EA005034B1 - Производные тиооксиндола - Google Patents

Производные тиооксиндола Download PDF

Info

Publication number
EA005034B1
EA005034B1 EA200101180A EA200101180A EA005034B1 EA 005034 B1 EA005034 B1 EA 005034B1 EA 200101180 A EA200101180 A EA 200101180A EA 200101180 A EA200101180 A EA 200101180A EA 005034 B1 EA005034 B1 EA 005034B1
Authority
EA
Eurasian Patent Office
Prior art keywords
alkyl
substituted
group
alkoxy
indole
Prior art date
Application number
EA200101180A
Other languages
English (en)
Russian (ru)
Other versions
EA200101180A1 (ru
Inventor
Эндрю Фенсам
Пувен Жанг
Марси С. Коко
Джей Э. Вроубел
Джеймс П. Эдвардс
Тодд К. Джоунс
Кристофер М. Тегли
Лин Жи
Эвард Дж. Меленски
Original Assignee
Америкэн Хоум Продактс Корпорейшн
Лиганд Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/552,033 external-priority patent/US6355648B1/en
Application filed by Америкэн Хоум Продактс Корпорейшн, Лиганд Фармасьютикалз, Инк. filed Critical Америкэн Хоум Продактс Корпорейшн
Publication of EA200101180A1 publication Critical patent/EA200101180A1/ru
Publication of EA005034B1 publication Critical patent/EA005034B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
EA200101180A 1999-05-04 2000-05-01 Производные тиооксиндола EA005034B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17225999P 1999-05-04 1999-05-04
US09/552,033 US6355648B1 (en) 1999-05-04 2000-04-19 Thio-oxindole derivatives
PCT/US2000/011630 WO2000066555A1 (en) 1999-05-04 2000-05-01 Thio-oxindole derivatives

Publications (2)

Publication Number Publication Date
EA200101180A1 EA200101180A1 (ru) 2002-04-25
EA005034B1 true EA005034B1 (ru) 2004-10-28

Family

ID=26867898

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200101180A EA005034B1 (ru) 1999-05-04 2000-05-01 Производные тиооксиндола

Country Status (18)

Country Link
EP (1) EP1181275A1 (zh)
JP (1) JP2002543182A (zh)
KR (1) KR20020000636A (zh)
CN (1) CN1143847C (zh)
AU (1) AU767762B2 (zh)
BG (1) BG106078A (zh)
BR (1) BR0010216A (zh)
CA (1) CA2371633A1 (zh)
CZ (1) CZ20013950A3 (zh)
EA (1) EA005034B1 (zh)
GE (1) GEP20043266B (zh)
HU (1) HUP0200993A3 (zh)
MX (1) MXPA01011285A (zh)
NO (1) NO320912B1 (zh)
NZ (1) NZ515351A (zh)
PL (1) PL351407A1 (zh)
SK (1) SK15902001A3 (zh)
TR (1) TR200103288T2 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA06011695A (es) * 2004-04-08 2006-12-14 Wyeth Corp Metodos para minimizar las impurezas de tioamida.
DK1732921T3 (da) * 2004-04-08 2009-02-23 Wyeth Corp Thiomidderivater som progesteronreceptormodulatorer
GB201113538D0 (en) * 2011-08-04 2011-09-21 Karobio Ab Novel estrogen receptor ligands
CN104995194B (zh) * 2012-10-12 2017-08-29 学校法人冲绳科学技术大学院大学学园 螺环吲哚衍生物及其制备方法
US10118890B2 (en) 2014-10-10 2018-11-06 The Research Foundation For The State University Of New York Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration
WO2018064557A1 (en) * 2016-09-30 2018-04-05 Epizyme, Inc. Substituted fused bi- or tri- heterocyclic compounds as ehmt2 inhibitors

Also Published As

Publication number Publication date
NO20015380L (no) 2002-01-03
AU767762B2 (en) 2003-11-20
SK15902001A3 (sk) 2002-11-06
KR20020000636A (ko) 2002-01-05
CN1349499A (zh) 2002-05-15
CN1143847C (zh) 2004-03-31
NO320912B1 (no) 2006-02-13
MXPA01011285A (es) 2003-09-04
NZ515351A (en) 2004-01-30
EA200101180A1 (ru) 2002-04-25
JP2002543182A (ja) 2002-12-17
GEP20043266B (en) 2004-06-25
TR200103288T2 (tr) 2002-04-22
EP1181275A1 (en) 2002-02-27
CZ20013950A3 (cs) 2002-06-12
BR0010216A (pt) 2002-03-19
PL351407A1 (en) 2003-04-22
AU4681400A (en) 2000-11-17
CA2371633A1 (en) 2000-11-09
BG106078A (en) 2002-05-31
HUP0200993A2 (hu) 2002-07-29
NO20015380D0 (no) 2001-11-02
HUP0200993A3 (en) 2003-05-28

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Legal Events

Date Code Title Description
PD4A Registration of transfer of a eurasian patent in accordance with the succession in title
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU