EA005402B1 - Соединения пиримидин-4-она, способ их получения и содержащие их фармацевтические композиции - Google Patents

Соединения пиримидин-4-она, способ их получения и содержащие их фармацевтические композиции Download PDF

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Publication number
EA005402B1
EA005402B1 EA200200379A EA200200379A EA005402B1 EA 005402 B1 EA005402 B1 EA 005402B1 EA 200200379 A EA200200379 A EA 200200379A EA 200200379 A EA200200379 A EA 200200379A EA 005402 B1 EA005402 B1 EA 005402B1
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EA
Eurasian Patent Office
Prior art keywords
branched
linear
formula
compound
compounds
Prior art date
Application number
EA200200379A
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English (en)
Russian (ru)
Other versions
EA200200379A2 (ru
EA200200379A3 (ru
Inventor
Жильбер Лавие
Тьерри Дюбюффе
Оивье Мюлле
Марк Миллан
Анн Декэн
Морисетт Брокко
Original Assignee
Ле Лаборатуар Сервье
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Application filed by Ле Лаборатуар Сервье filed Critical Ле Лаборатуар Сервье
Publication of EA200200379A2 publication Critical patent/EA200200379A2/ru
Publication of EA200200379A3 publication Critical patent/EA200200379A3/ru
Publication of EA005402B1 publication Critical patent/EA005402B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
EA200200379A 2001-04-18 2002-04-17 Соединения пиримидин-4-она, способ их получения и содержащие их фармацевтические композиции EA005402B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0105216A FR2823752B1 (fr) 2001-04-18 2001-04-18 Nouveaux derives de pyrimidin-4-ones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (3)

Publication Number Publication Date
EA200200379A2 EA200200379A2 (ru) 2002-10-31
EA200200379A3 EA200200379A3 (ru) 2002-12-26
EA005402B1 true EA005402B1 (ru) 2005-02-24

Family

ID=8862407

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200379A EA005402B1 (ru) 2001-04-18 2002-04-17 Соединения пиримидин-4-она, способ их получения и содержащие их фармацевтические композиции

Country Status (23)

Country Link
US (1) US6747032B2 (fr)
EP (1) EP1256583B1 (fr)
JP (1) JP3781698B2 (fr)
CN (1) CN1181075C (fr)
AR (1) AR034308A1 (fr)
AT (1) ATE301662T1 (fr)
AU (1) AU781663B2 (fr)
BR (1) BR0201312A (fr)
CA (1) CA2383315C (fr)
DE (1) DE60205424T2 (fr)
DK (1) DK1256583T3 (fr)
EA (1) EA005402B1 (fr)
ES (1) ES2246380T3 (fr)
FR (1) FR2823752B1 (fr)
HK (1) HK1049669A1 (fr)
HU (1) HUP0201255A3 (fr)
MX (1) MXPA02003849A (fr)
NO (1) NO328014B1 (fr)
NZ (1) NZ518425A (fr)
PL (1) PL207047B1 (fr)
PT (1) PT1256583E (fr)
SI (1) SI1256583T1 (fr)
ZA (1) ZA200203086B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2233472B1 (fr) * 2006-03-28 2014-01-15 Atir Holding S.A. Composés hétérocycliques et leurs utilisations dans le traitement de troubles sexuels
EP2697206B1 (fr) 2011-04-10 2019-04-03 Atir Holding S.A. Composés hétérocycliques et leurs utilisations dans le traitement de troubles sexuels
JP2016509066A (ja) * 2013-02-22 2016-03-24 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ アダプター関連キナーゼ１（ａａｋ１）の阻害剤としての５ｈ−クロメノ［３，４−ｃ］ピリジン

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0691342A1 (fr) * 1994-07-06 1996-01-10 Adir Et Compagnie Nouveaux dérivés de benzopyrane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
EP0887350A1 (fr) * 1997-06-24 1998-12-30 Adir Et Compagnie Nouveaux dérivés chroméniques, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE236158T1 (de) * 1999-11-12 2003-04-15 Neurogen Corp Bicyclische und tricyclische heteroaromatische verbindungen

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0691342A1 (fr) * 1994-07-06 1996-01-10 Adir Et Compagnie Nouveaux dérivés de benzopyrane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
US5663191A (en) * 1994-07-06 1997-09-02 Adir Et Compagnie Benzopyran compounds as 5HT2C receptor antagonists
EP0887350A1 (fr) * 1997-06-24 1998-12-30 Adir Et Compagnie Nouveaux dérivés chroméniques, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
SI1256583T1 (sl) 2005-12-31
HK1049669A1 (en) 2003-05-23
DK1256583T3 (da) 2005-10-31
AR034308A1 (es) 2004-02-18
NZ518425A (en) 2003-08-29
CN1181075C (zh) 2004-12-22
JP2002356486A (ja) 2002-12-13
ZA200203086B (en) 2002-10-28
HU0201255D0 (fr) 2002-06-29
NO20021806L (no) 2002-10-21
DE60205424D1 (de) 2005-09-15
PT1256583E (pt) 2005-10-31
CA2383315C (fr) 2008-02-05
AU781663B2 (en) 2005-06-02
HUP0201255A2 (hu) 2002-12-28
EP1256583B1 (fr) 2005-08-10
FR2823752A1 (fr) 2002-10-25
MXPA02003849A (es) 2003-07-14
PL353511A1 (en) 2002-10-21
ATE301662T1 (de) 2005-08-15
DE60205424T2 (de) 2006-07-13
US6747032B2 (en) 2004-06-08
ES2246380T3 (es) 2006-02-16
JP3781698B2 (ja) 2006-05-31
EA200200379A2 (ru) 2002-10-31
CN1381456A (zh) 2002-11-27
NO328014B1 (no) 2009-11-09
CA2383315A1 (fr) 2002-10-18
US20030087916A1 (en) 2003-05-08
EP1256583A1 (fr) 2002-11-13
NO20021806D0 (no) 2002-04-17
FR2823752B1 (fr) 2004-10-22
BR0201312A (pt) 2003-06-10
EA200200379A3 (ru) 2002-12-26
PL207047B1 (pl) 2010-10-29
AU3440602A (en) 2002-10-24
HUP0201255A3 (en) 2003-02-28

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU