 100°C for a time of from about 1 minute to about 1 hour, under conditions to partially or fully inactivate the polypeptide(s) of the invention or the polypeptide(s) produced using the invention.
A composition containing a polypeptide of the invention or a polypeptide produced using the invention may also be used during the preparation of fruit or vegetable purees.
The polypeptide of the invention may also be used in brewing, wine making, distilling or baking. It may therefore be used in the preparation of alcoholic beverages such as wine and beer. For example it may improve the filterability or clarity, for example of beers, wort (e.g. containing barley and/or sorghum malt) or wine.
Furthermore, a polypeptide or composition of the invention may be used for treatment of brewers spent grain, i.e. residuals from beer wort production containing barley or malted barley or other cereals, so as to improve the utilization of the residuals for, e.g., animal feed.
The protein may assist in the removal of dissolved organic substances from broth or culture media, for example where distillery waste from organic origin is bioconverted into microbial biomass. The polypeptide of the invention or the polypeptide produced using the invention may improve filterability and/or reduce viscosity in glucose syrups, such as from cereals produced by liquefaction (e.g. with a-amylase).
In baking the polypeptide may improve the dough structure, modify its stickiness or suppleness, improve the loaf volume and/or crumb structure or impart better textural characteristics such as break, shred or crumb quality.
The present invention thus relates to methods for preparing a dough or a cereal-based food product comprising incorporating into the dough a polypeptide or composition of the present invention or produced according to the present invention. This may improve one or more properties of the dough or the cereal-based food product obtained from the dough relative to a dough or a cereal-based food product in which the polypeptide is not incorporated.
The preparation of the cereal-based food product according to the invention further can comprise steps known in the art such as boiling, drying, frying, steaming or baking of the obtained dough.
Products that are made from a dough that is boiled are for example boiled noodles, dumplings, products that are made from fried dough are for example doughnuts, beignets, fried noodles, products that are made for steamed dough are for example steamed buns and steamed noodles, examples of products made from dried dough are pasta and dried noodles and examples of products made from baked dough are bread, cookies and cake.
The term "improved property" is defined herein as any property of a dough and/or a product obtained from the dough, particularly a cereal-based food product, which is improved by the action of the polypeptide according to the invention relative to a dough or product in which the polypeptide according to the invention is not incorporated. The improved property may include, but is not limited to, increased strength of the dough, increased elasticity of the dough, increased stability of the dough, improved machinability of the dough, improved proofing resistance of the dough, reduced stickiness of the dough, improved extensibility of the dough, increased volume of the cereal-based food product, reduced blistering of the cereal-based food product, improved crumb structure of the baked product, improved softness of the cereal-based food product, improved flavour of the cereal-based food product, improved anti-staling of the cereal-based food product. Improved properties related to pasta and noodle type of cereal-based products are for example improved firmness, reduced stickiness, improved cohesiveness and reduced cooking loss.
The improved property may be determined by comparison of a dough and/or a cereal-based food product prepared with and without addition of a polypeptide of the invention or a polypeptide produced using the invention. Organoleptic qualities may be evaluated using procedures well established in the baking industry, and may include, for example, the use of a panel of trained taste-testers.
The term "dough" is defined herein as a mixture of cereal flour and other ingredients firm enough to knead or roll. Examples of cereals are wheat, rye, corn, maize, barley, rice, groats, buckwheat and oat. Wheat is I here and hereafter intended to encompass all known species of Triticum genus, for example aestivum, durum and/or spelt. Examples of suitable other ingredients are: the polypeptide or polypeptide composition according to the present invention, additional enzymes, chemical additives and/or processing aids. The dough may be fresh, frozen, pre-pared, or pre-baked. The preparation of dough from the ingredients described above is well known in the art and comprises mixing of said ingredients and processing aids and one or more moulding and optionally fermentation steps. The preparation of frozen dough is described by Kulp and Lorenz in Frozen and Refrigerated Doughs and Batters.
The term "cereal-based food product" is defined herein as any product prepared from a dough, either of a soft or a crisp character. Examples of cereal-based food products, whether of a white, light or dark type, which may be advantageously produced by the present invention are bread (in particular white, whole-meal or rye bread), typically in the form of loaves or rolls, French baguette-type bread, pasta, noodles, doughnuts, bagels, cake, pita bread, tortillas, tacos, cakes, pancakes, biscuits, cookies, pie crusts, steamed bread, and crisp bread, and the like.
The term "baked product" is defined herein as any cereal-based food product prepared by baking the dough.
Non-starch polysaccharides (NSP) can increase the viscosity of the digesta which can, in turn, decrease nutrient availability and animal performance. Adding specific nutrients to feed improves animal digestion and thereby reduces feed costs. A lot of feed additives are being currently used and new concepts are continuously developed. Use of specific enzymes like non-starch carbohydrate degrading enzymes could breakdown the fibre releasing energy as well as increasing the protein digestibility due to better accessibility of the protein when the fibre gets broken down. In this way the feed cost could come down as well as the protein levels in the feed also could be reduced.
Non-starch polysaccharides (NSPs) are also present in virtually all feed ingredients of plant origin. NSPs are poorly utilized and can, when solubilized, exert adverse effects on digestion. Exogenous enzymes can contribute to a better utilization of these NSPs and as a consequence reduce any anti-nutritional effects. Non-starch enzymes or enzyme compositions of the present invention can be used for this purpose in cereal-based diets for poultry and, to a lesser extent, for pigs and other species.
A non-starch polypeptide/enzyme of the invention (of a composition comprising the polypeptide/enzyme of the invention or the polypeptide/enzyme produced using the invention) may be used in the detergent industry, for example for removal from laundry of carbohydrate-based stains. A detergent composition may comprise a polypeptide/enzyme of the invention or a polypeptide/enzyme produced using the invention and, in addition, one or more of a cellulase, a hemicellulase, a pectinase, a protease, a lipase, a cutinase, an amylase or a carbohydrase.
Use of enzymes in detergent compositions
A detergent composition comprising a polypeptide or composition of the invention may be in any convenient form, for example a paste, a gel, a powder or a liquid. A liquid detergent may be aqueous, typically containing up to about 70% water and from about 0 to about 30% organic solvent or non-aqueous material.
Such a detergent composition may, for example, be formulated as a hand or machine laundry detergent composition including a laundry additive composition suitable for pre-treatment of stained fabrics and a rinse added fabric softener composition, or be formulated as a detergent composition for use in general household hard surface cleaning operations, or be formulated for hand or machine dish washing operations.
In general, the properties of the enzyme should be compatible with the aselected detergent (for example, pH-optimum, compatibility with other enzymatic and/or non- enzymatic ingredients, etc.) and the enzyme(s) should be present in an effective amount.
A detergent composition may comprise a surfactant, for example an anionic or non- ionic surfactant, a detergent builder or complexing agent, one or more polymers, a bleaching system (for example an H202 source) or an enzyme stabilizer. A detergent composition may also comprise any other conventional detergent ingredient such as, for example, a conditioner including a clay, a foam booster, a sud suppressor, an anti- corrosion agent, a soil-suspending agent, an an-soil redeposition agent, a dye, a bactericide, an optical brightener, a hydrotropes, a tarnish inhibitor or a perfume.
Use of enzymes in paper and pulp processing
A polypeptide or composition of the present invention may be used in the paper and pulp industry, inter alia in the bleaching process to enhance the brightness of bleached pulps whereby the amount of chlorine used in the bleaching stages may be reduced, and to increase the freeness of pulps in the recycled paper process (Eriksson, K. E. L, Wood Science and Technology 24 (1990)79-101 ; Paice, et al., Biotechnol. and Bioeng. 32 (1988):235-239 and Pommier et al., Tappi Journal (1989):187-191 ). Furthermore, a polypeptide or composition of the invention or a polypeptide or composition produced using the invention may be used for treatment of lignocellulosic pulp so as to improve the bleachability thereof. Thereby the amount of chlorine need to obtain a satisfactory bleaching of the pulp may be reduced.
A polypeptide or composition of the invention may be used in a method of reducing the rate at which cellulose-containing fabrics become harsh or of reducing the harshness of cellulose-containing fabrics, the method comprising treating cellulose- containing fabrics with a polypeptide or composition as described above. The present invention further relates to a method providing colour clarification of coloured cellulose- containing fabrics, the method comprising treating coloured cellulose-containing fabrics with a polypeptide or composition as described above, and a method of providing a localized variation in colour of coloured cellulose-containing fabrics, the method comprising treating coloured cellulose-containing fabrics with a polypeptide or composition as described above. The methods of the invention may be carried out by treating cellulose-containing fabrics during washing. However, if desired, treatment of the fabrics may also be carried out during soaking or rinsing or simply by adding the polypeptide or composition as described above to water in which the fabrics are or will be immersed.
Other enzyme uses In addition, a polypeptide or composition of the present invention can also be used in antibacterial formulation as well as in pharmaceutical products such as throat lozenges, toothpastes, and mouthwash.
The following Examples illustrate the invention:
EXAMPLES
Experimental information
Strains
Aspergillus niger strain was deposited at the CENTRAAL BUREAU VOOR SCHIMMELCULTURES, Uppsalalaan 8, P.O. Box 85167, NL-3508 AD Utrecht, The Netherlands on 10 August 1988 under the deposit number CBS 513.88.
Rasamsonia (Talaromyces) emersonii strain was deposited at CENTRAAL BUREAU VOOR SCHIMMELCULTURES, Uppsalalaan 8, P.O. Box 85167, NL-3508 AD Utrecht, The Netherlands in December 1964 having the Accession Number CBS 393.64.
Other suitable strains can be equally used in the present examples to show the effect and advantages of the invention. For example TEC-101 , TEC-147, TEC-192, TEC- 201 or TEC-210 are suitable Rasamsonia strains wich are described in WO201 1/000949. The "4E mix" or "4E composition" was used containing CBHI, CBHII, EG4 and BG (30wt%, 25wt%, 28wt% and 8wt%, respectively, as described in WO201 1/098577, wt% on dry matter protein.
Rasamsonia (Talaromyces) emersonii strain TEC-101 (also designated as FBG 101 ) was deposited at CENTRAAL BUREAU VOOR SCHIMMELCULTURES, Uppsalalaan 8, P.O. Box 85167, NL-3508 AD Utrecht, The Netherlands on 30th June 2010 having the Accession Number CBS 127450.
Molecular biology techniques
In these strains, using molecular biology techniques known to the skilled person (see: Sambrook & Russell, Molecular Cloning: A Laboratory Manual, 3rd Ed., CSHL Press, Cold Spring Harbor, NY, 2001 ), several genes were over expressed and others were down regulated as described below. Examples of the general design of expression vectors for gene over expression and disruption vectors for down-regulation, transformation, use of markers and selective media can be found in W0199846772, W0199932617, WO2001 121779, WO2005095624, WO2006040312, EP 635574B, WO2005100573, WO201 1009700, WO2012001 169 and WO201 1054899. All gene replacement vectors comprise approximately 1 - 2 kb flanking regions of the respective Open Reading Frame (ORF) sequences, to target for homologous recombination at the predestined genomic loci. In addition, A.niger vectors contain the A. nidulans bidirectional amdS selection marker for transformation, in-between direct repeats. The method applied for gene deletion in all examples herein uses linear DNA, which integrates into the genome at the homologous locus of the flanking sequences by a double cross-over, thus substituting the gene to be deleted by the amdS gene. After transformation, the direct repeats allow for the removal of the selection marker by a (second) homologous recombination event. The removal of the amdS marker can be done by plating on fluoro-acetamide media, resulting in the selection of marker-gene-free strains. Using this strategy of transformation and subsequent counter-selection, which is also described as the "MARKER-GENE FREE" approach in EP 0 635 574, the amdS marker can be used indefinitely in strain modification programs.
Media and solutions:
Potato dextrose agar, PDA, (Fluka, Cat. No. 70139): per litre: Potato extract 4 g; Dextrose 20 g; Bacto agar 15 g; pH 5.4; Sterilize 20 min at 120°C.
Rasamsonia agar medium: per litre: Salt fraction no.3 15 g; Cellulose 30 g; Bacto peptone 7.5 g; Grain flour 15 g; KH2P04 5 g; CaCI2.2aq 1 g; Bacto agar 20 g; pH 6.0; Sterilize 20 min at 120°C.
Salt fraction composition: The "salt fraction no.3" was fitting the disclosure of W098/37179, Table 1 . Deviations from the composition of this Table were CaCI2.2aq 1 .0 g/l, KCI 1 .8 g/L, citric acid 1 aq 0.45 g/L (chelating agent).
Shake flask media for Rasamsonia
Rasamsonia medium 1 : per litre: Glucose 20 g; Yeast extract (Difco) 20 g; Clerol FBA3107 (AF) 4 drops; MES 30 g; pH 6.0; Sterilize 20 min at 120°C.
Rasamsonia medium 2: per litre: Salt fraction no.3 10 g; glucose 10 g; KH2P04 5 g; NaH2P04 2 g; (NH4)2S04 5 g; MES 30 g; pH 5.4; Sterilize 20 min at 120°C.
Rasamsonia medium 3: per litre: Salt fraction no.3 10 g; cellulose 20 g; KH2P04 5 g; NaH2P04 2 g; (NH4)2S04 5 g; MES 30 g; pH 5.4; Sterilize 20 min at 120°C. Rasamsonia medium 4: per litre: Salt fraction no.3 10 g; cellulose 15 g; glucose 5 g; KH2P04 5 g; NaH2P04 2 g; (NH4)2S04 5 g; MES 30 g; pH 5.4; Sterilize 20 min at 120°C.
Spore batch preparation for Rasamsonia
Strains were grown from stocks on Rasamsonia agar medium in 10 cm diameter Petri dishes for 5-7 days at 40°C. For MTP fermentations, strains were grown in 96-well plates containing Rasamsonia agar medium. Strain stocks were stored at -80°C in 10% glycerol.
Chromosomal DNA isolation
Strains were grown in YGG medium (per liter: 8 g KCI, 16 g glucose. H20, 20 ml of 10% yeast extract, 10 ml of 100x pen/strep, 6.66 g YNB+amino acids, 1.5 g citric acid, and 6 g K2HP04) for 16 hours at 42°C, 250 rpm, and chromosomal DNA was isolated using the DNeasy plant mini kit (Qiagen, Hilden, Germany).
Shake flask growth protocol of Rasamsonia Spores were inoculated into 100 ml shake flasks containing 20 ml of Rasamsonia medium 1 and incubated at 45°C at 250 rpm in an incubator shaker for 1 day (preculture 1 ) and 1 or 2 ml of biomass from preculture 1 was transferred to 100 ml shake flasks containing 20 ml of Rasamsonia medium 2 and grown under conditions as described above for 1 day (preculture 2). Subsequently, 1 or 2 ml of biomass from preculture 2 was transferred to 100 ml shake flasks containing 20 ml of Rasamsonia medium 3 or 4 and grown under conditions described above for 3 days.
Protein analysis
Protein samples were separated under reducing conditions on NuPAGE 4-12% Bis-Tris gel (Invitrogen, Breda, The Netherlands) and stained. Gels were stained with either InstantBlue (Expedeon, Cambridge, United Kingdom), SimplyBlue safestain (Invitrogen, Breda, The Netherlands) or Sypro Ruby (Invitrogen, Breda, The Netherlands) according to manufacturer's instructions.
Total protein concentration determination with TCA-biuret method Concentrated protein samples (supernatants) were diluted with water to a concentration between 2 and 8 mg/ml. Bovine serum albumin (BSA) dilutions (0, 1 , 2, 5, 8 and 10 mg/ml) were made and included as samples to generate a calibration curve. 1 ml of each diluted protein sample was transferred into a 10 ml tube containing 1 ml of a 20% (w/v) trichloro acetic acid solution in water and mixed thoroughly. Subsequently, the tubes were incubated on ice water for one hour and centrifuged for 30 minutes, at 4°C and 6000 rpm. The supernatant was discarded and pellets were dried by inverting the tubes on a tissue and letting them stand for 30 minutes at room temperature. Next, 4 ml BioQuant Biuret reagent mix was added to the pellet in the tube and the pellet was solubilised upon mixing. Next, 1 ml water was added to the tube, the tube was mixed thoroughly and incubated at room temperature for 30 minutes. The absorption of the mixture was measured at 546 nm with a water sample used as a blank measurement and the protein concentration was calculated via the BSA calibration line.
Cellulase activity assays
In order to measure cellulase activity corn stover activity assays are performed. Cellulase activity is measured in supernatants (the liquid part of the broth wherein the cells were cultured) of an empty strain and the transformant:
Preparation of pre-treated, corn stover substrate.
Dilute-acid pre-treated corn stover was obtained as described in Schell, D.J., Applied Biochemistry and Biotechnology (2003), vol. 105-108, pp 69-85. A pilot scale pretreatment reactor was used operating at steady state conditions of 190°C, 1 min residence time and an effective H2S04 acid concentration of 1.45% (w/w) in the liquid phase.
Assay 1 : Microtiter plate (MTP) 2% unwashed acid pretreated corn-stover sugar-release assay in which supernatants are spiked on top of TEC-210 or 4E mix
For each (hemi-)cellulase assay, the stored samples were analyzed twice; 100 μΙ_ of sample (e.g. shake flask supernatant) and 100 μΙ of a (hemi-)cellulase base mix [3.5 mg/g DM TEC-210 or a 4 enzyme mix at a total dosage of 3.5 mg/g DM consisting of 0,3 mg/g DM BG (9% of total protein 4E mix), 1 mg/g DM CBHI (30% of total protein 4E mix), 0,9 mg/g DM CBHII (25% of total protein 4E mix) and 1 .3 mg/g DM GH61 (36% of total protein 4E mix)] was transferred to two suitable vials: one vial containing 800 μΙ_ 2.5 % (w/ w) dry matter of the acid pre treated corn stover in a 50 mM citrate buffer, buffered at pH 4.5. The other vial consisted of a blank, where the 800 μΙ_ 2.5 % (w/ w) dry matter, acid pre treated corn stover was replaced by 800 μΙ_ 50 mM citrate buffer, buffered at pH 4.5. The assay samples were incubated for 72 hrs at 65 °C. After incubation of the assay samples, a fixed volume of D20 (with 0.5 g/L DSS) containing an internal standard, maleic acid (20 g/L) and EDTA (40 g/L), was added. The amount of sugar released, is based on the signal between 4.65 - 4.61 ppm, relative to DSS, and is determined by means of 1 D 1 H NMR operating at a proton frequency of 500 MHz, using a pulseprogram with water suppression, at a temperature of 27°C.
The (hemi)-cellulase enzyme solution may contain residual sugars. Therefore, the results of the assay are corrected for the sugar content measured after incubation of the enzyme solution.
Assay 2: Dose-response 2% unwashed acid pretreated corn stover sugar-release assay in MTP
Since glucose release by cellulases is not a linear function of the quantity of enzyme in the composition, in other words, twice the amount of enzyme does not automatically result in twice the amount of glucose at a fixed time point. Therefore the activity of the cellulose enzyme mixture has been assessed in a dose response based assay, in which the dosage is based on equal amount of protein per cellulose mixture tested.
Overall cellulase activity of the mixture measured with unwashed acid pretreated corn stover as substrate. The frozen enzyme samples were thawed and a series of 6 dilutions was made ranging from undiluted in steps of two-fold up to 32-fold in 50 mM citrate buffer pH 4.5.
200 μΙ of sample was transferred to a vial containing 800 μί of 2.5 % (w/w) dry matter of the acid pretreated corn stover in 50 mM citrate buffer, buffered at pH 4.5. Another 200 μΙ sample was transferred to a vial, referred to as blank, containing 800 μΙ of 50 mM citrate buffer, buffered at pH 4.5. In addition, a sugar background of corn stover was determined by incubating 800 μί 2.5 % (w/w) dry matter of the acid pretreated corn stover in 50 mM citrate buffer, buffered at pH 4.5 with 200 μΙ of 50 mM citrate buffer. All vials were incubated for 72 hr at 65 °C. After incubation, 100 μΙ of internal standard solution (20 g/L maleic acid, 40 g/L EDTA in D20) was added to the vials. All vials containing pretreated corn stover were centrifuged for 30 minutes at 5300g and, subsequently, 600 μΙ of the supernatant was transferred to a new vial containing 400 μΙ of H20/D20 9:1 .
The 1 D 1 H-NMR spectra were recorded on an Avance III Bruker operating at a proton frequency of 500 MHz, using a pulse program with water suppression, at a temperature of 27°C. Glucose quantification (arbitrary units) was performed based on the signal at 5.20 ppm, relative to 4,4-Dimethyl-4-silapentane sulfonic acid with relation to the internal standard signal at 6.30 ppm. The relative glucose release (AGIc) was calculated by correcting the glucose measured in the samples by the residual sugar present in the enzyme solution (measured from the blank) and the residual sugar present in the acid pretreated corn stover.
Since the protein concentration of the samples was known the sugar release can be depicted as a function of protein mg/ml of the tested diluted sample versus the relative glucose release at time point 72 hours.
Example 1 : Construction of A. niger expression vectors
This example describes the construction of an expression construct for overexpression of the protein of the invention in A.niger. Genomic DNA of Rasamsonia emersonii strain CBS393.64 was sequenced and analysed. The genes with translated proteins are identified. Sequences of the R. emersonii gene, comprising the protein sequence, signal peptide sequence, genomic sequence and wild-type cDNA sequence and mature protein sequence are shown in sequence listings SEQ ID NO: 1 to 33730.
Construction of expression plasmids
Sequences having SEQ ID NO: 10251 to 20500 are cloned into the pGBTOP vector (Fig. 1 ) using EcoRI and Pad sites, comprising the glucoamylase promoter and terminator sequence. The construction, general layout and use of such a vector is described in detail in W0199932617. The E.coli part is removed by A/oil digestion prior to transformation of A. niger CBS 513.88.
Transformation of A. niger and shake flask fermentations
A. niger strain CBS513.88 is co-transformed with the expression constructs and an appropriate selection marker (amdS or phleomycin) containing plasmid according to method described in the experimental information section. Of recombinant and control A.niger strains a large batch of spores is generated by plating spores or mycelia onto PDA plates (Potato Dextrose Agar, Oxoid), prepared according to manufacturer's instructions. After growth for 3-7 days at 30 degrees Celsius, spores are collected after adding 0.01 % Triton X-100 to the plates. After washing with sterile water about 107 spores of selected transformants and control strains are inoculated into 100 ml shake flasks with baffles containing 20 ml of liquid pre-culture medium consisting of per liter: 30 g maltose. H20; 5 g yeast extract; 10 g hydrolyzed casein; 1 g KH2P04; 0.5 g MgS04.7H20; 0.03 g ZnCI2; 0.02 g CaCI2; 0.01 g MnS04.4H20; 0.3 g FeS04.7H20; 3 g Tween 80; 10 ml penicillin (5000 IU/ml)/Streptomycin (5000UG/ml); pH5.5. These cultures are grown at 34 degrees Celsius for 16-24 hours. 10 ml of this culture was inoculated into 500 ml shake flasks with baffles containing 100 ml fermentation medium consisting of per liter: 70 g glucose. H20; 25 g hydrolyzed casein; 12.5 g yeast extract; 1 g KH2P04; 2 g K2S04; 0.5 g MgS04.7H20; 0.03 g ZnCI2; 0.02 g CaCI2; 0.01 g MnS04.4H20; 0.3 g FeS04.7H20; 10 ml penicillin (5000 IU/ml)/Streptomycin (5000UG/ml); adjusted to pH5.6. These cultures are grown at 34 degrees Celsius until all glucose was depleted (usually after 4-7 days). Samples taken from the fermentation broth are centrifuged (10 min at 5000 x g) in a swinging bucket centrifuge and supernatants collected and filtered over a 0.2 μηη filter (Nalgene)
Supernatants are analysed for expression of the polypeptide of the invention by SDS-PAGE and total polypeptide measurements and assayed in an appropriate assay, such as a cellulase activity assay. In case of another (enzyme) activity a suitable assay can be used which are known in the art. A. niger supernatants containing polypeptide of the invention are spiked on top of TEC-210 or 4E-mix and analysed in a corn-stover activity assay. Spiking of the protein of the invention shows increased hydrolysis of corn stover compared to controls in which the protein of the invention is not spiked in.
Example 2: Construction of a R. emersonii expression vectors.
This example describes the construction of an expression construct for overexpression of the protein of the invention in R. emersonii. The expression cassette is targeted integrated into the RePepA locus as described in PCT/EP2013/055051 .
Two vectors are constructed according to routine cloning procedures for targeting into the RePepA locus. The insert fragments of both vectors together can be applied in the so-called "bipartite gene-targeting" method (Nielsen et al., 2006, Efficient PCR-based gene targeting with a recyclable marker for Aspergillus nidulans. Fungal Genet Biol 43(1 ):54-64). This method is using two non-functional DNA fragments of a selection marker which are overlapping (see also WO20081 13847 for further details of the bipartite method) together with gene-targeting sequences. Upon correct homologous recombination the selection marker becomes functional by integration at a homologous target locus. As also detailed in WO 20081 13847, two different deletion vectors, Te pep.bbn and pEBA1006, were designed and constructed to be able to provide the two overlapping DNA molecules for bipartite gene-targeting. Te pep.bbn and pEBA1006 are described in PCT/EP2013/055051.
The ccdB gene in vector Te pep.bbn is replaced by the protein of the invention- expression cassettes according to routine cloning procedures. R. emersonii promoter 2, represented by SEQ ID NO: 33731 , is cloned upstream of the R. emersonii protein coding region with A. nidulans amdS terminator, generating construct pEBA. The A. nidulans amdS terminator sequence is represented by SEQ ID NO: 33732. A schematic representation of pEBA for overexpression of the Gene of interest (GOI, corresponding to SEQ ID NO: 20501 to 32240) being the protein of the invention is shown in Figure 3.
Example 3: Overexpression of the protein of the invention in Rasamsonia emersonii
Linear DNA of pEBA and pEBA1006 are isolated and used to transform Rasamsonia emersonii using method as described earlier in WO201 1/054899 in a Ku80 deletion strain obtained as described in PCT/EP2013/055051. The linear DNAs can integrate together into the genome at the RePepA locus, thus substituting the RePepA gene by the protein of the invention and ble gene. Transformants are selected on phleomycin media and colony purified and tested according to procedures as described in WO201 1/054899. Growing colonies are diagnosed by PCR for integration at the RePepA locus using a primer in the gpdA promoter of the deletion cassette and a primer directed against the genomic sequence directly upstream of the 5' targeting region. Candidate transformants in which RePepA is replaced by the protein of the invention/We cassettes are obtained.
Spores of the protein of the invention-transformants are fermented in shake flasks as described in General methods for Rasamsonia emersonii. Supernatants are analysed for expression of the protein of the invention by SDS-PAGE and total protein measurements 3¾64 -
and assayed in an appropriate assay, such as a cellulase activity assay. In case of another enzyme activity a suitable assay can be used which are known in the art.
Example 4 Construction of R. emersonii deletion vectors.
This example describes the construction of vectors for deletion of the protein of the invention in R. emersonii.
Two replacement vectors are constructed according to routine cloning procedures (see Figures 4 and 5). The insert fragments of both vectors together can be applied in the so called "bipartite gene-targeting" method as described in Example 2. Upon correct homologous recombination the selection marker becomes functional by integration at a homologous target locus. The deletion vectors pEBADEL.1 and pEBADEL2 are designed as described in WO 20081 13847.
The pEBADEL.1 construct comprises a -1200 bp 5' flanking region directly upstream of the ORF encoding the protein of the invention and the 5' part of the ble coding region driven by the A.nidulans gpdA promoter (Figure 4). The pEBADEL2 construct comprises the 3' part of the ble coding region, the A.nidulans trpC terminator, and a -1200 bp 3' flanking region directly downstream of the ORF encoding the protein of the invention (Figure 5).
Example 5: Deletion of the ORF encoding the protein of the invention in Rasamsonia emersonii
Linear DNA of the deletion constructs pEBADEL.1 and pEBADEL2 are isolated and used to transform Rasamsonia emersonii using method as described earlier in WO201 1054899. These linear DNAs can integrate into the genome at the locus of the gene of the invention, thus substituting the ORF encoding the protein of the invention by the ble gene as depicted in Figure 6. Transformants are selected on phleomycin media and colony purified and tested according to procedures as described in WO201 1054899. Growing colonies are diagnosed by PCR for integration at the correct locus using a primer in the gpdA promoter of the deletion cassette and a primer directed against the genomic sequence directly upstream of the 5' targeting region. Knock out strains in which the ORF encoding the protein of the invention is deleted are obtained. Deletion strains are fermented in shake flask as described in Example 3. Supernatants are analysed by SDS-PAGE, total protein measurements and assayed in an appropriate assay, such as a cellulase activity assay.

Claims

A polypeptide which comprises
(a) an amino acid sequence set out in SEQ ID NO: 20501 to 32240;
(b) an amino acid sequence encoded by the nucleic acid sequence of SEQ ID NO: 1 to 20500;
(c) or a variant polypeptide,
wherein the variant polypeptide (i) has at least 70% sequence identity with the sequence set out in SEQ ID NO: 20501 to 32240 or (ii) has an amino acid sequence that differs in 1 , 2, 3, 4, 5, 6, 7, 8, 9, 10, 1 1 or 12 amino acids from the amino acid sequence of SEQ ID NO: 20501 to 32240.
A polypeptide according to claim 1 which has biological activity, preferably is a polypeptide such as an enzyme, more preferably is an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase or is capable to alter or influence the expression of an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase and most preferably is a carbohydrate degrading enzyme and/or carbohydrate hydrolysing enzyme, preferably has an activity mentioned in Table 1 .
A polynucleotide having a nucleic acid sequence whereby the nucleic acid sequence is selected from the group consisting of:
(a) a nucleic acid sequence having at least 70% identity with the nucleic acid sequence of SEQ ID NO: 1 to 20500;
(b) a nucleic acid sequence hybridizing with the complement of the nucleic acid sequence of SEQ ID NO: 1 to 20500;
(c) a nucleic acid sequence encoding (i) the amino acid sequence of SEQ ID NO: 20501 to 32240, (ii) an amino acid sequence having at least 70% identity with the amino acid sequence of SEQ ID NO: 20501 to 32240, or (iii) an amino acid sequence that differs in 1 ,
2,
3,
4, 5, 6, 7, 8, 9, 10, 1 1 or 12 amino acids from the amino acid sequence of SEQ ID NO: 20501 to 32240; or
(d) a nucleotide sequence which is the reverse complement of a nucleotide sequence as defined in (a), (b) or (c).
A polynucleotide of claim 3 having a nucleic acid sequence coding for a polypeptide which has biological activity, preferably the polypeptide is a polypeptide such as an enzyme, more preferably is an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase or is capable to alter or influence the expression of an oxidoreductase, transferase, hydrolase, lyase, isomerase or ligase and most preferably is a carbohydrate degrading enzyme and/or carbohydrate hydrolysing enzyme, preferably has an activity mentioned in Table 1 .
5. A nucleic acid construct or vector comprising the polynucleotide of claim 3 or 4.
6. A recombinant cell comprising the polynucleotide of claim 3 or 4 or a nucleic acid construct or vector of claim 5.
7. A recombinant cell wherein the polynucleotide according to claim 3 or 4 is mutated or deleted from the genome to obtain lower or no expression of the polypeptide encoded by said polynucleotide compared to the cell wherein the polynucleotide according to claim 3 or 4 is not mutated or deleted from the genome.
8. A recombinant cell according to claim 6 or 7 which is a fungal cell, preferably a fungal cell selected from the group consisting of the genera Acremonium, Agaricus, Aspergillus, Aureobasidium, Chrysosporium, Coprinus, Cryptococcus, Filibasidium, Fusarium, Humicola, Magnaporthe, Mucor, Myceliophthora, Neocallimastix, Neurospora, Paecilomyces, Penicillium, Piromyces, Panerochaete, Pleurotus, Schizophyllum, Talaromyces, Rasamsonia, Saccharomyces, Thermoascus, Thielavia, Tolypocladium, and Trichoderma.
9. A recombinant cell according to any one of claims 6 to 8 wherein one or more gene of the cell is deleted, knocked-out or disrupted in full or in part, or is lower or not expressed compared to the native or starting cell, preferably by altering the promoter and wherein optionally the gene encodes for a protease.
10. A recombinant cell wherein the polynucleotide according to claim 3 or 4 is overexpressed compared to the native or starting cell, preferably by altering the promoter or by introducing one or more copies of polynucleotide.
1 1 . A method for the preparation of the polypeptide according to claim 1 or 2 which comprises cultivating a cell according to any one of the claims 6 to 9 under conditions which allow for expression of said polypeptide and, optionally, recovering the expressed polypeptide.
12. A composition comprising: (i) the polypeptide according to claim 1 or 2 and; (ii) a cellulase and/or a hemicellulase and/or a pectinase, preferably the cellulase is a GH61 , cellobiohydrolase, cellobiohydrolase I, cellobiohydrolase II, endo-3-1 ,4- glucanase, β-glucosidase or β-(1 ,3)(1 ,4)-glucanase and/or the hemicellulase is an endoxylanase, β-xylosidase, a-L-arabinofuranosidase, a-D-glucuronidase feruloyl esterase, coumaroyl esterase, a-galactosidase, β-galactosidase, β- mannanase or β-mannosidase.
A method for the treatment of a substrate comprising cellulose and/or hemicellulose, optionally a plant material, which method comprises contacting the substrate with the polypeptide of claim 1 or 2 and/or a composition of claim 12. Use of the polypeptide of claim 1 or 2 and/or a composition of claim 12 to produce sugar from a lignocellulosic material
A polynucleotide coding for a signal sequence having a sequence set out in SEQ ID NO: 32241 to 33730 or having a sequence that differs 1 , 2 or 3 amino acids from the sequence set out in SEQ ID NO: 32241 to 33730.
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